Helicobacter pylori Infection - Biotech, Pharma and Life Science Channel

04:04 EDT 29th August 2014 | BioPortfolio

PubMed Articles [6762 Associated PubMed Articles listed on BioPortfolio]

Intermittent or sustained systemic inflammation and the preterm brain.

Exposure to perinatal infection and inflammation is associated with an increased risk for neonatal brain damage and developmental disabilities. In this integrated mechanism review, we discuss evidence...

Rapid detection and differentiation of important Campylobacter spp. in poultry samples by dot blot and PCR.

The detection of Campylobacter, the most commonly reported cause of foodborne gastroenteritis in the European Union, is very important for human health. The most commonly recognised risk factor for in...

Effect and mechanisms of curdlan sulfate on inhibiting HBV infection and acting as an HB vaccine adjuvant.

In this study, the effect and mechanisms of curdlan sulfate (CS3) on hepatitis B virus (HBV) infection and promoting immune response of the mice immunized with recombinant hepatitis B surface protein...

Preparation, characterization, and anti-Helicobacter pylori activity of Bi(3+)-Hericium erinaceus polysaccharide complex.

Two new Bi(3+)-Hericium erinaceus polysaccharide (BiHEP) complexes were prepared using Bi(3+) and two purified polysaccharides from H. erinaceus (HEPs), respectively. The complexes were characterized...

Multilocus sequence typing analysis and antibiotic resistance of Clostridium difficile strains isolated from retail meat and humans in Belgium.

Clostridium difficile has been isolated from food animals and meat, specially ground pork and ground beef. The recovered isolates were closely related to C. difficile human strains, indicating that a...

HIV Communication Programs, Condom Use at Sexual Debut, and HIV Infections Averted in South Africa, 2005.

Since the 1990s, communication programs in South Africa have promoted HIV prevention, especially condom use. Although HIV prevalence stabilized after 2000, surveys have not clarified how prevention be...

Construction and functional analysis of Trichoderma harzianum mutants that modulate maize resistance to the pathogen Curvularia lunata.

Agrobacterium tumefaciens-mediated transformation (ATMT) was used to generate an insertional mutant library of the mycelial fungus Trichoderma harzianum. From a total of 450 mutants, six mutants that...

Effectiveness of an Antimicrobial Polymer to Decrease Contamination of Environmental Surfaces in the Clinical Setting.

We performed a real-world, controlled intervention to investigate use of an antimicrobial surface polymer, MSDS Poly, on environmental contamination. Pathogenic bacteria were identified in 18 (90%) of...

Frequency of Interactions and Hand Disinfections among Anesthesiologists While Providing Anesthesia Care in the Operating Room: Induction versus Maintenance.

We evaluated the behaviors of anesthesiologists during induction and maintenance of anesthesia. Contacts with surfaces occurred a mean (±standard error) of 154.8 ± 7.7 and 60 ± 3.1 times per hour d...

Infectious Risk Moments: A Novel, Human Factors-Informed Approach to Infection Prevention.

We pilot tested a novel human factors-informed concept to identify infectious risk moments (IRMs) that occur with high frequency during routine intensive care. Following 30 observation-hours, 28 poten...

News Articles [2316 Associated News Articles listed on BioPortfolio]

AHF Asks “How Many More?” on Latest Porn HIV Infection

Two weeks after Assembly Bill 1576, Isadore Hall’s bill to require condoms in all adult films made in California, failed to get out of the Senate Appropriations Committee—effe...

Fungal vaccine developer Biothera wins SBIR support for preclinical work in infection prevention

US-based biotechnology company Biothera said Wednesday it had received a Small Business Innovation Research (SBIR) grant from the National Institute of Health (NIH), worth USD 150,000 (EUR 113,600), t...

Respiratory Infection Controls for Ebola Patients Unnecessary, May Contribute to Panic, Expert Says

Respiratory infection control measures – which have been adopted by most health agencies to deal with the Ebola epidemic in west Africa – are unnecessary, and may heighten panic and fear a...

Ebola Outbreak Could Infect 20,000 People, U.N. Says

THURSDAY, Aug. 28, 2014 -- The deadly Ebola outbreak hitting four West African nations could eventually infect more than 20,000 people, the World Health Organization announced Thursday. Already the la...

Preventing the Spread of Ebola and Other Infectious Diseases - EPA Approves Florida Company's Disinfectant Use for Infection Control and Biohazards

Zimek announced today the release of the EPA's approval for an antimicrobial product to be used in the company's patented rapid decontamination fogging and micro-misting system. Z...

Complications of tube insertion in ears not worse for kids with cleft lip/palate

Children with cleft lip and/or palate (CLP) have no worse complications from ventilation tube (VT) insertion in their ears to treat otitis media with effusion (OME, a buildup of fluid in the ear) or a...

Respiratory infection controls being used for Ebola patients are unnecessary, may contribute to public panic

Respiratory infection control measures – which have been adopted by most health agencies to deal with the Ebola epidemic in west Africa – are unnecessary, and may heighten panic and fear among the...

Pfizer’s Investigational Vaccine Candidate for Clostridium difficile Receives U.S. Food and Drug Administration Fast Track Designation

Pfizer Inc. (NYSE:PFE) announced today that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to the company’s investigational Clostridium difficile...

Biothera gets NIH funding to further develop fungal vaccine

US-based biotechnology firm Biothera has received a small business innovation research grant from the National Institutes of Health (NIH) to continue development of a fungal vaccine that may protect a...

