Hepatic Ischemia - Biotech, Pharma and Life Science Channel
PubMed Articles
Unexpectedly low variation in liver ischemia preconditioning study.
Peripheral artery disease (PAD) is characterized by chronic muscle ischemia. Compensatory angiogenesis is minimal within ischemic muscle despite an increase in angiogenic factors. This may occur due t...
Bee pollen and propolis are popular, traditional health foods. The objective of the current study was to investigate the anti-mutagenic, anti-histopathologic and antioxidant effects among water extrac...
Primary Budd-Chiari syndrome in a 3-year-old boy with homozygous factor V Leiden G1691A mutation.
Budd-Chiari syndrome (BCS) is an uncommon disorder characterized by obstruction of hepatic venous outflow. The primary BCS is a rare disease with an incidence about 0.2 per million inhabitants per yea...
Secondary polycythemia with increased production of erythropoietin (EPO) is known to occur in kidney diseases such as hydronephrosis and cystic disease, but the mechanism remains unclear. We report an...
We studied the effects of 2 different dosages of highmolecular- weight poly-gamma-glutamic acid (hm gamma-PGA) derived from Bacillus subtilis chungkookjang on lipid metabolism in a high-fructose diet-...
This study assessed the effects of dietary supplementation with extruded linseed on milk yield and composition, milk fatty acid (FA) profile and renal and hepatic metabolism of grazing goats in mid-la...
Toxic epidermal necrolysis associated with rifaximin.
The case of a patient who developed toxic epidermal necrolysis (TEN) after treatment with rifaximin for hepatic encephalopathy is reported.
Gastrointestinal and hepatic manifestations of mitochondrial disorders.
Inherited defects of oxidative phosphorylation lead to heterogeneous, often multisystem, mitochondrial diseases. This review highlights those mitochondrial syndromes with prominent gastrointestinal an...
Hyperammonemia is a major etiological toxic factor in the development of hepatic encephalopathy. Brain ammonia detoxification occurs primarily in astrocytes by glutamine synthetase (GS), and it has be...
News Articles
Salix Pharmaceuticals Outlines Data Presentations at Digestive Disease Week 2013
Salix Pharmaceuticals, Ltd. (NASDAQ:SLXP) today announced that presentations related to the investigation of two of the Company’s products are scheduled to take place during Dig...
World Congress on Interventional Oncology to Present Live TheraSphere® Administration
Interventional Oncology Team at Northwestern Memorial Hospital to performhepatocellular carcinoma liver-directed treatment with live narration Nordion Inc. (T...
Bayer to Present New Data Across Oncology Portfolio at ASCO 2013
WAYNE, N.J., May 15, 2013 /PRNewswire/ -- Intended for U.S. Media Only -- Bayer HealthCare announced today that new data on the oncology portfolio, including Nexavar® (sorafenib) tablet...
WAYNE, N.J., May 15, 2013 /PRNewswire/ -- Bayer HealthCare announced today that patient enrollment is underway for RESORCE (Regorafenib after Sorafenib in Patients with Hepatocellular Carcinom...
Bioheart Announces Addition of New Corporate Controller
SUNRISE, FL -- (Marketwired) -- 05/15/13 -- Bioheart, Inc. (OTCQB: BHRT) announced today that Ms. Evelyn Flores will join Bioheart as Corporate Controller. A tenured finance and accounting executive,...
SOUTH SAN FRANCISCO, CA -- (Marketwired) -- 05/15/13 -- Onyx Pharmaceuticals, Inc. (NASDAQ: ONXX) today announced the upcoming presentations of data highlighting Nexavar® (sorafenib) tablets, Kyprol...
Dipen J. Parekh, M.D., Receives Urology’s Prestigious Gold Cystoscope Award
Dipen J. Parekh, M.D., professor and Chair of Urology and the Dr. Victor Politano Endowed Chair in Clinical Urology at the University of Miami Miller School of Medicine, is the 20...
A 76-year-old man with a history of diffuse B-cell non-Hodgkins lymphoma and chronic neutropenia and thrombocytopenia presented with a 3-day history of vomiting, abdominal discomfort, and malaise. He...
AnGes looks to raise at least $51.2M
Japanese gene therapy company AnGes MG Inc. (Tokyo:4563) said it hopes to raise at least Y5.1 billion ($51.2 million) through May 19, 2014, through the exercise of 20,000 stock acquisition rights by M...
DELCATH REPORTS 2013 FIRST QUARTER RESULTS
Conference Call and Webcast Today at 4:30 p.m. ET - QUEENSBURY, NY - May 8, 2013 - Delcath Systems, Inc. (NASDAQ: DCTH) today reported financial results and operational highlights for the fiscal fir...
