Host Defense Mechanisms - Biotech, Pharma and Life Science Channel

00:50 EDT 1st July 2015 | BioPortfolio

PubMed Articles [10190 Associated PubMed Articles listed on BioPortfolio]

Enhanced Antifungal Activity by Ab-Modified Amphotericin B-Loaded Nanoparticles Using a pH-Responsive Block Copolymer.

Fungal infections are an important cause of morbidity and mortality in immunocompromised patients. Amphotericin B (AMB), with broad-spectrum antifungal activity, has long been recognized as a powerful...

Synthesis of Mn3O 4-Based Aerogels and Their Lithium-Storage Abilities.

Mn3O4 aerogels and their graphene nanosheet (GN) composite aerogels were synthesized by a simple supercritical-ethanol process. In the process, supercritical ethanol acted as a reductant to reduce gra...

Bio-functional nano-coatings on metallic biomaterials.

Metals and their alloys have been widely used in all aspects of science, engineering and medicine. Metals in biomedical devices are used due to their inertness and structural functions. They are gener...

Susceptibility to corrosion of laser welding composite arch wire in artificial saliva of salivary amylase and pancreatic amylase.

In this study, laser-welded composite arch wire (CAW) with a copper interlayer was exposed to artificial saliva containing salivary amylase or pancreatic amylase, and the resultant corrosion behavior ...

Synthesis and characterization of silane coated magnetic nanoparticles/glycidylmethacrylate-grafted-maleated cyclodextrin composite hydrogel as a drug carrier for the controlled delivery of 5-fluorouracil.

A novel drug delivery system (DDS), 3-methacryloxypropyl trimethoxy silane coated magnetic nanoparticles polymerized with glycidylmethacrylate-grafted-maleated cyclodextrin (MPTMS-MNP-poly-(GMA-g-MACD...

Bone-like apatite coating on functionalized poly(etheretherketone) surface via tailored silanization layers technique.

Poly(etheretherketone) (PEEK) is a rigid semi-crystalline polymer with outstanding mechanical properties, bone-like stiffness and suitable biocompatibility that has attracted much interest as a biomat...

Review of beetle forewing structures and their biomimetic applications in China: (II) On the three-dimensional structure, modeling and imitation.

This paper reviews the research progress made in China regarding the microstructure of the forewing trabeculae, their anti-peeling and anti-collisional mechanical properties, the three-dimensional (3D...

Plant derived and dietary phenolic antioxidants: Anticancer properties.

In this paper, a review of the literature on the phenolic compounds with anticancer activity published between 2008 and 2012 is presented. In this overview only phenolic antioxidant compounds that dis...

Water soluble biocompatible vesicles based on polysaccharides and oligosaccharides inclusion complexes for carotenoid delivery.

Since carotenoids are highly hydrophobic, air- and light-sensitive hydrocarbon compounds, developing methods for increasing their bioavailability and stability towards irradiation and reactive oxygen ...

Molecular and Physiological Mechanisms of Heavy Metal Tolerance in Atriplex halimus.

A study was carried out to identify the mechanisms underlying stress caused by Cd and Pb accumulation in leaves of Atriplex halimus L. collected from habitats representing different kinds of pollution...

News Articles [2663 Associated News Articles listed on BioPortfolio]

Reproductive endocrinology: Paracetamol-induced endocrine disruption in human fetal testes

Paracetamol is the most frequently used medication during pregnancy. Among concerns about its prenatal use, the association with failure of the testes to descend in neonates is the latest. A new study...

Beware of animal diseases as biological weapons, health experts say

PARIS (Reuters) - The World Health Organization, animal health and national defense officers called on Tuesday for wider international cooperation to avoid the spread of animal diseases that could be ...

Report: U.S. Pro Sports Shifting to More Sustainable Game Day Food

Green Sports Alliance and NRDC release first-of-its-kind study on concessionaires and venues providing fans with local, healthy fare Leading professional sports venues that se...

Opportunities and challenges of radiotherapy for treating cancer

Although dramatic changes in the delivery of radiation therapy have occurred, the impact of radiobiology on the clinic has been far less substantial. New advances are uncovering some of the mechanisti...

A Monster Movie Nailed South Korea's MERS Problem

Anyone trying to understand South Korea's struggle with the MERS virus outbreak should take a look at a Korean monster movie called "The Host" from 2006. "The Host" doesn't actually predict South...

The International Essential Tremor Foundation Funds Ground-Breaking Research

Research grants awarded to scientists studying essential tremor, the neurological disorder affecting more than 10 million Americans. Lenexa, Kan. (PRWEB) June 30, 2015 The International Essential Tre...

Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies

Recent advances in genetics have deepened our understanding of the pathogenic mechanisms behind autoimmune and immune-mediated diseases. This has revealed both shared pathways and a considerable degre...

Neural commitment of human pluripotent stem cells under defined conditions recapitulates neural development and generates patient‐specific neural cells

Standardization of culture methods for human pluripotent stem cell (PSC) neural differentiation can greatly contribute to the development of novel clinical advancements through the comprehension of ne...

Noblis and Government Scientists Identify New Genomic Signatures of Ebola Using Whole Genomic Sequencing and Innovative BioVelocity Analytics Tool

Paper published in the scientific journal “Viruses” Falls Church, VA (PRWEB) June 30, 2015 Noblis, Inc., a leading provider of science, technology, and strategy services to the federal government...

Zoetis to Host Webcast and Conference Call on Second Quarter 2015 Financial Results

Zoetis Inc. (NYSE:ZTS) will host a webcast and conference call at 8:30 a.m. (EDT) on Tuesday, Aug. 4, 2015. Chief Executive Officer Juan Ramón Alaix and Executive Vice Pre...

