Hyaluronic acid Sanofi - Biotech, Pharma and Life Science Channel

12:00 EDT 28th May 2015 | BioPortfolio

PubMed Articles [7144 Associated PubMed Articles listed on BioPortfolio]

Enhancement of a Novel Extracellular Uricase Production by Media Optimization and Partial Purification by Aqueous Three-Phase System.

Uricase (urate: oxygen oxidoreductase, EC 1.7.3.3), an enzyme belonging to the class of oxidoreductases, catalyzes the enzymatic oxidation of uric acid to allantoin and finds a wide variety of applica...

Comparative in vitro fermentations of cranberry and grape seed polyphenols with colonic microbiota.

In this study, we have assessed the phenolic metabolism of a cranberry extract by microbiota obtained from the ascending colon and descending colon compartments of a dynamic gastrointestinal simulator...

Ion-exchange equilibrium of N-acetyl-d-neuraminic acid on a strong anionic exchanger.

N-acetyl-d-neuraminic acid (Neu5Ac) is a high value-added product widely applied in the food industry. A suitable equilibrium model is required for purification of Neu5Ac based on ion-exchange chromat...

5-Methoxytryptamine reacts with natural food flavour to produce 6-methoxy tetrahydro-β-carbolines: In vitro investigation of their antioxidant and cytotoxicity properties.

Various 6-methoxytetrahydro-β-carboline derivatives, namely BEN (6-methoxy-1-phenyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole), ANI (6-methoxy-1-(4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]i...

Chemical composition of red, brown and green macroalgae from Buarcos bay in Central West Coast of Portugal.

Six representative edible seaweeds from the Central West Portuguese Coast, including the less studied Osmundea pinnatifida, were harvested from Buarcos bay, Portugal and their chemical characterizatio...

Antioxidant activity of alkyl gallates and glycosyl alkyl gallates in fish oil in water emulsions: Relevance of their surface active properties and of the type of emulsifier.

The antioxidant activity of gallic acid and a series of alkyl gallates (C4-C18) and glycosylated alkyl gallates (C4-C18) on fish oil-in-water emulsions was studied. Three types of emulsifiers, lecithi...

Influence of dried Hokkaido pumpkin and ascorbic acid addition on chemical properties and colour of corn extrudates.

The influence of Hokkaido pumpkin powder (PP) addition to corn grits at levels 4%, 6%, and 8% and ascorbic acid (AA) addition at levels 0.5% and 1% was evaluated. Extrusion was done using a single-scr...

Three differently generated salmon protein hydrolysates reveal opposite effects on hepatic lipid metabolism in mice fed a high-fat diet.

This study investigates the effects of salmon peptide fractions, generated using different enzymatic hydrolyzation methods, on hepatic lipid metabolism. Four groups of mice were fed a high-fat diet wi...

Variation in nutritional compositions, antioxidant activity and microstructure of Lycopus lucidus Turcz. root at different harvest times.

The objective of this study was to investigate the variation in nutritional compositions, antioxidant activity and microstructure of Lycopus lucidus Turcz. root at different harvest times. L. lucidus ...

Physical features, phenolic compounds, betalains and total antioxidant capacity of coloured quinoa seeds (Chenopodium quinoa Willd.) from Peruvian Altiplano.

Physical features, bioactive compounds and total antioxidant capacity (TAC) of coloured quinoa varieties (Chenopodium quinoa Willd.) from Peruvian Altiplano were studied. Quinoa seeds did not show a p...

News Articles [1947 Associated News Articles listed on BioPortfolio]

Evotec-Aktie: Sanofi-Deal lädt zum Träumen ein und lässt Bewertung steigen! - Aktienanalyse

London - Evotec-Aktienanalyse der Analysten Dr. Mick Cooper und Dr. Philippa Gardner von Edison Investment Research: Im Rahmen einer aktuellen Aktienanalyse bestätigt Igor Kim, Aktienanalyst von Od.....

