Meningococcal Conjugates Vaccine - Biotech, Pharma and Life Science Channel

08:51 EDT 5th July 2015 | BioPortfolio

PubMed Articles [2006 Associated PubMed Articles listed on BioPortfolio]

Fabrication of chitosan microspheres using vanillin/TPP dual crosslinkers for protein antigens encapsulation.

Microspheres were prepared from water soluble chitosan using dual vanillin/TPP crosslinkers. Placebo (C1), Bovine serum albumin (BSA) (C2), monovalent tetanus toxoid (TT) (C3) and divalent tetanus (TT...

Chitosan-isoniazid conjugates: Synthesis, evaluation of tuberculostatic activity, biodegradability and toxicity.

Novel water-soluble chitosan-isoniazid conjugates were synthesized by two methods: (1) the carbodiimide method using isoniazid (INH) and N-(2-carboxyethyl)chitosan (CEC), and (2) the reaction between ...

Improvement of emulsifying properties of oat protein isolate-dextran conjugates by glycation.

In order to improve the emulsifying properties of oat protein, oat protein isolate (OPI)-dextran (Dex) conjugates were prepared by glycation reaction. Emulsifying properties of emulsions stabilized by...

Impact of immunosuppressive therapy on hepatitis B vaccination in inflammatory bowel diseases.

The vaccination rate against hepatitis B virus (HBV) is low in inflammatory bowel disease (IBD) patients. The Consensus from the European Crohn's and Colitis Organisation on opportunistic infections r...

Sexual Orientation Identity Disparities in Awareness and Initiation of the Human Papillomavirus Vaccine Among U.S. Women and Girls: A National Survey.

Lesbians and bisexual women are at risk for human papillomavirus (HPV) infection from female and male sexual partners.

Antibodies: At The Nexus of Antigens and Cancer Vaccines.

This review describes the development of monoclonal antibodies and the inception of their use in cancer therapy, their impact on defining cancer biomarkers, and their structural utility in new cancer ...

From Immunity and Vaccines to Mammalian Regeneration.

Our current understanding of major histocompatibility complex (MHC)-mediated antigen presentation in self and nonself immune recognition was derived from immunological studies of autoimmunity and viru...

Developing a Successful HIV Vaccine.

Human immunodeficiency virus (HIV) genome integration indicates that persistent sterilizing immunity will be needed for a successful vaccine candidate. This suggests a need for broad antibodies target...

Increasing Complexity of Vaccine Development.

Vaccines already developed have been enormously successful. However, the development of future vaccines requires solution of a number of immunologic problems, including pathogen variability, short eff...

Quercetin-POM (pivaloxymethyl) conjugates: Modulatory activity for P-glycoprotein-based multidrug resistance.

We previously demonstrated that the bioactivity of quercetin could be improved through conjugation with a hydrolysable pivaloxymethyl (POM) group.

News Articles [2467 Associated News Articles listed on BioPortfolio]

Immigrant children given adult dose of hepatitis A vaccine

About 250 immigrant children were given an adult dose of a hepatitis A vaccine at a Texas detention facility where they were being held with their mothers, according to U.S. Immigration and Customs En...

US vaccine researcher is jailed for fraud

A vaccine researcher in the United States who admitted to fabricating and falsifying HIV vaccine research results has been sentenced to 57 months in prison and ordered to repay $7.2m (£4.6m; €6.5m)...

Week in Review: June 29?July 3

Sex differences in processing pain; clue in flu vaccine–narcolepsy link found; early antibiotic use affects the gut microbiome; lizard sex determined by genes, then temperature

Ex Iowa State Scientist Gets Prison for Faking HIV Research

(Yahoo! News) – A former Iowa State University scientist who altered blood samples to make it appear he had achieved a breakthrough toward a potential vaccine against HIV was sentenced Wednesday...

Scientists find new clues to GSK's Pandemrix's narcolepsy issue

Pandemrix was given to high-risk groups at the height of the pandemic, including children and those with asthma, diabetes and heart disease; in all around 30 million people across Europe received the ...

J&J vaccine completely prevented HIV in half of monkeys in trial

CHICAGO (Reuters) - An experimental Johnson & Johnson vaccine completely prevented HIV infection in half of monkeys that got the shot and then were exposed to high doses of an aggressive virus, result...

California ends vaccine exemptions on grounds of belief--will other states follow?

After a bitter battle, California has ended vaccine exemptions on the basis of religion or personal belief. Under the new law, signed by Governor Jerry Brown on 30 June, unvaccinated children in the.....

Vaccine for AIDS in ten years: Bill Gates

Biospectrum Mr Bill Gates spends millions of dollars on AIDS drug development and research [Read more]

Researcher Who Faked HIV Vaccine Gets Prison Term, Millions in Fines

Read more about Researcher Who Faked HIV Vaccine Gets Prison Term, Millions in Fines

Hepatitis B Vaccine Ineffective in Most Patients With RA

Many patients with rheumatoid arthritis (RA) do not achieve adequate levels of protection against hepatitis B when vaccinated with HBVAXPRO-10. Medscape Medical News

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Companies [100 Associated Companies listed on BioPortfolio]

EY Laboratories inc

Manufacturer of biochemical reagents serving the needs of biochemical research in glycobiology, immunology, and microbiology. Manufacturer of rapid, simple, and stable diagnostic test kits for visual ...