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Companies
Medistem Inc. is a biotechnology company developing technologies related to adult stem cell extraction, manipulation, and use for treating inflammatory and degenerative diseases....
Pluristem is a clinical stage biotechnology company with patented technology for the development and manufacturing of standardized cell therapies derived from the human placenta....
NeurOp, Inc. is an Atlanta-based biopharmaceutical company developing new medicines for central nervous system disorders, including depression, neuropathic pain, ischemia (stroke)...
Cyterix Pharmaceutics, Inc., a privately held cancer therapeutics company, is engaged in the discovery and development of new classes of small molecule prodrugs with improved safe...
BioCardia, Inc., headquartered in San Carlos, CA is a privately-held commercial medical technology company that has developed percutaneous delivery systems for biologics to treat...
âWe are well-positioned to be a dominant competitor in the emerging market for drug-eluting balloons (DEBs) as a first-line therapy for many patients, including those with cr...
THE SAGE GROUP, a research and consulting company, specializes in atherosclerotic disease in the lower limbs, specifically PAD (Peripheral Artery Disease), CLI (Critical Limb Isch...
Hyperion Therapeutics is a privately held pharmaceutical company focused on the development of therapies that address critical unmet needs and underserved patient populations in t...
Clinical Trials
A Multiple Dose Study of MK-5172 in Hepatitis C-Infected Participants (MK-5172-010 AM1)
This study will compare hepatic pharmacokinetics (PK) derived from liver tissue to plasma PK after administration of MK-5172 to participants with chronic hepatitis C virus (HCV) infection....
"Salvage Use" of Recombinant Factor VIIa After Inadequate Haemostasis in Complex Cardiac Surgery
Aims and Hypotheses: This randomised placebo controlled study will test the hypothesis that Recombinant Activated Factor VII (rVIIa) will improve haemostasis after an inadequate response...
This is a prospective, multi-center, randomized, placebo-controlled trial in subjects with histological evidence of > 33% hepatic steatosis or nonalcoholic steatohepatitis (NASH) and chron...
The purpose of this study is to determine whether the addition of bevacizumab, to hepatic arterial therapy with floxuridine (FUDR) and dexamethasone (Dex) (regional chemotherapy), and eith...
With a major liver or pancreas operation, there is a chance that one will require a transfusion of blood products (either red blood cells or plasma). This may be necessary during the oper...
Serum HBV DNA is a referent but insufficient marker of therapeutic follow-up in chronic hepatitis B treatment. Intra hepatic cccDNA disappearance reflects HBV eradication in the liver....
Insulin resistance (IR), a key factor in the development of steatosis, is a common finding in patients with hepatitis C virus (HCV) infection. In patients with genotype 1 infection, IR has...
The aim of this study was assesment of splanchnic and systemic hemodynamic effects of chronic administration (2 month) of spironolactone or propranolol, alone or in association in alcoholi...
Opioid Receptors Influence Ischemia-Reperfusion Injury
The most powerful protective mechanism against ischemia-reperfusion injury other than rapid reperfusion is ischemic preconditioning. Ischemic preconditioning is defined as the development...
The Effect of Caffeine on Ischemic Preconditioning
Ischaemic preconditioning (IP) describes the phenomenon that brief periods of ischaemia render the (myocardial) muscle more resistant to a subsequent more prolonged period of ischaemia and...
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Medical and Biotech [MESH] Definitions
Hypoalbuminemia
A condition in which albumin level in blood (SERUM ALBUMIN) is below the normal range. Hypoalbuminemia may be due to decreased hepatic albumin synthesis, increased albumin catabolism, altered albumin distribution, or albumin loss through the urine (ALBUMINURIA).
Diffusion Magnetic Resonance Imaging
A diagnostic technique that incorporates the measurement of molecular diffusion (such as water or metabolites) for tissue assessment by MRI. The degree of molecular movement can be measured by changes of apparent diffusion coefficient (ADC) with time, as reflected by tissue microstructure. Diffusion MRI has been used to study BRAIN ISCHEMIA and tumor response to treatment.
Liver Abscess, Pyogenic
Single or multiple areas of PUS due to bacterial infection within the hepatic parenchyma. It can be caused by a variety of BACTERIA, local or disseminated from infections elsewhere such as in APPENDICITIS; CHOLECYSTITIS; PERITONITIS; and after LIVER TRANSPLANTATION.
Massive Hepatic Necrosis
Extensive and rapid death of parenchymal cells in the LIVER, often due to exposure to toxic materials. It is characterized by a soft, flabby, yellow-brown wrinkled, and shrunken liver. It was called "acute yellow atrophy".
Echinococcus Multilocularis
A north temperate species of tapeworm (CESTODA) whose adult form infects FOXES and wild RODENTS. The larval form can infect humans producing HEPATIC HYDATID CYSTS.
