Menopause - Biotech, Pharma and Life Science Channel
The menopause is a natural event for all women; the ovaries no longer produce estrogen and progesterone. This can be due to natural aging (usual age of onset is 51 years), or through chemotherapy and surgery on the ovaries. The changing balance of the hormones in a women's body is thought to result in the symptoms on the menopause; estrogen and progesterone fall while levels of FSH and LH rise.
Perimenopause is the stage from the beginning of menopausal symptoms to the postmenopause.
Postmenopause is the time following the last period, and is usually defined as more than 12 months with no periods in someone with intact ovaries, or immediately following surgery if the ovaries have been removed.
As the roles of the reproductive hormones are better defined, the menopause (the decline in levels of these hormones) is becoming a more significant indicator of risk of various diseases.
Source; Adapted from Menopause Matters (.co.uk)
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PubMed Articles
Assessment of Alveolar Bone Mineral Density as a Predictor of Lumbar Fracture Probability.
INTRODUCTION: Osteoporosis and tooth loss have been linked with advancing age, but no clear relationship between these conditions has been proven. Several studies of bone mineral density measurements...
PURPOSE: The purpose of this study was to study the relationships among menopausal symptoms, sexual function, depression, and quality of life in women with breast cancer undergoing chemotherapy. METHO...
Abstract Background: Although low back pain and obesity are major health issues for women, our understanding of the relationship between these conditions is limited. This study aimed to investigate th...
Postmenopausal breast cancer, androgens, and aromatase inhibitors.
Recent data can help to better define the long debated relationship between androgens and breast cancer (BC) after menopause. We reviewed the available literature data on: the origin of androgens afte...
Evidence on the association between dietary flavonoids and lignans and breast cancer (BC) risk is inconclusive, with the possible exception of isoflavones in Asian countries. Therefore, we investigate...
Hypertension is a major challenge for public health. Appropriate antihypertensive treatment seem to provide a better life with lower morbidity and mortality rates. Another pathologic condition, osteop...
The aim of this study was to evaluate the relationship between vitamin E status and osteoporosis in early postmenopausal women. Anthropometric data, osteoporosis risk factors, vitamin E serum levels,...
The influence of blood glucose on neutrophil function in individuals without diabetes.
We assessed the association of neutrophil function with glycated hemoglobin (HbA1c) levels in a Japanese general population. Participants were 809 males and females who were over 20 years old living i...
Management of cancer treatment-induced bone loss.
The survival prospects for many patients with cancer are steadily improving. As a result, survivorship issues are of increasing importance as attempts are made to minimize the long-term adverse effect...
Female hormones are very important in regulating bone homeostasis; the drop of estrogen levels occurring at menopause is linked to a dramatic prevalence of bone resorption on formation. Only a small n...
News Articles
New Survey Results from 3,000 Postmenopausal Women Living with Vulvar and Vaginal Atrophy
FLORHAM PARK, N.J., May 16, 2013 /PRNewswire/ -- A new survey of more than 3,000 postmenopausal women reveals that women living with vulvar and vaginal atrophy (VVA) are either unaware of what ca...
Sturdier Immune System May Explain Why Women Live Longer
redOrbit Staff & Wire Reports - Your Universe Online Women's immune systems age more slowly than men's, which may contribute to their longer average lifespans, according to new research published...
Healthy skin requires pairing the right products for a person's skin condition. Find out how SkinCeuticals makes it easy. Sacramento, CA (PRWEB) May 16, 2013 SkinCeuticals is a premium skincare b...
Risk Of Cardiovascular Disease Not Increased By Hysterectomy
Having a hysterectomy with or without ovary removal in mid-life does not increase a woman's risk of cardiovascular disease compared to women who reach natural menopause, contrary to many previously re...
Understanding the impact asthma has on women and why it affects them more than men. Fairfax, VA (PRWEB) May 15, 2013 Asthma is a disease that affects people's lungs. Asthma is a disorder that cau...
New Evidence Shows Hysterectomy Does Not Increase Risk Of Heart Disease
Brett Smith for redOrbit.com - Your Universe Online While previous research has shown a connection between the medical removal of a woman’s uterus and heart problems, a new study in the Journal of...
Hysterectomy Does Not Raise Heart Risk
Contrary to some previous research, a new study from the US finds women's risk of cardiovascular disease does not go up after having a hysterectomy in mid-life, with or without ovary removal. The ri...
Hysterectomy does not increase risk of cardiovascular disease, study finds
Having a hysterectomy with or without ovary removal in mid-life does not increase a woman's risk of cardiovascular disease compared to women who reach natural menopause, contrary to many previously re...
Hysterectomy does not increase risk of cardiovascular disease
Having a hysterectomy with or without ovary removal in mid-life does not increase a woman's risk of cardiovascular disease compared to women who reach natural menopause, contrary to many previously re...
