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Hepatitis E virus HEV - Biotech, Pharma and Life Science Channel

02:52 EDT 24th May 2013 | BioPortfolio

PubMed Articles [ 7404 Associated PubMed Articles listed on BioPortfolio]

Treatment for hepatitis C virus-induced portal hypertension in leukemic children.

Children with acute leukemia are at high risk of hepatitis C infection, either by immunosuppression secondary to chemotherapy or by multiple transfusions of blood products during the course of the dis...

IL28B minor allele is associated with a younger age of onset of hepatocellular carcinoma in patients with chronic hepatitis C virus infection.

BACKGROUND: IL28B polymorphisms were shown to be associated with a response to peg-interferon-based treatment in chronic hepatitis C (CHC) and spontaneous clearance. However, little is known about how...

Presence of bacteria in aqueous solution influences virus adsorption on nanoparticles.

Virus contamination in wastewater is usually accompanied by the existence of various bacteria. Nanoparticles (NPs) have been shown to efficiently remove virus. In this study, bacterial cells, supernat...

Facile synthesis of tetrasaccharide aided by fluorous chemistry toward a dengue virus vaccine.

We report the synthesis of a tetrasaccharide with side chain using a light-fluorous-tagged glycosyl donor through the double glycosylation and gradient fluorous solid-phase extraction by adding a litt...

Hepatitis B vaccination status and associated factors among health care workers in Burkina Faso.

Introduction. The purpose of this study was to evaluate anti-HBV vaccination status and factors associated with vaccination against HBV among health care workers in Burkina Faso. Methods. In August an...

Boginia virus, a newfound hantavirus harbored by the Eurasian water shrew (Neomys fodiens) in Poland.

BACKGROUND: Guided by decades-old reports of hantaviral antigens in the Eurasian common shrew (Sorex araneus) and the Eurasian water shrew (Neomys fodiens) in European Russia, we employed RT-PCR to an...

No evidence for the persistence of Schmallenberg virus in overwintering mosquitoes.

In 2011, Schmallenberg virus (SBV), a novel member of the Simbu serogroup, genus Orthobunyavirus, was identified as the causative agent of a disease in ruminants in Europe. Based on the current knowle...

New Route for Fast Detection of Antibodies against Zoonotic Pathogens in Sera of Slaughtered Pigs by Means of Flow-through Chemiluminescence Immunochips.

The research on fast screening methods for antibodies against zoonotic pathogens in slaughter animals is important for food safety in farming and meat-processing industries. As a proof-of-concept stud...

Hepatitis C virus targets the interferon-α JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes.

JAK/STAT signalling is essential for anti-viral immunity, making IFN-α an obvious anti-viral therapeutic. However, many HCV+ patients fail treatment, indicating that the virus blocks successful IFN-Î...

Susac syndrome in a patient with human immunodeficiency virus infection.

News Articles [ 5370 Associated News Articles listed on BioPortfolio]

Debunking 'The Big Lie' About Genetically Engineered Crops

Plums that have been genetically engineered to be resistant to the plum pox virus (Photo credit: Wikipedia)By Henry I. Miller and Graham Brookes, 23 May 2013In spite of two decades of stunning scienti...

Characterization of a third generation lentiviral vector pseudotyped with Nipah virus envelope proteins for endothelial cell transduction

The immunogenicity of virus-derived 2A sequences in immunocompetent individuals

WHO warns countries not to hoard secrets of coronavirus

GENEVA (Reuters) - The World Health Organization (WHO) warned countries with possible cases of the SARS-like novel coronavirus on Thursday that they must share information and not allow commercial lab...

WHO: Scientific red tape mars efforts vs. virus

International efforts to combat a new pneumonia-like virus that has now killed 22 people are being slowed by unclear rules and competition for the potentially profitable rights to disease samples, the...

