Heart Failure - Biotech, Pharma and Life Science Channel
PubMed Articles
In girls and young women, irradiation of the ovaries can reduce the number of viable ovarian primordial follicles, which may lead to premature ovarian failure (POF) and subsequently to sterility. One...
This study sought to determine the risk of ischemic stroke (IS)/thromboembolism (TE) associated with renal impairment and its incremental predictive value over established risk stratification scores (...
The study aimed to evaluate inclacumab for the reduction of myocardial damage during a percutaneous coronary intervention (PCI) in patients with non-ST-segment elevation myocardial infarction.
Traditional Chinese Medicine (TCM) operates on the general principle that compatible components of different herbal decoction may work together to synergistically enhance therapeutic efficacy or reduc...
The role of redox signaling in epigenetics and cardiovascular disease.
Abstract Significance: The term epigenetics refers to the changes in the phenotype and gene expression that occur without alterations in the DNA sequence. There is a rapidly growing body of evidence t...
The role of plasma Epstein-Barr virus DNA in the management of recurrent nasopharyngeal carcinoma.
Background: To study the role of plasma Epstein-Barr virus (EBV) DNA in patients with recurrent nasopharyngeal carcinoma (NPC) after previous chemoradiation Study design: prospective Methods: Sixty pa...
Failure of replantation of middle forearm amputation exposed to hot environment.
Aim:To determine whether replacing Mg(2+) in magnesium lithospermate B (Mg-LSB) isolated from danshen (Salvia miltiorrhiza) with other metal ions could affect its potency in inhibition of Na(+)/K(+)-A...
Excessive workplace heat exposures create well-known risks of heat stroke, and it limits the workers' capacity to sustain physical activity. There is very limited evidence available on how these effec...
News Articles
The US Drug Watchdog does not believe a woman victim of a transvaginal mesh failure would want to share a gender specific horror story with a male attorney, so they are offering the contacts for natio...
Study suggests that fluid, sodium restrictions have no effect on weight loss in ADHF patients
A clinical trial of 75 patients hospitalized with acute decompensated heart failure suggests that aggressive fluid and sodium restriction has no effect on weight loss or clinical stability at three da...
Biomarker trio predicts near-term heart risk
(Medical Xpress)—Cardiologists have identified a trio of biomarkers that may predict which patients with heart disease have a high risk of heart attack or death in the next two years.
Aspirin Prescription Algorithm Guides Doctors
A new algorithm has been developed that guides doctors as to how and when they should issue aspirin prescriptions to patients. In the US alone, around 50 million people take one aspirin a day as a hea...
UIC researchers to study gender differences in how the heart uses and stores fat
Researchers at the University of Illinois at Chicago College of Medicine will study gender differences in how the heart uses and stores fat -- its main energy source -- and how changes in fat metaboli...
Noise, Dirty Air May Be Double Whammy for the Heart
MONDAY, May 20 (HealthDay News) -- Air pollution and noise pollution both may boost the risk of heart disease, new research from Germany suggests. "Many studies have looked at air pollution, while ot...
Sports May Be OK With Defibrillator, Study Says
MONDAY, May 20 (HealthDay News) -- Although people with implantable cardioverter defibrillators (ICDs) are often advised to avoid activities more strenuous than golf or bowling, new research suggests...
Performing Heart Surgery Without Opening The Chest
A new medical procedure gives heart patients too frail for open heart surgery another option to fix a common cardiac problem. Grant Boxleitner spoke with one woman who says the procedure saved her...
Genetic markers improve detection of individuals with high risk for CHD
The study comprised over 24,000 Finnish subjects and was led by Professor Samuli Ripatti. The results revealed that a panel of 28 genetic markers improved detection of individuals with high risk for c...
SOUTH SAN FRANCISCO, CA -- (Marketwired) -- 05/21/13 -- Onyx Pharmaceuticals, Inc. (NASDAQ: ONXX) today announced the upcoming presentation of data highlighting Kyprolis® (carfilzomib) for Injection...
Events
None
Companies
Save the Children is the leading independent organization creating lasting change in the lives of children in need in the United States and 120 countries around the world. Save th...
ALung Technologies, Inc. is commercializing artificial lung devices for the treatment of acute and chronic respiratory disorders. The company's Hemolung System, designed to replace or supplement the u...
Lombard Medical Technologies PLC
Lombard Medical Technologies PLC is a global medical technology company focussed on providing innovative endovascular products which broaden clinicians’ treatment options and opportunities for...
MedStar Washington Hospital Center
MedStar Heart Institute, headquartered at MedStar Washington Hospital Center, is a national leader in the research, diagnosis and treatment of cardiovascular disease, and has been...
