Meningococcal Conjugates Vaccine - Biotech, Pharma and Life Science Channel

17:16 EST 21st December 2014 | BioPortfolio

PubMed Articles [1833 Associated PubMed Articles listed on BioPortfolio]

Design, Synthesis, Antiviral Activity, and Pre-Formulation Development of Poly-L-Arginine-Fatty Acyl Derivatives of Nucleoside Reverse Transcriptase Inhibitors.

The objective of this work was to design conjugates of anti-HIV nucleosides conjugated with fatty acids and cell-penetrating poly-L-arginine (polyArg) peptides. Three conjugates of polyArg cell-penetr...

Determination of α- and β-boldenone sulfate, glucuronide and free forms, and androstadienedione in bovine urine using immunoaffinity columns clean-up and liquid chromatography tandem mass spectrometry analysis.

The debate about the origins of boldenone in bovine urine is ongoing for two decades in Europe. Despite the fact that its use as a growth promoter has been banned in the European Union (EU) since 1981...

Systematic review and meta-analysis of the effectiveness of commercially available vaccines against bovine herpesvirus, bovine viral diarrhea virus, bovine respiratory syncytial virus, and parainfluenza type 3 virus for mitigation of bovine respiratory disease complex in cattle.

Objective-To evaluate and analyze data from controlled studies on the effectiveness of vaccinating cattle with commercially available viral antigen vaccines for mitigation of the effects of bovine res...

Proteomics Characterization of Tick-Host-Pathogen Interactions.

Ticks are blood-feeding arthropod ectoparasites of wild and domestic animals that transmit disease-causing pathogens to humans and animals worldwide and a good model for the characterization of tick-h...

Post-acquisition analysis of untargeted accurate mass quadrupole time-of-flight MS(E) data for multiple collision-induced neutral losses and fragment ions of glutathione conjugates.

Analytical methods to assess glutathione (GSH) conjugate formation based on mass spectrometry usually take advantage of the specific fragmentation behavior of the glutathione moiety. However, most met...

Detailed characterization of antibody responses against HIV-1 group M consensus gp120 in rabbits.

BackgroundWe recently reported induction of broadly neutralizing antibodies (bnAbs) against multiple HIV-1 (human immunodeficiency virus type 1) isolates in rabbits, albeit weak against tier 2 viruses...

Quantum yield measurements of light-induced H2 generation in a photosystem I-FeFe-H 2ase nanoconstruct.

The quantum yield for light-induced H2 generation was measured for a previously optimized bio-hybrid cytochrome c 6-crosslinked PSIC13G-1,8-octanedithiol-[FeFe]-H2aseC97G (PSI-H2ase) nanoconstruct. Th...

Cost-Effectiveness Evaluation of the 10-Valent Pneumococcal Non-typeable Haemophilus influenzae Protein D Conjugate Vaccine and 13-Valent Pneumococcal Vaccine in Japanese Children.

Diseases caused by Streptococcus pneumoniae represent a major public health problem. The purpose of this study was to compare, in the Japanese context, the projected health benefits, costs and cost-ef...

Analysis of Bordetella pertussis clinical isolates circulating in European countries during the period 1998-2012.

Despite more than 50 years of vaccination, pertussis is still an endemic disease, with regular epidemic outbreaks. With the exception of Poland, European countries have replaced whole-cell vaccines (...

Alpha-galactosylceramide enhances protective immunity induced by DNA vaccine of the SAG5D gene of Toxoplasma gondii.

BackgroundToxoplasmosis caused by the intracellular parasite Toxoplasma gondii (T. gondii) is a global epidemic parasitic disease. DNA vaccines play an important role in preventing the spread of toxop...

