Motor Neuron Disorders - Biotech, Pharma and Life Science Channel
PubMed Articles
The interstitial cells of Cajal (ICCs) act as pacemaker cells that are involved in gastrointestinal (GI) motility disorders, although the pathogenesis of these disorders is still unclear. The GI tract...
PURPOSES: The purpose of this study was to evaluate the feasibility and safety of esophageal functional magnetic resonance imaging (fMRI) for the diagnosis of achalasia. METHODS: Eleven patients with...
High rate of disease-related copy number variations in childhood onset schizophrenia.
Copy number variants (CNVs) are risk factors in neurodevelopmental disorders, including autism, epilepsy, intellectual disability (ID) and schizophrenia. Childhood onset schizophrenia (COS), defined a...
An MRI atlas of the mouse basal ganglia.
The basal ganglia are a group of subpallial nuclei that play an important role in motor, emotional, and cognitive functions. Morphological changes and disrupted afferent/efferent connections in the b...
Sirtuin deacetylases in neurodegenerative diseases of aging.
Sirtuin enzymes are a family of highly conserved protein deacetylases that depend on nicotinamide adenine dinucleotide (NAD+) for their activity. There are seven sirtuins in mammals and these proteins...
Motor neuron disease: Two new ALS susceptibility loci identified in Han Chinese.
Movement disorders: Novel MRI measure for diagnosis of progressive supranuclear palsy.
BACKGROUND: The Grin1 (glutamate receptor, ionotropic, NMDA1) gene expresses a subunit of N-methyl-D-aspartate (NMDA) receptors that is considered to play an important role in excitatory neurotransmis...
BACKGROUND: Stress-related mental disorders (SRMD), which correspond to the diagnostic code F43 in the International Classification of Diseases, version 10, rank among the leading causes of sickness a...
Significant sequelae after bacterial meningitis in Niger: a cohort study.
BACKGROUND: Beside high mortality, acute bacterial meningitis may lead to a high frequency of neuropsychological sequelae. The Sahelian countries belonging to the meningitis belt experience approximat...
News Articles
Recognition, assessment and treatment of social anxiety disorder: summary of NICE guidance
Social anxiety disorder is one of the most persistent and common of the anxiety disorders, with lifetime prevalence rates in Europe of 6.7% (range 3.9-13.7%).1 It often coexists with depression,......
Signs of motor disorders can appear years before disease manifestation
It is known that signs of neurological disorders such as Alzheimer's and Huntington's disease can appear years before the disease becomes manifest; these signs take the form of subtle changes in the b...
Kennedy Krieger Institute and Partek Incorporated Awarded $1.8M NIH Grant
Research partnership aimed at developing computational tools to analyze genomic data from patients with autism spectrum disorder and mental health disorders Partek...
New Prescription Medical Food May Be Beneficial in Dietary Management of IBS-D
EnteraGam™ (Serum-derived bovine immunoglobulin/protein isolate, SBI) Available Soon Entera Health, Inc. announces today three presentations were given at Digestive D...
Natus Files 2013 First Quarter Form 10-Q
- Cures Lack of Compliance Notice from Nasdaq Natus Medical Incorporated (Nasdaq:BABY) today announced that it has filed its Quarterly Report on Form 10-Q for the three months...
Corgenix Announces Diagnostic Development Agreement with Lilly
-- Companies to focus on potential companion diagnostic opportunity -- Corgenix Medical Corporation (OTCBB: CONX), a worldwide developer and marketer of diagnostic test...
Omeros to Present at Two Upcoming Conferences
SEATTLE, May 22, 2013 /PRNewswire/ -- Omeros Corporation (NASDAQ: OMER), a biopharmaceutical company committed to discovering, developing and commercializing products focused on inflammation, ble...
Remuda Ranch Sponsor of 6th Annual HEAL Conference
Remuda Ranch, a comprehensive treatment center specializing in eating and co-occurring disorders for women and girls, is a sponsor of the 6th Annual Healthy Eating and Living (HEAL) Conference in Ashe...
Seva Call Revs Its Engines to Launch in Motor City
Detroit, Michigan (PRWEB) May 22, 2013 Seva Call (Save-A-Call) has launched in Detroit, Michigan. The free service filters through local businesses and connects consumers to the right available pro...
Our observations substantiate the concept that ClC-2 is involved in brain ion and water homoeostasis. Autosomal-recessive CLCN2 mutations cause a leukoencephalopathy that belongs to an emerging group...
