Host Defense Mechanisms - Biotech, Pharma and Life Science Channel

03:41 EDT 26th May 2015 | BioPortfolio

PubMed Articles [10101 Associated PubMed Articles listed on BioPortfolio]

Plant derived and dietary phenolic antioxidants: Anticancer properties.

In this paper, a review of the literature on the phenolic compounds with anticancer activity published between 2008 and 2012 is presented. In this overview only phenolic antioxidant compounds that dis...

Exploration of attenuated total reflectance mid-infrared spectroscopy and multivariate calibration to measure immunoglobulin G in human sera.

Immunoglobulin G (IgG) is crucial for the protection of the host from invasive pathogens. Due to its importance for human health, tools that enable the monitoring of IgG levels are highly desired. Con...

Determination of thiram using gold nanoparticles and Resonance Rayleigh scattering method.

A sensitive, simple and novel method was developed to determine thiram fungicide in water and plant samples. This method was based on the interaction between gold nanoparticles (AuNPs) and thiram fung...

Colorimetric magnetic microspheres as chemosensor for Cu(2+) prepared from adamantane-modified rhodamine and β-cyclodextrin-modified Fe3O4@SiO2 via host-guest interaction.

Adamantane-modified salicylrhodamine B and β-cyclodextrin-modified Fe3O4@SiO2 were assemblied by host-guest interactions which induced novel inclusion complex magnetic nanoparticles (SFIC MNPs) color...

Mathematically modeling the biological properties of gliomas: A review.

Although mathematical modeling is a mainstay for industrial and many scientific studies, such approaches have found little application in neurosurgery. However, the fusion of biological studies and ap...

Traveling bands for the Keller-Segel model with population growth.

This paper is concerned with the existence of the traveling bands to the Keller-Segel model with cell population growth in the form of a chemical uptake kinetics. We find that when the cell growth is ...

Are reactive oxygen species still the basis for diabetic complications?

Despite the wealth of pre-clinical support for a role for reactive oxygen and nitrogen species (ROS/RNS) in the aetiology of diabetic complications, enthusiasm for antioxidant therapeutic approaches h...

Cellular and molecular mechanisms of statins: an update on pleiotropic effects.

Coronary artery disease (CAD) is the leading cause of death worldwide. The efficacy and safety of statins (3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors) in primary and secondary preventi...

An investigation of the carbon nanotube - Lipid interface and its impact upon pulmonary surfactant lipid function.

Multiwalled carbon nanotubes (MWCNTs) are now synthesized on a large scale, increasing the risk of occupational inhalation. However, little is known of the MWCNT-pulmonary surfactant (PS) interface an...

Activation of the Nrf2-regulated antioxidant cell response inhibits HEMA-induced oxidative stress and supports cell viability.

Oxidative stress due to increased formation of reactive oxygen species (ROS) in target cells of dental resin monomers like 2-hydroxyethyl methacrylate (HEMA) is a major mechanism underlying the distur...

News Articles [2513 Associated News Articles listed on BioPortfolio]

Mercy Acceleration to Offer 8-week Running Clinic - Mercy Health System Javon Bea

Janesville, WI (PRWEB) May 23, 2015 Javon Bea Mercy Health System CEO - Mercy Acceleration at the Sports Medicine and Rehabilitation Center, 557 N. Washington St., Janesville, will host an 8-week...

World Health Assembly gives WHO green light to reform emergency and response progamme

Delegates at the World Health Assembly made a series of decisions stemming from the 2014 Ebola virus disease outbreak. These give the WHO Secretariat the go-ahead to carry out structural reforms so it...

Prospects for the development of epigenetic drugs for CNS conditions

Epigenetic mechanisms of gene regulation have an important role in brain development, and evidence is accumulating that some neurological, psychiatric and behavioural disorders can be triggered or mai...

Drug development for airway diseases: looking forward

Advancing drug development for airway diseases beyond the established mechanisms and symptomatic therapies requires redefining the classifications of airway diseases, considering systemic manifestatio...

Perforin and granzymes: function, dysfunction and human pathology

Cytotoxic lymphocytes recognize virus-infected and transformed cells and kill them by apoptosis. Recent studies on the structural and cellular biology of the key mediators of this cytotoxicity — per...

Time to Move Beyond ‘Medieval’ Cyber Security Approach, Expert Says

The nation’s approach to cyber security has much in common with medieval defense tactics, and that needs to change, says a cyber security expert at Missouri University of Science and Technology.

Ebola-free Liberia allowed to host internationals

CAPE TOWN (Reuters) - Liberia can host international soccer matches again after being declared free of the deadly Ebola virus, the Confederation of African Football (CAF) said on Friday.

Liberia allowed to host internationals as Ebola threat recedes

CAPE TOWN (Reuters) - Liberia can host international soccer matches again after being declared free of the deadly Ebola virus, the Confederation of African Football (CAF) said on Friday.

The Phoenix House New England to honor CVS Health's Helena Foulkes

Antoinette AlexanderThe Phoenix House New England, a nonprofit treatment provider, will host on June 2 the 14th annual New England Public Service Award Luncheon at the Omni Providence Hotel, honoring ...

Montreal to host seventh edition of Summer School on Medicines (SSM7)

University of Barcelona to give three €1,500 grants to attend 

Events [0 Results]

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Companies [197 Associated Companies listed on BioPortfolio]

Acceleron Pharma & Celgene Corporation

Acceleron is a clinical stage biopharmaceutical company focused on the discovery, development and commercialization of novel therapeutic candidates that regulate cellular growth a...

