Hypothalamic Controls - Biotech, Pharma and Life Science Channel

12:40 EST 31st January 2015 | BioPortfolio

PubMed Articles [4441 Associated PubMed Articles listed on BioPortfolio]

Lack of Correlation Between the CCR5-Δ32 Mutation and Acute Myeloid Leukemia in Iranian Patients.

Chemokines and their receptors are crucially important in the pathogenesis of acute myeloblastic leukemia (AML). The CC chemokine receptor 5 (CCR5) is a specific chemokine receptor for CC chemokine li...

In Vitro Susceptibility of Wistar Rat Platelets to Hydrogen Peroxide and AAPH-Induced Oxidative Stress.

Hydroxyl and peroxyl radicals are biologically active species because of their likelihood to damage cellular constituents. An in vitro study on Wistar rats was conducted to investigate the influence o...

Circulating serum levels of IL-20 in multiple myeloma patients: its significance in angiogenesis and disease activity.

Angiogenesis is an important hallmark in multiple myeloma (MM) pathogenesis, with the participation of various versatile molecules. Interleukin-20 (IL-20) is a pro-inflammatory cytokine with diverse a...

Use of Penicillin and Streptomycin to Reduce Spread of Bacterial Coldwater Disease II: Efficacy of Using Antibiotics in Diluents and During Water Hardening.

Abstract Bacterial coldwater disease, caused by Flavobacterium psychrophilum, has lead to the loss of significant numbers of hatchery-reared salmonids. The bacteria can be spread from parent to progen...

Abnormal expression of PEX10 gene may be related to epilepsy associated with 1p36 copy number variations.

OBJECTIVE To assess the association of PEX10 gene and 1p36 copy number variations in 1p36 region with concurrent epilepsy through analyzing 3 cases. METHODS The karyotypes of 3 patients were determine...

Analysis of AGG interspersion of the FMR1 gene in fragile X syndrome.

OBJECTIVE To analyze (CGG)n repeats sequence and AGG interspersion correlated with unstable expansion of FMR1 gene in a general Chinese population. METHODS AmplideX FMR1 PCR Kit was used to amplify 38...

Clinical features of familial idiopathic basal ganglia calcification caused by a novel mutation in the SLC20A2 gene.

OBJECTIVE To describe clinical and genetic feature in a Chinese family with familial idiopathic basal ganglia calcification 3 (IBGC-3) caused by a novel mutation in the SLC20A2 gene. Methods Clinical ...

Association of cystathionine β-synthase gene polymorphisms with essential hypertension in ethnic Uyghurs and Hans from Xinjiang.

OBJECTIVE To investigate the cystathione beta synthase (CBS) gene T833C, G919A, 844ins68 polymorphisms and plasma homocysteine (Hcy) levels in ethnic Uyghur and Han patients with essential hypertensio...

Association between LOXL1 gene polymorphisms and primary open angle glaucoma in Sichuan population.

OBJECTIVE To investigate association between the lysyl oxidase-like 1 (LOXL1) gene single nucleotide polymorphism (SNP) and primary open-angle glaucoma (POAG) in Sichuan population.METHODS In this stu...

Correlation of insulin-like growth factor 1 expression in placenta with DNA methylation and fetal macrosomia.

OBJECTIVE To explore the correlation between methylation of insulin-like growth factor 1 (IGF-1) gene promoter and its placenta-specific expression and fetal macrosoma. METHODS One hundred twenty nine...

News Articles [508 Associated News Articles listed on BioPortfolio]

Myosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature

Elliott et al. use high-resolution imaging, microfabrication and computational analyses to show that the interplay between cell-surface curvature and activity and cortical recruitment of myosin II, ...

Pot is bad for young people, but so is punishing them

John Hopton for redOrbit.com - Your Universe Online Just about any Facebook feed will contain haphazard advice and opinion on the issue of marijuana, but what does sophisticated research have to say ...

Researchers find protein necessary for fertility performs different roles in sperm, eggs

The protein necessary for fertility in both sexes performs distinctly different roles in male and female gametes, according to a groundbreaking study, which included researchers from the University of...

TechNavio Says Heightened Demand for MEMS Pressure Sensors Will Transform the Global MEMS Market by 2019

TechNavio, a tech-focused research firm, has published a new report on the Global MEMS Market, which is expected to grow at a CAGR of 12.3 percent from 2014-2019. ...

Convergent Dental Celebrates Explosive Growth, Widespread Adoption of its Innovative Solea CO2 Hard and Soft Tissue Dental Laser

Yankee Dental Congress – Convergent Dental Inc., a privately held dental device company, is proud to announce the significant milestones the company reached in 2014, the ...

Researchers discover brain circuit that controls compulsive overeating and sugar addiction

Compulsive overeating and sugar addiction are major threats to human health, but potential treatments face the risk of impairing normal feeding behaviors that are crucial for survival. A study publish...

Identified the mechanism that controls localization of protein Rac1 in the cell nucleus

The sustained presence in the nucleus of the protein known as Rac1 produces changes in nuclear morphology that are important in several biological processes, including malignant cancer. This is the fi...

China’s Healthcare Sector Set for Foreign Investment Explosion

Foreign Direct Investment (FDI) into China's life sciences sector will increase by 177% to £128.2 billion by 2020, as the rapidly ageing population drives demand for healthcare services and the Chine...

International Stem Cell Corporation to Conduct Parkinson's Disease Clinical Study in Australia

CARLSBAD, CA--(Marketwired - January 29, 2015) - International Stem Cell Corporation (OTCQB: ISCO), a California-based biotechnology company developing novel stem cell based therapies and biomedical p...

