Helicobacter pylori Infection - Biotech, Pharma and Life Science Channel

08:27 EDT 2nd October 2014 | BioPortfolio

PubMed Articles [6785 Associated PubMed Articles listed on BioPortfolio]

Mouse models of rhinovirus infection and airways disease.

Mouse models are invaluable tools for gaining insight into host immunity during virus infection. Until recently, no practical mouse model for rhinovirus infection was available. Development of infecti...

Reverse genetic engineering of the human rhinovirus serotype 16 genome to introduce an antibody-detectable tag.

The ability to accurately detect viral proteins during infection is essential for virology research, and the lack of specific antibodies can make this detection difficult. Reverse genetic engineering ...

Proteases of human rhinovirus: role in infection.

Human rhinoviruses (HRV) are the major etiological agents of the common cold and asthma exacerbations, with significant worldwide health and economic impact. Although large-scale population vaccinatio...

Application of FCS in Studies of Rhinovirus Receptor Binding and Uncoating.

Fluorescence correlation spectroscopy (FCS) allows determining diffusion and relaxation properties of fluorescent molecules. It requires only extremely small amounts of sample, down to picomolar conce...

Nested-RT-PCR and Multiplex RT-PCR for Diagnosis of Rhinovirus Infection in Clinical Samples.

Human rhinoviruses (HRVs) are positive-stranded RNA viruses belonging to the Enterovirus genus in the family of Picornaviridae. Identification of the specific strain in HRV disease has been difficult ...

Intermittent or sustained systemic inflammation and the preterm brain.

Exposure to perinatal infection and inflammation is associated with an increased risk for neonatal brain damage and developmental disabilities. In this integrated mechanism review, we discuss evidence...

Treatment options beyond IFNα and NUCs for chronic HBV infection: expectations for tomorrow.

Chronic hepatitis B virus (HBV) infection may progress to cirrhosis, hepatocellular carcinoma (HCC) and end-stage liver failure with time. Interruption of this process can only be achieved through eff...

Chronic binge alcohol increases susceptibility to rectal simian immunodeficiency virus infection in macaques.

Reduced expression of Blimp-1 in memory B cells in patients with HIV-1 infection suggests distinct roles of this molecule for B and T cell regulation.

Outcomes and Metrics for Antimicrobial Stewardship: Survey of Physicians and Pharmacists.

We conducted a survey to compare antimicrobial stewardship outcomes considered to be most important with those used in practice as metrics. Respondent opinion of important outcomes compared with those...

News Articles [2306 Associated News Articles listed on BioPortfolio]

Incyte Earns $60 Million Milestone Related to Reimbursement of Jakavi® (ruxolitinib) in Europe

Incyte Corporation (Nasdaq: INCY) announced today that it has earned a $60 million milestone payment from Novartis related to reimbursement of Jakavi® (ruxolitinib) in Europe. In...

Most Effective Weapon against Ebola May Be Telemedicine Technology

GlobalMed CEO calls for the use of telemedicine systems in assessment and treatment to protect healthcare providers and others from EVD infection The Centers for Diseas...

CD Diagnostics, Inc. - Product Pipeline Analysis, 2014 Update

Recently added to the BioPortfolio report store, CD Diagnostics, Inc. - Product Pipeline Analysis, 2014 Update is a new report from GlobalData published on 2014-09-17. This 24-page report is availabl...

Rapid fucosylation of intestinal epithelium sustains host–commensal symbiosis in sickness

Systemic infection induces conserved physiological responses that include both resistance and ‘tolerance of infection’ mechanisms. Temporary anorexia associated with an infection is often benefici...

Immunology: Starve a fever, feed the microbiota

A study finds that the cells lining the gut are modified in response to systemic infection, increasing the host's tolerance to infection in a manner that is dependent on the microorganisms that inhabi...

Ebola companies rise on Texas news

Shares of several Ebola plays settled back Wednesday from double-digit gains in after-hours trading on Tuesday's news the CDC and the Texas Department of State Health Services announced the first U.S....

Medical research: Ebola therapy protects severely ill monkeys

A blend of three monoclonal antibodies has completely protected monkeys against a lethal dose of Ebola virus. Unlike other post-infection therapies, the treatment works even at advanced stages of the ...

How Your Gut Microbes Survive When You're Too Sick to Eat

A bout of the flu can cause even the biggest foodie to abandon the kitchen and forgo regular meals. This change in diet not only affects the waistline, but also starves the good bacteria dwelling in t...

Rhode Island child with Enterovirus dies after infection: officials

BOSTON (Reuters) - A Rhode Island child hospitalized with Enterovirus D68 has died of a bacterial infection in what state public health officials described on Wednesday as an unusual and dangerous com...

Rhode Island child dies of infection tied to Enterovirus D68: officials

BOSTON (Reuters) - A Rhode Island child has died of a bacterial infection associated with Enterovirus D68, state public health officials said on Wednesday.

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Companies [54 Associated Companies listed on BioPortfolio]

Mucosis

Mucosis B.V. is a clinical-stage biotechnology company developing novel vaccines on its proprietary Mimopath® platform technology. The Mimopath® platform is being studied fo...

