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Helicobacter pylori Infection - Biotech, Pharma and Life Science Channel

18:17 EDT 27th June 2016 | BioPortfolio

PubMed Articles [6687 Associated PubMed Articles listed on BioPortfolio]

Time Course of MERS-CoV Infection and Immunity in Dromedary Camels.

Knowledge about immunity to Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels is essential for infection control and vaccination. A longitudinal study of 11 dam-calf pairs sh...

A model of the Ebola epidemics in West Africa incorporating age of infection.

A model of an Ebola epidemic is developed with infected individuals structured according to disease age. The transmission of the infection is tracked by disease age through an initial incubation (expo...

MicroRNAs in Rice Innate Immunity.

MicroRNAs (miRNAs) are short regulatory non-coding RNAs that guide gene silencing in most eukaryotes. They regulate gene expression by triggering sequence-specific cleavage or translational repression...

Microbiological profiles of fungal keratitis: a 10-year study at a tertiary referral center.

Given the rise in cases of fungal keratitis in recent years, this study was performed to better elucidate the microbiological profile, risk factors, and surgical intervention rates of fungal keratitis...

Reactive oxygen species measure for rapid detection of infection in fluids.

Early detection of infection is critical to rapidly starting effective treatment. Diagnosis can be difficult, particularly in the intensive care unit (ICU) population. Because the presence of polymorp...

Aspergillus-positive lower respiratory tract samples in patients with the acute respiratory distress syndrome: a 10-year retrospective study.

The detection of Aspergillus spp. in endotracheal aspirate cultures of mechanically ventilated patients may reflect either colonization or infection. However, little is known about the prevalence and ...

Acute Borrelia infection inducing an APMPPE-like picture.

Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is an uncommon disorder of unknown etiology affecting the retina, the retinal pigment epithelium, and the choroid. Although several e...

Mutation in West Nile Virus Structural Protein prM during Human Infection.

A mutation leading to substitution of a key amino acid in the prM protein of West Nile virus (WNV) occurred during persistent infection of an immunocompetent patient. WNV RNA persisted in the patient'...

Time Lags between Exanthematous Illness Attributed to Zika Virus, Guillain-Barré Syndrome, and Microcephaly, Salvador, Brazil.

Zika virus infection emerged as a public health emergency after increasing evidence for its association with neurologic disorders and congenital malformations. In Salvador, Brazil, outbreaks of acute ...

Functional analysis of human cytomegalovirus UL/b' region using SCID-hu mouse model.

Human cytomegalovirus (HCMV) attenuated strains, Towne, and AD169, differ from prototypic pathogenic strains, such as Toledo, in that they are missing a ∼15-kb segment in the UL/b' region. In contra...

News Articles [2920 Associated News Articles listed on BioPortfolio]

Viral infection: Changing sides to get in

Virions acquire receptor-binding competence by a slow maturation process that involves the translocation of a receptor-binding domain across the membranous viral envelope to avoid non-productive attac...

FDA places Regulus' Hep C drug on clinical hold; shares dive

(Reuters) - Regulus Therapeutics Inc said the U.S. Food and Drug Administration placed on clinical hold the company's drug to treat chronic hepatitis C virus infection, sending its shares plunging 60 ...

Children's plastic toys can 'harbour viruses for hours'

"Plastic toys 'can harbour nasty viruses for hours, raising risk of infection'," the Mail Online reports. New research suggests that enveloped viruses, which have a protective shell, may su...

Anthrax Capsule Vaccine Shown to Protect Against Lethal Inhalational Anthrax in Primate Model

Vaccination with the anthrax capsule--a naturally occurring component of the bacterium that causes the disease--completely protected monkeys from lethal anthrax infection, according to a study publish...

Antibodies to dengue may alter course of Zika virus infection

Scientists at Emory Vaccine Center, in collaboration with investigators from Thailand, have found that people infected with dengue virus develop antibodies that cross-react with Zika virus.

WHO Publishes Profile Profile for Better Zika Tests

The World Health Organization (WHO) declared a Public Health Emergency of International Concern in February 2016, based on the suspected link between Zika virus infection, congenital malformations, an...

CDC Issues Recommendations for Subsequent Zika IgM Antibody Testing

Testing for Zika virus infection using real-time reverse-transcription polymerase chain reaction (rRT-PCR) molecular assays is now commercially available. When requesting Zika rRT-PCR testing from a c...

Disrupted immunity in fetal brain is linked to neurodevelopmental disorders

New research findings in mice may help explain how viral infection during pregnancy raises the risk of autism and schizophrenia in their offspring. The study may explain, among other things, how the m...

Anthrax capsule vaccine offers protection from deadly anthrax infection in monkeys

Vaccination with the anthrax capsule--a naturally occurring component of the bacterium that causes the disease--completely protected monkeys from lethal anthrax infection, according to a study publish...

