Meningococcal Conjugates Vaccine - Biotech, Pharma and Life Science Channel

11:03 EST 6th March 2015 | BioPortfolio

PubMed Articles [1919 Associated PubMed Articles listed on BioPortfolio]

Evaluating potential T-cell epitope peptides for detecting HIV-specific T cell responses in a highly diverse HIV-1 epidemic from Cameroon.

HIV genetic diversity is a major obstacle for vaccine development. To define whether potential T-cell epitope (PTE) peptide usage improves the detection of T cell responses in a highly diverse HIV-1 e...

Update: Influenza Activity - United States, September 28, 2014-February 21, 2015.

Influenza activity in the United States began to increase in mid-November, remained elevated through February 21, 2015, and is expected to continue for several more weeks. To date, influenza A (H3N2) ...

Inhibition of Cancer Cell Proliferation and Breast Tumor Targeting of pHLIP-Monomethyl Auristatin E Conjugates.

Localized delivery is vital for the successful development of novel and effective therapeutics for the treatment of cancer. The targeting and delivery described herein is based on the pH(Low) Insertio...

Peptide-Nanoparticle Ligation Mediated by Cutinase Fusion for the Development of Cancer Cell-Targeted Nanoconjugates.

The relationship between the positioning of ligands on the surface of nanoparticles and the structural features of nanoconjugates has been underestimated for a long time albeit of primary importance t...

Conformational Dynamics and Antigenicity in the Disordered Malaria Antigen Merozoite Surface Protein 2.

Merozoite surface protein 2 (MSP2) of Plasmodium falciparum is an abundant, intrinsically disordered protein that is GPI-anchored to the surface of the invasive blood stage of the malaria parasite. Re...

Generation of Influenza Virus from Avian Cells Infected by Salmonella Carrying the Viral Genome.

Domestic poultry serve as intermediates for transmission of influenza A virus from the wild aquatic bird reservoir to humans, resulting in influenza outbreaks in poultry and potential epidemics/pandem...

One step synthesis of quantum dot-magnetic nanoparticle heterodimers for dual modal imaging applications.

Dual modal nanoprobes are promising tools for accurately detecting target molecules as part of the diagnosis of diseases including cancers. We have explored a new dual modal bioimaging probe that is c...

Site of Reactivity Models Predict Molecular Reactivity of Diverse Chemicals with Glutathione.

Drug toxicity is often caused by electrophilic reactive metabolites that covalently bind to proteins. Consequently, the quantitative strength of a molecule's reactivity with glutathione (GSH) is a fre...

Correction: Determinants of Acceptance and Subsequent Uptake of the HPV Vaccine in a Cohort in Eldoret, Kenya.

[This corrects the article DOI: 10.1371/journal.pone.0109353.].

Emergency Postexposure Vaccination With Vesicular Stomatitis Virus-Vectored Ebola Vaccine After Needlestick.

Safe and effective vaccines and drugs are needed for the prevention and treatment of Ebola virus disease, including following a potentially high-risk exposure such as a needlestick.

News Articles [2880 Associated News Articles listed on BioPortfolio]

State Highlights: MassHealth Savings Key To Balancing State Budget; Calif. Chiropractors Lobby Against Bill Ending Vaccine Exemptions

A selection of health policy stories from Massachusetts, California, Wisconsin, Utah, Georgia, Wyoming, Iowa and Colorado.

WHO reports launch of Merck/NewLink VSV-EBOV vaccine trial in Guinea

The World Health Organization has reported the launch trials of the VSV-EBOV vaccine for Ebola in Guinea,…

New Technologies, New Vaccines Conference Provides Opportunity to Share New Advancements in Combating Emerging Infectious Diseases, Including Ebola

More than 100 scientists, business leaders and regulatory agency representatives from around the world will convene at the Hotel DuPont in Wilmington, DE from March 22–25, 2015 ...

2015’s biggest health story was broken by a doctor, not a reporter

Measles Makes an Unwelcome Visit to Disneyland Health Alert after Disneyland linked to measles outbreak Mickey, Minnie and measles for nine Disneyland tourists The headlines from January 7th and 8th t...

Opdivo gains new US lung cancer licence

Adds to Bristol-Myers Squibb’s therapeutic vaccine’s melanoma indication

Pfizer's Pneumonia Vaccine Prevenar Okayed for Adults in EU

Pfizer receives European approval for new indication for Prevenar 13 for the prevention of vaccine-type pneumococcal pneumonia in adults

Microbix Announces Annual and Special Meeting Voting Results

TORONTO, ONTARIO -- (Marketwired) -- 03/06/15 -- Microbix Biosystems Inc. (TSX: MBX) ("Microbix" or the "Company"), an innovator of biological products and technologies, announces the results of the...

Gates Foundation gets behind mRNA vaccinework – contributes $52M to CureVac in its biggest biotech deal yet

RNA drug discovery just got a huge vote of confidence from the Bill and Melinda Gates Foundation. One of the biggest priorities of The Bill & Melinda Gates Foundation is vaccine...

WHO to Begin Large-Scale Testing of Ebola Vaccine in Guinea

LONDON (AP) — The World Health Organization will start large-scale testing of an experimental Ebola vaccine in Guinea on Saturday to see how effective it might be in preventing future outbreaks of t...

Gates Foundation and CureVac Collaborate to Accelerate the Development of Transformative Vaccine Technology

The Bill & Melinda Gates Foundation and CureVac today announced that the foundation has made a commitment to invest $52 million in CureVac, a leading clinical-stage biopharmaceutical company speci...

