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Laryngeal Disorders - Biotech, Pharma and Life Science Channel

04:43 EDT 25th April 2014 | BioPortfolio

PubMed Articles [4068 Associated PubMed Articles listed on BioPortfolio]

Metabolomics approach in allergic and rheumatic diseases.

Metabolomics is the analysis of the concentration profiles of low molecular weight compounds present in biological fluids. Metabolites are nonpeptide molecules representing the end products of cellula...

Cross-cultural aspects of anxiety disorders.

A person's cultural background influences the experience and expression of emotions. In reviewing the recent literature on cross-cultural aspects of anxiety disorders, we identified some culturally re...

Adjustment disorder: new developments.

Adjustment disorders (ADs) have been included in the psychiatric classifications since 1952 although their name has changed over time. In DSM 5 they have been classified under the trauma and stress re...

Surgical salvage of recurrent cancer of the head and neck.

The therapeutic options and prognosis for recurrent squamous cell carcinoma of the upper aerodigestive tract vary greatly depending on site, extent of disease, and previous treatment. Surgical salvage...

Influence of dietary pattern, physical activity, and I148M PNPLA3 on steatosis severity in at-risk adolescents.

Evidence relating dietary patterns to obesity and related disorders such as non-alcoholic fatty liver disease (NAFLD) is limited in pediatric age. Aim of this study was to analyze the association betw...

FTO and Obesity: Mechanisms of Association.

The Fat mass and obesity associated (FTO) gene is a newly identified genetic factor for obesity. However, the exact molecular mechanisms responsible for the effect of FTO on obesity remain largely unk...

Adiposopathy, "Sick Fat," Ockham's Razor, and Resolution of the Obesity Paradox.

Among lean populations, cardiovascular disease (CVD) is rare. Among those with increased adiposity, CVD is the commonest cause of worldwide death. The "obesity paradox" describes seemingly contrary re...

Flavonoids in modulation of cell survival signalling pathways.

Flavonoids, a family of polyphenols, generally found in various fruits and vegetables, as well as in many plant beverages such as tea, pomegranate juice, raspberry, blueberries, and red wine. Recently...

High frequency of rare variants with a moderate-to-high predicted biological effect in protocadherin genes of extremely obese.

Relatively rare variants with a moderate-to-high biological effect may contribute to the genetic predisposition of common disorders. To investigate this for obesity, we performed exome sequencing for...

Five-factor model personality domains in the prediction of Axis II personality disorders: An exploratory study in late adulthood women non-clinical sample.

Relationships between Axis II personality disorders (DSM-IV) and the five-factor model were explored in a non-clinical sample of late adulthood women. The sample consists of 90 women (M = 72.29 ...

News Articles [2117 Associated News Articles listed on BioPortfolio]

Boehringer, Hydra Biosciences to develop small-molecule inhibitors to treat CNS disorders

German pharmaceutical firm Boehringer Ingelheim has entered into a worldwide collaboration with Hydra Biosciences, a US-based firm in the field of Transient Receptor Potential (TRP) channel modulation...

Reduced exposure to microbes triggers chronic inflammation

The greater prevalence of asthma, allergies and other chronic inflammatory disorders among people of lower socioeconomic status might be due in part to their reduced exposure to the microbes that thri...

Baxter to Present at the Deutsche Bank 39th Annual Health Care Conference

Baxter International Inc. (NYSE: BAX) announced today that it will present at the Deutsche Bank 39th Annual Health Care Conference on Wednesday, May 7, 2014 at 3:10 p.m. (CT)....

Mount Sinai Researchers Identify Genetic Alterations in Shared Biological Pathways as Major Risk Factor for Autism Spectrum Disorder

New study finds substantial proportion of risk for developing autism spectrum disorders resides in genes that are part of specific, interconnected biological pathways New York, NY (PRWEB) April 24, 20...

Vanda Pharmaceuticals to Announce First Quarter 2014 Financial Results on May 8, 2014

WASHINGTON, April 24, 2014 /PRNewswire/ -- Vanda Pharmaceuticals Inc. (Vanda) (NASDAQ: VNDA), a biopharmaceutical company focused on the development and commercialization of products for the trea...

Hydra, Boehringer in CNS deal

Hydra Biosciences Inc. (Cambridge, Mass.) partnered with Boehringer Ingelheim GmbH (Ingelheim, Germany) to develop small molecule inhibitors against transient receptor potential cation channel subfami...

FDA holding meeting for inborn errors of metabolism

FDA will hold a public meeting on June 10 to discuss neurological manifestations of inborn errors of metabolism, such as lysosomal storage disorders Gaucher's and Niemann-Pick disease. The meeting is...

Genetic alterations in shared biological pathways as major risk factor for ASD

A substantial proportion of risk for developing autism spectrum disorders (ASD), resides in genes that are part of specific, interconnected biological pathways, according to researchers from the Icahn...

Drexel University Online Launches Certificate of Advanced Study in Integrative Addiction Therapies

Drexel University Online, a premier provider of Internet-based higher education, and the Drexel University College of Nursing and Health Professions are pleased to announce the creation of the Certifi...

Advanced Cell Technology’s Chief Scientific Officer Dr. Robert Lanza Named One of TIME Magazine’s 100 Most Influential People in the World

Dr. Lanza and the other TIME 100 will be honored at a Gala Event on Tuesday April 29, 2014 Advanced Cell Technology, Inc. ("ACT"; OTCBB: ACTC), a leader in the field of...

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Companies [241 Associated Companies listed on BioPortfolio]

Pulmonx

Pulmonx, based in Redwood City, CA, is focused on developing and marketing minimally-invasive medical devices and technologies for the diagnosis and treatment of pulmonary disorde...

