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Lower Esophageal Ring - Biotech, Pharma and Life Science Channel

23:59 EDT 23rd May 2013 | BioPortfolio

PubMed Articles [ 6815 Associated PubMed Articles listed on BioPortfolio]

Changes in peripheral blood immune cells: their prognostic significance in metastatic renal cell carcinoma patients treated with molecular targeted therapy.

Recently, novel molecular targeted agents markedly changed the treatment of renal cell carcinoma (RCC), with promising results. However, there is little understanding of how these agents affect immune...

Treatment for hepatitis C virus-induced portal hypertension in leukemic children.

Children with acute leukemia are at high risk of hepatitis C infection, either by immunosuppression secondary to chemotherapy or by multiple transfusions of blood products during the course of the dis...

IL28B minor allele is associated with a younger age of onset of hepatocellular carcinoma in patients with chronic hepatitis C virus infection.

BACKGROUND: IL28B polymorphisms were shown to be associated with a response to peg-interferon-based treatment in chronic hepatitis C (CHC) and spontaneous clearance. However, little is known about how...

Cytoplasmic non-epithelial mucin accumulation associated with CD44 in an astrocytic tumor with signet ring features.

We report a case of an atypical astrocytic tumor rich in signet ring cells with cytoplasmic mucin and glycogen in the left lower temporal lobe of the brain found in a Japanese female tricenarian. The...

Experimental and theoretical study of the intramolecular C-H···N and C-H···S hydrogen bonding effects in the (1) H and (13) C NMR spectra of the 2-(alkylsulfanyl)-5-amino-1-vinylpyrroles: a particular state of amine nitrogen.

In the (1) H NMR spectra of the 1-vinylpyrroles with amino- and alkylsulfanyl groups in 5 and 2 positions, an extraordinarily large difference between resonance positions of the HA and HB terminal met...

Thermal induced intramolecular 2 + 2 cycloaddition of allene-ACPs.

A facile synthetic method for preparation of bicyclo[4.2.0] nitrogen heterocycles has been developed via a thermal induced intramolecular [2 + 2] cycloaddition reaction of allene-ACPs. The DFT calcula...

Investigating Relative Respiratory Effort Signals During Mixed Sleep Apnea Using Photoplethysmogram.

Sleep disordered breathing does show different types of events. These are obstructive apnea events, central apnea events and mixed sleep apnea (MSA) which have a central component with a pause in airf...

Large deletions encompassing the TCOF1 and CAMK2A genes are responsible for Treacher Collins syndrome with intellectual disability.

Mandibulofacial dysostosis is part of a clinically and genetically heterogeneous group of disorders of craniofacial development, which lead to malar and mandibular hypoplasia. Treacher Collins syndrom...

Reductive Carbonylation of Aryl Halides Employing a Two-Chamber Reactor: A Protocol for the Synthesis of Aryl Aldehydes Including 13C- and D-Isotope Labeling.

A protocol has been developed for conducting the palladium-catalyzed reductive carbonylation of aryl iodides and bromides using 9-methylfluorene-9-carbonyl chloride (COgen) as a source of externally d...

A flexible C-terminal linker is required for proper FtsZ assembly in vitro and cytokinetic ring formation in vivo.

Assembly of the cytoskeletal protein FtsZ into a ring-like structure is required for bacterial cell division. Structurally, FtsZ consists of four domains: the globular N-terminal core, a flexible link...

News Articles [ 4932 Associated News Articles listed on BioPortfolio]

Study links iodine deficiency in pregnancy with poor cognitive outcomes in children

A study of nearly 1000 pregnant women from the United Kingdom has found that two thirds were deficient in iodine and that this deficiency was associated with a lower IQ and poorer reading ability in.....

New DRE, Inc. LED Conversion Kit Allows Doctors to Upgrade Older Halogen Technology Without Replacing Entire Lighting Systems

The DRE Xavier-C3 LED Conversion Kit upgrades older halogen surgical headlights to LED technology for improved patient outcomes, better vision in the surgical field and lower cost and maintenance. Lou...

CFDA Approves Clinical Trials for Novel China AIDS Treatment

A novel treatment for AIDS, developed in the Zhengzhou University labs of Junbiao Chang, PhD, has been approved by the CFDA for human trials. The molecule, which has been in development for ten years,...

Malaysia IHH's Q1 net profit up 3.67 pct

KUALA LUMPUR, May 23 (Reuters) - Malaysia's IHH Healthcare Bhd, the world's second-largest listed private healthcare provider by market value, posted a 3.67 percent rise in first-quarter profit, drive...

Fish oil 'may lower diabetes risk'

Fish oil capsules might help in the fight against diabetes, according to new research.

FDA panel recommends Merck’s insomnia drug for approval

An FDA advisory panel has voted in favour of Merck & Co's experimental insomnia drug, saying that it is safe and effective for elderly patients at the lower of two doses studied. While the FDA doe...

US FDA advisory panel backs approval of Merck & Co's suvorexant, but only at lower doses

The US Food and Drug Administration's Peripheral and Central Nervous System Drugs Advisory Committee yesterday voted 13 to three to approve drug giant Merck & Co's (NYSE: MRK) investigational insomnia...

Merck's insomnia drug moves a step closer to U.S. approval

WASHINGTON (Reuters) - Merck & Co's experimental insomnia drug moved a step closer to U.S. approval on Wednesday after a panel of medical experts said it is effective and safe at lower doses.

UPDATE 2-Merck's insomnia drug moves a step closer to U.S. approval

* FDA panel says suvorexant safe, effective at lower doses

Global Cell Culture Market Forecast to Hit $16.85B in 2018

Asia-Pacific is expected to be the fastest growing region, growing at a high CAGR of 15.6%, due to the emergence of many small regional players, lower operating costs and growing economies.