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Companies [203 Associated Companies listed on BioPortfolio]

Exostar and Taigle

Exostar powers secure business-to-business information sharing, collaboration and business process integration throughout the value chain. Exostar supports the complex trading nee...

Blank Rome LLP

With more than 500 attorneys serving clients around the globe, Blank Rome is an international law firm representing businesses and organizations ranging from Fortune 500 companies...

Exovita Biosciences, Inc.

New Mexico-based Exovita Biosciences is working to harness the body’s own defenses against cancer. Exovita is developing the next generation of biological cancer therapeutics...

Acceleron Pharma & Celgene Corporation

Acceleron is a clinical stage biopharmaceutical company focused on the discovery, development and commercialization of novel therapeutic candidates that regulate cellular growth a...

Allele Biotechnology & Pharmaceuticals, Inc.

Allele Biotechnology and Pharmaceuticals, Inc. is a private, San Diego-based company that explores the mechanisms of biological processes to develop technologies and products for ...

NuCana

NuCana® is a rapidly growing, clinical stage biopharmaceutical company with a broad development portfolio of novel anti-cancer medicines. The Company’s proprietary ProTide...

Camgian Microsystems Corporation

Named by Inc. Magazine as one of America’s fastest growing private companies, Camgian Microsystems delivers award winning Internet of Thing (IoT) services for commercial and ...

NEO Tech

NEO Tech combines the strengths of three leading contract manufacturers: NATEL, EPIC, and OnCore. With over 40 years of heritage in electronics manufacturing, NEO Tech ...

Fonon Corporation

Fonon Corporation is the recognized leader of industrial-grade 3D Additive and Subtractive laser-based material processing systems. Our systems are used world-wide in the semicond...

By Light Professional IT Services, Inc.

By Light Professional IT Services is an ISO 9001:2008 registered and certified Service Disabled Veteran Owned Small Business (SDVOSB) specializing in satellite communications; eng...

Clinical Trials [1146 Associated Clinical Trials listed on BioPortfolio]

Irradiated Blood Versus Non Irradiated Blood Transfusions in Craniosynostosis Repair

Blood transfusions are required for patients undergoing a craniosynostosis repair due to the significant amount of blood loss. Irradiated or non-irradiated transfusions have many risks inv...

Rapid Infusion Rituximab, Hematologic, Oncologic, and Rheumatologic Disorders

Rituximab is frequently used in adult and pediatric cancers, blood disorders, lymphoma (a cancerous growth made up of lymphoid tissue), graft-versus-host-disease (complication that can occ...

Respiratory Syncytial Virus Human Challenge in Healthy Adult Volunteers

Background: - Respiratory syncytial virus (RSV) can cause respiratory infections. Some of these can be life-threatening, especially in young children, the elderly, and people with weak im...

Look at Food and Lose Your Fear - Evaluation of a Computerized Attention Training (CAT) for Anorexia Nervosa Patients

The purpose of this study is to test the therapeutic effects of a computerized attention training for patients with Anorexia Nervosa (AN). The primary aim is to determine if a computerized...

Feasibility of Measuring Exercise's Effects on Molecular Mechanisms of Disease Progression in Prostate Cancer

The investigators aim to evaluate the feasibility of a larger clinical trial assessing an exercise program during the "teachable moment" in patients with prostate cancer and measuring its ...

Extended Use of Cannabidiol for the Prevention of Graft-versus-host-disease

Cannabidiol (CBD), a non-psychotropic ingredient of Cannabis sativa possesses potent anti-inflammatory and immunosuppressive properties. In a recent prospective phase II study (NCT01385124...

Coping Skills Training for Living With Chronic Low Back Pain

Up to 80% of Australians experience back pain and 10% have significant disability as a result. There is a critical need for the development and evaluation of innovative treatments that hav...

Stent vs. Indomethacin for Preventing Post-ERCP Pancreatitis

Background: Pancreatitis is the most frequent complication of endoscopic retrograde cholangiopancreatography (ERCP), accounting for substantial morbidity, occasional mortality, and increas...

Study of Na-APR-1 (M74)/Alhydrogel® Co-administered With Na-GST-1/Alhydrogel in Brazilian Adults

Na-GST-1 and Na-APR-1 are proteins expressed during the adult stage of the Necator americanus hookworm life cycle that are thought to play a role in the parasite's degradation of host hemo...

Combination Therapy With Carfilzomib for the Antibody-Mediated Rejection Diagnosis in Lung Transplantation

The clinical trial is a Phase II open label, single-arm pilot study to evaluate the safety and efficacy of combination therapy with carfilzomib, plasma exchange and intravenous immunoglobu...

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Medical and Biotech [MESH] Definitions

The mechanisms by which a cell becomes internalized in another. The host cell may engulf another as do PHAGOCYTIC CELLS, or the host cell may be invaded by another cell (ENTOSIS), or internalization processes may involve the cooperation of both the host cell and the cell being internalized. Viable cells may remain in non-phagocytic cells (EMPERIPOLESIS), undergo cell division, pass through and then out of the host cell (TRANSCELLULAR CELL MIGRATION), or trigger APOPTOSIS of the invaded cell.

Unconscious process used by an individual or a group of individuals in order to cope with impulses, feelings or ideas which are not acceptable at their conscious level; various types include reaction formation, projection and self reversal.

Processes that translocate macromolecules across the cell envelope of gram negative bacteria, often directly into the host. These effectors modulate the defense response and thereby facilitate survival of the pathogen.

A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.

Defense mechanisms involving approach and avoidance responses to threatening stimuli. The sensitizing process involves intellectualization in approaching or controlling the stimulus whereas repression involves unconscious denial in avoiding the stimulus.


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