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Host Defense Mechanisms - Biotech, Pharma and Life Science Channel

06:58 EST 20th January 2017 | BioPortfolio

PubMed Articles [11303 Associated PubMed Articles listed on BioPortfolio]

Structure-activity relationships of fraxamoside as an unusual xanthine oxidase inhibitor.

Fraxamoside, a macrocyclic secoiridoid glucoside featuring a hydroxytyrosol group, was recently identified as a xanthine oxidase inhibitor (XOI) comparable in potency in vitro to the standard antigout...

Acquisition and adaptation of the airway microbiota in the early life of cystic fibrosis patients.

Cystic fibrosis (CF) is a genetic disease in which bacterial infections of the airways play a major role in the long-term clinical outcome. In recent years, a number of next-generation sequencing (NGS...

Zika Virus RNA Replication and Persistence in Brain and Placental Tissue.

Zika virus is causally linked with congenital microcephaly and may be associated with pregnancy loss. However, the mechanisms of Zika virus intrauterine transmission and replication and its tropism an...

Intra and inter species genetic variability of transferrin receptor gene regions in Trypanosoma evansi isolates of different livestock and geographical regions of India.

Trypanosoma evansi, the aetiological agent of Surra affects a wide range of livestock and wild animals in India. In the present study, we studied intra- and inter species genetic variability in the tr...

The genetic structure of hypoderatid mites (Actinotrichida: Astigmata) parasitizing great cormorant (Phalacrocorax carbo) during host post-breeding dispersal in Milicz, SW Poland.

The astigmatid family Hypoderatidae includes over 80 mite species exhibiting peculiar life cycle. Deutonymphs are parasitic instars inhabiting subcutaneous or visceral tissues of birds and rodents, wh...

Anti-Anisakis sp. antibodies in serum of healthy subjects. Relationship with αβ and γδ T cells.

Anisakiosis is nowadays one of the nematodoses more prevalent in Spain, with rates that oscillate between 0.43% in Galicia (N.W. Spain), and 15.7% and 22.1% in inland and southern regions, respectivel...

New records of host-parasite relationships between Coenagrion scitulum (Rambur, 1842) (Odonata) and water mite larvae (Hydrachnidia) in core and edge host populations.

The relationships between water mite larvae parasitizing Coenagrion scitulum in core and edge populations were described. A total of 636 larvae of 7 water mite species were found on 143 C. scitulum ad...

Prochristianella clarkeae Beveridge, 1990 (Eutetrarhynchidae): a species complex or a species with intraspecific variation in the distribution of its tegumental microtriches?

The microthrix pattern of common forms of the trypanorhynch cestode Prochristianella clarkeae Beveridge, 1990 on which the microscopically visible microtriches almost extended to the posterior end of ...

Occurrence of two novel actinospore types (Cnidaria: Myxosporea) in Brazilian fish farms, and the creation of a novel actinospore collective group, Seisactinomyxon.

The involvement of oligochaetes in the life cycles of fresh water myxozoan parasites in Brazil was investigated. Of 333 oligochaetes collected in a fish farm in the State of São Paulo, three (0.9%) r...

The first successful report of the in vitro life cycle of Chinese Leishmania: the in vitro conversion of Leishmania amastigotes has been raised to 94% by testing 216 culture medium compound.

Chinese Leishmania isolate MHOM/CN/90/SC10H2 (L. H2), which was obtained from the spinal cords of patients from the Sichuan province of China, is an uncharacterized, pathogenic species closely related...

News Articles [2482 Associated News Articles listed on BioPortfolio]

Global Submarinelaunched Missile Market 20172021 Prices from USD $3500

ABSTRACTAbout Submarine Launched MissileSubmarinelaunched missiles are classified into two categories: ballistic missiles SLBMs and cruise missiles SLCMs. While SLBMs are launched vertically, SLCMs ar...

Ossur hf.: FY/Q4 2016 Results - Conference call Wednesday 8 February

Announcement from Össur hf. no: 4/2017 Conference call on Wednesday 8 February at 9:00 CET/ 8:00 GMT/ 3:00 EDT After market closing on Tuesday 7 February, Össur will publish its financial r...

NYU Langone scientists discover mechanism behind many disease-related genetic deletions

Scientists at NYU Langone Medical Center have discovered the mechanisms behind a genetic change known to cause a set of related diseases.

Host-Pathogen interactions: Nucleotide circles of life and death

A phosphodiesterase, CdnP, from Mycobacterium tuberculosis (M. tb.) helps the pathogen evade immune detection by degrading the second messenger cyclic di-AMP that alerts the host to its presence. Gene...

Empowered Partnerships to Host MHAB2017 in Conjunction with Regis University & Regis Neighborhood Health

Denver, CO, January 20, 2017 --(PR.com)-- Empowered Partnerships, a Mental & Behavioral Health Recruiting Outsourcing & Consulting Firm, is hosting their 2nd annual Mental Health Art Benefit ...

Aetiology and management of hereditary aortopathy

In this Review, the authors discuss the pathological mechanisms involved in thoracic aortic aneurysms (TAAs), including extracellular matrix homeostasis, transforming growth factor-β signalling, and ...

PAREXEL International Announces Date of Second Quarter Fiscal Year 2017 Earnings Release and Conference Call

Thursday, January 19th 2017 at 8:00pm UTC BOSTON–(BUSINESS WIRE)– PAREXEL International Corporation (NASDAQ: PRXL) will release financial results for the Second Quarter Fiscal Year 2017 on...

MultiFactor Authentication MFA Market by Model Two, Three, Four, and Five Factor, Application Travel Immigration, Government, Banking, Defense, Commercial Security, Consumer Electronics, Healthcare, and Geography Global Forecast to 2020 Prices from USD

Multifactor authentication is a vast market with a huge scope for growth. The MFA technology plays an important role because it helps to meet legislative compliances, security needs, inter border secu...

