Intestinal Obstruction - Biotech, Pharma and Life Science Channel
PubMed Articles
The decoction of Terminalia chebula fruit is an ayurvedic remedy whose prolonged oral administration is prized as a generic intestinal and hepatic detoxifying agent. Its administration is suggested al...
Intestinal infection with Trichinella spiralis induces distinct, regional immune responses.
The aim of this study was to evaluate differences between the small and large intestines (SI and LI) with regard to colonization and immunity during infection with Trichinella spiralis. In orally infe...
Protection against Trichinella infections has been achieved using various parasite antigens and adjuvants. Recently, we reported that immunization of mice with an attenuated Salmonella strain displayi...
The purpose of this study was to determine the protein changes in Trichinella spiralis muscle larvae (ML) after in vitro co-culture with intestinal epithelial cells, and to analyze the changed protein...
Nutritional therapy in acute pancreatitis.
Acute pancreatitis is a frequent clinical entity in the West. About 80% of patients with acute pancreatitis develop edematous pancreatitis, while 20% develop necrotizing pancreatitis: The latter is a...
Biodegradable stent for the treatment of a colonic stricture in Crohn's disease.
Biodegradable polydioxanone stents were developed for the treatment of refractory benign esophageal strictures but have been suggested as a new therapeutic option for intestinal strictures. The primar...
Primary Budd-Chiari syndrome in a 3-year-old boy with homozygous factor V Leiden G1691A mutation.
Budd-Chiari syndrome (BCS) is an uncommon disorder characterized by obstruction of hepatic venous outflow. The primary BCS is a rare disease with an incidence about 0.2 per million inhabitants per yea...
Although intestinal flora are crucial in maintaining immune homeostasis of the intestine, the role of intestinal flora in immune responses at other mucosal surfaces remains less clear. Here, we show t...
Dysbiosis in inflammatory bowel diseases: the oxygen hypothesis.
The healthy intestine is characterized by a low level of oxygen and by the presence of large bacterial communities of obligate anaerobes. Dysbiosis of the gut microbiota has been reported in patients...
Synthesis and Biopharmaceutical Studies of JLTN as Potential Dasatinib Prodrug.
Dasatinib was identified as a potent orally administered Src/Abl kinase inhibitor with excellent antiproliferative activity against Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia in chr...
News Articles
Boston Scientific Presents Clinical Data at Digestive Disease Week®
NATICK, Mass., May 17, 2013 /PRNewswire/ -- Boston Scientific Corporation (NYSE:BSX) is scheduled to participate in Digestive Disease Week (DDW®) 2013, May 18-21 in Orlando, Fla. More...
Combined wood and tobacco smoke exposure increases risk and symptoms of COPD
(American Thoracic Society) People who are consistently exposed to both wood smoke and tobacco smoke are at a greater risk for developing chronic obstructive pulmonary disease and for experiencing mor...
Coffee Linked To Lower Risk Of Autoimmune Liver Disease
redOrbit Staff & Wire Reports - Your Universe Online Regular coffee consumption has been linked to a reduced risk of the autoimmune liver disease primary sclerosing cholangitis (PSC), according t...
Type: Original PaperPurposeSuperior bioavailability of BCS Class 2 compounds incorporated into SNEDDS was previously reported. This study aims to elucidate the underlying mechanisms accountable for th...
Tolerance: The origins of colonic TReg cells
High-throughput TCR sequencing suggests that most intestinal TReg cells derive from the thymus.
Mucosal immunology: TLRs get rhythm
TLR expression in intestinal epithelial cells is under circadian control, leading to microbiota-dependent oscillatory immune signalling.
FDA approves GSK’s Breo Ellipta to treat COPD
The FDA has approved GlaxoSmithKline and Theravance’s Breo Ellipta (fluticasone furoate and vilanterol inhalation powder) for the long-term, once-daily, maintenance treatment of airflow obstruction...
Studies Show Improved IBD Diagnoses and Treatments
NEW YORK, NY--(Marketwired - May 17, 2013) - Four important findings from the Pediatric Resource Organization for Kids with Inflammatory Intestinal Digestive Diseases (PRO-KIIDS) will be presented th...
Researchers see potential in deploying Akkermansia bacteria to understand and treat obesity
A dominant and useful bacterium called Akkermansia muciniphila is present in the intestinal system of all humans, from babies to the elderly. This microorganism is found in the intestinal mucus layer...
