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Host Defense Mechanisms - Biotech, Pharma and Life Science Channel

15:50 EDT 29th August 2016 | BioPortfolio

PubMed Articles [11024 Associated PubMed Articles listed on BioPortfolio]

Is Neurotoxicity of Metallic Nanoparticles the Cascades of Oxidative Stress?

With the rapid development of nanotechnology, metallic (metal or metal oxide) nanoparticles (NPs) are widely used in many fields such as cosmetics, the food and building industries, and bio-medical in...

Contributions of p38 and ERK to the antinociceptive effects of TGF-β1 in chronic constriction injury-induced neuropathic rats.

Transforming growth factor-βs (TGF-βs) are a group of multifunctional proteins that have neuroprotective roles in various experimental models. We previously reported that intrathecal (i.t.) injectio...

The Role of Annealing Process in Ag-Based BaSnO3 Multilayer Thin Films.

The BaSnO3/Ag/BaSnO3 multilayer structure was designed and fabricated on a quartz glass by magnetron sputtering, followed by an annealing process at a temperature from 150 to 750 °C in air. In this ...

Role of PTHrP(1-34) Pulse Frequency Versus Pulse Duration to Enhance Mesenchymal Stromal Cell Chondrogenesis.

Generation of phenotypically stable, articular chondrocytes from mesenchymal stromal cells (MSCs) is still an unaccomplished task, with formation of abundant, hyaline extracellular matrix, and avoidan...

A multi-subband Monte Carlo study on dominance of scattering mechanisms over carrier transport in sub-10-nm Si nanowire FETs.

Dominance of various scattering mechanisms in determination of the carrier mobility is examined for silicon (Si) nanowires of sub-10-nm cross-sections. With a focus on p-type channels, the steady-stat...

Recent progress on the genetics and molecular breeding of brown planthopper resistance in rice.

Brown planthopper (BPH) is the most devastating pest of rice. Host-plant resistance is the most desirable and economic strategy in the management of BPH. To date, 29 major BPH resistance genes have be...

Multi-responsive magnetic microsphere of poly(N-isopropylacrylamide)/carboxymethylchitosan hydrogel for drug controlled release.

Multi-responsive composite microspheres were synthesized via an in situ free radical polymerization of thermo-responsive poly(N-isopropylacrylamide) (poly(NIPAAm)) in the presence of carboxymethylchit...

Probing inclusion complexes of cyclodextrins with amino acids by physicochemical approach.

Formations of host-guest inclusion complexes of two natural amino acids, viz., l-Leucine and l-Isoleucine as guests with α and β-cyclodextrins have been investigated which include diverse applicatio...

Chitosan and oligochitosan enhance ginger (Zingiber officinale Roscoe) resistance to rhizome rot caused by Fusarium oxysporum in storage.

The ability of chitosan and oligochitosan to enhance ginger (Zingiber officinale) resistance to rhizome rot caused by Fusarium oxysporum in storage was investigated. Both chitosan and oligochitosan at...

Adsorptive removal of Lead from water by the effective and reusable magnetic cellulose nanocomposite beads entrapping activated bentonite.

Many efforts have been driven to decontaminate the drinking water, and the development of efficient adsorbents with the advantages of cost-effectiveness and operating convenience for the removal of Pb...

News Articles [2632 Associated News Articles listed on BioPortfolio]

Lymphoma Research Foundation To Host Annual Gala in September During Blood Cancer Awareness Month

Evening of Incredible Inspiration Set to Return to Mandarin Oriental in New York City New York, NY (PRWEB) August 29, 2016 The Lymphoma Research Foundation (LRF) – the nation’s largest non-profit...

American Telemedicine Association to Host Fall Forum Focused on Telehealth Innovation and Rapidly Changing Industry Landscape

Political Icons James Carville and Mary Matalin to Keynote Alongside Telemedicine Industry Experts at New Orleans Telehealth Forum WASHINGTON, DC (PRWEB) August 29, 2016 The American Telemedicine Ass...

