Meningococcal Conjugates Vaccine - Biotech, Pharma and Life Science Channel

08:41 EDT 20th August 2014 | BioPortfolio

PubMed Articles [1833 Associated PubMed Articles listed on BioPortfolio]

Effect and mechanisms of curdlan sulfate on inhibiting HBV infection and acting as an HB vaccine adjuvant.

In this study, the effect and mechanisms of curdlan sulfate (CS3) on hepatitis B virus (HBV) infection and promoting immune response of the mice immunized with recombinant hepatitis B surface protein...

Drug delivery vehicles on a nano-engineering perspective.

Nanoengineered drug delivery systems (nDDS) have been successfully used as clinical tools for not only modulation of pharmacological drug release profile but also specific targeting of diseased tissue...

Pneumococcal meningitis: A 12 year experience in a children's hospital prior to the universal immunization with a conjugate vaccine.

Introduction. Pneumococcal meningitis is causedby Streptococcuspneumoniae and hashigh morbidity and mortality rates. The objective of this study was to identify the epidemiological and clinical charac...

Pertussis seroprevalence in adults, post-partum women and umbilical cord blood.

Pertussis is a vaccine-preventable disease that affects people of all ages. Young adults who have lost their immunity to pertussis are the major source of infection in infants. Given the steady increa...

Preparation of Triple-Negative Breast Cancer Vaccine through Electrofusion with Day-3 Dendritic Cells.

Dendritic cells (DCs) are professional antigen-presenting cells (APCs) in human immune system. DC-based tumor vaccine has met with some success in specific malignancies, inclusive of breast cancer. In...

Is the "3+3" dose escalation phase 1 clinical trial design suitable for therapeutic cancer vaccine development? A recommendation for alternative design.

Purpose: Phase 1 clinical trials are generally conducted to identify the maximum tolerated dose (MTD) or the biologically active dose (BAD) using a traditional dose escalation design. This design may...

DECORATION OF OUTER MEMBRANE VESICLES WITH MULTIPLE ANTIGENS USING AN AUTOTRANSPORTER APPROACH.

Outer membrane vesicles (OMVs) are spherical nanoparticles that naturally shed from Gram-negative bacteria. They are rich in immunostimulatory proteins and lipopolysaccharide but do not replicate, whi...

Optimization of Storage and Stability of Camel Liver Glutathione S-Transferase.

Glutathione S-transferases (GSTs) are multifunctional enzymes and play an important role in cellular detoxification. Besides this, GSTs act as cytosolic carrier proteins which bind hydrophobic compoun...

Threaded macromolecules as a versatile framework for biomaterials.

Polyrotaxanes (PRXs) are a class of supramolecular threaded macromolecules, in which cyclic molecules are threaded onto the main- or side-chain of polymers. To date, various studies have been conducte...

An Attenuated Herpes Simplex Virus Type 1 (HSV1) Encoding the HIV-1 Tat Protein Protects Mice from a Deadly Mucosal HSV1 Challenge.

Herpes simplex virus types 1 and 2 (HSV1 and HSV2) are common infectious agents in both industrialized and developing countries. They cause recurrent asymptomatic and/or symptomatic infections, and li...

News Articles [2379 Associated News Articles listed on BioPortfolio]

New Research Study Finds Vaccine Stops Mesothelioma in Lab Mice, According to Surviving Mesothelioma Website

Hong Kong researchers have found that a vaccine designed to alter DNA can protect mice from mesothelioma and even cure mice that have the disease. Raleigh, NC (PRWEB) August 20, 2014 Doctors at the U...

Student seeks to improve pneumonia vaccines

Almost a million Americans fall ill with pneumonia each year. Nearly half of these cases require hospitalization, and 5-7 percent are fatal. Current vaccines provide protection against some strains of...

Shantha Biotechnics Limited - Product Pipeline Review - 2014

Recently added to the BioPortfolio report store, Shantha Biotechnics Limited - Product Pipeline Review - 2014 is a new report from Global Markets Direct published on 2014-07-30. This 22-page report i...

