Host Defense Mechanisms - Biotech, Pharma and Life Science Channel

03:43 EDT 26th October 2014 | BioPortfolio

PubMed Articles [9639 Associated PubMed Articles listed on BioPortfolio]

In vitro genotoxicity of mycotoxins ochratoxin A and fumonisin B1 could be prevented by sodium copper chlorophyllin - Implication to their genotoxic mechanism.

The aim of this study was to investigate the possible protective effect of sodium copper chlorophyllin (CHL) against cytotoxicity and DNA damage induced by mycotoxins ochratoxin A (OTA) and fumonisin ...

Mouse models of rhinovirus infection and airways disease.

Mouse models are invaluable tools for gaining insight into host immunity during virus infection. Until recently, no practical mouse model for rhinovirus infection was available. Development of infecti...

Reverse genetics system for studying human rhinovirus infections.

Human rhinovirus (HRV) contains a 7.2 kb messenger-sense RNA genome which is the template for reproducing progeny viruses after it enters the cytoplasm of a host cell. Reverse genetics refers to the r...

Proteases of human rhinovirus: role in infection.

Human rhinoviruses (HRV) are the major etiological agents of the common cold and asthma exacerbations, with significant worldwide health and economic impact. Although large-scale population vaccinatio...

Peptidomics study of anthocyanin-rich juice of elderberry.

Biologically active peptides play a role in plant signaling and defense. Elderberry juice is known to contain a variety of anthocyanin compounds, a sub-set of polyphenols, which are responsible for th...

Resonance Rayleigh scattering method for determination of ethion using silver nanoparticles as probe.

A simple, novel and sensitive method was developed to determine ethion insecticide in water samples. This method was based on the interaction of ethion with silver nanoparticles (AgNPs) and quenching ...

A vapor response mechanism study of surface-modified single-walled carbon nanotubes coated chemiresistors and quartz crystal microbalance sensor arrays.

This paper compares the selectivity and discusses the response mechanisms of various surface-modified, single-walled carbon nanotube (SWCNT)-coated sensor arrays for the detection of volatile organic ...

β-Cyclodextrin coated CdSe/ZnS quantum dots for vanillin sensoring in food samples.

An optical sensor for vanillin in food samples using CdSe/ZnS quantum dots (QDs) modified with β-cyclodextrin (β-CD) was developed. This vanillin-sensor is based on the selective host-guest interact...

Analysis of human hyaluronan synthase gene transcriptional regulation and downstream hyaluronan cell surface receptor mobility in myofibroblast differentiation.

The ubiquitous extracellular glycosaminoglycan hyaluronan (HA) is a polymer composed of repeated disaccharide units of alternating D-glucuronic acid and D-N-acetylglucosamine residues linked via alter...

Isolation and purification of versican and analysis of versican proteolysis.

Versican is a widely distributed chondroitin sulfate proteoglycan that forms large complexes with the glycosaminoglycan hyaluronan (HA). As a consequence of HA binding to its receptor CD44 and interac...

News Articles [3009 Associated News Articles listed on BioPortfolio]

UPDATE 1-U.S. FDA issues emergency authorization for two new Ebola tests

NEW YORK, Oct 25 (Reuters) - Federal health regulators granted emergency authorization on Saturday for two new tests made by BioFire Defense that detect Ebola in humans, highlighting new steps by the ...

U.S. FDA issues emergency authorization for two new Ebola tests

WASHINGTON, Oct 25 (Reuters) - The U.S. Food and Drug Administration granted emergency authorization on Saturday for two new tests made by BioFire Defense that detect Ebola in humans.

COVERGIRL, Procter and Gamble’s Orgullosa and Publix Host a Power Meet-Up in Miami to Kick-off the Opening of Oprah’s the Life You Want Weekend; Photo Available on Business Wire's Website and AP PhotoExpress

TV Host and Chef Carla Hall, Singer Jessi Leon and Celebrity Fashion Stylist Irma Martinez participated in a Power Meet-Up of influential women, hosted by COVERGIRL, Olay, Orgullo...

