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PubMed Articles
SIRT1 mediates the protective function of Nkx2.5 during stress in cardiomyocytes.
Nkx2.5 plays protective roles in cardiac homeostasis and survival in the postnatal hearts. However, the underlying molecular mechanisms that mediate the protective functions of Nkx2.5 remain unknown....
Inositol pyrophosphates: between signalling and metabolism.
The present review will explore the insights gained into inositol pyrophosphates in the 20 years since their discovery in 1993. These molecules are defined by the presence of the characteristic 'high...
Response to 'Human fist evolution: a critique'.
Human fist evolution: a critique.
Assembling the 20 Gb white spruce (Picea glauca) genome from whole-genome shotgun sequencing data.
White spruce (Picea glauca) is a dominant conifer of the boreal forests of North America, and providing genomics resources for this commercially valuable tree will help improve forest management and c...
The san francisco declaration on research assessment.
Discovery of new potent inhibitors for carbonic anhydrase IX by structure-based virtual screening.
Through structure-based virtual screening, some dozen of benzene sulfonamides with novel scaffolds are identified as potent inhibitors against carbonic anhydrase (CA) IX with IC50 values ranging from...
Transcriptional profiling can elucidate adaptive/toxicity pathways participating in achieving homeostasis or leading to pathogenesis in marine biota exposed to chemical substances. With the aim of ana...
News Articles
Sanofi, Curie-Cancer enter ovarian cancer collaboration
Sanofi and the Curie Institute, through its Curie-Cancer partnership, have announced the establishment of a three-year research collaboration to identify new therapeutic targets for the development of...
San Diego, CA (PRWEB) June 19, 2013 Adding to their already extensive supply of high quality pipettes, Pipette.com is now stocked with Simportâs Dropette® and Heathrow Scientific disposa...
Breakthrough research of essential molecule reveals important targets in diabetes and obesity
Insulin is the most potent physiological anabolic agent for tissue-building and energy storage, promoting the storage and synthesis of lipids, protein and carbohydrates, and inhibiting their breakdown...
Impact Analytical Opens New State-of-the-Art Laboratory Facility
Impact Analytical, a full-service, contract analytical testing laboratory that serves the pharmaceutical, plastics, consumer products, medical device, packaging, automotive...
LARKSPUR, Calif., June 19, 2013 /PRNewswire/ -- BioCision, a leader in advanced products to improve sample standardization and handling in many areas of medical and scientific research, announced...
MO BIO Laboratories, Inc. launches the first kit for protein extraction from soil
CARLSBAD, Calif., June 19, 2013 /PRNewswire/ -- MO BIO Laboratories, Inc., the leader in soil, plant, stool and other challenging microbial nucleic acid purification, announces the launch of the NoviP...
G-Sphere Standard for Molecular Norovirus Assays The G-Sphere range of Molecular Standards from Phthisis Diagnostics has expanded to include both parasites and viruses. Synthetic controls for No...
Calysta Energy to Harness Microbes for Bioplastics Maker NatureWorks
Eight months after its public debut, Menlo Park, CA-based Calysta Energy has announced its first partnership deal. Calysta, a synthetic biology company, will attempt to engineer a new microbe that can...
Invivoscribe FLT3 Testing Patents Strengthened by Supreme Court Ruling
SAN DIEGO, CA -- (Marketwired) -- 06/19/13 -- In Association of Molecular Pathology v. Myriad, the U.S. Supreme Court struck down BRCA1 and BRCA2 gene patent claims. It is important for the diagnosti...
Certain Types Of Graft-Versus-Host Disease May Increase Risk Of Death
Joseph Pidala, M.D., M.S., assistant member of the Blood and Bone Marrow Transplant and Immunology programs at Moffitt Cancer Center, and colleagues from the Chronic Graft-Versus-Host Disease Consorti...
Events
Biotechnology for the Non Biotechnologist - Comprehensive 3 day course
Biotechnology for the Non Biotechnologist - Comprehensive 3 day course
Cancer Vaccines will provide attendees with a complete view of the cancer immunotherapy field. Focusing on the discovery of new vaccines, developments in target identification
Welcome to Molecular Medicine Congress and exhibition.
3rd Annual Next Generation Sequencing Asia Congress 2013
Over 200 NGS, Genomics, Metagenomics, Epigenetics, Bioinformatics & Data Management senior scientists from Asia
Ribosomes Napa Valley Conference 2013
Protein synthesis by the ribosome plays a central role in connecting genotypes to phenotypes in biology.
Companies
Allen Institute for Brain Science
Launched in 2003, the Seattle-based Allen Institute for Brain Science is an independent, 501(c)(3) nonprofit medical research organization dedicated to advancing brain research. Started with $100 mill...
Fraunhofer Center for Molecular Biotechnology
Fraunhofer-Gesellschaft(FhG) is the leading organization for applied research in Europe with 66 research institutes and 22,000 employees. U.S. subsidiary Fraunhofer USA is headqua...
