Interdigital Nerve Pain - Biotech, Pharma and Life Science Channel
PubMed Articles
Intrapartum sacral stress fracture due to pregnancy-related osteoporosis: a case report.
Low back pain (LBP) and hip pain frequently occur during pregnancy and postpartum period. Although pelvic and mechanic lesions of the soft tissues are most responsible for the etiology, sacral fractur...
Brainstem auditory evoked potentials and somatosensory evoked potentials in Chiari malformation.
INTRODUCTION. Chiari malformations (CM) include a series of congenital anomalies involving the descent of the cerebellar tonsils below the foramen magnum, which may be associated with compression in t...
Case Description-An 8-week-old female domestic shorthair cat was treated for patent ductus arteriosus (PDA) with surgical ligation. Seven weeks postoperatively, the cat was evaluated because of increa...
A novel benzazepinone sodium channel blocker with oral efficacy in a rat model of neuropathic pain.
A series of benzazepinones were synthesized and evaluated for block of Nav1.7 sodium channels. Compound 30 from this series displayed potent channel block, good selectivity versus other targets, and d...
Does opioid pain medication use affect the outcome of patients with lumbar disc herniation?
STUDY DESIGN.: Subgroup analysis of prospective, randomized cohort. OBJECTIVE.: To review the results of patients who received opioid pain medications during treatment compared with that of patients w...
Norepinephrine potentiates proinflammatory responses of human vaginal epithelial cells.
The vaginal epithelium provides a barrier to pathogens and recruits immune defenses through the secretion of cytokines and chemokines. Several studies have shown that mucosal sites are innervated by n...
Skin vasodilation and analgesic effect of a topical nitric oxide-releasing hydrogel.
New approaches based on topical treatments are needed for treating pain and impaired dermal blood flow. We used a topical Pluronic F127 hydrogel containing S-nitrosoglutathione (GSNO) as a prodrug to...
Clinical Practice: Chronic fatigue syndrome.
The diagnosis chronic fatigue syndrome (CFS) was conceptualized in the mid-1980s. It is a clinically defined condition characterized by severe and disabling new onset fatigue with at least four additi...
The modified Harrington procedure for metastatic peri-acetabular bone destruction.
PURPOSE: We describe the outcome in a series of patients treated for metastatic peri-actetabular and iliac bone destruction using a modified technique of Harrington's procedure. METHODS: Between 2006...
Bisphosphonate (BP)-related osteonecrosis of the jaw (BRONJ) presents with necrotic bone in the mouth in the setting of BP exposure. It has been studied in cancer patients taking high-dose BP, but BRO...
News Articles
Safinamide improves responder rates in fluctuating Parkinson's patients in Phase III study
Newron Pharmaceuticals S.p.A. ("Newron"), a research and development company focused on novel CNS and pain therapies, and its partner Zambon S.p.A., a pharmaceutical company strongly committed to the...
Spinal infection at contaminated drug injection site detected using contrast-enhanced MRI screening
Magnetic resonance imaging (MRI) at the site of injection of a contaminated lot of a steroid drug to treat symptoms such as back pain resulted in earlier identification of patients with probable or co...
Vertos Medical Raises $23 Million in Series E Financing
ALISO VIEJO, Calif., June 19, 2013 /PRNewswire-USNewswire/ -- Vertos Medical Inc., which has pioneered the mild® procedure -- a safe, outpatient procedure that can help patients diagno...
Researchers discover a rational source of pain in skin of patients with fibromyalgia
Fibromyalgia, a painful condition affecting approximately 10 million people in the U.S., is not imaginary after all, as some doctors have believed. A discovery, published this month in PAIN MEDICINE (...
Woman Experiences Astonishing Recovery from Fibromyalgia
SHELBY TOWNSHIP, Mich., June 19, 2013 /PRNewswire/ -- Heather Shinsky experienced the full range of trauma that is typical to the two to four percent of the population suffering from fibromyalgia...
PRAC recommends restricting the use of flupirtine-containing medicines
The EMA’s Pharmacovigilance Risk Assessment Committee (PRAC) has concluded its review of flupirtine-containing medicines and recommended restrictions in their use. The Committee recommended that ora...
On June 3, 2013, the International Adhesions Society (IAS) presented recommendations to the Interagency Pain Research Coordinating Committee (IPRCC), advocating for efforts to address gender disparity...
Rational Biological Source Of Pain Found In The Skin Of Patients With Fibromyalgia
Fibromyalgia, a painful condition affecting approximately 10 million people in the U.S., is not imaginary after all, as some doctors have believed. A discovery, published this month in PAIN MEDICINE (...
Spinal Injection Therapy for Low Back Pain Spinal Injection Therapy for Low Back Pain
Low back pain is commonly reported by patients in primary care and will affect most adults at some time during their lifetime. The socioeconomic burden of low back pain is high. In the United States,...
Nerve Cell Properties Altered By Diet Restored By Bariatric Surgery
Understanding how gastric bypass surgery changes the properties of nerve cells that help regulate the digestive system could lead to new treatments that produce the same results without surgery, accor...
Events
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Companies
Baptist Health System is a leading provider of health care in San Antonio and South Texas. Baptist Health System includes five acute-care hospitals (Baptist Medical Center, North Central Baptist Hospi...
Vertical Pharmaceuticals, Inc.
