Host Defense Mechanisms - Biotech, Pharma and Life Science Channel

00:53 EDT 18th April 2015 | BioPortfolio

PubMed Articles [10018 Associated PubMed Articles listed on BioPortfolio]

Plant derived and dietary phenolic antioxidants: Anticancer properties.

In this paper, a review of the literature on the phenolic compounds with anticancer activity published between 2008 and 2012 is presented. In this overview only phenolic antioxidant compounds that dis...

In silico properties characterization of water-soluble γ-cyclodextrin bi-capped C60 complex: Free energy and geometrical insights for stability and solubility.

Cyclodextrin-related host-guest encapsulation is pivotal to modulate the solubility of C60, thereby promoting its potential therapeutic applications. Here we present a computational study on γ-cyclod...

Temporal sequence of hard and soft tissue healing around titanium dental implants.

The objective of the present review was to summarize the evidence available on the temporal sequence of hard and soft tissue healing around titanium dental implants in animal models and in humans. A s...

A population model capturing dynamics of tuberculosis granulomas predicts host infection outcomes.

Granulomas play a centric role in tuberculosis (TB) infection progression. Multiple granulomas usually develop within a single host. These granulomas are not synchronized in size or bacteria load, and...

The effect of time delay in plant--pathogen interactions with host demography.

Botanical epidemic models are very important tools to study invasion, persistence and control of diseases. It is well known that limitations arise from considering constant infection rates. We replace...

Network-level reproduction number and extinction threshold for vector-borne diseases.

The basic reproduction number of deterministic models is an essential quantity to predict whether an epidemic will spread or not. Thresholds for disease extinction contribute crucial knowledge of dise...

Leptospira interrogans reduces fibrin clot formation by modulating human thrombin activity via exosite I.

Pathogenic bacteria of the genus Leptospira are the etiological agents of leptospirosis, a disease that affects humans and animals worldwide. Although there are an increasing number of studies on the ...

A simple model for the influence of habitat resource availability on lateral clonal spread.

Plant clonal spread is ubiquitous and of great interest, owing both to its key role in plant community assembly and its suitability for plant behaviour research. However, mechanisms that govern spread...

Genome-wide association mapping in a wild avian population identifies a link between genetic and phenotypic variation in a life-history trait.

Understanding the genetic basis of traits involved in adaptation is a major challenge in evolutionary biology but remains poorly understood. Here, we use genome-wide association mapping using a custom...

Overlapping Dopaminergic Pathway Genetic Susceptibility to Heroin and Cocaine Addictions in African Americans.

Drugs of abuse activate the mesolimbic dopaminergic pathway. Genetic variations in the dopaminergic system may contribute to drug addiction. Several processes are shared between cocaine and heroin add...

News Articles [2493 Associated News Articles listed on BioPortfolio]

A Cure for Global Warming plus Drought Relief

by TheOxygenFactory.net, a Subsidiary of Krebs & Sisler, LP In Patent # 8,673,619, TheOxygenFactory.net outlines the renewable energy process which transforms CO2 t...

Kaiser Permanente Reveals TV Ads Featuring Stephen Curry as Latest Game Plan in Partnership with NBA

OAKLAND, Calif., April 17, 2015 /PRNewswire/ -- In an effort to connect with individuals and create stronger, healthier communities, Kaiser Permanente is debuting two new television advertisement...

Pernix Therapeutics Inc. to Report First Quarter 2015 Financial Results

Pernix Therapeutics Holdings, Inc. (NASDAQ:PTX), a specialty pharmaceutical company, announced today that it will release its first quarter 2015 financial results on Friday...

New Hydraulic Motors

High power in a compact design, these hydraulic motors lend themselves to a host of potential applications. Lamina's gerotor hydraulic motors are available in 6 sizes, with different torques ranging f...

Modern Family Dental Care Opens a Second Location in North Charlotte

Dr. Taj Haynes of Modern Family Dental Care is extending his practice to serve the Davis Lake and North Lake neighborhoods of Charlotte, NC. The new office will host a grand opening on April 20, 2015....

Type 2 cytokines: mechanisms and therapeutic strategies

The type 2 cytokine response provides important host-protective functions, but dysregulated type 2 immune responses can contribute to the development of disease. In this Review, the author describes t...

Inflammation: Live long and prosper with Siglecs

Siglec receptors may support longevity in mammals by protecting host cells against damaging free radicals.

Aaron Ciechanover, Israel Cancer Research Fund "Research Professor" Announces Breakthrough in Cancer Research

NEW YORK, April 17, 2015 /PRNewswire-USNewswire/ -- Dr. Aaron Ciechanover, a 2004 Nobel Prize Laureate, and a recipient of the prestigious Research Professorship of the Israel Cancer Research Fund (IC...

Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research

BURNABY, Canada, April 17, 2015 /PRNewswire/ -- Increasing adoption in government projects, growing security concerns, and technological advancement to drive biometric systems market in Saudi Arabia ...

UEI College and Relay for Life Sponsor, "Car Show for a Cause"

STOCKTON, Calif., April 17, 2015 /PRNewswire/ -- On Saturday, May 16, 2015 at 12:00PM, UEI College and Relay for Life will host a fundraiser and car show at the UEI College campus. Logo - http:/...

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Companies [192 Associated Companies listed on BioPortfolio]

Multiple Myeloma Research Foundation and Adaptive Biotechnologies

Adaptive Biotechnologies Corporation is a platform-based, diagnostic-driven company that leverages NGS to profile T-Cell and B-Cell Receptors. This breakthrough enables in-depth c...

