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Insulin rDNA inhaled Pfizer - Biotech, Pharma and Life Science Channel

22:32 EDT 22nd May 2013 | BioPortfolio

PubMed Articles [ 5083 Associated PubMed Articles listed on BioPortfolio]

New data on Longidorus aetnaeus Roca, Lamberti, Agostinelli & Vinciguerra, 1986 (Nematoda: Longidoridae) from Iran and Ajaria (Georgia).

Longidorus aetnaeus Roca, Lamberti, Agostinelli & Vinciguerra, 1986 is reported for the first time from Iran and Ajaria (Georgia). Morphological and morphometric data are provided for two Iranian and...

Morphological and molecular characterisation of Xiphinema macroacanthum Lamberti, Roca & Agostinelli, 1989 (Nematoda: Longidoridae) from olive orchards in southern Italy.

A population of Xiphinema macroacanthum Lamberti, Roca & Agostinelli, 1989 originating from olive orchards in Brindisi, Italy and containing both adults and all juvenile stages, is described and illus...

Fingerprint signatures of lanthanide circularly polarized luminescence from proteins covalently labeled with a β-diketonate europium(iii) chelate.

Fingerprint signatures of circularly polarized luminescence (CPL) are observed from Staphylococcus aureus nuclease (SNase), bovine serum albumin (BSA), and insulin (Ins) labeled with europium(iii) com...

Synthesis of the IGF-II-like hormone vesiculin using regioselective formation of disulfide bonds.

Diabetes mellitus, characterised by hyperglycemia and altered β-cell function, is an increasingly common disorder affecting millions of individuals world-wide. While therapeutic regimens exist to man...

Calcium co-ingestion augments postprandial glucose-dependent insulinotropic peptide1-42, glucagon-like peptide-1 and insulin concentrations in humans.

PURPOSE: This study determined whether calcium co-ingestion potentiates postprandial GIP1-42 and GLP-1 concentrations in humans and the concomitant impact on insulin, appetite sensations and substrate...

The influence of growth hormone/insulin-like growth factor deficiency on prostatic dysplasia in pbARR2-Cre, PTEN knockout mice.

Background:Elevated insulin-like growth factor-I (IGF-I) serum levels and phosphatase and tensin homolog (PTEN) loss are prostate cancer (PCa) risk factors that enhance androgen-responsive and castrat...

Dupilumab in Persistent Asthma with Elevated Eosinophil Levels.

Background Moderate-to-severe asthma remains poorly treated. We evaluated the efficacy and safety of dupilumab (SAR231893/REGN668), a fully human monoclonal antibody to the alpha subunit of the interl...

Inhibiting Interleukin-4 and Interleukin-13 in Difficult-to-Control Asthma.

One of the most challenging aspects of the clinical management of asthma is determining how to treat patients whose condition is poorly controlled despite the use of inhaled glucocorticoids and long-a...

Poor pregnancy outcome in women with type 1 diabetes is predicted by elevated HbA1c and spikes of high glucose values in the third trimester.

Abstract Objective: To analyse data from a randomised, controlled study of prandial insulin aspart vs. human insulin, both with NPH insulin, in pregnant women with type 1 diabetes for potential factor...

Ginsenoside Re reduces insulin resistance through activation of PPAR-γ pathway and inhibition of TNF-α production.

Panax ginseng is a well-known traditional Chinese medicine and has been used for treatment of various diseases for more than four thousand years in Asia. Ginseng saponins or ginsenosides, the active c...

News Articles [ 5230 Associated News Articles listed on BioPortfolio]

Pfizer Guards Viagra Sales, Moves Against Tainted Supplements

A Pfizer study that finds 81% of sexual performance products claiming to be natural have undeclared pharmaceuticals could pressure FDA to increase enforcement and Congress to boost funding for the eff...

Pfizer spaltet Tierarzneisparte Zoetis endgültig ab

Der amerikanische Pharmakonzern Pfizer trennt sich endgültig von seiner Tierarzneisparte Zoetis. Nachdem Pfizer im Februar ein Fünftel der Veterinärsparte an die Börse gebracht hat, will der US-Ko...

