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Imaging studies - Biotech, Pharma and Life Science Channel

05:03 EDT 23rd May 2013 | BioPortfolio

PubMed Articles [ 9183 Associated PubMed Articles listed on BioPortfolio]

Towards real-time VMAT verification using a prototype, high-speed CMOS active pixel sensor.

This work investigates the feasibility of using a prototype complementary metal oxide semiconductor active pixel sensor (CMOS APS) for real-time verification of volumetric modulated arc therapy (VMAT)...

Simulation-based reconstruction of absolute activities from the (99m)Tc/(111)In dual-isotope SPECT/CT: phantom experiments and imaging of neuroendocrine tumors.

We investigate the quantitative accuracy of the reconstruction of absolute (99m)Tc and (111)In activities from (99m)Tc/(111)In dual-isotope SPECT studies. The separate reconstruction of two images is...

Total synthesis and structure-activity relationship study of the potent cAMP signaling agonist (-)-alotaketal A.

A detailed account of the first total synthesis of alotaketal A, a tricyclic spiroketal sesterterpenoid that potently activates the cAMP signaling pathway, is provided. The synthesis employs both intr...

Imaging mRNA expression levels in living cells with PNA·DNA binary FRET probes delivered by cationic shell-crosslinked nanoparticles.

Optical imaging of gene expression through the use of fluorescent antisense probes targeted to the mRNA has been an area of great interest. The main obstacles to developing highly sensitive antisense...

Facile synthesis of magnetite/perfluorocarbon co-loaded organic/inorganic hybrid vesicles for dual-modality ultrasound/magnetic resonance imaging and imaging-guided high-intensity focused ultrasound ablation.

Multifunctional organic/inorganic hybrid nanovesicles, fabricated by a facile self-assembly/sol-gel approach, display a unique morphology (figure) and satisfactory stability under physiological condit...

Posterior cortical atrophy and Alzheimer's disease: a meta-analytic review of neuropsychological and brain morphometry studies.

This paper presents the first systematic review and meta-analysis of neuropsychological and brain morphometry studies comparing posterior cortical atrophy (PCA) to typical Alzheimer's disease (tAD). L...

Serum amyloid A-positive hepatocellular neoplasms in the resected livers from 3 patients with alcoholic cirrhosis.

Twelve hepatocellular nodules were characterized in the resected livers from 3 patients (2 men and a woman) with alcoholic cirrhosis. Imaging techniques suggested that the nodules were hypervascular a...

Erratum to: Comparison of (18)F-labeled CXCR4 antagonist peptides for PET imaging of CXCR4 expression.

Development of an Oxygen-Sensitive Degradable Peptide Probe for the Imaging of Hypoxia-Inducible Factor-1-Active Regions in Tumors.

PURPOSE: We aimed to develop a radiolabeled peptide probe for the imaging of hypoxia-inducible factor-1 (HIF-1)-active tumors. PROCEDURES: We synthesized the peptide probes that contain or lack an ess...

In Vitro and In Vivo Evaluation of the Caspase-3 Substrate-Based Radiotracer (18)F-CP18 for PET Imaging of Apoptosis in Tumors.

PURPOSE: A novel caspase-3 substrate-based probe [(18)F]-CP18 was evaluated as an in vivo positron emission tomography (PET) imaging agent for monitoring apoptosis in tumors. METHODS: Uptake of [(18)F...

News Articles [ 7097 Associated News Articles listed on BioPortfolio]

Intermountain Healthcare Launches Nation’s First System to Measure and Report Cumulative Medical Radiation Exposure

In recent years, new medical knowledge has raised concerns about the safety of radiation used in some medical diagnostic imaging tests. But until now, a program to accurately meas...

Random forest fishing: a novel approach to identifying organic group of risk factors in genome-wide association studies

A modified two-stage approach for family-based genome-wide association studies

The big fat truth

More and more studies show that being overweight does not always shorten life — but some public-health researchers would rather not talk about them.

Deprivation: A wake-up call

Studies that restrict sleep show why a lack of shut-eye can lead to serious chronic disease.

Development: Images of a metamorphosis

A three-dimensional imaging technique makes it possible to watch butterfly pupae mature within the chrysalis.In most studies of developing insects, seeing means destroying. Researchers must dissect a...

More Evidence Fecal Transplant Clears C. Diff (CME/CE)

ORLANDO (MedPage Today) -- Fecal transplant for Clostridium difficile infection is a safe and effective treatment and can alter patients' fecal microbiota to resemble that of donors over time, studies...

Cognoptix Test Identifies Alzheimer’s Disease via Beta Amyloid Signature in the Eyes in Proof-of-Concept Clinical Trial

Data, published in Frontiers in Neurology, will be presented at the Alzheimer’s Association International Conference (AAIC) in Boston “This simple eye test has the po...

EOS imaging Announces Sales Force Structure in Asia

New Distribution Agreements and Regional Office Pave Way for Further Commercialization of EOS® 3D Imaging System EOS imaging (NYSE Euronext, FR0011191766 – EOSI), the pione...

IMRIS Announces US Patent for Microsurgical Robot Concept

Key patent includes claims on haptics, MR compatibility and image-guidance WINNIPEG, May 22, 2013 /PRNewswire/ - IMRIS Inc. (NASDAQ: IMRS; TSX: IM) ("IMRIS" or the "Company") today announced the...

Events [ 2 Associated Events listed on BioPortfolio]

Diabetes: Secondary Complications, Regulation and Innovation Conference

SMi is very proud to present our 11th conference focusing on Diabetes and metabolic disorders taking place on 1st and 2nd Oct 2013, London.

