Interferon beta-1a rDNA Biopartners - Biotech, Pharma and Life Science Channel
PubMed Articles
KCNN4 Channels participate in the EMT induced by PRL-3 in colorectal cancer.
Studies have shown that phosphatase of regenerating liver-3 (PRL-3) promotes the invasion, migration, and metastasis of human tumor cells by facilitating an epithelial-mesenchymal transition (EMT). Ho...
Longidorus aetnaeus Roca, Lamberti, Agostinelli & Vinciguerra, 1986 is reported for the first time from Iran and Ajaria (Georgia). Morphological and morphometric data are provided for two Iranian and...
A population of Xiphinema macroacanthum Lamberti, Roca & Agostinelli, 1989 originating from olive orchards in Brindisi, Italy and containing both adults and all juvenile stages, is described and illus...
Alpha (α) particles and low-energy beta (β) particles present minimal risk for external exposure. While these particles can induce leukemia and bone cancer due to internal exposure, they can also be...
JAK/STAT signalling is essential for anti-viral immunity, making IFN-α an obvious anti-viral therapeutic. However, many HCV+ patients fail treatment, indicating that the virus blocks successful IFN-Î...
Although larvae of the genus Trichinella are the most common parasite species detected in vertebrate muscles using artificial digestion, nematode larvae belonging to other genera are sometimes detecte...
Genus Sphingomonas has received increasing attentions due to its somewhat unique metabolic versatilities in the contaminated environment. However, due to the lack of genus-specific primers, the ecolog...
Nitrate is the second largest contaminant of agriculture soil after pesticides. It also is a major pollutant from nuclear and metallurgical operations. Conventional methods for nitrate removal suffers...
Plant protection through siderophore producing rhizobacteria (SPR) has emerged as a sustainable approach for crop health management. In present study, 220 bacteria isolated from tomato rhizosphere wer...
Anti-transforming growth factor beta (TGF-β) therapy in patients with myelofibrosis.
News Articles
COPD patients’ CV risk increased with beta-agonists and anticholinergics
The new use of inhaled long-acting bronchodilators — beta-agonists and anticholinergics — is associated with increased cardiovascular risk in patients with chronic obstructive pulmonary disease (...
-- Once-Daily Sofosbuvir will Receive an Accelerated Assessment by EMA; Designation Granted to New Medicines of Major Public Health Interest --...
Biogen Idec files BLA for MS drug Plegridy in USA
US biotech company Biogen Idec (Nasdaq: BIIB) has submitted a Biologics License Application (BLA) to the US Food and Drug Administration for approval of Plegridy (peginterferon beta-1a), the company's...
In tracks of Tecfidera success, Biogen seeks Plegridy nod in MS
With Tecfidera (dimethyl fumarate; BG-12) looking to be a success in the multiple sclerosis marketplace, Biogen Idec is ready to take the plunge with its next product – Plegridy (peginterferon...
ORLANDO, Fla., May 21, 2013 /PRNewswire/ -- Janssen R&D Ireland (Janssen) today announced primary efficacy and safety results from the global Phase 3 PROMISE study demonstrating that use of t...
— EMA Submission Planned in the Coming Weeks — Today Biogen Idec (NASDAQ: BIIB) announced it has submitted a Biologics License Application (BLA) to the U.S. Food an...
Melissa Productions Psychic CEO Raises Awareness for Type 1 Diabetes on Kiss 95.1
Melissa Productions psychic CEO raises awareness for type 1 diabetes on Kiss 95.1 by agreeing to provide the morning show host’s, Maney of ‘Drex and Maney’, wife a psychic consultation with proc...
Biogen Idec seeks FDA BLA approval for PLEGRIDY to treat multiple sclerosis
Today Biogen Idec announced it has submitted a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for approval of PLEGRIDY (peginterferon beta-1a), the company's pegyla...
Elan to buy AOP, NewBridge stake, spin out ELND005
Elan Corp. plc (NYSE:ELN) announced two proposed acquisitions on Monday, including a proposal to buy rare disease company AOP Orphan Pharmaceuticals AG (Vienna, Austria) for EUR 175.7 million ($225.5...
CV Risks of Inhaled Bronchodilators for COPD
The controversy continues over the cardiovascular side effects of both long-acting beta-agonist and long-acting anticholinergic drugs when newly prescribed for the management of chronic obstructiv...
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Companies
Scientific excellence that achieves new standards of care drives the company's work. 17 products are currently in clinical development addressing a variety of key medical needs.With patients in more t...
PBL InterferonSource, a division of Pestka Biomedical Laboratories based in Piscataway, N.J., USA, is the world’s leading supplier of interferon products to the life science...
The International Society for Interferon and Cytokine Research (ISICR), based in Bethesda, Md., is a non-profit organization devoted to interferon, cytokine and chemokine r...
