Iron Deficiency Anemia - Biotech, Pharma and Life Science Channel
PubMed Articles
This work investigates the possibility of combining Monte Carlo (MC) simulations to a denoising algorithm for the accurate prediction of images acquired using amorphous silicon (a-Si) electronic porta...
Evidence of oxidative stress in young and aged DJ-1-deficient mice.
Loss of DJ-1 function contributes to pathogenesis in Parkinson's disease. Here, we investigate the impact of aging and DJ-1 deficiency in transgenic mice. Ventral midbrain from young DJ-1-deficient mi...
TIF1γ (transcription intermediary factor 1 gamma), which belongs to transcription intermediary factor 1 family, is an inhibitor of the TGF-β/Smad signaling pathway and could inhibit the signal trans...
Herein we report the rational design of new phosphopeptides for control of nucleation, growth and aggregation of water-soluble, superparamagnetic iron-iron oxide core-shell nanoparticles. The use of t...
In the critically ill liver patient, nutrition support is not very different from that given for other illnesses. In hyperacute liver failure, nutrition support is of less importance than in the other...
Nonlinear optics: A hemicyanine-incorporating silicalite-1 film with second-order nonlinear optical properties supported on a glass plate was prepared. For the nonlinear optical properties of this mat...
Inelastic neutron scattering (INS) has been used to obtain the vibrational spectrum of a technical-grade iron-based Fischer-Tropsch catalyst that has been taken from an industrial large-scale unit ope...
Unprecedented multi-stable spin crossover molecular material with two thermal memory channels.
Two in one: A new iron(II) complex with short alkyl substituents exhibits an unprecedented bimodal behavior governed by the coexistence of three phases: two structurally different low-spin phases and...
An Umpolung approach, in which a phosphorus ylide moiety was introduced to increase the electron density of the double bond, was developed to activate electron-deficient alkenes for reaction with elec...
A detailed mechanistic study of the hydroxylation of alkane CH bonds using H2 O2 by a family of mononuclear non heme iron catalysts with the formula [Fe(II) (CF3 SO3 )2 (L)] is described, in which...
News Articles
Lyme Research Alliance Awards $500,000 in Grants
With Lyme disease the fastest growing vector-borne illness in the nation, the urgency of advancing research is greater than ever before. Lyme Research Alliance is awarding half a million dollars to fu...
Another FDA 'breakthrough' designation: Synageva's sebelipase alfa
Synageva BioPharma started the trading week off by revealing to investors the firm gained the FDA's breakthrough therapy designation for sebelipase alfa (SBC-102) as a treatment for early onset lyso...
After raveges of flesh-eating bacteria, Aimee Copeland uses new bionic hands
Flesh-eating bacteria amputee Aimee Copeland now uses the latest technology in prosthetic hands to chop vegetables, pick up tiny items like Skittles, and comb and iron press her hair. (CNN)
USB12Shots.com Discusses the Possibility of B12 Shots for Weight Loss
NEW YORK, May 20, 2013 /PRNewswire-iReach/ -- It is no secret that Americans have an obesity problem. With more than one third being overweight or obese gyms and supplement companies are in line to ma...
RNA capable of catalyzing electron transfer on early Earth with iron's help
Read more about RNA capable of catalyzing electron transfer on early Earth with iron's help
Synageva BioPharma Corp. (Synageva) (NASDAQ:GEVA), a biopharmaceutical company developing therapeutic products for rare diseases, today announced that the U.S. Food and Dru...
FDA designates Synageva's sebelipase alfa as Breakthrough Therapy for early onset LAL Deficiency
Synageva BioPharma Corp., a biopharmaceutical company developing therapeutic products for rare diseases, today announced that the U.S. Food and Drug Administration granted Breakthrough Therapy designa...
TechAtlas Group Releases Innovative Chronic Kidney Disease Landscape Map
BOSTON, May 17, 2013 /PRNewswire/ -- TechAtlas Group has announced the release of the latest update for their competitive landscape map for the Chronic Kidney Disease (CKD) market. This particula...
Rockwell Medical Closes $40.3 Million Public Offering of Common Stock
WIXOM, MI -- (Marketwired) -- 05/20/13 -- Rockwell Medical, Inc. (NASDAQ: RMTI), a fully-integrated biopharmaceutical company targeting end-stage renal disease (ESRD) and chronic kidney disease (CKD)...
Rockwell Medical Presents PRIME Study Results at the 50th ERA-EDTA Meeting in Istanbul, Turkey
WIXOM, MI -- (Marketwired) -- 05/20/13 -- Rockwell Medical (NASDAQ: RMTI), a fully-integrated biopharmaceutical company targeting end-stage renal disease (ESRD) and chronic kidney disease (CKD) with...
