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Hyaluronic acid Sanofi - Biotech, Pharma and Life Science Channel

01:16 EDT 25th May 2016 | BioPortfolio

PubMed Articles [7401 Associated PubMed Articles listed on BioPortfolio]

Cellulose reinforced nylon-6 nanofibrous membrane: Fabrication strategies, physicochemical characterizations, wicking properties and biomimetic mineralization.

The aim of the present study is to develop a facile, efficient approach to reinforce nylon 6 (N6) nanofibers with cellulose chains as well as to study the effect that cellulose regeneration has on the...

Whiteness improvement of citric acid crosslinked cotton fabrics: H2O2 bleaching under alkaline condition.

Polycarboxylic acids have been employed as formaldehyde-free crosslinking agents in anti-wrinkle treatment for cotton fabrics. Cotton fabrics treated by citric acid (CA) catalyzed with effective catal...

Effects of added oligoguluronate on mechanical properties of Ca - alginate - oligoguluronate hydrogels depend on chain length of the alginate.

The effect of adding shorter alginate fragments highly enriched in α-l-guluronic acid (oligoG) on the Young's modulus of the Ca-induced alginate hydrogels were determined using nanoindentation. Ca-al...

Application of cellulose acetate for controlled release of thymol.

Cellulose acetate (CA) was investigated as a carrier towards development of material with controlled release of thymol as a natural substance with strong antibacterial properties using high pressure t...

Box-Behnken design for extraction optimization, characterization and in vitro antioxidant activity of Cicer arietinum L. hull polysaccharides.

The optimal extraction conditions with a yield of 5.37±0.15% for extraction of polysaccharides from chickpea (Cicer arietinum L.) hull (CHPS) were determined as extraction temperature 99°C, extracti...

Purification, structural characterization and in vitro antioxidant activity of a novel polysaccharide from Boshuzhi.

A novel polysaccharide, designated GCPB-1b, was obtained from the alkaline extract of the submerged fermentation culturing mycelium powder of Boshuzhi, Ganoderma capense. This polysaccharide was purif...

Structural characterization and in vitro antitumor activity of an acidic polysaccharide from Angelica sinensis (Oliv.) Diels.

A water-soluble polysaccharide extracted from the roots of Angelica sinensis (Oliv.) Diels, which is a traditional Chinese medicine herb, was fractioned and purified by Sephadex G-50 gel filtration ch...

Surface patterned pH-sensitive fluorescence using β-cyclodextrin functionalized poly(ethylene glycol).

This paper reports the development of a pH-responsive molecular pattern that shows specific and selective affinity for particular host-guest interactions, and its use as a pH fluorescent sensor. The p...

Properties and in vitro drug release of hyaluronic acid-hydroxyethyl cellulose hydrogels for transdermal delivery of isoliquiritigenin.

In the present study, the properties of hydrogel systems based on hyaluronic acid (HA)-hydroxyethyl cellulose (HEC) were investigated for effective transdermal delivery of isoliquiritigenin (ILTG). Hy...

The effect of maleinized linseed oil (MLO) on mechanical performance of poly(lactic acid)-thermoplastic starch (PLA-TPS) blends.

In this work, poly(lactic acid), PLA and thermoplastic starch, TPS blends (with a fixed content of 30wt.% TPS) were prepared by melt extrusion process to increase the low ductile properties of PLA. Th...

News Articles [2260 Associated News Articles listed on BioPortfolio]

Exclusive: Sanofi to unveil challenge to Medivation's board - sources

(Reuters) - France's Sanofi SA is preparing to name candidates it will put forward to replace the entire board of U.S. cancer drug company Medivation Inc as early as Wednesday, according to people f...

FDA staffers raise concerns about Sanofi's iGlarLixi

Staffers at the US Food and Drug Administration (FDA) have questioned the efficacy of Sanofi’s experimental…

Sanofi's Diabetes Drug Faces Scrutiny from FDA

An early review conducted by The Food and Drug Administration (FDA) of Sanofi’s combination diabetes drug iGlarLixi is raising a number of issues related to safety and efficacy. iGlarLixi, composed...

NANS-mediated synthesis of sialic acid is required for brain and skeletal development

Andrea Superti-Furga, Ron Wevers, Clara van Karnebeek, Luisa Bonafé and colleagues identify mutations in NANS, which encodes the sialic acid synthase, in nine individuals with severe infantile-onset ...

Sanofi's diabetes head Pascale Witz to leave the company

She will be replaced by Peter Guenter as part of an executive reshuffle

Sanofi

Contributions:  Link: Taking the Long View: Interview with Pascale Witz

Sanofi diabetes chief to leave company as US business struggles

Competition and a tougher payer environment have led to lower sales from the important diabetes division. 

US FDA advisors question usefulness of Sanofi's combination diabetes therapy

US Food and Drug Administration staff questioned the benefits of French drugmaker Sanofi's (Euronext: SAN) diabetes drug candidate as well as raised doubts over the results of clinical trials showing ...

More Light On Cancer: Scientists Created Nanoparticles To Highlight Cancer Cells

Investigations to find methods for synthesizing such nanoparticles are actively conducted in many laboratories around the world, however, according to one of the study co-authors, professor of the Phy...

Sanofi's 2-Pen Diabetes Combo Perplexes FDA

Sanofi SA's strategy of using two pen injectors for its fixed-ratio combination that combines its experimental glucagon-like peptide-1 receptor agonist...   

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Companies [79 Associated Companies listed on BioPortfolio]

Sanofi Genzyme

WAVE Life Sciences Ltd.