Adiga Life Sciences Inc. - Product Pipeline Review - 2014

Recently added to the BioPortfolio report store, Adiga Life Sciences Inc. - Product Pipeline Review - 2014 is a new report from Global Markets Direct published on 2014-08-13. This 16-page report is a...

Varicella Zoster (HHV-3) Infections - Pipeline Review, H2 2014

Recently added to the BioPortfolio report store, Varicella Zoster (HHV-3) Infections - Pipeline Review, H2 2014 is a new report from Global Markets Direct published on 2014-07-30. This 51-page report...

Researchers use optical tweezers to measure how strongly parasites adhere to red blood cells

Malaria is a life-threatening disease caused by a parasite that invades one red blood cell after another. Little is known about this infection process because it happens so quickly, potentially explai...

[Comment] Meningococcal carriage: the dilemma of 4CMenB vaccine

The prevalence of acute bacterial meningitis and septicaemia due to Haemophilus influenzae b (Hib), Streptococcus pneumoniae, and Neisseria meningitidis has greatly decreased in Europe and North Ameri...

[Articles] Effect of a quadrivalent meningococcal ACWY glycoconjugate or a serogroup B meningococcal vaccine on meningococcal carriage: an observer-blind, phase 3 randomised clinical trial

Although we detected no significant difference between groups at 1 month after vaccine course, MenACWY-CRM and 4CMenB vaccines reduced meningococcal carriage rates during 12 months after vaccination a...

Merck Statement regarding Role of PNEUMOVAX 23 in Updated ACIP Recommendations for Pneumococcal Vaccination in Adults

Recommendations call for a two vaccine regimen utilising a dose of the pneumococcal conjugate vaccine followed by a dose of Merck’s PNEUMOVAX 23, at an interval to be determined by the ACIP

US FDA approves first needle-free flu vaccine delivery system

For the first time ever, the US FDA has approved a needle-free injection system to deliver the seasonal flu vaccine.

Events [1 Associated Events listed on BioPortfolio]

Cancer Vaccines 2014

Cancer Vaccines 2014 | Quantify Strategies to Enhance Cancer Vaccine Research and Development

Companies [94 Associated Companies listed on BioPortfolio]

PharmaJet, Inc.

PharmaJet, Inc. is a privately held company located in Denver, Colorado; San Francisco, California and Baltimore, Maryland. It develops, manufactures and markets vaccine and drug delivery products bas...

Igenica Biotherapeutics, Inc.

Igenica Biotherapeutics is focused on the discovery and development of antibodies and antibody-drug conjugates (ADCs) for the treatment of cancer. Igenica is the only biotherapeut...

Redbiotec

Redbiotec is a privately held Swiss biopharmaceutical company founded in 2006 and based in Zurich-Schlieren. The company uses its proprietary rePAX® co-expression tec...

Vaccine & Gene Therapy Institute of Florida

THERAVECTYS

THERAVECTYS is a French biotechnology company engaged in the development of a new generation of vaccines based on the lentiviral vector technology, a breakthrough technology origi...

Biosceptre

Biosceptre has identified a pan-cancer target, present in many cancer types, and importantly not found in healthy tissue. Early research and initial evidence suggest that drugs di...

TNG Pharmaceuticals, Inc.

TNG Pharmaceuticals is a Louisville, KY based animal pharmaceutical company focused on the development of its patented vaccine for cattle, FlyVax™, to aid in control of the h...

SynAffix

SynAffix is a protein engineering company located in Oss (the Netherlands), focused on the development of next-generation Antibody-Drug Conjugates (ADCs) for targeted cancer and other diseases. SynA...

PaxVax Inc.

PaxVax is a privately held specialty vaccine company founded in 2007. PaxVax is focused on traveler vaccines with an emerging pipeline in biodefense coupled with a social mission...

ImmusanT Inc.

ImmusanT is a privately-held biotechnology company focused on restoring tolerance to gluten in celiac disease by harnessing new discoveries in immunology that aim to improve diagn...

