Hyaluronic acid Sanofi - Biotech, Pharma and Life Science Channel

00:46 EST 27th January 2015 | BioPortfolio

PubMed Articles [6931 Associated PubMed Articles listed on BioPortfolio]

Influence of DGAT1 K232A Polymorphism on Milk Fat Percentage and Fatty Acid Profiles in Romanian Holstein Cattle.

Milk and dairy products are considered the main sources of saturated fatty acids, which are a valuable source of nutrients in the human diet. Fat composition can be adjusted through guided nutrition o...

Molecular Cloning, Sequence, and Phylogenetic Analysis of T Helper 1 Cytokines of Pashmina Goats.

Cytokines play an important role in regulation of immune responses either in health or disease. In the present study, the cDNAs encoding mature Interleukin (IL)-2, interferon gamma (IFN-γ), and IL-12...

Using Contaminated Plants Involved in Phytoremediation for Anaerobic Digestion.

This study investigated the anaerobic digestion capability of five plants and the effects of copper (Cu) and S,S'-ethylenediaminedisuccinic acid (EDDS, a chelator widely used in chelant-assisted phyto...

Negative Effects of Chelants on Soil Qualities of Five Soil Series.

Due to the low phytoavailability of some heavy metals (HMs), a prolonged period is required when phytoextraction is used to remove these HMs from contaminated soils. The use of chelants and other chem...

Zinc Accumulation and Tolerance in Solanum nigrum are Plant Growth Dependent.

Zinc tolerance, accumulation, and organic acid production by Solanum nigrum, a known Zn accumulator, was studied during pre- and post-flowering stages of development. The plants, when challenged with ...

Hyperaccumulator Oilcake Manure as an Alternative for Chelate-Induced Phytoremediation of Heavy Metals Contaminated Alluvial Soils.

The ability of hyperaccumulator oilcake manure as compared to chelates was investigated by growing Calendula officinalis L for phytoremediation of cadmium and lead contaminated alluvial soil. The comb...

Spectroscopic determination of metabolic and mineral changes of soya-chunk mediated by Aspergillus sojae.

Time dependent changes of primary (GC-MS), isoflavones (LC-MS) and minerals (ICP-OES) content of fermented soya-chunk were compared with un-fermented (0H) soya-chunk and presented. Results revealed th...

Variability in almond oil chemical traits from traditional cultivars and native genetic resources from Argentina.

Almond (Prunus dulcis (Miller) D.A. Webb) genetic resources (Marcona, Guara, Non Pareil, IXL, AI, Martinelli C, Emilito INTA, Cáceres Clara Chica, Javier INTA) were studied during two consecutive cro...

A simple and sensitive HPLC method based on pre-column fluorescence labelling for multiple classes of plant growth regulator determination in food samples.

The determination of trace plant growth regulator (PGR) has received more and more attentions in the field of phytophysiology and food safety. But the simple and sensitive method for simultaneously an...

Evaluation of the risk/benefit associated to the consumption of raw and cooked farmed meagre based on the bioaccessibility of selenium, eicosapentaenoic acid and docosahexaenoic acid, total mercury, and methylmercury determined by an in vitro digestion model.

The bioaccessibility of total lipids, EPA, DHA, Se, Hg, and MeHg in raw and cooked meagre (Argyrosomus regius) was studied by using an in vitro digestion method. A risk-benefit assessment of raw and c...

News Articles [2090 Associated News Articles listed on BioPortfolio]

Massively parallel single-amino-acid mutagenesis

A comprehensive allelic series for a protein of interest with a single mutation per cDNA template can be generated using a combination of microarray-based DNA synthesis and overlap-extension mutagenes...

Nanoparticles that deliver oligonucleotide drugs into cells described in Nucleic Acid Therapeutics

(Mary Ann Liebert, Inc./Genetic Engineering News) Therapeutic oligonucleotide analogs represent a new and promising family of drugs that act on nucleic acid targets such as RNA or DNA; however, their ...

