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Necrotizing Subcutaneous Infection - Biotech, Pharma and Life Science Channel

12:13 EDT 23rd May 2013 | BioPortfolio

PubMed Articles [ 8693 Associated PubMed Articles listed on BioPortfolio]

Treatment for hepatitis C virus-induced portal hypertension in leukemic children.

Children with acute leukemia are at high risk of hepatitis C infection, either by immunosuppression secondary to chemotherapy or by multiple transfusions of blood products during the course of the dis...

Aortic thrombus and multiple embolisms during a Mycoplasma pneumoniae infection.

We report the case of a patient who presented with a thrombus of the aortic arch complicated with splenic, renal and peroneal artery embolisms, associated with transient lupus anticoagulant, during a...

Encapsulated fat necrosis mimicking subcutaneous liposarcoma: radiologic findings on MR, PET-CT, and US imaging.

We present a case of a subcutaneous encapsulated fat necrosis of the upper extremity that mimicked subcutaneous liposarcoma because of heterogeneous signal intensity, its relatively large size, and pr...

Early enteral nutrition after pancreatoduodenectomy: a meta-analysis of randomized controlled trials.

PURPOSE: The aim of our study was to evaluate the safety and effectiveness of early enteral nutrition (EN) for patients after pancreatoduodenectomy (PD). METHODS: We performed a comprehensive search o...

Microbicides for Prevention of HIV Infection: Clinical Efficacy Trials.

Microbicides are an important HIV prevention technology under development, but the clinical testing of candidate products for efficacy faces many design and ethical challenges. Nevertheless, several m...

Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a prospective randomized study.

PURPOSE: Eradication rates following standard triple therapy for Helicobacter pylori infection are declining. Recent studies, conducted in a number of countries, have shown that sequential therapy for...

Differences in sacral neuromodulation device infection rates based on preoperative antibiotic selection.

INTRODUCTION AND HYPOTHESIS: After SNM implantation the most significant complication that can occur is wound infection, which typically requires removal of all components. Such infections have been r...

Mapping HIV clustering: a strategy for identifying populations at high risk of HIV infection in sub-Saharan Africa.

BACKGROUND: The geographical structure of an epidemic is ultimately a consequence of the drivers of the epidemic and the population susceptible to the infection. The 'know your epidemic' concept recog...

Characterization of Contact Structures for the Spread of Infectious Diseases in a Pork Supply Chain in Northern Germany by Dynamic Network Analysis of Yearly and Monthly Networks.

A major risk factor in the spread of diseases between holdings is the transport of live animals. This study analysed the animal movements of the pork supply chain of a producer group in Northern Germa...

Lipoprotein succession in Borrelia burgdorferi: Similar but distinct roles for OspC and VlsE at different stages of mammalian infection.

Borrelia burgdorferi alternates between ticks and mammals, requiring variable gene expression and protein production to adapt to these diverse niches. These adaptations include shifting among the majo...

News Articles [ 4416 Associated News Articles listed on BioPortfolio]

Study identifies specific genetic factors that influence occurrence and severity of sepsis

A study published in the June issue of Anesthesiology represents an important first step in establishing new therapeutic options targeting specific genetic areas that influence the occurrence and seve...

Fast-acting mothers' milk for healthier babies

Human breastmilk responds quickly to protect the child when there is an infection in mothers or babies, according to new international research led by The University of Western Australia.

Inhibikase Therapeutics to present at Industry Conference on Drug-Induced Progressive Multifocal Leukoencephalopathy (PML)

ATLANTA, May 23, 2013 /PRNewswire/ -- Inhibikase Therapeutics, Inc., an emerging leader in infectious disease treatments, announced today that it will present new results on its antiviral program...

Biologix Solutions LLC is Approved to Offer Infection Control Certificate for All Healthcare Professionals

New York, NY, May 23, 2013 --(PR.com)-- Biologix Solutions LLC, a leader in online continuing education for medical, dental, nursing, physical therapy, occupational therapy and body art professionals...

