Meningococcal Conjugates Vaccine - Biotech, Pharma and Life Science Channel

02:32 EDT 25th April 2015 | BioPortfolio

PubMed Articles [1951 Associated PubMed Articles listed on BioPortfolio]

Protective Antibodies against Placental Malaria and Poor Outcomes during Pregnancy, Benin.

Placental malaria is caused by Plasmodium falciparum-infected erythrocytes that bind to placental tissue. Binding is mediated by VAR2CSA, a parasite antigen coded by the var gene, which interacts with...

Correction for kim et Al., development of an adenovirus-based respiratory syncytial virus vaccine: preclinical evaluation of efficacy, immunogenicity, and enhanced disease in a cotton rat model.

Understanding How Different Recruitment Strategies Impact Parent Engagement With an iPad-Based Intervention to Provide Personalized Information About Adolescent Vaccines.

Inadequate provider time for addressing parents' questions and concerns about adolescent vaccines is a barrier to vaccine utilization. We sought to determine how different recruitment strategies impac...

Strategies for Increasing Adolescent Immunizations in Diverse Ethnic Communities.

We sought to identify attitudes and knowledge of adolescent vaccination recommendations for tetanus, diphtheria, and acellular pertussis (Tdap); quadrivalent meningococcal conjugate (MCV4); and human ...

Increasing Human Papillomavirus Vaccine Initiation Among Publicly Insured Florida Adolescents.

We evaluated the feasibility of a multilevel intervention to increase the human papillomavirus (HPV) vaccine initiation among adolescents.

Keen on Teen Vaccines: Improvement of Adolescent Vaccine Coverage in Rural North Carolina.

To improve adolescent immunization coverage in a rural North Carolina county.

Seroprevalence and Seroincidence of Herpes Simplex Virus (2006-2010), Syphilis (2006-2010), and Vaccine-Preventable Human Papillomavirus Subtypes (2000-2010) Among US Military Personnel.

Sexually transmitted infections have historically been burdensome in military populations. We describe the seroprevalence and seroincidence of vaccine-preventable human papillomavirus (VP-HPV) subtype...

Immunogenicity and Safety of Meningococcal C Conjugate Vaccine in Children and Adolescents Infected and Uninfected with HIV in Rio de Janeiro, Brazil.

We aimed to evaluate the Meningococcal (Neisseria meningitidis) C conjugated (MCC) vaccine seroconversion and adverse events (AEs) in HIV-infected and HIV-uninfected children and adolescents in Rio de...

Functionalization of cobalt porphyrin-phospholipid bilayers with his-tagged ligands and antigens.

Methods to attach polypeptides to lipid bilayers are often indirect and ineffective, and can represent a substantial bottleneck in the formation of functionalized lipid-based materials. Although the p...

Tracking Progress Toward Polio Eradication - Worldwide, 2013-2014.

Global efforts to eradicate polio began in 1988 and have been successful in all but two of the six World Health Organization (WHO) regions. Within these two regions (African and Eastern Mediterranean)...

News Articles [2818 Associated News Articles listed on BioPortfolio]

Large‐scale adenovirus and poxvirus‐vectored vaccine manufacturing to enable clinical trials

Efforts to make vaccines against infectious diseases and immunotherapies for cancer have evolved to utilize a variety of heterologous expression systems such as viral vectors. These vectors are often ...

The stage‐specific in vitro efficacy of a malaria antigen cocktail provides valuable insights into the development of effective multi‐stage vaccines

Multicomponent vaccines targeting different stages of Plasmodium falciparum represent a promising, holistic concept towards better malaria vaccines. Additionally, an effective vaccine candidate should...

Three concerns derail Biovest's cancer vaccine approval hopes

Lympreva had been filed for approval to maintain the absence of cancer symptoms when used in combination with granulocyte macrophage colony-stimulating factor (GM-CSF) in patients with follicular non-...

Malaria vaccine is partly effective in young children, study shows

The first malaria vaccine to reach phase III clinical testing is partly effective against clinical disease in young children in Africa, results reported in the Lancet have shown.1The study included......

World’s First Malaria Vaccine Could Be Rolled Out By End of Year

(New Scientist) – A disease that kills around 1300 children each day in sub-Saharan Africa may shortly be on the run, thanks to promising results from what could become the world’s first v...

A Mother's Love in Action at 'Ground Zero': National Patient Advocacy Group Comes to Oregon for World Meningitis Day and National Infant Immunization Week

SALEM, Ore., April 24, 2015 /PRNewswire/ -- Frankie Milley founded Meningitis Angels when her teenage son Ryan died. Portland, Ore. dad Scott Parkhurst joined the fight last year after losing his...

LA Times: Senate committe OKs bill that would remove vaccine exemptions in California

Antoinette AlexanderA key Senate committee has approved a bill that would remove vaccine exemptions for school children in California, according to the Los Angeles Times. read more

Malaria Vaccine Found Effective in Infants, Young Children (CME/CE)

(MedPage Today) -- Efficacy dropped sharply after 48 months, however, without a booster.

Malaria vaccine candidate RTS,S has demonstrated efficacy over 3-4 years of follow-up

Phase III trial results of the RTS,S vaccine candidate show that it helped protect children from clinical malaria for at least 3 years after vaccination... The post Malaria vaccine candidate RTS,S has...

