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Hyaluronic acid Sanofi - Biotech, Pharma and Life Science Channel

11:43 EDT 1st October 2016 | BioPortfolio

PubMed Articles [7577 Associated PubMed Articles listed on BioPortfolio]

Characterization of the glucansucrase GTF180 W1065 mutant enzymes producing polysaccharides and oligosaccharides with altered linkage composition.

Exopolysaccharides produced by lactic acid bacteria are extensively used for food applications. Glucansucrase enzymes of lactic acid bacteria use sucrose to catalyze the synthesis of α-glucans with d...

Changes of phenolic-acids and vitamin E profiles on germinated rough rice (Oryza sativa L.) treated by high hydrostatic pressure.

This study was performed to investigate changes in the phenolic acid and vitamin E profiles of germinated rough rice following high hydrostatic pressure treatment (HPT). Rough rice was germinated at 3...

Method for the isolation of citric acid and malic acid in Japanese apricot liqueur for carbon stable isotope analysis.

A method for detecting the undeclared addition of acidic ingredients is required to control the authenticity of Japanese apricot liqueur. We developed an analytical procedure that minimizes carbon iso...

Inhibitory effect of chlorogenic acid on digestion of potato starch.

The effect of the chlorogenic acid isomer 5-O-caffeoylquinic acid (5-CQA) on digestion of potato starch by porcine pancreatic alpha amylase (PPAA) was investigated using isolated starch and cooked pot...

Ultrasonication of reconstituted whole milk and its effect on acid gelation.

Ultrasonication (US) of whole milk at 22.5kHz and 50W homogenized fat globules. Extended US without temperature control (attaining >90°C at longest times), or with control at temperatures ⩾60°C ca...

Effects of 24-epibrassinolide on enzymatic browning and antioxidant activity of fresh-cut lotus root slices.

Fresh-cut lotus root slices were treated with 80nM 24-epibrassinolide (EBR) and then stored at 4°C for 8days to investigate the effects on cut surface browning. The results showed that EBR treatment ...

Impact of solid state fermentation on nutritional, physical and flavor properties of wheat bran.

To improve the nutritional, physical and flavor properties of wheat bran, yeast and lactic acid bacteria (LAB) were used for fermenting wheat bran in solid state. Appearance properties, nutritional pr...

Effects of chemical and enzymatic modifications on starch-linoleic acid complex formation.

This study investigated the complexation yield and physicochemical properties of soluble and insoluble starch complexes with linoleic acid when a β-amylase treatment was applied to acetylated and deb...

Kinetics of the incorporation of the main phenolic compounds into the lignan macromolecule during flaxseed development.

The main flax lignan, secoisolariciresinol diglucoside, is stored in a macromolecule containing other ester-bound phenolic compounds. In this study, NMR and HPLC-UV analyses were performed on flaxseed...

Milk from cows grazing on cool-season pastures provides an enhanced profile of bioactive fatty acids compared to those grazed on a monoculture of pearl millet.

The demand for dairy products from grass-fed cows is driven, in part, by their more desirable fatty acid (FA) profile, containing more n-3 FA and conjugated linoleic acids (CLA) than conventionally pr...

News Articles [2182 Associated News Articles listed on BioPortfolio]

Regeneron and Sanofi Announce Positive Dupixent® (dupilumab) Phase 3 Atopic Dermatitis Data Published in the New England Journal of Medicine

TARRYTOWN, N.Y. and PARIS, Oct. 1, 2016 /PRNewswire/ -- Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and Sanofi today announce that detailed results from LIBERTY AD SOLO 1 and SOLO 2, two placebo-co...

Regeneron eczema drug reduces itch and anxiety, two studies show

Oct 1 (Reuters) - Patients taking an experimental eczema drug from Regeneron Pharmaceuticals Inc and Sanofi Inc experienced significant relief in itching and in anxiety and depression symptoms, meeti...

Ciliates Are Genetic-Code Deviants

Traditional stop codons have a double meaning in the protozoans' mRNA, sometimes calling for an amino acid during translation.

Protozoans Found With No Dedicated Stop Codons

Some ciliates use the same trio of nucleotides to code for an amino acid and to stop translation.

Tumour metabolism: Reflecting their origins

Mayers, Torrence et al. show that lung tumours driven by oncogenic KRAS and loss of p53 depend on branched-chain amino acid metabolism, whereas pancreatic tumours driven by the same genetic defects do...

#jobs #lifescience Regional Director, MSL Midwest, MS

// MA-US Remote, Regional Director, MSL Midwest, MS-POS_75079261-1 Description Sanofi Genzyme focuses on developing specialty treatments for debilitating diseases that are often difficult to diagnose ...

Fatty acid-binding protein 1 is preferentially lost in microsatellite instable colorectal carcinomas and is immune modulated via the interferon γ pathway

Sanofi Creates Consumer Unit With Eye To Expansion

Former Bayer executive Alan Main tapped to lead Consumer HealthCare global business unit, which Sanofi will consider expanding through acquisitions...  

Apothederm Skin Care Gifts A Delicious Amount to Customers & Women During Breast Cancer Awareness Month With Partner Bright Pink®

Apothederm®, the skin care line known worldwide for their anti-aging, acne, skin brightening and restoration solutions, will proudly donate 20% of their sales on selected “pink” unisex body/s...

Sanofi Appoints Alan Main to Executive Committee and Executive Vice President, Consumer HealthCare

 Sanofi Appoints Alan Main to Executive Committee and Executive Vice President, Consumer HealthCare Paris, France - September 30, 2016 - Sanofi today announced the appointment of...