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Companies [100 Associated Companies listed on BioPortfolio]

The Vaccine & Gene Therapy Institute of Florida (VGTI Florida)

Targovax

Targovax was started in October 2010 to develop TG01, a vaccine targeting pancreatic cancer. TG01 is based on research from The Radium Hospital and Norsk Hydro in the end of the 9...

Genocea Biosciences

Genocea Biosciences was founded in 2006 to commercialize key breakthroughs in vaccine discovery and development. The Company’s proprietary T cell-directed antigen disc...

The Vaccine & Gene Therapy Institute of Florida

ImmusanT Inc.

ImmusanT is a privately-held biotechnology company focused on restoring tolerance to gluten in celiac disease by harnessing new discoveries in immunology that aim to improve diagn...

Affinivax Inc.

Affinivax is advancing a next generation conjugate vaccine technology platform to enable the development of vaccines that provide the highest level of protection against challengi...

Mucosis B.V.

Mucosis B.V. (Mucosis) is a clinical-stage biotechnology company using a proprietary technology platform to develop next-generation needle-free human vaccines for infectious disea...

Vaxart, Inc.

Vaxart is a privately owned company developing oral recombinant vaccines based on its proprietary delivery platform. The Vaxart platform is suitable to deliver any protein vaccine...

ADC Therapeutics

ADC Therapeutics sarl (ADCT) is a Swiss-based oncology drug development company that specializes in the development of proprietary Antibody Drug Conjugates (ADCs) targeting major ...

Mucosis

Mucosis B.V. is a clinical-stage biotechnology company developing novel vaccines on its proprietary Mimopath® platform technology. The Mimopath® platform is being studied fo...

Clinical Trials [2139 Associated Clinical Trials listed on BioPortfolio]

Safety and Tolerability Study for the Pneumococcal Conjugate Vaccine V114 Versus Prevnar™ (V114-001 EXT1)(COMPLETED)

This study is being conducted to evaluate the safety, tolerability, and immunogenicity of 15-valent Pneumococcal conjugate vaccine (V114) compared to Prevnar™ in healthy adults and toddl...

Evaluation of Immunogenicity and Safety of Two 2-dose Human Papillomavirus (HPV) Vaccine Schedules in 9-14 Year Old Girls

This study has been designed to evaluate the immunogenicity and safety of GSK Biologicals' HPV-16/18 vaccine when administered according to alternative 2-dose schedules (0,6 months and 0,1...

Training Study to Characterize Biomarkers to Chickenpox and Yellow Fever Vaccines

It is thought that vaccines trigger innate inflammatory responses to induce antigenspecific adaptive immunity (the desired effect), but excessive inflammation may lead to serious inflammat...

PANVAC-V and PANVAC-F Vaccines Plus Sargramostim to Treat Advanced Cancer

Background: - Many cancers produce two proteins, carcinoembryonic antigen (CEA) and mucin-1 (MUC-1). - The PANVAC-V priming vaccine and PANVAC-F boosting vaccine contain human gene...

A Study to Evaluate the Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Quadrivalent Influenza Candidate Vaccine (GSK2321138A) Manufactured Using a New Process in Adults and Children

The purpose of this trial is to demonstrate the acceptable safety profile and the immunological non-inferiority of the FLU D-QIV vaccine manufactured with this investigational process (FLU...

Trial of the Safety and Immunogenicity of an Oral, Replicating Ad26 Vectored HIV-1 Vaccine

This is a dose escalation study to test the safety and immunogenicity of an oral HIV-1 vaccine.

Maternal Tdap Immunization in Guatemala

Maternal immunization with tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) is a potential strategy to protect young infants against pertussis before they ...

Pilot Trial of a WT-1 Analog Peptide Vaccine in Patients With Myeloid Neoplasms

The purpose of this study is to determine whether the WT-1 vaccine causes an immune response and is safe. The WT-1 vaccine is made up of protein pieces that the patient's immune system can...

Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Combined Measles-mumps-rubella (MMR) Vaccine in Subjects Four to Six Years of Age

The purpose of this study is to support licensure of GSK Biologicals' MMR vaccine (Priorix®) in the US by generating immunogenicity and safety data in contrast to the US standard of care,...

Comparison of Dendritic Cells Versus Montanide as Adjuvants in a Melanoma Vaccine

In this study, a melanoma vaccine (5 melanoma peptides) is given with either Montanide or dendritic cells as adjuvants. This randomized trial will establish the safety of both vaccines and...

Medical and Biotech [MESH] Definitions

A combined vaccine used to prevent infection with diphtheria and tetanus toxoid. This is used in place of DTP vaccine (DIPHTHERIA-TETANUS-PERTUSSIS VACCINE) when PERTUSSIS VACCINE is contraindicated.

A live vaccine containing attenuated poliovirus, types I, II, and III, grown in monkey kidney cell tissue culture, used for routine immunization of children against polio. This vaccine induces long-lasting intestinal and humoral immunity. Killed vaccine induces only humoral immunity. Oral poliovirus vaccine should not be administered to immunocompromised individuals or their household contacts. (Dorland, 28th ed)

A bacterial vaccine for the prevention of brucellosis in man and animal. Brucella abortus vaccine is used for the immunization of cattle, sheep, and goats.

A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had mumps or been immunized with live mumps vaccine. Children are usually immunized with measles-mumps-rubella combination vaccine.

A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had measles or been immunized with live measles vaccine and have no serum antibodies against measles. Children are usually immunized with measles-mumps-rubella combination vaccine. (From Dorland, 28th ed)

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