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Iron Deficiency Anemia - Biotech, Pharma and Life Science Channel

11:15 EDT 23rd April 2014 | BioPortfolio

PubMed Articles [2700 Associated PubMed Articles listed on BioPortfolio]

Bilateral femoral neck insufficiency fractures secondary to vitamin D deficiency and concurrent corticosteroid use-a case report.

We present a rare case of a 67-year-old Indian female who was found to have bilateral insufficiency of the neck of femur fractures secondary to osteomalacia from vitamin D deficiency, with her symptom...

Relationship between 25-hydroxyvitamin D concentrations, serum calcium, and parathyroid hormone in apparently healthy Syrian people.

Vitamin D deficiency (25-hydroxyvitamin D (25OHD)

Direct coupling of annexin A5 to VSOP yields small, protein-covered nanoprobes for MR imaging of apoptosis.

Annexin A5 (Anx) has been extensively used for imaging apoptosis by single-photon emission computed tomography, positron emission tomography, optical imaging and MRI. Recently we introduced ultrasmall...

Good's Syndrome, CVID, and Selective Antibody Deficiency in Patients with Chronic Rhinosinusitis.

Good's syndrome and common variable immune deficiency (CVID) are associated with chronic rhinosinusitis. Good's syndrome is characterized by hypogammaglobulinemia, B-cell depletion, variable defects i...

Prediction of carotenoids, cyanide and dry matter contents in fresh cassava root using NIRS and Hunter color techniques.

Efforts are currently underway to improve carotenoids content in cassava roots through conventional breeding as a strategy to reduce vitamin A deficiency. However, only few samples can be quantified e...

Multi-elemental analysis of ready-to-eat "baby leaf" vegetables using microwave digestion and high-resolution continuum source atomic absorption spectrometry.

The mineral content (phosphorous (P), potassium (K), sodium (Na), calcium (Ca), magnesium (Mg), iron (Fe), manganese (Mn), zinc (Zn) and copper (Cu)) of eight ready-to-eat baby leaf vegetables was det...

Influence of non-migratory metal-chelating active packaging film on food quality: Impact on physical and chemical stability of emulsions.

Previously, we developed a novel metal-chelating packaging film (PP-g-PAA) by grafting acrylic acid (AA) monomer from polypropylene (PP) film surface, and demonstrated its potential in controlling iro...

Colloidal iron(III) pyrophosphate particles.

Ferric pyrophosphate is a widely used material in the area of mineral fortification but its synthesis and properties in colloidal form are largely unknown. In this article, we report on the synthesis...

Intracellular performance of tailored nanoparticle tracers in magnetic particle imaging.

Magnetic Particle Imaging (MPI) is a quantitative mass-sensitive, tracer-based imaging technique, with potential applications in various cellular imaging applications. The spatial resolution of MPI, i...

Mechanisms of radical formation in beef and chicken meat during high pressure processing evaluated by electron spin resonance detection and the addition of antioxidants.

The generation of radicals during high pressure (HP) processing of beef loin and chicken breast was studied by spin trapping and electron spin resonance detection. The pressurization resulted in a hig...

News Articles [870 Associated News Articles listed on BioPortfolio]

Ligand to Participate in Three Upcoming Investor Conferences

Ligand Pharmaceuticals Incorporated (NASDAQ: LGND) announces that company executives are scheduled to participate in the following upcoming investor conferences:...

Chemotherapy Induced Anemia - Pipeline Review, H1 2014

Recently added to the BioPortfolio report store, Chemotherapy Induced Anemia - Pipeline Review, H1 2014 is a new report from Global Markets Direct published on 2014-03-30. This 60-page report is avai...

Renal Anemia - Pipeline Review, H1 2014

Recently added to the BioPortfolio report store, Renal Anemia - Pipeline Review, H1 2014 is a new report from Global Markets Direct published on 2014-03-30. This 115-page report is available in PDF f...

Former Iron Curtain still barrier for deer

The Iron Curtain was traced by an electrified barbed-wire fence that isolated the communist world from the West. It was an impenetrable Cold War barrier—and for some inhabitants of the Czech Republi...

Vitamin D Blog: Cavities in Kids?

(MedPage Today) -- Vitamin D deficiency in pregnancy may be tied to the child's future risk of dental cavities, a new study conducted in Canadian Aboriginals found.

Vitamin D deficiency in Scotland

Welsh and Sattar discourage population-wide vitamin D supplementation, referring to a linked research article in The BMJ.1 However, our northerly latitude and climate in Scotland changes the...

Ligand to Report First Quarter Results on May 7th

Ligand Pharmaceuticals Incorporated (NASDAQ:LGND) announced today plans to report first quarter 2014 financial results on May 7, 2014. Ligand’s President and CEO John Higgins, E...

Nephrologists Indicate that Improvement in Renal Anemia Parameters is One of the Top Three Efficacy Attributes for a New Hyperphosphatemia Treatment

BURLINGTON, Mass., April 22, 2014 /PRNewswire/ -- Decision Resources Group finds that reduction in mortality, reduction in serum phosphorus levels, followed by improvement in renal anemia paramet...

Dominion Diagnostics Chief Scientific Advisor Kenneth Blum, PhD Receives 2014 ASAM Medical-Scientific Program Committee Award for Best Scientific Abstract

NORTH KINGSTOWN, R.I., April 22, 2014 /PRNewswire/ -- Kenneth Blum, PhD, President and CEO of IGENE, LLC, has long been associated with leading drug monitoring laboratory Dominion Diagnostics in...

Agios amends follow-on

Agios Pharmaceuticals Inc. (NASDAQ:AGIO) said it now plans to sell 2 million shares in a follow-on underwritten by JPMorgan; Goldman Sachs; Cowen; and Leerink. If sold at Agios' close of $48.42 on Apr...

