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Neuropathic Pain - Biotech, Pharma and Life Science Channel

06:06 EDT 24th May 2013 | BioPortfolio

PubMed Articles [ 5442 Associated PubMed Articles listed on BioPortfolio]

Intrapartum sacral stress fracture due to pregnancy-related osteoporosis: a case report.

Low back pain (LBP) and hip pain frequently occur during pregnancy and postpartum period. Although pelvic and mechanic lesions of the soft tissues are most responsible for the etiology, sacral fractur...

Neurotropin inhibits axonal transport in cultured mouse dorsal root ganglion neurons.

Axonal transport is a basic neuronal cell function and important for the supply of materials that maintain neuronal cells, and any increase or decrease in axonal transport expresses the state of neuro...

Spinal neuroimmune activation inhibited by repeated administration of pioglitazone in rats after L5 spinal nerve transection.

Neuroimmune activation contributes to the generation and maintenance of neuropathic pain after peripheral nerve injury. Peroxisome proliferator activated receptor gamma (PPAR-γ) agonists have potenti...

A minocycline derivative reduces nerve injury-induced allodynia, LPS-induced prostaglandin E2 microglial production and signaling via toll-like receptors 2 and 4.

Many studies have shown that minocycline, an antibacterial tetracycline, suppresses experimental pain. While minocycline's positive effects on pain resolution suggest that clinical use of such drugs m...

Negative beliefs and psychological disturbance in spine surgery patients: a cause or consequence of a poor treatment outcome?

PURPOSE: Chronic musculoskeletal pain is often associated with psychological distress and maladaptive beliefs and these are sometimes reported to have a negative impact on surgical outcome. The influe...

Clinical management of masticatory muscle pain : An update of the recommendations.

Besides the different forms of odontalgia, myalgias of the masticatory muscles are the most frequent noninfectious complaints in the orofacial region. After summarizing the recommendations set forth b...

Pain in Neonates.

Gender-Related Difference in Postoperative Pain After Laparoscopic Roux-En-Y Gastric Bypass in Morbidly Obese Patients.

Some evidence exist to suggest that women experience more pain and require more medication than men to achieve a similar state of analgesia. However, this was not studied in morbidly obese patients. T...

Efficacy and Safety of Low Dose Subcutaneous Diclofenac in the Management of Acute Pain: A Randomized Double-Blind Trial.

OBJECTIVE: Diclofenac is an effective and well-tolerated nonsteroidal anti-inflammatory drug (NSAID) frequently used in the treatment of acute pain. Marketed formulations for parenteral administration...

Concern for Pain in the Pre-Operative Period- Is the Internet Being Used for Information By Patients?

OBJECTIVES: This study was conducted to provide information regarding prevalence of pain, type of provider managing pain, and use of Internet for information regarding pain, among patients coming for...

News Articles [ 4745 Associated News Articles listed on BioPortfolio]

Knee Pain Treatment | How “Total Knee Health” Helps People Heal Their Knee Pain Quickly and Effectively – Health Review

Total Knee Health developed by Martin Koban is a newly updated knee pain treatment book that helps people improve all requirements for knee health. A full Total Knee Health review on the site HealthRe...

Algea Therapies introduces SHIELD Vertebral Compression Fracture System

Algea Therapies, a division of Globus Medical Inc. (NYSE: GMED), committed to finding innovative, minimally invasive solutions that treat pain and restore quality of life, today announced the launch o...

[Clinical Picture] Bullosis diabeticorum

A 60-year-old man with history of uncontrolled diabetes mellitus was admitted for investigation of back pain. 2 days after his admission, an overnight spontaneous eruption of a 9×4 cm, tense, non-ten...

Itch And Pain Have Separate Brain Circuits

US scientists have found a molecule that triggers the sensation of itching in mice. They say the finding solves a mystery about itching: it is not a low level of pain but a separately wired circuit w...

Gender Differences In The Prescribing Of Analgesics In Spain

Regardless of pain, social class or age, a woman is more likely to be prescribed pain-relieving drugs. A study published in Gaceta Sanitaria (Spanish health scientific journal) affirms that this pheno...

Socioeconomic Factors Affect Satisfaction Following Knee Replacement Surgery

Knee replacement surgery is a very common procedure. However, it does not always resolve function or pain in all the recipients of new knees. A study by Robert Barrack, MD and his colleagues from the...

Sugar water injections may help ease knee pain

NEW YORK (Reuters Health) - Knee pain appears to decrease up to one year after "prolotherapy," a series of sugar water injections at the site of the pain, according to a new study.

Complimentary X-Rays with Chiropractic Exam Deal Announced by Berlin Chiropractic

Berlin Chiropratic is pleased to announce they will be having a special in which their patients will receive complimentary x-rays when they come in for their chiropractic exam. Taylorsville, UT (PRWEB...

An Itch Is Not a Low-Level Form of Pain

From Nature magazine [More]

J&J expects 10-plus new drug applications by 2017

(AP)—Johnson & Johnson is developing what could eventually be game-changing treatments for depression and pain, and it's aiming to apply for approval of more than 10 new medicines by 2017, executive...

Events [0 Results]

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Companies [ 148 Associated Companies listed on BioPortfolio]

THE Surgical Hospital of Phoenix

THE Surgical Hospital of Phoenix, the first licensed surgical specialty facility of its kind in Arizona, first opened its doors in May of 2005. Specializing in spine, orthopedics,...