Gut Bacteria Byproduct Predicts Heart Attack
A microbial byproduct of intestinal bacteria contributes to heart disease and serves as an accurate screening tool for predicting future...
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Companies
Dr. Reddyâs Laboratories Ltd. (NYSE: RDY) is an integrated global pharmaceutical company, committed to providing affordable and innovative medicines for healthier lives. Thro...
NxThera develops medical technologies to treat a variety of endourology conditions, including BPH. The Companyâs RezÅ«m System delivers vapor directly to the prostate to re...
GlycoVaxyn is developing a broad portfolio of novel conjugate vaccines against common severe bacterial infections based on its unique, proprietary in-vivo glycosylation platform....
Midway Pharmaceuticals is an emerging pharmaceutical company focused on developing proprietary drugs for the treatment of gastrointestinal diseases. The companyâs platform te...
NPS Pharmaceuticals is developing new treatment options for patients with rare gastrointestinal and endocrine disorders. The company is currently advancing two Phase 3 registratio...
Clinical Trials
patients who had failed previous H. pylori eradication on standard triple therapy were randomized into two regimens: 1, esomeprazole (20 mg b.i.d), tripotassium dicitrate bismuthate (300 m...
Vinblastine and Methotrexate in Children With Pulmonary Vein Stenosis
To evaluate the efficacy of the chemotherapeutic agents vinblastine and methotrexate in the treatment of two groups of children with multivessel pulmonary vein stenosis. Group 1 will cont...
Glutamine and Intestinal Protein Metabolism
Gut barrier plays a major role in defence of the organism. During catabolic states, like major surgery or inflammation, gut barrier could be altered. It has been reported that preoperative...
Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-Year Manometric Follow-Up
Small bowel involvement is still recognized to be associated with great morbidity and mortality in SSc patients, leading particularly to malabsorption and intestinal pseudo-obstruction. In...
Enteral Nutrition in Liver Cirrhosis
Malnutrition is frequently occurring in patients with liver cirrhosis and is associated with a poorer outcome, as it determines life quality and affects both morbidity and mortality. Long...
Abstract Biliary atresia (BA) is an idiopathic, progressive, and fatal disease if untreated. Since Kasai first introduced the operation for BA in 1959, there have been encouraging results...
Esophageal Metaplasia Using a Novel Antibody: Reversibility by Proton Pump Inhibitor
In this project, we are trying to identify patients with the earliest signs of abnormality in the lining of the lower part of the food pipe (or esophagus) known as intestinal metaplasia (I...
Lipoproteins are large complexes of molecules that transport lipids (primarily triglycerides and cholesterol) through the blood. The intestine has traditionally been viewed as a 'passive'...
Stenting in Renal Dysfunction Caused by Atherosclerotic Renal Artery Stenosis
Background: Atherosclerotic renal artery stenosis (ARAS) is associated with progressive loss of renal function and is one of the most important causes of renal failure in the elderly. Cur...
Mass Treatment T Solium Community Study
Investigators from Cayetano Heredia University and Johns Hopkins University are doing this study. They want to see how people and pigs get infected with a parasite, called cysticercus (kno...
Videos
Small Bowel Obstruction
Dr. Carlo Oller, emergency physician, talks about a Small Bowel Obstruction.
Medical and Biotech [MESH] Definitions
Cholecystitis, Acute
Acute inflammation of the GALLBLADDER wall. It is characterized by the presence of ABDOMINAL PAIN; FEVER; and LEUKOCYTOSIS. Gallstone obstruction of the CYSTIC DUCT is present in approximately 90% of the cases.
Intestinal Polyposis
The growth of INTESTINAL POLYPS. Growth processes include neoplastic (ADENOMA and CARCINOMA) and non-neoplastic (hyperplastic, mucosal, inflammatory, and other polyps).
Steatorrhea
A condition that is characterized by chronic fatty DIARRHEA, a result of abnormal DIGESTION and/or INTESTINAL ABSORPTION of FATS.
Intestinal Volvulus
A twisting in the intestine (INTESTINES) that can cause INTESTINAL OBSTRUCTION.
Ileus
A condition caused by the lack of intestinal PERISTALSIS or INTESTINAL MOTILITY without any mechanical obstruction. This interference of the flow of INTESTINAL CONTENTS often leads to INTESTINAL OBSTRUCTION. Ileus may be classified into postoperative, inflammatory, metabolic, neurogenic, and drug-induced.