Could Fish Oil Bolster Insulin Sensitivity? (CME/CE)

(MedPage Today) -- The long-chain fatty acids found in fish oil moderately increased levels of the hormone adiponectin, which could have protective effects on insulin sensitivity, according to this me...

Pfizer to spin off Zoetis stake to shareholders

(Reuters) - Pfizer Inc said on Wednesday it will spin off its majority stake in animal health business Zoetis Inc to shareholders by allowing them to swap Pfizer stock for Zoetis stock at a 7 percent...

UPDATE 1-Pfizer to spin off Zoetis stake to shareholders

May 22 (Reuters) - Pfizer Inc said on Wednesday it will spin off its majority stake in animal health business Zoetis Inc to shareholders by allowing them to swap Pfizer stock for Zoetis stock at a 7 p...

BRIEF-Pfizer up in premarket after plans to unwind remaining majority stake in Zoetis

NEW YORK, May 22 (Reuters) - Pfizer Inc : * Up 2.2 percent to $29.40 in premarket after plans to unwind remaining majority stake in Zoetis

Pfizer plans to unwind remaining majority stake in Zoetis

May 22 (Reuters) - Pfizer Inc said on Wednesday that it would unwind its remaining stake in animal health business Zoetis Inc through an exchange offer in which shareholders can swap Pfizer stock for...

Zoetis To File Registration Statement; Comments on Pfizer’s Split-off Plans for Remaining Interest in Zoetis

Zoetis Inc. (NYSE: ZTS) announced it intends to file a Registration Statement on Form S-4 with the Securities and Exchange Commission (SEC) today in connection with the proposed e...

Pfizer Announces Plan for Split-Off of Zoetis

Provides Pfizer shareholders an option for a tax-free exchange Better positions Pfizer to focus on its core business as an innovative biopharmaceutical c...

Insulin Pump Therapy Provides Better Glycemic Control Among Type 1 Diabetics, According to Kantar Health Research

New results from the National Health and Wellness Survey show patients with type 1 diabetes have significantly lower HbA1C levels. New York, NY (PRWEB) May 22, 2013 Patients with type 1 diabetes (T1D...

Events [ 1 Associated Events listed on BioPortfolio]

Pharma Data Analytics

Evolving Big Data Management to Advance Data Analytics, Business Forecasting, and Expedite Decisions

Companies [ 57 Associated Companies listed on BioPortfolio]

Zoetis Inc.

Zoetis (zō-EH-tis) is the leading animal health company, dedicated to supporting its customers and their businesses. Building on a 60-year history as the animal health business...

Defymed

Defymed is a spin -off of the “Centre Europeen d’etude du Diabete”  (CeeD) which has been working on the conception of a bio-artificial pancreas since 1996. This work was ca...

Pfizer, Inc.

Pfizer is prioritizing its research and development efforts in areas with the greatest scientific and commercial promise: immunology and inflammation, oncology, cardiovascular and metabolic diseases...

Kamada, Ltd.

Kamada is a public biopharmaceutical company (TASE: KMDA) developing, producing and marketing a line of specialty life-saving biopharmaceuticals. Licensed and marketed worldwide,...

Activaero

Activaero is the world leader in the design of controlled breathing drug delivery technologies that maximize the efficiency and precision of inhaled drugs. These innovative techno...

Aviir, Inc.

Founded in 2005 by cardiologists and researchers from the Stanford University School of Medicine , Aviir is focused on the discovery, development and commercialization of innovati...

MDxHealth SA

MDxHealth is a leading molecular diagnostics company that develops and commercializes oncology-based molecular diagnostic testing for personalized medicine. The company’s tes...

Aravo Solutions, Inc.

The world's best-run businesses utilize Aravo's SaaS-based Supplier Lifecycle Management (Aravo Enterprise) and B2B information and collaboration (Aravo Assure) solutions to find...

Ember Therapeutics

Ember Therapeutics is a product-focused company harnessing breakthroughs in brown fat biology and insulin sensitization to revolutionize the treatment of metabolic disease. Today...

