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Host Defense Mechanisms - Biotech, Pharma and Life Science Channel

06:16 EDT 26th July 2016 | BioPortfolio

PubMed Articles [11004 Associated PubMed Articles listed on BioPortfolio]

Is Neurotoxicity of Metallic Nanoparticles the Cascades of Oxidative Stress?

With the rapid development of nanotechnology, metallic (metal or metal oxide) nanoparticles (NPs) are widely used in many fields such as cosmetics, the food and building industries, and bio-medical in...

A multi-subband Monte Carlo study on dominance of scattering mechanisms over carrier transport in sub-10-nm Si nanowire FETs.

Dominance of various scattering mechanisms in determination of the carrier mobility is examined for silicon (Si) nanowires of sub-10-nm cross-sections. With a focus on p-type channels, the steady-stat...

Recent progress on the genetics and molecular breeding of brown planthopper resistance in rice.

Brown planthopper (BPH) is the most devastating pest of rice. Host-plant resistance is the most desirable and economic strategy in the management of BPH. To date, 29 major BPH resistance genes have be...

Toll-like receptor 4-related immunostimulatory polysaccharides: Primary structure, activity relationships, and possible interaction models.

Toll-like receptor (TLR) 4 is an important polysaccharide receptor; however, the relationships between the structures and biological activities of TLR4 and polysaccharides remain unknown. Many recent ...

Mechanically flexible and optically transparent three-dimensional nanofibrous amorphous aerocellulose.

Aerocelluloses are considered as "third generation" aerogels after the silica and synthetic polymer-based ones. However, their brittleness and low optical translucency keep quite narrow their fields o...

Bone disorders: Mechanisms and targets.

A Serine/threonine kinase PknL, is involved in the adaptive response of Mycobacterium tuberculosis.

Mycobacterium tuberculosis adapts itself to various environmental stress conditions to thrive inside the phagosome for establishing a chronic infection. Serine/threonine protein kinases (STPKs) play a...

Bacteria as growth-promoting agents for citrus rootstocks.

The microbial community plays an essential role in maintaining the ecological balance of soils. Interactions between microorganisms and plants have a major influence on the nutrition and health of the...

Illumina-based analysis of core actinobacteriome in roots, stems, and grains of rice.

Seed-borne microbiota can transmit vertically from generation to generation and be a favour mutualism between the endosymbionts and hosts. The aim of this study was to investigate the rice-associated ...

A multi-resolution approach to localize neural sources of P300 event-related brain potential.

P300 is probably the most well-known component of event-related brain potentials (ERPs). Using an oddball paradigm, a P300 component can be identified, that is, elicited by the target stimuli recognit...

News Articles [2667 Associated News Articles listed on BioPortfolio]

Campden BRI Brings its Sensory Delights to Lab Innovations

Lab innovations is thrilled to announce that Campden BRI, the UK’s largest independent food and drink research body, will once again be deepening its links with the show. Campden BRI will run a...

Bio-Tech Firm PathSensors Launches High Speed Diagnostic Assays for Plant Safety at APS 2016

New High Sensitivity Bio Sensors Detect Key Threats Such as Phytophthora, Citrus Leprosis Baltimore, Maryland (PRWEB) July 26, 2016 Biotech and pathogen detection solution provider, PathSensors, Inc....

"Behind The Scenes" with James Earl Jones spotlights driving safety programs for Public Television

A new piece will look into improving motor vehicle knowledge for drivers... (PRWEB) July 26, 2016 Safe driving is in the spotlight of an upcoming Behind the Scenes segment with host James Earl Jones....

Targeting CBLB as a potential therapeutic approach for disseminated candidiasis

Jian Zhang and colleagues identify the E3 ubiquitin ligase CBLB as a major inhibitor of host defense against Candida albicans infection and show that targeting CBLB can protect mice from lethal candid...

Idiopathic hypercalciuria and formation of calcium renal stones

The most common predisposing factor for the formation of idiopathic calcium stones is hypercalciuria. Here, the authors discuss the mechanisms of idiopathic calcium stone formation and hypercalciuria ...

Anti-complement-factor H-associated glomerulopathies

Autoantibodies against complement factor H (FH), the main plasma regulatory protein of the alternative pathway of the complement system, are associated with atypical haemolytic uraemic syndrome and C3...

MIDA boronates are hydrolysed fast and slow by two different mechanisms

The staged hydrolysis of N-methylimidodiacetic (MIDA) boronates is a prerequisite for their application in small-molecule constructions. Mechanistic studies now show that two distinct hydrolysis mecha...

New study uncovers way to characterize black box of malignant melanoma

When malignant melanoma metastasizes to the brain, it is a death sentence for most patients. Metastatic melanoma is the deadliest of the skin cancers and the mechanisms that govern early metastatic gr...

AbCellera and Massbiologics partner to discover human antibodies against drug-resistant bacteria

VANCOUVER, BC – AbCellera Biologics Inc., a biotechnology company specializing in the rapid discovery of monoclonal antibodies from natural immune cells, has launched its third antibody discovery co...