Sanofi Announces Men With Advanced Prostate Cancer in England Will Continue to Have Access to Cabazitaxel (Jevtana®)

GUILDFORD, England, May 28, 2015 /PRNewswire/ -- - Sanofi works with NHS England on interim agreement until NICE re-appraisal - Sanofi announced today that it has reached agreement with NHS Englan...

Retrophin leaps on plan to sell Priority Review Voucher to Sanofi

Retrophin has agreed to sell its Rare Pediatric Disease Priority Review Voucher to French pharma major…

Evotec (EVT) - A deal to dream for and key data due soon

Edison Investment Research - Pharmaceutical & Healthcare - Evotec: The exceptional deal with Sanofi for its Toulouse facility at no cost provides Evotec with a platform to accelerate its growth. Evote...

Pronutria Biosciences Raises $39 Million in Series C Financing

Proceeds will Advance Clinical Development Programs for Multiple Therapeutic Areas Pronutria Biosciences, a clinical stage biotechnology company pioneering a new class ...

Sanofi pays $245m for FDA priority review voucher

PRV reduces review time from ten to six months

Alpha-l-Fucosidase Isoenzyme iso2 from Paenibacillus thiaminolyticus

Background: α-l-Fucosidases are enzymes involved in metabolism of α-l-fucosylated molecules, compounds with a fundamental role in different life essential processes including immune response, fertil...

Influence of oxygen deficiency and the role of specific amino acids in cryopreservation of garlic shoot tips

Background: Garlic has lost its ability to form seeds in the course of its domestication. Therefore, the germplasm storage via cryopreservation is increasingly applied. The progression of the various ...

Rosa & Co. Announces Multi-Year, World-Wide PhysioPD™ Research Agreement with Sanofi

SAN CARLOS, Calif., May 28, 2015 /PRNewswire/ -- Rosa & Co. LLC, a drug development advisory firm with expertise in drug-disease modeling and simulation, today announced the initiation of a m...

Sanofi Appoints Suresh Kumar to the Executive Committee and Executive Vice President, External Affairs

Sanofi announced the appointment of Suresh Kumar as a new member of the Executive Committee, effective June 1, 2015. Mr. Kumar joins Sanofi from Oliver Wyman and will take the position of Executive Vi...

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Companies [72 Associated Companies listed on BioPortfolio]

Ontario, Canada

Ontario, Canada’s business environment is designed for global success. Ontario is an efficient North American hub for international investment and trade. It offers direct acc...

MabSpace Biosciences Co., Ltd.

MabSpace Biosciences Co., Ltd. is a biotechnology company focused on the discovery and early development of antibody based therapeutics. The key advantage of its proprietary immun...

Leisure Care

Leisure Care, LLC is one of the largest privately owned and most innovative operators of senior living communities in the United States and Canada. Founded in 1976, Leisure Care o...

ImmunoGen, Inc.

ImmunoGen, Inc. develops targeted anticancer therapeutics using its expertise in cancer biology, monoclonal antibodies and the creation and attachment of potent cell-killing agent...

Anika Therapeutics Incorporated

Anika Therapeutics, Inc. develops, manufactures and commercializes therapeutic products and devices intended to repair, protect and heal bone, cartilage and soft tissues. These products are currently ...

CanBiocin Inc

CanBiocin was formed in 1998 as a University of Alberta spin-off company to commercialize novel technologies developed from research conducted by professors Michael Stiles, Lynn M...

WaVe Life Sciences

WaVe Life Sciences is leading a revolution in nucleic acid therapeutics and was founded on the core principle that medicines should possess precisely controlled molecular structur...

QIAGEN

QIAGEN is one of the world’s leading providers of innovative enabling technologies and products for separating and purifying nucleic acids (DNA and RNA). Since 1986, the Company has developed and ma...

TapImmune Inc.

TapImmune Inc. is an immunotherapy company specializing in the development of innovative vaccine technologies for the treatment of cancer and infectious disease. The Company’...