Events
None
Companies
Acorda Therapeutics, Inc. was established in March 1995 to develop therapeutic products for spinal cord injury ("SCI") and other central nervous system disorders. Acorda is focusing its initial develo...
ALung Technologies, Inc. is commercializing artificial lung devices for the treatment of acute and chronic respiratory disorders. The company's Hemolung System, designed to replace or supplement the u...
Physician Therapeutics is a division of Targeted Medical Pharma, Inc., a specialty pharmaceutical company that develops and sells prescription medical foods to physi...
Reverse Medical Corporation is a privately-held medical device company focused on expanding the endovascular management of acute stroke and neurovascular disease. The technology p...
Founded in 1990, U.S. Physical Therapy, Inc. (NASDAQ:USPH) operates 369 clinics in 43 states. The Company's clinics provide preventative and post-operative care for a variety of o...
Onconova, based in Newtown, PA and Lawrenceville, NJ, discovers and develops novel patent- protected small molecule therapeutic agents for cancer, radiation protection and hematol...
The Heart Rhythm Society is the international leader in science, education and advocacy for cardiac arrhythmia professionals and patients, and the primary information resource on heart rhythm disorder...
TheAmerican Association of Clinical Endocrinologists (AACE)
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
Lineagen (www.lineagen.com) is a provider of diagnostic and healthcare services focused on complex diseases for which individualsâ genetic profiles contribute strongly to...
Good Start Genetics provides the most clinically relevant genetic information to physicians. The Companyâs affordable pre-pregnancy test, which was developed by the Co...
Clinical Trials
Omega-3 Fatty Acids in Autism Spectrum Disorders
This is a 12-week open label trial to evaluate whether omega-3 fatty acids is effective in reducing the severity of autism and its comorbidities.
The overall goal of the proposed project is: (1) to perform a preliminary study to determine optimal galvanic vestibular stimulation (GVS) settings based on performance of one cognitive te...
USG Nerve Blocks for ACL Reconstruction
Anterior cruciate ligament reconstruction is a routine surgical procedure. Traditional femoral/sciatic block combinations effectively reduce postoperative pain, but results in considerable...
Direct Stimulation Of Spinal Nerve Roots To Determine Sensory And Motor Innervation Patterns
The purpose of this study is to collect data while monitoring muscles and nerves during spine surgery. The data being collected and analyzed will be used to learn more about how the body's...
Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders
The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of,...
This is a Phase III, multicenter, open-label study of RI-002 administered as an intravenous infusion of RI-002 (IGIV) every 21 or 28 days in approximately 60 subjects with Primary Immunode...
The purpose of this study is to assess the pain reduction rate after 8 weeks treatment of NORSPAN® from baseline. And secondary purpose are: pain reduction rate after 4 weeks treatment f...
Both pharmacotherapeutic and psychosocial interventions have domenstrated efficacy for PTSD. However, although these interventions can be helpful, many patients remain symptomatic despite...
Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-Year Manometric Follow-Up
Small bowel involvement is still recognized to be associated with great morbidity and mortality in SSc patients, leading particularly to malabsorption and intestinal pseudo-obstruction. In...
Topical treatment of mild to moderate actinic keratosis located on the face and head with Solaraze® is known to be a safe and efficient treatment option. However, it is unclear if an expa...
Videos
Progress on the Road to Curing Motor Neuron Disease - Professor Chris Shaw
The lecture will cover a description of how we diagnose and treat Motor Neuron Disease, why motor neurons degenrate and the genetic basis of disease. It will...
Medical and Biotech [MESH] Definitions
Tribulus
A plant genus of the family ZYGOPHYLLACEAE. Members contain steroidal saponins. Ingestion by grazing animals causes PHOTOSENSITIVITY DISORDERS called geeldikkop (yellow thick head) in South Africa.
Genetic Services
Organized services to provide diagnosis, treatment, and prevention of genetic disorders.
Gordonia Bacterium
A genus of gram-positive BACTERIA in the family Gordoniaceae, isolated from soil and from sputa of patients with chest disorders. It is also used for biotransformation of natural products.
Mastocytosis, Systemic
A group of disorders caused by the abnormal proliferation of MAST CELLS in a variety of extracutaneous tissues including bone marrow, liver, spleen, lymph nodes, and gastrointestinal tract. Systemic mastocytosis is commonly seen in adults. These diseases are categorized on the basis of clinical features, pathologic findings, and prognosis.
Genetic Research
Research into the cause, transmission, amelioration, elimination, or enhancement of inherited disorders and traits.
