Hypothalamic Controls - Biotech, Pharma and Life Science Channel
PubMed Articles
The influence of genetic polymorphisms in MDR1 gene on breast cancer risk factors in Chinese.
Breast cancer (BC) is the most common cancer among women in the world. The human multidrug resistance 1 gene (MDR1) is potentially an important gene influencing the susceptibility to breast cancer. Th...
CYP2A6, CYP1A1, and CYP2D6 polymorphisms in lung cancer patients from Central South China.
Lung cancer is a common cause of cancer-related death. The link between risk of lung cancer susceptibility and genetic polymorphisms in metabolic enzymes is well documented. In this study, the relatio...
Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults in Western countries. It is characterized by heterogeneous clinical course of the disease and new prognostic factors are still...
The glucocorticoid receptor (GR) and corticotropin-releasing hormone (CRH) are important molecular regulators of an individual's ability to respond to stressful stimuli in an adaptive manner. Impaired...
Passive stiffness of the gastrocnemius muscle in athletes with spastic hemiplegic cerebral palsy.
The passive properties of the muscle-tendon unit are regularly assessed in individuals with cerebral palsy (CP). However, no information is available on the passive properties of adult muscle, and whe...
Pheromones from urine of unfamiliar conspecific male animals can re-initiate a female's estrus cycle to cause pregnancy block through the vomeronasal organ (VNO)-accessory olfactory bulb (AOB)-hypotha...
IL-22-producing CD4+ cells are depleted in actively inflamed colitis tissue.
T helper type (Th17) cytokines such as interleukin (IL)-17A and IL-22 are important in maintaining mucosal barrier function and may be important in the pathogenesis of inflammatory bowel diseases (IBD...
Adenosine A2A receptors in secondary progressive multiple sclerosis: a (11)CTMSX brain PET study.
In this study, positron emission tomography (PET) imaging with a radioligand to adenosine A2A receptors (A2AR)-a potent regulator of inflammation-was used to gain insight into the molecular alteration...
Live imaging reveals active infiltration of mitotic zone by its stem cell niche.
Stem cells niches are increasingly recognized as dynamic environments that play a key role in transducing signals that allow an organism to exert control on its stem cells. Live imaging of stem cell n...
Objective. The aim of this study was to determine the protein-calorie nutritional status of elderly hospitalized patients admitted to the hepato-gastroenterology, cardiology and internal medicine depa...
News Articles
Negligible impact of rare autoimmune-locus coding-region variants on missing heritability
Genome-wide association studies (GWAS) have identified common variants of modest-effect size at hundreds of loci for common autoimmune diseases; however, a substantial fraction of heritability remains...
Researchers identify new target to boost plant resistance to insects and pathogens
(Cell Press) Plants have evolved unique and sophisticated immune systems to defend themselves against insects and pathogens. Plant hormones called jasmonates play an important role in this defense, bu...
Molecular biology: Small RNA tunes protein
A small RNA molecule that controls whether bacteria coalesce into biofilms has a surprising mode of action.Small RNAs are known to regulate gene expression by binding to target messenger RNAs, typical...
Superior Controls of Seabrook, NH named Business of the Year for 2013 by Business NH Magazine
SEABROOK, N.H., May 22, 2013 /PRNewswire/ -- Superior Controls, Inc. has been named "Manufacturing/Technology Business of the Year 2013" by Business NH Magazine. For the past 22 years, the...
Multiple Target ALS Drug Ready for Genervon's Phase 2 Trial
Multiple targets, highly effective, breakthrough therapy for ALS sufferers may now be within reach. Winston Ko, the CEO of Genervon Biopharmaceuticals, will be presenting on Frida...
Hypothalamic glucagon signaling inhibits hepatic glucose production
Glucagon has traditionally been thought to act exclusively on the liver to promote endogenous glucose production in that organ. Tony Lam and his colleagues now show that it also acts on the hypothalam...
India's New Price Controls To Hit 652 Essential Drugs, Cutting Profits
India's new list of price-regulated essential drugs set to take effect in mid-June will cover 652 bulk drugs and their formulations, with GlaxoSmithKline and Sanofi Aventis to be the most adversely af...
Eps8 controls dendritic spine density and synaptic plasticity through its actin-capping activity
Eps8 controls dendritic spine density and synaptic plasticity through its actin-capping activityReduced Eps8 levels in brains of autism patients correlate with impaired spine morphogenesis and cogniti...
Natural GMOs Part 164, Carnivorous plant has deleted most of its junk DNA
Common bladdertwort-Creative Commons Wikipedia,
NextPharma Technologies Holding Limited, one of the leading contract manufacturers in Europe for the pharmaceutical, biotechnology and healthcare industries, is delighted to annou...
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Companies
China Kangtai Cactus Bio-tech, Inc.
China Kangtai Cactus Bio-tech, Inc. is a leading grower, developer, producer, and marketer of cactus-derived products, including nutraceuticals, nutritious food, health and energy...
China Kangtai Cactus Bio-tech Inc.
China Kangtai Cactus Bio-tech, Inc. is a leading grower, developer, producer, and marketer of cactus-derived products, including nutraceuticals, nutritious food, health and energy...
Daylight Solutions develops molecular detection, imaging and high-power illumination systems for use in industrial process controls, scientific research, medical diagnostics, envi...
