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Moderate-to-Severe Plaque Psoriasis - Biotech, Pharma and Life Science Channel

11:16 EDT 19th August 2017 | BioPortfolio

Psoriasis is a chronic, immune disease that affects the skin. It occurs when the immune system sends out faulty signals that speed up the growth cycle of skin cells. Psoriasis affects up to 1.8 million people in the UK,ix approximately 20 percent of whom have moderate-to-severe plaque psoriasis.Psoriasis can occur on any part of the body and is associated with other serious health conditions, such as diabetes and heart disease. The most common form of psoriasis, plaque psoriasis, appears as raised, red patches covered with a silvery white buildup of dead skin cells.

News Articles [133 Associated News Articles listed on BioPortfolio]

Plaque Psoriasis Market Insights, Epidemiology and Market Forecast 2025 [Report Updated: 31072017] Prices from USD $5750

DelveInsight's Plaque Psoriasis Market Insights, Epidemiology and Market Forecast 2025 report provides an overview of the disease and in depth research related to Plaque Psoriasis for the 7MM Unit...

Forward Pharma A/S FWP Financial and Strategic SWOT Analysis Review [Report Updated: 07082017] Prices from USD $300

SummaryForward Pharma AS Forward Pharma is a biopharmaceutical company that develops immunomodulatory compound for the treatment of inflammatory and neurological indications. The company provides dime...

Plaque Psoriasis Global API Manufacturers, Marketed and Phase III Drugs Landscape, 2017 [Report Updated: 01072017] Prices from USD $2000

DelveInsight's, Plaque Psoriasis Global API Manufacturers, Marketed and Phase III Drugs Landscape, 2017 report provides comprehensive insights about marketed and Phase III products for the Plaque Pso...

Severe Psoriasis Epidemiology Insights to 2025 [Report Updated: 31072017] Prices from USD $2950

DelveInsight's Severe Psoriasis Epidemiology Forecast, 2025 provides an overview of the epidemiology trends of Severe Psoriasis in seven major markets US, France, Germany, Italy, Spain, UK and Japan. ...

Medical Marijuana, Inc. Subsidiary HempMeds® Brasil To Hold Its Second Doctor Symposium on Medical Cannabis in Sao Paulo, Brazil

SAN DIEGO, Aug. 14, 2017 /PRNewswire/ -- Medical Marijuana, Inc. (OTC:MJNA), the first publicly traded cannabis company in the United States, today announced that its subsidiary HempMeds® Brasil...

Moderate Psoriasis Pipeline Insight, 2017 [Report Updated: 31072017] Prices from USD $1250

DelveInsight's, Moderate PsoriasisPipeline Insights, 2017, report provides comprehensive insights of the ongoing therapeutic research and development across Moderate Psoriasis. The report provides a c...

Global Dermatology Drugs Market to 2023 - Growth Driven by Increased Uptake of Interleukin Receptor Inhibitors for Psoriasis and Atopic Dermatitis

LONDON, Aug. 10, 2017 /PRNewswire/ -- SummaryDermatology is a highly diverse therapy area that deals with diseases of the skin, hair and nails. Over 3,000 types of dermatological conditions are t...

Cipher Pharmaceuticals Inc CPH Pharmaceuticals Healthcare Deals and Alliances Profile [Report Updated: 26072017] Prices from USD $250

SummaryCipher Pharmaceuticals Inc Cipher is a pharmaceutical company that develops skin care solutions. The company offers products such as actikerall, a topical solution indicated for the treatment o...

Plaque Psoriasis Pipeline Insight, 2017 [Report Updated: 31072017] Prices from USD $1250

DelveInsight's, Plaque PsoriasisPipeline Insights, 2017, report provides comprehensive insights of the ongoing therapeutic research and development across Plaque Psoriasis. The report provides a compl...

Moderate Psoriasis Market Insights, Epidemiology and Market Forecast 2025 [Report Updated: 31072017] Prices from USD $5750

DelveInsight's Moderate Psoriasis Market Insights, Epidemiology and Market Forecast 2025 report provides an overview of the disease and in depth research related to Moderate Psoriasis for the 7MM ...

