Hypothalamic Controls - Biotech, Pharma and Life Science Channel

12:13 EDT 1st August 2015 | BioPortfolio

PubMed Articles [4304 Associated PubMed Articles listed on BioPortfolio]

Immune Tolerance Induction against Experimental Autoimmune Encephalomyelitis (EAE) Using A New PLP-B7AP Conjugate that Simultaneously Targets B7/CD28 Costimulatory Signal and TCR/MHC-II Signal.

Most of the current therapies used in the treatment of multiple sclerosis (MS) are either ineffective or have adverse side effects. As such, there is a need to develop better therapies that specifical...

Electrically stimulated osteogenesis on Ti-PPy/PLGA constructs prepared by laser-assisted processes.

This work describes a versatile laser-based protocol for fabricating micro-patterned, electrically conductive titanium-polypyrrole/poly(lactic-co-glycolic)acid (Ti-PPy/PLGA) constructs for electricall...

Involvement of pro-inflammatory cytokines and growth factors in the pathogenesis of Dupuytren's contracture: a novel target for a possible future therapeutic strategy?

Dupuytren's contracture (DC) is a benign fibro-proliferative disease of the hand causing fibrotic nodules and fascial cords which determine debilitating contracture and deformities of fingers and hand...

Circulating microRNAs as biomarkers of adult Crohn's disease.

Previous studies have found a differential expression of microRNAs (miRNAs) in the blood of patients with Crohn's disease (CD) compared with healthy controls. The aim of this study was to identify cir...

Incorporation of antimicrobial peptides on functionalized cotton gauzes for medical applications.

A large group of low molecular weight natural compounds that exhibit antimicrobial activity has been isolated from animals and plants during the past two decades. Among them, peptides are the most wid...

Emotional effect on cognitive control in implicit memory tasks in patients with schizophrenia.

The aim of this study was to reveal a potential effect of emotion on cognitive control in the implicit memory task with emotionally neutral and unpleasant words in healthy controls and patients with s...

Increased serum levels of brain-derived neurotrophic factor in autism spectrum disorder.

The aim of this study was to investigate the potential role of brain-derived neurotrophic factor (BDNF) in children with autism spectrum disorders (ASD) by measuring serum circulating levels of BDNF a...

Hippocampectomy disrupts trace eye-blink conditioning in rabbits.

The role of the hippocampus (HFC) in trace eye-blink conditioning was evaluated using a 100-ms tone conditioned stimulus (CS), a 300- or 500-ms trace interval, and a 150-ms air puff unconditioned stim...

Effect of a carbonated HAP/β-glucan composite bone substitute on healing of drilled bone voids in the proximal tibial metaphysis of rabbits.

A novel elastic hydroxyapatite-based composite of high surgical handiness has been developed. Its potential application in orthopedics as a filler of bone defects has been studied. The biomaterial was...

Impact of immunosuppressive therapy on hepatitis B vaccination in inflammatory bowel diseases.

The vaccination rate against hepatitis B virus (HBV) is low in inflammatory bowel disease (IBD) patients. The Consensus from the European Crohn's and Colitis Organisation on opportunistic infections r...

News Articles [488 Associated News Articles listed on BioPortfolio]

Researchers find tumor suppressor p53 controls signaling-mediated phagocytosis of apoptotic cells through DD1α

A team of researchers with affiliations to a number of research centers in the U.S. has found that the protein p53 serves as a controlling mechanism for apoptotic (naturally dying) cells through the i...

Gentronix achieves prospective membership of the UK GLP compliance monitoring programme

This means that, from 22nd July 2014, GLP compliance can be claimed for work conducted by Gentronix. The company is currently able to offer the GLP assays defined in the OECD Guidelines for the Testi...

Procura Announces SSAE 16 Certification

Procura, leading provider of post-acute software, is proud to announce that the company is now SSAE 16 SOC 1 certified. Boca Raton, FL (PRWEB) July 30, 2015 Procura, leading provider of post-acute so...

Epizyme to Report Second Quarter 2015 Financial Results and Provide Corporate Update on August 6, 2015

Epizyme, Inc. (NASDAQ: EPZM), a clinical stage biopharmaceutical company creating novel epigenetic therapeutics for cancer patients, announced today it will host a conference call...

The Pharmacy as Manufacturer: Automation Provides Quality Controls to Ensure Repeatability in IV Compounding

Thomas Doherty | aRxium Quality control is fundamental to manufacturing. Ensuring the consistency of inputs (supply chain, inventory and components), processes and the production environment is e...

Cleave Biosciences Granted Key U.S. Patent Covering CB-5083

BURLINGAME, Calif., July 30, 2015 /PRNewswire/ -- Cleave Biosciences today announced that the United States Patent and Trademark Office has granted the company a key patent providing the protecti...

Energy Management Revenue for Healthcare Markets is Expected to Reach $2.2 Billion by 2024, According to Navigant Research

An increasing demand for resiliency is expected to drive the market for energy management in hospitals, report finds A recent report from Navigant Research examines the...

Clare Controls Signs ImageCrafters as Manufacturer's Rep

SARASOTA, FLA., July 29, 2015 (GLOBE NEWSWIRE) -- Clare Controls, a provider of simple-to-install, -maintain, and -use home automation solutions that give homeowners far-reaching control over their o...

McPherson VUVAS UV spectrophotometers

McPherson offers deep and vacuum ultraviolet (VUV) wavelength spectral test systems. The instruments are suitable for analysing doped crystalline materials, deep UV optics and coatings. They directly ...

