Heavy Metal Nephropathy - Biotech, Pharma and Life Science Channel
PubMed Articles
In the title compound, {[Cu(C15H11ClN2O3)(C4H9NO)]n, the Cu(II) cation has square-pyramidal geometry. The morpholine ligand serves as a bridge to link two symmetry-related metal atoms, resulting in an...
Are nonesterified Fatty acids protective in chronic allograft nephropathy?
Heavy neurofilaments (NFH) released from neurons during axonal injury induce a humoral immune response. We measured CSF and serum levels of NFH proteins and anti-NFH IgG antibodies in 19 patients with...
Chitosan-transition metal ions complexes for selective arsenic(V) preconcentration.
Chitosan is naturally occurring bio-polymer having strong affinity towards transition metal ions. Chitosan complexed with transition metal ions takes up inorganic arsenic anions from aqueous medium. I...
Effect of large pore size of multifunctional mesoporous microsphere on removal of heavy metal ions.
Pore size of mesoporous materials is crucial for their surface grafting. This article develops a novel multifunctional microsphere with a large pore size mesoporous silica shell (ca. 10.3nm) and a mag...
A new automatic sequential injection (SI) system for on-line magnetic sorbent extraction coupled with electrothermal atomic absorption spectrometry (ETAAS) has been successfully developed for metal de...
Complex-forming organic ligands in cloud-point extraction of metal ions: a review.
Cloud-point extraction (CPE), an easy, safe, environmentally friendly, rapid and inexpensive methodology for preconcentration and separation of trace metals from aqueous solutions has recently become...
Strong ion exchangers (Dowex 50W-x8 and Dowex 1-x8) were used for the separation and preconcentration of trace amounts of Mo, Sb and V in gasoline samples. Dowex 1-x8 resin was found to be suitable fo...
A Pb and Zn separation method from salts (Na, K, and Cl) in a simulated multicomponent gas generated by the incineration fly ash melting is studied. The heavy metals are separated using a two-stage du...
Degradation of p-nitrophenol in a BES-Fenton system based on limonite.
This study confirmed the feasibility of natural limonite working as the iron catalyst for the PNP wastewater treatment in the BES-Fenton system. After the start-up period of the BES-Fenton systems, ai...
News Articles
The Firm is representing clients in Biomet hip replacement lawsuits who suffered metallosis, premature device failure, and need for revision surgery, allegedly due to the Biomet M2a Magnum hip. New Yo...
California Poison Control Launches First Ever Bilingual Digital Health Pesticide Safety Project
SAN FRANCISCO, June 18, 2013 /PRNewswire-USNewswire/ -- The California Poison Control System (CPCS), the largest single provider of poison control services in the country, today launched a ground brea...
Big Opportunities For Implant Sciences: An Interview With The CEO
By Daniel Lauchheimer:Recently, I conducted an interview with Glenn Bolduc, CEO of Implant Sciences (IMSC.PK). IMSC manufactures explosive trace detection (ETD) equipment for use by security p...
The US Drug Watchdog says, "We want all recipients of a DePuy Pinnacle hip implant device to contact us, so we can provide them with information about a specific blood test that will indicate ele...
A Key Mechanism Discovered That Boosts The Signalling Function Of Neurons In The Brain
Locating a car that's blowing its horn in heavy traffic, channel-hopping between football and a thriller on TV without losing the plot, and not forgetting the start of a sentence by the time we have r...
More Restrictive Teen Tobacco Policies May Reduce Adult Smoking
States that want to reduce rates of adult smoking may consider implementing stringent tobacco restrictions on teens, suggests a new study by researchers at Washington University School of Medicine in...
PTSD - new meaning and relevance
The current wars in the Middle East are pushing research into Post Traumatic Stress Disorder into the headlines, with reports of rates dramatically rising among troops returning from tours. The con...
An innovative material for the green Earth
Ulsan, S. Korea, June 17, 2013 - Researchers from Ulsan National Institute of Science and Technology (UNIST), S. Korea, developed a novel, simple method to synthesize hierarchically nanoporous framewo...
Biometric Authentication Provides Better Mobile Device Security, Heavy Reading Finds
BOSTON, June 17, 2013 /PRNewswire/ -- As mobile devices, smartphones and tablets become more prolific, the need to secure them grows exponentially, and biometric authentication offers that security, a...
Suit filed for Pancreatic Cancer By Use of Byetta, Januvia and Janumet
NEW YORK, June 14, 2013 /PRNewswire/ -- The law firm of Rheingold, Valet, Rheingold, McCartney & Giuffra LLP has just commenced what is believed to be the first suit in New York for the devel...
Events
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Companies
PhosphonicS is a world leading developer of precious metal recovery processes in the Cleantech sector. The company’s precious metal scavenger products enable the recovery and recycling of pre...
Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...