Respiratory syncytial virus (RSV) infections account for a significant portion of healthcare resources consumed across the US, as the health of vulnerable infants is seriously threatened by the common winter ailment

The new report* looks at respiratory syncytial virus (RSV), one of the most common causes of pediatric respiratory infections. Transmission is seasonal and the virus is spread through the air by an...

BioFront Technologies Receives Funding Through Florida Institute Seed Capital Accelerator Program

Company Based on Technology Developed at Florida State University The Institute for the Commercialization of Public Research (the Institute) announced today that it has finali...

Why Merck Shares Are Cheap And Could Rise To $60

By Trade In Mexico:While many stocks are trading near 52-week highs or at stretched valuations, investors who selectively seek opportunities can find value in this market. For example, Merck (MRK) sha...

WHO: 22 deaths from new SARS-like virus

The World Health Organization says there are now 22 deaths worldwide out of 44 lab-confirmed cases of the new coronavirus. WHO officials have reported another fatal case of the Middle East respirato...

J&J plans filing on more than 10 new drugs by 2017

(Reuters) - Johnson & Johnson said on Thursday it plans to submit more than 10 new products for regulatory approval by 2017, including drugs to treat hepatitis C, immune diseases and schizophrenia, an...

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Companies [ 42 Associated Companies listed on BioPortfolio]

Transgene SA

Transgene (NYSE-Euronext: TNG), a member of the Institut Mérieux Group, is a biopharmaceutical company. It creates, develops and manufactures targeted immunotherapeutics for th...

Transgene

TRANSGENE is a leading integrated gene therapy company, dedicated to the discovery and development of gene delivery technologies and gene therapy products for the treatment of acquired and inherited d...

Cell Medica

Cell Medica is a clinical stage cellular therapeutics company engaged in the development and delivery of cellular immunotherapy treatment strategies for infectious disease and can...

Enanta Pharmaceuticals, Inc.

Enanta Phatmaceuticals ARE A RESEARCH AND DEVELOPMENT-FOCUSED BIOTECHNOLOGY COMPANY that uses its robust chemistry-driven approach and drug discovery capabilities to create small molecule drugs in t...

ISICR

The International Society for Interferon and Cytokine Research (ISICR), based in Bethesda, Md., is a non-profit organization devoted to interferon, cytokine and chemokine r...

Profectus BioSciences, Inc.

Profectus BioSciences, Inc. is a technology based vaccine company devoted to the treatment and prevention of chronic viral diseases with a goal of reducing morbidity and mo...

Nexera Medical, Inc.

Nexera Medical Inc. is headquartered in Fort Lauderdale, Florida. The company is engaged in the development, manufacturing, and distribution of antimicrobial respirator and surgic...

Genocea Biosciences, Inc.

Genocea Biosciences is a vaccine discovery and development company targeting major infectious diseases with high unmet medical needs, in which T cell responses help confer protect...

Okairos

Okairos is a clinical-stage biopharmaceutical company, developing genetic vaccines for major infectious diseases - including malaria, hepatitis C, influenza, respiratory syncytial...

Prosetta Antiviral Inc.

Prosetta is a 9-year-old San Francisco-based biotechnology company with an innovative approach to drug discovery. The Prosetta platform emerged from 25 years of basic research on...

Clinical Trials [ 1704 Associated Clinical Trials listed on BioPortfolio]

Immune Response to Hepatitis C Virus

This study will identify and characterize immune factors involved in hepatitis C infection and elimination of the virus. Individual responses to hepatitis C infection vary; some people ar...

Vaccine Therapy in Treating Patients Who Are Being Considered For a Solid Organ Transplant and Are at Risk For Post-Transplant Lymphoproliferative Disorder

RATIONALE: Vaccines made from a person's white blood cells may help the body build an effective immune response. PURPOSE: This phase I trial is studying the side effects of vaccine therap...

