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Hypothalamic Controls - Biotech, Pharma and Life Science Channel

01:51 EST 25th February 2017 | BioPortfolio

PubMed Articles [4167 Associated PubMed Articles listed on BioPortfolio]

(123)IFP-CIT ENC-DAT normal database: the impact of the reconstruction and quantification methods.

[(123)I]FP-CIT is a well-established radiotracer for the diagnosis of dopaminergic degenerative disorders. The European Normal Control Database of DaTSCAN (ENC-DAT) of healthy controls has provided ag...

Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors.

Cannabinoid (CB) and opioid systems are both involved in analgesia, food intake, mood and behavior. Due to the co-localization of µ-opioid (MOR) and CB1 receptors in various regions of the central ne...

The seroprevalence of antithyroid peroxidase antibodies in bipolar families and bipolar twins: results from two longitudinal studies.

Previous studies of our group among bipolar offspring and bipolar twins showed significant higher prevalence's and levels of antithyroid peroxidase antibodies (TPO-Abs) in offspring and co-twins (with...

Effects of T-2 Toxin on Pacific White Shrimp Litopenaeus vannamei: Growth, and Antioxidant Defenses and Capacity and Histopathology in the Hepatopancreas.

Modified-masked T-2 toxin (mT-2) formed during metabolism in edible aquatic animals may go undetected by traditional analytical methods, thereby underestimating T-2 toxicity. The effects of T-2 on gro...

Cardiac findings in Quarter Horses with heritable equine regional dermal asthenia.

OBJECTIVE To compare biomechanical and histologic features of heart valves and echocardiographic findings between Quarter Horses with and without heritable equine regional dermal asthenia (HERDA). DES...

UCP2 Expression Is Increased in Pancreas From Brain-Dead Donors and Involved in Cytokine-Induced β Cells Apoptosis.

Systemic inflammation associated with brain death (BD) decreases islet yield and quality, negatively affecting outcomes of human islet transplantation. A recent study from our group showed an increase...

Dynamic control of chirality and self-assembly of double-stranded helicates with light.

Helicity switching in biological and artificial systems is a fundamental process that allows for the dynamic control of structures and their functions. In contrast to chemical approaches to responsive...

Signalling crosstalk at the leading edge controls tissue closure dynamics in the Drosophila embryo.

Tissue morphogenesis relies on proper differentiation of morphogenetic domains, adopting specific cell behaviours. Yet, how signalling pathways interact to determine and coordinate these domains remai...

Depressive symptoms in HIV-infected and seronegative control subjects in Cameroon: Effect of age, education and gender.

Depression is a leading cause of HIV/AIDS disease burden; it worsens health outcomes and quality of life. Addressing this problem requires accurate quantification of the extra burden of depression to ...

rEHR: An R package for manipulating and analysing Electronic Health Record data.

Research with structured Electronic Health Records (EHRs) is expanding as data becomes more accessible; analytic methods advance; and the scientific validity of such studies is increasingly accepted. ...

News Articles [621 Associated News Articles listed on BioPortfolio]

MGH researchers discover regulators of gene expression programs in medulloblastoma

Massachusetts General Hospital researchers have identified a mechanism that controls the expression of genes regulating the growth of the most aggressive form of medulloblastoma, the most common pedia...

Molecular 'on switch' could point to treatments for pediatric brain tumor

Massachusetts General Hospital (MGH) researchers have identified a mechanism that controls the expression of genes regulating the growth of the most aggressive form of medulloblastoma, the most common...

Commercial Electronic Flight Bag Market by Type Portable EFB and Installed EFB, Component Hardware: Class 1, Class 2, and Class 3, Software: Type A, Type B, and Type C, and Geography Forecast 2015 to 2020 Prices from USD $5650

The electronic flight bag market is estimated at $2.28 billion in 2015 and is expected to register a CAGR of 13.41% to reach $4.27 billion by 2020.The report provides a market analysis of the EFB mark...

Watching how ‘young’ cells move gives clues on skin cancer spread

Science blog We all start life as a fertilised egg, but for this to develop into an embryo each cell has to go through a step-by-step process. It’s a carefully choreographed journey that combines...

FDA allows marketing of test to identify organisms that cause bloodstream infections and provide antibiotic sensitivity results

SILVER SPRING, Md., Feb. 23, 2017 /PRNewswire-USNewswire/ -- The U.S. Food and Drug Administration today allowed marketing of the PhenoTest BC Kit, performed on the Pheno System. This is the first tes...

L&T Technology Services Limited & UTC Commercial Businesses Establish Innovation Lab for Intelligent Buildings, Connected Homes and Cold Chain Logistics

L&T Technology Services Limited (NSE: LTTS), a leading global pure-play engineering R&D services company,and UTC Climate, Controls Security and Otis, units of United Technologies Corp. (NYSE: UTX)...

Corticosteroids increased testosterone deficiency in patients with lupus

Patients with lupus who used corticosteroids had higher levels of luteinizing hormone and more frequent bioactive testosterone deficiency compared with the general population, according to recently pu...

Complement drives glucosylceramide accumulation and tissue inflammation in Gaucher disease

Gaucher disease is caused by mutations in GBA1, which encodes the lysosomal enzyme glucocerebrosidase (GCase). GBA1 mutations drive extensive accumulation of glucosylceramide (GC) in multiple innate a...

Changes in brain connectivity can help diagnose and predict outcomes of mild TBI

A new study shows that patients with mild traumatic brain injury (mTBI), even without evidence of brain lesions, may exhibit changes in brain connectivity detectable at the time of the injury that can...

