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Helicobacter pylori Infection - Biotech, Pharma and Life Science Channel

20:47 EDT 23rd April 2014 | BioPortfolio

PubMed Articles [4978 Associated PubMed Articles listed on BioPortfolio]

Intermittent or sustained systemic inflammation and the preterm brain.

Exposure to perinatal infection and inflammation is associated with an increased risk for neonatal brain damage and developmental disabilities. In this integrated mechanism review, we discuss evidence...

Multifocal Cellulitis due to Disseminated Neisseria Gonorrhoeae in a Male Patient.

We report a rare case of disseminated gonococcal infection in a 37-year-old man presenting with multifocal cellulitis. The patient presented with fever and painful swelling of the right foot and left...

Helminth/Parasite treatment of multiple sclerosis.

Epidemiological studies suggest that autoimmune diseases, such as multiple sclerosis (MS), are less frequent in individuals who are helminth carriers. This observation has been tested in murine models...

Spondyloarthritis in sub-saharan Africa.

Spondyloarthritis (SpA) is generally uncommon in sub-Saharan Africa, in part because of the rarity of HLA-B27 in this region. However, the relationship between HLA-B27 and SpA, particularly ankylosing...

Time-resolved cellular effects induced by TcdA from Clostridium difficile.

The anaerobe Clostridium difficile is a common pathogen that causes infection of the colon leading to diarrhea or pseudomembranous colitis. Its major virulence factors are toxin A (TcdA) and toxin B (...

Effect of cultivars, Fusarium strains and storage temperature on trichothecenes production in inoculated potato tubers.

Four trichothecenes (Fus-X, 3ADON, DAS and T-2) were detected in potato tubers inoculated with Fusarium spp. by UPLC-MS/MS. The influence of cultivars, Fusarium strains and storage temperature on tric...

Influence of temperature on infection, growth, and mycotoxin production by Fusarium langsethiae and F. sporotrichioides in durum wheat.

Information concerning the temperature requirements of the species causing Fusarium head blight of small grains is essential for understanding which species cause the disease in different areas and ye...

Reply to "CD8+ T Cells Are Essential for Controlling Acute Friend Virus Infection in C57BL/6 Mice".

CD8+ T Cells Are Essential for Controlling Acute Friend Retrovirus Infection in C57BL/6 Mice.

Synopsis of the species of Myxobolus Bütschli, 1882 (Myxozoa: Myxosporea, Myxobolidae) described between 2005 and 2013.

A synopsis of the species of Myxobolus Bütschli, 1882 (Myxozoa, Myxosporea, Myxobolidae) described between 2005 and 2013 is presented, including 112 nominal species. For each species the most importa...

News Articles [2226 Associated News Articles listed on BioPortfolio]

Phenotype and susceptibility to HIV infection of CD4+ Th17 cells in the human female reproductive tract

Nine Cases of MERS-CoV are Reported to WHO

The Ministry of Health of the United Arab Emirates (UAE) has reported to the World Health Organization (WHO) an additional nine laboratory-confirmed cases of infection with Middle East respiratory syn...

Ebola Virus Disease in West Africa: 208 Cases, 136 Deaths

As of April 20, 2014, the Ministry of Health (MOH) of Guinea has reported a cumulative total of 208 clinical cases of Ebola Virus Disease (EVD), including 136 deaths. To date, 169 patients have been t...

Abbvie submits NDA to FDA for hepatitis C drug

US-based biopharmaceutical firm AbbVie has submitted a new drug application (NDA) to the US Food and Drug Administration (FDA) seeking approval for its investigational, all-oral, interferon-free regim...

WetKeys Washable Keyboards Recommends Sealed, Washable Keyboards be Added to WHO’s Hand Hygiene Program

The American Journal of Infection Control recently released a progress report of the implementation of the World Health Organization's Hand Hygiene in Health Care Program. According to the organiz...

Combination tablet offers alternative to interferon for hepatitis C genotype 1 infection

A fixed-dose tablet containing ledipasvir and sofosbuvir is highly effective and well tolerated in a broad range of patients with hepatitis C virus (HCV) genotype 1 infection, show results of two pha...

Patients with advanced liver disease and hepatitis C infection see benefit with multi-drug regimen

An oral multi-drug regimen has shown marked efficacy in patients with cirrhotic liver disease and hepatitis C virus (HCV) genotype 1 infection, according to study results published online in The New...

Vaccine against H. pylori infection is within reach

Researchers from the University of Rhode Island are championing a recent breakthrough in the laboratory with hopes it could lead to a vaccine against the pathogen responsible for stomach cancer and to...

Cabeza (Back of Head) Salomon Huerta

Physicians often encounter patients during times of distress. Moments when their bodies have been broken down by infection, disease, or unintentional injury. Sometimes simple prescriptions of medicati...

Targeting bromodomains: epigenetic readers of lysine acetylation

Inhibiting bromodomains — which are small interaction modules on proteins that assemble acetylation-dependent transcriptional regulatory complexes — could be a way to alter the expression of disea...