NEO Tech

NEO Tech combines the strengths of three leading contract manufacturers: NATEL, EPIC, and OnCore. With over 40 years of heritage in electronics manufacturing, NEO Tech ...

Fonon Corporation

Fonon Corporation is the recognized leader of industrial-grade 3D Additive and Subtractive laser-based material processing systems. Our systems are used world-wide in the semicond...

By Light Professional IT Services, Inc.

By Light Professional IT Services is an ISO 9001:2008 registered and certified Service Disabled Veteran Owned Small Business (SDVOSB) specializing in satellite communications; eng...

Pure Sun Defense

Pure Sun Defense was created by Pure Growth Group in New York. Pure Growth Group (PGG) is a product innovator and marketing consultancy. PGG has launched proprietary brands SK Ene...

Multiple Myeloma Research Foundation and Adaptive Biotechnologies

Adaptive Biotechnologies Corporation is a platform-based, diagnostic-driven company that leverages NGS to profile T-Cell and B-Cell Receptors. This breakthrough enables in-depth c...

Hofstra North Shore-LIJ School of Graduate Nursing and Health Professions

Hofstra University is nationally ranked and recognized private university in Hempstead, NY that is one of only two universities chosen to host consecutive presidential debates (20...

Tokai Pharmaceuticals

Tokai Pharmaceuticals is a U.S. biopharmaceutical company focused on developing new treatments for prostate cancer. The company’s lead drug candidate, TOK-001, is the first i...

Bulova Technologies Group, Inc.

Headquartered in Clearwater, FL, Growth Technologies International, Inc. focuses on disruptive technologies in the fields of defense, alternative energy, alternative healthcare, h...

Nutter McClennen & Fish LLP

Nutter McClennen & Fish LLP represents an international roster of innovative clients involved in a range of sophisticated technologies in the medical device, biotechnology and pha...

Clinical Trials [1120 Associated Clinical Trials listed on BioPortfolio]

fMRI Cholinergic Mechanisms in Schizophrenia

This study aims to determine how clozapine treatment improves neuronal measures of sensory gating in subjects with schizophrenia.

Impact of High-dose Folic Acid Supplementation on Pathways Linked to DNA Formation

Periconceptional supplementation with folic acid - the synthetic form of the B-vitamin folate - reduces the occurrence of adverse pregnancy outcomes such as spina bifida. The underlying bi...

Using EEG Operant Conditioning to Improve Trait Self-Control and Promote Healthy Behavior

The field of neuroeconomics has begun to elucidate neural mechanisms underlying self-control; however, researchers have not yet harnessed neuroeconomics findings to develop interventions f...

Patient-derived Xenograft (PDX) Modeling of Treatment Response for Triple Negative Breast Cancer

This study will determine if patient-derived tumor xenograft (PDX) mouse models can serve as a reliable model for treatment response for individual patients with triple negative breast can...

Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure

Compression garments have been shown to be effective in the treatment of orthostatic hypotension in autonomic failure patients. The purpose of this study is to determine the hemodynamic me...

Vestibular and Multisensory Influence on Bodily and Spatial Representations. Behavioral and Electrophysiological Investigations in Vestibular-defective Patients and Healthy Volunteers

The present project aims at describing how vestibular signals contribute to the multisensory mechanisms of bodily self-consciousness. There is a large body of data regarding the sensory a...

Safety and Efficacy of a Steroid-free, Calcineurin Inhibitor-free, Belatacept-based Immunosuppressive Regimen

Transplant recipients have to take anti-rejection medications to prevent their immune system (the body's natural defense system against illness) from rejecting their new kidney. Most pat...

Clinical Trial on Individual Characteristics Affecting Pain Drug Therapy in Neonates

Children differ from adults with respect to growth and development but also immaturity of various pharmacological mechanisms. Dosing schemes in children are usually derived in an empirica...

Effect of Increasing Motor Cortex Inhibition on Task Specific Dystonia

Dystonia is a disease where muscles in the affected body part are abnormally active. This may result in abnormal postures. The underlying mechanisms are not known. One proposed mechanism ...

TACkLE Study - Tackling Adverse Chemotherapy-associated Late Effects

Testicular cancer (TC) is a rare disease, which mostly affects young men aged 15-35 years. Their life expectancy has greatly improved due to the introduction of platinum-containing chemoth...

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Medical and Biotech [MESH] Definitions

The mechanisms by which a cell becomes internalized in another. The host cell may engulf another as do PHAGOCYTIC CELLS, or the host cell may be invaded by another cell (ENTOSIS), or internalization processes may involve the cooperation of both the host cell and the cell being internalized. Viable cells may remain in non-phagocytic cells (EMPERIPOLESIS), undergo cell division, pass through and then out of the host cell (TRANSCELLULAR CELL MIGRATION), or trigger APOPTOSIS of the invaded cell.

Unconscious process used by an individual or a group of individuals in order to cope with impulses, feelings or ideas which are not acceptable at their conscious level; various types include reaction formation, projection and self reversal.

Processes that translocate macromolecules across the cell envelope of gram negative bacteria, often directly into the host. These effectors modulate the defense response and thereby facilitate survival of the pathogen.

A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.

Defense mechanisms involving approach and avoidance responses to threatening stimuli. The sensitizing process involves intellectualization in approaching or controlling the stimulus whereas repression involves unconscious denial in avoiding the stimulus.

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