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Companies [79 Associated Companies listed on BioPortfolio]

Sanofi Genzyme

WAVE Life Sciences Ltd.

WAVE Life Sciences is utilizing its innovative and proprietary synthetic chemistry drug development platform to design, develop and commercialize stereopure nucleic acid therapeut...

Pronutria Biosciences

Pronutria Biosciences is pioneering new nutritional and therapeutic modalities: amino acid biologics. Amino acids (AA) are known as the “building blocks of life,” and ar...

Alexion Pharmaceuticals Inc.

Alexion is a global biopharmaceutical company focused on developing and delivering life-transforming therapies for patients with devastating and rare disorders. Alexion developed ...

MabSpace Biosciences Co., Ltd.

MabSpace Biosciences Co., Ltd. is a biotechnology company focused on the discovery and early development of antibody based therapeutics. The key advantage of its proprietary immun...

Pronutria Biosciences Inc.

Pronutria Biosciences is pioneering new nutritional and therapeutic modalities: amino acid biologics. Amino acids (AA) are known as the “building blocks of life,” and ar...

Merial

Merial is a world-leading, innovation-driven animal health company that provides a comprehensive range of products to enhance the health, well-being and performance of a wide rang...

Mirus Bio Corporation

Mirus Bio Corporation is a biopharmaceutical company focused on discovering, developing and commercializing innovative nucleic acid based technologies and products. The company currently markets a ran...

Voyager Therapeutics, Inc.

Voyager Therapeutics is a clinical-stage gene therapy company developing life-changing treatments for severe diseases of the central nervous system. Voyager is committed to advanc...

Ontario, Canada

Ontario, Canada’s business environment is designed for global success. Ontario is an efficient North American hub for international investment and trade. It offers direct acc...

Clinical Trials [1871 Associated Clinical Trials listed on BioPortfolio]

Effects of Omega-3 Fatty Acids in Ambient Air Pollution Exposure in Healthy Adults

This observational study recruits healthy individuals who have been routinely taking high amount (at least 3 g/wk) of dietary eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), an...

A Study Evaluating a Proprietary Amino Acid Mixture (Enterade®) in Patients Receiving High-Dose Melphalan Conditioning Followed by Autologous Stem Cell Transplantation for Multiple Myeloma and Non-Hodgkin Lymphoma

This research study is evaluating Enterade, a supplement, as a possible treatment for the side effects caused by Stem Cell Transplant. The following interventions will be involved in this...

Safety and Efficacy Study of Vaccine Schedule With Ad26.Mos.HIV and MVA-Mosaic in Human Immunodeficiency Virus (HIV)-Infected Adults

The purpose of the study is to assess: 1 safety and tolerability of adenovirus serotype 26 (Ad26) prime and Modified Vaccinia Ankara (MVA) boost versus placebo in participants on suppressi...

The Effect of Topical Tranexamic Acid on Postoperative Bleeding and Effusions From Superficial Wounds

After surgical procedures, interventions to reduce postoperative bleeding are of great importance. In this study, the effect will be investigated of administering tranexamic acid, which is...

Hepatitis A Vaccine Dosing Regimens Among Pediatric Rheumatology Patients on Immunosuppressive Therapy

The study is a prospective, single centre, double-blinded randomized controlled trial whose goal is to compare the immune response of a population of immunosuppressed pediatric rheumatolog...

Sucrosomial Iron in Patients With Celiac Disease and IDA

Sucrosomial iron (Sideral® Forte) is a preparation of ferric pyrophosphate conveyed within a phospholipid membrane associated with ascorbic acid, is a new-generation oral iron which shows...

Fuzhenghuayu for Patients With PBC Who Had An Inadequate Response to Ursodeoxycholic Acid

Ursodeoxycholic acid (UDCA) has been the only treatment for PBC approved by US and European drug administrations. Long-term use of UDCA(13—15 mg/kg/day) in patients with PBC improves ser...

Fuzhenghuayu in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis

Ursodeoxycholic acid (UDCA) has been the only treatment for PBC approved by US and European drug administrations. Long-term use of UDCA (13—15 mg/kg/day) in patients with PBC improves se...

Potential Intervention Strategy With Folic Acid and Vitamin B12 in Patients With Schizophrenia

The investigators study aims are: 1. To investigate folate, vitamin B12, and homocysteine levels in patients with schizophrenia. 2. To evaluate the relationships among fol...

Adjunctive Therapy of Andrographolid Sulfonatein Community Acquired Pneumonia

Adjunctive Therapy of AndrographolidSulfonate in Community Acquired Pneumonia: A Multicenter, Randomized,Double-blinded, Placebo Controlled Clinical Trial. The hypothesis is that combinati...

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Medical and Biotech [MESH] Definitions

A group of high molecular weight chondroitin sulfate proteoglycans that form aggregates with HYALURONIC ACID.

Mucoid states characterized by the elevated deposition and accumulation of mucin (mucopolysaccharides) in dermal tissue. The fibroblasts are responsible for the production of acid mucopolysaccharides (GLYCOSAMINOGLYCANS) in the ground substance of the connective tissue system. When fibroblasts produce abnormally large quantities of mucopolysaccharides as hyaluronic acid, chondroitin sulfate, or heparin, they accumulate in large amounts in the dermis.

A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.

A therapeutic treatment typically involving INTRA-ARTICULAR INJECTIONS of HYALURONIC ACID and related compounds. The procedure is commonly used in the treatment of OSTEOARTHRITIS with the therapeutic goal to restore the viscoelasticity of SYNOVIAL FLUID, decrease pain, improve mobility and restore the natural protective functions of hyaluronan in the joint.

An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature greying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.

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