RS Medical

RS Medical is the premier provider of non-invasive medical products designed to relieve pain and improve function. The company sells its products including the RS-4i Sequential St...

Targeted Medical Pharma, Inc.

Physician Therapeutics is a division of Targeted Medical Pharma, Inc., a specialty pharmaceutical company that develops and sells prescription medical foods to physi...

Dolor Technologies LLC

Dolor Technologies LLC is dedicated to the development of pain management and drug delivery devices. In the U.S., Dolor Technologies currently offers SphenoCath through regional d...

National Fibromyalgia & Chronic Pain Association

NFMCPA, a not-for-profit organization, supports individuals living with fibromyalgia and other chronic pain illnesses by raising awareness through community outreach, education, a...

The Apothecary Shops

The Apothecary Shops is one of the foremost chains of independent full-service pharmacies with specialties in veterinary medicine, infectious disease, oncology, ophthalmology, fer...

Anesthesia Business Consultants, LLC

ABC, established in 1979, is one of the largest billing and practice management companies dedicated to the complex and intricate specialty of anesthesia and pain management. It is...

Zalicus Inc

Zalicus focuses its internal drug development efforts on pain and immuno-inflammatory diseases. Our pipeline for pain includes Exalgo™ (hydromorphone HCl) extended-release ta...

SpiderTech

SpiderTech provides specialized kinesiology taping products that naturally reduce pain and restore strength and mobility to injured and sore muscles. The Toronto-based company has...

Zynex Inc.

Zynex, Inc. (founded in 1996) engineers, manufactures, markets and sells its own design of electrotherapy medical devices in two distinct markets: standard digital electrotherapy...

Clinical Trials [ 2167 Associated Clinical Trials listed on BioPortfolio]

A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-181)(COMPLETED)

The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.

Pelvic Pain in Women With Endometriosis

This study will examine pelvic pain associated with endometriosis and explore better approaches to treatment. In women with endometriosis, uterine tissue grows outside the uterus. Standa...

Quality of Life and Pain Outcomes Following Video-Assisted Thoracic Surgery (VATS) Anatomic Lung Resection Versus Thoracotomy and Anatomic Lung Resection

The purpose of this study is to see if different types of surgery for lung cancer have different effects on quality of life and pain. What we learn from this study may help us find new way...

Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain

Noxious stimuli occurring intraoperatively and postoperatively generate central sensitization, decreasing pain thresholds and ultimately increasing analgesic requirements. The pathophysiol...

Neuropathic Pain Study With Botulinum Toxin A in Spinal Cord Injury Patients

The purpose of this study is to determine whether botulinum toxin A is effective in the treatment of neuropathic pain in spinal cord injury patients.

USG Nerve Blocks for ACL Reconstruction

Anterior cruciate ligament reconstruction is a routine surgical procedure. Traditional femoral/sciatic block combinations effectively reduce postoperative pain, but results in considerable...

Low-level Laser Therapy on Temporomandibular Disorder

The purpose of this study is to assess the effect of low-level laser on pain, occlusal contacts, mandibular movements and electromyography activity in the masseter and temporal muscles in...

Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury

Imprimis Pharmaceuticals is investigating a proprietary, topical cream formulation consisting of 10% ketoprofen (containing 100 mg of ketoprofen in 1gram of cream) for the local treatment...

The Impact of Genotype on Plasma and Cerebral Spinal Fluid Pharmacokinetics of Celecoxib in Children

Background: Celecoxib is effective for reducing postoperative pain in adults. Children use celecoxib more rapidly than adults and require higher doses. Celecoxib is partially metabolized...

A Study to Compare the Ultrasound-guided Fascia Iliaca Compartment Block (FICB) to Surgeon-placed Fascia Iliaca Compartment Block for Post-operative Pain Control in Patients Undergoing an Anterior Hip Replacement Surgery.

Surgical trauma causes nerve sensitization leading to amplification and prolongation of postoperative pain. In experimental studies, pre-injury neural blockade using local anesthetics has...

Medical and Biotech [MESH] Definitions

Fasciitis, Plantar

Inflammation of the thick tissue on the bottom of the foot (plantar fascia) causing HEEL pain. The plantar fascia (also called plantar aponeurosis) are bands of fibrous tissue extending from the calcaneal tuberosity to the TOES. The etiology of plantar fasciitis remains controversial but is likely to involve a biomechanical imbalance. Though often presenting along with HEEL SPUR, they do not appear to be causally related.

Metatarsalgia

Pain in the region of the METATARSUS. It can include pain in the METATARSAL BONES; METATARSOPHALANGEAL JOINT; and/or intermetatarsal joints (TARSAL JOINTS).

Cholecystitis, Acute

Acute inflammation of the GALLBLADDER wall. It is characterized by the presence of ABDOMINAL PAIN; FEVER; and LEUKOCYTOSIS. Gallstone obstruction of the CYSTIC DUCT is present in approximately 90% of the cases.

Irritable Bowel Syndrome

A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.

Receptor, Bradykinin B2

A constitutively expressed subtype of bradykinin receptor that may play a role in the acute phase of the inflammatory and pain response. It has high specificity for intact forms of BRADYKININ and KALLIDIN. The receptor is coupled to G-PROTEIN, GQ-G11 ALPHA FAMILY and G-PROTEIN, GI-GO ALPHA FAMILY signaling proteins.

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