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Hepatitis B virus HBV - Biotech, Pharma and Life Science Channel

08:42 EDT 18th May 2013 | BioPortfolio

PubMed Articles [ 7377 Associated PubMed Articles listed on BioPortfolio]

Treatment for hepatitis C virus-induced portal hypertension in leukemic children.

Children with acute leukemia are at high risk of hepatitis C infection, either by immunosuppression secondary to chemotherapy or by multiple transfusions of blood products during the course of the dis...

Notes from the field: transmission of HBV among assisted-living-facility residents - virginia, 2012.

On June 29, 2012, the Rappahannock Area Health District in northwestern Virginia received a report of an acute hepatitis B virus (HBV) infection in an elderly resident of an assisted-living facility (...

Purification of infective baculoviruses by monoliths.

A chromatographic process based on monoliths for purification of infective baculovirus without prior concentration step has been established. Baculovirus produced in Spodoptera frugiperda cells (Sf-9)...

Sofosbuvir for previously untreated chronic hepatitis C infection.

In phase 2 trials, the nucleotide polymerase inhibitor sofosbuvir was effective in previously untreated patients with chronic hepatitis C virus (HCV) genotype 1, 2, or 3 infection.

Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options.

Patients chronically infected with hepatitis C virus (HCV) genotype 2 or 3 for whom treatment with peginterferon is not an option, or who have not had a response to prior interferon treatment, current...

Microbiota Regulates the TLR7 Signaling Pathway Against Respiratory Tract Influenza A Virus Infection.

Although intestinal flora are crucial in maintaining immune homeostasis of the intestine, the role of intestinal flora in immune responses at other mucosal surfaces remains less clear. Here, we show t...

In Vitro and In Vivo Anti-Tobacco Mosaic Virus Activities of Essential Oils and Individual Compounds.

Essential oils are increasingly of interest for use as novel drugs acting as antimicrobial and antiviral agents. In the present study, we report the in vitro antiviral activities of 29 essential oils,...

Transgenic resistance to Bamboo mosaic virus by expression of interfering satellite RNA.

Plant genetic engineering has broadened the options for plant virus resistance and is mostly based on pathogen-derived resistance. Previously, we have shown that interfering satellite RNA (satRNA) of...

Seroprevalence of Bovine Ephemeral Fever Virus in Domesticated and Wildlife Species during Epidemic and Inter-epidemic Periods (2000-2009) in Israel.

Bovine ephemeral fever (BEF) is an economically important vector-borne viral disease of cattle and buffalo. It has been reported from most of the world's tropical and subtropical regions. In the last...

Current and future therapies for hepatitis C virus infection.

News Articles [ 5314 Associated News Articles listed on BioPortfolio]

Pediatrics: HPV Warts Spread from Parents to Kids; polyDNA Recommends Protecting Kids from HPV with Gene-Eden VIR

Children often get warts from family members or classmates rather than from public spaces. (1) polyDNA suggests that parents use Gene-Eden-VIR to help prevent HPV transmission to their children. Roche...

AIDS science at 30: 'Cure' now part of lexicon

Big names in medicine are set to give an upbeat assessment of the war on AIDS on Tuesday, 30 years after French researchers identified the virus that causes the disease.

Why the Precautionary Principal is a Crock. Speed Matters when it comes to Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics

VACCINES Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics

Virus found in Iowa hog population, possibly beyond

WASHINGTON (Reuters) - Cases of porcine epidemic diarrhea (PEDV), a virus associated with diarrhea, vomiting and dehydration in hogs, has been found in Iowa and possibly beyond, U.S. government and pr...

USDA says has detected virus in Iowa hog population

WASHINGTON (Reuters) - USDA's National Veterinary Services Laboratories has detected porcine epidemic diarrhea (PEDV), a virus associated with outbreaks of diarrhea and vomiting, in the Iowa hog popul...

Death toll from new bird flu in China rises to 36: WHO

LONDON (Reuters) - Four more people in China have died from a new strain of bird flu, bringing the death toll from the H7N9 virus to 36 from 131 confirmed cases, the World Health Organization (WHO) sa...

Death toll from new bird flu in China rises to 36 - WHO

LONDON, May 17 (Reuters) - Four more people in China have died from a new strain of bird flu, bringing the death toll from the H7N9 virus to 36 from 131 confirmed cases, the World Health Organisation...

Pending EC decision: AFTOVAXPUR DOE, 1-3 inactivated, purified FMD virus(es) out of a set of 7 (multistrain), Opinion date: 16-May-2013

First influenza vaccine brought to clinical testing

Singapore's Agency for Science, Technology and Research (A*STAR) and Switzerland's Cytos Biotechnology AG today announced that the first healthy volunteer has been dosed in a Phase 1 clinical trial wi...

Twin epidemics: HIV and Hepatitis C in the urban Northeast

A new Yale study looks at the scope and consequences of a burgeoning health problem in the cities of the U.S. Northeast: concurrent infection with both HIV and Hepatitis C (HCV). The study appears onl...

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Companies [ 42 Associated Companies listed on BioPortfolio]

Cell Medica

Cell Medica is a clinical stage cellular therapeutics company engaged in the development and delivery of cellular immunotherapy treatment strategies for infectious disease and can...

Enanta Pharmaceuticals, Inc.

Enanta Phatmaceuticals ARE A RESEARCH AND DEVELOPMENT-FOCUSED BIOTECHNOLOGY COMPANY that uses its robust chemistry-driven approach and drug discovery capabilities to create small molecule drugs in t...

ISICR

The International Society for Interferon and Cytokine Research (ISICR), based in Bethesda, Md., is a non-profit organization devoted to interferon, cytokine and chemokine r...

