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Hypothalamic Controls - Biotech, Pharma and Life Science Channel

05:08 EDT 30th July 2014 | BioPortfolio

PubMed Articles [4412 Associated PubMed Articles listed on BioPortfolio]

Development of 23 individual TaqMan(®) real-time PCR assays for identifying common foodborne pathogens using a single set of amplification conditions.

Most of the acute intestinal diseases are caused by foodborne pathogens with infants and elderly people being at major risk. The aim of this study was to develop a procedure to simultaneously detect 2...

Characterization and cytocompatibility of an antibiotic/chitosan/cyclodextrins nanocoating on titanium implants.

A novel ciprofloxacin loaded chitosan nanoparticle-based coating onto titanium substrates has been developed and characterized to obtain an orthopaedic implant surface able to in situ release the anti...

Preparation and characterization of double crosslinked hydrogel films from carboxymethylchitosan and carboxymethylcellulose.

A novel crosslinked hydrogel film was prepared from carboxymethylchitosan (CMCS) and carboxymethylcellulose (CMC) by ionical and covalent crosslinking with CaSO4 and genipin, respectively. The swellin...

Characterization of cassava starch based foam blended with plant proteins, kraft fiber, and palm oil.

Cassava starch foam (CSF) trays blended with zein, gluten, soy protein, kraft fiber, and palm oil at various concentrations: 0, 5, 10 and 15% by weight of starch, were characterized. The addition of z...

Controlling cell behavior with peptide nano-patterns.

Proper cell polarization and division are critical for a developing organism and a number of downstream biological processes including cancer metastasis, cell migration, and organelle organization. Bo...

Development of a rapid detection system for opportunistic pathogenic Cronobacter spp. in powdered milk products.

Certain species of the genus Cronobacter are considered opportunistic pathogens, but their detection in milk products according to ISO/TS 22964 may take up to six days. The aim of this study was to de...

Serotonin transporter gene alters insula activity to threat in social anxiety disorder.

Amygdala and insula hyper-reactivity to threat is implicated in social anxiety disorder (SAD) yet inconsistencies in activation have been reported. One source of variance are individual differences in...

Internal Contamination of an Irradiator Discovered During Security Enhancement.

High-risk radioactive sources regulated under Increased Controls Regulations have been protected by licensed facilities, but the federal government has placed significant emphasis on these sources and...

Association between infection of hepatitis B virus and onset risk of B-cell non-Hodgkin's lymphoma: a systematic review and a meta-analysis.

Whether an association between hepatitis B virus (HBV) infection and B-cell non-Hodgkin's lymphoma (B-NHL) risk exists is an open question. In order to provide quantification of the issue, we carried...

Elevated pretreatment serum concentration of YKL-40: An independent prognostic biomarker for poor survival in patients with colorectal cancer.

Serum YKL-40 levels have been associated with a poor prognosis in patients with several cancer types. However, the role of YKL-40 and its relationship with colorectal cancer are poorly understood. Pre...

News Articles [557 Associated News Articles listed on BioPortfolio]

Indian Industry Sues Pricing Watchdog, Fearing Investment Fallout

The Indian drug industry has appealed to courts against the latest decision of the country’s pricing watchdog to include scores of drugs under price controls, setting in motion what could be a bitte...

Gentronix achieves prospective membership of the UK GLP compliance monitoring programme

This means that, from 22nd July 2014, GLP compliance can be claimed for work conducted by Gentronix. The company is currently able to offer the GLP assays defined in the OECD Guidelines for the Testi...

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

Andrew Singleton and colleagues report a large-scale meta-analysis of genome-wide association data in Parkinson's disease using over 13,000 cases and 95,000 controls plus additional samples for replic...

An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action

Host defense to bacterial infection and pulmonary inflammation is regulated by a circadian clock within lung epithelial cells and glucocorticoids.

Protein that controls genes plays key role in brain to treat obesity and diabetes

A protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism, UT Southwestern Medical Center researchers have found.

ZeptoMetrix releases NATtrol RP Multimarker Controls - MDZ001

ZeptoMetrix Corporation, an industry leader and innovator of quality, reliable and trusted products and services for infectious disease diagnostic development, is pleased to announce the release of NA...

PhRMA comments on Medicare Rights Center paper

“Finding viable solutions to contain Medicare costs is critically important, but imposing price controls in Medicare would hurt the millions of seniors who rely on the Part D program to access the m...

Manipulating key protein in brain holds potential against obesity, diabetes

A protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism, researchers have found. The research potentially could lead to new the...

ZeptoMetrix™ Corporation (ZMC) Releases FDA Class 1 Exempt, IVD and CE Labeled NATtrol™ RP Multimarker Controls

ZeptoMetrix™ Corporation (ZMC), launches a new FDA Class 1 exempt, in vitro diagnostic, CE marked, unassayed external run control intended for use with multiplexed, respiratory molecular assays. The...

High Vacuum Benchtop Solvent Evaporator

The EZ-2 Elite Centrifugal Evaporator from Genevac has been designed to provide unmatched final drying of stubborn samples and fast lyophilisation of HPLC fractions Benefiting from a high performance...

