Imaging studies - Biotech, Pharma and Life Science Channel
PubMed Articles
Towards real-time VMAT verification using a prototype, high-speed CMOS active pixel sensor.
This work investigates the feasibility of using a prototype complementary metal oxide semiconductor active pixel sensor (CMOS APS) for real-time verification of volumetric modulated arc therapy (VMAT)...
We investigate the quantitative accuracy of the reconstruction of absolute (99m)Tc and (111)In activities from (99m)Tc/(111)In dual-isotope SPECT studies. The separate reconstruction of two images is...
A detailed account of the first total synthesis of alotaketal A, a tricyclic spiroketal sesterterpenoid that potently activates the cAMP signaling pathway, is provided. The synthesis employs both intr...
Optical imaging of gene expression through the use of fluorescent antisense probes targeted to the mRNA has been an area of great interest. The main obstacles to developing highly sensitive antisense...
Multifunctional organic/inorganic hybrid nanovesicles, fabricated by a facile self-assembly/sol-gel approach, display a unique morphology (figure) and satisfactory stability under physiological condit...
Simultaneous multi-element imaging using NanoSIMS (nano-scale secondary ion mass spectrometry), exploiting the novel combination of (195)Pt and (15)N in platinum-am(m)ine antitumour drugs, provides in...
A sensitive and high resolution small animal in vivo imaging system using upconversion nanoparticles (UNPs) and microarrays was developed. The fluorescence tomography using UNPs could achieve higher p...
Radionuclide parathyroid imaging: a concise, updated review.
The hypercalcemia of hyperparathyroidism (HPT) can cause devastating effects to the patient and only surgical removal of the hyperfunctioning parathyroid tissue can definitely cure the disease. Radion...
Functional and structural brain changes in anti-NMDAR encephalitis.
OBJECTIVE: Anti-NMDA receptor (NMDAR) encephalitis is an autoimmune encephalitis with a characteristic neuropsychiatric syndrome and severe and prolonged clinical courses. In contrast, standard clinic...
A new probe based on the squaraine skeleton with a 2,4-dinitrobenzenesulfonyl unit is reported as a fluorescent probe for biothiol. It shows turn-on properties with red emission towards biothiols in a...
News Articles
BioScience Laboratories, Inc. Clinical Laboratory has again exceeded market standards for Phase 1 Dermatological Safety Studies for an IND submission. Phase I Dermatological Safety Studies represent a...
The Leica TCS SP8 X provides total freedom of excitation and emission coupled with low laser power and high sensitivity The Department of Biology at New York University has been equipped with the 100t...
TEL AVIV, Israel, May 22, 2013 /PRNewswire/ -- Elbit Imaging Ltd. ("EI" or the "Company") (TASE, NASDAQ: EMITF) announced today, further to the Company's announcement dated May 9, 2013 that it had fi...
Studies show that LipiGesic M provides highly effective OTC solution to migraine pain
PuraMed BioScience, Inc., a researcher, developer, and marketer of over-the-counter medicinal and healthcare products, announced the results of clinical trials that found its over-the-counter migraine...
CT radiation risks coming into clearer focus
Recent attention to the cancer risks of ionizing radiation has prompted vigorous debate about how to quantify the risks of diagnostic imaging, and whether or how these risks ought to be incorporated.....
Sudden Purpuriform Rash in an Infant Sudden Purpuriform Rash in an Infant
A 10-month-old boy presents with erythematous swelling of bothears and right eyelid and erythematous perioral macules following a respiratory tract infection 12 days before presentation (Figure, A). W...
Musculoskeletal ultrasonography in patients with rheumatoid arthritis
Musculoskeletal ultrasonography is widely used for evaluating patients with RA and these imaging techniques can also allow the comparison of therapeutic agents, as well as monitoring patient response...
A new study published in the Journal of Bone & Joint Surgery shows that magnetic resonance imaging (MRI) can help detect failure of metal-on-metal hip implants even before symptoms appear. Parker...
Diagnosis: Biomarkers of cardiovascular outcomes—bonanza or bias?
During the past decade, a plethora of biomarkers have been reported to be associated with incident cardiovascular disease, often in large meta-analyses. A new review of these meta-analyses suggests th...
Events
Diabetes: Secondary Complications, Regulation and Innovation Conference
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2nd Annual Oncology Clinical Development Congress 2013
2 day conference covering clinical development best practice and clinical trial management
Companies
Auxogyn is a privately held medical technology company focused on advancing women's reproductive health by applying its novel scientific and clinical knowledge of early human developmental biology to...
Circadian Technologies Limited
Circadian Technologies Limited is an emerging leader in the field of angiogenesis-based treatments for cancer. Focusing on a class of drug targets called Vascular Endothelial Growth Factors (VEGFs),...
