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Hepatology - Biotech, Pharma and Life Science Channel

12:19 EDT 18th May 2013 | BioPortfolio

Hepatology is the study of liver, gallbladder, biliary tree, and pancreas, and diseases associated with them. This includes viral hepatitis, alcohol damage, cirrhosis and cancer. As modern lifestyles change, with alcoholism and cancer becoming more prominent, the study of hepatology becomes increasingly important.

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News Articles [ 462 Associated News Articles listed on BioPortfolio]

Salix Pharmaceuticals Outlines Data Presentations at Digestive Disease Week 2013

Salix Pharmaceuticals, Ltd. (NASDAQ:SLXP) today announced that presentations related to the investigation of two of the Company’s products are scheduled to take place during Dig...

Mauna Kea Technologies Announces Strongest Scientific Exposure Ever With More Than 40 Communications on Cellvizio(R) at Digestive Disease Week 2013

PARIS -- (Marketwired) -- 05/17/13 -- Mauna Kea Technologies (EURONEXT PARIS: MKEA), leader in the optical biopsy market and developer of Cellvizio®, the fastest way to see cancer, today announced t...

World Congress on Interventional Oncology to Present Live TheraSphere® Administration

Interventional Oncology Team at Northwestern Memorial Hospital to performhepatocellular carcinoma liver-directed treatment with live narration Nordion Inc. (T...

MultiCell Technologies Files U.S. Patent Application for Targeted Delivery of Noncoding Micro RNAs for the Treatment of Liver Cancer

WOONSOCKET, R.I., May 16, 2013 /PRNewswire/ -- MultiCell Technologies, Inc. (OTC Bulletin Board: MCET.OB) is pleased to announce the filing of a U.S. patent application concerning methods and formulat...

Vital Therapies, Inc. Adds Two New Board Members

SAN DIEGO, CA -- (Marketwired) -- 05/16/13 -- Vital Therapies, Inc., a development stage biotechnology company focused on developing the first bio-artificial liver for life-threatening acute liver fa...

Alnylam to Webcast Presentation at 2013 UBS Global Healthcare Conference

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, today announced that management will present a company overview at the 2013 UBS Global He...

Bayer to Present New Data Across Oncology Portfolio at ASCO 2013

WAYNE, N.J., May 15, 2013 /PRNewswire/ -- Intended for U.S. Media Only -- Bayer HealthCare announced today that new data on the oncology portfolio, including Nexavar® (sorafenib) tablet...

Galectin Therapeutics to Hold Conference Call to Provide Update Following Company's Annual Meeting of Shareholders

ATLANTA, May 15, 2013 /PRNewswire/ -- Galectin Therapeutics (NASDAQ: GALT) will host a conference call at 9:30 A.M. Eastern Time on Thursday, May 23, 2013, to provide an update following the Comp...

Bayer Initiates Phase III Trial of Stivarga® (regorafenib) Tablets in Patients with Advanced Liver Cancer

WAYNE, N.J., May 15, 2013 /PRNewswire/ -- Bayer HealthCare announced today that patient enrollment is underway for RESORCE (Regorafenib after Sorafenib in Patients with Hepatocellular Carcinom...

Jennerex Announces Science Translational Medicine Publication Highlighting Pexa-Vec's Ability to Induce Functional Anti-Cancer Immunity in Patients With Diverse Tumor Types

SAN FRANCISCO, CA -- (Marketwired) -- 05/15/13 -- Jennerex Biotherapeutics, Inc., a private, clinical-stage biotechnology company focused on the development and commercialization of best-in-class tar...

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Companies [ 24 Associated Companies listed on BioPortfolio]

Provectus Pharmaceuticals, Inc.

Provectus Pharmaceuticals specializes in developing oncology and dermatology therapies. Its lead oncology agent, PV-10, is designed to selectively target and destroy cancer cells...

Alliqua, Inc.

Alliqua, Inc. (“Alliqua”), formerly HepaLife Technologies, Inc., (OTCBB: HPLF) (FWB: HL1), is an advanced biomedical products company focused on the development and manu...

Pure Inventions

Pure Inventions was founded in 2003 by Certified Clinical Nutritionists and Nutritional Consultants, Lynne Gerhards and Lori Mulligan. The comprehensive line of liquid extracts wa...

