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Mast cell stabilizers - Biotech, Pharma and Life Science Channel

14:53 EDT 20th May 2013 | BioPortfolio

PubMed Articles [ 4293 Associated PubMed Articles listed on BioPortfolio]

miR-22 is down-regulated in gastric cancer, and its overexpression inhibits cell migration and invasion via targeting transcription factor Sp1.

Accumulating evidence has shown that microRNAs are involved in multiple processes in cancer development and progression. Recently, miR-22 has been identified as a tumor-suppressing microRNA in many hu...

Hypermethylation and prognostic implication of Syk gene in human colorectal cancer.

The study was aimed to investigate the relationship between hypermethylation of Syk gene and clinicopathological characteristics and long-term outcomes in colorectal cancer. The effect of Syk on cell...

PTPN4 negatively regulates CrkI in human cell lines.

PTPN4 is a widely expressed non-receptor protein tyrosine phosphatase. Although its overexpression inhibits cell growth, the proteins with which it interacts to regulate cell growth are unknown. In th...

Characterization of antibody-polyol interactions by static light scattering: Implications for physical stability of protein formulations.

In this study, the nature of interactions between monoclonal antibodies and polyols was studied using static light scattering. Solutions of mAb-U and mAb-P (4-12mg/mL) were analyzed using static light...

Block copolymer stabilized nonaqueous biocompatible sub-micron emulsions for topical applications.

Polyethylene glycol (PEG) 400/Miglyol 812 non-aqueous sub-micron emulsions were developed due to the fact that they are of interest for the design of drug-loaded biocompatible topical formulations. Th...

Trichinella: What is going on during nurse cell formation?

Recent molecular studies have revealed that many genes are mobilized during nurse cell formation, including those involved in activation and proliferation of satellite cells, dedifferentiation, cell c...

Nonylphenol-induced apoptotic cell death in mouse TM4 Sertoli cells via the generation of reactive oxygen species and activation of the ERK signaling pathway.

Nonylphenol (NP), a representative endocrine disruptor, interferes with reproductive function in aquatic organisms and animals. Although many previous studies have focused on apoptotic cell death by N...

Pharmacological inhibition of macrophage migration inhibitory factor interferes with the proliferation and invasiveness of squamous carcinoma cells.

Recent clinical observations and experimental studies of our group indicate that macrophage migration inhibitory factor (MIF) may contribute to tumor progression in head and neck squamous cell carcino...

Controlled Cell Adhesion Using a Biocompatible Anchor for Membrane-Conjugated Bovine Serum Albumin/Bovine Serum Albumin Mixed Layer.

We report here a method for controlling cell adhesion, allowing simple yet accurate cell detachment from the substrate, which is required for the establishment of new cytometry-based cell processing a...

Apoptosis-inducing factor (AIF) and leukocyte elastase inhibitor/L-DNase II (LEI/LDNaseII), can interact to conduct caspase-independent cell death.

Programmed cell death is an important factor in tissue homeostasis. Lot of work has been performed to characterize the caspase-dependent cell death. Caspase-independent cell death, although important...

News Articles [ 7995 Associated News Articles listed on BioPortfolio]

New Kaiser Permanente study shows effectiveness of whole-cell pertussis vaccines

Whole-cell pertussis vaccines were more effective at protecting against pertussis than acellular pertussis vaccines during a large recent outbreak, according to a new Kaiser Permanente study published...

Cellular Biomedicine Group Achieves 50% Enrollment Milestone in Phase I Clinical Trial for Knee Osteoarthritis

PALO ALTO, Calif., May 17, 2013 /PRNewswire/ -- Cellular Biomedicine Group (OTCQB: CBMG) today announced that it has achieved 50% enrollment of the total projected enrollment required for its Pha...

Sony Delivers New Technology for Science to CYTO 2013

CHAMPAIGN, Ill., May 17, 2013 /PRNewswire/ -- Sony Biotechnology Inc. ("Sony") today announced the launch of the new SH800 Cell Sorter 8-well strip holder and 130um sorting chip.  Sony will...