Arginine‐dipeptides affect insulin aggregation in a pH and ionic‐strength dependent manner

Solutions containing arginine or mixtures of arginine and other amino acids are commonly used for protein liquid formulations to overcome problems such as high viscosities, aggregation, and phase sepa...

FDA approves Teva's generic version of AstraZeneca's Nexium

(Reuters) - The U.S. Food and Drug Administration said it approved Teva Pharmaceutical Industries Ltd's generic version of AstraZeneca Plc's Nexium to treat acid reflux, the agency's first generic app...

Regeneron and Sanofi Announce Praluent BLA Accepted for Priority Review by FDA

Regeneron Pharmaceuticals and Sanofi today announced that the U.S. Food and Drug Administration (FDA) has accepted for priority review the Biologics License Application (BLA) for  (alirocumab). Under...

wikifolio whispers p.m. zu Lufthansa, Qualcomm Incorporated, Bechtle, General Electric, BASF, Aareal Bank, Continental, Sanofi und China Ming Yang

Aktuelle Kommentare aus dem wikifolio-Universum. Mit Links zu den jeweiligen Depots, damit man sieht, wie erfolgreich die Kommentatoren mit ihren Einschätzungen sind und wie sich die genannten Inpu.....

Sanofi and Regeneron’s Praluent BLA gains priority review from US FDA

The US Food and Drug Administration has accepted for priority review the Biologics License Application (BLA) for Praluent (alirocumab), which is under development by French pharma major Sanofi and US...

Regeneron/Sanofi in pole position for PCSK inhibitor launch

Sanofi and Regeneron could have approval for their new cholesterol-lowering drug alirocumab in the US before the end of July, giving it a real chance of beating rival Amgen to market.The Food and Drug...

US priority review for Sanofi/Regeneron cholesterol drug

US priority review for Sanofi/Regeneron cholesterol drug

FDA to expedite review of cholesterol drug from Regeneron, Sanofi

The FDA has granted priority-review status to a marketing application submitted by Regeneron Pharmaceuticals and Sanofi for t -More- 

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Companies [66 Associated Companies listed on BioPortfolio]

QIAGEN

QIAGEN is one of the world’s leading providers of innovative enabling technologies and products for separating and purifying nucleic acids (DNA and RNA). Since 1986, the Company has developed and ma...

TapImmune Inc.

TapImmune Inc. is an immunotherapy company specializing in the development of innovative vaccine technologies for the treatment of cancer and infectious disease. The Company’...

Creative Biogene

Creative Biogene provides kits, reagents, and services that help researchers explore questions about gene discovery, regulation, and function. Creative Biogene holds a leadership position in the glo...

Reinnervate Ltd

Reinnervate is a market leading company in the fast growing 3D cell culture market. The Alvetex® family of 3D cell culture products provide a flexible platform that allows scientists in any life...

Oasis Diagnostics Corporation

Oasis Diagnostics® is an emerging Vancouver, WA based company focused on the design, development and commercialization of salivary diagnostic tools with applications at the poi...

ImmunID

ImmunID is pioneering the field of molecular immune diagnostics since 2005, offering two commercial products. Its proprietary CE-marked flagship product ImmunTraCkeR evaluates the...

Axiall Corporation

Axiall Corporation is a leading integrated chemicals and building products company. It is an international manufacturer of chlor-alkali and derivatives, chlorovinyls and aromatics...

SANOFI

SANOFI concentrate their research efforts where the most pressing medical needs and public health issues are, bringing solutions to patients and contributing to a healthier society worldwide: D...

Source BioScience LifeSciences

Source BioScience LifeSciences are European leaders in DNA sequencing, genomic services, bioinformatic analyses and offers a comprehensive portfolio of genomic reagents and antibodies. Source Bio...

Bionest Partners Inc.

Bionest Partners Inc. provides strategy consulting services exclusively for the life science industries to help pharmaceutical, biopharmaceutical, diagnostics, biotechnology, and ...