BRIEF-Xenon Pharmaceuticals to discuss Q2 2016 financial results

* Xenon pharmaceuticals to host conference call and webcast to discuss second quarter 2016 financial results and provide corporate update Source text for Eikon: Further company coverage:

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Companies [223 Associated Companies listed on BioPortfolio]

Vedanta Biosciences

Vedanta Biosciences, a privately held company, was co-founded by PureTech Ventures and a group of world renowned experts in immunology and microbiology. Vedanta Biosciences' mission is to develop a no...

XenoPort

We are a biopharmaceutical company focused on developing a portfolio of internally discovered product candidates for the potential treatment of central nervous system (CNS) disorders. We also have a p...

Unity Biotechnology

Unity Biotechnology is designing therapeutics that prevent, halt or reverse numerous diseases of aging. The Company is targeting biological mechanisms that unify many afflictions,...

CMMI Institute

CMMI Institute (CMMIinstitute.com) is the organization behind Capability Maturity Model Integration (CMMI®), the globally adopted capability improvement framework that g...

Telephus Medical LLC

Telephus Medical, located in San Diego, California, is developing a suite of monoclonal antibody products designed to neutralize key staphylococcal enzymes used to attach to host ...

Armor

The leader in active cyber defense, Armor offers customer-centric security outcomes for retail and eCommerce enterprises, healthcare organizations, payment leaders and financial i...

Histide AG

Histide™ is a biotech intellectual property platform company pioneering a new class of nonmutagenic extracellular therapeutic agents called Cell Recoding Molecules™ (CRM...

Lieber Institute for Brain Development

The mission of the Lieber Institute for Brain Development and the Maltz Research Laboratories is to translate the understanding of basic genetic and molecular mechanisms of schizo...

Cambrian Innovation

Cambrian Innovation is a leader in developing biotechnology solutions that extract energy from water. Spun out of MIT in 2006, Cambrian has scaled and validated its proprie...

NantKwest, Inc.

NantKwest (Nasdaq:NK) is a pioneering, next generation, clinical-stage immunotherapy company focused on harnessing the unique power of our immune system using natural killer (NK) ...

Clinical Trials [1517 Associated Clinical Trials listed on BioPortfolio]

Bariatric Surgery and Exercise Bone Trial

Despite being effective in weight reduction in severely obese patients, bariatric surgery (BS) negatively influences bone metabolism and increases the risk of falls thereby potentially inc...

Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis

Toxoplasmosis affects one to two newborn each 10000 births. Among them, 1 to 2 % develop learning disabilities or die, and 4 to 27 % develop a chorioretinitis sometimes leading to an ambly...

Ectoin Dermatitis Cream 7% as First-line Therapy of Acute Skin Graft Versus Host Disease

This is a non-interventional prospective study to investigate the treatment response to topical application with Ectoin Dermatitis Cream 7% as first-line therapy of grade I acute skin graf...

Neuroeconomic Approach of Food Nutritionnal Assesment

This fMRI study evaluated the cognitive mechanisms and the cerebral substrate of decision making when evaluating the healthiness of food products with nutritional information displayed eit...

Genetic Susceptibility Factors for Candidemia.

This is a prospective case-control physiopathological study, which main objective is to determine the genetic host factors predisposing to candidemia. Secondary objectives are to develop n...

A Study to Evaluate the Safety, Tolerability, and Activity of KD025 in Subjects With Chronic Graft Versus Host Disease

This study is being conducted to evaluate the safety, tolerability, and activity of KD025 in adult subjects with chronic Graft versus Host Disease (cGVHD).

The Impact of Alcohol Consumption on Tuberculosis Treatment Outcomes

After HIV/AIDS, tuberculosis (TB) remains the second leading cause of death due to an infectious disease globally. Retrospective studies from many countries, including the United States an...

Acute Aerobic Exercise and Neuroplasticity in Depression

Depression is associated with a disruption in the mechanisms that regulate neuroplasticity. Effective treatment and rehabilitation of depression, and other neurological and neuropsychiatri...

COmparison of MicroBiota AccordIng to Age in Crohn's Disease (COMeBACk)

The cause of CD could be different according to age at onset of CD symptoms. Indeed we know that some very young patients at CD diagnosis have particular genetic variants as abnormalities ...

Preventive Antibiotic Serum Levels During Caesarean Section

Background Preventive antibiotic treatment before performing invasive procedures is a basic element in preventing infections. The essence of preventive antibiotic treatment is strengtheni...

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Medical and Biotech [MESH] Definitions

The mechanisms by which a cell becomes internalized in another. The host cell may engulf another as do PHAGOCYTIC CELLS, or the host cell may be invaded by another cell (ENTOSIS), or internalization processes may involve the cooperation of both the host cell and the cell being internalized. Viable cells may remain in non-phagocytic cells (EMPERIPOLESIS), undergo cell division, pass through and then out of the host cell (TRANSCELLULAR CELL MIGRATION), or trigger APOPTOSIS of the invaded cell.

Unconscious process used by an individual or a group of individuals in order to cope with impulses, feelings or ideas which are not acceptable at their conscious level; various types include reaction formation, projection and self reversal.

Processes that translocate macromolecules across the cell envelope of gram negative bacteria, often directly into the host. These effectors modulate the defense response and thereby facilitate survival of the pathogen.

A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.

Defense mechanisms involving approach and avoidance responses to threatening stimuli. The sensitizing process involves intellectualization in approaching or controlling the stimulus whereas repression involves unconscious denial in avoiding the stimulus.

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