HIVAssociated Dementia - Biotech, Pharma and Life Science Channel
PubMed Articles
Responders versus nonresponders in a dementia study of the oldest old: the 90+ study.
Because of difficulties in finding, recruiting, and diagnosing dementia in the oldest old (ages ≥90 years), most incidence studies include few very elderly persons, and little is known about the cha...
20-Year prevalence projections for dementia and impact of preventive policy about risk factors.
Incidence of dementia increases sharply with age and, because of the increase in life expectancy, the number of dementia cases is expected to rise dramatically over time. Some studies suggest that con...
Missing data is a very common problem in medical and social studies, especially when data are collected longitudinally. It is a challenging problem to utilize observed data effectively. Many papers on...
Obesity as a risk factor for poor neurocognitive outcomes in older adults with heart failure.
Heart failure (HF) has reached epidemic proportions and is a significant contributor to poor outcomes. HF is an established risk factor for Alzheimer's disease, vascular dementia, and abnormalities on...
This study provides evidence that a number of frailty-related characteristics (older age, de novo admission to long-term care (LTC), comorbidities [Charlson Index, osteoporosis, osteoporosis risk fact...
A family history of dementia is associated with an increased risk of developing Alzheimer's disease (AD) late in life (LOAD). This study marked the first attempt to assess the familial contribution to...
Speech and orofacial apraxias in Alzheimer's disease.
ABSTRACT Background: Alzheimer's disease (AD) affects not only memory but also other cognitive functions, such as orientation, language, praxis, attention, visual perception, or executive function. Mo...
HIV-Associated Neurocognitive Disorders: Perspective on Management Strategies.
Potent combination antiretroviral therapy (ART) has resulted in dramatic improvements in AIDS-associated morbidity and mortality. Although combination ART has resulted in a significant reduction in HI...
People over the age of 90 years-the oldest old-are the fastest growing sector of the population. A substantial proportion of these individuals are affected by dementia, with major implications for the...
ABSTRACT Background: Good medication adherence is the cornerstone of therapeutic success. Alzheimer's disease (AD) is the most common type of dementia and most patients are old and on multiple drugs,...
News Articles
New Charity Foundation Will Give Specialized Care for Individuals with Alzheimer’s
The Memory Loss Foundation has launched its official charity to help improve the lives of seniors living with dementia. Toronto, ON (PRWEB) June 19, 2013 Dementia/Alzheimer’s has plagued many of ou...
Apomorphine May Protect Against Parkinson's Dementia
Apomorphine may represent a novel therapeutic agent to reduce the burden of cognitive impairment in Parkinson's disease, new research hints. Medscape Medical News
100 practices use CantabMobile
CantabMobile is an app to detect early signs of dementia in older patients.
Storytelling program helps change medical students' perspectives on dementia
Treating patients with dementia can be viewed as a difficult task for doctors, but Penn State College of Medicine researchers say that storytelling may be one way to improve medical students' percepti...
Study shows brain abnormalities in MTBI patients closely resemble Alzheimer's dementia
The distribution of white matter brain abnormalities in some patients after mild traumatic brain injury (MTBI) closely resembles that found in early Alzheimer's dementia, according to a new study publ...
Concussion patients show Alzheimer's-like brain abnormalities
The distribution of white matter brain abnormalities in some patients after mild traumatic brain injury (MTBI) closely resembles that found in early Alzheimer's dementia, according to a new study publ...
Storytelling program helps change medical students' perspectives on dementia
(Penn State) Treating patients with dementia can be viewed as a difficult task for doctors, but Penn State College of Medicine researchers say that storytelling may be one way to improve medical stude...
Building resilience through HeartMath
Resilience is an important quality for patients battling infections and illnesses, but in order for their care to be provided, staff need resilience against all the stresses, strains and pressures o...
"Memory Vacation" is Summer Getaway for Those with Alzheimer's and their Families
SEATTLE, June 17, 2013 /PRNewswire/ -- Everyone loves a summer break and people with Alzheimer's disease are no different. While taking a trip may not be feasible for many with dementia, another kind...
Berkshire gets its first Admiral nurse for dementia
A specialist dementia nurse service has been established in West Berkshire with special expertise in younger patients with the condition.
Events
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Companies
HopeHealth, formerly known as Hospice & Palliative Care of Cape Cod, has been enhancing the quality of life for people experiencing serious illness and loss for more than thirty y...
Avid Radiopharmaceuticals, Inc.
Avid Radiopharmaceuticals is a leader in the development of molecular imaging products with the potential for earlier and more effective detection, diagnosis and monitoring of maj...