Respiratory infection control measures being adopted for Ebola patients are unnecessary and may heighten public panic

Respiratory infection control measures – which have been adopted by most health agencies to deal with the Ebola epidemic in west Africa – are unnecessary, and may heighten panic and fear among the...

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Companies [51 Associated Companies listed on BioPortfolio]

Forest Laboratories, Inc. and Furiex Pharmaceuticals, Inc.

Forest Laboratories (NYSE: FRX) is a leading, fully integrated, specialty pharmaceutical company largely focused on the United States market. Forest markets a portfolio of branded...

Ichor Medical Systems, Inc.

Ichor Medical Systems’ TriGrid™ Delivery System (TriGrid) is the first integrated and fully automated device for electroporation-mediated DNA administration in humans. I...

Adenovir Pharma AB

Adenovir Pharma AB is a development company developing new solutions for treatment of infectious diseases affecting the eyes. Adenovir Pharma was founded by researchers at the department of Virolo...

TICK TOCK Naturals LLC

TICK TOCK Naturals™ Organic Insect Repellent is a concentrated 100% organic, chemical-free insect repellent that is also cruelty-free and made in the U.S. It was formulated a...

Special Phage Services

Few inventions in science and medicine have had such a profound effect on human health as the discovery and subsequent development of antibiotics. Following their introduction during World War II ma...

Fidelis Diagnostics, Inc.

Headquartered in Los Angeles, Fidelis Diagnostics is a rapidly growing healthcare company providing a portfolio of innovative diagnostic services to physicians nationwide. Since i...

TYRX®, Inc.

TYRX, Inc. commercializes innovative, implantable combination drug+device products focused on infection control, including the AIGISRx® Antibacterial Envelope, designed to redu...

Progenra, Inc.

Founded in 2002, Progenra is committed to discovering and developing high value medicines based on ubiquitin and ubiquitin-like protein pathways. Its early stage product portfolio...

CytoDyn Inc.

CytoDyn is a biotechnology company focused on developing subcutaneously delivered humanized cell-specific monoclonal antibodies (mAbs) as entry inhibitors for the treatment and pr...

HyGreen, Inc.

HyGreen, Inc. is an innovative technology company whose mission is to improve lives by safeguarding health through technology. Its HyGreen® Hand Hygiene product provides hospit...

Clinical Trials [1409 Associated Clinical Trials listed on BioPortfolio]

A Multiple Dose Study of MK-5172 in Hepatitis C-Infected Participants (MK-5172-010)

This study will compare hepatic pharmacokinetics (PK) derived from liver tissue to plasma PK after administration of MK-5172 to participants with chronic hepatitis C virus (HCV) infection....

CPP Bone Infection Registry

Establish an international registry of over 400 patients with deep infections involving the bone and/or joint from≥20 centers representing all regions of the world with varied hospital a...

Safety, Pharmacokinetics, and Pharmacodynamics of MK-8408 in Participants With Hepatitis C Infection (MK-8408-003)

This is a 3-part study of MK-8408 for participants with hepatitis C infection. Successive participants will be enrolled as dose levels are evaluated to find the maximum safe and well tole...

Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination and Sofosbuvir + Ribavirin for Subjects With Chronic Hepatitis C Virus (HCV) and Inherited Bleeding Disorders

This study will determine the HCV antiviral efficacy, safety, and tolerability of treatment with Ledipasvir/Sofosbuvir (LDV/SOF) fixed-dose combination (FDC) for participants with genotype...

Pilot Study to Assess Efficacy and Safety of Sofosbuvir/Ledipasvir Fixed-dose Combination in Treatment Experienced Subjects With Hepatitis C Virus (HCV) Genotype 1 - HIV Co-infection

Aim of the study is to assess the efficacy and safety of 24 weeks of oral Sofosbuvir/Ledipasvir fixed-dose combination (FDC) in subjects with HCV genotype 1 infection and HIV co-infection,...

Moxifloxacin in Pediatric Subjects With Complicated Intra-abdominal Infection

The primary focus of the study is the evaluation of the safety of treatment with moxifloxacin in a pediatric population 3 months to

Safety of Primaquine + Artemether-lumefantrine in G6PD Deficient Males With an Asymptomatic Malaria Infection (SAFEPRIM)

The purpose of this study is to evaluate the tolerability and safety of increasing doses of primaquine in combination with artemether-lumefantrine in G6PD deficient males with an asymptoma...

Phase III Clinical Study of Efficacy and Safety of Vaccae™ to Prevent Tuberculosis

Mycobacterium Vaccae for Injection (Trade Name "Vaccae") is a kind of bio-products developed by Anhui Zhifei Longcom Biopharmaceutical Co.,Ltd.,and got "The New Drug Certificate "in 1999...

Host Immune Response to Clostridium Difficile Infection in Inflammatory Bowel Disease Patients

The inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn's disease (CD) are chronic conditions affecting approximately 1.4 million Americans. The burden of Clostridium dif...

Study to Determine if Gloving in Addition to Hand Hygiene Will Prevent Invasive Infections and Necrotizing Enterocolitis

The purpose of this study is to compare the additional use of gloves (with handwashing before and after gloving) for all patient contact while infants have intravenous (central or peripher...

Medical and Biotech [MESH] Definitions

Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.

A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).

A species of gram-negative, spiral-shaped bacteria found in the gastric mucosa that is associated with chronic antral gastritis. This bacterium was first discovered in samples removed at endoscopy from patients investigated for HELICOBACTER PYLORI colonization.

Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

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