Sony Biotechnology Inc.'s New Technology for Science Provides Researchers Results in Color

CHAMPAIGN, Ill., May 17, 2013 /PRNewswire/ -- Sony Biotechnology Inc. ("Sony") today announced the launch of the new Sony SP6800 Spectral Analyzer (SP6800).  Sony will be exhibiting and taki...

Understanding the role of dsRNA in antiviral host defense systems

Animals, insects, and plants use a variety of sensing mechanisms to detect invading pathogens such as viruses. One complex and effective antiviral defense system they share is based on recognition of...

Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells

Recent molecular studies have shown that, even when derived from a seemingly homogenous population, individual cells can exhibit substantial differences in gene expression, protein levels and phenotyp...

viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

A new tool to visualize high-dimensional single-cell data, when integrated with mass cytometry, reveals phenotypic heterogeneity of human leukemia.

Newer Whooping Cough Vaccines Fall Flat (CME/CE)

(MedPage Today) -- Youngsters who received older whole-cell whooping cough vaccines had greater protection during a recent outbreak than those who got newer acellular medications, researchers reported...

AB Science : Launch of a Phase 3 Clinical Trial in Alzheimer's Disease

PARIS -- (Marketwired) -- 05/20/13 -- Launch of a phase 3 clinical trial in the treatment of Alzheimer's disease with masitinib First patients recruited in this study AB Science SA (NYSE Euronext -...

Team finds mechanism linking key inflammatory marker to cancer

(University of Illinois at Urbana-Champaign) In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transfo...

Events [ 13 Associated Events listed on BioPortfolio]

Single Cell Analysis Summit

Select Biosciences' 4th annual Single Cell Analysis Summit 2013 will build on the overwhelming success of the previous Single Cell events.

CellTech 2014

SELECTBIO CellTech2014 will feature an integrated program of tracks designed to fully describe the latest trends in analysis of cells, cell-based assays, and high-content phenotypic assays.

Cell Culture World Congress USA

North America’s commercial cell culture event

The World Cord Blood Congress

Advancing cord blood banking & therapeutics

Stem Cells & Regenerative Medicine Congress

North America’s commercial stem cells event

World Stem Cells & Regenerative Medicine Congress 2013

Europe's largest stem cells and regenerative medicine industry conference

Stem Cells & Cell Therapy Summit

Select Biosciences' Stem Cells & Cell Therapy Summit is focused on providing an up-to-date expansive view of the current marketplace

Biopharma Asia Series 2013

Oxford Global is proud to present the Biopharma Asia Series taking place on 24th & 25th September 2013 in Singapore.

2nd Annual Cell Culture & Bioprocessing Congress 2013

175 delegates representing leading biotech companies, global pharma organisations and internationally renowned academic institutions

th Annual Next Generation Sequencing Congress 2013

Over 400 Next Generation Sequencing, Genomics, Epigenetics, Genetics, Metagenomics experts from UK, Europe and USA

Companies [ 192 Associated Companies listed on BioPortfolio]

Auxogyn, Inc.

Auxogyn is a privately held medical technology company focused on advancing women's reproductive health by applying its novel scientific and clinical knowledge of early human developmental biology to...

OncoMed Pharmaceuticals, Inc.

OncoMed Pharmaceuticals is a clinical-stage company that discovers and develops novel therapeutics targeting cancer stem cells, the cells believed to be capable of driving tumor growth, recurrence and...

GL Rapha Co., Ltd.

GL Rapha have been developing various ranges of pharmaceutical technologies specially focusing on Bio-pharmaceuticals such as recombinant proteins, synthetic peptides, and DDS bio similar based on t...

Plasticell

Plasticell is a pioneering biotechnology company that specialises in the differentiation of stem cells to obtain cell types for a range of biomedical applications. Founded in 2002, Plasticell has as...

Verastem, Inc.

Verastem, Inc. is a private biopharmaceutical company focused on discovering and developing novel drugs that selectively target cancer stem cells. Cancer stem cells are an underly...

Cell Medica

Cell Medica is a clinical stage cellular therapeutics company engaged in the development and delivery of cellular immunotherapy treatment strategies for infectious disease and can...

