Langerhans' Cell Histiocytosis - Biotech, Pharma and Life Science Channel
PubMed Articles
Accumulating evidence has shown that microRNAs are involved in multiple processes in cancer development and progression. Recently, miR-22 has been identified as a tumor-suppressing microRNA in many hu...
Hypermethylation and prognostic implication of Syk gene in human colorectal cancer.
The study was aimed to investigate the relationship between hypermethylation of Syk gene and clinicopathological characteristics and long-term outcomes in colorectal cancer. The effect of Syk on cell...
PTPN4 negatively regulates CrkI in human cell lines.
PTPN4 is a widely expressed non-receptor protein tyrosine phosphatase. Although its overexpression inhibits cell growth, the proteins with which it interacts to regulate cell growth are unknown. In th...
A crucial role for Lyn in TIMP-1 erythroid cell survival signalling pathway.
TIMP-1, a well-known MMP inhibitor, displays other biological activities such as cell survival, proliferation and differentiation in hematopoietic cells. In this report, we investigated the role of th...
Modeling the effect of cell division on genetic oscillators.
Many genetic oscillators (circadian clocks, synthetic oscillators) continue to oscillate across the cell division cycle. Since cell divisions create discontinuities in the dynamics of genetic oscillat...
Trichinella: What is going on during nurse cell formation?
Recent molecular studies have revealed that many genes are mobilized during nurse cell formation, including those involved in activation and proliferation of satellite cells, dedifferentiation, cell c...
Trypanosoma cruzi is a protozoan that causes Chagas' disease, a neglected infectious illness that affects millions of people, mostly in the Latin America. Here, the cell surface subproteome of the T....
Oxidative stress has been suggested as a potential contributor to the development of diabetic complications. In this study, we investigated the protective effect of a strong antioxidant copper complex...
Nonylphenol (NP), a representative endocrine disruptor, interferes with reproductive function in aquatic organisms and animals. Although many previous studies have focused on apoptotic cell death by N...
Recent clinical observations and experimental studies of our group indicate that macrophage migration inhibitory factor (MIF) may contribute to tumor progression in head and neck squamous cell carcino...
News Articles
Dr. Babak Larian, Otolaryngologist in Beverly Hills, says that radiotherapy may not be a helpful treatment option for patients experiencing early-stage parotid acinic cell cancer. Beverly Hills, CA (P...
BioRestorative signs consulting agreement with Dexterity for stem cell therapy device
BioRestorative Therapies (BRT) has signed a consulting agreement with Dexterity, to develop and manufacture BRT's proprietary therapeutic delivery device for its intervertebral disc stem cell therapy...
Germany's G-BA issues final assessment for Cell Thera's Pixuvri
USA-based Cell Therapeutics (Nasdaq: CTIC) says that Germany's Federal Joint Committee (G-BA) has issued its final benefit assessment report for Pixuvri (pixantrone), which is indicated as a monothera...
Maryland Stem Cell Research Commission Funds 31 New Research Proposals in FY 2013
COLUMBIA, Md., May 21, 2013 /PRNewswire/ -- The Maryland Stem Cell Research Commission (Commission) has completed its review of the 171 applications received in response to its FY 2013 Requests f...
Cell Therapy Catapult releases preclinical database
Cell Therapy Catapult releases preclinical database
Merck Millipore, PharmaCell to Optimize Cell Harvesting Using Bioreactor Technology
The project is expected to deliver scalable expansion and harvesting devices, validation methods and associated protocols for the production of large-scale stem cell therapies.
Confirmed: Primary endpoint of significantly improving overall survival not met Merck Serono, a division of Merck, Darmstadt, Germany, today announced detailed results from the randomized Phase III ST...
During CA Pertussis Outbreak, Whole-Cell Vaccine More Effective Than Acellular Vaccine
Whole-cell pertussis vaccines were more effective at protecting against pertussis than acellular pertussis vaccines during a large recent outbreak, according to a new Kaiser Permanente study published...
EMD Millipore, PharmaCell In Cell Development Pact
Will use bioreactor technology for large-scale production
Single-cell transfection tool enables added control for biological studies
(Northwestern University) Northwestern researchers have developed a novel tool for single-cell transfection, in which they deliver molecules into targeted cells through temporary nanopores in the cell...
Events
Select Biosciences' 4th annual Single Cell Analysis Summit 2013 will build on the overwhelming success of the previous Single Cell events.
SELECTBIO CellTech2014 will feature an integrated program of tracks designed to fully describe the latest trends in analysis of cells, cell-based assays, and high-content phenotypic assays.
Cell Culture World Congress USA
North America’s commercial cell culture event
Advancing cord blood banking & therapeutics
Stem Cells & Regenerative Medicine Congress
North America’s commercial stem cells event
Stem Cells & Cell Therapy Summit
Select Biosciences' Stem Cells & Cell Therapy Summit is focused on providing an up-to-date expansive view of the current marketplace
Oxford Global is proud to present the Biopharma Asia Series taking place on 24th & 25th September 2013 in Singapore.
