Hypothalamic Controls - Biotech, Pharma and Life Science Channel

01:58 EDT 30th September 2014 | BioPortfolio

PubMed Articles [4402 Associated PubMed Articles listed on BioPortfolio]

Impact of childhood obesity on cardiac structure and function.

Obesity prevalence is still on the rise worldwide in both adults and children. In adults, obesity is a significant cardiovascular risk factor associated with increased morbidity and mortality. In chil...

Development of 23 individual TaqMan(®) real-time PCR assays for identifying common foodborne pathogens using a single set of amplification conditions.

Most of the acute intestinal diseases are caused by foodborne pathogens with infants and elderly people being at major risk. The aim of this study was to develop a procedure to simultaneously detect 2...

Rapid Enzymatic Hydrolysis Using a Novel Recombinant β-Glucuronidase in Benzodiazepine Urinalysis.

Only trace amounts of parent benzodiazepines are present in urine following extensive metabolism and conjugation. Thus, hydrolysis of glucuronides is necessary for improved detection. Enzyme hydrolysi...

The influence of body position and microclimate on ketamine and metabolite distribution in decomposed skeletal remains.

The influence of body position and microclimate on ketamine (KET) and metabolite distribution in decomposed bone tissue was examined. Rats received 75 mg/kg (i.p.) KET (n = 30) or remained drug-free (...

The Chicago Classification of Motility Disorders: An Update.

The Chicago Classification defines esophageal motility disorders in high resolution manometry. This is based on individual scoring of 10 swallows performed in supine position. Disorders of esophago-ga...

Circulating microRNA 483-5p as a novel biomarker for diagnosis survival prediction in multiple myeloma.

Dysregulation of miRNA expression plays an important role in cancer development, and circulating miRNAs are biomarkers of several cancers. We explored whether the miRNAs in plasma could be useful clin...

Association between Toll-like receptor 4 and interleukin 17 gene polymorphisms and colorectal cancer susceptibility in Northeast China.

Limited studies about the effects of TLR 4 and IL17 polymorphisms (SNPs) on the risk of colorectal cancer (CRC) have yielded inconsistent results. Totally, 601 CRC patients and 627 controls were enrol...

Nucleus accumbens core neurons encode value-independent associations necessary for sensory preconditioning.

Reinforcement-based learning models predict that the strength of association between cues and outcomes is driven by aspects of outcome value. However, animals routinely make associations between conti...

A Prospective Randomized Controlled Trial of the Natural History of Idiopathic Scoliosis versus treatment with the Spinecor brace. Sosort Award 2011 Winner.

The purpose of this randomized controlled trial was to evaluate the efficacy of the Dynamic SpineCor brace for early idiopathic scoliosis (15°-30°) compared to the natural evolution of the disease. ...

Increased of exhaled breath condensate neutrophil chemotaxis in acute exacerbation of COPD.

BackgroundNeutrophils have been involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). Underlying mechanisms of neutrophil accumulation in the airways of stable and exacerbated ...

News Articles [554 Associated News Articles listed on BioPortfolio]

Reappraisal of known malaria resistance loci in a large multicenter study

The Malaria Genomic Epidemiology Network reports a large multicenter association study for severe malaria due to Plasmodium falciparum in 11,890 cases and 17,441 controls from 12 locations in Africa, ...

New insights into how the heart forms may help identify heart defects

Cdc42 controls embryonic heart formation

New molecule offers potential in targeted treatment of osteoporosis

New research from the US has demonstrated the potential of a new molecule to treat osteoporosis and other autoimmune diseases in a more targeted way than is currently possible.A team from the Washingt...

Supreme Court May Hand Back Billions of Dollars to Self-insured Plans On BCBS Appeals – ERISAclaim.com Demystifies

On Sep 15, 2014, in Supreme Court (SC), Blue Cross Blue Shield Association, et al. filed an Amici Curiae Brief in support of BCBSM, appealing a Sixth Circuit Court award of $6.1 million to a self-insu...

Zafgen completes patient enrolment of Phase IIa trial of obesity drug Beloranib

US-based biopharmaceutical firm Zafgen has completed patient enrolment in its Phase IIa clinical trial (ZAF-221) of Beloranib to treat hypothalamic injury-associated obesity (HIAO).

Weight cycling linked to relapse-prone bipolar course

Patients with bipolar disorder are more likely than healthy controls to have a history of weight cycling, which in turn is associated with an increased likelihood of manic and depressive episodes, res...

Epizyme, Inc. to Present at Upcoming Events in October

Epizyme, Inc. (NASDAQ: EPZM), a clinical stage biopharmaceutical company creating innovative personalized therapeutics for patients with genetically defined cancers, today ...

All New MV-1 Wheelchair Accessible Minivan

LOS ANGELES, Sept. 25, 2014 /PRNewswire/ -- Better Life Mobility Center is thrilled to offer its customers new and improved models of MV-1 mobility vans by Mobility Ventures LLC, an AM General Co...

Global covariation of carbon turnover times with climate in terrestrial ecosystems

The response of the terrestrial carbon cycle to climate change is among the largest uncertainties affecting future climate change projections. The feedback between the terrestrial carbon cycle and cli...

[Comment] Statins and type 2 diabetes: genetic studies on target

The topic of the side-effects of statin treatment is important and controversial. In The Lancet, Daniel Swerdlow and colleagues used an updated meta-analysis of trials to investigate whether or not st...

