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Hyaluronic acid Sanofi - Biotech, Pharma and Life Science Channel

08:22 EDT 28th July 2016 | BioPortfolio

PubMed Articles [7462 Associated PubMed Articles listed on BioPortfolio]

Micro/Nano Multilayered Scaffolds of PLGA and Collagen by Alternately Electrospinning for Bone Tissue Engineering.

The dual extrusion electrospinning technique was used to fabricate multilayered 3D scaffolds by stacking microfibrous meshes of poly(lactic acid-co-glycolic acid) (PLGA) in alternate fashion to micro/...

New blends of ethylene-butyl acrylate copolymers with thermoplastic starch. Characterization and bacterial biodegradation.

Ethylene-butyl acrylate copolymer (EBA) with 13% of butyl acrylate content was used to produce blends with 10, 30 and 60% of thermoplastic starch (TPS) plasticized with glycerol. Ethylene-acrylic acid...

Structural characterization and antidiabetic activity of a glucopyranose-rich heteropolysaccharide from Catathelasma ventricosum.

Polysaccharides, which are the main bioactive constituents of edible mushrooms, have been shown to have a variety of useful biological activities. In this study, a polysaccharide fraction from the edi...

Fabrication of magnetic hydroxypropyl cellulose-g-poly(acrylic acid) porous spheres via Pickering high internal phase emulsion for removal of Cu(2+) and Cd(2.).

A series of magnetic hydroxypropyl cellulose-g-poly(acrylic acid) porous spheres were prepared via O/W Pickering high internal phase emulsions (HIPEs) integrated precipitation polymerization. The stru...

Mechanically flexible and optically transparent three-dimensional nanofibrous amorphous aerocellulose.

Aerocelluloses are considered as "third generation" aerogels after the silica and synthetic polymer-based ones. However, their brittleness and low optical translucency keep quite narrow their fields o...

Modification mechanism of sesbania gum, and preparation, property, adsorption of dialdehyde cross-linked sesbania gum.

This paper studied the modification mechanism of Sesbania gum (SG) by means of the variations in the numbers of surface hydroxyl groups on the granules, Schiff's agent coloration of aldehyde groups, F...

New studies on basil (Ocimum bacilicum L.) seed gum: Part II-Emulsifying and foaming characterization.

BSG is composed of two major fractions with different molecular weight: PER-BSG (5980kgmol(-1)) and SUPER-BSG (1045kgmol(-1)). In the present work, the emulsifying and foaming properties of BSG and it...

Purification, characterization and anti-proliferation activities of polysaccharides extracted from Viscum coloratum (Kom.) Nakai.

Three polysaccharides, VCP1, VCP2 and VCP3 were isolated from Viscum coloratum (Kom.) Nakai using DEAE-cellulose chromatography. VCP1 (32KDa) was composed of glucose, galactose, arabinose, rhamnose an...

Mutation in West Nile Virus Structural Protein prM during Human Infection.

A mutation leading to substitution of a key amino acid in the prM protein of West Nile virus (WNV) occurred during persistent infection of an immunocompetent patient. WNV RNA persisted in the patient'...

Pharmacokinetics and tissue distribution of five active ingredients of Eucommiae cortex in normal and ovariectomized mice by UHPLC-MS/MS.

1. Pinoresinol di-O-β-d-glucopyranoside (PDG), geniposide (GE), geniposidic acid (GA), aucubin (AN) and chlorogenic acid (CA) are the representative active ingredients in Eucommiae cortex (EC), whi...

News Articles [2203 Associated News Articles listed on BioPortfolio]

Sanofi annonce l’approbation par la FDA d’AdlyxinTM dans le traitement du diabète de type 2 chez l’adulte

Sanofi — Wednesday, July 27th 2016 at 11:44pm UTC Sanofi annonce l’approbation par la FDA d’AdlyxinTM dans le traitement du diabète de type 2 chez l’adulte – AdlyxinTM e...

Anika Reports Second Quarter 2016 Financial Results

Wednesday, July 27th 2016 at 8:05pm UTC Total Revenue Increases 16% Year-over-Year BEDFORD, Mass.–(BUSINESS WIRE)– Anika Therapeutics, Inc. (NASDAQ: ANIK), a global, integrated orthopedic ...

Sanofi gets FDA approval for type-2 diabetes treatment Adlyxin

Sanofi has announced that the US Food and Drug Administration (FDA) has approved Adlyxin (lixisenatide), which is a once-daily mealtime GLP-1 receptor agonist injection. It is indicated as an adjunct ...

How amino acid cysteine combats Huntington's disease

Researchers at Johns Hopkins Medicine report they have identified a biochemical pathway linking oxidative stress and the amino acid cysteine in Huntington's disease. The findings provide a mechanism t...

A novel excitatory network for the control of breathing

Breathing must be tightly coordinated with other behaviours such as vocalization, swallowing, and coughing. These behaviours occur after inspiration, during a respiratory phase termed postinspiration....

Structure of the adenosine A2A receptor bound to an engineered G protein

G-protein-coupled receptors (GPCRs) are essential components of the signalling network throughout the body. To understand the molecular mechanism of G-protein-mediated signalling, solved structures of...

New aliphatic acid amides from Streptomyces maoxianensis sp. nov.

Relative bioavailability of 13C5-folic acid in pectin-coated folate fortified rice in humans using stable isotope techniques

Eli Gilboa, University of Miami, to Present at 7th Non-Coding RNA & RNAi Therapeutics

Boston, MA, July 28, 2016 --(PR.com)-- Eli Gilboa, Professor of Microbiology & Immunology at the University of Miami, will give a presentation on “Oligonucleotide Aptamer Targeted RNA Thera...