Cynapsus Therapeutics Reports First Quarter 2013 Financial Results and Recent Developments

TORONTO, ONTARIO -- (Marketwired) -- 05/23/13 -- Cynapsus Therapeutics Inc. (TSX VENTURE: CTH), developing the only non-injectable (i.e. sublingual) delivery of the only approved drug (apomorphine)...

Your Feet Are Home To Nearly 200 Types Of Fungi

Researchers have discovered that there are close to 200 different types of fungi species living on our feet - more than any other part of the body. Although fungi also inhabit other areas of the body...

More Evidence Fecal Transplant Clears C. Diff (CME/CE)

ORLANDO (MedPage Today) -- Fecal transplant for Clostridium difficile infection is a safe and effective treatment and can alter patients' fecal microbiota to resemble that of donors over time, studies...

Fecal microbiota tx feasible for recurrent C. difficile in HIV

(HealthDay)—For HIV-infected individuals with recurrent Clostridium difficile infection, fecal microbiota therapy is feasible, according to a letter published in the May 21 issue of the Annals of In...

Infection Site Predicts Death in Septic Shock (CME/CE)

PHILADELPHIA (MedPage Today) -- The anatomic site where an infection originates predicts mortality among patients diagnosed with septic shock, researchers reported at the American Thoracic Society con...

EMA accelerates Gilead HCV drug

Gilead Sciences hopes to launch sofosbuvir for chronic hepatitis C virus (HCV) infection in the first half of 2014 in Europe after the European Medicines Agency ( EMA) accepted the firm's marketing a...

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Companies [ 46 Associated Companies listed on BioPortfolio]

InSite Vision

InSite Vision is an ophthalmic products company currently focused on ocular infection, glaucoma, and retinal disease. The Company specializes in three platform technologies: topical drug delivery (Dur...

Bio-Intervention Specialists

Bio-IS does not replace the environmental services staff. Instead, Bio-IS works with hospital leadership, infection control committees and environmental services to implement a ne...

Kimberly-Clark Health Care

Around the world, medical professionals turn to Kimberly-Clark for a wide portfolio of solutions that improve the health, hygiene and well-being of their patients and staff. As pa...

Great Basin Corporation

Great Basin Corporation is a privately held life sciences company that commercializes breakthrough multiplex chip-based technologies for the molecular, rapid diagnostic testing ma...

Achaogen, Inc.

Achaogen is a clinical-stage biopharmaceutical company focused on the discovery and development of antibiotics for the treatment of serious infections caused by multi-drug resista...

HyGreen, Inc.

HyGreen, Inc. is an innovative technology company whose mission is to improve lives by safeguarding health through technology. Its HyGreen® Hand Hygiene product provides hospit...

DISC Sports & Spine Center

As an official medical services provider of the United States Olympic Committee (USOC) and Red Bull’s US athletes, DISC Sports and Spine Center (DISC) is one of America’...

TREM Rx, Inc.

TREM Rx is a biotechnology company with a proprietary technology platform to create and administer highly effective vaccines that are delivered to the upper layers of skin, rather...

TYRX®, Inc.

TYRX, Inc. commercializes innovative, implantable combination drug+device products focused on infection control, including the AIGISRx® Antibacterial Envelope, designed to redu...

Ariste Medical, Inc.

Ariste Medical, Inc. is a privately held biotechnology company developing novel, first-in-class, drug-eluting devices to reduce infection, restenosis, and thrombosis. Located in t...

Clinical Trials [ 1873 Associated Clinical Trials listed on BioPortfolio]

Immune Response to Hepatitis C Virus

This study will identify and characterize immune factors involved in hepatitis C infection and elimination of the virus. Individual responses to hepatitis C infection vary; some people ar...

A Study to Compare Subcutaneous Versus Intravenous Administration of Herceptin (Trastuzumab) in Women With HER2-Positive Early Breast Cancer

In this open-label multicenter trial patients with operable or locally advanced breast cancer will be randomized to pre-operative treatment with 8 cycles of chemotherapy (docetaxel followe...