TransTech Pharma, LLC

TransTech Pharma is a privately held, company focused on the discovery, development, and commercialization of human therapeutics to fill unmet medical needs. The Company’s hi...

AlphaNet, Inc.

Alpha-1 Antitrypsin Deficiency is one of North America’s most prevalent, potentially lethal hereditary disorders. Discovered in 1963, Alpha-1 can cause life-threatening lung...

Cytox Limited

Cytox is a UK company developing products and services for neurodegenerative disorders. The company provides biomarker services to pharmaceutical industry clients conducting clinical trials with drugs...

rEVO Biologics Inc.

rEVO Biologics Inc. (www.revobiologics.com) is a commercial-stage biopharmaceutical company focused on the development and commercialization of specialty therapeutics to address...

WestBridge

With locations in Florida, New Hampshire and Massachusetts, WestBridge, Inc. has been supporting the recovery of individuals and families that experience co-occurring mental illne...

Akebia Therapeutics, Inc.

Akebia Therapeutics is a discovery and development company focused on anemia and vascular disorders. Akebia’s lead program, AKB-6548, an orally bioavailable HIF-prolyl hydrox...

SynapDx Corp.

SynapDx is a private company providing laboratory diagnostics to physicians who suspect children of developmental disorders, with the initial goal of enabling earlier detec...

Eating Recovery Center

Eating Recovery Center is an international center providing comprehensive treatment for anorexia, bulimia, EDNOS and binge eating disorder. Under the leadership of Drs. Kenneth We...

Lundbeck LLC

Lundbeck in the U.S., headquartered in Deerfield, Illinois, is a wholly-owned subsidiary of H. Lundbeck A/S in Denmark. Lundbeck is committed to accelerating advances in brain dis...

Clinical Trials [1268 Associated Clinical Trials listed on BioPortfolio]

Comparative Efficacy of Phenylbutyrate vs. Benzoate in Urea Cycle Disorders

The investigators will study and compare how effectively two drugs (sodium phenylbutyrate and sodium benzoate) help excrete nitrogen in urea cycle disorders patients. Subject participation...

Guanfacine in Children With Tic Disorders

The goal of this pilot study is to obtain preliminary information on the tolerability and efficacy of extended release guanfacine (trade name Intuniv) in children with Tourette Disorder (T...

A Randomized Clinical Trial for Toddlers With ASD

This research is being done to test the effectiveness of two treatments aimed at increasing language and social skills in children with autism spectrum disorder. If children show improveme...

Fingolimod in Schizophrenia Patients

This will be a single site safety and proof of concept study conducted at the Indiana University Psychotic Disorders Program. Forty subjects with schizophrenia or schizoaffective disorders...

Development of Ivermectin for Alcohol Use Disorders

Current pharmacotherapies for alcohol use disorders (AUDs) have limited efficacy. Thus, the development of effective treatments for AUDs represents an important public health objective. R...

Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders

The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of,...

Pharmacokinetics, Efficacy, and Safety Study of RI-002 (IGIV) in Subjects With Primary Immunodeficiency Diseases (PIDD)

This is a Phase III, multicenter, open-label study of RI-002 administered as an intravenous infusion of RI-002 (IGIV) every 21 or 28 days in approximately 60 subjects with Primary Immunode...

Effectiveness of Mexiletine for Treating People With Non-Dystrophic Myotonia

Nondystrophic myotonias (NDM) are neuromuscular disorders caused by genetic abnormalities in certain muscle cell membrane proteins. The proteins affect muscle contraction. Individuals with...

Dose-Escalation Safety Study of HPN-100 to Treat Urea Cycle Disorders

The purpose of this study is to determine whether HPN-100 is safe and tolerable in subjects with Urea Cycle Disorders.

An Interventional Study to Assess the Efficacy and Safety of Buprenorphine in Korean Patients With Spinal Disorders

The purpose of this study is to assess the pain reduction rate after 8 weeks treatment of NORSPAN® from baseline. And secondary purpose are: pain reduction rate after 4 weeks treatment f...

Videos

Spasmodic Dysphonia: A Peculiar Voice Disorder

Watch the follow-up to this video, "When Botox Disappoints": http://vimeo.com/79520222 Visit http://www.bastianmedicalmedia.com for more multimedia resources...

Medical and Biotech [MESH] Definitions

Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; LARYNGEAL MUSCLES; and VOCAL CORDS.

Branches of the vagus (tenth cranial) nerve. The recurrent laryngeal nerves originate more caudally than the superior laryngeal nerves and follow different paths on the right and left sides. They carry efferents to all muscles of the larynx except the cricothyroid and carry sensory and autonomic fibers to the laryngeal, pharyngeal, tracheal, and cardiac regions.

Branches of the VAGUS NERVE. The superior laryngeal nerves originate near the nodose ganglion and separate into external branches, which supply motor fibers to the cricothyroid muscles, and internal branches, which carry sensory fibers. The RECURRENT LARYNGEAL NERVE originates more caudally and carries efferents to all muscles of the larynx except the cricothyroid. The laryngeal nerves and their various branches also carry sensory and autonomic fibers to the laryngeal, pharyngeal, tracheal, and cardiac regions.

Abnormal accumulation of fluid in tissues of any part of the LARYNX, commonly associated with laryngeal injuries and allergic reactions.

Pathological processes that affect voice production, usually involving VOCAL CORDS and the LARYNGEAL MUCOSA. Voice disorders can be caused by organic (anatomical), or functional (emotional or psychological) factors leading to DYSPHONIA; APHONIA; and defects in VOICE QUALITY, loudness, and pitch.

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