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Multiple Chemical Sensitivity Syndrome - Biotech, Pharma and Life Science Channel

22:35 EDT 25th May 2013 | BioPortfolio

PubMed Articles [ 20085 Associated PubMed Articles listed on BioPortfolio]

Tumor lysis syndrome and malignant melanoma.

Tumor lysis syndrome (TLS) is an oncological emergency that results from massive cytolysis of malignant cells with a sudden release of their contents into the systemic circulation. TLS was rarely desc...

Oligonucleotide suppression of bcl-2 in LNCaP cells is compensated by increased androgen sensitivity, p53 and oncogene activity, and suppressed caspase-3.

Antisense oligonucleotides (oligos) have been employed against prostate cancer models in both in vivo and in vitro systems. While most target growth factors or their receptors, other oligos are direct...

8p21.3 deletion suggesting a probable role of TRAIL-R1 and TRAIL-R2 as candidate tumor suppressor genes in the pathogenesis of multiple myeloma.

8p21.3 deletion was recently characterized in B cell lymphoma suggesting that TRAIL-R1 and TRAIL-R2 may be the target of the deletion and act as dosage-dependent tumor suppressor genes. As multiple my...

Clinical implications of CIP2A protein expression in breast cancer.

The aim of this work is to study the expression and regulatory effects of CIP2A protein in breast cancer and the correlation between CIP2A protein expression and the prognosis of breast cancer. The CI...

Identification of serum microRNAs in genome-wide serum microRNA expression profiles as novel noninvasive biomarkers for malignant peripheral nerve sheath tumor diagnosis.

Recent studies found that serum microRNAs (miRNAs) could serve as stable and noninvasive biomarkers for disease diagnosis. We used genome-wide serum miRNA expression analysis to investigate the role o...

A medical oncologist's perspective on communication skills and burnout syndrome with psycho-oncological approach (To die with each patient one more time: the fate of the oncologists).

The increasing incidence of cancer is at the same time one of the leading causes of death all over the world. Many clinical studies show that the psychological disorders are more frequent in cancer pa...

Evidence for predictive role of BRCA1 and bTUBIII in gastric cancer.

Sensitivity of gastric cancer (GC) to conventional cytotoxic therapy may be at least in part attributed to molecular features of the tumor cells. We analyzed all patients with metastatic GC treated in...

In search of the molecular consequences of 8p21 deletion in multiple myeloma: commentary on Gmidéne et al.

Genetic analysis of candidate SNPs for metabolic syndrome in obstructive sleep apnea (OSA).

Obstructive sleep apnea (OSA) is a common disorder characterized by the reduction or complete cessation in airflow resulting from an obstruction of the upper airway. Several studies have observed an i...

Exploring the reduction in myocardial infarctions in the PLATO trial: Which patients benefited on ticagrelor vs. clopidogrel?

Ticagrelor showed significant reductions in myocardial infarctions (MIs) compared to clopidogrel in the Platelet Inhibition and Patient Outcomes (PLATO) trial. However, there was no explanation as to...

News Articles [ 9218 Associated News Articles listed on BioPortfolio]

Natural Foods For Digestive Health Report and Video Published by BetterDigestion.org

New York, NY (PRWEB) May 25, 2013 The latest report from BetterDigestion.org describes how digestive problems, ranging from irritable bowel syndrome (IBS) to bloating, constipation, diarrhea and ot...

Todd Werpy, ADM to Keynote Present at Biobased Chemicals Conf. (Sept. 16-17, 2013 in San Francisco)

Monrovia, CA, May 25, 2013 --(PR.com)-- Todd Werpy, Vice President of ADM, will give a keynote presentation “Toward a New Generation of Renewable Fuels and Chemicals” at the 4th Biobased...

#SciAmBlogs Friday - Kirk vs. Spock, bridge failure, elephant seals, chemical intuition, predatory journals, sleep learning, and more.