Galectin Therapeutics, Inc.

Galectin Therapeutics (OTC: GALT) is developing promising carbohydrate-based therapies for fibrotic liver disease and cancer based on the Company’s unique understanding of ga...

Jewish Hospital and University of Louisville

Jewish Hospital, a part of KentuckyOne Health, is an internationally renowned high-tech tertiary referral center developing leading-edge advancements in hand and microsurge...

Thermedical

Based in Somerville, Mass., Thermedical is a privately held company founded by Michael G. Curley, Ph.D., and Patrick S. Hamilton, Ph.D. Under multiple National Institutes...

Transgene SA

Transgene (NYSE-Euronext: TNG), a member of the Institut Mérieux Group, is a biopharmaceutical company. It creates, develops and manufactures targeted immunotherapeutics for th...

Hepregen Corporation

Hepregen Corporation is the undisputed leader in innovating unique and proprietary bioengineered micro- liver platforms for use in environmental testing, preventive care, and phar...

The Alpha-1 Project

Mission statement: The Alpha-1 Project will work with patients, academia, pharmaceutical and biotech companies, and public health organizations in the relentless pursuit of cures...

YES

YES is a grassroots organization that provides cancer patients with support, resources, options, education and hope in their fight against liver tumors. It is made up of sur...

Clinical Trials [ 1302 Associated Clinical Trials listed on BioPortfolio]

The Effect of Exercise Intervention on Insulin Resistance in Non-alcoholic Fatty Liver Disease (NAFLD)

This project examines the effects of a 4 month structured exercise intervention program in patients with non-alcoholic fatty liver disease (NAFLD). We will examine changes in total and dep...

A Multiple Dose Study of MK-5172 in Hepatitis C-Infected Participants (MK-5172-010 AM1)

This study will compare hepatic pharmacokinetics (PK) derived from liver tissue to plasma PK after administration of MK-5172 to participants with chronic hepatitis C virus (HCV) infection....

Dose Escalation Study Combining Oral Capecitabine (Xeloda) and Radiotherapy for Patients With Unresectable Liver or Cholangiocarcinoma

Our long-term working hypothesis is that if 3-D radiation is combined with the effect of capecitabine one hopes to see improved and durable tumor response and survival with acceptable toxi...

HRN 004- Peginterferon a-2a Plus Ribavirin for Chronic Hepatitis C Infection in HIV Infected Persons Who Have Failed to Achieve a Sustained Virologic Response Following Previous Interferon Therapy

Objectives: Primary To evaluate the safety, tolerability, and efficacy of Peginterferon a-2a plus Ribavirin for the treatment of chronic hepatitis C (CHC) infection in persons co-infected...

Study for the Treatment of Significant Steatosis With Xenical Followed by Treatment of Hepatitis C With Pegasys/Copegus

This is a prospective, multi-center, randomized, placebo-controlled trial in subjects with histological evidence of > 33% hepatic steatosis or nonalcoholic steatohepatitis (NASH) and chron...

Lactate Metabolism Study in HIV Infected Persons

Lactic acidosis is a potentially life-threatening disease associated with the treatment of chronic HIV infection. Although acidosis is rare, hyperlactatemia is common and may have long ter...

Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combination With Chemotherapy With/Without Bevacizumab for Hepatic Metastases From Colorectal Cancer

The purpose of this study is to determine whether the addition of bevacizumab, to hepatic arterial therapy with floxuridine (FUDR) and dexamethasone (Dex) (regional chemotherapy), and eith...

Acute Normovolemic Hemodilution Versus Standard Intraoperative Management in Patients Having Hepatic Resection and Pancreaticoduodenectomy

With a major liver or pancreas operation, there is a chance that one will require a transfusion of blood products (either red blood cells or plasma). This may be necessary during the oper...

Evaluation of cccDNA and Total HBV DNA Kinetics in Lymphocytes, Total Blood and Serum in Chronic Hepatitis B Patients Treated With Adefovir Dipivoxil and Peg Interferon Alpha 2a

Serum HBV DNA is a referent but insufficient marker of therapeutic follow-up in chronic hepatitis B treatment. Intra hepatic cccDNA disappearance reflects HBV eradication in the liver....

A Study to Evaluate the Safety and Efficacy of FK506E (MR4) in Patients Undergoing Primary Liver Transplantation.

