Metabolic Nephropathies - Biotech, Pharma and Life Science Channel
PubMed Articles
We examined the relationships between bone mineral density (BMD) and metabolic syndrome in 6,659 men and 7,826 women from South Korean. After adjusting for age, body mass index (BMI), tobacco and alco...
Adapting glycolysis to cancer cell proliferation: the MAPK pathway focuses on PFKFB3.
Besides the necessary changes in the expression of cell cycle-related proteins, cancer cells undergo a profound series of metabolic adaptations focused to satisfy their excessive demand for biomass. A...
Inflammatory conditions can profoundly alter human neutrophils, a leukocyte subset generally viewed as terminally differentiated and catabolic. In cystic fibrosis (CF) patients, neutrophils recruited...
Astilbin, a natural flavonoid, has been shown to have a selective immunosuppressive activity on activated T lymphocytes. In our previous study, 3'-O-methylastilbin was identified as an active metaboli...
Dose effect of cardiorespiratory exercise on metabolic syndrome in postmenopausal women.
As an ancillary report to a large National Institutes of Health (NIH)-funded trial, we examined the effects of 6 months of exercise training at 50%, 100%, and 150% of the NIH Consensus Recommendations...
Previous studies demonstrated that low-level postnatal and early life exposure to the environmental contaminant, trichloroethylene (TCE), in the drinking water of MRL+/+ mice altered glutathione redox...
Neovascularization in diabetes and its complications. Unraveling the angiogenic paradox.
Diabetes mellitus (DM) is a chronic metabolic disease characterized by the presence of hyperglycemia, which can lead to many complications over time. These complications, such as nephropathy, retinopa...
Fish oil (FO) and tetradecylthioacetic acid (TTA) - a synthetic modified fatty acid have beneficial effects in regulating lipid metabolism. In order to dissect the mechanisms underlying the molecular...
A non-structured model was used to study the dynamics of gibberellic acid production in a stirred tank bioreactor. Experimental data were obtained from submerged batch cultures of Gibberella fujikuroi...
Adiponectin and metabolic syndrome: pathway on the relationship.
News Articles
Woman Experiences Astonishing Recovery from Fibromyalgia
SHELBY TOWNSHIP, Mich., June 19, 2013 /PRNewswire/ -- Heather Shinsky experienced the full range of trauma that is typical to the two to four percent of the population suffering from fibromyalgia...
Fat Tissues In Sheep Affected By Prenatal Exposure To BPA
New research suggests that fetal exposure to the common environmental chemical bisphenol A, or BPA, causes increased inflammation in fat tissues after birth, which can lead to obesity and metabolic sy...
Heart Failure And Hypertension Meds May Help Decrease Obesity
A type of drug normally used to treat heart failure and high blood pressure helped prevent weight gain and other complications related to a high-fat diet in an animal study. The results were presented...
Variants In The SIM1 Gene Associated With Severe Obesity
Although body weight is largely determined by lifestyle factors, increasingly research is revealing that genetics also play an important role in determining an individual's susceptibility to obesity....
Exercise Plus Diet Key to Kids' Weight Loss (CME/CE)
(MedPage Today) -- Diet and exercise together were more effective at dropping weight and improving metabolic profiles in overweight children compared with diet-only interventions, researchers found.
[MedImmune] and [NGM] to develop new therapies for diabetes and obesity
[AstraZeneca PLC]’s biologics division [MedImmune LLC] has teamed up with cardio and metabolic disease drug company [NGM Biopharmaceuticals Inc.] to discover and develop new diabetes and obesity the...
Thule Therapeutics S.A., an R&D Company of the Sigma-Tau Group, and Corequest Sagl announce extremely valuable findings on the use of L-Carnitine in peritoneal dialysis soluti...
Skipping breakfast associated with higher risk of obesity and diabetes, U of M study finds
Eating breakfast — even among people whose dietary habits are not all that nutritional — is associated with a lower rate of obesity, high blood pressure, type 2 diabetes, and metabolic syndrome (a...
An Obese Teen: More Than Meets the Eye
Not all obese teens develop metabolic complications, but many do. Test your knowledge with this case challenge. Medscape Pediatrics
Study Says Two Drug Types May Combat Obesity And Treat Metabolic Syndrome
redOrbit Staff & Wire Reports - Your Universe Online Medications typically prescribed to treat heart failure and high blood pressure could potentially be used to battle obesity and the combinatio...
Events
Diabetes: Secondary Complications, Regulation and Innovation Conference
SMi is very proud to present our 11th conference focusing on Diabetes and metabolic disorders taking place on 1st and 2nd Oct 2013, London.
Companies
Verdezyne is an industrial biotechnology company using proven and proprietary metabolic pathway engineering tools to create unique yeast strains for cost-effective production of b...
AstraZeneca and Bristol-Myers Squibb
Dedicated to addressing the global burden of diabetes by advancing individualized patient care, AstraZeneca and Bristol-Myers Squibb are working in collaboration to research, deve...