PatientsLikeMe is a patient network that improves lives and a real-time research platform that advances medicine. Through the network, patients connect with others who have the sa...
Fry Construction Company, Inc., is a leader in the precision construction of medical facilities. Since completing Dallasâ first magnetic resonance imaging center in 1984, Fry...
Hoya Corporation is a global technology company based in Tokyo, Japan, and the leading supplier of innovative and indispensable high-tech products and services based upon its advanced optics techn...
The Siemens Healthcare Sector is one of the world's largest suppliers to the healthcare industry and a trendsetter in medical imaging, laboratory diagnostics, medical information...
DR Systems, Inc. is the leading independent provider of enterprise imaging and information management systems for hospitals, integrated healthcare networks and diagnostic imaging...
Diversified Information Technologies Inc.
Diversified Information Technologies Inc., founded in 1982, is headquartered in Scranton, Pa. Diversifiedâs solutions manage the complete document and information lifecycle a...
Spaulding Clinical (www.spauldingclinical.com) is a Phase 1 Clinical Pharmacology Research Unit and Electrocardiography Core Lab located in West Bend, Wisconsin offering a full ra...
Lantos Technologies is developing the worldâs first intra-aural 3D scanner, which has applications across multiple consumer markets. Lantosâ novel 3D imaging technology...
Clinical Trials
Positron Emission Tomography (PET) to Study Brain Signaling
This study uses positron emission tomography (PET) to examine brain function and signaling involving phospholipids, and to see how signaling is related to blood flow. Much of the brain is...
89Zr-trastuzumab PET for Imaging the Effect of HSP90 Inhibition
HSP90 inhibition is a potentially new targeted drug modality in the treatment of HER2 positive, trastuzumab refractory breast cancer. Little is known about the pharmacodynamics of HSP90 in...
Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression
Background: - Atherosclerosis (thickening of the artery walls caused by cholesterol and other deposits) commonly occurs in the heart vessels and carotid (neck) arteries of adults. This i...
Usefulness of Myocardial Deformation Imaging for Trastuzumab-induced Cardiotoxicity
Trastuzumab prolongs survival in patients with human epidermal growth factor receptor type 2-positive breast cancer. Sequential left ventricular (LV) ejection fraction (EF) assessment has...
Exploration of Tumor Accumulation of BAY94-9392 in Patients With Cancer
The study will be conducted as an open label, single-dose, explorative study with patients with histologically proven cancer and, preferably, tumor positive lesions in previously performed...
Clonidine and Left Ventricular Dysfunction
The objectives of this study are: 1. To evaluate the effect of clonidine, a sympathetic modulator, to reverse cardiac remodeling and to improve hemodynamics in diastolic heart fail...
Evaluation of Myocardial Viability by Means of Low-Dose Dobutamine Gated SPECT (the DOGS Study)
Viability assessment remains a clinical challenge in patient with coronary artery disease and left ventricular dysfunction. Several imaging modalities are available for evaluating myocardi...
Resynchronization Therapy in Young Patients With and Without CHD
Pacemakers can be attached to one or more than one of the heart chambers. After watching pacemakers work over time, doctors have found that the pacemakers that stimulate only one chamber o...
Adenoscan® (adenosine) is an approved pharmacological stress agent indicated as an adjunct to thallium-201 myocardial perfusion scintigraphy in patients unable to exercise adequately. Th...
Airway Inflammation in Swimmers
Studies have shown that the prevalence of respiratory symptoms, airway hyperresponsiveness (AHR) and asthma is high and increasing in elite athletes. The inflammation seen in the airways o...
Videos
Medical and Biotech [MESH] Definitions
Nontherapeutic Human Experimentation
Human experimentation that is not intended to benefit the subjects on whom it is performed. Phase I drug studies (CLINICAL TRIALS, PHASE I AS TOPIC) and research involving healthy volunteers are examples of nontherapeutic human experimentation.
Control Groups
Groups that serve as a standard for comparison in experimental studies. They are similar in relevant characteristics to the experimental group but do not receive the experimental intervention.
Research Subjects
Persons who are enrolled in research studies or who are otherwise the subjects of research.
Microscopy, Fluorescence, Multiphoton
Fluorescence microscopy utilizing multiple low-energy photons to produce the excitation event of the fluorophore. Multiphoton microscopes have a simplified optical path in the emission side due to the lack of an emission pinhole, which is necessary with normal confocal microscopes. Ultimately this allows spatial isolation of the excitation event, enabling deeper imaging into optically thick tissue, while restricting photobleaching and phototoxicity to the area being imaged.
Flaveria
A plant genus of the family ASTERACEAE that is used for experiments in molecular genetic studies in plant physiology and development.
