Helicobacter pylori Infection - Biotech, Pharma and Life Science Channel

21:36 EDT 21st October 2014 | BioPortfolio

PubMed Articles [6695 Associated PubMed Articles listed on BioPortfolio]

Mouse models of rhinovirus infection and airways disease.

Mouse models are invaluable tools for gaining insight into host immunity during virus infection. Until recently, no practical mouse model for rhinovirus infection was available. Development of infecti...

Reverse genetic engineering of the human rhinovirus serotype 16 genome to introduce an antibody-detectable tag.

The ability to accurately detect viral proteins during infection is essential for virology research, and the lack of specific antibodies can make this detection difficult. Reverse genetic engineering ...

Proteases of human rhinovirus: role in infection.

Human rhinoviruses (HRV) are the major etiological agents of the common cold and asthma exacerbations, with significant worldwide health and economic impact. Although large-scale population vaccinatio...

Application of FCS in Studies of Rhinovirus Receptor Binding and Uncoating.

Fluorescence correlation spectroscopy (FCS) allows determining diffusion and relaxation properties of fluorescent molecules. It requires only extremely small amounts of sample, down to picomolar conce...

Nested-RT-PCR and Multiplex RT-PCR for Diagnosis of Rhinovirus Infection in Clinical Samples.

Human rhinoviruses (HRVs) are positive-stranded RNA viruses belonging to the Enterovirus genus in the family of Picornaviridae. Identification of the specific strain in HRV disease has been difficult ...

Role of glycosaminoglycans in infectious disease.

Glycosaminoglycans (GAGs) have been shown to bind to a wide variety of microbial pathogens, including viruses, bacteria, parasites, and fungi in vitro. GAGs are thought to promote pathogenesis by faci...

Intermittent or sustained systemic inflammation and the preterm brain.

Exposure to perinatal infection and inflammation is associated with an increased risk for neonatal brain damage and developmental disabilities. In this integrated mechanism review, we discuss evidence...

Hepatitis B in Pregnancy.

Hepatitis B Virus (HBV) infects over 2 billion people worldwide, with approximately 360 million chronically infected. It results in substantial morbidity and mortality, with an estimated 600,000 death...

Treatment options beyond IFNα and NUCs for chronic HBV infection: expectations for tomorrow.

Chronic hepatitis B virus (HBV) infection may progress to cirrhosis, hepatocellular carcinoma (HCC) and end-stage liver failure with time. Interruption of this process can only be achieved through eff...

Letter: inverse correlation between Helicobacter pylori and obesity - a conclusion too early? Authors' reply.

News Articles [2391 Associated News Articles listed on BioPortfolio]

Dr. Ronald Rice Supports Dental Hygiene Month by Educating Burley Area Residents on an Alternative Method for Treating Gum Disease, through Laser Gum Surgery

Dr. Ronald Rice urges patients who are suffering from gum disease symptoms to schedule a consultation at his dental practice in Burley, ID this October in recognition of Dental Hygiene Month. Dr. Rice...

Hospitals’ Struggles To Beat Back Familiar Infections Began Before Ebola Arrived

While Ebola stokes public anxiety, more than one in six hospitals — including some top medical centers — are having trouble stamping out less exotic but sometimes deadly infections, federa...

High Infection Rates Vary By State

This chart shows what proportion of hospitals in each state had higher than average infection rates for at least one type of infection publicly reported by the Centers for Disease Control and Preventi...

Risk of coronary heart disease in patients with HIV infection

Combination antiretroviral therapy (cART) has substantially prolonged the lives of patients with HIV infection, but these individuals have an increased risk of coronary heart disease and myocardial in...

WHO will review its response to Ebola once outbreak is under control

The World Health Organization has said it will review how it responded to the outbreak of Ebola virus disease in west Africa once the infection is under control. Media reports had said that an...

Cumberland Pharmaceuticals To Announce Third Quarter 2014 Financial Results On November 4, 2014

NASHVILLE, Tenn., Oct. 21, 2014 /PRNewswire/ -- Cumberland Pharmaceuticals Inc. (NASDAQ:CPIX) announced today that it will release third quarter 2014 financial results after the market closes on Tuesd...

Exalenz Bioscience Launches Pivotal Study of World’s First Breath-Based Test to Diagnose Clinically Significant Portal Hypertension

Portal hypertension is the most common complication of cirrhosis, accounting for significant morbidity and mortality Multinational study to be conducted in Europe and the...

New Randomized Study Shows 3.15% Chlorhexidine Gluconate/70% Isopropyl Alcohol Solution Most Effective for Disinfecting Needleless Access Sites at 5 Second Scrub Time

ORANGEBURG, N.Y., Oct. 21, 2014 /PRNewswire/ -- Clinical investigators recently released results from the first and only randomized, cross-over, prospective, comparative effectiveness clinical st...

DebMed Supports 28th Annual International Infection Prevention Week

CHARLOTTE, N.C., Oct. 21, 2014 /PRNewswire/ -- In recognition of the importance of infection prevention to patient safety, DebMed® is joining the Association for Professionals in Infection C...

Norovirus stomach bug: Scientists take step towards drug to treat

An experimental drug currently being trialled for influenza and Ebola viruses could have a new target: norovirus, often known as the winter vomiting virus. A team of researchers has shown that the dru...

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Companies [55 Associated Companies listed on BioPortfolio]

Viamet Pharmaceuticals Inc.

