Lung Cancer - Biotech, Pharma and Life Science Channel
Lung cancer is the uncontrolled cell growth in tissues of the lung. Originating in the lungs, this growth may invade adjacent tissues and infiltrate beyond the lungs. Lung cancer, the most common cause of cancer-related death in men and women, is responsible for 1.3 million deaths worldwide annually, as of 2004. The most common symptoms are shortness of breath, coughing (including coughing up blood), and weight loss.
The main types of lung cancer both originate from epithelial cells but can be small cell (respond well to chemotherapy or radiotherapy) or non-small cell (which respond better to surgery) carcinomas. Long-term exposure to tobacco smoke is the most common cause of lung cancers, but other causes include genetics and environmental factors. The overall five-year survival rate for lung cancer is 14%.
Source; adapted from Wikipedia
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News Articles
LOS ANGELES, May 24, 2013 /PRNewswire/ -- An international roster of experts on malignant pleural mesothelioma (MPM) gathered on Saturday, May 18, in Santa Monica, Calif., to discuss their latest...
Med BioGene Announces Warrant Exercises
VANCOUVER, BRITISH COLUMBIA -- (Marketwired) -- 05/24/13 -- Med BioGene Inc. (TSX VENTURE: MBI) today announced that 2,318,000 warrants and agents' warrants to purchase an equal number of common sha...
Clinical trial tests targeting prostate cancer treatment
ANN ARBOR, Mich., May 23, 2013 /PRNewswire-USNewswire/ -- Are certain drugs more effective against some types of prostate cancers than others? Researchers know that not all therapies work for all...
ARIAD to Present at the Deutsche Bank 38th Annual Healthcare Conference
ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that it will present at the Deutsche Bank 38th Annual Healthcare Conference being held in Boston. Harvey J. Berge...
Celgene Announces U.S. FDA Grants Priority Review for ABRAXANE® sNDA in Advanced Pancreatic Cancer
European Medicines Agency Accepts Regulatory Submission of Type II Variation for ABRAXANE for the Treatment of Advanced Pancreatic Cancer Celgene International Sàrl, a subsid...
Cancer Genetics to Present at Marcum MicroCap Conference
Cancer Genetics, Inc. (OTCQB: CGIX) ("CGI" or the "Company"), an emerging leader in DNA-based cancer diagnostics, will present at the second annual Marcum MicroCap Conference on T...
Lung Cancer Alliance Wins Big During Awards Week
WASHINGTON, May 23, 2013 /PRNewswire-USNewswire/ -- Lung Cancer Alliance announced today that it was awarded a Bronze Effie Award in the Disease Awareness and Education category, and a Silver OBI...
BOTHELL, Wash. and VANCOUVER, British Columbia, May 23, 2013 /PRNewswire/ -- OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI) today announced plans for the initiation of the Cedar™ clini...
TORONTO, ONTARIO -- (Marketwired) -- 05/23/13 -- Editors Note: There is a photo associated with this press release. Soricimed Biopharma Inc., a private clinical stage company developing novel cancer...
Jennerex Completes $21.6 Million Private Placement
SAN FRANCISCO, CA -- (Marketwired) -- 05/23/13 -- Jennerex Biotherapeutics, Inc., a private, clinical-stage biotechnology company focused on the development and commercialization of best-in-class tar...
Events
Cancer Vaccines will provide attendees with a complete view of the cancer immunotherapy field. Focusing on the discovery of new vaccines, developments in target identification
Select Bio is pleased to present the 3rd Screening Asia conference, which will take place at the Biopolis, Singapore, on November 12th & 13th
3rd Annual Oncology Biomarkers Congress 2013
Over 150 oncology focused industry delegates Over 50 presentations/roundtables/panel discussions
3rd World Congress on Cancer Science & Therapy
3rd world congress on Cancer Science & Therapy serves as a reunion land for scientists in the area of cancer research.
Companies
The Multiple Myeloma Research Foundation
Multiple myeloma is an incurable blood cancer. The five-year relative survival rate for multiple myeloma is approximately 34 percent, one of the lowest of all cancers. In 2009, ap...
Transgene (NYSE-Euronext: TNG), a member of the Institut Mérieux Group, is a biopharmaceutical company. It creates, develops and manufactures targeted immunotherapeutics for th...
American Cancer Society Cancer Action Network
The American Cancer Society combines an unyielding passion with nearly a century of experience to save lives and end suffering from cancer. As a global grassroots force of more th...
ALung Technologies, Inc. is commercializing artificial lung devices for the treatment of acute and chronic respiratory disorders. The company's Hemolung System, designed to replace or supplement the u...
Loma Linda University Medical Center
Loma Linda University Medical Center (LLUMC), a Seventh-Day Adventist institution, is among the largest private medical educational centers in the United States and the only one in inland Southern...
Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...
Bio-Path is developing a patented, liposomal drug delivery system and products developed at The University of Texas M. D. Anderson Cancer Center, with two clinical cancer drug can...
Cancer Genetics, Inc. (CGI) is an emerging leader in the field of personalized medicine, offering products and services that enable cancer diagnostics as well as treatments that are tailored to the...
Foundation Medicine is dedicated to the development of comprehensive tests that will help physicians personalize cancer treatment for their patients. Foundation Medicineâs la...
Eutropics Pharmaceuticals Inc.
Eutropics is addressing the need for improving the treatment of aggressive forms of leukemia, myeloma, lymphoma, and other cancers. The company is developing a novel diagnostic te...
Clinical Trials
The purpose of this study is to see if different types of surgery for lung cancer have different effects on quality of life and pain. What we learn from this study may help us find new way...