Clinical Trials [1291 Associated Clinical Trials listed on BioPortfolio]

Fatty Acid Levels and Memory in Breastfed Children

Purpose: To explore the relation between breastmilk nutrients and the cognitive abilities of breastfed infants. Phase 1: Near 3 months of age child and mother saliva samples for DNA obtai...

Saturated Fat Versus Monounsaturated Fat and Insulin Action

High intakes of saturated fat are associated with diabetes. Our work has shown that the two most common fatty acids in the North American diet, palmitic acid (saturated fat) and oleic aci...

Zoledronic Acid for Osteoporosis in the Elderly

This trial will examine the safety, efficacy and feasibility of a single dose of intravenous zoledronic acid in the maintenance of skeletal integrity for frail, institutionalized women, wh...

Gonorrhea and Chlamydia HIV-infected Men Who Have Sex With Men

Hypothesis: Men who have sex with men (MSM) are at higher risk for sexually transmitted diseases. Currently, free testing for sexually transmitted diseases is only being performed in urine...

Comparison of Autologous Platelet-rich Plasma With Hyaluronic Acid for the Treatment of Osteoarthritis of the Knee Joint

The purpose of this study is to compare the efficacy of platelet-rich plasma versus hyaluronic acid intra-articular injections for the treatment of osteoarthritis of knee joint. The...

Safety and Efficacy of Recombinant Human Acid Alpha-Glucosidase in the Treatment of Classical Infantile Pompe Disease

Pompe disease is caused by a deficiency of a critical enzyme in the body called acid alpha glucosidase (GAA). Normally, GAA is used by the body's cells to break down glycogen (a stored fo...

1 Year Open-label Extension to CZOL446H2337 Safety and Efficacy Trial of Zoledronic Acid Twice Yearly in Osteoporotic Children Treated With Glucocorticoids for Chronic Inflammatory Conditions

This 1-year open-label extension to CZOL446H2337 is designed to evaluate the safety and efficacy of zoledronic acid twice yearly in osteoporotic children treated with glucocorticoids for c...

Skin Effects of a Topical Amino Acid Moisturizing Cream and Desonide in Atopic Dermatitis

The purpose of this study is to compare the effects of an amino acid moisturizing cream and desonide cream in reducing skin symptoms associated with AD/eczema in subjects with mild to mode...

XELOX Versus FOLFOX for Advanced Gastric Cancer (AGC)

The purpose of this study is to identify the non-inferiority of the combination therapy of Capecitabine and Oxaliplatin compared with the combination therapy of Fluorouracil/Folinic acid a...

Sorafenib Tosylate, Valproic Acid, and Sildenafil Citrate in Treating Patients With Recurrent High-Grade Glioma

This phase II trial studies how well sorafenib tosylate, valproic acid, and sildenafil citrate works in treating patients with recurrent high-grade glioma. Sorafenib tosylate, valproic aci...

Medical and Biotech [MESH] Definitions

A group of high molecular weight chondroitin sulfate proteoglycans that form aggregates with HYALURONIC ACID.

Mucoid states characterized by the elevated deposition and accumulation of mucin (mucopolysaccharides) in dermal tissue. The fibroblasts are responsible for the production of acid mucopolysaccharides (GLYCOSAMINOGLYCANS) in the ground substance of the connective tissue system. When fibroblasts produce abnormally large quantities of mucopolysaccharides as hyaluronic acid, chondroitin sulfate, or heparin, they accumulate in large amounts in the dermis.

A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.

A therapeutic treatment typically involving INTRA-ARTICULAR INJECTIONS of HYALURONIC ACID and related compounds. The procedure is commonly used in the treatment of OSTEOARTHRITIS with the therapeutic goal to restore the viscoelasticity of SYNOVIAL FLUID, decrease pain, improve mobility and restore the natural protective functions of hyaluronan in the joint.

An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature greying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.

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