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Companies [33 Associated Companies listed on BioPortfolio]

Digital Lumens

Digital Lumens is a global supplier of enterprise-scale intelligent LED lighting to commercial and industrial customers, delivering 90% energy savings and granular building intell...

SageGlass

SageGlass®, a product of Saint-Gobain, is advanced dynamic glass that can be electronically tinted or cleared to optimize daylight and improve the human experience in buildings...

Linnea SA

Located in the Swiss canton of Ticino, Linnea is a high-quality manufacturer of active ingredients for use in the health food and cosmetic industries and pharmaceutical industries...

AsiaInspection

Founded in Hong Kong, AsiaInspection (www.asiainspection.com) is the leading online platform for performing product inspections, testing and factory audits in Asia for impor...

22nd Century Group, Inc.

Founded in 1998, 22nd Century Limited, LLC (22nd Century) is a plant biotechnology company whose proprietary technology allows for the level of nicotine (and other nicotinic alkal...

Daylight Solutions, Inc.

Daylight Solutions develops molecular detection, imaging and high-power illumination systems for use in industrial process controls, scientific research, medical diagnostics, envi...

China Kangtai Cactus Bio-tech Inc.

China Kangtai Cactus Bio-tech, Inc. is a leading grower, developer, producer, and marketer of cactus-derived products, including nutraceuticals, nutritious food, health and energy...

China Kangtai Cactus Bio-tech, Inc.

China Kangtai Cactus Bio-tech, Inc. is a leading grower, developer, producer, and marketer of cactus-derived products, including nutraceuticals, nutritious food, health and energy...

Vendormate, Inc.

Vendormate protects the health of supply chains with a unique vendor credentialing and compliance monitoring solution. The program assures compliance with both internal policies and government mandate...

China Kangtai Cactus Biotech Inc.

China Kangtai Cactus Biotech, Inc. is a leading grower, developer, producer, and marketer of cactus-derived products, including nutraceuticals, nutritious food, health and energy ...

Clinical Trials [556 Associated Clinical Trials listed on BioPortfolio]

Genotype-directed Neoadjuvant Chemoradiation for Rectal Carcinoma

Determine if genotype-directed neoadjuvant chemoradiation, using information from the thymidylate synthase promoter polymorphism, result in a greater degree of tumor downstaging in high ri...

Testing Tissue Sodium Stores in CAPD Patients—Aims 1 & 2

The investigators' overarching goal is to improve long-term outcomes for end stage renal disease (ESRD) patients. In this study we focus specifically on patients receiving peritoneal dialy...

Piecemeal Versus En Bloc Resection of Large Rectal Adenomas

Currently, colonoscopy is the safest way to detect bowel tumors and polyps, since these can be biopsied and removed in one working process. If the size of adenomas is larger than 2 cm, res...

Second Laparoscopic Surgery for Recurrent Unilateral Endometriomas.

This retrospective case-control study was performed in an Academic centre for the diagnosis and treatment of endometriosis. It included patients with recurrent unilateral endometriomas who...

The Effect of Short-term Atorvastatin Treatment on Immune Responses to Pneumovax 23

The purpose of this research study is to: Improve the effectiveness of vaccinations by identifying the effect of cholesterol medication, statins, on immune responses.

Safety of Driving After Minor Surgery With Monitored Anesthesia Care

Patients are currently advised to refrain from driving motor vehicles or using public transportation unescorted for a 24 hour period if they undergo any minor ambulatory surgical procedure...

Hip Pathomorphology in Collegiate Athletes and Controls

The primary objective of this study is to investigate factors hypothesized to influence the prevalence of hip pathomorphology (femoroacetabular impingement, dysplasia) in young adults. To ...

Therapy for Pediatric Hodgkin Lymphoma

With the success of current chemotherapy for Hodgkin's disease, the goal of this protocol is to maintain the currently successful cure rate and reduce treatment related side effects and lo...

Effect of AIDET on Physician-Patient Communication

Patient satisfaction is an important aspect of care and is gaining increasing importance as a measure of Healthcare quality. Tools for improving physician-patient communication are availab...

Host Immune Response to Clostridium Difficile Infection in Inflammatory Bowel Disease Patients

The inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn's disease (CD) are chronic conditions affecting approximately 1.4 million Americans. The burden of Clostridium dif...

Medical and Biotech [MESH] Definitions

The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat.

A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

This area is bounded medially by the mammillothalamic tract and the anterior column of fornix. The medial edge of the internal capsule and the subthalamic region form its lateral boundary. It contains the lateral hypothalamic nucleus, tuberomammillary nucleus, lateral tuberal nuclei, and fibers of the MEDIAL FOREBRAIN BUNDLE. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p710)

The front portion of the HYPOTHALAMUS separated into the preoptic region and the supraoptic region. The preoptic region is made up of the periventricular gray matter of the rostral portion of the third ventricle and contains the preoptic ventricular nucleus and the medial preoptic nucleus. The supraoptic region contains the PARAVENTRICULAR HYPOTHALAMIC NUCLEUS, the SUPRAOPTIC NUCLEUS, the ANTERIOR HYPOTHALAMIC NUCLEUS, and the SUPRACHIASMATIC NUCLEUS.

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

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