Exercise and Metformin in Colorectal and Breast Cancer Survivors
Metformin is a medication that is commonly used in the treatment of diabetes. Recently small studies in cancer patients without diabetes suggest that metformin may benefit in lowering ins...
This prospective, multi-center, non-interventional study will evaluate the efficacy and safety of Herceptin (trastuzumab) in routine clinical practice in Chinese patients with gastric or g...
Cell Lines From High-Risk Breast Tissue
Background: - Many risk factors for breast cancer have been identified, including family history, endocrine background, changes in breast tissue, cancer in one breast, radiation...
Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants
To determine whether or not inhaled nitric oxide (iNO) safely decreases the incidence of chronic lung disease (CLD) in premature infants.
RATIONALE: Dasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase II trial is studying how well dasatinib works in treati...
Phase 2A Study of NPC-1C Chimeric Monoclonal Antibody to Treat Pancreatic and Colorectal Cancer
The purpose of the phase 2A component of this study is to determine if giving the immune molecule NPC-1C to individuals who have cancer of the pancreas or gastrointestinal tract (colon or...
Neoadjuvant Axitinib in Prostate Cancer
The goal of this clinical research study is learn if adding axitinib to hormonal therapy can help to control prostate cancer when given before surgery. The safety of this drug will also be...
Testing the Helpfulness of 2 Decision Aids for Prostate Cancer
The purpose of this study is to test different methods for communicating information about prostate cancer treatment to men. The investigators are studying how best to present information...
Study of Everolimus, Pemetrexed, Carboplatin, and Bevacizumab to Treat Stage IV Lung Cancer
The purpose of this study is to identify a well-tolerated dose of everolimus in combination with chemotherapy treatment for patients with advanced lung cancer.
PubMed Articles
Clinical significance of tumor cavitation (TC) prior to and following first-line chemotherapy of lung cancer is unclear. An evaluation of the incidence and prognostic role of TC among treatment naive...
Estrogens and IL-12 play a pivotal role in the development and progression of non-small-cell lung cancer (NSCLC); at the same time, estrogen receptor β2 and (interleukin-12 receptor β2)IL-12Rβ2 are...
Arrhythmias during and after zoledronic acid infusion patients with bone metastasis.
Zoledronic acid (ZA) is one of the important bisphosphonates which is widely used in bone metastatic cancer and osteoporotic patients. In a few studies, it has been reported that treatment with bispho...
PR (PRDI-BF1 and RIZ) domain containing proteins (PRDM) have been indicated to play important roles in several human cancers. The objectives of this study were to determine the frequency and prognosti...
The influence of genetic polymorphisms in MDR1 gene on breast cancer risk factors in Chinese.
Breast cancer (BC) is the most common cancer among women in the world. The human multidrug resistance 1 gene (MDR1) is potentially an important gene influencing the susceptibility to breast cancer. Th...
Prognostic value of TMPRSS4 expression in patients with breast cancer.
Transmembrane protease, serine 4 (TMPRSS4), is a novel type II transmembrane serine protease that is highly expressed on the cell surface in pancreatic, thyroid, lung, and other cancer tissues, althou...
Breast cancer is the most common cancer in women worldwide. The disease remains a public health concern as recent evidence indicates that the breast cancer burden has increased mainly in developing an...
Expression and prognostic significance of GATA-binding protein 2 in colorectal cancer.
GATA-binding protein 2 (GATA2) is a nuclear transcription factor that plays a critical role in tumorigenesis. High levels of GATA2 expression are correlated with poor survival outcomes in many types o...
Clinical significance of serum adipokines levels in lung cancer.
Adipokines have a significant effect on metabolism, immunoinflammatory responses as well as on carcinogenesis; therefore, we aimed at evaluating their potential predictive and prognostic significance...
p73 gene shares structural and functional similarities to p53 and plays an important role in modulating cell cycle arrest and apoptosis. A common non-coding polymorphism of p73 G4C14-to-A4T14 (rs22739...
Videos
[English] MAKNA Getting to know Lung Cancer
Lung cancer is an uncontrolled growth of abnormal cells in the lungs, producing a growth called a tumour. Cancerous tumours, called malignant tumours, can sp...
Medical and Biotech [MESH] Definitions
Dynamin Iii
A subtype of dynamin found expressed exclusively in the testis, lung and brain.
Receptor, Epha1
The founding member of the EPH FAMILY RECEPTORS. It was first cloned from an erythropoietin-producing human hepatocellular carcinoma cell line and is highly conserved among many mammalian species. Overproduction of the EphA1 receptor is associated with tumors and tumor cells of epithelial origin. It is also expressed at high levels in LIVER; LUNG; and KIDNEY; which is in contrast to many other members of the Eph receptor that are found primarily in tissues of the nervous system.
Receptor, Epha2
An Eph family receptor found abundantly in tissues of epithelial origin. It is expressed in a diverse array of tissues during embryonic development, suggesting that it may play a role in embryogenesis. In adult tissues high levels of the receptor are expressed in the LUNG; SKIN; SMALL INTESTINE and OVARY.
Receptor, Ephb3
An eph family receptor found in a number of tissues including BRAIN; LUNG; KIDNEY; PANCREAS; INTESTINE; and HEART. During embryogenesis EphB3 receptor is expressed at high levels in the brain.
Ephrin-a1
An ephrin that was originally identified as the product of an early response gene induced by TUMOR NECROSIS FACTORS. It is linked to the CELL MEMBRANE via a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR and binds EPHA2 RECEPTOR with high affinity. During embryogenesis high levels of ephrin-A1 are expressed in LUNG; KIDNEY; SALIVARY GLANDS; and INTESTINE.