New Evidence Shows Genetic Testing May Help Target Use of Antidepressants

KING OF PRUSSIA, PA--(Marketwired - January 29, 2015) - Clinical depression is a common problem affecting over 16% of Americans at some time in their lives. While antidepressants are among the most co...

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Companies [33 Associated Companies listed on BioPortfolio]

Digital Lumens

Digital Lumens is a global supplier of enterprise-scale intelligent LED lighting to commercial and industrial customers, delivering 90% energy savings and granular building intell...

SageGlass

SageGlass®, a product of Saint-Gobain, is advanced dynamic glass that can be electronically tinted or cleared to optimize daylight and improve the human experience in buildings...

Linnea SA

Located in the Swiss canton of Ticino, Linnea is a high-quality manufacturer of active ingredients for use in the health food and cosmetic industries and pharmaceutical industries...

AsiaInspection

Founded in Hong Kong, AsiaInspection (www.asiainspection.com) is the leading online platform for performing product inspections, testing and factory audits in Asia for impor...

22nd Century Group, Inc.

Founded in 1998, 22nd Century Limited, LLC (22nd Century) is a plant biotechnology company whose proprietary technology allows for the level of nicotine (and other nicotinic alkal...

Daylight Solutions, Inc.

Daylight Solutions develops molecular detection, imaging and high-power illumination systems for use in industrial process controls, scientific research, medical diagnostics, envi...

China Kangtai Cactus Bio-tech Inc.

China Kangtai Cactus Bio-tech, Inc. is a leading grower, developer, producer, and marketer of cactus-derived products, including nutraceuticals, nutritious food, health and energy...

China Kangtai Cactus Bio-tech, Inc.

China Kangtai Cactus Bio-tech, Inc. is a leading grower, developer, producer, and marketer of cactus-derived products, including nutraceuticals, nutritious food, health and energy...

Vendormate, Inc.

Vendormate protects the health of supply chains with a unique vendor credentialing and compliance monitoring solution. The program assures compliance with both internal policies and government mandate...

China Kangtai Cactus Biotech Inc.

China Kangtai Cactus Biotech, Inc. is a leading grower, developer, producer, and marketer of cactus-derived products, including nutraceuticals, nutritious food, health and energy ...

Clinical Trials [582 Associated Clinical Trials listed on BioPortfolio]

Study for the Early Diagnosis of Parkinson's Disease

The main objective of the study is to design and validate the blood based PDx gene expression assay for the early diagnosis of Parkinson's disease patients. Differential diagnosis include...

A Pilot Study to Investigate Biomarkers in Anterior Cruciate Ligament (ACL) Patients and Healthy Controls

Incident rates of ACL rupture are greatest in 16-39 year olds at almost 1 in 1,000. Performance Based Investigations (PBIs) can be used to evaluate and select correct approaches to patien...

Clinical Trial in Constitutional Thinness

The purpose of this study is to evaluate the molecular differences between a group of Constitutionally Thin (CT) subjects and a group of controls.

Influence of Corn Farming on the Immune System

This study will look for links between corn farming practices and short-term changes in immune function in farmers throughout the growing season. It will examine biologic effects associate...

Genetic Susceptibility to Childhood Respiratory IIlness in Mexico City

We propose to add a collection of genetic material to a clinical trial of anti-oxidant supplementation for the amelioration of asthma in 7-12 year olds being conducted at a public pediatri...

Fatty Acids, Genes and Microbiota in Fatty Liver

The first aim of this study is to assess oxidative stress and nutritional status in patients with elevated liver enzymes who were found to have either simple steatosis (SS) or nonalcoholic...

A Case-Referent Study of Brain Tumors in Adults

The etiology of brain tumors is poorly understood. Due, in part, to public concern about a postulated relationship between the use of cellular telephones or other increasingly prevalent e...

The Pharmacokinetics of Grazoprevir (MK-5172) and Elbasvir (MK-8742) in Participants With Renal Insufficiency (MK-5172-050)

Grazoprevir (MK-5172) and Elbasvir (MK-8742) are being studied as the principal components of combination oral therapy for hepatitis C virus (HCV). The study will examine the pharmacokinet...

Protein Synthesis in the Brain of Patients With Fragile X Syndrome

Biosynthesis of proteins is essential for growth and continued maintenance of the entire neuron including axons, dendrites, and synaptic terminals, and it is clearly one of the important b...

Physiological Investigations of Movement Disorders

Background: - Previous studies have given researchers information on how the brain controls movement, how people learn to make fine, skilled movements, and why some people have mo...

Medical and Biotech [MESH] Definitions

The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat.

A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

This area is bounded medially by the mammillothalamic tract and the anterior column of fornix. The medial edge of the internal capsule and the subthalamic region form its lateral boundary. It contains the lateral hypothalamic nucleus, tuberomammillary nucleus, lateral tuberal nuclei, and fibers of the MEDIAL FOREBRAIN BUNDLE. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p710)

The front portion of the HYPOTHALAMUS separated into the preoptic region and the supraoptic region. The preoptic region is made up of the periventricular gray matter of the rostral portion of the third ventricle and contains the preoptic ventricular nucleus and the medial preoptic nucleus. The supraoptic region contains the PARAVENTRICULAR HYPOTHALAMIC NUCLEUS, the SUPRAOPTIC NUCLEUS, the ANTERIOR HYPOTHALAMIC NUCLEUS, and the SUPRACHIASMATIC NUCLEUS.

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

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