Moxifloxacin in Pediatric Subjects With Complicated Intra-abdominal Infection

The primary focus of the study is the evaluation of the safety of treatment with moxifloxacin in a pediatric population 3 months to

A Multiple Dose Study of MK-5172 in Hepatitis C-Infected Participants (MK-5172-010 AM1)

This study will compare hepatic pharmacokinetics (PK) derived from liver tissue to plasma PK after administration of MK-5172 to participants with chronic hepatitis C virus (HCV) infection....

To Compare the Strategies of Universal Antibiotic Prophylaxis Versus Screen-and-treat in Reducing Infective Complications and Re-infection in Women Who Undergo Termination of Pregnancy

Screen-and-treat approach reduces postabortal pelvic inflammatory disease after induced abortion, and at the same time alters women's sexual behavior and prevents further re-infection by s...

A Phase I Study of Intralesional Bacillus Calmette-Guerin (BCG) and Followed by Ipilimumbab Therapy in Patients With Advanced Metastatic Melanoma

This is an open-label, dose-escalation, non-randomized, phase I study in patients with histologically confirmed Stage III or IV melanoma and at least three metastatic cutaneous or subcutan...

NIRS and Doppler to Predict NEC in Risk Neonates

The main objective is to evaluate the interest of cerebro-splanchnic oxygenation ratio (CSOR) for early diagnosis of necrotizing enterocolitis (NEC) in neonates with rectal bleeding and/or...

Characterizing and Comparing the Profile of Microorganisms From Specific Body Sites and Environmental Surfaces in Newly Disinfected Patient Rooms

Overall Aim: To describe and to assess the change in the temporal profile and transmission of microorganisms between patients and environmental surfaces after admission into a newly disinf...

Host Immune Response to Clostridium Difficile Infection in Inflammatory Bowel Disease Patients

The inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn's disease (CD) are chronic conditions affecting approximately 1.4 million Americans. The burden of Clostridium dif...

PEG-Interferon a-2b + Ribavirin for Treatment of Patients With Chronic Hepatitis C Who Have Previously Failed to Achieve a Sustained Virologic Response Following Interferon Alfa or Interferon a-2b + Ribavirin Therapy

HRN-003 STUDY SYNOPSIS OBJECTIVE: To compare the Sustained Virologic Response (SVR) of PEGIntron plus ribavirin among patients receiving a fixed dose of PEGIntron versus weighted-adjusted...

Medical and Biotech [MESH] Definitions

Immunity, Herd

The non-susceptibility to infection of a large group of individuals in a population. A variety of factors can be responsible for herd immunity and this gives rise to the different definitions used in the literature. Most commonly, herd immunity refers to the case when, if most of the population is immune, infection of a single individual will not cause an epidemic. Also, in such immunized populations, susceptible individuals are not likely to become infected. Herd immunity can also refer to the case when unprotected individuals fail to contract a disease because the infecting organism has been banished from the population.

Pelvic Infection

Infection involving the tissues or organs in the PELVIS.

Abdominal Wall

The outer margins of the ABDOMEN, extending from the osteocartilaginous thoracic cage to the PELVIS. Though its major part is muscular, the abdominal wall consists of at least seven layers: the SKIN, subcutaneous fat, deep FASCIA; ABDOMINAL MUSCLES, transversalis fascia, extraperitoneal fat, and the parietal PERITONEUM.

Hiv-associated Lipodystrophy Syndrome

Defective metabolism leading to fat maldistribution in patients infected with HIV. The etiology appears to be multifactorial and probably involves some combination of infection-induced alterations in metabolism, direct effects of antiretroviral therapy, and patient-related factors.

Subcutaneous Tissue

Loose connective tissue lying under the DERMIS, which binds SKIN loosely to subjacent tissues. It may contain a pad of ADIPOCYTES, which vary in number according to the area of the body and vary in size according to the nutritional state.

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