MarchiafavaBignami Disease - Biotech, Pharma and Life Science Channel
PubMed Articles
The gluten-sensitive enteropathy celiac disease is tightly associated with the production of autoantibodies specific for the enzyme transglutaminase 2 (TG2). The mechanisms underlying the activation o...
Brain metal accumulation in Wilson's disease.
Brain metal accumulation is suggested in the pathogenesis of numerous neurodegenerative disorders. In Wilson's disease (WD), only copper has been examined. The aim of the present study was to evaluate...
Effect of camptocormia on lung volumes in Parkinson's disease.
Camptocormia is defined as an abnormal flexion of the thoracolumbar spine of 45°, or more, that typically increases during walking or standing and completely disappears in the supine position. Campto...
Immune activation and inflammation represent critical factors in the pathogenesis of Alzheimer's disease (AD) and are associated with increased blood concentrations of markers like neopterin and the k...
Cognitive slowing in Parkinson's disease is related to frontostriatal dopaminergic dysfunction.
Frontostriatal and cognitive dysfunctions in Parkinson's disease (PD) are hypothesized to be linked predominately to dopaminergic dysfunction within neural networks linking dorsal striatum to dorsolat...
Spondyloarthritis and inflammatory bowel disease : Comorbidity and treatment implications.
Spondyloarthritides (SpA) and inflammatory bowel disease (IBD) are chronic, idiopathic inflammatory disorders of the axial and peripheral joints and the intestinal tract, respectively, affecting up to...
Estrogen regulation of Dkk1 and Wnt/β-Catenin signaling in neurodegenerative disease.
17β-estradiol (E2 or estrogen) is an endogenous steroid hormone that is well known to exert neuroprotection. Along these lines, one mechanism through which E2 protects the hippocampus from cerebral i...
Inflammatory biomarkers and exacerbations in chronic obstructive pulmonary disease.
Exacerbations of respiratory symptoms in chronic obstructive pulmonary disease (COPD) have profound and long-lasting adverse effects on patients.
Chronic Kidney Disease in an Adult with Propionic Acidemia.
We report an adult male with classic propionic acidemia (PA) who developed chronic kidney disease in the third decade of his life. This diagnosis was recognized by an increasing serum creatinine and c...
News Articles
Plavix No Help in Kids' Cyanotic Heart Disease (CME/CE)
(MedPage Today) -- Children with cyanotic congenital heart disease derived no benefit from prophylactic clopidogrel for shunt thrombosis, a large, randomized trial showed.
By John Reisman: Things To Think About Some have already noted yesterday (June 18, 2013) that the American Medical Association is now classifying obesity as a disease. Today, the AMA adopted polic...
US doctors' group labels obesity a disease
(HealthDay)—In an effort to focus greater attention on the weight-gain epidemic plaguing the United States, the American Medical Association has now classified obesity as a disease.
AMA declares obesity a disease needing treatment
The American Medical Association declared obesity a disease, which means 90 million U.S. adults and children have a medical condition requiring treatment. (UPI)
AACE applauds the American Medical Association for recognizing obesity as disease state
The American Association of Clinical Endocrinologists (AACE) applauds the American Medical Association (AMA) House of Delegates for its action today to approve a resolution recognizing obesity as a di...
HHS Releases New Guideline to Reduce Disease Transmission Through Organ Transplantation
The U.S. Department of Health and Human Services (HHS) has released a new guideline to improve patient safety by reducing unexpected disease transmission through organ transplantation. This guideline...
Going against a recommendation by one of its committees to label it only a "major public health problem," the American Medical Association has recognized obesity as a disease. The New York Times: A.M....
MELBOURNE, AUSTRALIA -- (Marketwired) -- 06/19/13 -- Melbourne-based Prana Biotechnology (ASX: PBT) (NASDAQ: PRAN) has unveiled a world first, patient-reported outcomes study for Huntington's Disea...
Curing H. Pylori Cuts Parkinson's Symptoms (CME/CE)
SYDNEY (MedPage Today) -- Parkinson's disease patients showed improvement in multiple symptoms of the disease after being treated for Helicobacter pylori infection, researchers reported here.
Curing H. Pylori Cuts Parkinson’s Symptoms (CME/CE)
SYDNEY (MedPage Today) -- Parkinson's disease patients showed improvement in multiple symptoms of the disease after being treated for Helicobacter pylori infection, researchers reported here.
Events
5th annual COPD: Novel Therapeutics and Management Strategies conference
SMi Presents the 5th annual conference on COPD
Welcome to AgriGenomics World Congress 2013.