News Articles [2889 Associated News Articles listed on BioPortfolio]

Week in Review: China's Neusoft Raises $610 Million for Life Science Subsidiaries

Neusoft, a China software and medical device company, raised $610 million from investors to support its medical imaging and mobile health divisions; SciClone Pharma in-licensed China marketing rights ...

antibodies from llamas might help in the fight against HIV/AIDS

Most vaccines work by inducing an immune response characterized by neutralizing antibodies against the respective pathogen. An effective HIV vaccine has remained elusive so far, but researchers have c...

AMMS-CanSino to Start Clinical Trial of China Ebola Vaccine

A China-discovered Ebola vaccine, developed jointly by the Bioengineering Institute of China's Academy of Military Medical Sciences (AMMS) and Tianjin CanSino Biotechnology, has been approved to begin...

GeneSegues gets gov’t contract to develop a topical vaccine for Venezuelan encephalitis

Minneapolis vaccine developer GeneSegues Therapeutics has a new government contract to develop a DNA vaccine against Venezuelan equine encephalitis virus – an infectious disease that has the p...

SynAffix closes Series A round

Aravis, BioGeneration Ventures, MS Ventures, and BOM Capital provided antibody-drug conjugates (ADC) firm SynAffix BV with an undisclosed amount of Series A funding. Representatives from Aravis, BioGe...

High-Dose Vaccine May Improve Influenza Protection in Elderly

Frail and elderly adults are especially vulnerable to influenza. They also have a weakened ability to mount an immune response to the traditional influenza vaccine. Medscape Medical News

Harbour Antibodies Announces First U.S. Patent for Novel Transgenic Mouse Antibody Technology for Next Generation Therapeutic Antibody Discovery

Patent Covering “Heavy Chain Only” Antibody Platform Enables Discovery of Products Not Achievable with Conventional Antibody Platforms Harbour Antibodies BV announced the ...

Chinese Ebola vaccine enters clinical trials

Biospectrum The country's regulators have approved a domestically developed vaccine for human clinical trials [Read mor...

Wistar Institute CEO steps down after 13 years

Under his watch, Wistar Institute raised nearly $80 million and added a new research center for cancer, immunology research and vaccine development in September, but CEO Russel Kaufman is stepping...

Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines

Immunomic Therapeutics, Inc. and Bioject have entered into an agreement for ITI to use Bioject’s Biojector®-2000 needle-free injection device with its LAMP™ vaccine platform. This collaborati...

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Companies [99 Associated Companies listed on BioPortfolio]

Genocea Biosciences

Genocea Biosciences was founded in 2006 to commercialize key breakthroughs in vaccine discovery and development. The Company’s proprietary T cell-directed antigen disc...

The Vaccine & Gene Therapy Institute of Florida

ImmusanT Inc.

ImmusanT is a privately-held biotechnology company focused on restoring tolerance to gluten in celiac disease by harnessing new discoveries in immunology that aim to improve diagn...

Affinivax Inc.

Affinivax is advancing a next generation conjugate vaccine technology platform to enable the development of vaccines that provide the highest level of protection against challengi...

Mucosis B.V.

Mucosis B.V. (Mucosis) is a clinical-stage biotechnology company using a proprietary technology platform to develop next-generation needle-free human vaccines for infectious disea...

Vaxart, Inc.

Vaxart is a privately owned company developing oral recombinant vaccines based on its proprietary delivery platform. The Vaxart platform is suitable to deliver any protein vaccine...

ADC Therapeutics

ADC Therapeutics sarl (ADCT) is a Swiss-based oncology drug development company that specializes in the development of proprietary Antibody Drug Conjugates (ADCs) targeting major ...

Mucosis

Mucosis B.V. is a clinical-stage biotechnology company developing novel vaccines on its proprietary Mimopath® platform technology. The Mimopath® platform is being studied fo...

Igenica Biotherapeutics, Inc.

Igenica Biotherapeutics is focused on the discovery and development of antibodies and antibody-drug conjugates (ADCs) for the treatment of cancer. Igenica is the only biotherapeut...

Shoo the Flu

The flu, also called influenza, is a contagious disease that spreads by coughing, sneezing and close contact. Flu symptoms include fever/chills, sore throat, muscle aches, fatigue...