LIVE 9:55 – 12:00 8/29 UNDERSTANDING MECHANISMS OF ACTION @IMMUNO-ONCOLOGY SUMMIT – AUGUST 29-30, 2016 | Marriott Long Wharf Hotel – Boston, MA

LIVE 9:55 – 12:00 8/29 UNDERSTANDING MECHANISMS OF ACTION @IMMUNO-ONCOLOGY SUMMIT – AUGUST 29-30, 2016 | Marriott Long Wharf Hotel – Boston, MA http://www.immuno-oncologysummit.com/upl...

MassRoots and Flowhub Release Integration Update, to Host Facebook Live Q&A at 3:30pm EDT Today

DENVER, Aug. 29, 2016 /PRNewswire/ -- MassRoots, Inc. (OTCQB:MSRT) and Flowhub, a point-of-sale and cultivation management platform focused on the cannabis industry, are pleased to provide an update o...

Goodbye E. coli, Hello Vmax?

Scientists from Synthetic Genomics (SGI) say they have developed and engineered Vibrio natriegens into a next-generation biotechnology host organism VmaxTM. Looking to accelerate the pace of discove...

Teva to Host Generic Medicines Business Overview on September 9, 2016

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Synthetic Genomics team engineers Vmax™, an advantaged next-generation host organism for a wide range of biotechnology applications

LA JOLLA, Calif., Aug. 29, 2016 /PRNewswire/ -- Researchers from Synthetic Genomics, Inc. (SGI) announced today the development and extensive engineering of Vibrio natriegens into a next-generation bi...

Paralyzed Veterans of America Educates Hundreds of Spinal Cord Injury and Disease Health Care Professionals at 6th Annual Summit & EXPO

WASHINGTON, Aug. 29, 2016 /PRNewswire/ -- Beginning tomorrow, Paralyzed Veterans of America (Paralyzed Veterans) will host nearly 840 health care professionals at its 2016 Summit + EXPO August 30...

Researchers unmaks lobbyists' model legislation

Since 2005, about two dozen states have created "Stand Your Ground" laws authorizing deadly force in self-defense. And nearly all of those laws have similar language.

Melanoma—mechanisms of BRAF-inhibitor resistance deciphered

BRAF mutation occurs in between 40% and 50% of metastasising melanomas (skin cancers), boosting tumour growth. Patients with metastasising melanomas and who display BRAF mutation can be treated with a...

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Companies [223 Associated Companies listed on BioPortfolio]

Vedanta Biosciences

Vedanta Biosciences, a privately held company, was co-founded by PureTech Ventures and a group of world renowned experts in immunology and microbiology. Vedanta Biosciences' mission is to develop a no...

XenoPort

We are a biopharmaceutical company focused on developing a portfolio of internally discovered product candidates for the potential treatment of central nervous system (CNS) disorders. We also have a p...

Unity Biotechnology

Unity Biotechnology is designing therapeutics that prevent, halt or reverse numerous diseases of aging. The Company is targeting biological mechanisms that unify many afflictions,...

CMMI Institute

CMMI Institute (CMMIinstitute.com) is the organization behind Capability Maturity Model Integration (CMMI®), the globally adopted capability improvement framework that g...

Telephus Medical LLC

Telephus Medical, located in San Diego, California, is developing a suite of monoclonal antibody products designed to neutralize key staphylococcal enzymes used to attach to host ...

Armor

The leader in active cyber defense, Armor offers customer-centric security outcomes for retail and eCommerce enterprises, healthcare organizations, payment leaders and financial i...

Histide AG

Histide™ is a biotech intellectual property platform company pioneering a new class of nonmutagenic extracellular therapeutic agents called Cell Recoding Molecules™ (CRM...

Lieber Institute for Brain Development

The mission of the Lieber Institute for Brain Development and the Maltz Research Laboratories is to translate the understanding of basic genetic and molecular mechanisms of schizo...

Cambrian Innovation

Cambrian Innovation is a leader in developing biotechnology solutions that extract energy from water. Spun out of MIT in 2006, Cambrian has scaled and validated its proprie...

NantKwest, Inc.

