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Hypothalamic Controls - Biotech, Pharma and Life Science Channel

22:38 EDT 22nd August 2017 | BioPortfolio

PubMed Articles [4322 Associated PubMed Articles listed on BioPortfolio]

Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors.

Cannabinoid (CB) and opioid systems are both involved in analgesia, food intake, mood and behavior. Due to the co-localization of µ-opioid (MOR) and CB1 receptors in various regions of the central ne...

The seroprevalence of antithyroid peroxidase antibodies in bipolar families and bipolar twins: results from two longitudinal studies.

Previous studies of our group among bipolar offspring and bipolar twins showed significant higher prevalence's and levels of antithyroid peroxidase antibodies (TPO-Abs) in offspring and co-twins (with...

(123)IFP-CIT ENC-DAT normal database: the impact of the reconstruction and quantification methods.

[(123)I]FP-CIT is a well-established radiotracer for the diagnosis of dopaminergic degenerative disorders. The European Normal Control Database of DaTSCAN (ENC-DAT) of healthy controls has provided ag...

Effect of a 12-week integrative oncology intervention on gastro-intestinal concerns in patients with gynecological and breast cancer undergoing chemotherapy.

Research on the long-term effects of complementary and integrative medicine (CIM) is limited. In this study, we explore the impact of a CIM intervention on gastro-intestinal (GI)-related concerns in p...

Association between MDM2-SNP309 and p53R72P polymorphisms and the risk of bladder cancer in the Mongolian population.

The current study aims to investigate whether MDM2-SNP309 and p53R72P polymorphisms were associated with the risk of bladder cancer in Mongolian populations. These polymorphisms were evaluated in 79 c...

Single-cell mechanogenetics using monovalent magnetoplasmonic nanoparticles.

Spatiotemporal interrogation of signal transduction at the single-cell level is necessary to answer a host of important biological questions. This protocol describes a nanotechnology-based single-cell...

Effectiveness of a 16-Week High-Intensity Cardioresistance Training Program in Adults.

Greenlee, TA, Greene, DR, Ward, NJ, Reeser, GE, Allen, CM, Baumgartner, NW, Cohen, NJ, Kramer, AF, Hillman, CH, and Barbey, AK. Effectiveness of a 16-week high-intensity cardioresistance training prog...

Influence of Temperature on the Efficacy of Homologous and Heterologous DNA Vaccines against Viral Hemorrhagic Septicemia in Pacific Herring.

Homologous and heterologous (genogroup Ia) DNA vaccines against viral hemorrhagic septicemia virus (genogroup IVa) conferred partial protection in Pacific Herring Clupea pallasii. Early protection at ...

Angiogenesis and oxidative stress-related gene variants in recurrent pregnancy loss.

Recurrent pregnancy loss (RPL) affects ~3-5% of couples attempting to conceive and in around 50% of cases the aetiology remains unknown. Adequate vascularisation and placental circulation are indispen...

Defibrotide for children and adults with hepatic veno-occlusive disease post hematopoietic cell transplantation.

Hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is a complication that is typically associated with conditioning for hematopoietic stem cell transplantation (HSCT). In patient...

News Articles [655 Associated News Articles listed on BioPortfolio]

Motorola rdx series radios pdf

central will ship next business day! 1 is an 8, receive a FREE radio plus motorola rdx series radios pdf prepaid card for every six Motorola RD Series radios purchased! 30mm  scope to a Picatinny rai...

GW Pharmaceuticals (GWPH) - Rolling submission initiated

Edison Investment Research - Pharmaceutical & healthcare - GW Pharmaceuticals: GW Pharmaceuticals recently announced that a rolling NDA filing for Epidiolex in both Dravet syndrome and Lennox-Gastaut ...

Clinical Study Shows That Retinal Imaging May Detect Signs of Alzheimer’s Disease

Researchers at Cedars-Sinai and NeuroVision LLC Publish Proof of Concept Study on Experimental Optical Imaging System, Demonstrating Detection of Retinal Beta-Amyloid, a Hallmark ...

UK Condemned over 'Shocking' Export of Deadly Weedkiller to Poorer Countries

Paraquat is a highly toxic weedkiller that is so lethal, a single sip can be fatal. It can also be absorbed through the skin and has been linked to Parkinson’s disease. Paraquat has been outlawed in...

Bio-Techne To Present At The Baird 2017 Global Healthcare Conference

MINNEAPOLIS, Aug. 22, 2017 /PRNewswire/ -- Bio-Techne Corporation (NASDAQ:TECH) today announced that Chuck Kummeth, President and Chief Executive Officer, and Jim Hippel, Chief Financial Officer ...

Female is not 'default sex' of embryos

A protein that controls removal of male reproductive tissue in female mice embryos has been discovered... 

Study: Patients with ankylosing spondylitis at greater odds for complications after THA

Compared with controls, patients with ankylosing spondylitis had greater odds for complications after total hip arthroplasty, according to results of a recently published study.“Although [total hip ...

P-syn in Nerve Fibers on Skin Biopsy May Help Diagnose Dementia with Lewy Bodies

This study compared 18 subjects diagnosed with dementia with Lewy bodies (DLB), 23 with nonsynucleinopathy dementia, and 25 healthy controls and demonstrated that phosphorylated alpha-synuclein was fo...

Novel fibrosis therapeutics: walking down the TGF-beta pathway

Recent weeks brought startling news of clinical trial successes in the treatment of Idiopathic Pulmonary Fibrosis (IPF). The clinical and commercial consequences have been heavily reviewed elsewhere (...

Therapeutic Drug Monitoring TDM Market 2021: US, Europe, JapanSupplier Shares and Strategies, Volume and Sales Segment Forecasts [Report Updated: 12072017] Prices from USD $8500

Complete report $8,500. nbsp;DataPack test volumes, sales forecasts, supplier shares $5,500.This new 313page report from VPGMarketResearch contains 83 tables and provides analysis of the global therap...