Hofstra North Shore-LIJ School of Graduate Nursing and Health Professions

Hofstra University is nationally ranked and recognized private university in Hempstead, NY that is one of only two universities chosen to host consecutive presidential debates (20...

Tokai Pharmaceuticals

Tokai Pharmaceuticals is a U.S. biopharmaceutical company focused on developing new treatments for prostate cancer. The company’s lead drug candidate, TOK-001, is the first i...

Bulova Technologies Group, Inc.

Headquartered in Clearwater, FL, Growth Technologies International, Inc. focuses on disruptive technologies in the fields of defense, alternative energy, alternative healthcare, h...

Nutter McClennen & Fish LLP

Nutter McClennen & Fish LLP represents an international roster of innovative clients involved in a range of sophisticated technologies in the medical device, biotechnology and pha...

Pannone Lopes Devereaux & West LLC

The attorneys and staff at Pannone Lopes Devereaux & West LLC (PLDW) are committed to developing practical and cost-effective solutions while also being supportive of the communit...

Acceleron Pharma and Celgene Corporation

Acceleron is a clinical stage biopharmaceutical company focused on the discovery, development and commercialization of novel protein therapeutics for cancer and rare diseases. The...

Exostar and Code-N

Exostar powers secure business-to-business information sharing, collaboration and business process integration throughout the value chain. Exostar supports the complex trading nee...

The Object Management Group

What: The Object Management Group® (OMG®) will host an all-day seminar entitled “Cross Domain Threat and Risk Information Exchange Day” on March 23 at the H...

Cambrian Innovation

Cambrian Innovation is a leader in developing biotechnology solutions that extract energy from water. Spun out of MIT in 2006, Cambrian has scaled and validated its proprie...

Clinical Trials [1098 Associated Clinical Trials listed on BioPortfolio]

Genetic and Molecular Mechanisms in Assessing Response in Patients With Prostate Cancer Receiving Enzalutamide Therapy

This research trial studies genetic and molecular mechanisms in assessing response in patients with prostate cancer receiving enzalutamide therapy. Androgens can cause the growth of prosta...

Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies

Blood and marrow stem cell transplant has improved the outcome for patients with high-risk hematologic malignancies. However, most patients do not have an appropriate HLA (immune type) ma...

Hematopoietic Stem Cell Transplant for Sickle Cell Disease

This is a phase I/II study of patients with sickle cell disease. It aims to find out if people with sickle cell disease can be cured by changing their immune system before they have blood ...

Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP)

This study is testing the hypothesis of whether continuous positive airway pressure (CPAP) therapy improves placental histopathology and secretory function. The main aims of the study are ...

Genetic and Brain Mechanisms of Naltrexone's Treatment Efficacy for Alcoholism

The overarching aim of this trial is to evaluate naltrexone's efficacy in light of genetic variation and brain response to alcohol cues utilizing a neuroimaging paradigm. This trial has fo...

The Relationship Between Motor Cortex Oxygenation and Motor Function Recovery in Stroke Patients

Stroke is the most common cause of motor function impairment. However, the functional impairment is not totally irreversible. Several mechanisms may involved in both the cortical and motor...

Mechanisms of Social Inequalities in Post-hospitalization Rehabilitation in Patients With Acute Coronary Syndrome

Aim: To identify psychological and socioeconomic predictors of cardiac-rehabilitation (CR) attendance and uncover mechanisms of CR non-attendance. Design: Quantitative, observational, pro...

Exercise Training and Cardiovascular Function in Obesity and in Type 2 Diabetes

Obesity and diabetes increase cardiovascular risk by complex and incompletely known mechanisms. The aims of this study are : 1. to compare cardiac and vascular functions at rest and dur...

Calorie-restricted, Ketogenic Diet and Transient Fasting During Reirradiation for Patients With Recurrent Glioblastoma

Increased glucose metabolism is characteristic for solid tumors. Thereby, glucose is important for the generation of ATP, supply of anabolic substrates and defense against reactive oxygen ...

Influence of Patient Expectations With Lateral Epicondylalgia in Applying Mobilization With Movement

Lateral epicondylalgia affects people of both gender between 1 and 3% of the world population, with up to 15% in the working population reaching an average of 12 weeks off work for this re...

Medical and Biotech [MESH] Definitions

The mechanisms by which a cell becomes internalized in another. The host cell may engulf another as do PHAGOCYTIC CELLS, or the host cell may be invaded by another cell (ENTOSIS), or internalization processes may involve the cooperation of both the host cell and the cell being internalized. Viable cells may remain in non-phagocytic cells (EMPERIPOLESIS), undergo cell division, pass through and then out of the host cell (TRANSCELLULAR CELL MIGRATION), or trigger APOPTOSIS of the invaded cell.

Unconscious process used by an individual or a group of individuals in order to cope with impulses, feelings or ideas which are not acceptable at their conscious level; various types include reaction formation, projection and self reversal.

Processes that translocate macromolecules across the cell envelope of gram negative bacteria, often directly into the host. These effectors modulate the defense response and thereby facilitate survival of the pathogen.

A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.

Defense mechanisms involving approach and avoidance responses to threatening stimuli. The sensitizing process involves intellectualization in approaching or controlling the stimulus whereas repression involves unconscious denial in avoiding the stimulus.

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