Hypothalamic Controls - Biotech, Pharma and Life Science Channel

17:57 EDT 7th July 2015 | BioPortfolio

PubMed Articles [4268 Associated PubMed Articles listed on BioPortfolio]

Immune Tolerance Induction against Experimental Autoimmune Encephalomyelitis (EAE) Using A New PLP-B7AP Conjugate that Simultaneously Targets B7/CD28 Costimulatory Signal and TCR/MHC-II Signal.

Most of the current therapies used in the treatment of multiple sclerosis (MS) are either ineffective or have adverse side effects. As such, there is a need to develop better therapies that specifical...

Electrically stimulated osteogenesis on Ti-PPy/PLGA constructs prepared by laser-assisted processes.

This work describes a versatile laser-based protocol for fabricating micro-patterned, electrically conductive titanium-polypyrrole/poly(lactic-co-glycolic)acid (Ti-PPy/PLGA) constructs for electricall...

Incorporation of antimicrobial peptides on functionalized cotton gauzes for medical applications.

A large group of low molecular weight natural compounds that exhibit antimicrobial activity has been isolated from animals and plants during the past two decades. Among them, peptides are the most wid...

Emotional effect on cognitive control in implicit memory tasks in patients with schizophrenia.

The aim of this study was to reveal a potential effect of emotion on cognitive control in the implicit memory task with emotionally neutral and unpleasant words in healthy controls and patients with s...

Increased serum levels of brain-derived neurotrophic factor in autism spectrum disorder.

The aim of this study was to investigate the potential role of brain-derived neurotrophic factor (BDNF) in children with autism spectrum disorders (ASD) by measuring serum circulating levels of BDNF a...

Effect of a carbonated HAP/β-glucan composite bone substitute on healing of drilled bone voids in the proximal tibial metaphysis of rabbits.

A novel elastic hydroxyapatite-based composite of high surgical handiness has been developed. Its potential application in orthopedics as a filler of bone defects has been studied. The biomaterial was...

Impact of immunosuppressive therapy on hepatitis B vaccination in inflammatory bowel diseases.

The vaccination rate against hepatitis B virus (HBV) is low in inflammatory bowel disease (IBD) patients. The Consensus from the European Crohn's and Colitis Organisation on opportunistic infections r...

IL-10 gene polymorphism and influence of chemotherapy on cytokine plasma levels in childhood acute lymphoblastic leukemia patients: IL-10 polymorphism and plasma levels in leukemia patients.

Acute Lymphoblastic Leukemia is the leading form of cancer in infancy, and compelling evidences suggest an involvement of altered immune competence on this malignancy pathogenesis. Interleukin 10 (IL-...

Proinflammatory and proosteoclastogenic potential of peripheral blood mononuclear cells from Gaucher patients: Implication for bone pathology.

Gaucher disease (GD) is caused by mutations in the GBA gene that confer a deficient level of activity of glucocerebrosidase (GCase). This deficiency leads to the accumulation of the glycolipid glucoce...

Alpha hemoglobin stabilizing protein: Its causal relationship with the severity of beta thalassemia.

Thalassemia major is characterized by anemia, iron overload and cellular damage. The severity of symptoms correlates with the alpha/non-alpha globin imbalance and is proportional to the magnitude of a...

News Articles [504 Associated News Articles listed on BioPortfolio]

A sexually dimorphic hypothalamic response to chronic high-fat diet consumption

The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1

Abnormal accumulation of triglycerides in the liver, caused in part by increased de novo lipogenesis, results in non-alcoholic fatty liver disease and insulin resistance. Sterol regulatory element-bin...

BioTek Synergy Neo2 Multi-Mode Reader

BioTek has announced the release of the Synergy Neo2 Multi-Mode Reader. The plate reader is designed for speed and ultrahigh performance, incorporating BioTek’s Hybrid Technology with independent op...

New research uncovers brain circuit in fruit fly that detects anti-aphrodisiac

(University of Hawaii at Manoa) New research, published today in eLife from a researcher at the University of Hawai'i -- Mānoa and colleagues, identified the neural circuit in the brain of the fr...

Study reveals brain network responsible for cognitive changes in multiple sclerosis

(Center for BrainHealth ) New findings published today in Neuropsychology reveal that decreased connectivity between network-specific brain regions are to blame for the central deficit common to the v...

Paul Zikmund Named Rite Aid Group Vice President, Risk and Controls

Rite Aid Corporation (NYSE: RAD) announced today that Paul Zikmund, a risk management professional with nearly 30 years of experience, is joining Rite Aid as group vice president ...

Dental pulp cell transplants help regenerate peripheral nerves

(Cell Transplantation Center of Excellence for Aging and Brain Repair) Researchers transplanted mobilized dental pulp stem cells into laboratory rats with sciatic nerve defects to investigate the rege...

US Air Purifiers to Introduces Field Controls Trio Portable Air Purifier

US Air Purifiers will now be carrying the Field Controls Trio 1000P portable air purifier. The TRIO 1000P is time-tested, proven technology all wrapped up in a new innovated user-friendly design. To p...

Study Reignites Calls for Worldwide Controls on Sugary Drinks

Asking patients about what they eat and drink is as important as questioning them about smoking habits, say the authors of a newly published study that highlights the need for urgent global action...

TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms

Terminal uridylyl transferases (TUTs) function as integral regulators of microRNA (miRNA) biogenesis. Using biochemistry, single-molecule, and deep sequencing techniques, we here investigate the mecha...

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Companies [38 Associated Companies listed on BioPortfolio]

Indigo-Clean

Indigo-Clean is an affiliate of Kenall Manufacturing, which has earned a reputation for superior quality, innovation, sustainability and exceptional value in the lighting industry...

Intermatic Incorporated

Intermatic has delivered quality products and service to its customers for over 100 years. As a leading manufacturer of controls and energy-management solutions for electrical, HV...

Xamin, Inc.

Founded in 1999, Xamin, Inc. is a Chicago based company offering industry leading IT services to financial institutions as well as other highly regulated industries. The company p...

NanoSpeed Diagnostics, Inc.

DiaSys Diagnostic Systems is a leading specialist in the development and manufacturing of diagnostic system solutions of highest quality, trusted by customers in more than 100 cou...

Phytecs

Phytecs develops healthcare and nutrition products targeting the endocannabinoid system responsible for the regulation of nearly every physiologic process within the human ...

Digital Lumens

Digital Lumens is a global supplier of enterprise-scale intelligent LED lighting to commercial and industrial customers, delivering 90% energy savings and granular building intell...

SageGlass

SageGlass®, a product of Saint-Gobain, is advanced dynamic glass that can be electronically tinted or cleared to optimize daylight and improve the human experience in buildings...

Linnea SA

Located in the Swiss canton of Ticino, Linnea is a high-quality manufacturer of active ingredients for use in the health food and cosmetic industries and pharmaceutical industries...

AsiaInspection

Founded in Hong Kong, AsiaInspection (www.asiainspection.com) is the leading online platform for performing product inspections, testing and factory audits in Asia for impor...

22nd Century Group, Inc.

Founded in 1998, 22nd Century Limited, LLC (22nd Century) is a plant biotechnology company whose proprietary technology allows for the level of nicotine (and other nicotinic alkal...

Clinical Trials [638 Associated Clinical Trials listed on BioPortfolio]

Pertussis Immunisation and Food Allergy

Aim To assess the possible food allergy-preventive benefit of using whole cell pertussis(wP) vaccination compared with acelluar pertussis vaccine(aP) for whooping cough vaccination in chil...

Effects of Physical Activity on Math - an RCT

Background Increased physical activity can improve cognition and academic skills. However due to economic concerns and increasing focus on standardized testing, PA in schools often receiv...

Impact of a Specific Training Program on the Neuromodulation of Pain in Fibromyalgia Subjects

Fibromyalgia affects 1.4 now 2.2% of the general population whose symptom is the presence of widespread pain in all four quadrants of the body. Currently, there is no causal treatment of f...

Hormonal Sensitivity in Patients With Noonan and LEOPARD Syndromes

Noonan and LEOPARD syndromes share, with variable severity, different clinical traits, notably craniofacial manifestations, cardiopathies, short stature, and juvenile cancers. The main ge...

Benefits of MPACT in Locally Advanced Head and Neck Cancer Patients Undergoing Chemoradiotherapy

The goal of this study is to test, in a randomized controlled trial among head and neck cancer patients, the short and longer term effects of the MPACT (Maintaining Physical Activity durin...

Effect of Fluticasone Furoate Inhalation Powder on the Hypothalamic-pituitary-adrenocortical Axis of Children Aged 5-11 Years With Asthma

Inhaled corticosteroids (ICS) have a number of known class effects including hypothalamic-pituitary-adrenocortical (HPA) axis suppression. Although the safety of inhaled Fluticasone Furoat...

The Dementia Symptom Management at Home Program

Persons with dementia and their caregivers are often cared for in the community through home healthcare (HHC). While these patients and their caregivers need significant help and often hav...

Hyperoxia, Erythropoiesis and Microcirculation in Critically Ill Patient

Prospective observational study in 40 adult critically ill patients. Patients were eligible if they were mechanically ventilated with an FiO2 ≤0.5 and PaO2/FiO2 ≥200 mmHg and hemodynam...

Long-term Immunogenicity of a HPV Vaccine in SLE

To study the 5-year immunogenicity against a quadrivalent HPV vaccine in patients with SLE and healthy controls.

Seton Hill University--Personal Empowerment Program

It is widely acknowledged that cardiovascular disease prevention requires intervention as early in the human lifespan as practical. A window of opportunity presents in early adulthood when...

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Medical and Biotech [MESH] Definitions

The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat.

A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

This area is bounded medially by the mammillothalamic tract and the anterior column of fornix. The medial edge of the internal capsule and the subthalamic region form its lateral boundary. It contains the lateral hypothalamic nucleus, tuberomammillary nucleus, lateral tuberal nuclei, and fibers of the MEDIAL FOREBRAIN BUNDLE. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p710)

The front portion of the HYPOTHALAMUS separated into the preoptic region and the supraoptic region. The preoptic region is made up of the periventricular gray matter of the rostral portion of the third ventricle and contains the preoptic ventricular nucleus and the medial preoptic nucleus. The supraoptic region contains the PARAVENTRICULAR HYPOTHALAMIC NUCLEUS, the SUPRAOPTIC NUCLEUS, the ANTERIOR HYPOTHALAMIC NUCLEUS, and the SUPRACHIASMATIC NUCLEUS.

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.


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