Juvenile Idiopathic Arthritis JIA - Biotech, Pharma and Life Science Channel
PubMed Articles
INTRODUCTION: Nonunion of femoral neck fractures frequently occurs in elderly patients. In patients with rheumatoid arthritis, reoperation rates after internal fixation of a displaced femoral neck fra...
Longidorus aetnaeus Roca, Lamberti, Agostinelli & Vinciguerra, 1986 is reported for the first time from Iran and Ajaria (Georgia). Morphological and morphometric data are provided for two Iranian and...
A population of Xiphinema macroacanthum Lamberti, Roca & Agostinelli, 1989 originating from olive orchards in Brindisi, Italy and containing both adults and all juvenile stages, is described and illus...
AIM. To review the results of implementing a protocol for following up patients with idiopathic intracranial hypertension (IICH) in a neuro-ophthalmological unit (NOU). PATIENTS AND METHODS. A review...
Is idiopathic recurrent pancreatitis attributed to small stones?
Idiopathic recurrent pancreatitis remains a clinical challenge. Intraductal ultrasonography in the management of idiopathic recurrent pancreatitis may be a new strategy for undetermined causes after i...
Chronic thromboembolic pulmonary hypertension (CTEPH) and idiopathic pulmonary hypertension (IPAH) share a similar clinical presentation, and a differential diagnosis requires a thorough workup. Once...
Objectives: The hypothesis of this study was that juvenile pubic symphysiodesis (JPS) results in pelvic changes that can be identified radiographically in adult dogs. Methods: The medical records at t...
Objective: To assess patients' acceptability of switching etanercept from the prefilled syringe to the autoinjection pen in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis patient...
Spiral colon impaction in juvenile alpacas: 12 cases (2006-2010).
Objective-To describe clinical signs and treatment outcomes for juvenile alpacas with spiral colon impaction (SCI). Design-Retrospective case series. Animals-12 juvenile (< 6 months old) camelids with...
Case Description-A 4-year-old sexually intact male mixed-breed dog was evaluated because of clinical signs of acute-onset pelvic limb ataxia, rapidly progressing to paraplegia with severe spinal hyper...
News Articles
[RuiYi] enlists the help of [Genor] to develop its RA candidate in China
[RuiYi Inc.] (formerly Anaphore) has signed on fellow antibody firm [Genor Biopharma Co. Ltd.] to help develop and exclusively commercialize in China its preclinical anti-interleukin-6 (IL-6) monoclon...
New study shows UCB's Neupro reduces NSBP in RLS patient
Leading Belgian drugmaker UCB (Euronext Brussels: UCB) today (May 17) announced data from a double-blind, placebo-controlled study that found that Neupro (rotigotine transdermal system) reduced total...
Neovacs moving forward in rheumatoid arthritis, say analysts
French biotech firm Neovacs (Alternext Paris: ALNEV) intends to initiate a Phase IIb trial with its lead product TNFalpha-Kinoid in rheumatoid arthritis (RA). The strategy is designed to maintain mome...
FDA approves Novartis juvenile arthritis drug
The FDA has approved Novartis’ drug Ilaris (canakinumab) for the treatment of active systemic juvenile idiopathic arthritis (SJIA) in patients aged two years and older. Ilaris is the first interleuk...
Edison Investment - Neovacs - Moving forward in rheumatoid arthritis
Neovacs intends to initiate a Phase IIb trial with its lead product TNFα-Kinoid in rheumatoid arthritis (RA). The strategy is designed to maintain momentum of the programme while it seeks a pa...
Belgium's Galapagos says on track to meet 2013 guidance
BRUSSELS, May 17 (Reuters) - Galapagos, the Belgian developer of drugs to fight autoimmune diseases such as lupus and rheumatoid arthritis, said it was on track to meet its full-year revenue guidance...
Research reveals vitamin C does not reduce urate levels in gout patients
Despite previous studies touting its benefit in moderating gout risk, new research reveals that vitamin C, also known ascorbic acid, does not reduce uric acid (urate) levels to a clinically significan...
Allsup Observes May as Arthritis Awareness Month
Arthritis affects more than 21 million Americans; Allsup representatives can assist individuals with arthritis in applying for Social Security Disability Insurance benefits. Belleville, Ill. (PRWEB) M...
Data Show Promise of PRM-151 in Diseases Involving Fibrosis Promedior, Inc., a clinical stage biotechnology company developing novel biologic therapeutics for th...
Inmates With Mental Health Problems Reported High Rates Of Sexual Victimization In 2011-12
WASHINGTON, May 16, 2013 /PRNewswire-USNewswire/ -- Prison and jail inmates identified with mental health problems reported higher rates of inmate-on-inmate sexual victimization than inmates without a...
Events
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Companies
Based in Gainesville, Fla., Exactech develops and markets orthopaedic implant devices, related surgical instruments and biologic materials and services to hospitals and physicians...
