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Imaging studies - Biotech, Pharma and Life Science Channel

04:40 EDT 22nd May 2013 | BioPortfolio

PubMed Articles [ 9168 Associated PubMed Articles listed on BioPortfolio]

Towards real-time VMAT verification using a prototype, high-speed CMOS active pixel sensor.

This work investigates the feasibility of using a prototype complementary metal oxide semiconductor active pixel sensor (CMOS APS) for real-time verification of volumetric modulated arc therapy (VMAT)...

Simulation-based reconstruction of absolute activities from the (99m)Tc/(111)In dual-isotope SPECT/CT: phantom experiments and imaging of neuroendocrine tumors.

We investigate the quantitative accuracy of the reconstruction of absolute (99m)Tc and (111)In activities from (99m)Tc/(111)In dual-isotope SPECT studies. The separate reconstruction of two images is...

Total synthesis and structure-activity relationship study of the potent cAMP signaling agonist (-)-alotaketal A.

A detailed account of the first total synthesis of alotaketal A, a tricyclic spiroketal sesterterpenoid that potently activates the cAMP signaling pathway, is provided. The synthesis employs both intr...

Imaging mRNA expression levels in living cells with PNA·DNA binary FRET probes delivered by cationic shell-crosslinked nanoparticles.

Optical imaging of gene expression through the use of fluorescent antisense probes targeted to the mRNA has been an area of great interest. The main obstacles to developing highly sensitive antisense...

Facile synthesis of magnetite/perfluorocarbon co-loaded organic/inorganic hybrid vesicles for dual-modality ultrasound/magnetic resonance imaging and imaging-guided high-intensity focused ultrasound ablation.

Multifunctional organic/inorganic hybrid nanovesicles, fabricated by a facile self-assembly/sol-gel approach, display a unique morphology (figure) and satisfactory stability under physiological condit...

NanoSIMS multi-element imaging reveals internalisation and nucleolar targeting for a highly-charged polynuclear platinum compound.

Simultaneous multi-element imaging using NanoSIMS (nano-scale secondary ion mass spectrometry), exploiting the novel combination of (195)Pt and (15)N in platinum-am(m)ine antitumour drugs, provides in...

Sensitive and high resolution subcutaneous fluorescence in vivo imaging using upconversion nanoparticles and microarrays.

A sensitive and high resolution small animal in vivo imaging system using upconversion nanoparticles (UNPs) and microarrays was developed. The fluorescence tomography using UNPs could achieve higher p...

Radionuclide parathyroid imaging: a concise, updated review.

The hypercalcemia of hyperparathyroidism (HPT) can cause devastating effects to the patient and only surgical removal of the hyperfunctioning parathyroid tissue can definitely cure the disease. Radion...

Functional and structural brain changes in anti-NMDAR encephalitis.

OBJECTIVE: Anti-NMDA receptor (NMDAR) encephalitis is an autoimmune encephalitis with a characteristic neuropsychiatric syndrome and severe and prolonged clinical courses. In contrast, standard clinic...

A squaraine-based red emission off-on chemosensor for biothiols and its application in living cells imaging.

A new probe based on the squaraine skeleton with a 2,4-dinitrobenzenesulfonyl unit is reported as a fluorescent probe for biothiol. It shows turn-on properties with red emission towards biothiols in a...

News Articles [ 7109 Associated News Articles listed on BioPortfolio]

Industry Leading Test Laboratory, BioScience Laboratories, Inc. Concludes Phase 1 Safety Evaluations in 12 Weeks, Exceeds Market Value, and Timeline, Again

BioScience Laboratories, Inc. Clinical Laboratory has again exceeded market standards for Phase 1 Dermatological Safety Studies for an IND submission. Phase I Dermatological Safety Studies represent a...

New York University Acquires 100th Leica Confocal Laser Scanning Microscope with White Light Laser for Morphogenetic Studies

The Leica TCS SP8 X provides total freedom of excitation and emission coupled with low laser power and high sensitivity The Department of Biology at New York University has been equipped with the 100t...