An 'American Hustle': Why Don't CEO's Go to Jail?: The American Law Journal on the Philadelphia CNN-News Affiliate WFMZ-TV, Broadcast Now Online

Panel Examines Whistleblowers, False Claims Act & "Big Corporations Behaving Badly." Philadelphia, PA (PRWEB) October 24, 2014 In the wake of the Wall Street meltdown, banking fraud and...

Dicerna to Announce Third-Quarter 2014 Financial Results and Host Conference Call on November 6, 2014

Dicerna Pharmaceuticals, Inc. (NASDAQ: DRNA), a leader in the development of RNAi-based therapeutics, today announced that the Company will release its third-quarter 2014 financia...

RTI International Metals Schedules 2014 Third Quarter Financial Results Conference Call and Webcast

RTI International Metals, Inc. (NYSE: RTI) today announced that it will host a conference call and live webcast on Wednesday, November 5, 2014, at 10:00 a.m. Eastern Time, to revi...

First DePuy Pinnacle Hip Trial Ends in Defense Verdict, Bernstein Liebhard LLP Reports

The Firm is representing numerous plaintiffs in DePuy Pinnacle lawsuits, all of whom were allegedly injured by a metal-on-metal version of the Pinnacle Hip Replacement System. New York, New York (PRWE...

Stratasys Included in New TV Series "Titan American Built"

Show airs on MAVTV Oct. 24 at 10 p.m. ET Stratasys Ltd. (Nasdaq:SSYS), a global leader of 3D printing and additive manufacturing solutions and GoEngineer, a Stra...

DIA and SureClinical Webinar To Explain New Electronic Master File (eTMF) Data Standards

DIA in cooperation with SureClinical will host a complimentary webinar "How New Electronic Trial Master File (eTMF) Data Standards Can Enhance Clinical Trial Efficiency and Quality" on Octob...

Attorneys at DRK Attorneys Create $1,000 Scholarship for Student Living with Mental Illness

PITTSBURGH, Oct. 24, 2014 /PRNewswire/ -- Creating a brighter path for one student living with mental illness, the attorneys at DRK Attorneys have created a brand-new $1,000 college scholarship d...

Events [1 Associated Events listed on BioPortfolio]

Free webinar: DNA Methylation Changes during Cell Differentiation

This one hour webinar provides an overall perspective on the connections between DNA methylation and other epigenetic marks and the interplay with transcription factors.

Companies [179 Associated Companies listed on BioPortfolio]

Barco N.V.

Barco is a world leader in professional markets, in which it offers display and visualization solutions. Based upon in-depth market knowledge, the company designs and develops solutions for large-scre...

Tenable Network Security Inc.

Tenable Network Security provides continuous network monitoring to identify vulnerabilities, reduce risk and ensure compliance. Our family of products includes SecurityCenter Cont...

ImmuneXcite, Inc.

ImmuneXcite is a privately held biotech company located in Lexington, Massachusetts that is developing the next generation of immune-activating therapies for oncology utilizing a ...

II-VI Optical Systems

II-VI Optical Systems is a leading producer of high precision optical assemblies, objectives, infrared optics and components, windows, domes, thin film coatings, and optical mater...

Tokai Pharmaceuticals, Inc.

Tokai Pharmaceuticals is a U.S. biopharmaceutical company focused on developing new treatments for prostate cancer. The company’s lead drug candidate, galeterone (TOK-001), i...

CherylLeeMD® Sensitive Skin Care

CherylLeeMD® Sensitive Skin Care products are the first skin care products to work with the skin to obtain its optimal equilibrium by simultaneously addressing skin lipid defic...

Navitor Pharmaceuticals, Inc.

Navitor Pharmaceuticals, Inc., is a biopharmaceutical company developing novel medicines by targeting cellular nutrient signaling pathways. The company’s proprietary drug dis...

Pelican Products, Inc.

Pelican Products, Inc. is the global leader in design and manufacture of both high-performance protective case solutions and advanced portable LED lighting systems. Their produ...