For more than a decade, Potomac Homes has made it possible for those with Alzheimerâs disease or dementia-related illnesses to enjoy the benefits of full-time professional ca...
Senior Resource Group, LLC (SRG) has been a leader in providing distinctive retirement living since 1988. SRG develops, owns and operates independent living, assisted living and A...
Homewatch CareGivers International
Homewatch CareGivers International provides home care and personal assistance that individuals who are aging, disabled and rehabilitating need to remain in their homes. Since its...
Emeritus Corporation is a national provider of assisted living and Alzheimer's and related dementia care services to seniors. Emeritus is one of the largest and most experienced o...
Janssen Alzheimer Immunotherapy
Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...
Clinical Trials
Music Therapy in Methodist Homes: a Study Investigating the Impact of a Music Therapy Programme
The study is a cluster randomised control trial, which aims to investigate the effectiveness of music therapy in minimising Behavioural and Psychological Symptoms of Dementia (BPSD) in old...
An Efficacy and Safety Study of Galantamine for the Treatment of Patients With Alzheimer's Disease
The purpose of this study is to evaluate the efficacy and safety of two fixed doses (16mg/day and 24mg/day) of galantamine (a drug for treating dementia) versus placebo for the treatment o...
Deep brain stimulation has been developed as a substitute for the classical lesioning methods previously used in stereotactic and functional neurosurgery. Recent, anecdotal cases reports...
Donepezil Treatment of Psychotic Symptoms in Dementia Patients
Conventional psychotropic medications may be used to treat behavioral disturbances and psychotic symptoms in patients with dementia and they are the drugs of choice for treating delusions...
Objectives: The objective of this study will be to determine the safety, tolerability, drug blood levels, and efficacy of each of three doses of NS 2330 (Tesofensine) given once daily com...
Cognitive Training in the Elderly
Background: The aging of the population has lead to a significant increase in the number of older people suffering from cognitive impairment and dementia. The present lack of effective dr...
Double Blind Trial of DC Polarization in FTD
This project is designed to test how direct current (DC) electrical polarization of the brain affects language and behavior in patients with frontotemporal dementia (FTD). FTD is the secon...
Relationship of Dopamine to Cognitive Function in Parkinson's Disease
This study will examine how the brain chemical dopamine affects memory, reasoning, and other thought processes in people with Parkinson's disease with and without dementia and in healthy c...
Treatment Study of Frontotemporal Dementia
Objectives. The proposed clinical study has two goals: First, to assess the efficacy of a central nervous system stimulant and an atypical antipsychotic in treating the behavioral symptom...
Brain Imaging in Alzheimer's Disease
The purpose of this study is to use brain imaging technology to examine the role of certain brain chemicals in individuals with Alzheimer's disease (AD) and in healthy volunteers. Cogniti...
Videos
HIV-associated Neurocognitive Impairment
Igor Grant, Univ of California, San Diego, discusses the high prevalence of Neurocognitive Impairment which is found in the HIV positive population. Intervie...
Medical and Biotech [MESH] Definitions
Leukoaraiosis
Non-specific white matter changes in the BRAIN, often seen after age 65. Changes include loss of AXONS; MYELIN pallor, GLIOSIS, loss of ependymal cells, and enlarged perivascular spaces. Leukoaraiosis is a risk factor for DEMENTIA and CEREBROVASCULAR DISORDERS.
Marchiafava-bignami Disease
A neurodegenerative condition that is characterized by demyelination or necrosis of the CORPUS CALLOSUM. Symptoms include DEPRESSION; PARANOIA; DEMENTIA; SEIZURES; and ATAXIA which can progress to COMA and death in a few months. Marchiafava-Bignami syndrome is seen often in alcoholics but has been found in non-alcoholics as well.
Diffuse Neurofibrillary Tangles With Calcification
A form of presenile DEMENTIA characterized by cortical dementia, NEUROFIBRILLARY TANGLES without SENILE PLAQUES, Fahr's type CALCINOSIS, and ATROPHY in frontotemporal or TEMPORAL LOBE.
Frontotemporal Lobar Degeneration
Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Multiple subtypes or forms are recognized based on presence or absence of TAU PROTEIN inclusions. FTLD includes three clinical syndromes: FRONTOTEMPORAL DEMENTIA, semantic dementia, and PRIMARY PROGRESSIVE NONFLUENT APHASIA.
Primary Progressive Nonfluent Aphasia
A form of frontotemporal lobar degeneration and a progressive form of dementia characterized by motor speech impairment and AGRAMMATISM, with relative sparing of single word comprehension and semantic memory.
