Lipitor - Biotech, Pharma and Life Science Channel
Lipitor was the best selling drug in 2009, with the 2009 annual sales coming in at over $5m for its company, Pfizer Inc. Lipitor is the brand name for an atorvastatin calcium medication that is prescribed to lower cholesterol and triglycerides in the the blood. Part of its success is due to the endemic nature of hyperlipidemia and high cholesterol in western populations, and the risks that these conditions pose; including serious diseases such as strokes, and cardiovascular disease. It can also be used for patients with Diabetes, protecting against vascular-related problems.
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News Articles
Benefit of statins for impotence uncertain
"Statins could be a cheap and effective treatment for erectile dysfunction," reports the Daily Mail. Sadly, for those affected by erectile dysfunction (impotence), the Mail’s claim is no...
Consumer Reports: So Many Drugstores, So Many Prices; New Report Finds Price Mayhem At The Pharmacy
Tips for getting the best prices when you shop at the pharmacy; plus, why it pays to shop like a country mouse YONKERS, N.Y., March 28, 2013 /PRNewswire-USNewswire/ -- Con...
Generic Statins to Slash Global Market Value by 2018.
The introduction of generic statins has kick-started a decline that will see the global statins market lose over US$7 billion in revenue by 2018, states the latest report by business intelligence...
Technical Review: New Releases from Drug Maker Majors Cushion Against Patent Cliff Effects
LONDON, January 16, 2013 /PRNewswire/ -- All companies mentioned in the release below have received technical review as of the close of yesterday's session. These reports are available for free at ht...
ROCHELLE PARK, N.J., Nov. 29, 2012 (GLOBE NEWSWIRE) -- Gainey & McKenna announces that a class action lawsuit has been filed in the United States District Court, District of New Jersey on behalf...
NEW YORK, Nov. 21, 2012 /PRNewswire/ -- As in the previous quarter, proton-pump inhibitors, antipsychotics and statins remain in the top-selling therapeutic categories. Merck's asthma and allergy...
Pfizer loses Viagra patent - comment from the Economist Intelligence Unit
This ruling is clearly a big blow for Pfizer, which has already been forced to accelerate cost-cutting after the patent on its biggest drug Lipitor expired in the US in November 2011 and elsewhere t...
QMedRx Considers Patent's Role in Branded and Generic Drugs
MAITLAND, FL -- (Marketwire) -- 10/25/12 -- In the pharmaceutical industry, leading brands are able to build a sturdy consumer base as they maintain the exclusive rights to sell under the protection...
Pfizer is in a deal to acquire NextWave - comment from the Economist Intelligence Unit
Pfizer has long been keen to expand its product range in order to offset the effect of patent expiries on key drugs such as Lipitor. One interesting aspect of this acquisition, though, is that it sh...
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Clinical Trials
Effect of Statins on Oxidative Stress and Endothelial Progenitor Cells
Individuals with a high cholesterol level, diabetes or metabolic syndrome (collection of abnormalities such as high blood pressure, high triglyceride levels [fat], obesity, high blood gluc...
Lipitor Trial To Study The Effect Of Torcetrpib/Atorvastatin To Atorvastatin Alone.
The Torcetrapib project was terminated on December 2, 2006 due to safety findings. To look at various lipids in the blood of people with Fredrickson Type IIa and Type IIb mixed dyslipidem...
Rho Kinase in Patients With Atherosclerosis
The purpose of the study is to investigate the effects of atorvastatin (Lipitor) and rosuvastatin (Crestor), United States Food and Drug Administration (FDA) approved drugs commonly prescr...
Pediatric Kidney Transplant Without Calcineurin Inhibitors
The purpose of this study is to see the effect of using drugs other than calcineurin inhibitors to improve the rate of kidney transplant failure. Kidney transplantation can help children...
Anti Ischemic Effects of Abciximab in Angioplasty and Stenting Patients
AIR STUDY TITLE: Anti-Ischemic effects of Abciximab(Reopro) PATIENT POPULATION: Patients undergoing PCI(an interventional procedure placing a small stent/metallic tube to keep a na...
Effect of Atorvastatin (Lipitor) on Gene Expression in People With Vascular Disease
This study will determine if the drug Atorvastatin (Lipitor) changes the genetic material found in blood cells of people with vascular (blood vessel) disease. Vascular diseases affect the...
Slo-Niacin and atorvastatin (Lipitor) are both drugs that lower cholesterol. In this research, we will compare the effectiveness of Slo-Niacin and atorvastatin taken alone and together....
Lipitor In The Prevention Of Stroke, For Patients Who Have Had A Previous Stroke
To determine whether Lipitor reduces stroke, compared to placebo in patients who have had a previous stroke or transient ischemic attack.
Use of Atorvastatin (Lipitor) to Decrease Panel Reactive Antibody Titers
The purpose of this study is to identify subjects who are highly sensitized with antibodies. It is difficult for these patients to find suitable kidneys. We propose to treat such patients...
Atorvastatin (Lipitor) to Prevent Bone Pain
In the proposed randomized double blind cross-over placebo controlled study, the researchers intend to investigate if Atorvastatin (FDA approved statin for children) can be used to allevia...
PubMed Articles
Lipitor goes generic: business as usual or more big business?
We determined the effect of atorvastatin on myocardial apoptosis and caspase-8 activation following coronary microembolization (CME) in a rat model. For this, 50 rats were randomly and equally divided...
The influence of the phenolic hydroxyl group of ortho-hydroxy atorvastatin metabolite (Ato-OH) on the photochemistry of atorvastatin (Ato) has been evaluated by steady and time-resolved experiments. D...
Videos
Lipitor (Atorvastatin Calcium)
A pharmacist explains how Lipitor works, why doctors prescribe this cholesterol medication, and common side effects of the drug.Watch More Health Videos at H...