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Companies [44 Associated Companies listed on BioPortfolio]

BioProcess Technology Consultants Inc.

Founded in 1994, BPTC is the recognized worldwide leader in biologics Chemistry, Manufacturing, and Controls consulting, providing a full range of technical, regulatory, and strat...

Kyriba Corp.

Kyriba is the global leader in cloud treasury solutions, delivering Software-as-a-Service (SaaS) treasury technology to corporate CFOs and Treasurers. More than 1,300 global organ...

Alfresco Software

Alfresco provides modern enterprise content management (ECM) software built on open standards that enables organizations to unlock the power of their business-critical content. Wi...

Excel Dryer, Inc.

For over 50 years, Excel Dryer has been manufacturing the finest American made hand dryers featuring the XLERATOR® Hand Dryer. Excel Dryer is a family owned and operated compan...

Voxello, Inc.

Voxello provides solutions for disabled hospitalized patients who cannot communicate by traditional means. The company’s first product, the noddle™, allows disabled pati...

Degree Controls, Inc.

Indigo-Clean

Indigo-Clean is an affiliate of Kenall Manufacturing, which has earned a reputation for superior quality, innovation, sustainability and exceptional value in the lighting industry...

Intermatic Incorporated

Intermatic has delivered quality products and service to its customers for over 100 years. As a leading manufacturer of controls and energy-management solutions for electrical, HV...

Xamin, Inc.

Founded in 1999, Xamin, Inc. is a Chicago based company offering industry leading IT services to financial institutions as well as other highly regulated industries. The company p...

NanoSpeed Diagnostics, Inc.

DiaSys Diagnostic Systems is a leading specialist in the development and manufacturing of diagnostic system solutions of highest quality, trusted by customers in more than 100 cou...

Clinical Trials [1099 Associated Clinical Trials listed on BioPortfolio]

Serum Ferritin as a Non-invasive Marker in Prediction of Hepatic Fibrosis Among NAFLD Patients

This study was designed to assess the relation between serum ferritin and hepatic fibrosis in patients with NAFLD. It included 83 patients with NAFLD with or without hepatic fibrosis, in a...

Study of Sensorimotor Compatibility Effects in Bipolar Affective Disorder.

Based in an embodied approach of cognition, several studies have highlighted a direct link between perception of an object or an emotion and the associated motor responses. This study inve...

fMRI of Hypothalamic Responses to Glucose, Fructose, Sucrose and Sucralose

The study will consist of five occasions with one week in between. BOLD signal intensity of the hypothalamus will be measured using fMRI. Measurements will be done before and after drinkin...

Gilenya's Impact on Cognitive Function and Thalamic Volumes

This evaluation will be a one-year feasibility study to characterize the neuroprotective benefits of Gilenya and its effects on cognition and grey matter volumes. The study will enroll 15 ...

Nonsurgical Periodontal Treatment in Patients With Social Phobia

Objective: To investigate the impact of nonsurgical periodontal treatment in patients with social anxiety disorder (SAD) and controls without phobia.

Prevalence of Serum-Vitamin D Abnormalities, Periodontitis and Anaemia in Patients With Melasma

Melasma is a commonly acquired, pigmentary disorder characterized by symmetric melanosis of the face. The relation between vitamin D deficiency and periodontitis have been evaluated and re...

High-Intensity Aerobic Lifelong Training--AF

This study is a single-center RCT. Potential subjects with symptomatic non-permanent AF will be enrolled to determine the effect of sprint interval training (SIT) in comparison to moderate...

Botulinum Toxin for Cramps in Diabetic Neuropathy

Objective: previous studies suggest that botulinum toxin A (BoNT/A) can reduce muscle hyperactivity. Research Design and Methods: a single-center, double-blind and placebo-controlled stud...

The Role of the Thymus in Type I Diabetes.

Regulatory T lymphocytes play a major role in the protection from autoimmune pathology. Defects in immunosuppression mediated by these cells is therefore suspected to contribute to these d...

Transcendental Meditation and Reduced Trauma Symptoms in Women Inmates

This pilot study investigated the trauma reducing effects of the Transcendental Meditation program on female prisoners The study was conducted over the 4 month period and measured total tr...

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Medical and Biotech [MESH] Definitions

The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat.

A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

This area is bounded medially by the mammillothalamic tract and the anterior column of fornix. The medial edge of the internal capsule and the subthalamic region form its lateral boundary. It contains the lateral hypothalamic nucleus, tuberomammillary nucleus, lateral tuberal nuclei, and fibers of the MEDIAL FOREBRAIN BUNDLE. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p710)

The front portion of the HYPOTHALAMUS separated into the preoptic region and the supraoptic region. The preoptic region is made up of the periventricular gray matter of the rostral portion of the third ventricle and contains the preoptic ventricular nucleus and the medial preoptic nucleus. The supraoptic region contains the PARAVENTRICULAR HYPOTHALAMIC NUCLEUS, the SUPRAOPTIC NUCLEUS, the ANTERIOR HYPOTHALAMIC NUCLEUS, and the SUPRACHIASMATIC NUCLEUS.

Cell surface receptors that bind the hypothalamic hormones regulating pituitary cell differentiation, proliferation, and hormone synthesis and release, including the pituitary-releasing and release-inhibiting hormones. The pituitary hormone-regulating hormones are also released by cells other than hypothalamic neurons, and their receptors also occur on non-pituitary cells, especially brain neurons, where their role is less well understood. Receptors for dopamine, which is a prolactin release-inhibiting hormone as well as a common neurotransmitter, are not included here.

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