Acuity Brands, Inc. is a North American market leader and one of the worldâs leading providers of luminaires, lighting control systems and related products and services with...
InvenSense Inc. (NYSE: INVN) is the leading provider of MotionTrackingâ¢Â solutions for consumer electronic devices in the world. The companyâs patented Nasiri-Fabricati...
Xceedium is the leading provider of privileged identity and access management solutions for hybrid-cloud enterprises. Large companies and global government agencies use Xceedium p...
SAGE Electrochromics is the worldâs leading manufacturer of advanced dynamic glass that can be tinted or cleared to optimize daylight and improve the human experience in buil...
InvenSense Inc. (NYSE: INVN) is the worldâs leading provider of MotionTrackingâ¢Â solutions for consumer electronic devices. The companyâs patented NF Platfo...
Orthovita, Inc. is a specialty spine and orthopedic company with a portfolio of orthobiologic and biosurgery products. Our products are based on novel and unique proprietary bioma...
China Kangtai Cactus Biotech, Inc.
China Kangtai Cactus Biotech, Inc. is a leading grower, developer, producer, and marketer of cactus-derived products, including nutraceuticals, nutritious food, health and energy...
Clinical Trials
Hip Pathomorphology in Collegiate Athletes and Controls
In a previous study, the investigators have shown that 95% of the University of Utah football players had at least one radiographic abnormality consistent of FAI (IRB #40479). Siebenrock e...
Host Immune Response to Clostridium Difficile Infection in Inflammatory Bowel Disease Patients
The inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn's disease (CD) are chronic conditions affecting approximately 1.4 million Americans. The burden of Clostridium dif...
Scleroderma is an autoimmune disease of unknown origin. Recently, the role of environmental factors, and particularly toxic drug exposure, in the genesis of scleroderma has been suggested....
Risk Factors for Gastric Disease in Pediatric Helicobacter Pylori (H. Pylori)
Helicobacter pylori (Hp) is a major cause of chronic-active gastritis and primary duodenal ulcers, and is strongly linked to gastric cancer. Most Hp infections worldwide are acquired in c...
Randomized clinical study of two CAM therapies, 1) Reiki and 2) Relaxation Response Therapy with Cognitive Restructuring counseling (RRT with CR), compared to an education-only control arm...
Lactate Metabolism Study in HIV Infected Persons
Lactic acidosis is a potentially life-threatening disease associated with the treatment of chronic HIV infection. Although acidosis is rare, hyperlactatemia is common and may have long ter...
Leipzig Exercise Intervention in Chronic Heart Failure and Aging
In both ageing and heart failure progressive exercise intolerance is observed. The Leipzig Exercise Intervention in Chronic heart failure and Aging (LEICA) study aims to investigate how ae...
Prevention of Contrast-Induced Nephropathy
Patients with pre-existing kidney disease are at high risk of acute renal failure when exposed to radio-contrast dyes, for example during a cardiac angiogram. The investigators hypothesiz...
The primary objective of this proposed research is to improve the quality of care for patients who present to the Emergency Department with osteoporosis and a fracture of the wrist, by inc...
Morphology of the VMO in Patients With PFPS and Healthy Young Adults--A Sonographic Study
Background：Patellofemoral pain syndrome（PFPS） is a common knee disorder characterized by anterior or retropatellar pain associated with activities that load the patellofemoral joint....
Videos
How the Body Works : Anatomy of the Hypothalamus
How the Body Works Anatomy of the Hypothalamus Connected by many nerve tracts with the brain and spinal cord, the hypothalamus acts as a link between the end...
Medical and Biotech [MESH] Definitions
Pituitary Adenylate Cyclase-activating Polypeptide
A multi-function neuropeptide that acts throughout the body by elevating intracellular cyclic AMP level via its interaction with PACAP RECEPTORS. Although first isolated from hypothalamic extracts and named for its action on the pituitary, it is widely distributed in the central and peripheral nervous systems. PACAP is important in the control of endocrine and homeostatic processes, such as secretion of pituitary and gut hormones and food intake.
Nuclear Respiratory Factor 1
A transcription factor that controls the expression of variety of proteins including CYTOCHROME C and 5-AMINOLEVULINATE SYNTHETASE. It plays an important role in maintenance of the RESPIRATORY CHAIN of MITOCHONDRIA.
Hepatocyte Nuclear Factor 3-gamma
A winged-helix transcription factor that regulates GENE expression in metabolic tissues. It plays a role in HOMEOSTASIS of GLUCOSE and controls expression of GLUT2 PROTEIN.
Early Growth Response Protein 2
An early growth response transcription factor that controls the formation of the MYELIN SHEATH around peripheral AXONS by SCHWANN CELLS. Mutations in EGR2 transcription factor have been associated with HEREDITARY MOTOR AND SENSORY NEUROPATHIES such as CHARCOT-MARIE-TOOTH DISEASE.
Pallister-hall Syndrome
A pleiotropic disorder of human development that comprises hypothalamic HAMARTOMA; central and postaxial POLYDACTYLY; bifid EPIGLOTTIS; ANAL ATRESIA; and renal and other abnormalities. This disorder is associated with FRAMESHIFT MUTATIONS in the GLI3 gene which encodes the GLI3 protein, a KRUPPEL-LIKE TRANSCRIPTION FACTORS family member.