Clinical Trials [2113 Associated Clinical Trials listed on BioPortfolio]

Vaccine Therapy, GM-CSF, and Interferon Alfa-2b in Treating Patients With Locally Advanced or Metastatic Cancer That Expresses Carcinoembryonic Antigen (CEA)

This phase I trial is studying the side effects and best dose of interferon alfa-2b when given together with vaccine therapy and GM-CSF in treating patients with locally advanced or metast...

Induction of Donor-Specific Tolerance in Recipients of Live Donor Stem Cell Infusion (Compassionate Use)

Four subjects were treated under compassionate use provisions under this study with facilitating cell therapy (FCRx) product manufactured using the CliniMACS (Miltenyi Biotec) device, rath...

A Phase I Study To Evaluate The Antitumor Activity And Safety Of AVX901

HER2 is a protein that is over expressed in 20-30% of breast cancers. It is also found associated with lung, gastric, ovarian, and pancreatic cancers. Although there are existing therapi...

Additional 6-Month Safety Follow-up After Completion of Precursor Study 880801

The purpose of this study is to verify the long-term safety of a 2.5 µg, adjuvanted (aluminium hydroxide) dose of Ross River Virus (RRV) vaccine.

Safety and Blood Donations in Adults Vaccinated With rMenB+OMV NZ.

The purpose of this trial is to assess the safety of a Meningococcal Group B Vaccine and to collect blood donation. Sera panel obtained from blood donations will be used as a control to me...

SOP Toolkit in Diverse Practices Implemented & Tested With RE-AIM

The purpose of this study is to test whether or not the 4 Pillars Toolkit increases adult Influenza, pneumococcal polysaccharide vaccine (PPSV), tetanus, adult diphtheria and acellular per...

Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Influenza Vaccine(s) GSK3277510A and GSK3277509A in Adults 18 to 60 Years of Age

The purpose of this study is to evaluate the safety and immunogenicity of different formulations of GSK Biologicals' H7N9 influenza vaccine in subjects 18 to 60 years of age.

Safety of Sublingual dmLT for ETEC

A Phase 1 dose escalating study of ETEC candidate vaccine to determine safety and immunogenicity of a multi-dose regimen in healthy adult volunteers. The study will be conducted at Cincinn...

Cervical Intraepithelial Neoplasm (CIN) in Women (Gardasil)(V501-015)

The primary purpose of the study is to determine if Gardasil (V501) an investigational vaccine with 4 components is able to prevent cervical cancer.

Vaccine Therapy and Sargramostim in Treating Patients With Pancreas Cancer That Cannot Be Removed By Surgery

This phase I trial studies the side effects and best dose of vaccine therapy when given together with sargramostim in treating patients with locally advanced or metastatic pancreatic cance...

Medical and Biotech [MESH] Definitions

A combined vaccine used to prevent infection with diphtheria and tetanus toxoid. This is used in place of DTP vaccine (DIPHTHERIA-TETANUS-PERTUSSIS VACCINE) when PERTUSSIS VACCINE is contraindicated.

A live vaccine containing attenuated poliovirus, types I, II, and III, grown in monkey kidney cell tissue culture, used for routine immunization of children against polio. This vaccine induces long-lasting intestinal and humoral immunity. Killed vaccine induces only humoral immunity. Oral poliovirus vaccine should not be administered to immunocompromised individuals or their household contacts. (Dorland, 28th ed)

A bacterial vaccine for the prevention of brucellosis in man and animal. Brucella abortus vaccine is used for the immunization of cattle, sheep, and goats.

A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had mumps or been immunized with live mumps vaccine. Children are usually immunized with measles-mumps-rubella combination vaccine.

A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had measles or been immunized with live measles vaccine and have no serum antibodies against measles. Children are usually immunized with measles-mumps-rubella combination vaccine. (From Dorland, 28th ed)

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