Viamet is a biopharmaceutical company focused on the discovery, development and commercialization of novel antifungal agents based on its proprietary metalloenzyme medicinal chemi...

Great Basin Corporation

Great Basin Corporation is a privately held life sciences company that commercializes breakthrough multiplex chip-based technologies for the molecular, rapid diagnostic testing ma...

Mucosis

Mucosis B.V. is a clinical-stage biotechnology company developing novel vaccines on its proprietary Mimopath® platform technology. The Mimopath® platform is being studied fo...

CherylLeeMD® Sensitive Skin Care

CherylLeeMD® Sensitive Skin Care products are the first skin care products to work with the skin to obtain its optimal equilibrium by simultaneously addressing skin lipid defic...

Ansun BioPharma

Ansun BioPharma is a clinical stage biopharmaceutical company focused on the development of unique host-directed anti-viral therapies for respiratory viruses. Ansun BioPharma has ...

Forest Laboratories, Inc. and Furiex Pharmaceuticals, Inc.

Forest Laboratories (NYSE: FRX) is a leading, fully integrated, specialty pharmaceutical company largely focused on the United States market. Forest markets a portfolio of branded...

Ichor Medical Systems, Inc.

Ichor Medical Systems’ TriGrid™ Delivery System (TriGrid) is the first integrated and fully automated device for electroporation-mediated DNA administration in humans. I...

Adenovir Pharma AB

Adenovir Pharma AB is a development company developing new solutions for treatment of infectious diseases affecting the eyes. Adenovir Pharma was founded by researchers at the department of Virolo...

TICK TOCK Naturals LLC

TICK TOCK Naturals™ Organic Insect Repellent is a concentrated 100% organic, chemical-free insect repellent that is also cruelty-free and made in the U.S. It was formulated a...

Special Phage Services

Few inventions in science and medicine have had such a profound effect on human health as the discovery and subsequent development of antibiotics. Following their introduction during World War II ma...

Clinical Trials [1431 Associated Clinical Trials listed on BioPortfolio]

A Study of MK-6072 and MK-3415A in Participants Receiving Antibiotic Therapy for Clostridium Difficile Infection (MK-3415A-002)

MK-3415A is the combination of monoclonal antibodies to Clostridium (C.) difficile toxin A (MK-3415) and toxin B (MK-6072). This study will investigate whether: 1) treatment with MK-6072 o...

Civamide Nasal Solution for Postherpetic Neuralgia of the Trigeminal Nerve

Herpes zoster (commonly referred to as "shingles") results from the reactivation of the varicella-zoster virus acquired during a primary infection, usually chickenpox. The virus lays dorm...

Screening for Latent Tuberculosis Infection (LTBI) in US Army Recruits

The overall objective of this study is to assess the feasibility and potential impact of using a targeted testing approach and 2 interferon-gamma release assays (IGRA) to screen for latent...

Safety, Antiviral Effect and PK of BI 207127 + BI 201335 +/- RBV for 4 up to 40 Weeks in Patients With Chronic HCV Genotype 1 Infection

The substances BI 201335 and BI 207127 are being developed for the treatment of chronic hepatitis C virus infection. BI 201335 and BI 207127 work by preventing the virus from replicating. ...

Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin in Subjects With Chronic Genotype 1 HCV Who Participated in a Prior Gilead-Sponsored HCV Treatment Study

This study is to evaluate the efficacy, safety, and tolerability of ledipasvir/sofosbuvir fixed-dose combination (LDV/SOF FDC) with or without ribavirin (RBV) in participants with chronic ...

L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract to Prevent Postoperative Urinary Tract Infection.

This study will include women who will undergo pelvic reconstructive surgery and/or anti-incontinence sling procedures. Patients will be randomized to the combination of L-methionine, Hib...

Comparison of Sofosbuvir/GS-5816 Fixed Dose Combination for 12 Weeks With Sofosbuvir and Ribavirin for 24 Weeks in Adults With Chronic Genotype 3 HCV Infection

This study will evaluate the safety, tolerability, and efficacy of treatment with sofosbuvir (SOF)/GS-5816 fixed dose combination (FDC) for 12 weeks compared to treatment with SOF plus rib...

Safety, Pharmacokinetics, and Pharmacodynamics of MK-8408 in Participants With Hepatitis C Infection (MK-8408-003)

This is a 3-part study of MK-8408 for participants with hepatitis C infection. Successive participants will be enrolled as dose levels are evaluated to find the maximum safe and well tole...

Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination and Sofosbuvir + Ribavirin for Subjects With Chronic Hepatitis C Virus (HCV) and Inherited Bleeding Disorders

This study will determine the HCV antiviral efficacy, safety, and tolerability of treatment with Ledipasvir/Sofosbuvir (LDV/SOF) fixed-dose combination (FDC) for participants with genotype...

Safety of Primaquine + Artemether-lumefantrine in G6PD Deficient Males With an Asymptomatic Malaria Infection (SAFEPRIM)

The purpose of this study is to evaluate the tolerability and safety of increasing doses of primaquine in combination with artemether-lumefantrine in G6PD deficient males with an asymptoma...

Medical and Biotech [MESH] Definitions

Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.

A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).

A species of gram-negative, spiral-shaped bacteria found in the gastric mucosa that is associated with chronic antral gastritis. This bacterium was first discovered in samples removed at endoscopy from patients investigated for HELICOBACTER PYLORI colonization.

Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

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