Helicobacter pylori Infection - Biotech, Pharma and Life Science Channel

04:08 EDT 2nd July 2015 | BioPortfolio

PubMed Articles [6751 Associated PubMed Articles listed on BioPortfolio]

Enhanced Antifungal Activity by Ab-Modified Amphotericin B-Loaded Nanoparticles Using a pH-Responsive Block Copolymer.

Fungal infections are an important cause of morbidity and mortality in immunocompromised patients. Amphotericin B (AMB), with broad-spectrum antifungal activity, has long been recognized as a powerful...

An age-structured model for the coupled dynamics of HIV and HSV-2.

Evidence suggests a strong correlation between the prevalence of HSV-2 (genital herpes) and the perseverance of the HIV epidemic. HSV-2 is an incurable viral infection, characterized by periodic react...

Global stability of an age-structured virus dynamics model with Beddington-DeAngelis infection function.

In this paper, we study an age-structured virus dynamics model with Beddington-DeAngelis infection function. An explicit formula for the basic reproductive number R0 of the model is obtained. We inves...

A nosocomial epidemic model with infection of patients due to contaminated rooms.

A model of epidemic bacterial infections in hospitals is developed. The model incorporates the infection of patients and the contamination of healthcare workers due to environmental causes. The model ...

Y-doped zinc oxide (YZO) nanoflowers, microstructural analysis and test their antibacterial activity.

Self-assembled 3D flower-like yttrium-doped zinc oxide (YZO) microstructures composed of nanorods were prepared by hydrothermal-precipitation, and tested their antibacterial activity. The morphologica...

Management of Ventricular Arrhythmias in Patients with Mechanical Ventricular Support Devices.

The use of mechanical ventricular support devices in the management of patients with advanced heart failure continues to increase. These devices have been shown to prolong life as a destination therap...

Incidence of HIV Infection in Young Gay, Bisexual, and Other YMSM: The P18 Cohort Study.

HIV infections continue to rise in a new generation of young gay, bisexual, and other young men who have sex with men (YMSM) despite 3 decades of HIV prevention and recent biomedical technologies to d...

High MIP-1β Levels in Plasma Predict Long-Term Immunological Nonresponse to Suppressive Antiretroviral Therapy in HIV Infection.

HIV-infected patients who fail to reconstitute their CD4 T-cell counts during suppressive antiretroviral therapy (ART) have increased risk of both AIDS-related and non-AIDS-related morbidity and morta...

Bayesian network meta-analysis to evaluate interferon-free treatments in naive patients with genotype 1 hepatitis C virus infection.

Sexual Orientation Identity Disparities in Awareness and Initiation of the Human Papillomavirus Vaccine Among U.S. Women and Girls: A National Survey.

Lesbians and bisexual women are at risk for human papillomavirus (HPV) infection from female and male sexual partners.

News Articles [1920 Associated News Articles listed on BioPortfolio]

AZ completes antibiotics spin-out

AstraZeneca plc (LSE:AZN; NYSE:AZN) completed its previously announced spin-out of its early stage antibiotics programs into stand-alone company Entasis Therapeutics Inc. (Waltham, Mass.). AZ was the ...

Gilead uses Priority Review voucher for HIV regimen

Gilead Sciences Inc. (NASDAQ:GILD) submitted a Priority Review voucher along with an NDA to FDA for a single-tablet regimen combining its Emtriva emtricitabine and tenofovir alafenamide plus Edurant r...

PhilRice Develops Method for Rice Viral Infection Detection

The Philippine Rice Research Institute (PhilRice), with the support of the Department of Agriculture-Biotechnology Program, is developing a better and faster method of virus detection in rice and inse...

Many U.S. AIDS Patients Still Die When 'Opportunistic' Infections Strike

WEDNESDAY, July 1, 2015 -- Even after the advent of powerful medications for suppressing HIV, a new study finds that more than one-third of people in San Francisco who were diagnosed with an AIDS-rela...

Secretory diarrhoea: mechanisms and emerging therapies

Secretory diarrhoeas are a major cause of mortality and morbidity globally, especially in vulnerable populations such as children and the elderly. Diarrhoea has many environmen...

Modelling hepatitis C therapy—predicting effects of treatment

Mathematical modelling of the viral kinetics of hepatitis C infection can help inform clinicians of the optimal treatment regimens to achieve a sustained virologic response. In...

Entasis Debuts with a Portfolio of Drug Candidates to Treat Serious Drug-Resistant Bacterial Infections

Entasis Rounds Out Management Team with Michael E. Fitzgerald Chief Financial Officer and Chris White Chief Business Officer Entasis Therapeutics, a company leveraging ...

Many US AIDS patients still die when 'opportunistic' infections strike

(HealthDay)—Even after the advent of powerful medications for suppressing HIV, a new study finds that more than one-third of people in San Francisco who were diagnosed with an AIDS-related infection...

FDA takes action against unapproved prescription ear drop products

The U.S. Food and Drug Administration today announced its intention to take enforcement action against companies that manufacture and/or distribute certain unapproved prescription ear drop products (k...

Stem cell gene therapy holds promise for eliminating HIV infection

cientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research are one step closer to engineering a tool that could one day arm the body's immune system to fight HIV...

