Host Defense Mechanisms - Biotech, Pharma and Life Science Channel

16:26 EDT 2nd August 2015 | BioPortfolio

PubMed Articles [10380 Associated PubMed Articles listed on BioPortfolio]

Enhanced Antifungal Activity by Ab-Modified Amphotericin B-Loaded Nanoparticles Using a pH-Responsive Block Copolymer.

Fungal infections are an important cause of morbidity and mortality in immunocompromised patients. Amphotericin B (AMB), with broad-spectrum antifungal activity, has long been recognized as a powerful...

Synthesis of Mn3O 4-Based Aerogels and Their Lithium-Storage Abilities.

Mn3O4 aerogels and their graphene nanosheet (GN) composite aerogels were synthesized by a simple supercritical-ethanol process. In the process, supercritical ethanol acted as a reductant to reduce gra...

Review of beetle forewing structures and their biomimetic applications in China: (II) On the three-dimensional structure, modeling and imitation.

This paper reviews the research progress made in China regarding the microstructure of the forewing trabeculae, their anti-peeling and anti-collisional mechanical properties, the three-dimensional (3D...

Bone-like apatite coating on functionalized poly(etheretherketone) surface via tailored silanization layers technique.

Poly(etheretherketone) (PEEK) is a rigid semi-crystalline polymer with outstanding mechanical properties, bone-like stiffness and suitable biocompatibility that has attracted much interest as a biomat...

Synthesis and characterization of silane coated magnetic nanoparticles/glycidylmethacrylate-grafted-maleated cyclodextrin composite hydrogel as a drug carrier for the controlled delivery of 5-fluorouracil.

A novel drug delivery system (DDS), 3-methacryloxypropyl trimethoxy silane coated magnetic nanoparticles polymerized with glycidylmethacrylate-grafted-maleated cyclodextrin (MPTMS-MNP-poly-(GMA-g-MACD...

Susceptibility to corrosion of laser welding composite arch wire in artificial saliva of salivary amylase and pancreatic amylase.

In this study, laser-welded composite arch wire (CAW) with a copper interlayer was exposed to artificial saliva containing salivary amylase or pancreatic amylase, and the resultant corrosion behavior ...

Bio-functional nano-coatings on metallic biomaterials.

Metals and their alloys have been widely used in all aspects of science, engineering and medicine. Metals in biomedical devices are used due to their inertness and structural functions. They are gener...

Role of indoleamine 2,3-dioxygenase in health and disease.

IDO1 (indoleamine 2,3-dioxygenase 1) is a member of a unique class of mammalian haem dioxygenases that catalyse the oxidative catabolism of the least-abundant essential amino acid, L-Trp (L-tryptophan...

Mineralocorticoid receptor blockade prevents vascular remodelling in a rodent model of type 2 diabetes mellitus.

Mineralocorticoid receptors (MRs), which are activated by mineralocorticoids and glucocorticoids, actively participate in mechanisms that affect the structure and function of blood vessels. Although e...

A breakdown in communication? Understanding the effects of aging on the human small intestine epithelium.

In the intestine, a single layer of epithelial cells sealed together at their apical surfaces by tight junctions helps to prevent the luminal commensal and pathogenic micro-organisms and their toxins ...

News Articles [2703 Associated News Articles listed on BioPortfolio]

Correct Auto-Correct and Clarify the Unclear with reTXT Messaging App

(PRWEB) August 01, 2015 “ reTXT ” was featured on NewsWatch as part of its monthly AppWatch, which takes a look at the lat...

Pharmaceutical Research: A Role for Low Density Lipoprotein Receptor-Related Protein 1 in the Cellular Uptake of Tissue Plasminogen Activator in the Lungs

Type: Original PaperPurposeTo gain knowledge of lung clearance mechanisms of inhaled tissue plasminogen activator (tPA).MethodsUsing an in vivo mouse model and ex vivo murine whole organ cell suspensi...

Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth

Romagnolo and colleagues report that Atg7 deficiency has a tumour-suppressive role in the intestinal epithelium, by inducing a microbiome-influenced immune response and inhibiting tumour growth throug...

This week on MedHeads: Cerner taking on the DoD’s EHR contract and a look at cancer drug prices

Here's a closer look at Cerner and its Defense Healthcare Management System Modernization contract as well as some conversation about cancer drug prices.

IDEXX Laboratories to Host 2015 Analyst Day

WESTBROOK, Maine, July 31, 2015 /PRNewswire/ -- IDEXX Laboratories, Inc. (NASDAQ: IDXX) will host its 2015 Analyst Day on August 5-6, 2015 at its corporate headquarters in Westbrook, Maine. A liv...

Understanding images: A genetic framework in legumes controls infection of nodules

The soil environment harbors a diverse range of bacteria, many of which could potentially be detrimental if they are able to gain entry to plant tissues. We are interested in determining how the host ...

Ocata Therapeutics to Host Conference Call and Webcast to Provide Corporate Update for the Second Quarter of 2015

Call Scheduled for Thursday, August 6, 2015 at 4:30 P.M. Ocata Therapeutics, Inc. (NASDAQ: OCAT), a leader in the field of Regenerative Ophthalmology™, announced today that ...

DirectEmployers and Easter Seals to Host Networking Luncheon and Virtual Impact Forum

INDIANAPOLIS, July 31, 2015 (GLOBE NEWSWIRE) -- On Tuesday, August 4, DirectEmployers Association will be featured at the inaugural Easter Seals Impact Forum, a free

Beasley Broadcast Group to Report 2015 Second Quarter Results and Host Webcast on August 7

NAPLES, Fla., July 31, 2015 (GLOBE NEWSWIRE) -- Beasley Broadcast Group, Inc. (Nasdaq:BBGI), a large- and mid-size market radio broadcaster, will release its fiscal 2015 second quarter financial ...

Arena Pharmaceuticals, Inc. To Host Second Quarter 2015 Financial Results And Corporate Update Conference Call And Webcast On Wednesday, August 5

SAN DIEGO, July 30, 2015 /PRNewswire/ --Arena Pharmaceuticals, Inc. (NASDAQ: ARNA) today announcedthat it will host a conference call and webcast at 5:00 p.m. Eastern Time (2:00 p.m. Pacific Time) on ...

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Companies [208 Associated Companies listed on BioPortfolio]

PeterGreenlaw.com

Peter Greenlaw is a renowned health and wellness expert, researcher, speaker and co-author of "Your Third Brain: The Revolutionary Discovery to Achieve Optimal Health," "TDOS Synd...

Arlington Capital Partners

Arlington Capital Partners is a Washington, D.C.-based private equity firm with $1.5 billion of committed capital focused on middle market investment opportunities in growth indus...

airweave holdings inc.

About IMG AcademyIMG Academy is the world’s largest and most advanced multi-sport training and educational institution. IMG Academy helps countless youth, adult, colle...

Cannabis Creative Conference

The two-day Cannabis Creative Conference will host more than 600 business professionals, and more than 60 speakers will hold forums and panels to educate businesses about the emer...

EAG, Inc.

EAG, Inc. is the world’s leading, fully integrated, independent laboratory network providing services to a very wide range of industries. EAG currently has three core divisio...

Exostar and Taigle

Exostar powers secure business-to-business information sharing, collaboration and business process integration throughout the value chain. Exostar supports the complex trading nee...

Blank Rome LLP

With more than 500 attorneys serving clients around the globe, Blank Rome is an international law firm representing businesses and organizations ranging from Fortune 500 companies...

Exovita Biosciences, Inc.

New Mexico-based Exovita Biosciences is working to harness the body’s own defenses against cancer. Exovita is developing the next generation of biological cancer therapeutics...