Monaghan's drug-free Aerobika(R) device helps reduce the real-world impact of exacerbations in chronic obstructive pulmonary disease

SYRACUSE, NY -- (Marketwired) -- 02/23/17 -- Monaghan Medical Corporation (MMC) today announced the publication of a study in Pulmonary Therapy showing that treatment with Monaghan's Aerobika® devic...

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Companies [43 Associated Companies listed on BioPortfolio]

Kyriba Corp.

Kyriba is the global leader in cloud treasury solutions, delivering Software-as-a-Service (SaaS) treasury technology to corporate CFOs and Treasurers. More than 1,300 global organ...

Alfresco Software

Alfresco provides modern enterprise content management (ECM) software built on open standards that enables organizations to unlock the power of their business-critical content. Wi...

Excel Dryer, Inc.

For over 50 years, Excel Dryer has been manufacturing the finest American made hand dryers featuring the XLERATOR® Hand Dryer. Excel Dryer is a family owned and operated compan...

Voxello, Inc.

Voxello provides solutions for disabled hospitalized patients who cannot communicate by traditional means. The company’s first product, the noddle™, allows disabled pati...

Degree Controls, Inc.

Indigo-Clean

Indigo-Clean is an affiliate of Kenall Manufacturing, which has earned a reputation for superior quality, innovation, sustainability and exceptional value in the lighting industry...

Intermatic Incorporated

Intermatic has delivered quality products and service to its customers for over 100 years. As a leading manufacturer of controls and energy-management solutions for electrical, HV...

Xamin, Inc.

Founded in 1999, Xamin, Inc. is a Chicago based company offering industry leading IT services to financial institutions as well as other highly regulated industries. The company p...

NanoSpeed Diagnostics, Inc.

DiaSys Diagnostic Systems is a leading specialist in the development and manufacturing of diagnostic system solutions of highest quality, trusted by customers in more than 100 cou...

Phytecs

Phytecs develops healthcare and nutrition products targeting the endocannabinoid system responsible for the regulation of nearly every physiologic process within the human ...

Clinical Trials [989 Associated Clinical Trials listed on BioPortfolio]

Metabolomics Study of Cardiomyopathy

This study aims to 1)characterize the differentially expressed metabolites between cardiomyopathy patients and healthy controls,2)identify the specific biomarkers associated with outcomes ...

The Gut Microbiota of Bipolar and Depression

Background: The gut microbiome is emerging as an important factor in regulating mental health yet it remains unclear what the target should be for psychiatric treatment. Investigators aim ...

The Impact of Structured Exercise on Brain Health in HIV Positive Individuals

Exercise programs that combine resistance exercise with aerobic training yield optimal health benefits for people with HIV. The global aim of this study is to contribute evidence for the i...

Inflammatory Biomarkers and Brain Metabolites, a Study Based on Magnetic Resonance Spectroscopy

Suicidal behaviors (SB) are a major health problem in France : 10 000 suicides and 220 000 suicide attempts every year. SB management is therefore a major public health issue. Evidence as...

Video-Feedback Interaction Guidance for Improving Interactions Between Depressed Mothers and Their Infants ("VID-KIDS")

Postpartum depression (PPD) is a major public health issue. Known as "the thief that steals motherhood" since symptoms obstruct a mother's capacity for understanding and enjoying her baby,...

Combined Replacement Therapy With Levothyroxine and Liothyronine in Thyroidectomized Patients

The aim of the study is to evaluate the peripheral tissue response to the combined administration of levothyroxine (LT4) and liothyronine (LT3) in hypothyroid patients with residual thyroi...

Pain Mechanisms in Young Adolescent Females With Longstanding Patellofemoral Pain

Patellofemoral pain (PFP) is a highly prevalent musculoskeletal condition in adult females, which is associated with decreased quality of life and physical activity levels. PFP is highly p...

Does Participation in a Pre-Operative Physical Activity Program Improve Patient Outcomes and Quality of Life?

The primary objective of the study is to determine whether participation in a pre-bariatric surgery physical activity and behavior modification/education program (ENCOURAGEING START) that ...

Reactivity of the Vestibular System to Caloric Vestibular Stimulation in Schizophrenia

This study aims to determine if individuals with schizophrenia have greater reactivity to vestibular stimulation than healthy controls. The physiological response of vestibular stimulation...

Metabolomics and Genetic Diagnosing Pancreatic Neuroendocrine Tumors in MEN1 Patients

Objectives: The aim of the present study is to assess the significance of metabolomics and genetics in diagnosing and survival evaluation for pNET in the periodic follow-up of MEN1 patien...

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Medical and Biotech [MESH] Definitions

The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat.

A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

This area is bounded medially by the mammillothalamic tract and the anterior column of fornix. The medial edge of the internal capsule and the subthalamic region form its lateral boundary. It contains the lateral hypothalamic nucleus, tuberomammillary nucleus, lateral tuberal nuclei, and fibers of the MEDIAL FOREBRAIN BUNDLE. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p710)

The front portion of the HYPOTHALAMUS separated into the preoptic region and the supraoptic region. The preoptic region is made up of the periventricular gray matter of the rostral portion of the third ventricle and contains the preoptic ventricular nucleus and the medial preoptic nucleus. The supraoptic region contains the PARAVENTRICULAR HYPOTHALAMIC NUCLEUS, the SUPRAOPTIC NUCLEUS, the ANTERIOR HYPOTHALAMIC NUCLEUS, and the SUPRACHIASMATIC NUCLEUS.

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

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