FDA Approves Sanofi's Adlyxin For Treatment Of Adults With Type 2 Diabetes

PARIS (dpa-AFX) - Sanofi (SNYNF, SNY) said that the U.S. Food and Drug Administration approved Adlyxin or lixisenatide, a once-daily mealtime GLP-1 receptor agonist injection indicated as an adjun...

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Companies [79 Associated Companies listed on BioPortfolio]

Sanofi Genzyme

WAVE Life Sciences Ltd.

WAVE Life Sciences is utilizing its innovative and proprietary synthetic chemistry drug development platform to design, develop and commercialize stereopure nucleic acid therapeut...

Pronutria Biosciences

Pronutria Biosciences is pioneering new nutritional and therapeutic modalities: amino acid biologics. Amino acids (AA) are known as the “building blocks of life,” and ar...

Alexion Pharmaceuticals Inc.

Alexion is a global biopharmaceutical company focused on developing and delivering life-transforming therapies for patients with devastating and rare disorders. Alexion developed ...

MabSpace Biosciences Co., Ltd.

MabSpace Biosciences Co., Ltd. is a biotechnology company focused on the discovery and early development of antibody based therapeutics. The key advantage of its proprietary immun...

Pronutria Biosciences Inc.

Pronutria Biosciences is pioneering new nutritional and therapeutic modalities: amino acid biologics. Amino acids (AA) are known as the “building blocks of life,” and ar...

Merial

Merial is a world-leading, innovation-driven animal health company that provides a comprehensive range of products to enhance the health, well-being and performance of a wide rang...

Mirus Bio Corporation

Mirus Bio Corporation is a biopharmaceutical company focused on discovering, developing and commercializing innovative nucleic acid based technologies and products. The company currently markets a ran...

Voyager Therapeutics, Inc.

Voyager Therapeutics is a clinical-stage gene therapy company developing life-changing treatments for severe diseases of the central nervous system. Voyager is committed to advanc...

Ontario, Canada

Ontario, Canada’s business environment is designed for global success. Ontario is an efficient North American hub for international investment and trade. It offers direct acc...

Clinical Trials [1799 Associated Clinical Trials listed on BioPortfolio]

Pharmacokinetic, Pharmacodynamic, Safety, and Efficacy Study of Rivaroxaban for Thromboprophylaxis in Pediatric Participants 2 to 8 Years of Age After the Fontan Procedure

The Purpose of this study is to characterize the single and multiple-dose pharmacokinetic (PK) and pharmacokinetic/pharmacodynamic (PK/ PD) profiles after oral rivaroxaban therapy administ...

Evaluation of the Alere i Influenza A&B Nucleic Acid Amplification Versus Xpert Flu/RSV

The rapid and accurate detection of influenza virus in respiratory specimens is required for optimal management of patients with acute respiratory infections. Because of the variability of...

IMG-7289, With and Without ATRA, in Patients With Advanced Myeloid Malignancies

This is a Phase 1 open label study of the dose and duration of an orally administered LSD1 inhibitor, IMG-7289, in patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (...

Ursodeoxycholic Acid for Rhegmatogenous Retinal Detachment

20 patients presenting a rhegmatogenous retinal detachment with more than 4 days of duration will be prospectively included. A single dose of ursodeoxycholic acid will be administered ora...

The Healthy Cookie Study: Understanding How Healthy Cookies Affect Fat in the Blood,

The purpose of this study is to understand how consuming healthy cookies every day for two weeks will affect different types of fat in the blood. Specifically, the overall goal of this stu...

Inappropriate Prescribing of Proton-pump Inhibitor is it Associated With the Burden of Comobidities in Older Patients Over 75 Years Old ?

Proton pump inhibitors (PPIs) are one of the most frequently prescribed classes of drugs in the world and the most effective drugs available to reduce gastric acid secretion. However, stud...

Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children

Trauma is the leading cause of death and disability in children in the United States. The long-term goal of this project is to evaluate the benefits and harms of tranexamic acid (TXA; a dr...

Folinic Acid and Language Impairment in Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder often with life-long consequences that affects young children during critical developmental periods. The Cente...

Exploratory Study of the Effects of Omega-3-acid Ethyl Esters on the Lipid and Lipoprotein Profile in the Blood

The purpose of this study is to explore the effects of 8-week treatment with omega-3-acid ethyl esters on the lipid and lipoprotein profile in the blood in hyperlipidemic patients receivin...

Ascorbic Acid Treatment in Congenital Glucocorticoids and Mineralocorticoids Deficiency Due to NNT Mutation

Nicotinamide nucleotide transhydrogenase (NNT) mutations cause glucocorticoid and mineralocorticoid deficiencies through decreased detoxification of reactive oxygen species (ROS) in adreno...

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Medical and Biotech [MESH] Definitions

A group of high molecular weight chondroitin sulfate proteoglycans that form aggregates with HYALURONIC ACID.

Mucoid states characterized by the elevated deposition and accumulation of mucin (mucopolysaccharides) in dermal tissue. The fibroblasts are responsible for the production of acid mucopolysaccharides (GLYCOSAMINOGLYCANS) in the ground substance of the connective tissue system. When fibroblasts produce abnormally large quantities of mucopolysaccharides as hyaluronic acid, chondroitin sulfate, or heparin, they accumulate in large amounts in the dermis.

A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.

A therapeutic treatment typically involving INTRA-ARTICULAR INJECTIONS of HYALURONIC ACID and related compounds. The procedure is commonly used in the treatment of OSTEOARTHRITIS with the therapeutic goal to restore the viscoelasticity of SYNOVIAL FLUID, decrease pain, improve mobility and restore the natural protective functions of hyaluronan in the joint.

An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature greying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.

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