Idiopathic Pulmonary Fibrosis - Biotech, Pharma and Life Science Channel
PubMed Articles
Application of five prognostic survival scores to primary myelofibrosis in 62 Brazilian patients.
Primary myelofibrosis (PM) is a Philadelphia-negative clonal hematopoietic stem cell disorder characterized by intense reactive changes of bone marrow stroma with collagen fibrosis, osteosclerosis and...
AIM. To review the results of implementing a protocol for following up patients with idiopathic intracranial hypertension (IICH) in a neuro-ophthalmological unit (NOU). PATIENTS AND METHODS. A review...
Is idiopathic recurrent pancreatitis attributed to small stones?
Idiopathic recurrent pancreatitis remains a clinical challenge. Intraductal ultrasonography in the management of idiopathic recurrent pancreatitis may be a new strategy for undetermined causes after i...
Inhaled glycopyrronium bromide (Seebri(®) Breezhaler(®) capsules; NVA237) is a once-daily, long-acting muscarinic receptor antagonist (LAMA) that is approved in several countries, including the EU,...
Chronic thromboembolic pulmonary hypertension (CTEPH) and idiopathic pulmonary hypertension (IPAH) share a similar clinical presentation, and a differential diagnosis requires a thorough workup. Once...
Aortopulmonary collateral flow in cystic fibrosis assessed with phase-contrast MRI.
BACKGROUND: Cystic fibrosis (CF) is a common genetic disease in Caucasians. Chronic pulmonary disease with progressive destruction of the pulmonary parenchyma is two of the major morbidities, but the...
Background: Continuous administration of prostacyclin has improved the survival of patients with pulmonary arterial hypertension (PAH). However, this treatment has some problems, including its short...
Non-invasive assessment of cardiac function in a mouse model of renovascular hypertension.
Hypertension continues to be a significant cause of morbidity and mortality, underscoring the need to better understand its early effects on the myocardium. The aim of this study is to determine the f...
AIM AND OBJECTIVES: To describe and compare nutritional status, pulmonary function, gender and marital status in patients with chronic obstructive pulmonary disease. BACKGROUND: Chronic obstructive pu...
Case Description-A 4-year-old sexually intact male mixed-breed dog was evaluated because of clinical signs of acute-onset pelvic limb ataxia, rapidly progressing to paraplegia with severe spinal hyper...
News Articles
Study: VEGF inhibitor appears to improve glaucoma surgical outcomes
The most common cause of failure after glaucoma surgery is scarring at the surgical site, so researchers are actively looking for ways to minimize or prevent scar formation. Previous work had suggeste...
Neupro reduces PLMS and total NSBP elevations in patients with RLS, study finds
UCB today announced data from a double-blind, placebo-controlled study that found that Neupro (Rotigotine Transdermal System) reduced total nocturnal systolic blood pressure elevations associated with...
Boehringer Ingelheim updates HCPs, patients on COMBIVENT RESPIMAT Inhalation Spray
As part of the company's commitment to chronic obstructive pulmonary disease patients, Boehringer Ingelheim Pharmaceuticals, Inc., a leader in respiratory health, is updating healthcare professionals...
Great Strides: Walk for cystic fibrosis
Walks in nearly every state this weekend will raise funds to fight cystic fibrosis as part of Great Strides, the Cystic Fibrosis Foundation's largest national fundraising event.
Dr. Avi Ishaaya Offers Screening and Assessments for Sleep Apnea in Honor of World Hypertension Day
Between May 17 and May 31, 2013, Dr. Avi Ishaaya will offer free screening and assessment for sleep apnea, an identifiable cause of hypertension. Los Angeles, CA (PRWEB) May 17, 2013 Dr. Avi Ishaaya,...
Disease-relevant proteostasis regulation of cystic fibrosis transmembrane conductance regulator
Additional macitentan (Opsumit) data in pulmonary arterial hypertension presented at ATS
Actelion Pharmaceuticals Ltd / Additional macitentan (Opsumit) data in pulmonary arterial hypertension presented at ATS . Processed and transmitted by Thomson Reuters ONE. The issuer is solely respo...
Bayer submits Japanese application for riociguat
Bayer AG (Xetra:BAYN) submitted a regulatory application in Japan for riociguat to treat chronic thromboembolic pulmonary hypertension (CTEPH). The oral soluble guanylyl cyclase (sGC) stimulator is un...
New study shows UCB's Neupro reduces NSBP in RLS patient
Leading Belgian drugmaker UCB (Euronext Brussels: UCB) today (May 17) announced data from a double-blind, placebo-controlled study that found that Neupro (rotigotine transdermal system) reduced total...
Boehringer Ingelheim transitions to propellant-free Combivent Respimat; names new BMD member
German family-owned drug major Boehringer Ingelheim said today (May 17) that it is updating health care professionals (HCPs) and patients that the transition to Combivent Respimat (ipratropium bromide...
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Companies
Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...
RXi Pharmaceuticals Corporation
RXi Pharmaceuticals Corporation (OTC: RXII) is a biotechnology company focused on discovering, developing and commercializing innovative therapies based on its proprietary, next-generation RNAi plat...