Ansun BioPharma

Ansun BioPharma is a clinical stage biopharmaceutical company focused on the development of unique host-directed anti-viral therapies for respiratory viruses. Ansun BioPharma has ...

HealthFleet, Inc.

HealthFleet is the first platform-as-a-service (PaaS) provider for healthcare. HealthFleet’s technology allows providers to deliver their health programs and services online,...

Clinical Trials [1018 Associated Clinical Trials listed on BioPortfolio]

Plerixafor for Stem Cell Mobilization in Normal Donors

The goal of this clinical research study is to learn if treating stem cell donors with filgrastim (G-CSF) and plerixafor (Mozobil®) can cause them to produce a higher number of blood stem...

The Effects of Repetitive Transcranial Magnetic Stimulation in Obese People With BED

The presence of binge eating (BE) is a core feature of bulimic syndromes. Binge eating disorder (BED) is a new category in DSM-5 highly associated with higher body mass index (BMI). The ne...

Developing Novel Microbiota-Targeted Therapies for Irritable Bowel Syndrome

This longitudinal study is being done to understand mechanisms underlying development of irritable bowel syndrome (IBS) and the role of the gut bacteria in development of symptoms. This in...

DLBS2411 Treatment for Ulcer Healing in Non-Bleeding Peptic Ulcers

This is a 2-arm, prospective, double-blind, double-dummy, randomized-controlled study using DLBS2411 at a dose of 250 mg twice daily (before morning and evening meals), or omeprazole at a ...

Busulfan, Melphalan, Fludarabine and T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Followed by Post Transplantation Donor Lymphocyte Infusions

The patients are being offered a stem cell transplant. Stem cells are very early blood cells. They have not yet matured to become red or white blood cells or platelets. They have already r...

Insulin Resistance in Non-alcoholic Fatty Liver Disease

The study is designed to investigate the relationship between insulin resistance and non-alcoholic fatty liver disease (NAFLD) and to investigate potential mechanisms underlying insulin re...

Variability in Perimetry Study

Improved Assessment of Visual Field Change is a trial aimed at investigating mechanisms of visual field testing variability. We have found using larger stimulus size substantially lowers s...

Non-myeloablative Allogeneic Hematopoietic Stem Cell Transplantation (NST) for Patients With Refractory Crohn's Disease

Allogeneic transplantation has been a high-risk procedure, although non-myeloablative conditioning regimens (mini-transplantation) minimizes regimen related toxicity. The investigators, th...

MLN9708 for the Prophylaxis of Chronic Graft-versus-host Disease in Patient Undergoing Allogeneic Transplantation

This is a phase I/II study of MLN9708 for the prophylaxis of chronic graft-versus-host-disease (GVHD) in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT). Duri...

Trial to Evaluate Palifermin in the Reduction of Acute Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Allogeneic Marrow/Peripheral Blood Progenitor Cell (PBPC) Transplantation

The main purpose of this study is to evaluate the effect of palifermin versus placebo in the reduction of severe acute graft versus host disease (GVHD) and severe oral mucositis.

Medical and Biotech [MESH] Definitions

The mechanisms by which a cell becomes internalized in another. The host cell may engulf another as do PHAGOCYTIC CELLS, or the host cell may be invaded by another cell (ENTOSIS), or internalization processes may involve the cooperation of both the host cell and the cell being internalized. Viable cells may remain in non-phagocytic cells (EMPERIPOLESIS), undergo cell division, pass through and then out of the host cell (TRANSCELLULAR CELL MIGRATION), or trigger APOPTOSIS of the invaded cell.

Unconscious process used by an individual or a group of individuals in order to cope with impulses, feelings or ideas which are not acceptable at their conscious level; various types include reaction formation, projection and self reversal.

Processes that translocate macromolecules across the cell envelope of gram negative bacteria, often directly into the host. These effectors modulate the defense response and thereby facilitate survival of the pathogen.

A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.

Defense mechanisms involving approach and avoidance responses to threatening stimuli. The sensitizing process involves intellectualization in approaching or controlling the stimulus whereas repression involves unconscious denial in avoiding the stimulus.

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