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Host Defense Mechanisms - Biotech, Pharma and Life Science Channel

09:57 EDT 23rd July 2014 | BioPortfolio

PubMed Articles [9394 Associated PubMed Articles listed on BioPortfolio]

Effect of fermentation on the antioxidant activity in plant-based foods.

This study provides an overview of the factors that influence the effect of fermentation on the antioxidant activity and the mechanisms that augment antioxidative activities in fermented plant-based f...

In vitro total antioxidant capacity and anti-inflammatory activity of three common oat-derived avenanthramides.

To better understand mechanisms underlying the health benefits of oats, the free radical scavenging capacities of oat avenanthramides 2c, 2f, and 2p and their ability to inhibit NF-κB activation were...

Role of the potassium channel KCa3.1 in diabetic nephropathy.

There is an urgent need to identify novel interventions for mitigating the progression of diabetic nephropathy. Diabetic nephropathy is characterized by progressive renal fibrosis, in which tubulointe...

Cyclodextrin-coated denim fabrics as novel carriers for ingredient deliveries to the skin.

Garments with coverage of a large part of the body generate an exceptional opportunity for transferring active ingredient to the skin. A fabric finished with β-cyclodextrin derivatives can play a rol...

Effect and mechanisms of curdlan sulfate on inhibiting HBV infection and acting as an HB vaccine adjuvant.

In this study, the effect and mechanisms of curdlan sulfate (CS3) on hepatitis B virus (HBV) infection and promoting immune response of the mice immunized with recombinant hepatitis B surface protein...

Impact of ghosts on the viscoelastic response of gelatinized corn starch dispersions subjected to small strain deformations.

Corn starch dispersions (5.0% w/w) were gelatinized by heating at 90°C for 20min using gentle stirring. Under these conditions, ghosts, which are insoluble material with high amylopectin content, wer...

Potentiometry up to 275°C: Example of pH titrations of cobalt ferrite particles.

High temperature potentiometry (or pH-metry) is needed for specific hydrothermal applications such as acid-base titration of metallic oxides particles to predict their reactivity toward dissolved spec...

Role of the BaeSR two-component regulatory system in resistance of Escherichia coli O157:H7 to allyl isothiocyanate.

Allyl isothiocyanate (AITC) is an essential oil with antimicrobial activity against Escherichia coli O157:H7. The ability of E. coli O157:H7 to withstand inhibitory AITC concentrations and the role o...

Listeria ivanovii ATCC 19119 strain behaviour is modulated by iron and acid stress.

It has been suggested that the rarity of human listeriosis due to Listeria ivanovii reflects not only host tropism factors but also the rare occurrence of this species in the environment, compared wit...

Emerging Roles of MicroRNA in the Embryo-Endometrium Cross Talk.

Embryo implantation requires a reciprocal interaction between the blastocyst and endometrium and is associated with complex regulatory mechanisms. Since their discovery, microRNAs have become prominen...

News Articles [2916 Associated News Articles listed on BioPortfolio]

Fluidigm to Announce Q2 2014 Financial Results and Host Conference Call for Investors

Fluidigm Corporation (NASDAQ:FLDM) will report its second quarter 2014 financial results on July 31, 2014, after close of market. Gajus Worthington, Fluidigm president an...

TicTocStop.org is Improving the Lives of Kids with Tourette Syndrome by Lessening the Tics Associated with the Disorder; Help Them Do It During "A September to Remember"

CBS Sports Personality Craig Carton's TicTocStop Foundation is helping to improve the lives of kids with Tourettes by decreasing the Tics Associated with the neurological disorder. New York, New Y...

Aerie Pharmaceuticals to Announce Second Quarter 2014 Financial Results and Host Conference Call on Wednesday, August 6, 2014

Aerie Pharmaceuticals, Inc. (NASDAQ:AERI) announced today that its second quarter 2014 financial results will be released after the market closes on Wednesday, August 6, 2014. Fol...

Vision UK Brings a Whole Host of Imaging and Vision Technologies to Photonex

Vision UK brings a whole host of imaging and vision technologies to the PHOTONEX exhibition in Coventry, 15th and 16th October 2014 and is supported by the UK Industrial Vision Association (UKIVA). Th...

Autoimmune diseases share certain pathogenic mechanisms with cancer

Autoimmune disorders may share certain pathogenic mechanisms with cancer, according to a new report by George Washington University researcher Linda Kusner, Ph.D., published in PLOS ONE on July 22.

American Venous Forum Registration Open: Vein Forum, Fellows Course

New York, NY, July 23, 2014 --(PR.com)-- Vein Forum: Comprehensive Venous Management for the Practicing Clinician The American Venous Forum (AVF) will host the Vein Forum: Comprehensive Venous Manag...

Natural GMOs Part 202. Viral relics show cancer's 'footprint' on our evolution

From myScience UKCancer has left its ’footprint’ on our evolution, according to a study which examined how the relics of ancient viruses are preserved in the genomes of 38 mammal species.Viral rel...

Natural GMOs Part 203. Viral relics show cancer's 'footprint' on our evolution

From myScience UKCancer has left its ’footprint’ on our evolution, according to a study which examined how the relics of ancient viruses are preserved in the genomes of 38 mammal species.Viral rel...

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

Age at menarche is a marker of timing of puberty in females. It varies widely between individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, cardiovascular diseas...