Zalicus focuses its internal drug development efforts on pain and immuno-inflammatory diseases. Our pipeline for pain includes Exalgo⢠(hydromorphone HCl) extended-release ta...
The International Society for Interferon and Cytokine Research (ISICR), based in Bethesda, Md., is a non-profit organization devoted to interferon, cytokine and chemokine r...
America Stem Cell is a privately held biotechnology company based in San Antonio, TX, with offices in San Diego, CA, and is dedicated to the development and commercialization of s...
LW Robbins (www.lwra.com) is a full service direct response fundraising agency devoted to helping nonprofit organizations acquire and cultivate loyal donors, and raise more...
Based in Gainesville, Fla., Exactech develops and markets orthopaedic implant devices, related surgical instruments and biologic materials and services to hospitals and physicians...
Moximed® Inc is dedicated to improving the standard of care for patients with osteoarthritis. OA, the most common form of arthritis, leads to a breakdown of the jointâs ca...
Ignyta, Inc., located in San Diego, California, is a personalized medicine company developing revolutionary new products and services to customize diagnosis and treatment of patie...
Plexxikon is a leader in the structure-guided discovery and development of novel small molecule pharmaceuticals to treat human disease. The companyâs lead compound, PLX4032,...
Entelos, Inc. (www.entelos.com) is a life sciences company applying next-generation predictive technologies across multiple markets in R&D, healthcare and finance to dramat...
Clinical Trials
Pilot Trial to Assess Effect of CNI Conversion of Efalizumab on T Reg Cells
The purpose of this pilot trial is to determine whether a conversion from calcineurin inhibitors (CNI) and mycophenolate mofetil (MMF) to a regimen consisting of efalizumab and sirolimus i...
A Study of Epirubicin With Estramustine Phosphate and Celecoxib for the Treatment of Prostate Cancer
The purpose of this clinical trial is to find out the effect of epirubicin with estramustine phosphate and celecoxib on PSA and objective response in patients with hormone resistant prosta...
The objective of the study is to identify and validate predictive markers of infliximab responsiveness in RA patients by 2 approaches: i) measuring biochemical, immunological and bone mark...
The objective of the study is to identify and validate predictive markers of anakinra responsiveness in RA patients by a transcriptomic approach. Patients with active RA (ACR criteria) we...
The purpose of this study is to monitor the performance of the DePuy PROXIMA™ hip in the treatment of patients with hip joint disease requiring a total hip replacement. Patients who ente...
Alleviated Positioning for Small Macular Holes
Rational of the study: There are arguments to think that the closure of macular holes can be obtained without a strict positioning under certain conditions, i.e. hole size ≤ 400 µm, if...
Although SLE and RA are correlated with genetic predisposing factors such as human leukocyte antigen (HLA) class II, both diseases and other genetic factors might have contributed to the d...
Treatment of Idiopathic Pulmonary Fibrosis With Thalidomide
The goal of this study is to determine whether thalidomide can stop the progression of fibrosis in IPF. The primary objective of this study is to determine the safety, feasibility and eff...
Enterra Therapy Clinical Study (Gastric Stimulation for Gastroparesis)
This study is to evaluate the safety and effectiveness of gastric stimulation in the reduction of nausea and vomiting in patients with gastroparesis using an approved Humanitarian device....
Develop Biomarkers for Assessing RA Joint Erosion
With the current therapeutic focus in rheumatoid arthritis (RA) shifting from symptom control to actual disease modification there is a growing demand for more objective and sensitive ways...
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Medical and Biotech [MESH] Definitions
Leukocyte L1 Antigen Complex
A member of the S-100 protein family that is present at high levels in the blood and interstitial fluid in several infectious, inflammatory, and malignant disorders, including rheumatoid arthritis, inflammatory bowel disease, and cystic fibrosis. It is a complex of a light chain (CALGRANULIN A) and a heavy chain (CALGRANULIN B). L1 binds calcium through an EF-hand motif, and has been shown to possess antimicrobial activity.
Retinoschisis
A vitreoretinal dystrophy characterized by splitting of the neuroretinal layers. It occurs in two forms: degenerative retinoschisis and X chromosome-linked juvenile retinoschisis.
Mycoplasma Bovis
A species of gram-negative bacteria causing MASTITIS; ARTHRITIS; and RESPIRATORY TRACT DISEASES in CATTLE.
Mycoplasma Hyosynoviae
A species of gram-negative bacteria isolated from the SYNOVIAL FLUID; LYMPH NODES; and MUCOUS MEMBRANE secretions in diseased SWINE. It causes nonsuppurative ARTHRITIS.
Mycoplasma Salivarium
A species of gram-negative bacteria strongly implicated in oral infection, PERIODONTAL DISEASES, eye and ear disorders, and SEPTIC ARTHRITIS.