Idiopathic Interstitial Pneumonias - Biotech, Pharma and Life Science Channel
PubMed Articles
Although intestinal microbiota are essential for the development of T cell-mediated colitis, it remains undetermined whether they enhance or suppress the chronic extraintestinal inflammation that ofte...
Exercises for Adolescent Idiopathic Scoliosis: A Cochrane Systematic Review.
STUDY DESIGN.: Systematic review of interventions. OBJECTIVE.: To evaluate the efficacy of scoliosis-specific exercise (SSE) in adolescent patients with adolescent idiopathic scoliosis (AIS). SUMMARY...
Spondyloarthritis and inflammatory bowel disease : Comorbidity and treatment implications.
Spondyloarthritides (SpA) and inflammatory bowel disease (IBD) are chronic, idiopathic inflammatory disorders of the axial and peripheral joints and the intestinal tract, respectively, affecting up to...
Breakthrough pain and short-acting opioids.
Conventional opioid therapy consists of the regular administration of extended-release opioids following fixed time intervals and, as needed, the supplemental use of an immediate-release formulation....
Rotating-shield brachytherapy for cervical cancer.
In this treatment planning study, the potential benefits of a rotating shield brachytherapy (RSBT) technique based on a partially-shielded electronic brachytherapy source were assessed for treating ce...
Oxygen doped SiC nanocrystals: first principles study of the optical properties.
We have studied a typical spherical SiC nanocrystal with a diameter of 1.2 nm (Si43C44H76) using linear combination of atomic orbitals in combination with pesudopotential density functional calculati...
Zyxin Regulates Cell Migration and Differentiation in EMT during Chicken AV Valve Morphogenesis.
During heart valve development, epithelial-mesenchymal transformation (EMT) is a key process for valve formation. EMT leads to the generation of mesenchymal cells that will eventually become the inter...
Extravascular activation of the coagulation cascade in the lung is commonly observed in pulmonary fibrosis. Coagulation proteases may exert profibrotic cellular effects via protease-activated receptor...
MUC5B promoter polymorphism and interstitial lung abnormalities.
A common promoter polymorphism (rs35705950) in MUC5B, the gene encoding mucin 5B, is associated with idiopathic pulmonary fibrosis. It is not known whether this polymorphism is associated with interst...
News Articles
MMR booster does not result in worse JIA disease activity in children
Among children with juvenile idiopathic arthritis who had undergone primary immunization, the use of a measles-mumps-rubella booster compared with no booster did not result in worse JIA disease activi...
ImportanceThe immunogenicity and the effects of live attenuated measles-mumps-rubella (MMR) vaccination on disease activity in patients with juvenile idiopathic arthritis (JIA) are matters of concern,...
MMR booster vaccine does not appear to worsen disease activity in children with juvenile arthritis
Among children with juvenile idiopathic arthritis (JIA) who had undergone primary immunization, the use of a measles-mumps-rubella (MMR) booster compared with no booster did not result in worse JIA di...
MMR Booster Safe in Kids with Arthritis (CME/CE)
(MedPage Today) -- The live attenuated booster vaccine for measles, mumps, and rubella (MMR) does not worsen disease in children with juvenile idiopathic arthritis, researchers reported.
NATICK, Mass., June 18, 2013 /PRNewswire/ -- Patients with Parkinson's disease using the Boston Scientific Corporation (NYSE: BSX) Vercise™ DBS (deep brain stimulation) System showed a sign...
TOKYO, June 14, 2013 - Astellas Pharma Inc. (“Astellas”; Tokyo:4503; President and CEO: Yoshihiko Hatanaka) announced today that it has been granted approval in Japan for the additional...
BRISBANE, Calif., June 14, 2013 /PRNewswire/ -- InterMune, Inc. (NASDAQ: ITMN) today announced that the Board of the Italian Drug Agency (AIFA) has approved the pricing and reimbursement conditio...
On June 4, 2013, the Interstitial Cystitis Association, an organization advocating for about 12 million Americans with a painful chronic bladder condition, led a group, including the International Adh...
Tocilizumab Effective In Juvenile Idiopathic Arthritis
A new study presented at EULAR 2013, the Annual Congress of the European League Against Rheumatism shows that tocilizumab is efficacious and leads to a sustained clinically meaningful improvement in c...