Deferasirox nephrotoxicity—the knowns and unknowns

Since the approval of deferasirox for patients with blood-transfusion-related iron overload by the FDA in 2005, >150,000 patient-years of exposure have occurred. However, nephrotoxicity is a common ad...

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Companies [169 Associated Companies listed on BioPortfolio]

Hyperice Inc.

Hyperice is a recovery technology company specializing in portable high performance sports medicine and orthopedic devices that provide preventative treatment, accelerate injury r...

Riverbed Technology

Riverbed at more than $1 billion in annual revenue is the leader in Application Performance Infrastructure, delivering the most complete platform for Location-Independent Computin...

Tokai Pharmaceuticals

Tokai Pharmaceuticals is a U.S. biopharmaceutical company focused on developing new treatments for prostate cancer. The company’s lead drug candidate, TOK-001, is the first i...

PolyMedix Inc.

PolyMedix is a publicly traded emerging biotechnology company focused the development of novel drugs and biomaterials for the treatment of infectious diseases and acute c...

arGentis Pharmaceuticals, LLC

arGentis Pharmaceuticals is a privately-held diversified biopharmaceutical company dedicated to the licensing, development and commercialization of novel classes of therapies to t...

Advaxis, Incorporated

Based in North Brunswick, New Jersey, Advaxis is developing proprietary Listeria monocytogenes (Lm) cancer vaccines based on technology developed by Dr. Yvonne Paterson, professor...

BioForward BioForward

BioForward is the member-driven state association that is the voice of Wisconsin’s biotechnology industry. We provide a means for our members to be heard regarding creation o...

Kyto Biopharma Inc.

Kyto Biopharma Inc. is a Florida based biotechnology company operating from Toronto, Canada, developing monoclonal antibody therapies for the treatment of various forms of cancer....

Trimeris, Inc.

Trimeris, Inc. (Nasdaq: TRMS) is a biopharmaceutical company engaged in the commercialization of therapeutic agents for the treatment of viral disease. The core technology platfor...

Synta Pharmaceuticals Corp.

Synta Pharmaceuticals Corp. is a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to extend and enhance the lives of patients...

Clinical Trials [997 Associated Clinical Trials listed on BioPortfolio]

Tacrolimus, Sirolimus and Ustekinumab vs. Tacrolimus and Sirolimus for the Prevention of Acute Graft-Versus-Host Disease

To determine whether treatment with ustekinumab will alter the ratio of Treg/total CD4+ cells in peripheral blood at day 30 post-hematopoietic cell transplantation (HCT).

Genetic Study of Peginterferon Treatment in Hepatitis B Patients: The GIANT-B Study

Background and rationale Chronic hepatitis B is the most common cause of liver cirrhosis and hepatocellular carcinoma worldwide.(1) Antiviral therapy with oral nucleoside analogs and inter...

Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

This randomized phase II trial is studying how well giving tacrolimus and mycophenolate mofetil (MMF) together with or without sirolimus works in preventing acute graft-versus-host disease...

Combined Haploidentical-Cord Blood Transplantation for Adults and Children

The primary objective is to assess the rate of engraftment with combined haploidentical-cord blood transplantation. The secondary objective is to evaluate the incidence and severity of acu...

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

This study is a research study involving subjects who are diagnosed with a malignant disease, that has either failed standard therapy or is unlikely to be cured with standard non-transplan...

MAP-IDM: Identification of Molecular Markers of Sudden Death at the Acute Phase of Myocardial Infarction

We propose a comparative case-control study on the 2 following groups of patients: - Cases: 500 patients with ventricular fibrillation at the acute phase of myocardial infarct,...

ALL-SCT BFM International- HSCT in Children and Adolescents With ALL

With this protocol the ALL-SCT BFM international study group wants - to evaluate whether hematopoietic stem cell transplantation (HSCT) from matched family or unrelated donors (MD...

Methylphenidate to Improve Balance and Walking in MS

Methylphenidate is an amphetamine-like psychomotor stimulant drug currently approved for the treatment of attention-deficit hyperactivity disorder (ADHD), postural orthostasis tachycardia...

Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders

The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of,...

Assessing the Fit of Motivational Interviewing by Cultures With Adolescents

Hispanic adolescents experience more severe alcohol-related consequences due to their alcohol abuse and yet significantly fewer Hispanic adolescents receive alcohol treatment, particularly...

Medical and Biotech [MESH] Definitions

The mechanisms by which a cell becomes internalized in another. The host cell may engulf another as do PHAGOCYTIC CELLS, or the host cell may be invaded by another cell (ENTOSIS), or internalization processes may involve the cooperation of both the host cell and the cell being internalized. Viable cells may remain in non-phagocytic cells (EMPERIPOLESIS), undergo cell division, pass through and then out of the host cell (TRANSCELLULAR CELL MIGRATION), or trigger APOPTOSIS of the invaded cell.

Unconscious process used by an individual or a group of individuals in order to cope with impulses, feelings or ideas which are not acceptable at their conscious level; various types include reaction formation, projection and self reversal.

Processes that translocate macromolecules across the cell envelope of gram negative bacteria, often directly into the host. These effectors modulate the defense response and thereby facilitate survival of the pathogen.

A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.

Defense mechanisms involving approach and avoidance responses to threatening stimuli. The sensitizing process involves intellectualization in approaching or controlling the stimulus whereas repression involves unconscious denial in avoiding the stimulus.

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