Daylight Solutions develops molecular detection, imaging and high-power illumination systems for use in industrial process controls, scientific research, medical diagnostics, envi...
Based in Brisbane, California, XDx is a molecular diagnostics company focused on the discovery, development and commercialization of noninvasive gene expression-based tests for th...
Sequenta, Inc. is a privately held company developing and commercializing molecular diagnostic assays based on a proprietary sequencing approach to the profiling of T and B cell r...
Biodesix is a personalized medicine company focused on the development of diagnostic products that inform treatment decisions and improve patient care. In 2009, Biodesix launched VeriStrat®, a serum...
Ambry Genetics is a CAP-accredited, CLIA-certified commercial clinical laboratory headquartered in Aliso Viejo, California. Since the company's inception in 2000, it has become a leader in provi...
Auxogyn – Advancing women’s reproductive health through novel scientific and clinical knowledge of early human developmental biology auxology (from Greek αὔξω, auxō,...
Foundation Medicine is dedicated to the development of comprehensive tests that will help physicians personalize cancer treatment for their patients. Foundation Medicineâs la...
Health Discovery Corporation is a molecular diagnostics company that uses advanced mathematical techniques to analyze large amounts of data to uncover patterns that might otherwis...
Clinical Trials
Fat Biology, Sleep Disorders, and Cardiovascular Disease
Endothelial dysfunction, or abnormal functioning of the lining of blood vessels, appears to be a key process in the development of cardiovascular disease. Endothelial dysfunction appears t...
Nephrotic Syndrome Study Network
Minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and Membranous nephropathy (MN), generate an enormous individual and societal financial burden, accounting for appr...
Medical scientists want to find better ways to treat neuroblastoma and to find ways to prevent the tumor from growing back. To do this, they need more information about the characteristics...
The purpose of this study is to obtain an estimate of catheter survival in the setting of upper extremity deep vein thrombosis (UEDVT) in patients treated with dalteparin and warfarin....
This is a prospective study of surgically resected samples and lymph nodes of lung cancer patients. For histopathologically positive lymph nodes from a complete resection, the investigator...
Extension Neoadjuvant Taxotere: Study of the Effects of Taxotere in Patients With Breast Cancer
We, the investigators at Baylor Breast Care Cancer, are doing this study to learn how well Taxotere makes tumors become smaller. We are also doing this study to find out how well Taxotere...
Treatment Protocol for Relapsed Acute Promyelocytic Leukemia (APL) With Arsenic
Summary Acute promyelocytic leukemia is defined by a characteristic morphology (AML FAB M3/M3v), by the specific translocation t(15;17) and its molecular correlates (PML/RARa and RARa/PML...
In an attempt to simplify the diagnosis of ectopic pregnancy, the researchers will investigate the presence of specific molecular markers of ectopic pregnancy. The quantification of these...
Blood clots in the leg veins, known as deep vein thrombosis, are important because they may travel to the lung (known as pulmonary embolism) and cause death. Blood clots are treated with...
PROphylaxis for ThromboEmbolism in Critical Care Trial (PROTECT)
The purpose of this study is to evaluate the effect of Low Molecular Weight Heparin (LMWH) (dalteparin) versus Unfractionated Heparin (UFH) on the primary outcome of proximal leg Deep Vein...
Videos
Molecular Biology
Paul Andersen explains the major procedures in molecular biology. He starts with a brief description of Taq polymerase extracted from the hot pools of Yellow...
Medical and Biotech [MESH] Definitions
Biomimetics
An interdisciplinary field in materials science, ENGINEERING, and BIOLOGY, studying the use of biological principles for synthesis or fabrication of BIOMIMETIC MATERIALS.
Andrology
A scientific or medical discipline concerning the study of male reproductive biology, diseases of the male genital organs, and male infertility. Major areas of interest include ENDOCRINOLOGY; SPERMATOGENESIS; semen analysis; FERTILIZATION; CONTRACEPTION; and CRYOPRESERVATION.
Dynamins
A family of high molecular weight GTP phosphohydrolases that play a direct role in vesicle transport. They associate with microtubule bundles (MICROTUBULES) and are believed to produce mechanical force via a process linked to GTP hydrolysis. This enzyme was formerly listed as EC 3.6.1.50.
Biomedical Research
Research that involves the application of the natural sciences, especially biology and physiology, to medicine. (from American Heritage Dictionary, 4th ed)
Leukocyte Rolling
Movement of tethered, spherical LEUKOCYTES along the endothelial surface of the microvasculature. The tethering and rolling involves interaction with SELECTINS and other adhesion molecules in both the ENDOTHELIUM and leukocyte. The rolling leukocyte then becomes activated by CHEMOKINES, flattens out, and firmly adheres to the endothelial surface in preparation for transmigration through the interendothelial cell junction. (From Abbas, Cellular and Molecular Immunology, 3rd ed)