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Companies [58 Associated Companies listed on BioPortfolio]

FlowMetric Diagnostics Inc.

FlowMetric Diagnostics, an affiliate of FlowMetric Inc., based in Doylestown, PA and founded in December 2013, utilizes a flow cytometry-based platform to analyze cell-mediated im...

Ariste Medical, Inc.

Ariste Medical, Inc. is a privately held biotechnology company developing novel, first-in-class, drug-eluting devices to reduce infection, restenosis, and thrombosis. Located in t...

Replicor Inc.

Replicor is a privately held biopharmaceutical company with the most advanced animal and human clinical data in the development of the cure for HBV and HDV. The company is dedicat...

Clarus Linen Systems

Established in 2008, Clarus Linen Systems provides the highest quality linen services to Hospitals, Medical Clinics and Outpatient Facilities throughout the East Coast. A c...

Viamet Pharmaceuticals Inc.

Viamet is a biopharmaceutical company focused on the discovery, development and commercialization of novel antifungal agents based on its proprietary metalloenzyme medicinal chemi...

Great Basin Corporation

Great Basin Corporation is a privately held life sciences company that commercializes breakthrough multiplex chip-based technologies for the molecular, rapid diagnostic testing ma...

Mucosis

Mucosis B.V. is a clinical-stage biotechnology company developing novel vaccines on its proprietary Mimopath® platform technology. The Mimopath® platform is being studied fo...

CherylLeeMD® Sensitive Skin Care

CherylLeeMD® Sensitive Skin Care products are the first skin care products to work with the skin to obtain its optimal equilibrium by simultaneously addressing skin lipid defic...

Ansun BioPharma

Ansun BioPharma is a clinical stage biopharmaceutical company focused on the development of unique host-directed anti-viral therapies for respiratory viruses. Ansun BioPharma has ...

Forest Laboratories, Inc. and Furiex Pharmaceuticals, Inc.

Forest Laboratories (NYSE: FRX) is a leading, fully integrated, specialty pharmaceutical company largely focused on the United States market. Forest markets a portfolio of branded...

Clinical Trials [1623 Associated Clinical Trials listed on BioPortfolio]

Effect of Cytoreductive Chemotherapy and a CCR5 Coreceptor Antagonist on HIV-1 Eradication

Effect on HIV-1 cell reservoirs of the concomitant administration of intensive chemotherapy and the pharmacological blockade of CCR5 coreceptors: a pilot, open, randomized, and controlled ...

Infection, Sepsis and Meningitis in Surinamese Neonates

Suriname is a small developing country in South America with a population of half a million people. Early neonatal death in Suriname is high with 16 per 1000 live births. Unpublished data ...

A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP)

This is a randomized, multicenter, multinational, double-blind study comparing the efficacy and safety of plazomicin compared with meropenem followed by optional oral (PO) therapy in the t...

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination, With or Without Ribavirin, in Egyptian Adults With Chronic Genotype 4 HCV Infection

This study will evaluate the efficacy, safety, and tolerability of ledipasvir/sofosbuvir (LDV/SOF) fixed dose combination (FDC) with or without ribavirin (RBV) in Egyptian adults with chro...

Eradication Rate Between 1- and 2-Week Helicobacter Pylori Eradication Therapy

It is recommended as the first line treatment regimen to eradicate Helicobacter pylori (H. Pylori.), 7 or 14 days treatment of proton pump inhibitor (PPI) based triple therapy consisting o...

Study of Safety and Pharmacokinetics in Healthy Volunteers and Safety, Tolerability and Antiviral Activity of VM-1500 in Patients With Human Immunodeficiency Virus-1 Infection

A combined Phase Ib and IIa randomized, placebo-controlled, double-blind study of VM-1500 in healthy subjects and in patients with HIV-1 infection that are antiretroviral therapy naïve.

Efficacy of High-dose Dual Therapy vs Bismuth-containing Quadruple Therapy for First-line Treatment of Hp Infection

Up to now, there is few randomized, large scale study prospectively and simultaneously comparing the efficacy, adverse effects and patient adherence of high-dose dual therapy (HDDT) and bi...

Respiratory Syncytial Virus Human Challenge in Healthy Adult Volunteers

Background: - Respiratory syncytial virus (RSV) can cause respiratory infections. Some of these can be life-threatening, especially in young children, the elderly, and people with weak im...

Impact of Plasma Levels of Colistin in Patients With Carbapenem Resistant Acinetobacter Baumannii Infection

This study purposed to examine the adequate range of therapeutic concentration for Korean people by observing curative effects, side effects, blood concentration, etc. in treating CRAB-inf...

First Event of Infection by HIV-1 of Uterine Vaginal Tissue

This non-interventional study aims to characterize the cells infected with HIV over time in different types of vagino-uterine tissue.

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Medical and Biotech [MESH] Definitions

Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.

A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).

A species of gram-negative, spiral-shaped bacteria found in the gastric mucosa that is associated with chronic antral gastritis. This bacterium was first discovered in samples removed at endoscopy from patients investigated for HELICOBACTER PYLORI colonization.

Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).


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