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Hypothalamic Controls - Biotech, Pharma and Life Science Channel

09:08 EDT 26th March 2017 | BioPortfolio

PubMed Articles [4184 Associated PubMed Articles listed on BioPortfolio]

(123)IFP-CIT ENC-DAT normal database: the impact of the reconstruction and quantification methods.

[(123)I]FP-CIT is a well-established radiotracer for the diagnosis of dopaminergic degenerative disorders. The European Normal Control Database of DaTSCAN (ENC-DAT) of healthy controls has provided ag...

Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors.

Cannabinoid (CB) and opioid systems are both involved in analgesia, food intake, mood and behavior. Due to the co-localization of µ-opioid (MOR) and CB1 receptors in various regions of the central ne...

The seroprevalence of antithyroid peroxidase antibodies in bipolar families and bipolar twins: results from two longitudinal studies.

Previous studies of our group among bipolar offspring and bipolar twins showed significant higher prevalence's and levels of antithyroid peroxidase antibodies (TPO-Abs) in offspring and co-twins (with...

Effects of inference on dopaminergic prediction errors depend on orbitofrontal processing.

Dopaminergic reward prediction errors in monkeys reflect inferential reward predictions that well-trained animals can make when associative rules change. Here, in a new analysis of previously describe...

Gastric Fluid Volume Change After Oral Rehydration Solution Intake in Morbidly Obese and Normal Controls: A Magnetic Resonance Imaging-Based Analysis.

Although preoperative fluid intake 2 hours before anesthesia is generally considered safe, there are concerns about delayed gastric emptying in obese subjects. In this study, the gastric fluid volume ...

Lingual-Alveolar Contact Pressure During Speech in Amyotrophic Lateral Sclerosis: Preliminary Findings.

This preliminary study on lingual-alveolar contact pressures (LACP) in people with amyotrophic lateral sclerosis (ALS) had several aims: (a) to evaluate whether the protocol induced fatigue, (b) to co...

New Ways of Diagnosing ADHD in Adults.

Objective Diagnosing Attention-Deficit-Hyperactivity Disorder (ADHD) in adults requires that ADHD has already been present in childhood. However, recall of ADHD-symptoms in childhood is fallible, for ...

Fine Mapping of Chromosome 5p15.33 Identifies Novel Lung Cancer Susceptibility Loci in Han Chinese.

Genome-wide association studies in European and Asian populations have consistently identified chromosome 5p15.33 as a lung cancer susceptibility region. To investigate further the genetic architectur...

Multivalency Effect of TAT Peptide Functionalized Nanoparticle in Cellular Endocytosis and SubCellular Trafficking.

Although trans-activating transcription (TAT)-peptide functionalized nanoparticle/polymer/liposome is widely used for cellular transfection applications, the multivalency (number of attached peptide p...

Prospective evaluation of a week one overnight metyrapone test with subsequent dynamic assessments of hypothalamic-pituitary-adrenal axis function after pituitary surgery.

To determine if an overnight metyrapone test (OMT) within the first week post pituitary surgery can definitively assess the hypothalamic-pituitary-adrenal (HPA) axis, compared with subsequent dynamic ...

News Articles [609 Associated News Articles listed on BioPortfolio]

Increased insulin resistance found in patients with mild lupus

Patients with mild lupus had increased insulin resistance and hyperglucagonemia, while having normal glucose tolerance and a preserved beta-cell function and skeletal muscle GLUT-4 translocation, acco...

Electrical 'switch' in brain's capillary network monitors activity and controls blood flow

(Larner College of Medicine at the University of Vermont) New research has uncovered that capillaries have the capacity to both sense brain activity and generate an electrical vasodilatory signal to e...

Control over production data still tripping up foreign drug manufacturers with FDA

Warning letters sent to two drugmakers in India and China show a lack of data controls and failure to investigate test results are still common problems with foreign suppliers. 

How does the body control stem cells? ‘It’s like a game of roulette’

Stem cells are unspecialized cells that can develop into any type of cell in the human body. So far, however, scientists only partially understand how the body controls the fate of these [cel

IL-36γ signaling controls the induced regulatory T cell–Th9 cell balance via NFκB activation and STAT transcription factors

Reducing The Risks To Your Brain

The brain is the most important organ in the body. It controls the function of every other body system, and it provides storage for our... Read More →

$5.5 Million Settlement Related to Audit Controls

In a case that highlights the need for proper audit controls, Florida’s Memorial Healthcare System (MHS) has paid the U.S. Department of Health and Human Services (HHS) $5.5 million to settle po...

How the nervous system controls tumor growth

(Medical Xpress)—From the time it first comes online during development the nervous system begins to exact precise control over many biologic functions. In some cases, too much control. When it does...

Endocrine Society experts issue Clinical Practice Guideline on hypothalamic amenorrhea

(The Endocrine Society) Female athletes and women who have eating disorders are prone to developing a condition called hypothalamic amenorrhea that causes them to stop menstruating. The Endocrine Soci...

FDA Use Fee Hearing Hijacked By US Health Care Reform Arguments

Democrats argue generic competition alone cannot fix drug pricing problem as senators attempt to pull FDA into Obamacare repeal and...   

