Hypothalamic Controls - Biotech, Pharma and Life Science Channel

18:01 EDT 27th May 2015 | BioPortfolio

PubMed Articles [4245 Associated PubMed Articles listed on BioPortfolio]

Incorporation of antimicrobial peptides on functionalized cotton gauzes for medical applications.

A large group of low molecular weight natural compounds that exhibit antimicrobial activity has been isolated from animals and plants during the past two decades. Among them, peptides are the most wid...

Fibrin supports human fetal islet-epithelial cell differentiation via p70(s6k) and promotes vascular formation during transplantation.

The human fetal pancreas expresses a variety of extracellular matrix (ECM) binding receptors known as integrins. A provisional ECM protein found in blood clots that can bind to integrin receptors and ...

Genetic variants in matrix metalloproteinase genes as disposition factors for ovarian cancer risk, survival, and clinical outcome.

Ovarian cancer is one of the leading female cancers in the United States. Challenges remain in early diagnosis of this deadly disease. Matrix metalloproteinases (MMPs) family genes are paradoxically i...

A preliminary candidate approach identifies the combination of chemerin, fetuin-A, and fibroblast growth factors 19 and 21 as a potential biomarker panel of successful aging.

Although the number of centenarians is growing worldwide, the potential factors influencing the aging process remain only partially elucidated. Researchers are increasingly focusing toward biomarkers ...

Prenatal exposure to aflatoxin B1: developmental, behavioral, and reproductive alterations in male rats.

Previous studies have shown that aflatoxin B1 (AfB1) inhibits androgen biosynthesis as a result of its ability to form a high-affinity complex with the steroidogenic acute regulatory protein. The resu...

A new pathway in the control of the initiation of puberty: the MKRN3 gene.

Pubertal timing is influenced by complex interactions among genetic, nutritional, environmental, and socioeconomic factors. The role of MKRN3, an imprinted gene located in the Prader-Willi syndrome cr...

Inhibition of Growth and Metastasis of Breast Cancer in Mice by Milk Fermented With Lactobacillus casei CRL 431.

Breast cancer is the second cause of death in women, who are especially related to uncontrolled metastasis. It was previously demonstrated that the administration of milk fermented by Lactobacillus ca...

Discovery and longitudinal evaluation of candidate protein biomarkers for disease recurrence in prostate cancer.

When compared with hormonal therapy alone, treatment with combined hormone and radiation therapy (CHRT) gives improved disease-specific survival outcomes for patients with prostate cancer. However, a ...

Combinations of Susceptibility Genes Are Associated with Higher Risk for Multiple Sclerosis and Imply Disease Course Specificity.

Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that predominantly affects young adults. The genetic contributions to this multifactorial disease were underscored...

QM/MM Calculated Reactivity Networks Reveal How Cytochrome P450cam and Its Celebrated Mutant Select Their Oxidation Pathways.

QM/MM calculations address the longstanding-question of a "second oxidant" in P450 enzymes wherein the proton-shuttle, which leads to formation of the "primary-oxidant" Compound I (Cpd I), was severed...

News Articles [503 Associated News Articles listed on BioPortfolio]

Canadian International Pharmacy Association (CIPA) Survey of Americans Finds 64% Purchase Medications from Canada Due to Affordability

WINNIPEG, Manitoba, May 27, 2015 /PRNewswire-USNewswire/ -- In a new survey of approximately 2,700 American customers, the Canadian International Pharmacy Association (CIPA) found continued deman...

Combined contraceptive pills 'increase risk of blood clots'

"Women who take the latest generations of contraceptive pills are at a greater risk of potentially lethal blood clots," The Times reports. While the increase in risk is statistically signifi...

English language checks 'may harm' overseas recruitment

Concerns have been raised that new English language controls for European Union nurses and midwives seeking to join the UK register could hamper overseas recruitment efforts by the NHS.

May is National Mobility Awareness Month: Tips for Coping with a New Disability

May is National Mobility Awareness Month and NMEDA helps spread the word about living an active and mobile lifestyle.There are multiple options for adaptive vehicle equipment on the market to cope wit...

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert

A unique property of many adult stem cells is their ability to exist in a non-cycling, quiescent state. Although quiescence serves an essential role in preserving stem cell function until the stem cel...

A cascade of arabinosyltransferases controls shoot meristem size in tomato

Zachary Lippman and colleagues report mutations in the tomato ortholog of CLV1 and a gene encoding a hydroxyproline O-arabinosyltransferase enzyme that modifies CLV3, both of which cause fasciated flo...

NeuroBreak: Thought Controls Prosthetic, Loss of a Beautiful Mind

(MedPage Today) -- News and commentary from the world of neurology and neuroscience.

Controlling a Robotic Arm with a Patient's Intentions

Neural prosthetic devices implanted in the brain's movement center, the motor cortex, can allow patients with amputations or paralysis to control the movement of a robotic limb-one that can be either ...

TSC1 controls IL-1β expression in macrophages via mTORC1-dependent C/EBPβ pathway

Complex signaling between blood, stem cells controls regeneration in fly gut

Having a healthy gut may well depend on maintaining a complex signaling dance between immune cells and the stem cells that line the intestine. Scientists report significant new insight into how these ...

