Helicobacter pylori Infection - Biotech, Pharma and Life Science Channel

16:50 EDT 29th March 2015 | BioPortfolio

PubMed Articles [6869 Associated PubMed Articles listed on BioPortfolio]

A population model capturing dynamics of tuberculosis granulomas predicts host infection outcomes.

Granulomas play a centric role in tuberculosis (TB) infection progression. Multiple granulomas usually develop within a single host. These granulomas are not synchronized in size or bacteria load, and...

Global stability of a multiple delayed viral infection model with general incidence rate and an application to HIV infection.

In this paper, the dynamical behavior of a viral infection model with general incidence rate and two time delays is studied. By using the Lyapunov functional and LaSalle invariance principle, the glob...

The effect of time delay in plant--pathogen interactions with host demography.

Botanical epidemic models are very important tools to study invasion, persistence and control of diseases. It is well known that limitations arise from considering constant infection rates. We replace...

An SIRS model with differential susceptibility and infectivity on uncorrelated networks.

We propose and study a model for sexually transmitted infections on uncorrelated networks, where both differential susceptibility and infectivity are considered. We first establish the spreading thres...

Optimal information dissemination strategy to promote preventive behaviors in multilayer epidemic networks.

Launching a prevention campaign to contain the spread of infection requires substantial financial investments; therefore, a trade-off exists between suppressing the epidemic and containing costs. Info...

A mathematical model of HTLV-I infection with two time delays.

In this paper, we include two time delays in a mathematical model for the CD8+ cytotoxic T lymphocytes (CTLs) response to the Human T-cell leukaemia virus type I (HTLV-I) infection, where one is the i...

A practitioner's guide to necrotizing fasciitis.

: Necrotizing fasciitis (NF) is a severe bacterial infection that attacks subcutaneous fat tissues, superficial fascia, deep fascia, and muscle. NF is a rare condition with a mortality that warrants n...

Brief Report: Mobility and Circular Migration in Lesotho: Implications for Transmission, Treatment, and Control of a Severe HIV Epidemic.

We analyzed georeferenced data on mobility and HIV infection from the 2009 Demographic and Health Survey of Lesotho. We found ∼50% of the population traveled in the preceding year. By constructing g...

Risk Factors for HCV Acquisition Among HIV-Positive MSM in Belgium.

To better understand risk factors for the sexual transmission of hepatitis C viral (HCV) infection among men who have sex with men (MSM).

Recent trends in type-specific HPV infection rates in the United States.

SUMMARY This study examined recent trends in type-specific HPV infection rates in women referred for HPV typing as part of cervical cancer screening in the United States. HPV analyses were performed f...

News Articles [2238 Associated News Articles listed on BioPortfolio]

Minnesota finds third bird flu infection in commercial poultry

CHICAGO (Reuters) - The U.S. Department of Agriculture on Saturday confirmed the third infection of a virulent strain of avian flu in a commercial poultry flock in Minnesota, the nation's top turkey-p...

APIC statement in support of the National Action Plan for Combating Antibiotic-Resistant Bacteria

Today the Administration released a comprehensive plan that identifies critical actions to be taken by key Federal departments and agencies to combat the rise of antibiotic-resist...

HIV Can Lodge Quickly in Brain After Infection

HIV can establish itself in the brain as soon as four months after initial infection — a finding that dampens hopes of an impending cure for a disease that afflicts more than 35 million people.Read ...

PolyPid withdraws IPO

PolyPid Ltd. (Petach Tikva, Israel) withdrew its proposed IPO on NASDAQ. CBO Asaf Bar said the company is confident it could have gone public under current market conditions, but anticipates undisclos...

Ebola mortality is highest among babies, finds study

Nine in 10 children aged under 12 months who contract Ebola virus disease will die from the infection, new analysis by the World Health Organization has shown.The data, published in the New England......

Infection on the Rise After Transrectal Prostate Biopsy

Infection rates after transrectal prostate biopsy are 'considerably higher' than they were a decade ago, a worldwide study shows. Medscape Medical News

FDA Drug Safety Communication: FDA warns of serious slowing of the heart rate when antiarrhythmic drug amiodarone is used with hepatitis C treatments containing sofosbuvir (Harvoni) or Sovaldi in combination with another Direct Acting Antiviral drug

[03-24-2015] The U.S. Food and Drug Administration (FDA) is warning that serious slowing of the heart rate can occur when the antiarrhythmic drug amiodarone is taken together with either the hepatitis...

New Drug Application for a Single Pack Containing TAKECAB for Eradication of Helicobacter pylori in Japan

Osaka and Tokyo, Japan, March 26, 2015—Takeda Pharmaceutical Company Limited (Head office: Chuo-ku, Osaka; President and COO: Christophe Weber; “Takeda”) and Otsuka Pharmaceutical Co...

PuraCath Medical Presents Study at National Kidney Foundation 2015 Spring Clinical Meetings

Company presents new data on the effectiveness of UV light to purify peritoneal dialysis catheter connections across a wider range of microorganisms that contribute to infections in PD patients Dallas...

Gilead secures approval in Japan for Sovaldi to treat genotype 2 chronic HCV

The Japanese Ministry of Health, Labour and Welfare (MHLW) has approved Gilead Sciences' Sovaldi (sofosbuvir) for the suppression of viremia in patients with genotype 2 chronic hepatitis C virus (HCV)...