Elbit Imaging Announces the Court Decision with Respect to Filing of Plan of Arrangement with the Israeli Court

TEL AVIV, Israel, May 22, 2013 /PRNewswire/ -- Elbit Imaging Ltd. ("EI" or the "Company") (TASE, NASDAQ: EMITF) announced today, further to the Company's announcement dated May 9, 2013 that it had fi...

Studies show that LipiGesic M provides highly effective OTC solution to migraine pain

PuraMed BioScience, Inc., a researcher, developer, and marketer of over-the-counter medicinal and healthcare products, announced the results of clinical trials that found its over-the-counter migraine...

CT radiation risks coming into clearer focus

Recent attention to the cancer risks of ionizing radiation has prompted vigorous debate about how to quantify the risks of diagnostic imaging, and whether or how these risks ought to be incorporated.....

Sudden Purpuriform Rash in an Infant Sudden Purpuriform Rash in an Infant

A 10-month-old boy presents with erythematous swelling of bothears and right eyelid and erythematous perioral macules following a respiratory tract infection 12 days before presentation (Figure, A). W...

Musculoskeletal ultrasonography in patients with rheumatoid arthritis

Musculoskeletal ultrasonography is widely used for evaluating patients with RA and these imaging techniques can also allow the comparison of therapeutic agents, as well as monitoring patient response...

Parker Waichman LLP Comments on New Study Showing that MRI is Useful for Predicting Failure of Metal-on-Metal Hip Implants

A new study published in the Journal of Bone & Joint Surgery shows that magnetic resonance imaging (MRI) can help detect failure of metal-on-metal hip implants even before symptoms appear. Parker...

Noninvasive identification and assessment of functional brown adipose tissue in rodents using hyperpolarized 13C imaging

Diagnosis: Biomarkers of cardiovascular outcomes—bonanza or bias?

During the past decade, a plethora of biomarkers have been reported to be associated with incident cardiovascular disease, often in large meta-analyses. A new review of these meta-analyses suggests th...

Events [ 2 Associated Events listed on BioPortfolio]

Diabetes: Secondary Complications, Regulation and Innovation Conference

SMi is very proud to present our 11th conference focusing on Diabetes and metabolic disorders taking place on 1st and 2nd Oct 2013, London.

2nd Annual Oncology Clinical Development Congress 2013

2 day conference covering clinical development best practice and clinical trial management

Companies [ 296 Associated Companies listed on BioPortfolio]

Auxogyn, Inc.

Auxogyn is a privately held medical technology company focused on advancing women's reproductive health by applying its novel scientific and clinical knowledge of early human developmental biology to...

Circadian Technologies Limited

Circadian Technologies Limited is an emerging leader in the field of angiogenesis-based treatments for cancer. Focusing on a class of drug targets called Vascular Endothelial Growth Factors (VEGFs),...

PatientsLikeMe

PatientsLikeMe is a patient network that improves lives and a real-time research platform that advances medicine. Through the network, patients connect with others who have the sa...

Fry Construction, Inc.

Fry Construction Company, Inc., is a leader in the precision construction of medical facilities. Since completing Dallas’ first magnetic resonance imaging center in 1984, Fry...

Hoya Corporation

Hoya Corporation is a global technology company based in Tokyo, Japan, and the leading supplier of innovative and indispensable high-tech products and services based upon its advanced optics techn...

Siemens Healthcare

The Siemens Healthcare Sector is one of the world's largest suppliers to the healthcare industry and a trendsetter in medical imaging, laboratory diagnostics, medical information...

DR Systems, Inc.

DR Systems, Inc. is the leading independent provider of enterprise imaging and information management systems for hospitals, integrated healthcare networks and diagnostic imaging...

Diversified Information Technologies Inc.

Diversified Information Technologies Inc., founded in 1982, is headquartered in Scranton, Pa. Diversified’s solutions manage the complete document and information lifecycle a...