Aduro BioTech, Inc.

Aduro BioTech is a clinical-stage immunotherapy company with a platform technology for therapeutic and prophylactic vaccines for cancer and infectious diseases. The platform of at...

ADC Therapeutics Sarl

ADC Therapeutics (ADCT) is a Swiss-based oncology drug development company that specializes in the development of proprietary Antibody Drug Conjugates (ADCs) targeting major cance...

The Vaccine & Gene Therapy Institute of Florida (VGTI Florida)

Targovax

Targovax was started in October 2010 to develop TG01, a vaccine targeting pancreatic cancer. TG01 is based on research from The Radium Hospital and Norsk Hydro in the end of the 9...

Genocea Biosciences

Genocea Biosciences was founded in 2006 to commercialize key breakthroughs in vaccine discovery and development. The Company’s proprietary T cell-directed antigen disc...

The Vaccine & Gene Therapy Institute of Florida

ImmusanT Inc.

ImmusanT is a privately-held biotechnology company focused on restoring tolerance to gluten in celiac disease by harnessing new discoveries in immunology that aim to improve diagn...

Affinivax Inc.

Affinivax is advancing a next generation conjugate vaccine technology platform to enable the development of vaccines that provide the highest level of protection against challengi...

Mucosis B.V.

Mucosis B.V. (Mucosis) is a clinical-stage biotechnology company using a proprietary technology platform to develop next-generation needle-free human vaccines for infectious disea...

Clinical Trials [2250 Associated Clinical Trials listed on BioPortfolio]

Glembatumumab Vedotin in Treating Patients With Recurrent or Refractory Osteosarcoma

This phase II trial studies how well glembatumumab vedotin works in treating patients with osteosarcoma that has come back (recurrent) or does not respond to treatment (refractory). Antibo...

DC Vaccine Therapy Combined With Cytokine-Induced Killer Cell in Treating

The purpose of this study is to show if vaccination with autologous dendritic cells pulsed with tumor lysate in combination with Cytokine-Induced Killer Cell (CIK) can induce a measurable ...

A Study to Evaluate the Safety and Immunogenicity of a Candidate Ebola Vaccine in Adults

The purpose of this study is to assess the safety and immunogenicity of the investigational ChAd3-EBO-Z vaccine administered to approximately 3 000 adults in Africa as a single IM dose Con...

Analysis of Bone Marrow and Blood B Cell Immune Responses to Influenza Vaccination

The primary objective investigate the longevity of humoral immunity to influenza virus in humans. Our overarching hypothesis is that an understanding of how long-term humoral immunity to i...

Evaluation of a New Ebola Vaccine Using a Short-interval Prime-boost Vaccination

This is a clinical trial in which healthy volunteers will be administered two experimental Ebola vaccines: ChAd3-EBO Z and MVA-EBO Z. Two groups of volunteers will be vaccinated with both ...

A Pilot Study to Assess the Immunogenicity of Candidate PSA Peptides for a Prostate Cancer Vaccine

To measure antigen-specific interferon-secretion by enzyme-linked immunospot (ELISPOT) assay, which measures antigen-specific interferon-secretion.

Vaccine Enriched, Autologous, Activated T-Cells Directed to Tumor in Patients With Relapsed/Refractory Melanoma

The researchers will investigate if modified T-cells from a patients own system can be utilized to find and destroy metastatic melanoma tumor and thus improve patient outcomes.

Baby Vaccine Study (Sched3)

This multicentre, parallel group, block randomised clinical trial aims to investigate the post booster antibody response in UK infants given a reduced priming schedule of meningococcal ser...

A Single-center, Open Trials to Evaluate the Safety of Freeze-dried Group ACYW135 Meningococcal Conjugate Vaccine

Safety Evaluation of freeze-dried Group ACYW135 Meningococcal conjugate vaccine in healthy people above 2-months-old

Study to Evaluate the Safety and Immunogenicity of 'IL-YANG Flu Vaccine Quadrivalent Inj' in Healthy Korean Adults

This study evaluates the safety, tolerability and immunogenicity of IL-YANG quadrivalent vaccine versus IL-YANG trivalent vaccine after a single intramuscular administration in healthy Kor...

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Medical and Biotech [MESH] Definitions

A combined vaccine used to prevent infection with diphtheria and tetanus toxoid. This is used in place of DTP vaccine (DIPHTHERIA-TETANUS-PERTUSSIS VACCINE) when PERTUSSIS VACCINE is contraindicated.

A live vaccine containing attenuated poliovirus, types I, II, and III, grown in monkey kidney cell tissue culture, used for routine immunization of children against polio. This vaccine induces long-lasting intestinal and humoral immunity. Killed vaccine induces only humoral immunity. Oral poliovirus vaccine should not be administered to immunocompromised individuals or their household contacts. (Dorland, 28th ed)

A bacterial vaccine for the prevention of brucellosis in man and animal. Brucella abortus vaccine is used for the immunization of cattle, sheep, and goats.

A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had mumps or been immunized with live mumps vaccine. Children are usually immunized with measles-mumps-rubella combination vaccine.

A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had measles or been immunized with live measles vaccine and have no serum antibodies against measles. Children are usually immunized with measles-mumps-rubella combination vaccine. (From Dorland, 28th ed)


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