Kidney Transplantation - Biotech, Pharma and Life Science Channel
PubMed Articles
Enhancement of wound closure in diabetic mice by ex vivo expanded cord blood CD34(+) cells.
Diabetes can impair wound closure, which can give rise to major clinical problems. Most treatments for wound repair in diabetes remain ineffective. This study aimed to investigate the influence on wou...
Abelmoschus manihot (L.) medic (AM) is a natural medicinal plant used for the treatment of inflammatory diseases in China. Huangkui capsule (HKC), an extract from AM, has been proved clinically effect...
Suture-free amniotic membrane transplantation.
Amniotic membrane transplantation has been used very successfully in ophthalmology since the 1940s for treatment of surface disorders. Over the course of the years the indications for use have been co...
Early postoperative complications after orthotopic liver transplantation (OLT) are a common problem in intensive care medicine. Adequate assessment of initial graft function remains difficult, however...
Patients with both chronic kidney disease (CKD) and diabetes mellitus (DM) are at increased risk for thrombotic events compared to those with one abnormality alone. Whether this can be attributed to c...
Secondary polycythemia with increased production of erythropoietin (EPO) is known to occur in kidney diseases such as hydronephrosis and cystic disease, but the mechanism remains unclear. We report an...
Peginesatide as a new approach for treating anemia of CKD patient: is it like a falling star?
Any scientific innovation needs to translate into a significant benefit. Peginesatide is noninferior to other erythropoiesis stimulating agents (ESAs) in terms of efficacy, and it shares the advantage...
Current and future therapies for hepatitis C virus infection.
BACKGROUND: SBR759, an iron (III)-based oral phosphate binder, was developed for the treatment of hyperphosphataemia in chronic kidney disease stage V patients receiving maintenance renal replacement...
Urinary and glomerular podocytes in patients with chronic kidney diseases.
BACKGROUNDS: Podocytes are highly differentiated epithelial cells involved in glomerular filtration. This study determines the clinical and histological significance of podocyte detachment and excreti...
News Articles
ROCKVILLE, Md., May 20, 2013 /PRNewswire/ -- Neuralstem, Inc. (NYSE MKT: CUR) today reported that Eva Feldman, MD, PhD, principal investigator, presented updated Phase I data from its...
New Drug Combinations Block Kidney Cancer in Culture and Mouse Models
Drugs that block the activity of the enzyme Stearoyl-CoA desaturase-1 repress the growth of kidney cancer cells in culture and...
TechAtlas Group Releases Innovative Chronic Kidney Disease Landscape Map
BOSTON, May 17, 2013 /PRNewswire/ -- TechAtlas Group has announced the release of the latest update for their competitive landscape map for the Chronic Kidney Disease (CKD) market. This particula...
HORSHOLM, Denmark, May 20, 2013 /PRNewswire/ -- Veloxis Pharmaceuticals A/S (OMX: VELO) today announced that data from the STRATO study demonstrates the potential for LCP-Tacro™ to improve...
In Patients With Kidney Disease, LDL Cholesterol Is A Poor Marker Of Heart Health
Other measures are needed to assess patients' cardiovascular risks Among patients with chronic kidney disease, those with very low kidney function had a higher risk of having a heart attack than...
The Polycystic Liver: Webinar & Talk
Hamilton, Canada, May 18, 2013 --(PR.com)-- On May 26, the Hamilton Chapter of the PKD Foundation of Canada will host a webinar by Dr. Marie Hogan of the Mayo Clinic in Rochester, MN, followed by a t...
Public offering nets $18.8mm for [Cyclacel]
[Cyclacel Pharmaceuticals Inc.] (mainly cancer therapies; also has projects for kidney disease, diabetes, and HIV/AIDS) netted $18.8mm through public offering of 6.67mm common shares at $3 each. Proce...
[Rockwell Medical] nets $38mm through FOPO
[Rockwell Medical Inc.] (end-stage renal and chronic kidney disease treatments) has netted $38mm through the follow-on public offering of 13.2mm common shares (including the overallotment) at $3.05. T...
Lab Notes: Cell Therapy May Rescue Veins in CKD
(MedPage Today) -- An intravenous infusion of endothelial cells improved vascular function in a mouse model of chronic kidney disease, researchers said. Also this week: another reason not to tailgate...
Researchers Test Implementation of WHO Hand Hygiene Improvement Strategy in Critical Care Units
To determine hand hygiene compliance before and after an intervention campaign in critical care units, Mazi, et al. (2013) conducted their study in the intensive care unit (ICU), neonatal intensive ca...
Events
Diabetes: Secondary Complications, Regulation and Innovation Conference
SMi is very proud to present our 11th conference focusing on Diabetes and metabolic disorders taking place on 1st and 2nd Oct 2013, London.
Companies
Loma Linda University Medical Center
Loma Linda University Medical Center (LLUMC), a Seventh-Day Adventist institution, is among the largest private medical educational centers in the United States and the only one in inland Southern...
Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...
Defymed is a spin -off of the “Centre Europeen d’etude du Diabete” (CeeD) which has been working on the conception of a bio-artificial pancreas since 1996. This work was ca...
Opsona is a leading immunology drug development company, focused on novel therapeutic approaches to key targets of the innate immune system associated with a wide range of majo...
Tissue Regeneration Technologies, LLC
TRT is an international medical device company established to develop, manufacture and sell SoftWaveTM acoustical pressure pulse devices to treat various conditions poorly served...
Global Mission Statement: Committed to education, prevention, awareness, and access, the Shad Ireland Foundation is an international non-profit organization that is actively explo...
RTI Biologics Inc. [OBJECT OMITTED]
RTI Biologics Inc. is a leading provider of sterile biologic implants for surgeries around the world with a commitment to advancing science, safety and innovation. RTI prep...
American Renal Associates LLC (âARAâ) is the operating subsidiary of American Renal Holdings, Inc. and is a leading owner and provider of outpatient kidney dialysis cent...
Baxter International Inc. and Takeda Pharmaceutical Company Limited
Baxter International Inc. (NYSE:Â BAX), through its subsidiaries, develops, manufactures and markets products that save and sustain the lives of people with hemophilia, immune d...
New Lung Associates is a pulmonary group of physicians leading the Lung Transplant Program and the Adult Cystic Fibrosis Program at Tampa General Hospital, a 988-bed acute care ho...
Clinical Trials
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Sarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and combining chemotherapy with periphe...
This randomized phase II trial is studying how well giving tacrolimus and mycophenolate mofetil (MMF) together with or without sirolimus works in preventing acute graft-versus-host disease...
Erlotinib and Sirolimus for the Treatment of Metastatic Renal Cell Carcinoma
The purpose of this study is to test the safety and efficacy of the combination of erlotinib hydrochloride (Tarceva™) and sirolimus (Rapamune™) in the treatment of patients with metast...
This study will evaluate the safety and effectiveness of treating patients with severe aplastic anemia (SAA) or myelopdysplastic syndrome (MDS) with both peripheral blood stem cells from a...
The investigators hypothesize that a calcineurin inhibitor-free, steroid-free, co-stimulatory blockade-based immunosuppressive regimen, in combination with a GLP-1 agonist, will reduce the...
Intervention to Motivate Teens to be a Designated Organ Donor on Driver's License
This study will test the effectiveness of a multimedia campaign to educate ethnic minority teens about the choice to become a designated organ donor on their first driver's license.
A Study in Patients With Diabetic Kidney Disease
The purpose of this study is to determine if LY2382770 is safe and effective at protecting kidney function in patients with kidney disease due to diabetes.
RATIONALE: Drugs used in chemotherapy, such as azacitidine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Interfe...
Islet Transplantation in Type 1 Diabetic Patients
Our hypothesis is that a successful clinical islet transplant program can be established at the University of Wisconsin using a steroid -free, sirolimus- and low dose tacrolimus - based im...
This pilot study is to assess whether using CytoGam® in combination with ganciclovir is more effective in reducing the CMV viral load over time, as compared to standard treatment with IV...
Videos
Pediatric Kidney Transplant - Dr. Pippi Salle
Surgical video of a pediatric kidney transplant. Performed by Dr. Pippi Salle (SickKids Hospital). © 2012, OR Media Inc.
Medical and Biotech [MESH] Definitions
Stem Cell Transplantation
The transfer of STEM CELLS from one individual to another within the same species (TRANSPLANTATION, HOMOLOGOUS) or between species (XENOTRANSPLANTATION), or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). The source and location of the stem cells determines their potency or pluripotency to differentiate into various cell types.
Receptor, Epha1
The founding member of the EPH FAMILY RECEPTORS. It was first cloned from an erythropoietin-producing human hepatocellular carcinoma cell line and is highly conserved among many mammalian species. Overproduction of the EphA1 receptor is associated with tumors and tumor cells of epithelial origin. It is also expressed at high levels in LIVER; LUNG; and KIDNEY; which is in contrast to many other members of the Eph receptor that are found primarily in tissues of the nervous system.
Cord Blood Stem Cell Transplantation
Transplantation of STEM CELLS collected from the fetal blood remaining in the UMBILICAL CORD and the PLACENTA after delivery. Included are the HEMATOPOIETIC STEM CELLS.
Peripheral Blood Stem Cell Transplantation
Transplantation of stem cells collected from the peripheral blood. It is a less invasive alternative to direct marrow harvesting of hematopoietic stem cells. Enrichment of stem cells in peripheral blood can be achieved by inducing mobilization of stem cells from the BONE MARROW.
Receptor, Ephb3
An eph family receptor found in a number of tissues including BRAIN; LUNG; KIDNEY; PANCREAS; INTESTINE; and HEART. During embryogenesis EphB3 receptor is expressed at high levels in the brain.