Affinnova

Affinnova is a high-growth software and services firm that enables innovative companies to drive better ideas to market faster. Unlike conventional market research, our patented s...

Clinical Trials [ 1951 Associated Clinical Trials listed on BioPortfolio]

Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants

To determine whether or not inhaled nitric oxide (iNO) safely decreases the incidence of chronic lung disease (CLD) in premature infants.

Effects of Exenatide and Insulin Glargine in Subjects With Type 2 Diabetes

This Phase 3, open-label, multicenter study is designed to compare the effects of exenatide and insulin glargine (Lantus® injection) on beta-cell function in patients with type 2 diabetes...

Calcineurin Inhibitor-free, Steroid-free Immunosuppressive Regimen in Simultaneous Islet-Kidney Transplantation for Uremic Type 1 Diabetic Patients

The investigators hypothesize that a calcineurin inhibitor-free, steroid-free, co-stimulatory blockade-based immunosuppressive regimen, in combination with a GLP-1 agonist, will reduce the...

Exercise and Metformin in Colorectal and Breast Cancer Survivors

Metformin is a medication that is commonly used in the treatment of diabetes. Recently small studies in cancer patients without diabetes suggest that metformin may benefit in lowering ins...

The Role of Endocannabinoids in Insulin Production and Action

Background: - The endocannabinoid system is involved in different body functions and processes. It helps regulate appetite and mood, and sends signals to the nervous system. It may also b...

The Effect of Exercise Intervention on Insulin Resistance in Non-alcoholic Fatty Liver Disease (NAFLD)

This project examines the effects of a 4 month structured exercise intervention program in patients with non-alcoholic fatty liver disease (NAFLD). We will examine changes in total and dep...

Infergen, Ribavirin, and Avandia in Insulin Resistant, Chronic Hepatitis C Patients Who Are Previous Relapsers or Nonresponders to Pegylated Interferon and Ribavirin

Genotype 1 hepatitis C virus (HCV) patients who did not respond (did not lose virus during treatment) or relapsed (virus went away on treatment but came back after treatment was stopped) a...

Exhale (R) Stent for Emphysema

Current treatment for emphysema is limited to measures that include inhaled oxygen, bronchodilators, anti-inflammatory drugs and pulmonary rehabilitation. Highly invasive procedures such...

Evaluation of an ICU Hyperglycemia Protocol Using Insulin Aspart

In response to the evidence supporting “tight” glucose control (70 – 110) in the critical care setting, the MMH ICU developed a protocol utilizing regular intravenous insulin. This p...

Janssen - Glucose Regulation/Risp/Olanz

Abnormalities in peripheral glucose regulation and type 2 diabetes can occur more commonly in individuals with schizophrenia than in healthy subjects or in other psychiatric conditions. A...

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Medical and Biotech [MESH] Definitions

Actinobacteria

Class of BACTERIA with diverse morphological properties. Strains of Actinobacteria show greater than 80% 16S rDNA/rRNA sequence similarity among each other and also the presence of certain signature nucleotides. (Stackebrandt E. et al, Int. J. Syst. Bacteriol. (1997) 47:479-491)

Persistent Hyperinsulinemia Hypoglycemia Of Infancy

A form of nontransient HYPOGLYCEMIA, unique to infancy, due to autosomal recessive mutations of the sulfonylurea receptor gene on CHROMOSOME 11. Defects in the sulfonylurea receptors (ATP-BINDING CASSETTE TRANSPORTERS) on the PANCREATIC BETA CELLS prevent negative feedback of GLUCOSE-regulated INSULIN release thus resulting in HYPERINSULINEMIA. Clinical phenotype includes SEIZURES; COMA; and often large BIRTH WEIGHT for GESTATIONAL AGE.

Thiazolidinediones

THIAZOLES with two keto oxygens. Members are insulin-sensitizing agents which overcome INSULIN RESISTANCE by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma).

Laron Syndrome

An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5.

Insulin, Long-acting

Insulin formulation containing substance which delays or retards time period of the absorption of insulin.

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