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Companies [37 Associated Companies listed on BioPortfolio]

Intermatic Incorporated

Intermatic has delivered quality products and service to its customers for over 100 years. As a leading manufacturer of controls and energy-management solutions for electrical, HV...

Xamin, Inc.

Founded in 1999, Xamin, Inc. is a Chicago based company offering industry leading IT services to financial institutions as well as other highly regulated industries. The company p...

NanoSpeed Diagnostics, Inc.

DiaSys Diagnostic Systems is a leading specialist in the development and manufacturing of diagnostic system solutions of highest quality, trusted by customers in more than 100 cou...

Phytecs

Phytecs develops healthcare and nutrition products targeting the endocannabinoid system responsible for the regulation of nearly every physiologic process within the human ...

Digital Lumens

Digital Lumens is a global supplier of enterprise-scale intelligent LED lighting to commercial and industrial customers, delivering 90% energy savings and granular building intell...

SageGlass

SageGlass®, a product of Saint-Gobain, is advanced dynamic glass that can be electronically tinted or cleared to optimize daylight and improve the human experience in buildings...

Linnea SA

Located in the Swiss canton of Ticino, Linnea is a high-quality manufacturer of active ingredients for use in the health food and cosmetic industries and pharmaceutical industries...

AsiaInspection

Founded in Hong Kong, AsiaInspection (www.asiainspection.com) is the leading online platform for performing product inspections, testing and factory audits in Asia for impor...

22nd Century Group, Inc.

Founded in 1998, 22nd Century Limited, LLC (22nd Century) is a plant biotechnology company whose proprietary technology allows for the level of nicotine (and other nicotinic alkal...

Daylight Solutions, Inc.

Daylight Solutions develops molecular detection, imaging and high-power illumination systems for use in industrial process controls, scientific research, medical diagnostics, envi...

Clinical Trials [620 Associated Clinical Trials listed on BioPortfolio]

Effectiveness of Internet-based Depression Treatment

Care for people suffering from depressive symptoms should be given in a step-wise approach. One first step can be the provision of self-help material. Online self-help is an innovative way...

Dynamic Plantar Microvascular Skin Response to Compressive Loads in At-risk Diabetic and Healthy Control: a Pilot Study

The purpose of this pilot study is to compare the dynamic response of microcirculation in the skin on the bottom of the big toe after applying controlled plantar stress in 25 diabetic subj...

A Safety And Pharmacokinetic Study of Setrobuvir Alone and In Combination With Ritonavir-Boosted Danoprevir in Subjects With Mild Hepatic Impairment Compared to Healthy Controls

This multi-center, fixed-sequence, open-label, multiple-dose, 2-period study will evaluate the safety, tolerability and pharmacokinetics of setrobuvir alone or in combination with ritonavi...

Tear Proteins, Conjunctival Cells and Imaging Eyes in Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients

Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE) are chronic systemic autoimmune diseases that have been reported to affect the ocular surface of patients [1,2]. However, t...

Study of Dopamine and Serotonin Transporters in Patients With Amyotrophic Lateral Sclerosis and Controls

The purpose of this study is to study the transporters of serotonin and dopamine in ALS patients in relation with the clinical phenotype, i.e., patients without stiffness, patients with py...

Epidemiology of Burkitt Lymphoma in East Africa Children or Minors (EMBLEM)

Burkitt lymphoma (BL) is an aggressive monoclonal B-cell malignancy that is rare (sporadic) worldwide, but is 100-fold more common (endemic) in equatorial Africa, particularly among childr...

Role of Neutrophil Activation in Anaphylaxis to Curare

In about 10% of preoperative anaphylactic reactions to curare (114 patients analyzed at the BICHAT Hospital), a classical mechanism (mast cell- and IgE-dependent) is not identified. The me...

Effect of Increasing Motor Cortex Inhibition on Task Specific Dystonia

Dystonia is a disease where muscles in the affected body part are abnormally active. This may result in abnormal postures. The underlying mechanisms are not known. One proposed mechanism ...

Day-case or Inpatient Care Following Inguinal Hernia Repair in Elderly Patients

The aim of the study was to evaluate the feasibility of day surgery for elderly patients undergoing elective open inguinal hernia repair. Medically stable patients aged 65 years or older, ...

Molecular Epidemiology of Dioxin-Related Illness in Seveso

In 1976 an accidental explosion in a chemical plant 16 miles north of Milan resulted in contamination of the local population with 2, 3, 7, 8-terachlorodibenzo-para-dioxin (TCDD). There is...

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Medical and Biotech [MESH] Definitions

The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat.

A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

This area is bounded medially by the mammillothalamic tract and the anterior column of fornix. The medial edge of the internal capsule and the subthalamic region form its lateral boundary. It contains the lateral hypothalamic nucleus, tuberomammillary nucleus, lateral tuberal nuclei, and fibers of the MEDIAL FOREBRAIN BUNDLE. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p710)

The front portion of the HYPOTHALAMUS separated into the preoptic region and the supraoptic region. The preoptic region is made up of the periventricular gray matter of the rostral portion of the third ventricle and contains the preoptic ventricular nucleus and the medial preoptic nucleus. The supraoptic region contains the PARAVENTRICULAR HYPOTHALAMIC NUCLEUS, the SUPRAOPTIC NUCLEUS, the ANTERIOR HYPOTHALAMIC NUCLEUS, and the SUPRACHIASMATIC NUCLEUS.

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

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