Infection Control in Implantation of CIEDs

CIED-related infection can be a devastating complication of this procedure. This review presents the current evidence for perioperative prophylaxis and protocols for infection control. Europace

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Companies [66 Associated Companies listed on BioPortfolio]

The FlowMetric Family of Companies

The FlowMetric Family of Companies consist of FlowMetric, Inc. and two additional affiliate companies, FlowMetric Europe, S.p.A. and FlowMetric Diagnostics, Inc. FlowMetric, Inc. ...

GenArraytion, Inc.

Based in Rockville, Md., GenArraytion, Inc. is a privately held, veteran-owned, small business dedicated to the development and commercialization of multiplexed molecular assays f...

Telephus Medical LLC

Telephus Medical, located in San Diego, California, is developing a suite of monoclonal antibody products designed to neutralize key staphylococcal enzymes used to attach to host ...

Calimmune Inc.

Calimmune Inc. is a clinical-stage biotechnology company focused on developing novel gene therapies that have the potential to improve and protect the lives of patients by enhanci...

Hallux Incorporated

Hallux is developing an investigational micro-insert for subungual delivery and treatment of distal lateral subungual onychomycosis. The dosage form is biodegradable and delivers ...

FluGen, Inc.

FluGen, Inc. is a privately held biotechnology company founded in 2005 and based in Madison, WI. The company has been developing novel influenza vaccine technology first invented ...

MeMed Ltd.

MeMed is dedicated to improving patient lives through research, development and commercialization of pioneering products that decode the immune system's distinct responses to diff...

Ironwood Pharmaceuticals, Inc. and AstraZeneca Pharmaceuticals Co., Ltd.

AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines, primarily for the...

FlowMetric Diagnostics Inc.

FlowMetric Diagnostics, an affiliate of FlowMetric Inc., based in Doylestown, PA and founded in December 2013, utilizes a flow cytometry-based platform to analyze cell-mediated im...

Ariste Medical, Inc.

Ariste Medical, Inc. is a privately held biotechnology company developing novel, first-in-class, drug-eluting devices to reduce infection, restenosis, and thrombosis. Located in t...

Clinical Trials [2063 Associated Clinical Trials listed on BioPortfolio]

Staphylokinase and ABO Group Phenotype: New Players in Staphylococcus Aureus Implant-associated Infections Development

The purpose of this study is to identify bacterial and/or clinical features involved in the pathogenesis of Staphylococcus aureus implant-associated infections (IAI). Materials & methods: ...

The HPV Self-test as a Test of Cure in Madagascar

The purpose of this study is to find out whether Self-HPV may be an accurate method for the follow-up of women with a history of HPV infection.

Epidemiology of High-risk HPV Infection in Women Participating in a Pilot Screening Program for Cervical Cancer

Cervical cancer is due to a persistent infection with a group of viruses known as high-risk Human Papillomaviruses (hrHPV). Viral DNA can be easily detected in a cervical sample by a proce...

Zika Virus Infection's Neonatal and Pediatric Consequences in French Department of America

The Zika epidemic has spread into the three French Overseas Departments in the Caribbean (DFAs). It is therefore urgent to set up tools to collect clinical and paraclinical data for the ev...

Hepatitis E Virus Infection in Pediatric Transplantation, a Prevalence Study

Hepatitis E virus (HEV) is an emerging disease. The genotype 1 and 2 are predominant in Asia and Africa, and are responsible for recurrent epidemics. Genotype 3 is the main genotype found ...

Liver Injury by Statins in Patients With History of Hepatitis B Virus Infection

The purpose of this study is to investigate the incidence of liver injury by statins in coronary heart disease (CHD) patients with history of hepatitis B virus (HBV) infection.

BIP Foley in Prevention of CAUTI at Rehab Station

This is a prospective, cross-over, randomized, controlled, partly blinded study evaluating safety and performance of noble metal alloy urinary Catheters (BIP Foley, Bactiguard AB) of both ...

Quality of Life Assessment in Patients Undergoing Prolonged Suppressive Antibiotherapy for Prosthetic Joint Infection.

Prosthetic joint infection (PJI) management is complex and requires prosthesis replacement when symptoms duration is greater than 30 days or debridement with modular set replacement when s...

Bacteriological Setting Before Prosthesis Implantation With One Stage Surgery in Prosthetic Joint Infection

Chronic prosthetic joint infection (PJI) is a devastating complication of arthroplasty and its treatment continues to fuel the debate on how to manage it appropriately. One stage and two ...

The DISCOVER Trial (Diagnosis of Infection in Stem Cell Transplant Patients OVER Time)

Demonstrate that the Karius Infectious Disease Diagnostic Sequencing Assay performed on plasma can accurately detect the microbiologic etiology in febrile allogeneic stem-cell transplant p...

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Medical and Biotech [MESH] Definitions

Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.

A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).

A species of gram-negative, spiral-shaped bacteria found in the gastric mucosa that is associated with chronic antral gastritis. This bacterium was first discovered in samples removed at endoscopy from patients investigated for HELICOBACTER PYLORI colonization.

Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

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