Hyaluronic acid Sanofi - Biotech, Pharma and Life Science Channel

15:53 EST 1st March 2015 | BioPortfolio

PubMed Articles [7056 Associated PubMed Articles listed on BioPortfolio]

Enhancement of a Novel Extracellular Uricase Production by Media Optimization and Partial Purification by Aqueous Three-Phase System.

Uricase (urate: oxygen oxidoreductase, EC 1.7.3.3), an enzyme belonging to the class of oxidoreductases, catalyzes the enzymatic oxidation of uric acid to allantoin and finds a wide variety of applica...

Molecular Cloning, Sequence, and Phylogenetic Analysis of T Helper 1 Cytokines of Pashmina Goats.

Cytokines play an important role in regulation of immune responses either in health or disease. In the present study, the cDNAs encoding mature Interleukin (IL)-2, interferon gamma (IFN-γ), and IL-12...

Influence of DGAT1 K232A Polymorphism on Milk Fat Percentage and Fatty Acid Profiles in Romanian Holstein Cattle.

Milk and dairy products are considered the main sources of saturated fatty acids, which are a valuable source of nutrients in the human diet. Fat composition can be adjusted through guided nutrition o...

Towards the fabrication of artificial 3D microdevices for neural cell networks.

This work reports first steps towards the development of artificial neural stem cell microenvironments for the control and assessment of neural stem cell behaviour. Stem cells have been shown to be fo...

Enhanced survival and engraftment of transplanted stem cells using growth factor sequestering hydrogels.

We have generated a bioinspired tunable system of hyaluronic acid (HyA)-based hydrogels for Matrix-Assisted Cell Transplantation (MACT). With this material, we have independently evaluated matrix para...

Exploring strategies for classification of external stimuli using statistical features of the plant electrical response.

Plants sense their environment by producing electrical signals which in essence represent changes in underlying physiological processes. These electrical signals, when monitored, show both stochastic ...

Zinc Accumulation and Tolerance in Solanum nigrum are Plant Growth Dependent.

Zinc tolerance, accumulation, and organic acid production by Solanum nigrum, a known Zn accumulator, was studied during pre- and post-flowering stages of development. The plants, when challenged with ...

Hyperaccumulator Oilcake Manure as an Alternative for Chelate-Induced Phytoremediation of Heavy Metals Contaminated Alluvial Soils.

The ability of hyperaccumulator oilcake manure as compared to chelates was investigated by growing Calendula officinalis L for phytoremediation of cadmium and lead contaminated alluvial soil. The comb...

Negative Effects of Chelants on Soil Qualities of Five Soil Series.

Due to the low phytoavailability of some heavy metals (HMs), a prolonged period is required when phytoextraction is used to remove these HMs from contaminated soils. The use of chelants and other chem...

Using Contaminated Plants Involved in Phytoremediation for Anaerobic Digestion.

This study investigated the anaerobic digestion capability of five plants and the effects of copper (Cu) and S,S'-ethylenediaminedisuccinic acid (EDDS, a chelator widely used in chelant-assisted phyto...

News Articles [2036 Associated News Articles listed on BioPortfolio]

BioNotebook: Former Sanofi CEO Viehbacher joins PureTech board; three venture financings, four deals and a dropped drug

It didn't take long for Chris Viehbacher to jump back in to the world of drug development, although by joining the board of directors of PureTech in Boston he's swimming at the opposite end of the bio...

The AAPS Journal: Pentylindole/Pentylindazole Synthetic Cannabinoids and Their 5-Fluoro Analogs Produce Different Primary Metabolites: Metabolite Profiling for AB-PINACA and 5F-AB-PINACA

Type: Original PaperWhereas non-fluoropentylindole/indazole synthetic cannabinoids appear to be metabolized preferably at the pentyl chain though without clear preference for one specific position, th...

Monthly News Roundup - February 2015

Sanofi Receives FDA Approval for Basal Insulin Toujeo The U.S. Food and Drug Administration has approved Sanofi’s Toujeo (insulin glargine [rDNA origin], a once-daily long-acting basal insulin for ...

BIO Accepting Nominations for its Award Honoring One Outstanding Woman in Industrial Biotech

Today, BIO announced that it has officially extended its deadline for the Rosalind Franklin Award for Leadership in Industrial Biotechnology. In its second year, the BIO Rosalind Franklin Award was c...

AstraZeneca options rights to Orca's ROR gamma T projects

AstraZeneca PLC and Orca Pharmaceuticals Ltd. signed a three-year deal to further develop Orca’s retinoic acid-related orphan nuclear receptor gamma (ROR gamma T or RORy) inhibitors for autoimmune d...

Eddingpharm gains Chinese rights to Amarin's Vascepa

Amarin Corp. plc (NASDAQ:AMRN) granted Eddingpharm Inc. (Shanghai, China) exclusive rights to hypertriglyceridemia drug Vascepa icosapent ethyl in Greater China.Amarin will receive $15 million up fron...

Viehbacher joins PureTech's board

PureTech Ventures (Boston, Mass.) named former Sanofi (Euronext:SAN; NYSE:SNY) CEO Christopher Viehbacher to its board.PureTech CEO and Managing Partner Daphne Zohar said the board is involved in choo...

Former Sanofi CEO Joins Puretech’s Board of Directors

PureTech, a science and technology R&D company focused  on identifying, inventing and commercializing disruptive products and technologies in the healthcare sector, announced today the appointmen...

CORRECTED-Sacked Sanofi boss joins PureTech board

PARIS, Feb 27 (Reuters) - Chris Viehbacher, sacked as chief executive of French drugs firm Sanofi last year, is to join the board of PureTech, a privately owned healthcare science and technology R&D c...