Estibio was founded in 2012 as a spin out of BioGasol ApS, to commercialise its first and second generation bioethanol fermentation technology and services. Estibio’s VHTP (Very High Tem...
Aegerion Pharmaceuticals, Inc.
Aegerion Pharmaceuticals is a biopharmaceutical company dedicated to the development and commercialization of innovative, life-altering therapies for patients with debilitating often fatal, rare dis...
Astellas Pharma Inc., located in Tokyo, Japan, is a pharmaceutical company dedicated to improving the health of people around the world through the provision of innovative and reliable pharmaceuticals...
KineMed, Inc. ("KineMed" or the "Company") is a drug discovery and development company employing its proprietary translational medicine technology (AquaTag™ and KineMarkerâÂ...
Health Discovery Corporation is a molecular diagnostics company that uses advanced mathematical techniques to analyze large amounts of data to uncover patterns that might otherwis...
Circadian Technologies Limited
Circadian Technologies Limited is an emerging leader in the field of angiogenesis-based treatments for cancer. Focusing on a class of drug targets called Vascular Endothelial Growth Factors (VEGFs),...
Nimbus Discovery, a biotechnology company, harnesses cutting-edge computational technologies to uncover breakthroughs in small molecule pharmacology. Nimbus focuses on medically i...
TheAmerican Association of Clinical Endocrinologists (AACE)
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
Clinical Trials
Phase I study to evaluate the excretion of radioactivity, the metabolic profile, pharmacokinetics, safety and tolerability following a single oral administration of [14C] Prucalopride Succ...
Malnutrition, including muscle wasting commonly occurs in children with cystic fibrosis (CF), negatively influencing their quality of life and survival. At the time of a diagnosis of CF, s...
Evaluation of Pulse Fibre Supplementation on Obesity and the Metabolic Syndrome
The recent dramatic increase in obesity has been linked to a reduction of dietary fibre intake. We hypothesized that supplementing the diet of overweight and obesity adults with pulse fibr...
Background: The interactive effects of resistance training and dietary protein on hormonal responses in overweight or obese adults are not clear and remain controversial. Investigators tes...
Mediators of Abnormal Reproductive Function in Obesity (MARO)
The study is seeking to understand how being overweight and obese makes women less fertile. The studies the investigators have done so far indicate that there is a hormone or other substan...
Glutamine Enriched Total Parenteral Feeding and Proline Metabolism in Severely Burned Patients
Proline is a non-essential amino acid that helps with collagen formation. Collagen is one of the main ingredients of skin, bone, tendons, and connective tissue. It is thought that proline...
Islet Transplantation in Type 1 Diabetic Patients
Our hypothesis is that a successful clinical islet transplant program can be established at the University of Wisconsin using a steroid -free, sirolimus- and low dose tacrolimus - based im...
Low cobalamin (vitamin B12) levels are frequent in the elderly. Most often they reflect a mild metabolic abnormality without clinical symptoms (subclinical cobalamin deficiency). It is unc...
The Survey About Resting Metabolic Rate and Its Related Factors in Terminal Patients
According to data from the Taiwanese government, cancer mortality has been the leading cause of death in Taiwan since 1982. The trend is increasing day by day. As the people are aging in T...
Changes in Adiposity, Metabolic Measures From Atypicals to Aripiprazole
This proposal aims to use well-validated methodologies such as dual energy x-ray absorptiometry (DEXA), frequently sampled oral glucose tolerance tests (fsOGTTs), and hyperinsulinemic eugl...
Videos
Acute Renal Failure Explained Clearly! 1 of 3
Understand Acute Renal Failure (also called acute kidney injury) with this clear explanation from Dr. Roger Seheult. Video 1 of 3. MedCram: Medical Topics Ex...
Medical and Biotech [MESH] Definitions
Iron-regulatory Proteins
Proteins that regulate cellular and organismal iron homeostasis. They play an important biological role by maintaining iron levels that are adequate for metabolic need, but below the toxicity threshold.
Estrogenic Steroids, Alkylated
Estrogenic STEROIDS with aliphatic hydrocarbon chain substitution on C17 or other position. 17-alpha-ALKYLATION renders the molecule more stable, resistant to metabolic degradation, and improves oral efficacy. Examples of synthetic alkyl estrogens include ETHINYL ESTRADIOL and MESTRANOL. Substitutions at other sites generates antiestrogenic and cytotoxic properties.
Steroid Metabolism, Inborn Errors
Errors in metabolic processing of STEROIDS resulting from inborn genetic mutations that are inherited or acquired in utero.
Desulfovibrio Gigas
A species of gram-negative, anaerobic, spiral-shaped bacteria originally isolated from a saltwater pond in France. It contains a well-characterized metabolic pathway that enables it to survive transient contacts with OXYGEN.
Ileus
A condition caused by the lack of intestinal PERISTALSIS or INTESTINAL MOTILITY without any mechanical obstruction. This interference of the flow of INTESTINAL CONTENTS often leads to INTESTINAL OBSTRUCTION. Ileus may be classified into postoperative, inflammatory, metabolic, neurogenic, and drug-induced.