An Open Label Pharmacokinetic, Safety And Efficacy Study Of Maraviroc In Combination With Background Therapy For The Treatment Of HIV-1 Infected, CCR5 -Tropic Children

The primary purpose of this study is to determine the pharmacokinetic properties (what the body does to maraviroc) and to determine a suitable dosing schedule of maraviroc in HIV-1 infecte...

Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy

Background: - Drugs given to treat cancer (chemotherapy) can weaken the human immune system. But it can also become weaker because of aging. Interleukin (IL)-7, a molecule produced natura...

Observational Study of Nevirapine Extended Release in Human Immunodeficiency Virus (HIV) Patients in Daily Clinical Practice

This Post Marketing Surveillance study will be performed as an open-label, prospective, non-interventional, uncontrolled study in Human immunodeficit Virus-1 (HIV-1) infected patients. Dat...

A Multiple Dose Study of MK-5172 in Hepatitis C-Infected Participants (MK-5172-010 AM1)

This study will compare hepatic pharmacokinetics (PK) derived from liver tissue to plasma PK after administration of MK-5172 to participants with chronic hepatitis C virus (HCV) infection....

A Phase 2a, Dose-Ranging Study to Evaluate the Safety, Pharmacokinetics and Efficacy of VX-135 With Ribavirin in Treatment-Naïve Subjects With Chronic Hepatitis C

The purpose of the study is to determine the safety, pharmacokinetics and efficacy of orally administered VX-135 with ribavirin in treatment naive subjects with chronic hepatitis C infecti...

Efficacy and Safety of Short Course Therapy With Peginterferon Alpha-2b (PEG-IFN Alfa-2b) and Ribavirin (RBV) for Chronic Hepatitis C (Genotype 4) Participants Achieving a Rapid Virological Response at Week 4 of Treatment (MK-8908B-059 AM1)

The purpose of this study is to assess the efficacy of a short course of therapy (24 weeks) versus standard 48 week treatment in previously untreated adult participants with chronic hepati...

TMC435-TiDP16-C112 - Interaction Trial With Antidepressants

The purpose of this study is to investigate the effect of steady-state concentrations of TMC435 150mg q.d. (once a day) on the steady-state pharmacokinetics of escitalopram 10 mg q.d., and...

PEG-Interferon a-2b + Ribavirin for Treatment of Patients With Chronic Hepatitis C Who Have Previously Failed to Achieve a Sustained Virologic Response Following Interferon Alfa or Interferon a-2b + Ribavirin Therapy

HRN-003 STUDY SYNOPSIS OBJECTIVE: To compare the Sustained Virologic Response (SVR) of PEGIntron plus ribavirin among patients receiving a fixed dose of PEGIntron versus weighted-adjusted...

Videos

KMA-IDF Oration 2008-Discovery of hepatitis E: The epidemic non-A, non-B hepatitis 25 years later

DISCOVERY OF HEPATITIS E The epidemic non-A, non-B hepatitis 25 years later. Prof. Mohammad Sultan Khuroo, MD, DM, FRCP (Edin.), FACP, Master American Colleg...

Medical and Biotech [MESH] Definitions

Hepatitis A Antigens

Antigens produced by various strains of HEPATITIS A VIRUS such as the human hepatitis A virus (HEPATITIS A VIRUS, HUMAN).

Hepatitis A Antibodies

Antibodies to the HEPATITIS A ANTIGENS including antibodies to envelope, core, and non-structural proteins.

Hepatitis Delta Antigens

Antigens produced by various strains of HEPATITIS D VIRUS.

Virus Inactivation

Inactivation of viruses by non-immune related techniques. They include extremes of pH, HEAT treatment, ultraviolet radiation, IONIZING RADIATION; DESICCATION; ANTISEPTICS; DISINFECTANTS; organic solvents, and DETERGENTS.

Balb 3t3 Cells

Cell lines developed from disaggregated BALB/c mouse embryos. They are extremely sensitive to CONTACT INHIBITION, and highly susceptible to transformation by SV40 VIRUS and murine sarcoma virus (SARCOMA VIRUSES, MURINE).

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