Growth hormone GH - Biotech, Pharma and Life Science Channel
PubMed Articles
Hepatoma-derived growth factor (HDGF), a heparin-binding growth factor, has a wide range of biological functions, including mitogenic activity and vascular development. Recent studies demonstrated tha...
PTPN4 negatively regulates CrkI in human cell lines.
PTPN4 is a widely expressed non-receptor protein tyrosine phosphatase. Although its overexpression inhibits cell growth, the proteins with which it interacts to regulate cell growth are unknown. In th...
2-Hydroxychalcone and xanthohumol inhibit invasion of triple negative breast cancer cells.
Breast cancer is estimated as one of the most common causes of cancer death among women. In particular, triple negative breast cancers (TNBCs), which do not express the genes for estrogen/progesterone...
ErbB3 silencing reduces osteosarcoma cell proliferation and tumor growth in vivo.
Osteosarcoma is the most common primary bone tumor in children and adults. Despite improved prognosis, resistance to chemotherapy remains responsible for failure of osteosarcoma treatment. The identif...
This paper describes a tilted-target RF magnetron sputter deposition system to grow nanoparticles in a controlled way. With detailed characterization of ultra-high density (up to 1.1 × 10(13) cm(-...
Energy medicine (EM) provides a new medical choice for patients, and its advantages are the noninvasive detection and nondrug treatment. An electromagnetic signal, a kind of EM, induced from antibioti...
Progesterone signalling in breast cancer: a neglected hormone coming into the limelight.
Understanding the biology of the breast and how ovarian hormones impinge on it is key to rational new approaches in breast cancer prevention and therapy. Because of the success of selective oestrogen...
Hormone replacement therapy and risk of meningioma in women: a meta-analysis.
PURPOSE: The relationship between hormone replacement therapy (HRT) and the incidence of meningioma in women has been investigated in several epidemiologic studies, but their results were not entirely...
Campylobacter jejuni NCTC11168 does not produce any endogenous siderophores of its own yet requires the CfrA enterobactin transporter for in vivo colonization. In addition, the genome of C. jejuni NCT...
We have evaluated the impact of aluminum (Al) on germination, relative root growth, Al accumulation in roots tips, H2O2 levels, plasma membrane integrity, pigment levels, protein content, and the acti...
News Articles
Avoiding Type 2 Diabetes With The Help Of Fish Oil Supplements
Widely-used fish oil supplements modestly increase amounts of a hormone that is associated with lower risk of diabetes and heart disease, according to a study accepted for publication in The Endocrine...
Malnutrition exacerbates Giardia infection in mice
Giardia is a common parasite that frequently infects young children in the developing world. It is commonly encountered through contaminated food, soil, or water. The parasite lives inside the intest...
HRT Use: New Guidelines From the British Menopause Society
The British Menopause Society and Women's Health Concern has issued updated guidelines on hormone replacement therapy to clarify its use, as well as its benefits and risks. Medscape Medical News
Hormone levels may provide key to understanding psychological disorders in women
Women at a particular stage in their monthly menstrual cycle may be more vulnerable to some of the psychological side-effects associated with stressful experiences, according to a study from UCL.
ACOG: Hormone therapy not recommended to prevent CHD
(HealthDay)—Menopausal hormone therapy should not be used for prevention of coronary heart disease, according to a Committee Opinion from the American College of Obstetricians and Gynecologists (ACO...
Antares Pharma to Present at the Deutsche Bank Securities, Inc. 38th Annual Health Care Conference
Antares Pharma, Inc. (NASDAQ: ATRS) today announced that Paul K. Wotton, Ph.D., President and Chief Executive Officer, will present at the Deutsche Bank Securities, Inc. 38th Annu...
Mother Nature Outsmarts Monsanto Corn
The claim that GMOs reduce pesticide use -- a main selling point -- should be abandoned by the industry that is gobbling up dramatic pesticide sales growth in response to hardy plant pests rapidly ado...
Breast cancer enzyme may slow tumour growth
"Cancer cell enzymes shown to act as 'good cops'," is the headline on the BBC News website. The BBC reports on laboratory research into an enzyme called MMP-8 and its effects on breast canc...
The British Menopause Society and Women's Health Concern have released updated guidelines on Hormone Replacement Therapy (HRT) to provide clarity around the role of HRT, the benefits and the risks. Th...
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Companies
Based in Princeton, N.J., and Paris, Stentys has developed a new generation of stents for the treatment of acute myocardial infarction. Founded by Jacques Séguin, M.D., Ph.D.,...