Profectus BioSciences, Inc.

Profectus BioSciences, Inc. is a technology based vaccine company devoted to the treatment and prevention of chronic viral diseases with a goal of reducing morbidity and mo...

Nexera Medical, Inc.

Nexera Medical Inc. is headquartered in Fort Lauderdale, Florida. The company is engaged in the development, manufacturing, and distribution of antimicrobial respirator and surgic...

Genocea Biosciences, Inc.

Genocea Biosciences is a vaccine discovery and development company targeting major infectious diseases with high unmet medical needs, in which T cell responses help confer protect...

Okairos

Okairos is a clinical-stage biopharmaceutical company, developing genetic vaccines for major infectious diseases - including malaria, hepatitis C, influenza, respiratory syncytial...

Prosetta Antiviral Inc.

Prosetta is a 9-year-old San Francisco-based biotechnology company with an innovative approach to drug discovery. The Prosetta platform emerged from 25 years of basic research on...

GenMark Diagnostics Inc.

GenMark Diagnostics is a leading provider of automated, multiplex molecular diagnostic testing systems that detect and measure DNA and RNA targets to diagnose disease and optimize...

AGTC

AGTC is focused on the research and development of novel therapeutics for patients with unmet medical needs utilizing AGTC’s proprietary, non-pathogenic adeno-associat...

Clinical Trials [ 1704 Associated Clinical Trials listed on BioPortfolio]

Immune Response to Hepatitis C Virus

This study will identify and characterize immune factors involved in hepatitis C infection and elimination of the virus. Individual responses to hepatitis C infection vary; some people ar...

Vaccine Therapy in Treating Patients Who Are Being Considered For a Solid Organ Transplant and Are at Risk For Post-Transplant Lymphoproliferative Disorder

RATIONALE: Vaccines made from a person's white blood cells may help the body build an effective immune response. PURPOSE: This phase I trial is studying the side effects of vaccine therap...

An Open Label Pharmacokinetic, Safety And Efficacy Study Of Maraviroc In Combination With Background Therapy For The Treatment Of HIV-1 Infected, CCR5 -Tropic Children

The primary purpose of this study is to determine the pharmacokinetic properties (what the body does to maraviroc) and to determine a suitable dosing schedule of maraviroc in HIV-1 infecte...

Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy

Background: - Drugs given to treat cancer (chemotherapy) can weaken the human immune system. But it can also become weaker because of aging. Interleukin (IL)-7, a molecule produced natura...

Observational Study of Nevirapine Extended Release in Human Immunodeficiency Virus (HIV) Patients in Daily Clinical Practice

This Post Marketing Surveillance study will be performed as an open-label, prospective, non-interventional, uncontrolled study in Human immunodeficit Virus-1 (HIV-1) infected patients. Dat...

A Phase 2a, Dose-Ranging Study to Evaluate the Safety, Pharmacokinetics and Efficacy of VX-135 With Ribavirin in Treatment-Naïve Subjects With Chronic Hepatitis C

The purpose of the study is to determine the safety, pharmacokinetics and efficacy of orally administered VX-135 with ribavirin in treatment naive subjects with chronic hepatitis C infecti...

Efficacy and Safety of Short Course Therapy With Peginterferon Alpha-2b (PEG-IFN Alfa-2b) and Ribavirin (RBV) for Chronic Hepatitis C (Genotype 4) Participants Achieving a Rapid Virological Response at Week 4 of Treatment (MK-8908B-059 AM1)

The purpose of this study is to assess the efficacy of a short course of therapy (24 weeks) versus standard 48 week treatment in previously untreated adult participants with chronic hepati...

TMC435-TiDP16-C112 - Interaction Trial With Antidepressants

The purpose of this study is to investigate the effect of steady-state concentrations of TMC435 150mg q.d. (once a day) on the steady-state pharmacokinetics of escitalopram 10 mg q.d., and...

A Multiple Dose Study of MK-5172 in Hepatitis C-Infected Participants (MK-5172-010 AM1)

This study will compare hepatic pharmacokinetics (PK) derived from liver tissue to plasma PK after administration of MK-5172 to participants with chronic hepatitis C virus (HCV) infection....

PEG-Interferon a-2b + Ribavirin for Treatment of Patients With Chronic Hepatitis C Who Have Previously Failed to Achieve a Sustained Virologic Response Following Interferon Alfa or Interferon a-2b + Ribavirin Therapy

HRN-003 STUDY SYNOPSIS OBJECTIVE: To compare the Sustained Virologic Response (SVR) of PEGIntron plus ribavirin among patients receiving a fixed dose of PEGIntron versus weighted-adjusted...

Medical and Biotech [MESH] Definitions

Hepatitis A Antigens

Antigens produced by various strains of HEPATITIS A VIRUS such as the human hepatitis A virus (HEPATITIS A VIRUS, HUMAN).

Hepatitis A Antibodies

Antibodies to the HEPATITIS A ANTIGENS including antibodies to envelope, core, and non-structural proteins.

Hepatitis Delta Antigens

Antigens produced by various strains of HEPATITIS D VIRUS.

Virus Inactivation

Inactivation of viruses by non-immune related techniques. They include extremes of pH, HEAT treatment, ultraviolet radiation, IONIZING RADIATION; DESICCATION; ANTISEPTICS; DISINFECTANTS; organic solvents, and DETERGENTS.

Balb 3t3 Cells

Cell lines developed from disaggregated BALB/c mouse embryos. They are extremely sensitive to CONTACT INHIBITION, and highly susceptible to transformation by SV40 VIRUS and murine sarcoma virus (SARCOMA VIRUSES, MURINE).

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