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Companies [22 Associated Companies listed on BioPortfolio]

Can-Fite BioPharma Ltd.

Can-Fite BioPharma Ltd. (NYSE MKT: CANF) (TASE: CFBI) is an advanced clinical stage drug development Company with a platform technology that is designed to address multi-billion d...

Arrien Pharmaceuticals

Arrien Pharmaceuticals is a targeted therapeutics drug discovery and development company. Arrien applies its proprietary fragment-based FIELDS drug discovery technology to targ...

Tiziana Life Sciences plc

Tiziana Life Sciences plc is a UK biotechnology company that focuses on the discovery and development of novel molecules that treat human disease in oncology and immunology. The C...

Santalis Pharmaceuticals, Inc.

Santalis Pharmaceuticals, Inc. is a wholly-owned subsidiary of TFS Corporation, Ltd. (ASX: TFC). Santalis, and its sister company, ViroXis, were acquired by TFS in July 2015 and a...

Ziarco Pharma Ltd.

Ziarco is a clinical-stage biotechnology company developing innovative therapeutics targeting dermatological and inflammatory diseases. ZPL-389, the Company’s lead compound, ...

Akaal Pharma Pty Ltd.

Akaal Pharma Pty Ltd (Akaal Pharma) is a clinical-stage drug discovery and development company focused on the development of novel small molecule drugs for the treatment of inflam...

Provectus Biopharmaceuticals, Inc.

Provectus Biopharmaceuticals specializes in developing oncology and dermatology therapies. Its novel oncology drug PV-10 is designed to selectively target and destroy cancer cells...

Shape Pharmaceuticals, Inc.

Shape Pharmaceuticals, Inc. is developing SHP-141, a novel, topical, “soft-drug” HDAC inhibitor for the treatment of patients with cutaneous T cell lymphoma (CTCL) and p...

Helmedix Pty Ltd

Helmedix is developing new therapies for autoimmune diseases. The company has identified peptides derived from helminthic worms that have immune-modulating properties. These peptides are being explo...

HealOr

Founded in 2002, HealOr is a privately owned, clinical-stage specialty biopharmaceutical company developing a first-in-class pipeline of topical therapeutics to treat a variety of...

Clinical Trials [549 Associated Clinical Trials listed on BioPortfolio]

An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects

An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects

A Study Examining the Medication Apremilast as Treatment for Chronic Itch

Chronic Itch is a debilitating condition affecting many people. Currently, there are no FDA-approved treatments. Apremilast is an FDA-approved oral medication used to successfully treat th...

A Study to Evaluate the Effectiveness and Patient-Reported Outcome of Adalimumab in Patients With Moderate to Severe Plaque Psoriasis in China

The objective of this non-interventional, observational study is to assess the effectiveness and patient reported outcome of adalimumab in patients with moderate to severe psoriasis in rea...

Multiple Dose Study With Incremental Dosing to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral Doses of LEO 32731 in Healthy Male Japanese Subjects.

This trial will investigate the safety, tolerability and pharmacokinetic (PK) data of LEO 32731 (and major human metabolite LEO 40815) in healthy male Japanese subjects. The primary object...

This is a Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Adult Patients With Chronic Plaque Psoriasis.

This is a study to assess the long-term safety, tolerability, and efficacy of bimekizumab.

Study of Icotinib Hydrochloride Cream in Patients With Mild to Moderate Psoriasis

This is a phase II study to evaluate the efficacy and safety of Icotinib Hydrochloride Cream in patients with mild to moderate psoriasis.

Impact of AbbVie Care Patient Support Program on Clinical, Health Economic and Patient Reported Outcomes, in Crohn's Disease, Ulcerative Colitis, Rheumatoid Arthritis, Psoriatic Arthritis, Psoriasis and Ankylosing Spondylitis, in the Portuguese National H

This study aims to evaluate the impact of AbbVie Care 2.0 on adalimumab's compliance, patient reported outcomes and utilization of health resources over 12 months.