Acceleron Pharma & Celgene Corporation

Acceleron is a clinical stage biopharmaceutical company focused on the discovery, development and commercialization of novel therapeutic candidates that regulate cellular growth a...

Allele Biotechnology & Pharmaceuticals, Inc.

Allele Biotechnology and Pharmaceuticals, Inc. is a private, San Diego-based company that explores the mechanisms of biological processes to develop technologies and products for ...

Clinical Trials [1185 Associated Clinical Trials listed on BioPortfolio]

Ixazomib Citrate in Treating Patients With Chronic Graft-versus-Host Disease

This phase II trial studies how well ixazomib citrate works in treating patients with chronic graft-versus-host disease. Chronic graft-versus-host disease is a complication of a donor bone...

Impact of JuicePlus+ on the Health Status of an Overweight Stressed Population

The purpose of this study is to determine if a dried fruit and vegetable supplement (Juice Plus+) can alter the gut microbiome and improve gut permeability and inflammatory levels in an ob...

Transdermal Patch to Monitor Inflammatory Biomarkers of GVHD

The aim of this study is to measure local inflammatory responses in patients undergoing an allogeneic stem cell transplant and attempt to define any set of biomarkers that are significantl...

Efficacy and Mechanisms of Acupuncture for Patients With Advanced Pancreatic Cancer Pain

This study compares the effect of acupuncture and placebo acupuncture on advanced pancreatic cancer pain and then investigates its potential mechanism of peripheral blood.

Nutrition and Life QUality Patients With Head and Neck Cancers

Malnutrition is currently a major factor of morbidity and mortality, which poses a major public health problem in developing countries but also, albeit to a lesser degree and for different...

Relationship Between Obesity and Periodontal Disease

Obesity is an epidemic with increasing prevalence in the Asia Pacific region. The first Malaysian national estimate in 1996 of obesity was 5.8%. A systematic review reported a marked incre...

Personalized Immunotherapeutics for Antibiotic-resistant Infection

M. A. suffers from hypogammaglobulinemia that has been complicated by refractory Mycoplasma hominis septic arthritis. He has been receiving the antibiotic valnemulin under Emergency Invest...

Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa

This phase I trial studies the side effects and best dose of zoledronic acid given after genetically modified donor stem cell transplant in treating younger patients with hematologic malig...

Emotional Processing and Oxytocin Mechanisms in Premenstrual Dysphoric Disorder: A Pilot Study

This research study will look at differences among women with severe premenstrual mood symptoms. One goal of this study is to look at how the brains of two groups of these women respond to...

A Phase 2 Study to Evaluate Effects of VX-661/Ivacaftor on Lung and Extrapulmonary Systems in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

To evaluate the clinical mechanisms of action in lung and extrapulmonary systems of VX-661 in combination with ivacaftor (IVA) (VX-661/IVA) in subjects with cystic fibrosis (CF) who are ho...

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Medical and Biotech [MESH] Definitions

The mechanisms by which a cell becomes internalized in another. The host cell may engulf another as do PHAGOCYTIC CELLS, or the host cell may be invaded by another cell (ENTOSIS), or internalization processes may involve the cooperation of both the host cell and the cell being internalized. Viable cells may remain in non-phagocytic cells (EMPERIPOLESIS), undergo cell division, pass through and then out of the host cell (TRANSCELLULAR CELL MIGRATION), or trigger APOPTOSIS of the invaded cell.

Unconscious process used by an individual or a group of individuals in order to cope with impulses, feelings or ideas which are not acceptable at their conscious level; various types include reaction formation, projection and self reversal.

Processes that translocate macromolecules across the cell envelope of gram negative bacteria, often directly into the host. These effectors modulate the defense response and thereby facilitate survival of the pathogen.

A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.

Defense mechanisms involving approach and avoidance responses to threatening stimuli. The sensitizing process involves intellectualization in approaching or controlling the stimulus whereas repression involves unconscious denial in avoiding the stimulus.


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