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Companies [31 Associated Companies listed on BioPortfolio]

AlphaNet, Inc.

Alpha-1 Antitrypsin Deficiency is one of North America’s most prevalent, potentially lethal hereditary disorders. Discovered in 1963, Alpha-1 can cause life-threatening lung...

Akebia Therapeutics, Inc.

Akebia Therapeutics is a discovery and development company focused on anemia and vascular disorders. Akebia’s lead program, AKB-6548, an orally bioavailable HIF-prolyl hydrox...

American Regent, Inc.

American Regent, Inc., a wholly owned subsidiary of Luitpold Pharmaceuticals, Inc. (a Daiichi Sankyo Group Company), headquartered in Shirley, NY, distributes over 80 pharmaceutic...

Iron Bridge Integration

Iron Bridge Integration (IBI) is a cloud-based healthcare software company headquartered in Pittsburgh, Pennsylvania. IBI’s cloud-based solutions simplify the complex exchang...

Sideris Pharmaceuticals, Inc.

Sideris Pharmaceuticals Inc. is a privately held biopharmaceutical company that is focused on development of therapeutics for the treatment of transfusion-related iron overload. T...

QOL Medical, LLC

QOL Medical, LLC, based in Vero Beach, is a specialty biopharmaceutical company focused on pediatric products for genetic and rare orphan diseases. QOL invests in clinical stage a...

bluebird bio, Inc.

bluebird bio is developing innovative gene therapies for severe genetic disorders. At the heart of bluebird bio’s product creation efforts is its broadly applicable gen...

Iron Mountain Incorporated

Iron Mountain Incorporated (NYSE: IRM) provides information management services that help organizations lower the costs, risks and inefficiencies of managing their physical and di...

Columbia Laboratories, Inc.

Columbia Laboratories, Inc. is focused on developing products that utilize its novel bioadhesive drug delivery technologies to optimize drug delivery in a controlled, sustained ma...

TheAmerican Association of Clinical Endocrinologists (AACE)

The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...

Clinical Trials [1148 Associated Clinical Trials listed on BioPortfolio]

A Study for Monthly Methoxy Polyethylene Glycol-Epoetin Beta Treatment in Patients With Chronic Renal Anaemia

This open-label single-arm study will evaluate the efficacy, safety and tolerability of methoxy polyethylene glycol epoetin beta on long-term maintenance of haemoglobin levels in patients...

FG-4592 (ASP1517) in the Treatment of Anemia in Chronic Kidney Disease Patients Not Requiring Dialysis

This study is conducted to treat anemia in patients with chronic kidney disease. Anemia is a reduced number of red blood cells or hemoglobin. Hemoglobin is important for the transport of o...

Safety and Efficacy Phase 2 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children

This is a phase II, open label, active-controlled, randomized safety and dose finding study of different MOD-4023 dose levels compared to daily r-hGH therapy in pre-pubertal growth hormone...

Chronic Pain and Vitamin D

Non-systematized chronic musculoskeletal pains are a frequent reason for consulting in general practice. The possible causes are numerous and sometimes nonspecific. In some cases, the etio...

A Pilot Study to Assess the Influence of Dietary Organic Acids on Iron Absorption.

Iron deficiency is the most common micronutrient deficiency in the world today, affecting more than 60% of the global population (www.who.int/nut/ida.htm). The two main strategies for the...

Sildenafil for Treatment of Priapism in Men With Sickle Cell Anemia

This research is being done to see if the drug sildenafil (Viagra) has an effect on the frequency of recurrent priapism and the quality of life in males with sickle cell disease.

Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelopdysplastic Syndrome

This study will evaluate the safety and effectiveness of treating patients with severe aplastic anemia (SAA) or myelopdysplastic syndrome (MDS) with both peripheral blood stem cells from a...

Intravenous Iron in Gynecologic Cancer Patients Receiving Chemotherapy

Can intravenous iron lower the rate of blood transfusion in gynecologic cancer patients receiving platinum based chemotherapy than oral iron?

Treatment of Menorrhagia in Women With Thrombocytopenia Using Platelets or Platelets and Hormones

This study will explore the role of oral contraceptive pills in managing uterine bleeding in women who have low blood platelet counts as a result of aplastic anemia. Oral contraceptive pil...

Thalidomide and Epoetin Alfa in Treating Anemia in Patients With Myelodysplastic Syndrome

RATIONALE: Thalidomide may stop or slow the growth of cancer cells. Epoetin alfa may stimulate red blood cell production. Combining thalidomide with epoetin alfa may improve anemia, decrea...

Medical and Biotech [MESH] Definitions

Anemia characterized by decreased or absent iron stores, low serum iron concentration, low transferrin saturation, and low hemoglobin concentration or hematocrit value. The erythrocytes are hypochromic and microcytic and the iron binding capacity is increased.

Iron or iron compounds used in foods or as food. Dietary iron is important in oxygen transport and the synthesis of the iron-porphyrin proteins hemoglobin, myoglobin, cytochromes, and cytochrome oxidase. Insufficient amounts of dietary iron can lead to iron-deficiency anemia.

Anemia characterized by a decrease in the ratio of the weight of hemoglobin to the volume of the erythrocyte, i.e., the mean corpuscular hemoglobin concentration is less than normal. The individual cells contain less hemoglobin than they could have under optimal conditions. Hypochromic anemia may be caused by iron deficiency from a low iron intake, diminished iron absorption, or excessive iron loss. It can also be caused by infections or other diseases, therapeutic drugs, lead poisoning, and other conditions. (Stedman, 25th ed; from Miale, Laboratory Medicine: Hematology, 6th ed, p393)

A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)

An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)

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