PAREXEL International Announces Date of Second Quarter Fiscal Year 2017 Earnings Release and Conference Call

PAREXEL International Corporation (NASDAQ: PRXL) will release financial results for the Second Quarter Fiscal Year 2017 on Wednesday, February 1, 2017 after the close of the stock...

Wayne State University researchers develop behavioral tool to identify tinnitus in rats

A team of researchers from Wayne State University has developed a behavioral tool that may significantly aid in understanding the underlying mechanisms of tinnitus, ultimately leading to new drugs and...

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Companies [224 Associated Companies listed on BioPortfolio]

Lumany, LLC

Established in 2011 in Costa Mesa, CA, Lumany designs and manufactures next-generation laser and illumination products for industrial, biomedical and defense & security applicatio...

Bulova Technologies Group, Inc.

Headquartered in Clearwater, FL, Growth Technologies International, Inc. focuses on disruptive technologies in the fields of defense, alternative energy, alternative healthcare, h...

Vedanta Biosciences

Vedanta Biosciences, a privately held company, was co-founded by PureTech Ventures and a group of world renowned experts in immunology and microbiology. Vedanta Biosciences' mission is to develop a no...

XenoPort

We are a biopharmaceutical company focused on developing a portfolio of internally discovered product candidates for the potential treatment of central nervous system (CNS) disorders. We also have a p...

Unity Biotechnology

Unity Biotechnology is designing therapeutics that prevent, halt or reverse numerous diseases of aging. The Company is targeting biological mechanisms that unify many afflictions,...

CMMI Institute

CMMI Institute (CMMIinstitute.com) is the organization behind Capability Maturity Model Integration (CMMI®), the globally adopted capability improvement framework that g...

Telephus Medical LLC

Telephus Medical, located in San Diego, California, is developing a suite of monoclonal antibody products designed to neutralize key staphylococcal enzymes used to attach to host ...

Armor

The leader in active cyber defense, Armor offers customer-centric security outcomes for retail and eCommerce enterprises, healthcare organizations, payment leaders and financial i...

Histide AG

Histide™ is a biotech intellectual property platform company pioneering a new class of nonmutagenic extracellular therapeutic agents called Cell Recoding Molecules™ (CRM...

Lieber Institute for Brain Development

The mission of the Lieber Institute for Brain Development and the Maltz Research Laboratories is to translate the understanding of basic genetic and molecular mechanisms of schizo...

Clinical Trials [1701 Associated Clinical Trials listed on BioPortfolio]

Surveillance of Azole Resistance in Aspergillus Isolates in Taiwan

Primary objectives: 1. To investigate the prevalence of azole resistance in Aspergillus clinical isolates collected in participating hospitals in Taiwan 2. To investigate ...

Protective Mechanisms Against a Pandemic Respiratory Virus (SLVP024)

The purpose of the study is to investigate and compare the human immune response in epithelial cells of the nasopharyngeal mucosa and in blood to live, attenuated influenza vaccine (LAIV) ...

Effects and Mechanisms of n-3 PUFAs and Irisin on the Incidence of Abnormal Glucose Metabolism After GDM

The purpose of this study is to clarify the relationship between n-3 PUFA and irisin in regulating the glucose metabolism in GDM patients.

Mechanisms of Change in Psychotherapy

Background: Major depressive disorder (MDD) is a prevalent psychiatric condition associated with significant disability, mortality and economic burden. MDD is ranked fourth in terms of dis...

T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) Year 4, 2012

This study will investigate markers, mechanisms and define general predictors for immunological health by comparing influenza vaccine responses in monozygotic and dizygotic twins.

T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) Year 3, 2011

This study will investigate markers, mechanisms and define general predictors for immunological health by comparing influenza vaccine responses in monozygotic and dizygotic twins.

Return to Work Among Patients With Stress Related Mental Disorders - An Intervention in the Swedish Primary Care

The aim of this project is to develop a model for return to work (RTW) for patients sick listed due to stress related mental disorders, which takes into account each patient's specific sit...

T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) Year 2, 2010

This study will investigate markers, mechanisms and define general predictors for immunological health by comparing influenza vaccine responses in monozygotic and dizygotic twins.

Heidelberg Study on Diabetes and Complications

The prospective observational study entitled "Heidelberg Study on Diabetes and Complications" is designed to Monitor the presence and development of diabetic complications in type 1 and ty...

HBV-host cfDNA as Minimal Residual Tumor Marker for HBV-related HCC

Early stage HCC is treated by curative surgical resection or by local ablation (such as radio-frequency) as the current standard of care. The complete removal of clinical visible HCC is th...

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Medical and Biotech [MESH] Definitions

The mechanisms by which a cell becomes internalized in another. The host cell may engulf another as do PHAGOCYTIC CELLS, or the host cell may be invaded by another cell (ENTOSIS), or internalization processes may involve the cooperation of both the host cell and the cell being internalized. Viable cells may remain in non-phagocytic cells (EMPERIPOLESIS), undergo cell division, pass through and then out of the host cell (TRANSCELLULAR CELL MIGRATION), or trigger APOPTOSIS of the invaded cell.

Unconscious process used by an individual or a group of individuals in order to cope with impulses, feelings or ideas which are not acceptable at their conscious level; various types include reaction formation, projection and self reversal.

Processes that translocate macromolecules across the cell envelope of gram negative bacteria, often directly into the host. These effectors modulate the defense response and thereby facilitate survival of the pathogen.

A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.

Defense mechanisms involving approach and avoidance responses to threatening stimuli. The sensitizing process involves intellectualization in approaching or controlling the stimulus whereas repression involves unconscious denial in avoiding the stimulus.

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