- Jag Bhalla - The Cognitive Science of Star Trek   [More]

Ubiquitin-dependent recruitment of the Bloom Syndrome helicase upon replication stress is required to suppress homologous recombination

The RNF8/RNF168/RAP80 ubiquitin signaling pathway acts not only at DNA double strand breaks but also at stalled replication forks, where it mediates BLM helicase ubiquitination and recruitment.

EU approves Xarelto label expansion

Bayer AG (Xetra:BAYN) said the European Commission approved a label expansion for 2.5 mg twice-daily Xarelto rivaroxaban to include the prevention of atherothrombotic events in combination with standa...

J&J Taking The Long View With Its Therapeutic Franchises

The Big Pharma has only recently entered the diabetes drug market, but has plans to make a significant impact on how the disease is treated. During a meeting with analysts, J&J highlighted the dea...

Personal Injury Law Firm Issues New Infographic Detailing a Potential Link Between Stevens Johnson Syndrome and Common Children’s Medicines

d’Oliveira & Associates has posted a new infographic providing information on a potential association between Stevens Johnson Syndrome and medicines such as Children’s Advil, Children’s Motr...

Using a New UV Light Design, TSK Products Can Prevent HAIs Economically

Borrowing proven UV and peroxide disinfection technologies from municipalities who've used it in water treatment for years provides hospitals with the opportunity to spend less to acquire enhanced...

Obesity, Hypertension Prevalent in Growing Number of Children

Excessive weight in young people suggests their risk for metabolic syndrome, hyperlipidemia, sleep disorders, type 2 diabetes, and kidney disease as adults will be high. Medscape Medical News

The Patient Role in Stimulating Chronic Fatigue Syndrome Drug Development

The Food & Drug Administration convened a two-day meeting with CFS patients, advocates, clinicians and researchers in late April. One of the speakers invited by FDA was former Lilly corporate stra...

Events [ 3 Associated Events listed on BioPortfolio]

Annual Congress of the European Society for Translational Medicine & Global Network Conference on Translational Medicine (EUSTM-2013)

The European Society for Translational Medicine (EUSTM) and the Centre de Recherche Public – Santé (CRP-­Santé)

Flow Chemistry Asia

2nd Flow Chemistry Asia Conference of the Flow Chemistry Society aims to unite and represent those who are actively working on this rapidly developing field.

2nd Annual Forum on Global Publication Planning and Clinical Trial Registries

Attend this highly anticipated forum to learn more about how professionals working in publication planning and clinical trial disclosure can coordinate data sharing to ensure transparency.

Companies [ 336 Associated Companies listed on BioPortfolio]

IFI CLAIMS® Patent Services

IFI CLAIMS Patent Services has been dedicated to enriching patent and curating patent information since the 1950s. We specialize in annotating and classifying patent and scientific documentation usi...

Takeda Pharmaceutical Company Limited

1781 Founding Over two centuries ago in 1781, 32-year-old Chobei Takeda I started a business selling traditional Japanese and Chinese medicines in Doshomachi, Osaka, the center of the medicine trade...

TetraLogic Pharmaceuticals

TetraLogic Pharmaceuticals is a privately held biopharmaceutical company that discovers and develops small molecule drugs that modulate programmed cell death pathways to treat deb...

Perosphere Inc.

Perosphere is a specialty pharmaceutical company that identifies and develops new chemical entities and other therapeutics that can be used as “rescue” drugs. For more i...

The Multiple Myeloma Research Foundation

Multiple myeloma is an incurable blood cancer. The five-year relative survival rate for multiple myeloma is approximately 34 percent, one of the lowest of all cancers. In 2009, ap...

Acorda Therapeutics

Acorda Therapeutics, Inc. was established in March 1995 to develop therapeutic products for spinal cord injury ("SCI") and other central nervous system disorders. Acorda is focusing its initial develo...

PhosphonicS Ltd

PhosphonicS is a world leading developer of precious metal recovery processes in the Cleantech sector. The company’s precious metal scavenger products enable the recovery and recycling of pre...