Creative Biogene

Creative Biogene provides kits, reagents, and services that help researchers explore questions about gene discovery, regulation, and function. Creative Biogene holds a leadership position in the glo...

Clinical Trials [1388 Associated Clinical Trials listed on BioPortfolio]

Dexlansoprazole Delayed-Release Capsules for Acid-Related Disorders in Infants Aged 1 to 11 Months

The purpose of this study is to assess the pharmacokinetics (PK) and pharmacodynamics (PD) [after daily administration for 7 days] and safety [after daily administration for 8 weeks] of de...

Study to Evaluate the Protective Effect of α-Keto Acid With Low-protein Diet on Renal Function in PD Patients

This randomized, open-label, prospective study will evaluate the renal effective effect of compound α-Keto Acid plus low protein diet in PD Patients.

Studying DNA in Blood and Bone Marrow Samples From Younger Patients With Acute Myeloid Leukemia

This research trial studies deoxyribonucleic acid (DNA) in blood or bone marrow samples from younger patients with acute myeloid leukemia. Studying samples of blood and bone marrow from pa...

Effect of Reducing Uric Acid on Insulin Sensitivity and Oxidative Status

The purpose of this study is to learn more about what is the effect of uric acid on oxidative stress and on the way the body metabolizes sugar in obese people. Understanding this may lead ...

Impact of High-dose Folic Acid Supplementation on Pathways Linked to DNA Formation

Periconceptional supplementation with folic acid - the synthetic form of the B-vitamin folate - reduces the occurrence of adverse pregnancy outcomes such as spina bifida. The underlying bi...

Irinotecan Hydrochloride and Veliparib in Treating Patients With Cancer That Is Metastatic or Cannot Be Removed by Surgery

This phase I trial studies the side effects and best dose of veliparib when given together with irinotecan hydrochloride in treating patients with cancer that has spread to other parts of ...

H7N9 Mix and Match With MF59 in Healthy Elderly Persons

This is a Phase II randomized, partially-blinded, controlled trial in 360 (up to 600) males and females, 65 years of age and older, who are in good health and meet all eligibility criteria...

A Study to Investigate How Common Pancreatic Exocrine Insufficiency (PEI) is in Patients With Type 2 Diabetes and Also to Investigate the Uptake of a Single Dose of EPANOVA® or OMACOR® in Patients With Different Degrees of PEI

This study is a 2-part open-label, randomized, crossover, multicenter, non-therapeutic Phase II study to investigate the presence of pancreatic exocrine insufficiency (PEI) in patients wit...

Studying Genes in Samples From Younger Patients With Desmoplastic Small Round Cell Tumor Registered on COG-D9902 or COG-ABTR01B1

RATIONALE: Studying samples of blood and tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers relate...

Prospects for the Prevention of Pregnancy-induced Hypertension and Preeclampsia Trial

Hypertensive disorders of pregnancy (HDP) are with 50.000 deaths every year one of the major causes of maternal mortality worldwide, especially in low and middle income countries. This tri...

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Medical and Biotech [MESH] Definitions

A group of high molecular weight chondroitin sulfate proteoglycans that form aggregates with HYALURONIC ACID.

Mucoid states characterized by the elevated deposition and accumulation of mucin (mucopolysaccharides) in dermal tissue. The fibroblasts are responsible for the production of acid mucopolysaccharides (GLYCOSAMINOGLYCANS) in the ground substance of the connective tissue system. When fibroblasts produce abnormally large quantities of mucopolysaccharides as hyaluronic acid, chondroitin sulfate, or heparin, they accumulate in large amounts in the dermis.

A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.

A therapeutic treatment typically involving INTRA-ARTICULAR INJECTIONS of HYALURONIC ACID and related compounds. The procedure is commonly used in the treatment of OSTEOARTHRITIS with the therapeutic goal to restore the viscoelasticity of SYNOVIAL FLUID, decrease pain, improve mobility and restore the natural protective functions of hyaluronan in the joint.

An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature greying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.

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