14th INTERNATIONAL CONFERENCE ON ALZHEIMER'S DRUG DISCOVERY
The annual Alzheimer's Drug Discovery Foundation (ADDF) conference brings together academic and industry scientists intent on accelerating the development of innovative treatments for Alzheimer’s di...
Companies
Resverlogix Corp. (TSX: RVX) is a clinical stage cardiovascular company with an epigenetic platform technology that modulates protein production. Resverlogix is developing RVX-208, a first-in-class...
Reverse Medical Corporation is a privately-held medical device company focused on expanding the endovascular management of acute stroke and neurovascular disease. The technology p...
Aegerion Pharmaceuticals, Inc.
Aegerion Pharmaceuticals is a biopharmaceutical company dedicated to the development and commercialization of innovative, life-altering therapies for patients with debilitating often fatal, rare dis...
Avaxia is a leader in the growing field of gut-targeted therapeutics — orally administered, minimally absorbed drugs that are designed to act locally in the gastrointestinal...
Sequenta, Inc. is a privately held company developing and commercializing molecular diagnostic assays based on a proprietary sequencing approach to the profiling of T and B cell r...
Symphogen A/S, the biotech company pioneering recombinant human polyclonal antibodies for the treatment and prevention of human disease, today announced the initial closing of a USD 25 million Series...
Civitas is a privately held pharmaceutical company focused on developing products with a clinically proven dry powder pulmonary delivery platform. The proprietary dry powder and d...
The Multiple Myeloma Research Foundation
Multiple myeloma is an incurable blood cancer. The five-year relative survival rate for multiple myeloma is approximately 34 percent, one of the lowest of all cancers. In 2009, ap...
KineMed, Inc. ("KineMed" or the "Company") is a drug discovery and development company employing its proprietary translational medicine technology (AquaTag™ and KineMarkerâÂ...
Diabetes Care Club, a Simplex brand, has grown to become the third largest mail-order supplier of diabetic testing supplies for seniors. The company provides home delivery...
Clinical Trials
A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)
The main purpose of the study is to evaluate the efficacy and safety of the study drug known as prasugrel for the reduction of Vaso-Occlusive Crisis events in pediatric participants with s...
Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders
The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of,...
An Efficacy and Safety Study of Galantamine for the Treatment of Patients With Alzheimer's Disease
The purpose of this study is to evaluate the efficacy and safety of two fixed doses (16mg/day and 24mg/day) of galantamine (a drug for treating dementia) versus placebo for the treatment o...
A Study in Patients With Diabetic Kidney Disease
The purpose of this study is to determine if LY2382770 is safe and effective at protecting kidney function in patients with kidney disease due to diabetes.
Parkinson's Disease Registry of the Muhammad Ali Parkinson Center
The purpose of the Parkinson’s disease Registry is to develop a national and international database of persons with Parkinson’s disease (PD). The Registry will be used to facilitate t...
D-Serine Adjuvant Treatment for Parkinson's Disease
The proposed experiment will evaluate the effects of the NMDA receptor full agonist D-serine (~2g/day) on persistent symptoms of Parkinson's Disease and on antiparkinsonian drugs-induced d...
The Fabry Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Fabry disease, irrespective of trea...
Study Of PHarmacogenetics in Ethnically Diverse Populations (SOPHIE Study)
Collect DNA from well-characterized healthy volunteers. DNA will be used to identify and determine allele frequencies of genetic variants in membrane transporters and other genes relevant...
Selenium Supplementation in Chronic Obstructive Pulmonary Disease (COPD) Patients
Does an oral selenium supplement increase blood levels of antioxidants in patients with established, smoking-related lung disease? Members of our study group recently discovered that elev...
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease
This study was designed to evaluate the symptomatic effects of Coenzyme Q10 nanodispersed solution in middle-stage Parkinson's disease (PD) patients (Hoehn&Yahr II to III). The treatment p...
Videos
Medical and Biotech [MESH] Definitions
Casuistry
A method of ETHICAL ANALYSIS that emphasizes practical problem solving through examining individual cases that are considered to be representative; sometimes used to denote specious argument or rationalization. Differentiate from casuistics, which is the recording and study of cases and disease.
Incidental Findings
Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.
Wasting Disease, Chronic
A transmissible spongiform encephalopathy (prion disease) of DEER and elk characterized by chronic weight loss leading to death. It is thought to spread by direct contact between animals or through environmental contamination with the prion protein (PRIONS).
Ulmus
A plant genus of the family ULMACEAE that is susceptible to Dutch elm disease which is caused by the ASCOMYCOTA fungus, Ophiostoma.
Virulence Factors
Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)