Malaria Vaccine is a Letdown But Could Still Reduce Cases

LONDON (AP) — The world's leading malaria vaccine candidate appears to be a disappointment, with final study results showing it doesn't work very well and that initial protection fades over time. ...

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Companies [100 Associated Companies listed on BioPortfolio]

Aduro BioTech, Inc.

Aduro BioTech is a clinical-stage immunotherapy company with a platform technology for therapeutic and prophylactic vaccines for cancer and infectious diseases. The platform of at...

ADC Therapeutics Sarl

ADC Therapeutics (ADCT) is a Swiss-based oncology drug development company that specializes in the development of proprietary Antibody Drug Conjugates (ADCs) targeting major cance...

The Vaccine & Gene Therapy Institute of Florida (VGTI Florida)

Targovax

Targovax was started in October 2010 to develop TG01, a vaccine targeting pancreatic cancer. TG01 is based on research from The Radium Hospital and Norsk Hydro in the end of the 9...

Genocea Biosciences

Genocea Biosciences was founded in 2006 to commercialize key breakthroughs in vaccine discovery and development. The Company’s proprietary T cell-directed antigen disc...

The Vaccine & Gene Therapy Institute of Florida

ImmusanT Inc.

ImmusanT is a privately-held biotechnology company focused on restoring tolerance to gluten in celiac disease by harnessing new discoveries in immunology that aim to improve diagn...

Affinivax Inc.

Affinivax is advancing a next generation conjugate vaccine technology platform to enable the development of vaccines that provide the highest level of protection against challengi...

Mucosis B.V.

Mucosis B.V. (Mucosis) is a clinical-stage biotechnology company using a proprietary technology platform to develop next-generation needle-free human vaccines for infectious disea...

Vaxart, Inc.

Vaxart is a privately owned company developing oral recombinant vaccines based on its proprietary delivery platform. The Vaxart platform is suitable to deliver any protein vaccine...

Clinical Trials [2185 Associated Clinical Trials listed on BioPortfolio]

Exploration of the Biologic Basis for Underperformance of Oral Polio and Rotavirus Vaccines in Bangladesh

Oral polio and rotavirus vaccines are significantly less effective in children living in the developing world. Tropical enteropathy, which is associated with intestinal inflammation, decre...

Survey for Usage Rates of Pertussis Vaccines in the State of Wisconsin

The purpose of this study is to determine during the course of 5 years, the patterns of pertussis vaccine usage by brand and dose among children birth through 59 months of age who have rec...

Safety and Immunogenicity of Two Doses of H5N1 Influenza Vaccine in Children

Evaluate Safety, Tolerability and Immune response of adjuvanted H5N1 cell culture derived influenza vaccine in children.

H7N9 Mix and Match With MF59 in Healthy Elderly Persons

This is a Phase II randomized, partially-blinded, controlled trial in 360 (up to 600) males and females, 65 years of age and older, who are in good health and meet all eligibility criteria...

Multicenter Pilot Study Evaluating the Immunogenicity of an Innovative Pneumococcal Vaccination Strategy in Splenectomized Adults

Evaluate the immunogenicity of an innovative pneumococcal vaccination strategy in splenectomized adults comprising 1 dose of Prevenar13® conjugate vaccine (PCV) at M0 followed by 1 dose o...

Duration of Long-term Immunity After Hepatitis B Virus Immunization

Background: - The hepatitis B vaccine has been shown to be safe and effective in preventing transmission of the hepatitis B virus. Response rates to the initial three doses of the...

A Study of VGX-3100 and INO-9012 DNA Vaccine With Electroporation in Patients With Cervical Cancer

This is an open-label study to evaluate the safety, tolerability, and immunogenicity of VGX-3100 and INO-9012 DNA vaccines delivered by Electroporation to female subjects with HPV-16 or 1...

A Safety and Immune Response Study of 2 Experimental HIV Vaccines

The HIV Vaccine Trials Network (HVTN) is doing a study to test a new HIV vaccine combination. HIV is the virus that causes AIDS. About 252 people will take part in this study at multiple ...

ProQuad Dose Selection Study (V221-011)(COMPLETED)

A Study comparing three different doses of ProQuad to concomitant administration of M-M-R II and PUVV (Process Upgrade Varicella Vaccine) vaccines.

Vaccination of High Risk Breast Cancer Patients

Objective - Determine the safety and tolerability of a peptide mimotope-based vaccine upon immunization of breast cancer subjects.

Medical and Biotech [MESH] Definitions

A combined vaccine used to prevent infection with diphtheria and tetanus toxoid. This is used in place of DTP vaccine (DIPHTHERIA-TETANUS-PERTUSSIS VACCINE) when PERTUSSIS VACCINE is contraindicated.

A live vaccine containing attenuated poliovirus, types I, II, and III, grown in monkey kidney cell tissue culture, used for routine immunization of children against polio. This vaccine induces long-lasting intestinal and humoral immunity. Killed vaccine induces only humoral immunity. Oral poliovirus vaccine should not be administered to immunocompromised individuals or their household contacts. (Dorland, 28th ed)

A bacterial vaccine for the prevention of brucellosis in man and animal. Brucella abortus vaccine is used for the immunization of cattle, sheep, and goats.

A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had mumps or been immunized with live mumps vaccine. Children are usually immunized with measles-mumps-rubella combination vaccine.

A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had measles or been immunized with live measles vaccine and have no serum antibodies against measles. Children are usually immunized with measles-mumps-rubella combination vaccine. (From Dorland, 28th ed)

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