2nd Annual Oncology Clinical Development Congress 2013

2 day conference covering clinical development best practice and clinical trial management

Companies [ 297 Associated Companies listed on BioPortfolio]

THE Surgical Hospital of Phoenix

THE Surgical Hospital of Phoenix, the first licensed surgical specialty facility of its kind in Arizona, first opened its doors in May of 2005. Specializing in spine, orthopedics,...

TetraLogic Pharmaceuticals

TetraLogic Pharmaceuticals is a privately held biopharmaceutical company that discovers and develops small molecule drugs that modulate programmed cell death pathways to treat deb...

Auxogyn, Inc.

Auxogyn – Advancing women’s reproductive health through novel scientific and clinical knowledge of early human developmental biology auxology (from Greek αὔξω, auxō,...

Circadian Technologies Limited

Circadian Technologies Limited is an emerging leader in the field of angiogenesis-based treatments for cancer. Focusing on a class of drug targets called Vascular Endothelial Growth Factors (VEGFs),...

PatientsLikeMe

PatientsLikeMe is a patient network that improves lives and a real-time research platform that advances medicine. Through the network, patients connect with others who have the sa...

Fry Construction, Inc.

Fry Construction Company, Inc., is a leader in the precision construction of medical facilities. Since completing Dallas’ first magnetic resonance imaging center in 1984, Fry...

Hoya Corporation

Hoya Corporation is a global technology company based in Tokyo, Japan, and the leading supplier of innovative and indispensable high-tech products and services based upon its advanced optics techn...

Siemens Healthcare

The Siemens Healthcare Sector is one of the world's largest suppliers to the healthcare industry and a trendsetter in medical imaging, laboratory diagnostics, medical information...

DR Systems, Inc.

DR Systems, Inc. is the leading independent provider of enterprise imaging and information management systems for hospitals, integrated healthcare networks and diagnostic imaging...

Diversified Information Technologies Inc.

Diversified Information Technologies Inc., founded in 1982, is headquartered in Scranton, Pa. Diversified’s solutions manage the complete document and information lifecycle a...

Clinical Trials [ 1614 Associated Clinical Trials listed on BioPortfolio]

Positron Emission Tomography (PET) to Study Brain Signaling

This study uses positron emission tomography (PET) to examine brain function and signaling involving phospholipids, and to see how signaling is related to blood flow. Much of the brain is...

89Zr-trastuzumab PET for Imaging the Effect of HSP90 Inhibition

HSP90 inhibition is a potentially new targeted drug modality in the treatment of HER2 positive, trastuzumab refractory breast cancer. Little is known about the pharmacodynamics of HSP90 in...

Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression

Background: - Atherosclerosis (thickening of the artery walls caused by cholesterol and other deposits) commonly occurs in the heart vessels and carotid (neck) arteries of adults. This i...

Usefulness of Myocardial Deformation Imaging for Trastuzumab-induced Cardiotoxicity

Trastuzumab prolongs survival in patients with human epidermal growth factor receptor type 2-positive breast cancer. Sequential left ventricular (LV) ejection fraction (EF) assessment has...

Exploration of Tumor Accumulation of BAY94-9392 in Patients With Cancer

The study will be conducted as an open label, single-dose, explorative study with patients with histologically proven cancer and, preferably, tumor positive lesions in previously performed...

Clonidine and Left Ventricular Dysfunction

The objectives of this study are: 1. To evaluate the effect of clonidine, a sympathetic modulator, to reverse cardiac remodeling and to improve hemodynamics in diastolic heart fail...

Evaluation of Myocardial Viability by Means of Low-Dose Dobutamine Gated SPECT (the DOGS Study)

Viability assessment remains a clinical challenge in patient with coronary artery disease and left ventricular dysfunction. Several imaging modalities are available for evaluating myocardi...

Resynchronization Therapy in Young Patients With and Without CHD

Pacemakers can be attached to one or more than one of the heart chambers. After watching pacemakers work over time, doctors have found that the pacemakers that stimulate only one chamber o...

ADVANCE MPI 2: Study of Regadenoson Versus Adenoscan® in Patients Undergoing Myocardial Perfusion Imaging (MPI)

Adenoscan® (adenosine) is an approved pharmacological stress agent indicated as an adjunct to thallium-201 myocardial perfusion scintigraphy in patients unable to exercise adequately. Th...

Airway Inflammation in Swimmers

Studies have shown that the prevalence of respiratory symptoms, airway hyperresponsiveness (AHR) and asthma is high and increasing in elite athletes. The inflammation seen in the airways o...

Medical and Biotech [MESH] Definitions

Nontherapeutic Human Experimentation

Human experimentation that is not intended to benefit the subjects on whom it is performed. Phase I drug studies (CLINICAL TRIALS, PHASE I AS TOPIC) and research involving healthy volunteers are examples of nontherapeutic human experimentation.

Control Groups

Groups that serve as a standard for comparison in experimental studies. They are similar in relevant characteristics to the experimental group but do not receive the experimental intervention.

Research Subjects

Persons who are enrolled in research studies or who are otherwise the subjects of research.

Microscopy, Fluorescence, Multiphoton

Fluorescence microscopy utilizing multiple low-energy photons to produce the excitation event of the fluorophore. Multiphoton microscopes have a simplified optical path in the emission side due to the lack of an emission pinhole, which is necessary with normal confocal microscopes. Ultimately this allows spatial isolation of the excitation event, enabling deeper imaging into optically thick tissue, while restricting photobleaching and phototoxicity to the area being imaged.

Flaveria

A plant genus of the family ASTERACEAE that is used for experiments in molecular genetic studies in plant physiology and development.

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