Ousted Sanofi boss finds role at PureTech

US science and technology R&D company PureTech has appointed the former Sanofi chief executive Christopher Viehbacher to its board. Viehbacher had been ejected from his role after the French firm...

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Companies [68 Associated Companies listed on BioPortfolio]

Anika Therapeutics Incorporated

Anika Therapeutics, Inc. develops, manufactures and commercializes therapeutic products and devices intended to repair, protect and heal bone, cartilage and soft tissues. These products are currently ...

CanBiocin Inc

CanBiocin was formed in 1998 as a University of Alberta spin-off company to commercialize novel technologies developed from research conducted by professors Michael Stiles, Lynn M...

WaVe Life Sciences

WaVe Life Sciences is leading a revolution in nucleic acid therapeutics and was founded on the core principle that medicines should possess precisely controlled molecular structur...

QIAGEN

QIAGEN is one of the world’s leading providers of innovative enabling technologies and products for separating and purifying nucleic acids (DNA and RNA). Since 1986, the Company has developed and ma...

TapImmune Inc.

TapImmune Inc. is an immunotherapy company specializing in the development of innovative vaccine technologies for the treatment of cancer and infectious disease. The Company’...

Creative Biogene

Creative Biogene provides kits, reagents, and services that help researchers explore questions about gene discovery, regulation, and function. Creative Biogene holds a leadership position in the glo...

Reinnervate Ltd

Reinnervate is a market leading company in the fast growing 3D cell culture market. The Alvetex® family of 3D cell culture products provide a flexible platform that allows scientists in any life...

Oasis Diagnostics Corporation

Oasis Diagnostics® is an emerging Vancouver, WA based company focused on the design, development and commercialization of salivary diagnostic tools with applications at the poi...

ImmunID

ImmunID is pioneering the field of molecular immune diagnostics since 2005, offering two commercial products. Its proprietary CE-marked flagship product ImmunTraCkeR evaluates the...

Axiall Corporation

Axiall Corporation is a leading integrated chemicals and building products company. It is an international manufacturer of chlor-alkali and derivatives, chlorovinyls and aromatics...

Clinical Trials [1307 Associated Clinical Trials listed on BioPortfolio]

A Phase II Study of Doxorubicin, Cyclophosphamide and Vindesine With Valproic Acid in Patients With Refractory or Relapsing Small Cell Lung Cancer After Platinum Derivatives and Etoposide

The primary aim of this study is to determine if the addition of valproic acid to a combination of adriamycin, cyclophosphamide and vindesine could increase progression-free survival in pa...

Study of the Poly (ADP-ribose) Polymerase-1 (PARP-1) Inhibitor BSI-201 in Patients With Newly Diagnosed Malignant Glioma

The phase I portion of study is designed to determine the Maximum Tolerated Dose (MTD) of BSI-201 with two clinically relevant dosing regimens of temozolomide (TMZ). Secondary objectives ...

A Study of Azelaic Acid (AzA) 15% in Topical Treatment of Mild to Moderate Perioral Dermatitis

The purpose of this study is to test the efficacy and safety of AzA 15% Gel in the treatment of mild to moderate perioral dermatitis.

Intermittent or Continuous Acetylsalicylic Acid and Gene Expression in the Nasal Tissue of Current Smokers

This randomized phase II trial studies the safety and effects of acetylsalicylic acid (aspirin) taken continuously or intermittently on gene expression in the nasal tissue of current smoke...

Bioavailability of Phenolic Compounds in Bread

The consumption of wholemeal cereals has been associated with the reduction of several chronic diseases. The mechanisms behind these protective effects may be linked, besides dietary fiber...

The Diagnostic Validity of the Urea Breath Test

1. To compare the diagnostic accuracy of the 13C-Urea breath test between using the citric acid as test meal and controlled group by endoscopic biopsy methods(histology, CLOtest...

A Phase I/II to Assess Safety, Tolerability and Efficacy of DL-lactic Acid Syrup in Children With Recurrent Tonsillitis

The study objectives are to evaluate Tonsitin™ (10% Lactic Acid) safety, tolerability and preliminary efficacy, as a potent treatment for Recurrent Tonsillitis in children.

Interest of Ascorbic Acid in the Management of Pneumonia in Elderly People Hospitalized.

Pneumonia is the second common infection and its risk increases for elderly. In this population, it is the first cause of mortality by infections, and source of many complications. Geriatr...

Safety and Efficacy Study of Sebelipase Alfa in Patients With Lysosomal Acid Lipase Deficiency

This study will evaluate the safety and efficacy of sebelipase alfa in a broad population of patients with lysosomal acid lipase deficiency (LALD).

Effects of an Amino Acid and Chromium-picolinate Containing Drink on Glucose Metabolism

It has previously been shown in healthy overweight subjects, that table water including a defined amount of amino acids and chromium can decrease the postprandial glucose and insulin respo...

Medical and Biotech [MESH] Definitions

A group of high molecular weight chondroitin sulfate proteoglycans that form aggregates with HYALURONIC ACID.

Mucoid states characterized by the elevated deposition and accumulation of mucin (mucopolysaccharides) in dermal tissue. The fibroblasts are responsible for the production of acid mucopolysaccharides (GLYCOSAMINOGLYCANS) in the ground substance of the connective tissue system. When fibroblasts produce abnormally large quantities of mucopolysaccharides as hyaluronic acid, chondroitin sulfate, or heparin, they accumulate in large amounts in the dermis.

A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.

A therapeutic treatment typically involving INTRA-ARTICULAR INJECTIONS of HYALURONIC ACID and related compounds. The procedure is commonly used in the treatment of OSTEOARTHRITIS with the therapeutic goal to restore the viscoelasticity of SYNOVIAL FLUID, decrease pain, improve mobility and restore the natural protective functions of hyaluronan in the joint.

An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature greying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.

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