Study: Tocilizumab is effective in children with juvenile idiopathic arthritis
A new study presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism shows that tocilizumab is efficacious and leads to a sustained clinically meaningful improvemen...
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Companies
TARIS Biomedical Inc., a specialty pharmaceutical company with deep domain expertise in therapeutics and drug-delivery, is focused on local minimally-invasive drug-device converge...
Cytheris is a privately held clinical-stage biopharmaceutical company focused on research and development of therapies for immune modulation. These drugs aim at reconstituting and enhancing th...
Guided Therapeutics, Inc. (OTCBB: GTHP) is developing a rapid and painless test for the early detection of disease that leads to cervical cancer. The technology is designed...
Clinical Trials
Neurosurgical Use of Interstitial Laser Therapy (ILT)
The researchers' specific aims are to test the following hypotheses: Hypothesis 1: A tumor can be completely ablated by ILT with MRI-guidance. Hypothesis 2: The MRI-based 3D temperature...
Botox as a Treatment for Interstitial Cystitis in Women
Patients with interstitial cystitis have been well documented to have pelvic floor muscle tenderness as well as pain on bladder distension. Some investigators have even suggested that pel...
Alleviated Positioning for Small Macular Holes
Rational of the study: There are arguments to think that the closure of macular holes can be obtained without a strict positioning under certain conditions, i.e. hole size ≤ 400 µm, if...
Treatment of Idiopathic Pulmonary Fibrosis With Thalidomide
The goal of this study is to determine whether thalidomide can stop the progression of fibrosis in IPF. The primary objective of this study is to determine the safety, feasibility and eff...
Enterra Therapy Clinical Study (Gastric Stimulation for Gastroparesis)
This study is to evaluate the safety and effectiveness of gastric stimulation in the reduction of nausea and vomiting in patients with gastroparesis using an approved Humanitarian device....
The primary objective is to assess sustained efficacy in patients who have responded to a 6 month treatment with open-label pramipexole. Secondary objectives are the measurement of severi...
The purpose of this study is to continue the work from the previous review study and determine the effectiveness of Botox in treating patients with idiopathic clubfoot by comparing outcome...
Laser Therapy of Benign Thyroid Nodules
Nodular goitre is common in the general population and less than 5% of the patients who undergo surgery for solitary thyroid nodules have cancer, in absence of clinical suspicion. Nodu...
Functional Characterization of Parkin + Patients
Parkinson’s disease is one of the most frequent neurodegenerative diseases, and for which the mechanisms remains unknown. Since the implication of susceptibility factors is highly suspec...
EUROPAC-2 - Pain Treatment of Hereditary and Idiopathic Pancreatitis
This is a multi-centre randomised phase III, double blind, placebo controlled, parallel group, outpatient study in patients diagnosed with hereditary pancreatitis and idiopathic chronic pa...
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Medical and Biotech [MESH] Definitions
Leukocyte L1 Antigen Complex
A member of the S-100 protein family that is present at high levels in the blood and interstitial fluid in several infectious, inflammatory, and malignant disorders, including rheumatoid arthritis, inflammatory bowel disease, and cystic fibrosis. It is a complex of a light chain (CALGRANULIN A) and a heavy chain (CALGRANULIN B). L1 binds calcium through an EF-hand motif, and has been shown to possess antimicrobial activity.
Leptospira Interrogans Serovar Canicola
A serovar of the bacterial species LEPTOSPIRA INTERROGANS, whose natural host is DOGS where disease is characterized by GASTROENTERITIS, and INTERSTITIAL NEPHRITIS.
Mycoplasma Ovipneumoniae
A species of gram-negative bacteria originally isolated from the LUNGS; TRACHEA; and NASAL CAVITY of SHEEP. It causes chronic interstitial pneumonia (PNEUMONIA, MYCOPLASMA) in both SHEEP and GOATS.
Pure Autonomic Failure
A degenerative disease of the AUTONOMIC NERVOUS SYSTEM that is characterized by idiopathic ORTHOSTATIC HYPOTENSION and a greatly reduced level of CATECHOLAMINES. No other neurological deficits are present.
Idiopathic Interstitial Pneumonias
A group of interstitial lung diseases with no known etiology. There are several entities with varying patterns of inflammation and fibrosis. They are classified by their distinct clinical-radiological-pathological features and prognosis. They include IDIOPATHIC PULMONARY FIBROSIS; CRYPTOGENIC ORGANIZING PNEUMONIA; and others.