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Companies [43 Associated Companies listed on BioPortfolio]

Kyriba Corp.

Kyriba is the global leader in cloud treasury solutions, delivering Software-as-a-Service (SaaS) treasury technology to corporate CFOs and Treasurers. More than 1,300 global organ...

Alfresco Software

Alfresco provides modern enterprise content management (ECM) software built on open standards that enables organizations to unlock the power of their business-critical content. Wi...

Excel Dryer, Inc.

For over 50 years, Excel Dryer has been manufacturing the finest American made hand dryers featuring the XLERATOR® Hand Dryer. Excel Dryer is a family owned and operated compan...

Voxello, Inc.

Voxello provides solutions for disabled hospitalized patients who cannot communicate by traditional means. The company’s first product, the noddle™, allows disabled pati...

Degree Controls, Inc.

Indigo-Clean

Indigo-Clean is an affiliate of Kenall Manufacturing, which has earned a reputation for superior quality, innovation, sustainability and exceptional value in the lighting industry...

Intermatic Incorporated

Intermatic has delivered quality products and service to its customers for over 100 years. As a leading manufacturer of controls and energy-management solutions for electrical, HV...

Xamin, Inc.

Founded in 1999, Xamin, Inc. is a Chicago based company offering industry leading IT services to financial institutions as well as other highly regulated industries. The company p...

NanoSpeed Diagnostics, Inc.

DiaSys Diagnostic Systems is a leading specialist in the development and manufacturing of diagnostic system solutions of highest quality, trusted by customers in more than 100 cou...

Phytecs

Phytecs develops healthcare and nutrition products targeting the endocannabinoid system responsible for the regulation of nearly every physiologic process within the human ...

Clinical Trials [1006 Associated Clinical Trials listed on BioPortfolio]

Emotional Brain Networks & Cognitive Functioning in Depression and Anxiety

This study aims to 1) examine common and specific emotional and cognitive dysfunctions between Major Depression and generalized anxiety disorder; 2) Examine emotional and cognitive dysfunc...

The Effect of GIP and GLP-1 on Insulin and Glucagon Secretion in Patients With HNF1A-diabetes Treated With or Without Sulphonylurea

The most prevalent monogenetic diabetic subtype is named maturity onset diabetes of the young type (MODY3) or hepatocyte nuclear factor 1α (HNF1A)-diabetes. The aim of this study is to ev...

Migraine and CVD Risk in Women

The primary goal of this study is to test the effects of a high-fat, high-carbohydrate mixed meal on candidate modulators of cardiovascular disease risk (inflammation, vascular reactivity,...

The Effect of Nutrient Intake on the Microbiome, Weight, and Glucoregulation (NI-MWG)

The purpose of this study is to investigate a persons dietary intake and its effect on the gut microbiome and the association of those two variables on weight and glucoregulation. Specific...

Development of Imaging Biomarkers for Voice After Pediatric Airway Reconstruction

Objective: The purpose of this proposal is to use High Speed Videoendoscopy (HSV) to develop and test an imaging biomarker to support diagnosis and predict vibratory outcome after airway ...

Utility of Cortical Bone Tissue Properties in the Assessment of Fracture Risk

The objective of this study is to determine whether a new minimally invasive method for in vivo measurement of cortical bone tissue properties can identify those who are at risk for fragil...

Atomoxetine, Diurnal Profiles of Cortisol and α-amylase

Diurnal profiles of markers of the stress system are increasingly recognized as biomarkers of different kinds of depression and related states. They may also serve as markers of treatment ...

Homeostatic and Non-homeostatic Processing of Food Cues in Anorexia Nervosa

The goal of the present study is to investigate metabolic gut-brain signaling and the neural correlates of distraction from visual food cues in patients with Anorexia nervosa and healthy c...

Safety and Efficacy of Intravitreal Injection of Human REtinal Progenitor Cells in Adults With Retinitis Pigmentosa

This study evaluates the changes in visual function at 12 months following a single injection of human retinal progenitor cells compared to untreated controls in a cohort of adult subjects...

Effect of Ergocalciferol on Iron Metabolism in Individuals With Chronic Kidney Disease

The purpose of the study is to learn more about how treatment with vitamin D can affect iron metabolism and blood levels of hepcidin (hormone controlling iron levels) in people with chroni...

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Medical and Biotech [MESH] Definitions

The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat.

A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

This area is bounded medially by the mammillothalamic tract and the anterior column of fornix. The medial edge of the internal capsule and the subthalamic region form its lateral boundary. It contains the lateral hypothalamic nucleus, tuberomammillary nucleus, lateral tuberal nuclei, and fibers of the MEDIAL FOREBRAIN BUNDLE. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p710)

The front portion of the HYPOTHALAMUS separated into the preoptic region and the supraoptic region. The preoptic region is made up of the periventricular gray matter of the rostral portion of the third ventricle and contains the preoptic ventricular nucleus and the medial preoptic nucleus. The supraoptic region contains the PARAVENTRICULAR HYPOTHALAMIC NUCLEUS, the SUPRAOPTIC NUCLEUS, the ANTERIOR HYPOTHALAMIC NUCLEUS, and the SUPRACHIASMATIC NUCLEUS.

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

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