Host Defense Mechanisms - Biotech, Pharma and Life Science Channel

10:56 EST 28th February 2015 | BioPortfolio

PubMed Articles [9883 Associated PubMed Articles listed on BioPortfolio]

Microfabricated microporous membranes reduce the host immune response and prolong the functional lifetime of a closed-loop insulin delivery implant in a type 1 diabetic rat model.

Implantation of a medical implant within the body inevitably triggers a host inflammatory response that negatively impacts its function and longevity. Nevertheless, the degree and severity of this res...

Enhanced survival and engraftment of transplanted stem cells using growth factor sequestering hydrogels.

We have generated a bioinspired tunable system of hyaluronic acid (HyA)-based hydrogels for Matrix-Assisted Cell Transplantation (MACT). With this material, we have independently evaluated matrix para...

A novel hybrid microrobot using rotational magnetic field for medical applications.

Magnetically actuated microrobots for such tools have potential accomplish procedures in biological and medical applications. In this paper, a novel magnetically actuated hybrid microrobot with hybrid...

On the predictive ability of mechanistic models for the Haitian cholera epidemic.

Predictive models of epidemic cholera need to resolve at suitable aggregation levels spatial data pertaining to local communities, epidemiological records, hydrologic drivers, waterways, patterns of h...

The early evolving sex hormone environment is associated with significant outcome and inflammatory response differences after injury.

Clinical research characterizing the mechanisms responsible for sex-based outcome differences after injury remains conflicting. Currently lacking is an understanding of the early sex hormone milieu of...

Neuronal communication and synaptic metabolism in childhood epilepsy.

INTRODUCTION. Basic neuroscience and neurometabolism are providing a rapidly increasing amount of knowledge on paediatric epilepsy and, more specifically, on the mechanisms involved in synaptic commun...

Reprogramming patient-derived cells to study the epilepsies.

The epilepsies and related disorders of brain circuitry present significant challenges associated with the use of human cells to study disease mechanisms and develop new therapies. Some of these obsta...

Molecular mechanisms of epilepsy.

Decades of experimental work have established an imbalance of excitation and inhibition as the leading mechanism of the transition from normal brain function to seizure. In epilepsy, these transitions...

Risk of Falls in Patients With Ankylosing Spondylitis.

Risk of vertebral fractures is increased in patients with ankylosing spondylitis (AS). The underlying mechanisms for the elevated fracture risk might be associated with bone and fall-related risks. Th...

Chronic Graft-Versus-Host Disease Presenting as Eosinophilic Fasciitis: Therapeutic Challenges and an Additional Case.

Chronic graft-versus-host disease (cGVHD) is one of the main late complications of allogeneic hematopoietic stem cell transplant and a major contributor to the mortality and morbidity in surviving rec...

News Articles [2506 Associated News Articles listed on BioPortfolio]

The ins and outs of MHC class II-mediated antigen processing and presentation

To play their part in the generation of effective adaptive immune responses, different types of antigen-presenting cell (APC) take up and process antigen in different ways. The length of time that pep...

Bitcoin Run Is The World Scout League Commission’s Newest Project for Charity

Miami, FL (PRWEB) February 28, 2015 The World Scout League Commission (WSLC), an organization that provides training and learning materials to potential EMTs and firefighters, recently announced it...

Senator Tester Introduces the Veterans Education Empowerment Act

Wounded Warrior Project Supports Bill, Which Would Improve On-Campus Support for Student Veterans Senator Jon Tester (D-MT) today introduced the Veterans Education Empo...

Personality and place: New insights on person-environment links

Psychological traits, such as personality and well-being, are spatially and regionally clustered within cities, states, countries, and the world. Four presentations showcase cutting-edge research that...

Paralyzed Veterans of America Responds to Proposed Veterans Healthcare Reform

Paralyzed Veterans of America (Paralyzed Veterans) is voicing its concerns over the report titled “Fixing Veterans Health Care”, released yesterday from Concerned Vet...

Monitor the metabolism in the bacteria by Fourier-transform infrared spectroscopy

Bacteria are masters in adapting to their environment. This adaptability contributes to the bacteria's survival inside their host. Researchers at the Vetmeduni Vienna now demonstrated that the bacteri...

Trimel to Report Financial Results for 2014 and Host Conference Call to Update Investors

Trimel Pharmaceuticals Corporation (TSX:TRL) will report its financial results for the three and twelve month periods ended December 31, 2014 on Thursday, March 5, 2015. ...

AVEO Oncology to Host Conference Call to Discuss Presentation of Final Results and Biomarker Analysis from Phase 2 Study of Tivozanib in Patients with Advanced Colorectal Cancer

AVEO Oncology (NASDAQ:AVEO) today announced that management will host a conference call and webcast on Friday, March 6, 2015, at 8:00 a.m. Eastern Time to discuss the presentation...

Transient details of HIV genome packaging captured

Once HIV-1 has hijacked a host cell to make copies of its own RNA genome and viral proteins, it must assemble these components into new virus particles. The orchestration of this intricate assembly pr...

Trapping the Ebola virus in transit

The deadly Ebola virus makes use of host mechanisms – including a specific type of membrane-bound calcium channel – to gain entry into the cell cytoplasm. LMU researchers now show that blocking th...

Events [0 Results]

None

Companies [188 Associated Companies listed on BioPortfolio]

Tokai Pharmaceuticals

Tokai Pharmaceuticals is a U.S. biopharmaceutical company focused on developing new treatments for prostate cancer. The company’s lead drug candidate, TOK-001, is the first i...