Dow AgroSciences LLC

Dow AgroSciences LLC, based in Indianapolis, Indiana, USA, is a top-tier agricultural company providing innovative agrochemical and biotechnology solutions globally. The compan...

WIL Research Company, Inc.

WIL Research Company, Inc. is a privately held global Contract Research Organization that provides product safety toxicological research, bioanalytical, and formulation services t...

Forest Laboratories, Inc. & Ironwood Pharmaceuticals, Inc.

Ironwood Pharmaceuticals (NASDAQ: IRWD) is an entrepreneurial pharmaceutical company dedicated to the art and science of great drugmaking. Linaclotide, Ironwood's GC-C agon...

Clinical Trials [ 4060 Associated Clinical Trials listed on BioPortfolio]

Phase III Study With Teriflunomide Versus Placebo in Patients With First Clinical Symptom of Multiple Sclerosis

The primary objective is to demonstrate that early intervention with Teriflunomide in patients presenting with their first clinical episode consistent with MS prevents or delays conversio...

Brain Peripheral Benzodiazepine Receptors in Patients With Multiple Sclerosis

This study will use positron emission tomography (PET) to measure a brain protein called peripheral benzodiazepine receptor (PBR) in patients with multiple sclerosis. PBR is created during...

Nephrotic Syndrome Study Network

Minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and Membranous nephropathy (MN), generate an enormous individual and societal financial burden, accounting for appr...

Marinobufagenin as a Target for DIGIBIND in Preeclampsia

Background: - Preeclampsia is a combination of high blood pressure and other potentially life-threatening symptoms. Preeclampsia occurs in up to 10% of pregnancies and is a...

Noninterventional Study Assessing Cognitive Function and Physical Activity in People With Multiple Sclerosis

Study assessing cognitive function and physical activity in people with relapsing remitting multiple sclerosis.

Intravitreal LFG316 in Patients With Age-related Macular Degeneration (AMD)

This study is designed to test the efficacy of twelve successive monthly doses of intravitreal (IVT) LFG316 on the growth of geographic atrophy (GA) lesions. The study will also provide in...

A Multiple Dose Study of MK-5172 in Hepatitis C-Infected Participants (MK-5172-010 AM1)

This study will compare hepatic pharmacokinetics (PK) derived from liver tissue to plasma PK after administration of MK-5172 to participants with chronic hepatitis C virus (HCV) infection....

MAESTRO-OL: Macitentan in Eisenmenger Syndrome To Restore Exercise Capacity (Open-Label)

Long-term study to evaluate if macitentan is safe, tolerable and efficient enough to be used for treatment of Eisenmenger syndrome.

Safety and Pharmacokinetics of Ifetroban in Hepatorenal Syndrome Patients

Cumberland Pharmaceuticals Inc. (CPI) is developing ifetroban for treatment of hepatorenal syndrome (HRS) and proposes to conduct a study in hospitalized adult patients with HRS to assess...

Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion

This study will evaluate whether the drug mifepristone can improve the symptoms of Cushing's syndrome in people with ectopic adrenal corticotrophin hormone (ACTH) secretion. Cushing's synd...

Medical and Biotech [MESH] Definitions

Monascus

A genus in the family Monascaceae, order EUROTIALES. One species, Monascus purpureus, has multiple uses in traditional Chinese medicine (MEDICINE, CHINESE TRADITIONAL).

Hyperuricemia

Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.

Crangonidae

A family of shrimp in the class CRUSTACEA, order DECAPODA, containing a single genus, Crangon, with multiple species.

Oocysts

Zygote-containing cysts of sporozoan protozoa. Further development in an oocyst produces small individual infective organisms called SPOROZOITES. Then, depending on the genus, the entire oocyst is called a sporocyst or the oocyst contains multiple sporocysts encapsulating the sporozoites.

Heterogeneous-nuclear Ribonucleoprotein K

A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties.

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