Events [1 Associated Events listed on BioPortfolio]

Microbiology & Infectious Diseases Congress, 10 & 11 June 2014, Singapore

The Microbiology & Infectious Diseases Asia Congress, taking place on the 10 & 11 June 2014 in Singapore. This event is an executive platform for experts working in microbiology, bacteriology, mycolog...

Companies [48 Associated Companies listed on BioPortfolio]

Ichor Medical Systems, Inc.

Ichor Medical Systems’ TriGrid™ Delivery System (TriGrid) is the first integrated and fully automated device for electroporation-mediated DNA administration in humans. I...

Adenovir Pharma AB

Adenovir Pharma AB is a development company developing new solutions for treatment of infectious diseases affecting the eyes. Adenovir Pharma was founded by researchers at the department of Virolo...

CytoDyn Inc.

CytoDyn is a biotechnology company focused on developing subcutaneously delivered humanized cell-specific monoclonal antibodies (mAbs) as entry inhibitors for the treatment and pr...

Infect-ERA

Infect-ERA, a consortium funded under the Seventh Framework programme (FP7), is a continuation of the former ERA-NET PathoGenoMics. To date, it includes 14 partners from 11...

Ariste Medical, Inc.

Ariste Medical, Inc. is a privately held biotechnology company developing novel, first-in-class, drug-eluting devices to reduce infection, restenosis, and thrombosis. Located in t...

Emergent BioSolutions

Emergent BioSolutions Inc. is a biopharmaceutical company dedicated to one simple mission—to protect life. We develop, manufacture and commercialize immunobiotics, consisting of vaccines and therape...

TaiMed Biologics Inc.,

TaiMed Biologics, Inc. is a Taiwanese biotech company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious infectious diseases. TaiMed Bio...

Association for Professionals in Infection Control and Epidemiology (APIC)

InSite Vision

InSite Vision is an ophthalmic products company currently focused on ocular infection, glaucoma, and retinal disease. The Company specializes in three platform technologies: topical drug delivery (Dur...

Exalenz Bioscience, Inc.

Exalenz Bioscience develops and markets medical equipment for breath testing for the purposes of diagnosis and management of digestive system and liver conditions. The company sel...

Clinical Trials [1407 Associated Clinical Trials listed on BioPortfolio]

A Multiple Dose Study of MK-5172 in Hepatitis C-Infected Participants (MK-5172-010)

This study will compare hepatic pharmacokinetics (PK) derived from liver tissue to plasma PK after administration of MK-5172 to participants with chronic hepatitis C virus (HCV) infection....

Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination and Sofosbuvir + Ribavirin for Subjects With Chronic Hepatitis C Virus (HCV) and Inherited Bleeding Disorders

This study will determine the HCV antiviral efficacy, safety, and tolerability of treatment with Ledipasvir/Sofosbuvir (LDV/SOF) fixed-dose combination (FDC) for participants with genotype...

Study to Assess the Seroprevalence of Anti-Tat Antibodies in HIV-infected Patients

Tat is a key HIV regulatory protein produced very early after infection, prior to virus integration, and necessary for viral gene expression, cell-to-cell virus transmission and disease pr...

Prophylactic Antibiotic in Treatment of Fingertip Amputation

Fingertip amputation is a common injury. Considerable controversy exists as to whether prophylactic antibiotics are necessary for this injury. The investigators goal was to compare the rat...

Safety, Pharmacokinetics, and Pharmacodynamics of MK-8408 in Participants With Hepatitis C Infection (MK-8408-003)

This is a 3-part study of MK-8408 for participants with hepatitis C infection. Successive participants will be enrolled as dose levels are evaluated to find the maximum safe and well tole...

Characterizing and Comparing the Profile of Microorganisms From Specific Body Sites and Environmental Surfaces in Newly Disinfected Patient Rooms

Overall Aim: To describe and to assess the change in the temporal profile and transmission of microorganisms between patients and environmental surfaces after admission into a newly disinf...

Moxifloxacin in Pediatric Subjects With Complicated Intra-abdominal Infection

The primary focus of the study is the evaluation of the safety of treatment with moxifloxacin in a pediatric population 3 months to

Phase III Clinical Study of Efficacy and Safety of Vaccae™ to Prevent Tuberculosis

Mycobacterium Vaccae for Injection (Trade Name "Vaccae") is a kind of bio-products developed by Anhui Zhifei Longcom Biopharmaceutical Co.,Ltd.,and got "The New Drug Certificate "in 1999...

CPP Bone Infection Registry

Establish an international registry of over 400 patients with deep infections involving the bone and/or joint from≥20 centers representing all regions of the world with varied hospital a...

Characterization of Clonal B Cell Populations in HCV Infection

The purpose of this study is to investigate the mechanism of autoantibody production during chronic hepatitis C virus (HCV) infection. 10-50% of individuals with HCV have symptoms of mixed...

Medical and Biotech [MESH] Definitions

Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.

A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).

A species of gram-negative, spiral-shaped bacteria found in the gastric mucosa that is associated with chronic antral gastritis. This bacterium was first discovered in samples removed at endoscopy from patients investigated for HELICOBACTER PYLORI colonization.

Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

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