Mntrier's disease - Biotech, Pharma and Life Science Channel
PubMed Articles
EIF4G1 Ala502Val and Arg1205His variants in Chinese patients with Parkinson disease.
Growing evidences show that genetic abnormalities play an important role in the etiopathogenesis of Parkinson disease (PD). At least 18 genetic loci and 13 disease-related genes for parkinsonism have...
The effect of estrogen in a man with Parkinson's disease and a review of its therapeutic potential.
Estrogen has been implicated in controlling the pathogenesis and symptoms of Parkinson's disease (PD) in women. Here, we report a 53-year-old male with PD who underwent estrogen therapy with estradiol...
Despite its increasing popularity, little is known about the health effects of waterpipe smoking (WPS), particularly on the cardiovascular system. To investigate the role of WPS as a risk factor for v...
In patients with stable ischemic heart disease (SIHD), myocardial revascularization should be performed to either improve survival or improve symptoms and functional status among patients who are not...
Vascular factors in the pathogenesis of Alzheimer's disease.
According to the amyloid hypothesis of Alzheimer's disease (AD), the amyloid β (Aβ) peptide, as the primary neurotoxic species, plays a key role in the pathogenesis of the disease. However, many lin...
PURPOSE: To determine whether there is a significant association between human immunodeficiency virus (HIV)-related retinal microangiopathy and systemic cytomegalovirus (CMV) disease in HIV-infected p...
Insulin resistance, lipodystrophy and cardiometabolic syndrome in HIV/AIDS.
HIV associated insulin resistance, lipodistrophy and cardiometabolic syndrome have been extensively studied and continue to be the scope of much research. There is compelling evidence that both the HI...
Assessing rheumatoid arthritis disease activity with ultrasound.
In practice, composite indices are used for rheumatoid arthritis (RA) disease activity evaluation. Despite valid and widely used, not rarely composite indices miss accuracy. Ultrasound (US) is more pr...
Serum levels of IgG and IgG4 in Hashimoto thyroiditis.
Although IgG4-related disease is characterized by extensive infiltration of IgG4-positive plasma cells and lymphocytes of various organs, the details of this systemic disease are still unclear. We scr...
The influence of early diagnosis of endometrioid endometrial cancer on disease stage and survival.
OBJECTIVE: To evaluate whether the presence or duration of uterine bleeding is associated with disease stage, and survival of patients with endometrioid endometrial carcinoma (EEC). METHODS: The recor...
News Articles
Blood Velocity Predicts Brain Disease (CME/CE)
(MedPage Today) -- The velocity of blood through the aortic arch is an independent predictor of cerebral microvascular disease, researchers reported.
Cytori banks on its real-time stem cell treatment for heart disease
In the near future, chronic heart disease patients could find themselves in an outpatient clinic, getting a new treatment that is not much more complicated than donating platelets at the Red Cross. (F...
New animal model gives insights into mechanisms of Parkinson's disease pathogenesis
In Parkinson's disease, the protein "alpha-synuclein" aggregates and accumulates within neurons. Specific areas of the brain become progressively affected as the disease develops and advances. The mec...
High Cadmium Levels May Raise Risk for Dying From Liver Disease: Study
FRIDAY, May 24 (HealthDay News) -- People with high levels of cadmium in their urine are much more likely to die of liver disease than those with lower levels, a new study finds. A high level of cadm...
Scientists have developed a novel experimental model that reproduces for the first time this pattern of alpha-synuclein brain spreading and provides important clues on the mechanisms underlying this p...
Galapagos and AbbVie extend collaboration to include Crohn’s disease
Galapagos NV and AbbVie have agreed to extend their GLPG0634 clinical development collaboration to include Crohn’s disease. Galapagos will fund and complete a Phase 2 programme in the disease design...
A Review Of Upcoming Catalysts For Kidney Disease Biotech Players In 2013
ByTech Guru:With a potential U.S. market for Chronic Kidney Disease (CKD) and End Stage Renal Disease (ESRD) patients of almost $1bb, based on 5mm CKD patients above age 65, of whom ~5...
Alzheimer's disease, the soft target of the euthanasia debate
(Medical Xpress)—The way Alzheimer's disease is portrayed by advocacy groups and the media is having undue influence on the euthanasia debate, according to a Deakin University nursing ethics profess...
Research: Anti-cancer drug tested as possible treatment for Alzheimer's disease proved ineffective
An anti-cancer drug about to be tested in a clinical trial by a biomedical company in Ohio as a possible treatment for Alzheimer's disease has failed to work with the same type of brain plaques that p...