Events [ 1 Associated Events listed on BioPortfolio]

Molecular Medicine Congress

Welcome to Molecular Medicine Congress and exhibition.

Companies [ 128 Associated Companies listed on BioPortfolio]

RxEOB

Working closely with payers nationwide, including Blues plans, regional payers, and national carriers, RxEOB allows health plans to maximize the value of their pharmacy programs--reducing costs while...

TherapeuticsMD, Inc.

TherapeuticsMD™ is the parent company of vitaMedMD™, a specialty pharmaceutical company. vitaMedMD™ specializes in delivering the highest quality of products for wo...

Catasys, Inc.

Catasys, Inc. provides specialized behavioral health management services to health plans, employers and unions through a network of licensed and company managed health care provid...

DR Systems, Inc.

DR Systems, Inc. is the leading independent provider of enterprise imaging and information management systems for hospitals, integrated healthcare networks and diagnostic imaging...

Matrix-Bio, Inc.

Founded in 2006, Matrix-Bio, Inc., is an Indiana-based life science company focused on the development and commercialization of advanced metabolite profiling-based blood tests for...

Cascade Technologies Corp.

Cascade Technologies Corp., through its wholly-owned subsidiary Spectral Molecular Imaging, Inc. (SMI), is a development-stage medical imaging device company, applying its proprie...

Alaska Communications Systems Group, Inc.

Headquartered in Anchorage, Alaska Communications Systems Group, Inc. (“ACS”) (NASDAQ:ALSK), through its subsidiaries, provides Alaska Communications services and is Ala...

Cascade Technologies Corporation

Cascade Technologies Corp., through its wholly owned subsidiary Spectral Molecular Imaging, Inc., is a development-stage, medical imaging device company, applying its proprietary...

Capson

Capson is a new medical malpractice insurance provider challenging the status quo by offering innovative products and services to help healthcare providers run their practices mor...

Wellsource, Inc.

Wellsource, Inc. (www.wellsource.com), based in Portland, Oregon, is a leader in the development of evidence-based health risk assessments, online wellness libraries, activ...

Clinical Trials [ 1278 Associated Clinical Trials listed on BioPortfolio]

Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression

Background: - Atherosclerosis (thickening of the artery walls caused by cholesterol and other deposits) commonly occurs in the heart vessels and carotid (neck) arteries of adults. This i...

Connect 'n Unite: Couples-Based HIV/STI Prevention for Drug-Involved, Black MSM

This study rigorously tests the efficacy of a couples-based HIV and sexually transmitted infection (HIV/STI) preventive intervention for African American/Black men who have sex with men (M...

A Study to Determine the Relative Bioavailability of the MEK Inhibitor, Trametinib, in Subjects With Solid Tumor Malignancies

This is an open-label, randomized, single-dose, 2-treatment, 2-period, 2-way crossover study with incomplete wash-out in subjects with solid tumors to determine the relative bioavailabilit...

Genitourinary Symptoms With Levonorgestrel Releasing Intrauterine Systems

The main purpose of the study was to evaluate the efficacy of Levonorgestrel Releasing Intrauterine devices (LNR-IUD) on genitourinary symptoms in patients with abnormal uterine bleeding....

cSBI-M for Young Military Personnel

The goal of this project is to test the efficacy of a computer-facilitated Screening and Brief Intervention system adapted for Military use (cSBI-M) in reducing substance use among 18- to...

Host Immune Response to Clostridium Difficile Infection in Inflammatory Bowel Disease Patients

The inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn's disease (CD) are chronic conditions affecting approximately 1.4 million Americans. The burden of Clostridium dif...

Risk Factors for Gastric Disease in Pediatric Helicobacter Pylori (H. Pylori)

Helicobacter pylori (Hp) is a major cause of chronic-active gastritis and primary duodenal ulcers, and is strongly linked to gastric cancer. Most Hp infections worldwide are acquired in c...

Paraplegic Cycling: Improving Health After Spinal Cord Injury

Surface electrical stimulation has for many years been widely used to retrain paralysed muscle and achieve the functions of standing and stepping. Recently a number of centres have used el...

Comparison of Humidification Devices During Non Invasive Ventilation, in Acute Respiratory Failure

Comparison of humidification devices during non invasive ventilation, in acute respiratory failure. The hypothesis was, due to dead space, lower humidification, a reduced efficiency of th...

Pre-hospital Administration of Thrombolytic Therapy With Urgent Culprit Artery Revascularization

The PATCAR study has been designed to test the hypothesis that the strategy of pre-hospital use of a "clot busting" (thrombolytic) drug followed with emergent heart catheterization includi...

Medical and Biotech [MESH] Definitions

Cyclooctanes

A group of compounds with an 8-carbon ring. They may be saturated or unsaturated.

Aristolochic Acids

Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINES) by oxidative ring cleavage. The nitro group is a reactive alkylator (ALKYLATING AGENTS) that binds to biological macromolecules. Ingestion by humans is associated with nephropathy (NEPHRITIS). There is no relationship to the similar named aristolochene (SESQUITERPENES).

Lower Extremity

The region of the lower limb in animals, extending from the gluteal region to the FOOT, and including the BUTTOCKS; HIP; and LEG.

Oxocins

Compounds based on an 8-membered heterocyclic ring including an oxygen. They can be considered medium ring ethers.

Pterocarpans

A group of compounds which can be described as benzo-pyrano-furano-benzenes which can be formed from ISOFLAVONES by internal coupling of the B ring to the 4-ketone position. Members include medicarpin, phaseolin, and pisatin which are found in FABACEAE.

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