Hepatoblastoma - Biotech, Pharma and Life Science Channel
PubMed Articles
Oridonin, the main active component of Rabdosia rubescens, has antitumor activities in experimental and clinical settings. The aims of the current study were to explore the anticancer abilities of ori...
FAK Inhibition Decreases Hepatoblastoma Survival Both In Vitro and In Vivo.
Hepatoblastoma is the most frequently diagnosed liver tumor of childhood, and children with advanced, metastatic or relapsed disease have a disease-free survival rate under 50%. Focal adhesion kinase...
Mouse liver tumors that harbor activating mutations in Ctnnb1, encoding β-catenin, express high levels of various cytochromes P450 (CYP), including CYP2E1 and CYP1A2. Acetaminophen (AAP) is metaboliz...
Neuroendocrine differentiation in embryonal type hepatoblastoma.
Hepatoblastoma, a malignant tumor which arises occasionally in older children but very rarely in adults, exhibits divergent differentiation with embryonal cells, fetal hepatocytes and immature element...
PURPOSE: Duplex drugs are promising anticancer agents. After in vivo cleavage into active nucleoside analogues, they exert their anti-tumour activity with reduced toxicity and side effects. Here we ev...
Cardiac arrest and possible seizure activity after vincristine injection.
Purpose A case of cardiac arrest and possible seizure activity after vincristine injection in a child is reported. Summary A two-year-old African-American girl with stage IV hepatoblastoma arrived at...
Perinatal detection of familial adenomatous polyposis.
: Hepatoblastoma is an uncommon fetal neoplasm that may represent an isolated malignancy or a component of a familial cancer or syndromic diagnosis.
Pancreatoblastoma in children: diagnosis and therapeutic management.
A recent review of the literature identified more than 150 reported cases of pancreatoblastoma in children. However, the clinical, histological and therapeutic characteristics of this tumour are hard...
Hepatoblastoma in two siblings and familial adenomatous polyposis: causal nexus or coincidence?
Infantile and childhood hepatoblastoma (HB) occurs more frequently in children with hereditary predisposition to familial adenomatous polyposis (FAP) than in the general population. The occurrence of...
News Articles
My brother was diagnosed with hepatoblastoma when I was 4 years old and he was just shy of 2. It wasn't until years (and several cancers) later that we learned he had Gardner syndrome. Over the last 2...
SAN DIEGO, CA -- (Marketwired) -- 04/04/13 -- Vital Therapies, Inc., a development-stage biotechnology company focused on developing the first bio-artificial liver for life-threatening acute liver fa...
Vital Therapies, Inc. Announces Increase in Financing
SAN DIEGO, CA -- (Marketwire) -- 03/25/13 -- Vital Therapies, Inc., a development stage biotechnology company focused on developing the first bio-artificial liver for life-threatening acute liver fai...
Pittsburgh - UPMC Finds Liver Transplantation for Hepatoblastoma on the Rise
A new study from the Children's Hospital of Pittsburgh of UPMC suggests liver transplantation for hepatoblastoma, the most common liver malignancy in children, is on the rise because more tumors are b...
Liver transplantation for hepatoblastoma, the most common liver malignancy in children, is on the rise because more tumors are being detected earlier, improving outcomes for these sick patients, accor...
Study shows increase in liver transplantation for hepatoblastoma
Liver transplantation for hepatoblastoma, the most common liver malignancy in children, is on the rise because more tumors are being detected earlier, improving outcomes for these sick patients, accor...
Effect of sorafenib combined with cytostatic agents on hepatoblastoma cell lines and xenografts
Events
None
Companies
None
Clinical Trials
None
Videos
Right Hepatectomy for right lobe Hepatoblastoma in a child by Dr Hitesh Chavda
Right Hepatectomy for right lobe Hepatoblastoma in a child by Dr Hitesh Chavda.
Medical and Biotech [MESH] Definitions
Hepatoblastoma
A malignant neoplasm occurring in young children, primarily in the liver, composed of tissue resembling embryonal or fetal hepatic epithelium, or mixed epithelial and mesenchymal tissues. (Stedman, 25th ed)