Quality Control of Immunoassay Testing is Now Stable for 5 Years

Thermo Scientific MAS Liquimmune controls offer extended shelf life for fewer costly lot changes Clinical chemistry and manufacturing laboratories performing quality co...

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Companies [39 Associated Companies listed on BioPortfolio]

Degree Controls, Inc.

Indigo-Clean

Indigo-Clean is an affiliate of Kenall Manufacturing, which has earned a reputation for superior quality, innovation, sustainability and exceptional value in the lighting industry...

Intermatic Incorporated

Intermatic has delivered quality products and service to its customers for over 100 years. As a leading manufacturer of controls and energy-management solutions for electrical, HV...

Xamin, Inc.

Founded in 1999, Xamin, Inc. is a Chicago based company offering industry leading IT services to financial institutions as well as other highly regulated industries. The company p...

NanoSpeed Diagnostics, Inc.

DiaSys Diagnostic Systems is a leading specialist in the development and manufacturing of diagnostic system solutions of highest quality, trusted by customers in more than 100 cou...

Phytecs

Phytecs develops healthcare and nutrition products targeting the endocannabinoid system responsible for the regulation of nearly every physiologic process within the human ...

Digital Lumens

Digital Lumens is a global supplier of enterprise-scale intelligent LED lighting to commercial and industrial customers, delivering 90% energy savings and granular building intell...

SageGlass

SageGlass®, a product of Saint-Gobain, is advanced dynamic glass that can be electronically tinted or cleared to optimize daylight and improve the human experience in buildings...

Linnea SA

Located in the Swiss canton of Ticino, Linnea is a high-quality manufacturer of active ingredients for use in the health food and cosmetic industries and pharmaceutical industries...

AsiaInspection

Founded in Hong Kong, AsiaInspection (www.asiainspection.com) is the leading online platform for performing product inspections, testing and factory audits in Asia for impor...

Clinical Trials [652 Associated Clinical Trials listed on BioPortfolio]

Combination Chemoembolization and Stereotactic Body Radiation Therapy in Unresectable Hepatocellular Carcinoma

The purpose of this study is to develop better ways to treat liver cancer, known as hepatocellular carcinoma or HCC, while it is still in the liver. Many treatments exist to treat tumors i...

Addressing Racial/Ethnic Tobacco Health Disparities Via Group Intervention

The importance of reducing tobacco-associated health disparities between cannot be understated. Racial/ethnic minorities are less likely to quit, and tend to have elevated stress and depre...

Stress and Emotional Memory

A broad group of disorders is associated with severe stress existence in children or adolescents. The most characteristic result, and one of the most serious being the state of post-trauma...

NAFLD in Adolescents and Young Adults With PCOS

This project, "Nonalcoholic fatty liver disease (NAFLD), insulin resistance and dyslipidemia in adolescents and young adults with polycystic ovary syndrome (PCOS)" focuses on an at-risk ad...

The Effect of tDCS on a Motor-cognitive Dual-task Performance of Parkinson's Patients

The concurrent performance of two tasks, i.e., dual tasking (DT), is a common and ubiquitous every day phenomena. For example, people frequently walk while talking on a cellphone or drive ...

DC-CIK In Combination With Chemotherapy ( Gio / Oxaliplatin or Cisplatin ) Versus First-line Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric Adenocarcinoma Randomized Controlled Phase II Clinical Study of Treatment

This study evaluates the therapeutic effects of autologous dendritic cells co-cultured with cytokine-induced killer cells (DC-CIK) combined with S-1 ((Tegafur, Gimeracil, and Oteracil Pota...

MRI in Patients With Kennedy Disease

Kennedy disease is an inherited neuromuscular disorder that is characterized by progressive muscle wasting and weakness. It typically starts with muscle spasms and tremors in the arms, fol...

Inhalation/Nasal Corticosteroids and Prevalence of Hypothalamic-pituitary-adrenal (HPA) Axis Suppression in Human Immunodeficiency Virus (HIV)-Patients

Rationale: Case reports describe suppression of the hypothalamic-pituitary-adrenal (HPA) axis caused by local corticosteroids, most often with inhalation corticosteroids. The exact prevale...

Effect of Thyroid Hormone Replacement on Fatigability in Untreated Older Adults With Subclinical Hypothyroidism

Thyroid hormone is a key regulatory hormone for a range of physiological systems. An impaired function of the thyroid gland such as subclinical hypothyroidism (SCH) can affect quality of l...

Real-time Functional MRI and Neurofeedback of Brain Networks Mediating Trauma Memory Recall in PTSD

The purpose of the current study is to develop a better understanding of the brain mechanisms involved in psychological treatments for posttraumatic stress disorder (PTSD). This project wi...

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Medical and Biotech [MESH] Definitions

The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat.

A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

This area is bounded medially by the mammillothalamic tract and the anterior column of fornix. The medial edge of the internal capsule and the subthalamic region form its lateral boundary. It contains the lateral hypothalamic nucleus, tuberomammillary nucleus, lateral tuberal nuclei, and fibers of the MEDIAL FOREBRAIN BUNDLE. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p710)

The front portion of the HYPOTHALAMUS separated into the preoptic region and the supraoptic region. The preoptic region is made up of the periventricular gray matter of the rostral portion of the third ventricle and contains the preoptic ventricular nucleus and the medial preoptic nucleus. The supraoptic region contains the PARAVENTRICULAR HYPOTHALAMIC NUCLEUS, the SUPRAOPTIC NUCLEUS, the ANTERIOR HYPOTHALAMIC NUCLEUS, and the SUPRACHIASMATIC NUCLEUS.

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.


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