FDA clears Omeros' IND for OMS824 in Huntington's disease
The US Food and Drug Administration (FDA) has cleared Omeros' investigational new drug application (IND) for OMS824 in Huntington's disease.
Events
Welcome to AgriGenomics World Congress 2013.
14th INTERNATIONAL CONFERENCE ON ALZHEIMER'S DRUG DISCOVERY
The annual Alzheimer's Drug Discovery Foundation (ADDF) conference brings together academic and industry scientists intent on accelerating the development of innovative treatments for Alzheimer’s di...
Companies
The Multiple Myeloma Research Foundation
Multiple myeloma is an incurable blood cancer. The five-year relative survival rate for multiple myeloma is approximately 34 percent, one of the lowest of all cancers. In 2009, ap...
KineMed, Inc. ("KineMed" or the "Company") is a drug discovery and development company employing its proprietary translational medicine technology (AquaTag™ and KineMarkerâÂ...
Diabetes Care Club, a Simplex brand, has grown to become the third largest mail-order supplier of diabetic testing supplies for seniors. The company provides home delivery...
From its establishment in 1977, simply as a Distributor of diagnostic products, IDS has become a globally-recognised innovator and marketeer in the IVD industry.The Company is particularly well-known...
National Disease Research Interchange (NDRI)
Alvine Pharmaceuticals, Inc. is a private, clinical-stage, specialty biopharmaceutical company located in San Carlos, CA, focused on the development of biologics targeting autoimm...
Reverse Medical Corporation is a privately-held medical device company focused on expanding the endovascular management of acute stroke and neurovascular disease. The technology p...
PatientsLikeMe is a patient network that improves lives and a real-time research platform that advances medicine. Through the network, patients connect with others who have the sa...
Nimbus Discovery, a biotechnology company, harnesses cutting-edge computational technologies to uncover breakthroughs in small molecule pharmacology. Nimbus focuses on medically i...
VGTI Florida is the Florida-funded expansion of Oregon Health & Science University's highly successful Vaccine and Gene Therapy Institute. Research at the facility will focus on v...
Clinical Trials
A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)
The main purpose of the study is to evaluate the efficacy and safety of the study drug known as prasugrel for the reduction of Vaso-Occlusive Crisis events in pediatric participants with s...
Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders
The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of,...
An Efficacy and Safety Study of Galantamine for the Treatment of Patients With Alzheimer's Disease
The purpose of this study is to evaluate the efficacy and safety of two fixed doses (16mg/day and 24mg/day) of galantamine (a drug for treating dementia) versus placebo for the treatment o...
A Study in Patients With Diabetic Kidney Disease
The purpose of this study is to determine if LY2382770 is safe and effective at protecting kidney function in patients with kidney disease due to diabetes.
Parkinson's Disease Registry of the Muhammad Ali Parkinson Center
The purpose of the Parkinson’s disease Registry is to develop a national and international database of persons with Parkinson’s disease (PD). The Registry will be used to facilitate t...
D-Serine Adjuvant Treatment for Parkinson's Disease
The proposed experiment will evaluate the effects of the NMDA receptor full agonist D-serine (~2g/day) on persistent symptoms of Parkinson's Disease and on antiparkinsonian drugs-induced d...
The Fabry Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Fabry disease, irrespective of trea...
Study Of PHarmacogenetics in Ethnically Diverse Populations (SOPHIE Study)
Collect DNA from well-characterized healthy volunteers. DNA will be used to identify and determine allele frequencies of genetic variants in membrane transporters and other genes relevant...
Selenium Supplementation in Chronic Obstructive Pulmonary Disease (COPD) Patients
Does an oral selenium supplement increase blood levels of antioxidants in patients with established, smoking-related lung disease? Members of our study group recently discovered that elev...
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease
This study was designed to evaluate the symptomatic effects of Coenzyme Q10 nanodispersed solution in middle-stage Parkinson's disease (PD) patients (Hoehn&Yahr II to III). The treatment p...
Videos
Medical and Biotech [MESH] Definitions
Casuistry
A method of ETHICAL ANALYSIS that emphasizes practical problem solving through examining individual cases that are considered to be representative; sometimes used to denote specious argument or rationalization. Differentiate from casuistics, which is the recording and study of cases and disease.
Incidental Findings
Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.
Wasting Disease, Chronic
A transmissible spongiform encephalopathy (prion disease) of DEER and elk characterized by chronic weight loss leading to death. It is thought to spread by direct contact between animals or through environmental contamination with the prion protein (PRIONS).
Ulmus
A plant genus of the family ULMACEAE that is susceptible to Dutch elm disease which is caused by the ASCOMYCOTA fungus, Ophiostoma.
Virulence Factors
Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)