NantKwest (Nasdaq:NK) is a pioneering, next generation, clinical-stage immunotherapy company focused on harnessing the unique power of our immune system using natural killer (NK) ...

Clinical Trials [1552 Associated Clinical Trials listed on BioPortfolio]

Ablative Fractional Laser for Sclerotic GVHD-Associated Joint Contractures

Graft versus host disease (GVHD) is a common complication of allogeneic stem cell transplant.Chronic GVHD is characterized by skin thickening and tightening. Advanced sclerosis can lead to...

Evaluation of Inter-patient Variability Size of the Nasal Cavity, Based on CT Scans

This study is part of the french research program ANR NEMRO "MICROROBOTIC NASAL ENDOSCOPY BY OPTICAL COHERENCE TOMOGRAPHY: IMPACT OF SMELL DEFICIENCY ON NEURODEGENERATIVE DISEASES." Recent...

A 12-weeks Study to Evaluate Sulforaphane in Treatment of Autism Spectrum Disorder

In this proposed study, the investigators will evaluate the the efficacy, safety and related mechanism of sulforaphane in treatment of autism spectrum disorder (ASD). The study will recrui...

Is There Any Correlation Between Plasmatic Zonulin and Expression of Intestinal Tight Junction Proteins in IBS Patients?

Increased intestinal permeability is one of the main pathophysiological mechanisms involved in irritable bowel syndrome. The expression of some intestinal tight junction proteins is decrea...

Tacrolimus, Bortezomib, & Thymoglobulin in Preventing Low Toxicity GVHD in Donor Blood Stem Cell Transplant Patients

This phase II trial studies how well tacrolimus, bortezomib, and anti-thymocyte globulin (thymoglobulin) work in preventing low toxicity graft versus host disease (GVHD) in patients with b...

Cyclophosphamide Versus Anti-thymocyte Globulin for GVHD Prophylaxis After RIC Allo-SCT

The study is designed as a two arm randomized Phase II, multicenter trial comparing cyclophosphamide to anti-thymocyte globulin for Graft-versus-Host Disease (GVHD) prophylaxis in patients...

Investigating Gains in Neurocognition in an Intervention Trial of Exercise

This randomized control trial will examine whether a 12 month monitored exercise intervention improves brain health in cognitively normal older adults. This trial will also address several...

Characterization of Immunosuppressive Signing of Cervical Cancer

Infection with Human Papillomavirus high-risk Human (HR-HPV) is the main factor of risk of cancer of the cervix. Recent studies show that cancers linked to infection with HR-HPV are associ...

The Clinical Research on the Relationship Between Depression and Gut Microbiota in TBI Patients

Microbiome studies may be highlighted as crucial in the development of depression for TBI patients. The microbiota-gut-brain connection may further provide an opportunity for microbiota ma...

Mechanisms of Diastolic Dysfunction Among Persons With HIV Compared With Non-HIV Control Subjects

In this study, investigators plan to test two potential mechanisms contributing to diastolic dysfunction among asymptomatic persons with HIV who are on cART. The first proposed mechanism i...

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Medical and Biotech [MESH] Definitions

The mechanisms by which a cell becomes internalized in another. The host cell may engulf another as do PHAGOCYTIC CELLS, or the host cell may be invaded by another cell (ENTOSIS), or internalization processes may involve the cooperation of both the host cell and the cell being internalized. Viable cells may remain in non-phagocytic cells (EMPERIPOLESIS), undergo cell division, pass through and then out of the host cell (TRANSCELLULAR CELL MIGRATION), or trigger APOPTOSIS of the invaded cell.

Unconscious process used by an individual or a group of individuals in order to cope with impulses, feelings or ideas which are not acceptable at their conscious level; various types include reaction formation, projection and self reversal.

Processes that translocate macromolecules across the cell envelope of gram negative bacteria, often directly into the host. These effectors modulate the defense response and thereby facilitate survival of the pathogen.

A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.

Defense mechanisms involving approach and avoidance responses to threatening stimuli. The sensitizing process involves intellectualization in approaching or controlling the stimulus whereas repression involves unconscious denial in avoiding the stimulus.

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