2nd Annual Cell Culture & Bioprocessing Congress 2013
175 delegates representing leading biotech companies, global pharma organisations and internationally renowned academic institutions
th Annual Next Generation Sequencing Congress 2013
Over 400 Next Generation Sequencing, Genomics, Epigenetics, Genetics, Metagenomics experts from UK, Europe and USA
Companies
Auxogyn is a privately held medical technology company focused on advancing women's reproductive health by applying its novel scientific and clinical knowledge of early human developmental biology to...
OncoMed Pharmaceuticals is a clinical-stage company that discovers and develops novel therapeutics targeting cancer stem cells, the cells believed to be capable of driving tumor growth, recurrence and...
GL Rapha have been developing various ranges of pharmaceutical technologies specially focusing on Bio-pharmaceuticals such as recombinant proteins, synthetic peptides, and DDS bio similar based on t...
Plasticell is a pioneering biotechnology company that specialises in the differentiation of stem cells to obtain cell types for a range of biomedical applications. Founded in 2002, Plasticell has as...
Verastem, Inc. is a private biopharmaceutical company focused on discovering and developing novel drugs that selectively target cancer stem cells. Cancer stem cells are an underly...
Cell Medica is a clinical stage cellular therapeutics company engaged in the development and delivery of cellular immunotherapy treatment strategies for infectious disease and can...
Etubics Corporation, based in Seattle, Wash., is a clinical stage bio-pharmaceutical company, which has developed a proprietary platform technology consisting of a next generation...
Advanced Cell Technology, Inc.
Advanced Cell Technology, Inc. is a biotechnology company applying cellular technology in the field of regenerative medicine. For more information, visit http://www.advancedcell.c...
AmStem Inc. is a corporation registered in the State of Nevada with offices in San Francisco, California and Seoul, Korea. The company is a world leader in the area of stem cell r...
The International Society for Interferon and Cytokine Research (ISICR), based in Bethesda, Md., is a non-profit organization devoted to interferon, cytokine and chemokine r...
Clinical Trials
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Sarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and combining chemotherapy with periphe...
Imiquimod Cream in Treating Patients With Basal Cell Skin Cancer
RATIONALE: Biological therapies, such as imiquimod cream, work in different ways to stimulate the immune system and stop tumor cells from growing. PURPOSE: This randomized phase I trial i...
Cell Lines From High-Risk Breast Tissue
Background: - Many risk factors for breast cancer have been identified, including family history, endocrine background, changes in breast tissue, cancer in one breast, radiation...
Erlotinib and Sirolimus for the Treatment of Metastatic Renal Cell Carcinoma
The purpose of this study is to test the safety and efficacy of the combination of erlotinib hydrochloride (Tarceva™) and sirolimus (Rapamune™) in the treatment of patients with metast...
This randomized phase II trial is studying how well giving tacrolimus and mycophenolate mofetil (MMF) together with or without sirolimus works in preventing acute graft-versus-host disease...
The investigators hypothesize that a calcineurin inhibitor-free, steroid-free, co-stimulatory blockade-based immunosuppressive regimen, in combination with a GLP-1 agonist, will reduce the...
Stem Cell Collection With Ofatumumab
The goal of this clinical research study is to learn if it is possible to collect stem cells after ofatumumab and chemotherapy treatment. This study will also evaluate side-effects, number...
A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)
The main purpose of the study is to evaluate the efficacy and safety of the study drug known as prasugrel for the reduction of Vaso-Occlusive Crisis events in pediatric participants with s...
Study of OSI-774 (Tarceva) in Previously Untreated Elderly Lung Cancer Patients
The primary purpose of this study is to determine whether the drug OSI-774 is less toxic and potentially as good as or better than standard chemotherapy drugs, when given to subjects with...
Vemurafenib, Cetuximab, and Irinotecan in Advanced Solid Cancers
The goal of this clinical research study is to find the highest tolerable dose of vemurafenib that can be given in combination with cetuximab and irinotecan to patients with advanced cance...
Videos
LCH 101 Part 1 of 7
Learn about Langerhans Cell Histiocytosis (LCH) in this 7 part series presented by Dr. Ken McClain of Texas Children's Cancer Center. Part 1 Introduction & c...
Medical and Biotech [MESH] Definitions
Chromosomes, Plant
Complex nucleoprotein structures which contain the genomic DNA and are part of the CELL NUCLEUS of PLANTS.
Spectral Karyotyping
The simultaneous identification of all chromosomes from a cell by fluorescence in situ hybridization (IN SITU HYBRIDIZATION, FLUORESCENCE) with chromosome-specific florescent probes that are discerned by their different emission spectra.
Chromosomes, Mammalian
Complex nucleoprotein structures which contain the genomic DNA and are part of the CELL NUCLEUS of MAMMALS.
Stem Cell Transplantation
The transfer of STEM CELLS from one individual to another within the same species (TRANSPLANTATION, HOMOLOGOUS) or between species (XENOTRANSPLANTATION), or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). The source and location of the stem cells determines their potency or pluripotency to differentiate into various cell types.
Periplasmic Proteins
Proteins found in the PERIPLASM of organisms with cell walls.
