Lymphoma relapse - Biotech, Pharma and Life Science Channel
PubMed Articles
Despite the well-defined role of autologous haematopoietic stem cell transplantation (autoHCT) in the treatment of patients with relapsed or refractory Hodgkin lymphoma (HL), relapse remains the main...
Secondary mucosa-associated lymphoid tissue (MALT) lymphoma of the colon.
Mucosa-associated lymphoid tissue (MALT)-type lymphomas most commonly occur in the stomach and have been associated with Helicobacter pylori infection. However, MALT-type lymphoma of the colon is a ra...
8p21.3 deletion was recently characterized in B cell lymphoma suggesting that TRAIL-R1 and TRAIL-R2 may be the target of the deletion and act as dosage-dependent tumor suppressor genes. As multiple my...
MicroRNA-215 inhibits relapse of colorectal cancer patients following radical surgery.
To investigate the role of miR-215 in the relapse following radical surgery of colorectal cancer patients. The clinical data and surgical frozen tumor tissues were retrospectively collected from 125 s...
Expression of CD133 in acute leukemia.
There have been conflicting results regarding a correlation between CD133 expression and disease outcome. To assess CD133 expression in patients with acute myeloid leukemia (AML) and acute lymphoblast...
Topical calcineurin inhibitors (TCIs), commercially available since 2000-2001, are the first and only topical medications approved for chronic treatment of atopic dermatitis (AD) in pediatric patients...
Neither accurate incidence nor survival data for pediatric patients with hematological malignancies (HM) have been available in Japan to date. Incidence of patients under 20 years of age, who were di...
Terminal deoxynucleotidyl transferase (TdT) can be downregulated in minimal residual disease of T-acute lymphoblastic leukemia/lymphoma (T-ALL/LBL) after chemotherapy. TdT-negative T-ALL/LBL cases are...
Co-existence of PML-RARα and BCR-ABL in Acute Promyelocytic Leukemia (APL).
The relationship between FDG uptake and clinicopathological factors in DLBCL patients.
ABSTRACT The aim of this study was to investigate the correlations between the standardized uptake value of the biopsy site (BSUV max) and the levels of glucose transporter (GLUT)-1, GLUT-3, and hexok...
News Articles
Anti-Cancer Drug Reverses Alzheimer's Disease In Mice
An anti-cancer drug may reverse memory problems in an Alzheimer's Disease mouse model, according to new research carried out at the University of Pittsburgh Graduate School of Public Health. The study...
Florida Drug Rehab Destination Hope Kicks Off Summer Relapse Prevention Program
Destination Hope’s summer relapse prevention program aims to target individuals in recovery during one of the most high risk times of the year. Fort Lauderdale, FL (PRWEB) May 24, 2013 Destination...
News digest – inherited cancer genes, beta-blockers, non-Hodgkin lymphoma and more
Here’s a round-up of this week’s cancer news: A new research programme announced this week will lay the foundations for routine testing for inherited cancer genes in patients with the dise...
Radioactive Nanoparticles Developed That Target Cancer Cells
Cancers of all types become most deadly when they metastasize and spread tumors throughout the body. Once cancer has reached this stage, it becomes very difficult for doctors to locate and treat the n...
Drug reverses Alzheimer's disease deficits in mice
An anti-cancer drug reverses memory deficits in an Alzheimer's disease mouse model, new research shows. The article reviewed previously published findings on the drug bexarotene, approved by the US Fo...
Non-Hodgkin lymphoma survival doubles since early 1970s
More than half of patients diagnosed with Non-Hodgkin Lymphoma (NHL) are now surviving the disease thanks to improved diagnosis and treatment, according to a new report1 from Cancer Research UK.
Drug reverses Alzheimer's disease deficits in mice, Pitt research confirms
(University of Pittsburgh Schools of the Health Sciences) An anti-cancer drug reverses memory deficits in an Alzheimer's disease mouse model, University of Pittsburgh Graduate School of Public Health...
WHITE PLAINS, N.Y., May 22, 2013 /PRNewswire/ -- The Leukemia & Lymphoma Society (LLS) is committing approximately $6 million to Valor Biotherapeutics, LLC, a joint venture between ImmunGene...
Researchers develop radioactive nanoparticles that target cancer cells
Cancers of all types become most deadly when they metastasize and spread tumors throughout the body. Once cancer has reached this stage, it becomes very difficult for doctors to locate and treat the n...
Events
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Companies
Eutropics Pharmaceuticals Inc.
Eutropics is addressing the need for improving the treatment of aggressive forms of leukemia, myeloma, lymphoma, and other cancers. The company is developing a novel diagnostic te...
Nimbus Discovery is applying advances in computer-based drug discovery to develop new medicines against important drug targets and thereby unlock fundamental biological pathways....