Nuron Biotech is developing novel biologics and vaccines for the prevention and treatment of neurodegenerative and infectious diseases. Its team of industry veterans is committed...
ZymoGenetics is a biopharmaceutical company focused on the development and commercialization of therapeutic proteins for the treatment of human diseases. The company has developed...
EMD Serono, Inc., an affiliate of Merck KGaA, Darmstadt, Germany, is a leader in the US biopharmaceutical arena, integrating cutting-edge science with unparalleled patient support...
Vitro Diagnostics, Inc., dba Vitro Biopharma (OTCBB: VODG) (http://www.vitrobiopharma.com), owns U.S. patents for production of a fertility drug, immortalization of pituitary cell...
Avid Radiopharmaceuticals, Inc.
Avid Radiopharmaceuticals is a leader in the development of molecular imaging products with the potential for earlier and more effective detection, diagnosis and monitoring of maj...
EMD Serono, Inc., an affiliate of Merck KGaA, Darmstadt, Germany, is a leader in the US biopharmaceutical arena, integrating cutting-edge science with unparalleled patient support...
Genetix Pharmaceuticals, Inc. is an emerging leader in treatments for severe genetic disorders based on a breakthrough gene therapy platform that uses a patient’s own genes t...
Clinical Trials
Effects of Exenatide and Insulin Glargine in Subjects With Type 2 Diabetes
This Phase 3, open-label, multicenter study is designed to compare the effects of exenatide and insulin glargine (Lantus® injection) on beta-cell function in patients with type 2 diabetes...
Study assessing cognitive function and physical activity in people with relapsing remitting multiple sclerosis.
RATIONALE: Drugs used in chemotherapy, such as azacitidine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Interfe...
HRN-003 STUDY SYNOPSIS OBJECTIVE: To compare the Sustained Virologic Response (SVR) of PEGIntron plus ribavirin among patients receiving a fixed dose of PEGIntron versus weighted-adjusted...
Objectives: Primary To evaluate the safety, tolerability, and efficacy of Peginterferon a-2a plus Ribavirin for the treatment of chronic hepatitis C (CHC) infection in persons co-infected...
Tc-99m Renography and Cisplatin-Induced Nephrotoxicity
Cisplatin is a heavy-metal complex widely used in the treatment of a variety of malignancies, including small cell and non-small cell lung cancer, ovarian, bladder, head and neck, esophage...
Paroxetine for the Treatment of Interferon Related Side Effects for Hepatitis C
A.OVERVIEW This is a 26 week study examining the ability of paroxetine (Paxil) to prevent the development of depression and neurotoxicity in patients receiving either 3 million units of...
Genotype 1 hepatitis C virus (HCV) patients who did not respond (did not lose virus during treatment) or relapsed (virus went away on treatment but came back after treatment was stopped) a...
The purpose of this study is to see which of two doses of PEG (polyethylene glycol) interferon alfa-2b in combination with Ribavirin for 48 weeks is more effective at elimination of hepati...
Pegylated Interferon-Alpha-2a in Patients With Malignant Melanoma Stage IIA-IIIB
The purpose of this study is to evaluate the efficacy and safety of adjuvant treatment with pegylated interferon-α-2a (PEG-IFN) vs. 'low dose' interferon-α-2a in patients with malignant...
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Medical and Biotech [MESH] Definitions
Boehmeria
A plant genus of the family URTICACEAE. Members contain cryptopleurine, beta-sitosterol, daucosterol and 19 alpha-hydroxyursolic acid.
Adaptor Protein Complex Beta Subunits
A family of large adaptin protein complex subunits of approximately 90-130 kDa in size.
Viridans Streptococci
A large heterogeneous group of mostly alpha-hemolytic streptococci. They colonize the respiratory tract at birth and generally have a low degree of pathogenicity. This group of species includes STREPTOCOCCUS MITIS; STREPTOCOCCUS MUTANS; STREPTOCOCCUS ORALIS; STREPTOCOCCUS SANGUIS; STREPTOCOCCUS SOBRINUS; and the STREPTOCOCCUS MILLERI GROUP. The latter are often beta-hemolytic and commonly produce invasive pyogenic infections including brain and abdominal abscesses.
Streptococcus Milleri Group
A subset of VIRIDANS STREPTOCOCCI, but the species in this group differ in their hemolytic pattern and diseases caused. These species are often beta-hemolytic and produce pyogenic infections.
Host Factor 1 Protein
An integration host factor that was originally identified as a bacterial protein required for the integration of bacteriophage Q beta (ALLOLEVIVIRUS). Its cellular function may be to regulate mRNA stability and processing in that it binds tightly to poly(A) RNA and interferes with ribosome binding.