DecImmune Therapeutics was founded by Michael Carroll PhD (The Immune Disease Institute, Harvard Medical School), and Francis Moore Jr. MD (Brigham and Womenâs Hospital, Harv...
NanoIntegris is the worldâs only supplier of 99% pure semiconducting and metallic carbon nanotubes. Founded in 2007, NanoIntegris spun out of Professor Mark Hersamâs res...
KONAMI is a leading developer, publisher and manufacturer of electronic entertainment properties and traditional trading card games. Konamiâs software titles include the popu...
Over the last 10 years, Indo-MIM has become the worldâs largest producer of Metal Injection Molding (MIM) components in the world, with more than 400,000 sq. ft. of manufactu...
We specialize in heavy industrial demolition using the latest techniques and technology for safe and economical results. Whether the plan is to shut down an entire plant or just a...
SentreHEART, Inc., based in Redwood City, California, is a privately held medical device company that manufacturers the LARIAT Suture Delivery Device for remote delivery of a pre-...
Cretex, established in 1917, is a privately held, diversified manufacturing company headquartered in Elk River, Minnesota. The companyâs subsidiaries operate in four major ma...
SlipNOT® Metal Safety Flooring
SlipNOT® manufactures slip resistant metal flooring products which provide high traction working and walking surfaces. SlipNOTâs various product lines include floor plate,...
Clinical Trials
The Effect of the Forced Diuresis With Matched Hydration in Reducing Acute Kidney Injury During TAVI
Evaluating whether forced diuresis with matched hydration will reduce the risk of contrast induced nephropathy in patients undergoing Trancatheter Aortic Valve Implantation (TAVI).
cSBI-M for Young Military Personnel
The goal of this project is to test the efficacy of a computer-facilitated Screening and Brief Intervention system adapted for Military use (cSBI-M) in reducing substance use among 18- to...
Nephrotic Syndrome Study Network
Minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and Membranous nephropathy (MN), generate an enormous individual and societal financial burden, accounting for appr...
Tc-99m Renography and Cisplatin-Induced Nephrotoxicity
Cisplatin is a heavy-metal complex widely used in the treatment of a variety of malignancies, including small cell and non-small cell lung cancer, ovarian, bladder, head and neck, esophage...
Renal Effects of Two Iodinated Contrast Media in Patients at Risk Undergoing Computed Tomography
It is well known that X-ray contrast media can affect kidney function in some patients, especially when administered intra-arterially, and patients who already suffer from reduced kidney f...
Chronic transplant nephropathy and cardiovascular death are the main reasons for loss of transplanted organs after kidney transplantation. Vascular changes, induced by hypertension and/or...
Statins in Proteinuric Nephropathies
End stage renal disease (ESRD) is rapidly growing worldwide. Patients with ESRD have increased morbidity and mortality mostly because of a dramatic excess of cardiovascular disease. Thus,...
The purpose of this study is to determine whether treatment with sirolimus, in combination with low-dose tacrolimus and prednisone, is effective for the treatment of chronic allograft neph...
Caffeine for Apnea of Prematurity (CAP)
At least 5 of every 1000 live-born babies are very premature and weigh only 500 to 1250 grams at birth. Approximately 30-40% of these high-risk infants either die or survive with lasting...
Prevention of Contrast-Induced Nephropathy
Patients with pre-existing kidney disease are at high risk of acute renal failure when exposed to radio-contrast dyes, for example during a cardiac angiogram. The investigators hypothesiz...
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Medical and Biotech [MESH] Definitions
Clathrin Heavy Chains
The heavy chain subunits of clathrin.
Aristolochic Acids
Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINES) by oxidative ring cleavage. The nitro group is a reactive alkylator (ALKYLATING AGENTS) that binds to biological macromolecules. Ingestion by humans is associated with nephropathy (NEPHRITIS). There is no relationship to the similar named aristolochene (SESQUITERPENES).
Integrin Alpha Chains
The alpha subunits of integrin heterodimers (INTEGRINS), which mediate ligand specificity. There are approximately 18 different alpha chains, exhibiting great sequence diversity; several chains are also spliced into alternative isoforms. They possess a long extracellular portion (1200 amino acids) containing a MIDAS (metal ion-dependent adhesion site) motif, and seven 60-amino acid tandem repeats, the last 4 of which form EF HAND MOTIFS. The intracellular portion is short with the exception of INTEGRIN ALPHA4.
Integrin Alpha5
This integrin alpha subunit combines with INTEGRIN BETA1 to form a receptor (INTEGRIN ALPHA5BETA1) that binds FIBRONECTIN and LAMININ. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds.
Integrin Alphav
An alpha integrin with a molecular weight of 160-kDa that is found in a variety of cell types. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds. Integrin alphaV can combine with several different beta subunits to form heterodimers that generally bind to RGD sequence-containing extracellular matrix proteins.