The Leukemia & Lymphoma Society and Reliant Energy
The Leukemia & Lymphoma Society ® (LLS) is the worldâs largest voluntary health agency dedicated to blood cancer. The LLS mission: Cure leukemia, lymphoma, Hodgkinâ...
Yaupon Therapeutics, a privately held, specialty pharmaceutical company, is developing a proprietary gel formulation of mechlorethamine hydrochloride for the treatment of early st...
Ceptaris Therapeutics, Inc. is a privately held, specialty pharmaceutical company that is developing a proprietary gel formulation of mechlorethamine hydrochloride for the treatme...
Shape Pharmaceuticals, Inc. is developing SHP-141, a novel, topical, âsoft-drugâ HDAC inhibitor for the treatment of patients with cutaneous T cell lymphoma (CTCL) and p...
Biovest International, Inc. is an emerging leader in the field of active personalized immunotherapies targeting life-threatening cancers of the blood system. Developed in collabor...
Allos Therapeutics, Inc. (Nasdaq: ALTH) is a biopharmaceutical company committed to the development and commercialization of innovative anti-cancer therapeutics. Allos is currentl...
Xencor, Inc. engineers superior biotherapeutics using its proprietary Protein Design Automation® technology platform, and is a leader in the field of antibody engineering to si...
Gamida Cell is a world leader in stem cell population expansion technologies and stem cell therapy products for transplantation and regenerative medicine. The companyâs pipel...
Clinical Trials
Background: - Studies conducted at the National Cancer Institute suggest that certain chemotherapy drugs may be more effective if given by continuous infusion into the vein rather...
Stem Cell Collection With Ofatumumab
The goal of this clinical research study is to learn if it is possible to collect stem cells after ofatumumab and chemotherapy treatment. This study will also evaluate side-effects, number...
RATIONALE: Herpesvirus is found in the cancer cells of patients with primary effusion lymphoma. Antiviral drugs, such as zidovudine and valganciclovir, may be able to act against the herpe...
RATIONALE: Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and he...
RATIONALE: Drugs used in chemotherapy, such as vorinostat, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Vorinos...
Rituximab and Gemcitabine for Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Rituximab has been demonstrated to sensitize drug-resistant NHL cells to the cytotoxic actions of several chemotherapy agents by enhancing sensitivity of tumor cells to chemotherapy-induce...
Aim of the study is to assess the therapeutic activity and safety of the combination of Chlorambucil and Rituximab in MALT lymphomas and to determine whether the addition of Rituximab to C...
Development of an Evaluation Method of Elderly Condition in Patient Receiving Chemotherapy Treatment
Number of elderly people over 70 is increasing in France. In 2002, in the south-west, 273,741 of them were over 75 years, i.e. 9.2% of Aquitaine population. Incidence of cancer in this old...
Naltrexone Implants vs. MMT Among Inmates in the Norwegian Correctional Services
The purpose of this clinical trial is to study the efficacy and safety of naltrexone implants as a relapse prevention for opiate addicted inmates about to be released from prison. The expe...
Positron Emission Tomography (PET) Interest in the Follow Up of Colorectal Cancer Stage II and III
The follow up of colorectal cancer after curative surgery has to find loco-regional relapses or synchronous metastases, and to detect adenomas and new cancer on the rest of the colon. The...
Videos
An Expert's Perspective on Novel Approaches for Relapse Refractory Hodgkin Lymphoma
Dr. Stephen Ansell, a hodgkin lymphoma expert, explains exciting new treatment options for relapse refractory Hodgkin lymphoma with advancements of agents su...
Medical and Biotech [MESH] Definitions
Candida Tropicalis
A species of MITOSPORIC FUNGI that is a major cause of SEPTICEMIA and disseminated CANDIDIASIS, especially in patients with LYMPHOMA; LEUKEMIA; and DIABETES MELLITUS. It is also found as part of the normal human mucocutaneous flora.
Oncogene Protein V-cbl
An oncoprotein from the Cas NS-1 murine retrovirus that induces pre- B-CELL LYMPHOMA and MYELOID LEUKEMIAS. v-cbl protein is a tyrosine-phosphorylated, truncated form of its cellular homologue, PROTO-ONCOGENE PROTEIN C-CBL.
Oncogene Protein V-akt
A viral oncoprotein originally isolated from a murine T CELL LYMPHOMA infected with the acutely transforming retrovirus AKT8. v-akt protein is the viral homologue of PROTO-ONCOGENE PROTEINS C-AKT.
Proto-oncogene Proteins C-bcl-6
A DNA-binding protein that represses GENETIC TRANSCRIPTION of target genes by recruiting HISTONE DEACETYLASES. Aberrant Blc-6 expression is associated with certain types of human B-CELL LYMPHOMA.
Precursor Cell Lymphoblastic Leukemia-lymphoma
A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