Pannone Lopes Devereaux & West LLC

The attorneys and staff at Pannone Lopes Devereaux & West LLC (PLDW) are committed to developing practical and cost-effective solutions while also being supportive of the communit...

Acceleron Pharma and Celgene Corporation

Acceleron is a clinical stage biopharmaceutical company focused on the discovery, development and commercialization of novel protein therapeutics for cancer and rare diseases. The...

Exostar and Code-N

Exostar powers secure business-to-business information sharing, collaboration and business process integration throughout the value chain. Exostar supports the complex trading nee...

The Object Management Group

What: The Object Management Group® (OMG®) will host an all-day seminar entitled “Cross Domain Threat and Risk Information Exchange Day” on March 23 at the H...

Cambrian Innovation

Cambrian Innovation is a leader in developing biotechnology solutions that extract energy from water. Spun out of MIT in 2006, Cambrian has scaled and validated its proprie...

Newron Pharmaceuticals SpA

Newron Pharmaceuticals SpA is a clinical stage biopharmaceutical company focused on the discovery and development of small molecule drugs for the treatment of central nervous system (CNS) diseases. Ou...

Surface Oncology

Surface Oncology was created to advance next-generation approaches to cancer immunotherapy based on proprietary insights about novel immunotherapy targets and emerging areas of ca...

DigitalGlobe

DigitalGlobe (NYSE: DGI) is a leading provider of commercial high-resolution earth observation and advanced geospatial solutions that help decision makers better understand our ch...

Eyelit Inc.

Eyelit Inc. is the leader in Manufacturing Execution and Quality Management (MES and QMS) solutions for visibility, control, and coordination of manufacturing operations for the a...

Clinical Trials [1058 Associated Clinical Trials listed on BioPortfolio]

Molecular Mechanisms Underlying Prostate Cancer Disparities

The purpose of this study is to further elucidate the molecular mechanisms underlying prostate cancer disparities. In previous work the investigators have identified a set of differential...

Efficacy of a Probiotic Lozenges in Chronic Periodontitis Patients.

Periodontal disease is an infectious disease resulting in inflammation within supporting tissues of the teeth, progressive attachment loss, and bone loss. Epidemiological studies reveal th...

Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)

The central goal of this data repository is to collect data from a large population of patients with diabetic nephropathy and inflammatory renal conditions. This initiative will provide a...

Bioavailability of Phenolic Compounds in Bread

The consumption of wholemeal cereals has been associated with the reduction of several chronic diseases. The mechanisms behind these protective effects may be linked, besides dietary fiber...

Evaluation of Biomarkers Associated With Response to Subsequent Therapies in Subjects With HER2-Positive Metastatic Breast Cancer

This is a multicenter, open-label, Phase II study in subjects with Human epidermal growth factor receptor (HER2)-positive metastatic breast cancer who received at least 2 prior lines of an...

Pharmacokinetics of Rosuvastatin and Atorvastatin in Pediatric Dyslipidemia Patients

This will be a single center, open label, randomized, cross-over study in patients with dyslipidemia comparing the pharmacokinetics of rosuvastatin and atorvastatin in patients with greate...

Selective Depletion of CD45RA+T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD

RATIONALE: Allogeneic hematopoietic stem cell transplant (HSCT) is a treatment that can cure acute leukemia and myelodysplasia. After giving the patient chemotherapy and total body irradia...

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD in Children

This phase II trial studies how well T cell depleted donor peripheral blood stem cell transplant works in preventing graft-versus-host disease in younger patients with high risk hematologi...

(1)H-Nuclear Magnetic Resonance Spectroscopic Imaging of the Brain in Patients Who Receive Neurotoxic Therapy

Central nervous system toxicity is a recognized side effect of certain therapies for cancers, particularly cranial irradiation, intrathecal therapy or systemic high-dose chemotherapy. The...

Evolution of Molecular Biomarkers in Acute Heart Failure Induced by Shock

The relationship between shock, ischemia and reperfusion (I/R) injury, hemodynamic instability, systemic inflammatory response syndrome and multiorgan failure has been extensively investig...

Medical and Biotech [MESH] Definitions

The mechanisms by which a cell becomes internalized in another. The host cell may engulf another as do PHAGOCYTIC CELLS, or the host cell may be invaded by another cell (ENTOSIS), or internalization processes may involve the cooperation of both the host cell and the cell being internalized. Viable cells may remain in non-phagocytic cells (EMPERIPOLESIS), undergo cell division, pass through and then out of the host cell (TRANSCELLULAR CELL MIGRATION), or trigger APOPTOSIS of the invaded cell.

Unconscious process used by an individual or a group of individuals in order to cope with impulses, feelings or ideas which are not acceptable at their conscious level; various types include reaction formation, projection and self reversal.

Processes that translocate macromolecules across the cell envelope of gram negative bacteria, often directly into the host. These effectors modulate the defense response and thereby facilitate survival of the pathogen.

A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.

Defense mechanisms involving approach and avoidance responses to threatening stimuli. The sensitizing process involves intellectualization in approaching or controlling the stimulus whereas repression involves unconscious denial in avoiding the stimulus.

Search BioPortfolio:
Loading
Advertisement
Advertisement
review and buy Host Defense Mechanisms market research data and corporate reports here

Channels Quicklinks