To evaluate and to compare efficacy and safety of a dual regimen with oral modified release tacrolimus FK506E (MR4) / steroids versus a dual regimen with oral tacrolimus FK506 / steroids i...

PubMed Articles [ 8645 Associated PubMed Articles listed on BioPortfolio]

Sofosbuvir for previously untreated chronic hepatitis C infection.

In phase 2 trials, the nucleotide polymerase inhibitor sofosbuvir was effective in previously untreated patients with chronic hepatitis C virus (HCV) genotype 1, 2, or 3 infection.

Endocoil placement after endoscopic ultrasound-guided biliary drainage may prevent a bile leak.

To further reduce the risk of bleeding or bile leakage.

Do MDR1 and SLCO1B1 Polymorphisms Influence the Therapeutic Response to Atorvastatin? A Study on a Cohort of Egyptian Patients with Hypercholesterolemia.

BACKGROUND: Statins are among the most prescribed drugs worldwide to reduce the risk of cardiovascular events. Interindividual variability in drug response is a major clinical problem and is of concer...

Unexpectedly low variation in liver ischemia preconditioning study.

Assessment of anti-mutagenic, anti-histopathologic and antioxidant capacities of Egyptian bee pollen and propolis extracts.

Bee pollen and propolis are popular, traditional health foods. The objective of the current study was to investigate the anti-mutagenic, anti-histopathologic and antioxidant effects among water extrac...

Intraoperative ICG plasma disappearance rate helps to predict absence of early postoperative complications after orthotopic liver transplantation.

Early postoperative complications after orthotopic liver transplantation (OLT) are a common problem in intensive care medicine. Adequate assessment of initial graft function remains difficult, however...

Primary Budd-Chiari syndrome in a 3-year-old boy with homozygous factor V Leiden G1691A mutation.

Budd-Chiari syndrome (BCS) is an uncommon disorder characterized by obstruction of hepatic venous outflow. The primary BCS is a rare disease with an incidence about 0.2 per million inhabitants per yea...

High-Molecular-Weight Poly-Gamma-Glutamate Protects Against Hypertriglyceridemic Effects of a High-Fructose Diet in Rat.

We studied the effects of 2 different dosages of highmolecular- weight poly-gamma-glutamic acid (hm gamma-PGA) derived from Bacillus subtilis chungkookjang on lipid metabolism in a high-fructose diet-...

Effect of extruded linseed supplementation on blood metabolic profile and milk performance of Saanen goats.

This study assessed the effects of dietary supplementation with extruded linseed on milk yield and composition, milk fatty acid (FA) profile and renal and hepatic metabolism of grazing goats in mid-la...

Current and future therapies for hepatitis C virus infection.

Medical and Biotech [MESH] Definitions

Adenine Nucleotide Translocator 3

A subtype of mitochondrial ADP, ATP translocase found primarily in the LIVER.

Hypoalbuminemia

A condition in which albumin level in blood (SERUM ALBUMIN) is below the normal range. Hypoalbuminemia may be due to decreased hepatic albumin synthesis, increased albumin catabolism, altered albumin distribution, or albumin loss through the urine (ALBUMINURIA).

Streptococcus Intermedius

A species of gram-positive bacteria in the STREPTOCOCCUS MILLERI GROUP. It is commonly found in the oropharynx flora and has a proclivity for abscess formation, most characteristically in the CENTRAL NERVOUS SYSTEM and LIVER.

Mastocytosis, Systemic

A group of disorders caused by the abnormal proliferation of MAST CELLS in a variety of extracutaneous tissues including bone marrow, liver, spleen, lymph nodes, and gastrointestinal tract. Systemic mastocytosis is commonly seen in adults. These diseases are categorized on the basis of clinical features, pathologic findings, and prognosis.

Receptor, Epha1

The founding member of the EPH FAMILY RECEPTORS. It was first cloned from an erythropoietin-producing human hepatocellular carcinoma cell line and is highly conserved among many mammalian species. Overproduction of the EphA1 receptor is associated with tumors and tumor cells of epithelial origin. It is also expressed at high levels in LIVER; LUNG; and KIDNEY; which is in contrast to many other members of the Eph receptor that are found primarily in tissues of the nervous system.

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