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Companies [56 Associated Companies listed on BioPortfolio]

Clarus Linen Systems

Established in 2008, Clarus Linen Systems provides the highest quality linen services to Hospitals, Medical Clinics and Outpatient Facilities throughout the East Coast. A c...

Viamet Pharmaceuticals Inc.

Viamet is a biopharmaceutical company focused on the discovery, development and commercialization of novel antifungal agents based on its proprietary metalloenzyme medicinal chemi...

Great Basin Corporation

Great Basin Corporation is a privately held life sciences company that commercializes breakthrough multiplex chip-based technologies for the molecular, rapid diagnostic testing ma...

Mucosis

Mucosis B.V. is a clinical-stage biotechnology company developing novel vaccines on its proprietary Mimopath® platform technology. The Mimopath® platform is being studied fo...

CherylLeeMD® Sensitive Skin Care

CherylLeeMD® Sensitive Skin Care products are the first skin care products to work with the skin to obtain its optimal equilibrium by simultaneously addressing skin lipid defic...

Ansun BioPharma

Ansun BioPharma is a clinical stage biopharmaceutical company focused on the development of unique host-directed anti-viral therapies for respiratory viruses. Ansun BioPharma has ...

Forest Laboratories, Inc. and Furiex Pharmaceuticals, Inc.

Forest Laboratories (NYSE: FRX) is a leading, fully integrated, specialty pharmaceutical company largely focused on the United States market. Forest markets a portfolio of branded...

Ichor Medical Systems, Inc.

Ichor Medical Systems’ TriGrid™ Delivery System (TriGrid) is the first integrated and fully automated device for electroporation-mediated DNA administration in humans. I...

Adenovir Pharma AB

Adenovir Pharma AB is a development company developing new solutions for treatment of infectious diseases affecting the eyes. Adenovir Pharma was founded by researchers at the department of Virolo...

TICK TOCK Naturals LLC

TICK TOCK Naturals™ Organic Insect Repellent is a concentrated 100% organic, chemical-free insect repellent that is also cruelty-free and made in the U.S. It was formulated a...

Clinical Trials [1527 Associated Clinical Trials listed on BioPortfolio]

A Study in Belgian Children Hospitalized With Respiratory Syncytial Virus Related Acute Respiratory Infections

The purpose of the study is to assess viral kinetics and clinical symptoms kinetics in pediatric patients hospitalized with Respiratory Syncytial Virus (RSV) confirmed lower respiratory t...

Prevention of Nosocomial Bacteremia Among Zambian Neonates

The purpose of this study is to estimate the burden of disease, identify risk factors associated with nosocomial bacteremia among neonates and assess the efficacy of low-cost measures targ...

Sofosbuvir Plus Ribavirin For Acute Hepatitis C in HIV-infected Individuals (SWIFT-C)

People who are recently infected with HCV have a great chance of being cured of the infection when they are treated with a combination of two drugs within the first 6 months of being infec...

Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination in Treatment-Naïve and Treatment-Experienced Subjects With Chronic Genotype 4 or 5 HCV Infection

This study is to evaluate the efficacy, safety, and tolerability of ledipasvir/sofosbuvir (LDV/SOF) fixed-dose combination (FDC) in participants with chronic genotype 4 or 5 hepatitis C vi...

Clinical Outcome in View of Surgical Site Infection (SSI) With Antibacterial Skin Sutures

Background: Poor wound healing and the development of surgical site infection (SSI) continue to occur and remain a significant cause of disability among operated patients. In spite of the ...

Impact of Starting a Dolutegravir-based Regimen on HIV-1 Proviral DNA Reservoir Of Treatment Naïve and Experienced Patients

This is a multi-center prospective study. The primary objective of DRONE study is to investigate the change of the size of HIV-1 DNA reservoir in blood from baseline to week 48 (W48) in pa...

Pharmacokinetics and Safety of Solithromycin in Adolescents and Children

Pediatric study to evaluate the safety and pharmacokinetics of solithromycin (oral and intravenous) in children ages 0 to 17

Ibrutinib in Treating Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma in Patients With HIV Infection

This phase I trial studies the side effects and best dose of ibrutinib in treating B-cell non-Hodgkin lymphoma that has returned or does not respond to treatment in patients with human imm...

Sofosbuvir and Ribavirin in Patients With Chronic HCV With Cirrhosis and Portal Hypertension With or Without Liver Decompensation

This study will evaluate the antiviral efficacy of combination therapy with sofosbuvir+ribavirin for 48 weeks in adults with compensated and decompensated chronic HCV infection. Approximat...

Cosyntropin Versus Epidural Blood Patch (EBP) for Treatment of Treatment of Post Dural Puncture Headache

PDPH is a common problem after either intentional or unintentional Dural puncture. It is especially common in young female patients and in patients undergoing Lumbar Puncture using the ty...

Medical and Biotech [MESH] Definitions

Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.

A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).

A species of gram-negative, spiral-shaped bacteria found in the gastric mucosa that is associated with chronic antral gastritis. This bacterium was first discovered in samples removed at endoscopy from patients investigated for HELICOBACTER PYLORI colonization.

Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

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