WAVE Life Sciences is utilizing its innovative and proprietary synthetic chemistry drug development platform to design, develop and commercialize stereopure nucleic acid therapeut...

Pronutria Biosciences

Pronutria Biosciences is pioneering new nutritional and therapeutic modalities: amino acid biologics. Amino acids (AA) are known as the “building blocks of life,” and ar...

Alexion Pharmaceuticals Inc.

Alexion is a global biopharmaceutical company focused on developing and delivering life-transforming therapies for patients with devastating and rare disorders. Alexion developed ...

MabSpace Biosciences Co., Ltd.

MabSpace Biosciences Co., Ltd. is a biotechnology company focused on the discovery and early development of antibody based therapeutics. The key advantage of its proprietary immun...

Pronutria Biosciences Inc.

Pronutria Biosciences is pioneering new nutritional and therapeutic modalities: amino acid biologics. Amino acids (AA) are known as the “building blocks of life,” and ar...

Merial

Merial is a world-leading, innovation-driven animal health company that provides a comprehensive range of products to enhance the health, well-being and performance of a wide rang...

Mirus Bio Corporation

Mirus Bio Corporation is a biopharmaceutical company focused on discovering, developing and commercializing innovative nucleic acid based technologies and products. The company currently markets a ran...

Voyager Therapeutics, Inc.

Voyager Therapeutics is a clinical-stage gene therapy company developing life-changing treatments for severe diseases of the central nervous system. Voyager is committed to advanc...

Ontario, Canada

Ontario, Canada’s business environment is designed for global success. Ontario is an efficient North American hub for international investment and trade. It offers direct acc...

Clinical Trials [1727 Associated Clinical Trials listed on BioPortfolio]

Role of Tranexamic Acid Versus Uterine Cooling at Caesarean Section

This study aims to compare role of a prophylactic predefined intravenous Tranexamic Acid dose versus intraoperative Uterine Cooling in reducing blood loss and incidence of postpartum hemor...

Vaccine Therapy in Preventing Cancer Recurrence in Patients With Non-Metastatic, Node Positive, HER2 Negative Breast Cancer That is in Remission

This phase I trial studies the side effects and best dose of a vaccine therapy in preventing cancer from coming back in patients with non-metastatic, node positive, human epidermal growth ...

Gestational Diabetes Mellitus and Neurodevelopment in Newborns

The purpose of this study is to evaluate the feasibility of using a quantitative EEG method to evaluate neurodevelopment in newborns and to evaluate whether subtle neurodevelopmental defic...

Steroids, Hyaluronic Acid or Platelet Rich Plasma Versus Placebo for the Knee Osteoarthritis

This study investigates clinical outcome and imaging outcome parameters after intraarticular injection of steroids, platelet-rich-plasma (prp), hyaluronic acid or placebo in patients with ...

UCMSC Transplantation in the Treatment of Cartilage Damage

The purpose of this study is to investigate the efficacy and safety of transplantation of umbilical cord mesenchymal stem cells(UCMSCs) in patient with Knee cartilage damage.

Safety and Immunogenicity of IPOVAC in Young Children

A dose escalating study with 3 different dosing regimens of the studied vaccine (IPOVAC- POLYVAC-Vietnam) and a licensed vaccine (IMOVAC-Sanofi Pasteur- France) is conducted in Vietnamese ...

Clinical Study to Assess the Equivalence of Tranexamic Acid vs Oxytocin in Reducing the PPH

The purpose of this study was to evaluate that the tranexamic acid (TXA)Intravenous and oral, is equivalent oxytocin (OXY),intramuscularly, in reducing the blood loss in post partum period...

Does Ultrasound-guided Suprascapular Nerve Block Provide Additional Benefit Over Traditional Rehabilitation Program for Patients With Chronic Shoulder Pain

This study was conducted to compare the efficacy of hydrodilatation with hyaluronic acid under ultrasonographic guidance plus physical therapy (PT) with that of PT alone for treating adhes...

Citrulline Challenge Study for Healthy Subjects in the United Kingdom

There are many forms of small bowel disease but their direct consequences on small bowel function are often very hard, if not impossible, to establish. It would be helpful if there was a r...

The Effect of Guardix-solution for the Prevention of Postoperative Intestinal Adhesion and Intestinal Obstruction After Laparoscopic Pelvic Cavity Surgery: Randomized, Prospective, Multicenter Study

To assess the anti-adhesive effect of treatment with hyaluronic acid-carboxymethylcellulose following laparoscopic pelvic surgery (radical prostatectomy).

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Medical and Biotech [MESH] Definitions

A group of high molecular weight chondroitin sulfate proteoglycans that form aggregates with HYALURONIC ACID.

Mucoid states characterized by the elevated deposition and accumulation of mucin (mucopolysaccharides) in dermal tissue. The fibroblasts are responsible for the production of acid mucopolysaccharides (GLYCOSAMINOGLYCANS) in the ground substance of the connective tissue system. When fibroblasts produce abnormally large quantities of mucopolysaccharides as hyaluronic acid, chondroitin sulfate, or heparin, they accumulate in large amounts in the dermis.

A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.

A therapeutic treatment typically involving INTRA-ARTICULAR INJECTIONS of HYALURONIC ACID and related compounds. The procedure is commonly used in the treatment of OSTEOARTHRITIS with the therapeutic goal to restore the viscoelasticity of SYNOVIAL FLUID, decrease pain, improve mobility and restore the natural protective functions of hyaluronan in the joint.

An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature greying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.

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