Clinical Trials [2012 Associated Clinical Trials listed on BioPortfolio]

Safety of and Immune Response to Two HIV Vaccines: SAAVI DNA-C2 Boosted With SAAVIMVA-C, in HIV-Negative Adults

The purpose of this study is to evaluate the safety of and immune response to an experimental DNA HIV vaccine followed by boosting with an experimental modified vaccinia HIV vaccine (MVA)...

iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma/VEGAS

PLEASE NOTE - THIS STUDY IS CURRENTLY ONLY RECRUITING PARTICIPANTS WITH OSTEOSARCOMA. The purpose of this study is to find the largest safe dose of GD2-T cells (also called iC9-GD2-CAR-V...

Efficacy and Safety of a Pentavalent Rotavirus Vaccine (BRV-PV) Against Severe Rotavirus Gastroenteritis in Niger

The study is a double-blinded, randomized, placebo-controlled, trial with two groups of infants receiving vaccine or placebo to assess the efficacy and safety of BRV-PV. Three doses of BRV...

Evaluate a New Shigella Sonnei Vaccine Administered Either by Intradermal, Intranasal or Intramuscular Route in Healthy Adults

This Phase 1 clinical trial is aimed to evaluate the safety and immunogenicity of 3 doses of a candidate vaccine against Shigella sonnei (1790GAHB vaccine) when administered at different d...

The Safety and Immunogenicity of a Potential HIV Vaccine

The potential HIV vaccine has two components: a protein immunogen based on the coat protein of HIV; and an adjuvant which enhances the vaccinee's response to the immunogen. The immunogen i...

ICI-VPH: Impact of HPV Immunisation Schedules Against HPV

This randomised clinical trial aims to determine whether an immunization schedule comprising two doses of Gardasil administered six months apart is non-inferior to a schedule comprising th...

Safe Administration of Flu Vaccine to Egg Allergic Children

Historically, providing influenza vaccination of egg allergic children and young adults (EAC) with a history of anaphylaxis to egg, or other severe symptoms of an allergic reaction to egg...

Evaluating the Safety and Immune Response to Two Doses of a Dengue Virus Vaccine Administered 12 Months Apart

Dengue viruses can cause dengue fever and other more severe forms of disease. This study will evaluate the safety and immune response to two doses of a dengue virus vaccine given 12 months...

Study of the Safety and Immunogenicity of a Novel H5N1 Influenza Vaccine in Healthy Adults Age 18-49

The purpose of this study is to test an investigational vaccine known as "VAX161C." An "investigational" vaccine is one that is not licensed for commercial use in the by the United States...

A Phase II Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive Tract

Head and neck squamous cell carcinoma (HNSCC) is a lethal solid malignancy with 5 year survival estimates of approximately 50%, and is associated with a high rate of systemic immune impair...

Medical and Biotech [MESH] Definitions

A combined vaccine used to prevent infection with diphtheria and tetanus toxoid. This is used in place of DTP vaccine (DIPHTHERIA-TETANUS-PERTUSSIS VACCINE) when PERTUSSIS VACCINE is contraindicated.

A live vaccine containing attenuated poliovirus, types I, II, and III, grown in monkey kidney cell tissue culture, used for routine immunization of children against polio. This vaccine induces long-lasting intestinal and humoral immunity. Killed vaccine induces only humoral immunity. Oral poliovirus vaccine should not be administered to immunocompromised individuals or their household contacts. (Dorland, 28th ed)

A bacterial vaccine for the prevention of brucellosis in man and animal. Brucella abortus vaccine is used for the immunization of cattle, sheep, and goats.

A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had mumps or been immunized with live mumps vaccine. Children are usually immunized with measles-mumps-rubella combination vaccine.

A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had measles or been immunized with live measles vaccine and have no serum antibodies against measles. Children are usually immunized with measles-mumps-rubella combination vaccine. (From Dorland, 28th ed)

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