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Companies [32 Associated Companies listed on BioPortfolio]

Global Partners LP

A publicly traded master limited partnership, Global Partners LP is a midstream logistics and marketing company. Global owns, controls or has access to one of the largest terminal...

SAGE Electrochromics, Inc.

SAGE Electrochromics is the world’s leading manufacturer of advanced dynamic glass that can be tinted or cleared to optimize daylight and improve the human experience in buil...

China Kangtai Cactus Bio-tech, Inc.

China Kangtai Cactus Bio-tech, Inc. is a leading grower, developer, producer, and marketer of cactus-derived products, including nutraceuticals, nutritious food, health and energy...

China Kangtai Cactus Biotech Inc.

China Kangtai Cactus Biotech, Inc. is a leading grower, developer, producer, and marketer of cactus-derived products, including nutraceuticals, nutritious food, health and energy...

Reata Pharmaceuticals, Inc.

Reata Pharmaceuticals is the leader in discovering and developing novel, oral anti-inflammatory drugs that activate Nrf2, the primary regulator of cellular antioxidant and detoxif...

SageGlass

SageGlass®, a product of Saint-Gobain, is advanced dynamic glass that can be electronically tinted or cleared to optimize daylight and improve the human experience in buildings...

Convergent Dental Inc.

Convergent Dental, Inc., is a privately managed dental equipment and technology company and is the developer of Solea™, the world’s first computer-aided, CO2 laser syste...

Tripwire

Tripwire is a leading global provider of risk-based security and compliance management solutions, enabling enterprises, government agencies and service providers to effectively co...

Linnea SA

Located in the Swiss canton of Ticino, Linnea is a high-quality manufacturer of active ingredients for use in the health food and cosmetic industries and pharmaceutical industries...

Infogix Inc.

Many of the world’s largest enterprises depend on Infogix to transform their operations. Through the use of Infogix solutions, customers are able to control, analyze and impr...

Clinical Trials [551 Associated Clinical Trials listed on BioPortfolio]

Down Syndrome Metabolic Health Study

The purpose of this research study is to determine which measures best capture cardiovascular disease (CVD) risk and type 2 diabetes (T2DM) risk in children and adolescents with Down syndr...

Hip Pathomorphology in Collegiate Athletes and Controls

The primary objective of this study is to investigate factors hypothesized to influence the prevalence of hip pathomorphology (femoroacetabular impingement, dysplasia) in young adults. To...

Osteoporosis Research Registry

The aim of this research registry is to collect information on individuals with osteoporosis, those with risk factors for osteoporosis, and comparative healthy controls. Bone mineral densi...

Cognitive Correlates of Substance Abuse - 11

The purpose of this study is to characterize the cognitive performance of methamphetamine abusers by comparing them with cocaine abusers and normal controls.

A Phase I Pharmacokinetic and Tolerance Study of 28-Day Regimens of Oral Ganciclovir

To determine the pharmacokinetics (blood levels) of three dose treatment plans of oral ganciclovir during a 28-day dosing period. Other purposes of the study are to determine in a populati...

Study of Abnormal Blood Clotting in Children With Stroke

Effective treatment and prevention strategies for childhood stroke and porencephaly can only be developed once the causes are understood. There is increasing evidence that inherited and a...

Phase II Study of Stereotypes and Mental Retardation: Neurobiological Basis

OBJECTIVES: I. Determine differences between persons with repetitive behavior disorders and matched controls on measures of motor control relevant to basal ganglia pathophysiology. II....

Models of Disordered Knowledge and Memory Systems in Dementia and Related Disorders

Patients with Alzheimer's disease (AD) perform poorly on tasks dependent on access to, and utilization of, previously acquired knowledge and skills. It has been commonly assumed that impa...

Study of Ibuprofen to Preserve Lung Function in Patients With Cystic Fibrosis

OBJECTIVES: I. Determine the effect of different doses of ibuprofen on neutrophil (polymorphonuclear leukocyte; PMN) delivery to a mucosal surface (the oral mucosa) in patients with cyst...

Phase II Randomized Study of Early Surgery Vs Multiple Sequential Antiepileptic Drug Therapy for Infantile Spasms Refractory to Standard Treatment

OBJECTIVES: I. Evaluate the efficacy of surgical resection of an identifiable zone of cortical abnormality versus multiple drug therapy in children with infantile spasms refractory to sta...

Medical and Biotech [MESH] Definitions

The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat.

A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

This area is bounded medially by the mammillothalamic tract and the anterior column of fornix. The medial edge of the internal capsule and the subthalamic region form its lateral boundary. It contains the lateral hypothalamic nucleus, tuberomammillary nucleus, lateral tuberal nuclei, and fibers of the MEDIAL FOREBRAIN BUNDLE. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p710)

The front portion of the HYPOTHALAMUS separated into the preoptic region and the supraoptic region. The preoptic region is made up of the periventricular gray matter of the rostral portion of the third ventricle and contains the preoptic ventricular nucleus and the medial preoptic nucleus. The supraoptic region contains the PARAVENTRICULAR HYPOTHALAMIC NUCLEUS, the SUPRAOPTIC NUCLEUS, the ANTERIOR HYPOTHALAMIC NUCLEUS, and the SUPRACHIASMATIC NUCLEUS.

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

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