Clarisonic Technology for All Skincare Concerns – The Latest Article by Skincare-News.com
The latest article by Skincare-News discusses how Clarisonic skin cleansing devices can make a world of difference in anyone's skin, no matter their age, skin type or skin condition. Sacramento, C...
Events
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Companies
TherapeuticsMDÂ is a specialty pharmaceutical company focused on creating safe and effective therapies exclusively for women. The Companyâs branded OTC and pharmaceutical p...
BioSante Pharmaceuticals, Inc. and ANI Pharmaceuticals, Inc.
BioSanteâs corporate strategy is to develop high value medically-needed pharmaceutical products and to implement strategic alternatives with respect to its products and its c...
BioSante Pharmaceuticals, Inc.
BioSante is a specialty pharmaceutical company focused on developing products for female sexual health and oncology. BioSanteâs lead products include LibiGel® (transdermal...
Antares Pharma, Inc. and Population Council
Antares Pharma focuses on self-injection delivery technologies and topical gel-based pharmaceutical products. The Companyâs subcutaneous injection technology platforms includ...
Founded in 2003, BodyLogicMD physician-owned practices make up the nationâs largest and fastest growing network of the most highly trained physicians specializing in natural...
Antares Pharma focuses on self-injection delivery technologies and topical gel-based pharmaceutical products. The Company's subcutaneous and intramuscular injection technology pla...
Clinical Trials
Impact of Hot Flashes on Sleep and Mood Disturbance
We plan to enroll 60 healthy, non-pregnant premenopausal women age 18-45 who do not have hot flashes (in order to have 30 women complete all study procedures) in a trial investigating the...
Proliferation of Endometrial Stromal Cells in Adenomyosis
Adenomyosis refers to the presence of endometrial glands and stroma that is haphazardly deep within the myometrium. However, the etiology and pathologic mechanism responsible for adenomyos...
The primary purpose of this study is to determine the effects of a full dose (300 mg at hs) of oral micronized progesterone (OMP) on vasomotor symptoms [VMS] (hot flushes/night sweats), on...
Non-Comparative Study To Evaluate Changes In FMD After Quinapril Therapy In Hypertensive Women
ACE inhibitors are thought to modify the endothelium in a number of ways. Quinapril is an effective and well-tolerated ACE-I for the treatment of patients with hypertension and congestive...
Black Cohosh as Alternative Therapy for Treating Menopause-Related Anxiety
This study will determine the effectiveness of the herb black cohosh for treating menopause-related anxiety symptoms in women. Study hypotheses: 1) Black cohosh will have a superior anti-...
RATIONALE: Hormone replacement therapy may be effective in relieving symptoms of menopause, such as hot flashes, night sweats, and vaginal dryness, without causing a recurrence of breast c...
Using Soy Estrogens to Prevent Bone Loss and Other Menopausal Symptoms
The purpose of this study is to determine if soy-derived phytoestrogens (naturally occurring compounds similar to estrogen) can prevent bone loss and other menopausal symptoms in women who...
Goserelin in Preventing Ovarian Failure in Women Receiving Chemotherapy for Breast Cancer
RATIONALE: Goserelin blocks hormone production in the ovaries. It is not yet known whether ovarian suppression using goserelin will prevent ovarian failure (early menopause) in women recei...
HIV-1 Vaccine Test in Uninfected Adult Volunteers
This study will test the safety of an experimental vaccine against HIV and examine whether it induces an immune response to HIV. A vaccine is a substance given to try to create resistance...
Hormone Replacement Therapy and Anti-HIV Drugs in HIV-Infected, Postmenopausal Women
The purpose of this study is to find out if the anti-HIV drugs nelfinavir (NFV), lopinavir/ritonavir (LPV/r), and efavirenz (EFV) change the amount of estrogen in the blood when taken alon...
Videos
Understanding Menopause (Menopause #1)
Every woman goes through it, yet many don't discuss this natural time of life. Learn more about menopause in this video.
Medical and Biotech [MESH] Definitions
Perimenopause
The transitional period before and after MENOPAUSE. Perimenopausal symptoms are associated with irregular MENSTRUAL CYCLE and widely fluctuated hormone levels. They may appear 6 years before menopause and subside 2 to 5 years after menopause.
Osteoporosis, Postmenopausal
Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency.
Reproductive History
An important aggregate factor in epidemiological studies of women's health. The concept usually includes the number and timing of pregnancies and their outcomes, the incidence of breast feeding, and may include age of menarche and menopause, regularity of menstruation, fertility, gynecological or obstetric problems, or contraceptive usage.
Premenopause
The period before MENOPAUSE. In premenopausal women, the climacteric transition from full sexual maturity to cessation of ovarian cycle takes place between the age of late thirty and early fifty.
Postmenopause
The physiological period following the MENOPAUSE, the permanent cessation of the menstrual life.