IRI Consulting provides strategic insights and actionable recommendations to leverage growth with support from IRIâs proprietary, granular data, analytics and technology asse...
BIO and ABFA and ABO and A4A and AFBF and Growth Energy and Pew Charitable Trusts
BIO represents more than 1,100 biotechnology companies, academic institutions, state biotechnology centers and related organizations across the United States and in more than 30 o...
BioNova - The Nova Scotia Biotechnology and Life Sciences Industry Association
BioNova was incorporated in 1993 in response to rapid growth in Nova Scotia’s biotechnology and life sciences sector. Since that time, we have advanced alongside our members to offer advocacy and de...
The GfK Group (GfK = Growth from Knowledge) is a well-respected member of the global market research industry. Established more than 70 years ago, originally as the non-profit "Association for Consume...
Cellmid is an Australian biotechnology company developing innovative novel therapies and diagnostic tests for inflammatory diseases, heart attack and cancer. Cellmid holds the lar...
TheAmerican Association of Clinical Endocrinologists (AACE)
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
Dendreon Corporation is a biotechnology company whose mission is to target cancer and transform lives through the discovery, development, commercialization and manufacturing of no...
Analysis Group, Inc. provides economic, financial, and business strategy consulting to leading law firms, Fortune 500 companies, and government agencies. We assist law firms with...
Crocker Ventures (www.crockerventures.com) is an independent, privately-held life science and healthcare investment firm that funds promising seed- and early-stage life science te...
Clinical Trials
Pamidronate to Treat Osteogenesis Imperfecta in Children
This study will evaluate the effect of pamidronate-a drug that decreases bone resorption (breakdown)-on osteogenesis imperfecta. This is a genetic disorder of collagen, the major protein...
Pelvic Pain in Women With Endometriosis
This study will examine pelvic pain associated with endometriosis and explore better approaches to treatment. In women with endometriosis, uterine tissue grows outside the uterus. Standa...
Screening Evaluation for Women With Postpartum Depression
This study evaluates the relationship between mood changes and hormones in women with postpartum depression (PPD). This is an observational study; volunteers who participate will not rece...
RATIONALE: Dutasteride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase II trial is studying how well dutasteride works in tr...
Vorinostat and Gemcitabine in Treating Patients With Metastatic or Unresectable Solid Tumors
This phase I trial is studying the side effects and best dose of vorinostat and gemcitabine in treating patients with metastatic or unresectable solid tumors. Drugs used in chemotherapy, s...
This study will evaluate the safety and effectiveness of insulin-like growth factor-1 (IGF-1) to treat patients with X-linked severe combined immunodeficiency (XSCID). Those who have XSCID...
Exercise and Metformin in Colorectal and Breast Cancer Survivors
Metformin is a medication that is commonly used in the treatment of diabetes. Recently small studies in cancer patients without diabetes suggest that metformin may benefit in lowering ins...
RATIONALE: Aromatase inhibitors, such as letrozole, prevent the formation of estradiol, a female hormone. Giving letrozole together with goserelin, leuprolide, or surgery may be an effecti...
Tipifarnib may stop the growth of breast cancer by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Drugs used in chemotherapy, such as paclitax...
This study will evaluate whether the drug mifepristone can improve the symptoms of Cushing's syndrome in people with ectopic adrenal corticotrophin hormone (ACTH) secretion. Cushing's synd...
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Medical and Biotech [MESH] Definitions
Luteinization
Formation of CORPUS LUTEUM. This process includes capillary invasion of the ruptured OVARIAN FOLLICLE, hypertrophy of the GRANULOSA CELLS and the THECA CELLS, and the production of PROGESTERONE. Luteinization is regulated by LUTEINIZING HORMONE.
Factor For Inversion Stimulation Protein
A highly abundant DNA binding protein whose expression is strongly correlated with the growth phase of bacteria. The protein plays a role in regulating DNA topology and activation of RIBOSOMAL RNA transcription. It was originally identified as a factor required for inversion stimulation by the Hin recombinase of SALMONELLA and Gin site-specific recombinase of BACTERIOPHAGE MU.
Ephrin-a5
A GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin found in developing tectum. It has been shown to mediate the bundling of cortical axons and repel the axonal growth of retinal ganglia axons. It is found in a variety of adult tissues of BRAIN; HEART; and KIDNEY.
Thyroid Hormone Receptors Alpha
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRA gene (also known as NR1A1, THRA1, ERBA or ERBA1 gene) as several isoforms produced by alternative splicing.
Thyroid Hormone Receptors Beta
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME.