Events
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Companies
Columbia Laboratories, Inc. is focused on developing products that utilize its novel bioadhesive drug delivery technologies to optimize drug delivery in a controlled, sustained ma...
TheAmerican Association of Clinical Endocrinologists (AACE)
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
Kamada is a public biopharmaceutical company (TASE: KMDA) developing, producing and marketing a line of specialty life-saving biopharmaceuticals. Licensed and marketed worldwide,...
Headquartered in Morrisville, North Carolina, TearScience® has pioneered devices that provide significant clinical improvement in the treatment of evaporative dry eye. Of the m...
Akebia Therapeutics is a discovery and development company focused on anemia and vascular disorders. Akebiaâs lead program, AKB-6548, an orally bioavailable HIF-prolyl hydrox...
AGTC is focused on the research and development of novel therapeutics for patients with unmet medical needs utilizing AGTCâs proprietary, non-pathogenic adeno-associat...
The American Association of Clinical Endocrinologists
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
Mission statement: The Alpha-1 Project will work with patients, academia, pharmaceutical and biotech companies, and public health organizations in the relentless pursuit of cures...
Iron Mountain Incorporated (NYSE: IRM) provides information management services that help organizations lower the costs, risks and inefficiencies of managing their physical and di...
The mission of the Alpha-1 Foundation is to provide the leadership and resources that will result in increased research, improved health, worldwide detection, and a cure for Alpha...
Clinical Trials
This study will evaluate the safety and effectiveness of treating patients with severe aplastic anemia (SAA) or myelopdysplastic syndrome (MDS) with both peripheral blood stem cells from a...
Low cobalamin (vitamin B12) levels are frequent in the elderly. Most often they reflect a mild metabolic abnormality without clinical symptoms (subclinical cobalamin deficiency). It is unc...
Trial of the Impact of Vitamin A on Maternal Mortality
Main objectives: To evaluate the impact of weekly vitamin A supplementation (VAS) to women of reproductive age (15-45 years) on maternal mortality in rural Ghana, and to compare this with...
Effects of Anemia Correction on Vascular and Monocyte Function in Renal Transplant Recipients
Correction of anaemia in renal transplant recipients by parenteral application of recombinant erythropoietin and if necessary iron will improve large artery function (endothelial function...
Iron Sucrose in Stage 3/4 Kidney Disease
One of the complications of late stage kidney disease is the development of a low red blood cell count (anaemia/low haemoglobin concentration). The Australian Commonwealth government limit...
Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization
Problems of compatibility between a mother and her child are frequent. The most well-known case can be illustrated by the fetomaternal blood group incompatibility (rhesus factor) which can...
Single-Dose Postpartum Vitamin A Supplementation of Mothers and Neonates
The ZVITAMBO PROJECT is testing whether giving mothers and infants a single large dose of vitamin A during the immediate post partum period will reduce: 1. Infant Mortality Can oral adm...
Alemtuzumab to Treat Severe Aplastic Anemia
This study will evaluate the safety and usefulness of a new immunosuppressive drug, alemtuzumab (Campath(Registered Trademark)), in patients with severe aplastic anemia (SAA). SAA is a rar...
Evaluation of the Safety of a Polyvalent Virus in Healthy Adults
This is a research study to evaluate the safety of a vaccine to protect people from HIV infection. Human Immunodeficiency Virus (HIV) is the cause of AIDS (Acquired Immune Deficiency Syndr...
Caffeine for Apnea of Prematurity (CAP)
At least 5 of every 1000 live-born babies are very premature and weigh only 500 to 1250 grams at birth. Approximately 30-40% of these high-risk infants either die or survive with lasting...
Videos
Anemia 1: Overview & Iron Deficiency Anemia
Description of three classifications of anemia, and an explanation of the pathophysiology of iron deficiency anemia. To be continued . . .
Medical and Biotech [MESH] Definitions
Iron-binding Proteins
Proteins that specifically bind to IRON.
Transferrin-binding Proteins
A class of carrier proteins that bind to TRANSFERRIN. Many strains of pathogenic bacteria utilize transferrin-binding proteins to acquire their supply of iron from serum.
Bacterial Transferrin Receptor Complex
A complex of proteins that forms a receptor for TRANSFERRIN in BACTERIA. Many pathogenic bacteria utilize the transferrin-binding complex to acquire their supply of iron from serum.
Iron-regulatory Proteins
Proteins that regulate cellular and organismal iron homeostasis. They play an important biological role by maintaining iron levels that are adequate for metabolic need, but below the toxicity threshold.
Iron Regulatory Protein 1
A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its RNA binding ability and its aconitate hydrolase activity are dependent upon availability of IRON.