A Safety Study of Ustekinumab in the Treatment of Pediatric Participants Aged 12 Years and Older With Moderate to Severe Plaque Psoriasis

The purpose of this study is to monitor the long-term safety of ustekinumab in pediatric participants (aged greater than or equal to 12 years to less than 18 years inclusive) with moderate...

A Study Comparing the Safety and Efficacy of Risankizumab to Methotrexate in Subjects With Moderate to Severe Plaque Psoriasis

The purpose of this study is to compare the safety and efficacy of risankizumab to methotrexate in participants with moderate to severe plaque psoriasis.

MAP Study: Methotrexate and Adalimumab in Psoriasis

Assess the efficacy and safety of ADA compared to ADA/MTX in patient with Psoriasis. Compare Anti-ADA antibody formation and serum ADA levels in patients on ADA compared with those on comb...

PubMed Articles [346 Associated PubMed Articles listed on BioPortfolio]

Molecular and cellular discoveries in inflammatory dermatoses.

It was no earlier than 1986 that T helper (Th)1 and Th2 cells were described for the first time, opening the field of lymphocyte diversity and the investigation of the physiopathology of inflammatory ...

HIV Infection Increases the Risk of Incident Psoriasis: A Nationwide Population-Based Cohort Study in Taiwan.

HIV can cause an imbalance of T lymphocytes, which may contribute to the onset of psoriasis. However, the association of HIV with incident psoriasis has not been extensively studied.

Immune Modulation by Curcumin: The Role of Interleukin-10.

Cytokines are small secreted proteins released by different types of cells with specific effects on cellular signaling and communication via binding to their receptors on the cell surface. IL-10 is kn...

Association of variably expressed KIR3dl1 alleles with psoriatic disease.

The purpose of this study is to examine the genetic interaction of variably expressed killer cell immunoglobulin-like receptor (KIR) 3DL1 alleles with their cognate ligand, human leukocyte antigen (HL...

Progress in genetic research on psoriatic arthritis.

Psoriatic arthritis is a form of inflammatory arthritis found among patients with psoriasis, which can lead to pain, swelling or stiffness in one or more joints and even movement disorders. Epidemiolo...

Patients with psoriasis have different preferences for topical therapy, highlighting the importance of individualized treatment approaches: Randomized Phase IIIb PSO-INSIGHTFUL study.

Poor adherence to topical therapy in psoriasis remains an issue; it is associated with poor clinical outcomes, reduced quality of life, and increased costs. Treatment-related factors leading to poor a...

Rate of serious infection in patients who are prescribed systemic biologic or nonbiologic agents for psoriasis: A large, single center, retrospective, observational cohort study.

Systemic biologic and nonbiologic agents used to treat psoriasis may or may not contribute to serious infection (SI) risk. Safety data, particularly for biologic agents, and associated risk for SI, ar...

Purpura Annularis Telangiectodes of Majocchi Associated With the Initiation and Rechallenge of Apremilast for Psoriasis Vulgaris.

Mania Induced by Narrowband Ultraviolet B Phototherapy Treatment: A Case Report and Review of the Literature.

Phototherapy has been used for decades in the treatment of many common dermatologic conditions, such as psoriasis, atopic dermatitis, cutaneous T cell lymphoma, vitiligo, and scleroderma, among others...

PDTCM: A systems pharmacology platform of traditional Chinese medicine for psoriasis.

Psoriasis is a refractory skin disorder, and usually requires a lifetime control. Traditional Chinese medicine (TCM) is effective and safe for this disease. However, the cellular and molecular mechani...

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Medical and Biotech [MESH] Definitions

A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

A topical anti-inflammatory glucocorticoid used in DERMATOSES, skin allergies, PSORIASIS, etc.

A glucocorticoid used topically in the treatment of DERMATITIS; ECZEMA; or PSORIASIS. It may cause skin irritation.

An anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.

A humanized monoclonal antibody that binds to IL-12 and IL-23 and is used as a DERMATOLOGIC AGENT in the treatment of patients with plaque PSORIASIS who have not responded to other therapies.

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