BIOTRONIK® is a leading European company in the field of biomedical technology. Our main focus is on the business sectors of electrotherapy of the heart and vascular intervention. Our products help p...
The Heart Rhythm Society is the international leader in science, education and advocacy for cardiac arrhythmia professionals and patients, and the primary information resource on heart rhythm disorder...
Cellmid is an Australian biotechnology company developing innovative novel therapies and diagnostic tests for inflammatory diseases, heart attack and cancer. Cellmid holds the lar...
On-X LTI develops heart valve replacements that significantly improve the quality of life for patients. The On-X valve design was awarded a 2002 Medical Device Excellence Award in...
Patient Access Solutions, Inc.
Certain statements in this news release may contain forward-looking information within the meaning of Rule 175 under the Securities Act of 1933 and Rule 3b-6 under the Securities...
Merck and Cardiome Pharma Corp.
In April 2009, Cardiome and Merck announced a collaboration and license agreement for the development and commercialization of vernakalant. The agreement provides Merck, Sharp and...
Clinical Trials
Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression
Background: - Atherosclerosis (thickening of the artery walls caused by cholesterol and other deposits) commonly occurs in the heart vessels and carotid (neck) arteries of adults. This i...
Ventricular Arrhythmias in Uremic Cardiomyopathy
There is a certain gene called sarcoplasmic reticulum gene (SERCA2a), which is found in heart muscle. This gene is also found in blood vessels and skin tissue. When active this gene builds...
Usefulness of Myocardial Deformation Imaging for Trastuzumab-induced Cardiotoxicity
Trastuzumab prolongs survival in patients with human epidermal growth factor receptor type 2-positive breast cancer. Sequential left ventricular (LV) ejection fraction (EF) assessment has...
In this study, newborn babies with respiratory distress syndrome (RDS), receiving oxygen via nasal CPAP, and needing surfactant treatment will be randomized to standard delivery of surfact...
Intervention to Motivate Teens to be a Designated Organ Donor on Driver's License
This study will test the effectiveness of a multimedia campaign to educate ethnic minority teens about the choice to become a designated organ donor on their first driver's license.
Randomized Clinical Trial Comparing Coronary Bypass Grafting With or Without Cardiopulmonary Bypass
Coronary artery bypass grafting (CABG) is a well established treatment modality for patients with coronary artery disease. For 30 years now CABG operations have been performed with the hel...
Prospective, single center, descriptive study in 14 infants/children with multivessel pulmonary vein stenosis stratified for patients with or without underlying cardiac disease. Group 1:...
Vinblastine and Methotrexate in Children With Pulmonary Vein Stenosis
To evaluate the efficacy of the chemotherapeutic agents vinblastine and methotrexate in the treatment of two groups of children with multivessel pulmonary vein stenosis. Group 1 will cont...
Clonidine and Left Ventricular Dysfunction
The objectives of this study are: 1. To evaluate the effect of clonidine, a sympathetic modulator, to reverse cardiac remodeling and to improve hemodynamics in diastolic heart fail...
Iodixanol in Multidetector-Row Computed Tomography-Coronary Angiography (MDCT-CA)
Image quality in coronary artery computed tomography is influenced by the heart rate variation during the examination. The purpose of this clinical trial is to investigate the change in he...
Videos
Congestive Heart Failure - The Basics
A video made as part of the Diagnostics and Therapeutics course for Vanderbilt University Medical Students as part of their module on shortness of breath.
Medical and Biotech [MESH] Definitions
Myocytes, Cardiac
Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).
Adenine Nucleotide Translocator 1
A subtype of mitochondrial ADP, ATP translocase found primarily in heart muscle (MYOCARDIUM) and skeletal muscle (MUSCLE, SKELETAL).
Receptor, Ephb3
An eph family receptor found in a number of tissues including BRAIN; LUNG; KIDNEY; PANCREAS; INTESTINE; and HEART. During embryogenesis EphB3 receptor is expressed at high levels in the brain.
Ephrin-a5
A GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin found in developing tectum. It has been shown to mediate the bundling of cortical axons and repel the axonal growth of retinal ganglia axons. It is found in a variety of adult tissues of BRAIN; HEART; and KIDNEY.
Ephrin-b3
A transmembrane domain containing ephrin. Although originally found to be specific for the EPHB3 RECEPTOR it has since been shown to bind a variety of EPH FAMILY RECEPTORS. During embryogenesis ephrin-B3 is expressed at high levels in the ventral neural tube. In adult tissues, it is found primarily in the BRAIN and HEART.