Spaulding Clinical

Spaulding Clinical (www.spauldingclinical.com) is a Phase 1 Clinical Pharmacology Research Unit and Electrocardiography Core Lab located in West Bend, Wisconsin offering a full ra...

Lantos Technologies, Inc.

Lantos Technologies is developing the world’s first intra-aural 3D scanner, which has applications across multiple consumer markets. Lantos’ novel 3D imaging technology...

Clinical Trials [ 1614 Associated Clinical Trials listed on BioPortfolio]

Positron Emission Tomography (PET) to Study Brain Signaling

This study uses positron emission tomography (PET) to examine brain function and signaling involving phospholipids, and to see how signaling is related to blood flow. Much of the brain is...

89Zr-trastuzumab PET for Imaging the Effect of HSP90 Inhibition

HSP90 inhibition is a potentially new targeted drug modality in the treatment of HER2 positive, trastuzumab refractory breast cancer. Little is known about the pharmacodynamics of HSP90 in...

Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression

Background: - Atherosclerosis (thickening of the artery walls caused by cholesterol and other deposits) commonly occurs in the heart vessels and carotid (neck) arteries of adults. This i...

Usefulness of Myocardial Deformation Imaging for Trastuzumab-induced Cardiotoxicity

Trastuzumab prolongs survival in patients with human epidermal growth factor receptor type 2-positive breast cancer. Sequential left ventricular (LV) ejection fraction (EF) assessment has...

Exploration of Tumor Accumulation of BAY94-9392 in Patients With Cancer

The study will be conducted as an open label, single-dose, explorative study with patients with histologically proven cancer and, preferably, tumor positive lesions in previously performed...

Clonidine and Left Ventricular Dysfunction

The objectives of this study are: 1. To evaluate the effect of clonidine, a sympathetic modulator, to reverse cardiac remodeling and to improve hemodynamics in diastolic heart fail...

Evaluation of Myocardial Viability by Means of Low-Dose Dobutamine Gated SPECT (the DOGS Study)

Viability assessment remains a clinical challenge in patient with coronary artery disease and left ventricular dysfunction. Several imaging modalities are available for evaluating myocardi...

Resynchronization Therapy in Young Patients With and Without CHD

Pacemakers can be attached to one or more than one of the heart chambers. After watching pacemakers work over time, doctors have found that the pacemakers that stimulate only one chamber o...

ADVANCE MPI 2: Study of Regadenoson Versus Adenoscan® in Patients Undergoing Myocardial Perfusion Imaging (MPI)

Adenoscan® (adenosine) is an approved pharmacological stress agent indicated as an adjunct to thallium-201 myocardial perfusion scintigraphy in patients unable to exercise adequately. Th...

Airway Inflammation in Swimmers

Studies have shown that the prevalence of respiratory symptoms, airway hyperresponsiveness (AHR) and asthma is high and increasing in elite athletes. The inflammation seen in the airways o...

Medical and Biotech [MESH] Definitions

Nontherapeutic Human Experimentation

Human experimentation that is not intended to benefit the subjects on whom it is performed. Phase I drug studies (CLINICAL TRIALS, PHASE I AS TOPIC) and research involving healthy volunteers are examples of nontherapeutic human experimentation.

Control Groups

Groups that serve as a standard for comparison in experimental studies. They are similar in relevant characteristics to the experimental group but do not receive the experimental intervention.

Research Subjects

Persons who are enrolled in research studies or who are otherwise the subjects of research.

Microscopy, Fluorescence, Multiphoton

Fluorescence microscopy utilizing multiple low-energy photons to produce the excitation event of the fluorophore. Multiphoton microscopes have a simplified optical path in the emission side due to the lack of an emission pinhole, which is necessary with normal confocal microscopes. Ultimately this allows spatial isolation of the excitation event, enabling deeper imaging into optically thick tissue, while restricting photobleaching and phototoxicity to the area being imaged.

Flaveria

A plant genus of the family ASTERACEAE that is used for experiments in molecular genetic studies in plant physiology and development.

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