CherylLeeMD® Sensitive Skin Care

CherylLeeMD® Sensitive Skin Care products are the first skin care products to work with the skin to obtain its optimal equilibrium by simultaneously addressing skin lipid defic...

Ansun BioPharma

Ansun BioPharma is a clinical stage biopharmaceutical company focused on the development of unique host-directed anti-viral therapies for respiratory viruses. Ansun BioPharma has ...

Forest Laboratories, Inc. and Furiex Pharmaceuticals, Inc.

Forest Laboratories (NYSE: FRX) is a leading, fully integrated, specialty pharmaceutical company largely focused on the United States market. Forest markets a portfolio of branded...

Ichor Medical Systems, Inc.

Ichor Medical Systems’ TriGrid™ Delivery System (TriGrid) is the first integrated and fully automated device for electroporation-mediated DNA administration in humans. I...

Adenovir Pharma AB

Adenovir Pharma AB is a development company developing new solutions for treatment of infectious diseases affecting the eyes. Adenovir Pharma was founded by researchers at the department of Virolo...

TICK TOCK Naturals LLC

TICK TOCK Naturals™ Organic Insect Repellent is a concentrated 100% organic, chemical-free insect repellent that is also cruelty-free and made in the U.S. It was formulated a...

Special Phage Services

Few inventions in science and medicine have had such a profound effect on human health as the discovery and subsequent development of antibiotics. Following their introduction during World War II ma...

Fidelis Diagnostics, Inc.

Headquartered in Los Angeles, Fidelis Diagnostics is a rapidly growing healthcare company providing a portfolio of innovative diagnostic services to physicians nationwide. Since i...

TYRX®, Inc.

TYRX, Inc. commercializes innovative, implantable combination drug+device products focused on infection control, including the AIGISRx® Antibacterial Envelope, designed to redu...

Clinical Trials [1416 Associated Clinical Trials listed on BioPortfolio]

A Study of Vaniprevir (MK-7009) in Participants With Chronic Hepatitis C Infection After Participation in Other Vaniprevir Studies (MK-7009-028)

This study will provide vaniprevir 600 mg or 300 mg twice daily in combination with pegylated interferon (peg-IFN) and ribavirin (RBV) to participants with chronic hepatitis C virus (HCV) ...

EPOCH and Rituximab to Treat Non-Hodgkin's Lymphoma in Patients With HIV Infection

Background: - HIV-infected patients have a weakened immune system, and chemotherapy, which is used to treat lymphoma, probably causes further damage to the immune system. ...

First Study to Evaluate the Capacity of Maraviroc Drug to Protect Against HIV Infection in Samples of Rectal Mucosa From Healthy Volunteers

Pre-exposure prophylaxis (PrEP) is a method of preventing HIV infection through the use of antiretroviral (ARV) medications before exposure to HIV. This study will assess the potential of ...

Erlotinib Hydrochloride in Treating Non-Small Cell Lung Cancer That is Metastatic or Cannot be Removed by Surgery in Patients With HIV Infection

This phase I trial studies the side effects and best dose of erlotinib hydrochloride in treating non-small cell lung cancer that has spread to other parts of the body or cannot be removed ...

MK-8228 (Letermovir) Versus Placebo in the Prevention of Clinically-Significant Cytomegalovirus (CMV) Infection in Adult, CMV-Seropositive Allogeneic Hematopoietic Stem Cell Transplant Recipients (MK-8228-001)

The study will evaluate the efficacy and safety of MK-8228 for the prevention of clinically-significant CMV infection in adult, CMV-seropositive recipients of allogeneic hematopoietic stem...

An Expanded Access Protocol for Subjects Who Have Completed Clinical Studies Involving Maraviroc

This is an open-label protocol designed to provide continued access to maraviroc to only those subjects who have completed previous studies of maraviroc and continue to receive clinical be...

University of Wisconsin Meditation & Exercise Cold Study

The primary goal of this project is to determine whether behavioral training in mindfulness meditation or moderate intensity sustained exercise will lead to reductions in acute respiratory...

Impact of Rapid Detection of MRSA

The objective of this study is to evaluate the impact of the Alere™ PBP2a test combined with pharmacist review of antimicrobial therapy, on clinical outcomes and cost in hospitalized...

Nitazoxanide Plus Ribavirin and Peginterferon for Therapy of Treatment Naive HCV Genotype 1 and HIV Coinfected Subjects

Infection with hepatitis C virus (HCV) can cause liver scarring, or cirrhosis, and this usually occurs more rapidly among people infected with both HCV and human immunodeficiency virus (HI...

Safety, Pharmacokinetics, and Pharmacodynamics of MK-8408 in Participants With Hepatitis C Infection (MK-8408-003)

This is a 3-part study of MK-8408 for participants with hepatitis C infection. Successive participants will be enrolled as dose levels are evaluated to find the maximum safe and well tole...

Medical and Biotech [MESH] Definitions

Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.

A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).

A species of gram-negative, spiral-shaped bacteria found in the gastric mucosa that is associated with chronic antral gastritis. This bacterium was first discovered in samples removed at endoscopy from patients investigated for HELICOBACTER PYLORI colonization.

Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

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