Etubics Corporation

Etubics Corporation, based in Seattle, Wash., is a clinical stage bio-pharmaceutical company, which has developed a proprietary platform technology consisting of a next generation...

Advanced Cell Technology, Inc.

Advanced Cell Technology, Inc. is a biotechnology company applying cellular technology in the field of regenerative medicine. For more information, visit http://www.advancedcell.c...

AmStem Corporation

AmStem Inc. is a corporation registered in the State of Nevada with offices in San Francisco, California and Seoul, Korea. The company is a world leader in the area of stem cell r...

ISICR

The International Society for Interferon and Cytokine Research (ISICR), based in Bethesda, Md., is a non-profit organization devoted to interferon, cytokine and chemokine r...

Clinical Trials [ 2969 Associated Clinical Trials listed on BioPortfolio]

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Sarcoma

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and combining chemotherapy with periphe...

Cell Lines From High-Risk Breast Tissue

Background: - Many risk factors for breast cancer have been identified, including family history, endocrine background, changes in breast tissue, cancer in one breast, radiation...

Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

This randomized phase II trial is studying how well giving tacrolimus and mycophenolate mofetil (MMF) together with or without sirolimus works in preventing acute graft-versus-host disease...

Imiquimod Cream in Treating Patients With Basal Cell Skin Cancer

RATIONALE: Biological therapies, such as imiquimod cream, work in different ways to stimulate the immune system and stop tumor cells from growing. PURPOSE: This randomized phase I trial i...

Stem Cell Collection With Ofatumumab

The goal of this clinical research study is to learn if it is possible to collect stem cells after ofatumumab and chemotherapy treatment. This study will also evaluate side-effects, number...

A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)

The main purpose of the study is to evaluate the efficacy and safety of the study drug known as prasugrel for the reduction of Vaso-Occlusive Crisis events in pediatric participants with s...

Study of OSI-774 (Tarceva) in Previously Untreated Elderly Lung Cancer Patients

The primary purpose of this study is to determine whether the drug OSI-774 is less toxic and potentially as good as or better than standard chemotherapy drugs, when given to subjects with...

Vemurafenib, Cetuximab, and Irinotecan in Advanced Solid Cancers

The goal of this clinical research study is to find the highest tolerable dose of vemurafenib that can be given in combination with cetuximab and irinotecan to patients with advanced cance...

Melphalan and Amifostine Followed By One or Two Autologous or Syngeneic Stem Cell Transplants and Maintenance Therapy in Treating Patients With Stage II or Stage III Multiple Myeloma

RATIONALE: Drugs used in chemotherapy, such as melphalan, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Chemopro...

Bevacizumab and Combination Chemotherapy in Treating Patients With Peripheral T-Cell Lymphoma or Natural Killer Cell Neoplasms

RATIONALE: Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and he...

Videos

Nursing Students Respiratory Drugs 1 trick to Learning 100%

"82% or Higher on Your Next Nursing Test GUARANTEED!" SIMPLENURSING.com FREE DRUG CARDS @ SimpleNursing.com 100% knowledge of Respiratory Drugs Nursing stude...

Medical and Biotech [MESH] Definitions

Chromosomes, Plant

Complex nucleoprotein structures which contain the genomic DNA and are part of the CELL NUCLEUS of PLANTS.

Spectral Karyotyping

The simultaneous identification of all chromosomes from a cell by fluorescence in situ hybridization (IN SITU HYBRIDIZATION, FLUORESCENCE) with chromosome-specific florescent probes that are discerned by their different emission spectra.

Chromosomes, Mammalian

Complex nucleoprotein structures which contain the genomic DNA and are part of the CELL NUCLEUS of MAMMALS.

Stem Cell Transplantation

The transfer of STEM CELLS from one individual to another within the same species (TRANSPLANTATION, HOMOLOGOUS) or between species (XENOTRANSPLANTATION), or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). The source and location of the stem cells determines their potency or pluripotency to differentiate into various cell types.

Periplasmic Proteins

Proteins found in the PERIPLASM of organisms with cell walls.

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