GenMark, a provider of automated, multiplex molecular diagnostic testing systems, detects and measures DNA and RNA targets to diagnose disease and to optimize the treatment of pat...
Xcovery Vision is an ophthalmology-focused subsidiary of Xcovery Holding, a clinical-stage company developing novel therapies for cancer and inflammatory diseases. Xcovery Vision'...
Electromed, Inc., founded in 1992 and headquartered in New Prague, Minnesota, manufactures, markets and sells products that provide airway clearance therapy, including the SmartVe...
New Lung Associates is a pulmonary group of physicians leading the Lung Transplant Program and the Adult Cystic Fibrosis Program at Tampa General Hospital, a 988-bed acute care ho...
Pulmonary Hypertension Association (PHA)
Headquartered in Silver Spring, Md., PHA is the countryâs leading organization connecting pulmonary hypertension patients, families, and medical professionals. Its mission is...
Activaero is the world leader in the design of controlled breathing drug delivery technologies that maximize the efficiency and precision of inhaled drugs. These innovative techno...
Pulse Health was established in 2006 to deliver breakthrough breath technologies that can better identify health risks through the superior measurement of key biomarkers. Pulse He...
Headquartered in Montvale, NJ, PENTAX Medical Company is a division of PENTAX of America, Inc., a consolidated subsidiary of HOYA Corporation. PENTAX Medical Company is an industr...
Clinical Trials
The purpose of this study is to demonstrate the safety and effectiveness of the CardioFocus Endoscopic Ablation System with Adaptive Contact (HeartLight) in the treatment of atrial fibrill...
Prospective, single center, descriptive study in 14 infants/children with multivessel pulmonary vein stenosis stratified for patients with or without underlying cardiac disease. Group 1:...
Vinblastine and Methotrexate in Children With Pulmonary Vein Stenosis
To evaluate the efficacy of the chemotherapeutic agents vinblastine and methotrexate in the treatment of two groups of children with multivessel pulmonary vein stenosis. Group 1 will cont...
Study Protocol Evaluating Transient Tachypnoea of the Newborn in Term and Near Term Neonates
Transient tachypnoea of the newborn (TTN) is a common cause of hospitalisation in the neonatal period, complicating 1 to 1,5 per cent life birth. Predisposing factors are prematurity, birt...
Exhale (R) Stent for Emphysema
Current treatment for emphysema is limited to measures that include inhaled oxygen, bronchodilators, anti-inflammatory drugs and pulmonary rehabilitation. Highly invasive procedures such...
Pilot Studies of Novel Therapies to Treat Resistant Focal Segmental Glomerulosclerosis (FSGS)
The current management of primary FSGS is predicated on the assumption that the disease is caused by an immune-mediated disturbance in glomerular barrier function. Therefore, most treatmen...
Alleviated Positioning for Small Macular Holes
Rational of the study: There are arguments to think that the closure of macular holes can be obtained without a strict positioning under certain conditions, i.e. hole size ≤ 400 µm, if...
Strategies for Suspected Pulmonary Embolism in Emergency Departments
Aims: 1) To evaluate the effectiveness of two interventions aimed at improving the management of patients with suspected pulmonary embolism: Written guidelines and Computer-Assisted Decisi...
Blood clots in the leg veins, known as deep vein thrombosis, are important because they may travel to the lung (known as pulmonary embolism) and cause death. Blood clots are treated with...
Selenium Supplementation in Chronic Obstructive Pulmonary Disease (COPD) Patients
Does an oral selenium supplement increase blood levels of antioxidants in patients with established, smoking-related lung disease? Members of our study group recently discovered that elev...
Videos
Idiopathic Pulmonary Fibrosis
The surgery will be hosted by Helen Parfrey, a Consultant Respiratory Physician at Papworth Hospital and an interstitial lung disease expert. The surgery tal...
Medical and Biotech [MESH] Definitions
Pulmonary Surfactant-associated Proteins
Proteins found in the LUNG that act as PULMONARY SURFACTANTS.
Pulmonary Surfactant-associated Protein A
An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.
Pulmonary Surfactant-associated Protein D
An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens and enhances their opsinization and killing by phagocytic cells. Surfactant protein D contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.
Pulmonary Surfactant-associated Protein B
A pulmonary surfactant associated-protein that plays an essential role in alveolar stability by lowering the surface tension at the air-liquid interface. Inherited deficiency of pulmonary surfactant-associated protein B is one cause of RESPIRATORY DISTRESS SYNDROME, NEWBORN.
Pulmonary Surfactant-associated Protein C
A pulmonary surfactant associated protein that plays a role in alveolar stability by lowering the surface tension at the air-liquid interface. It is a membrane-bound protein that constitutes 1-2% of the pulmonary surfactant mass. Pulmonary surfactant-associated protein C is one of the most hydrophobic peptides yet isolated and contains an alpha-helical domain with a central poly-valine segment that binds to phospholipid bilayers.