Vertical Pharmaceuticals, Inc. is a privately owned pharmaceutical company founded in 2003 with a clear focus in mind â to develop, market, and acquire products offering ther...
NeuroMetrix, Inc. was founded in June 1996 as a spin-off from the Harvard-M.I.T. Division of Health Sciences and Technology. The Company’s mission is to: Create value for our customers by developi...
NeuroMetrix is a science-based health care company transforming patient care through neurotechnology. To date, our focus has been primarily on the assessment of neuropathies. We a...
Ocular Therapeutix, Inc. is a privately held company based in Bedford, MA, focused on the development and commercialization of ophthalmic therapeutic products using its proprietar...
Dr. Reddyâs Laboratories Ltd. (NYSE: RDY) is an integrated global pharmaceutical company, committed to providing affordable and innovative medicines for healthier lives. Thro...
SYGNIS Pharma AG, headquartered in Heidelberg, is a specialty pharmaceutical company listed on the Prime Standard of the German stock exchange. The Company is focused on the research, development an...
Civitas is a privately held pharmaceutical company focused on developing products with a clinically proven dry powder pulmonary delivery platform. The proprietary dry powder and d...
Kineta is a Seattle-based privately held biotechnology company specializing in clinical advancement of novel drug candidates derived from leading edge scientific research. Our wor...
THE Surgical Hospital of Phoenix
THE Surgical Hospital of Phoenix, the first licensed surgical specialty facility of its kind in Arizona, first opened its doors in May of 2005. Specializing in spine, orthopedics,...
Clinical Trials
A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-181)(COMPLETED)
The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.
Naproxen Sodium Extended-Release Actual Use Study
The purpose of this Study is to assess how subjects will use the investigational product in an uncontrolled, naturalistic environment.
Safety of Driving After Minor Surgery With Monitored Anesthesia Care
Patients are currently advised to refrain from driving motor vehicles or using public transportation unescorted for a 24 hour period if they undergo any minor ambulatory surgical procedure...
A Trial of Gabapentin in Vulvodynia: Biological Correlates of Response
The Specific aims of this project are to (1) test the prediction that pain from tampon insertion (primary outcome measure) is lower in PVD patients when treated with gabapentin compared to...
The purpose of this study is to see if different types of surgery for lung cancer have different effects on quality of life and pain. What we learn from this study may help us find new way...
Direct Stimulation Of Spinal Nerve Roots To Determine Sensory And Motor Innervation Patterns
The purpose of this study is to collect data while monitoring muscles and nerves during spine surgery. The data being collected and analyzed will be used to learn more about how the body's...
Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain
Noxious stimuli occurring intraoperatively and postoperatively generate central sensitization, decreasing pain thresholds and ultimately increasing analgesic requirements. The pathophysiol...
Pelvic Pain in Women With Endometriosis
This study will examine pelvic pain associated with endometriosis and explore better approaches to treatment. In women with endometriosis, uterine tissue grows outside the uterus. Standa...
Low-level Laser Therapy on Temporomandibular Disorder
The purpose of this study is to assess the effect of low-level laser on pain, occlusal contacts, mandibular movements and electromyography activity in the masseter and temporal muscles in...
USG Nerve Blocks for ACL Reconstruction
Anterior cruciate ligament reconstruction is a routine surgical procedure. Traditional femoral/sciatic block combinations effectively reduce postoperative pain, but results in considerable...
Videos
Ball of Foot Pain
Ball of the foot pain with numbness and tingling is a common complaint in my Grapevine, Texas office. The most common reason is a Morton's neuroma. I'm not e...
Medical and Biotech [MESH] Definitions
Receptor, Ephb2
An eph family receptor found widely expressed in embryonic and adult tissues. High levels of EphB2 receptor are observed in growing AXONS and NERVE FIBERS. Several isoforms of the protein exist due to multiple alternative mRNA splicing.
Ephrin-a3
A GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin with a high affinity for the EPHA3 RECEPTOR; EPHA5 RECEPTOR; EPHA6 RECEPTOR; EPHA7 RECEPTOR; and EPHA8 RECEPTOR. It is found primarily in NERVE TISSUE.
Nerve Fibers, Unmyelinated
A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the unmyelinated nerve fibers are small. The axons to SCHWANN CELLS ratio is greater in the unmyelinated nerve fibers than that in the myelinated fiber (NERVE FIBERS, MYELINATED) which is 1:1. Usually several axons are surrounded by a single Schwann cell in the unmyelinated nerve fibers. Therefore, each unmyelinated fiber is not completely covered by the MYELIN SHEATH formed by the Schwann cell. Unmyelinated nerve fibers conduct impulses at low velocities. They represent the majority of peripheral sensory and autonomic fibers. They are also found in the spinal cord and brain.
Fasciitis, Plantar
Inflammation of the thick tissue on the bottom of the foot (plantar fascia) causing HEEL pain. The plantar fascia (also called plantar aponeurosis) are bands of fibrous tissue extending from the calcaneal tuberosity to the TOES. The etiology of plantar fasciitis remains controversial but is likely to involve a biomechanical imbalance. Though often presenting along with HEEL SPUR, they do not appear to be causally related.
Metatarsalgia
Pain in the region of the METATARSUS. It can include pain in the METATARSAL BONES; METATARSOPHALANGEAL JOINT; and/or intermetatarsal joints (TARSAL JOINTS).
