NonHodgkin lymphoma - Biotech, Pharma and Life Science Channel
PubMed Articles
Despite the well-defined role of autologous haematopoietic stem cell transplantation (autoHCT) in the treatment of patients with relapsed or refractory Hodgkin lymphoma (HL), relapse remains the main...
The microenvironment of human follicular lymphoma (FL), an incurable B cell non-Hodgkin's lymphoma, is thought to play a major role in its pathogenesis and course. Microenvironmental cells of likely i...
Lymphoma is one of the most common forms of cancer in dogs as it is in humans but, unlike humans, the cure rates in canines are still very low. Despite the fact that high grade B-cell lymphomas are co...
Down-regulation of microRNA-29c is associated with renal failure in multiple myeloma.
Suprasellar lymphoma masquerading as tuberculosis of the central nervous system.
Exposures to multiple pesticides and the risk of Hodgkin lymphoma in Canadian men.
PURPOSE: To determine the risk of Hodgkin lymphoma (HL) associated with exposures to multiple pesticides grouped by various classes, including carcinogenic classifications. METHODS: Data collected in...
Nasolacrimal duct tumours in the era of endoscopic dacryocystorhinostomy: literature review.
Background: Nasolacrimal duct tumours are rare and are often found inadvertently during dacryocystorhinostomy. Anecdotal case reports have been published, mostly in ophthalmology journals. Since the e...
Primary Cutaneous CD4+ Small to Medium-Size Pleomorphic T-Cell Lymphoma in a 12-Year-Old Girl.
Primary cutaneous CD4+ small to medium-size pleomorphic T-cell lymphoma (PCSM-TCL) is a rare disease that has been added as a provisional entity to the World Health Organization European Organization...
Data for 125 patients with cytogenetically normal acute myeloid leukemia (CN-AML) regarding BAALC and combinatorial molecular markers at diagnosis were evaluated. Fewer patients with higher BAALC expr...
News Articles
WHITE PLAINS, N.Y., June 19, 2013 /PRNewswire/ -- This year alone, The Leukemia & Lymphoma Society (LLS) is supporting more than 300 research projects with one goal in mind: Discovering lifes...
WHITE PLAINS, N.Y. , June 19, 2013 /- This year alone, The Leukemia & Lymphoma Society (LLS) is supporting more than 300 research projects with one goal in mind: Discovering lifesaving thera...
Incidence Rate of Breast Cancer in Young Women
To the Editor: Dr Johnson and colleagues concluded that there has been a significant increase in the incidence of ER+ breast cancer with distant involvement for women aged 25 to 39 years between 1976...
NEW YORK, June 19, 2013 (GLOBE NEWSWIRE) -- TG Therapeutics, Inc. (Nasdaq:TGTX), an innovative, clinical-stage biopharmaceutical company focused on the acquisition, development and commercialization...
'Night Stalker' killer Richard Ramirez died of cancer
LOS ANGELES (Reuters) - The California serial killer known as the "Night Stalker," who died this month at age 53 while on death row for a mid-1980s reign of terror in the Los Angeles area, succumbed t...
Gilead reports interim ORR data for idelalisib
Gilead Sciences Inc. (NASDAQ:GILD) reported interim data showing twice-daily oral idelalisib led to an overall response rate (ORR), the primary endpoint, of 53.6% in the Phase II Study 101-09 to treat...
Positive Ph II results for Gilead's idelalisib in refractory indolent non-Hodgkin's lymphoma
US biotech firm Gilead Sciences (Nasdaq: GILD) today (June 17) announced encouraging interim results from a single-arm, open-label Phase II study (Study 101-09) evaluating idelalisib (formerly GS-1101...
NORTH CHICAGO, Ill., June 17, 2013 /PRNewswire/ -- AbbVie (NYSE: ABBV) today announced preliminary results from a Phase I study of ABT-199/GDC-0199, an investigational BCL-2 (B-cell lymphoma 2) s...
-- 53.6 Percent Overall Response Rate and Median Duration of Response of 11.9 Months in Heavily Pre-Treated Patients -- -- Data to be Presented at the International Confe...
Events
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Companies
Eutropics Pharmaceuticals Inc.
Eutropics is addressing the need for improving the treatment of aggressive forms of leukemia, myeloma, lymphoma, and other cancers. The company is developing a novel diagnostic te...
Nimbus Discovery is applying advances in computer-based drug discovery to develop new medicines against important drug targets and thereby unlock fundamental biological pathways....
The Leukemia & Lymphoma Society and Reliant Energy
The Leukemia & Lymphoma Society ® (LLS) is the worldâs largest voluntary health agency dedicated to blood cancer. The LLS mission: Cure leukemia, lymphoma, Hodgkinâ...
Yaupon Therapeutics, a privately held, specialty pharmaceutical company, is developing a proprietary gel formulation of mechlorethamine hydrochloride for the treatment of early st...
Ceptaris Therapeutics, Inc. is a privately held, specialty pharmaceutical company that is developing a proprietary gel formulation of mechlorethamine hydrochloride for the treatme...
Shape Pharmaceuticals, Inc. is developing SHP-141, a novel, topical, âsoft-drugâ HDAC inhibitor for the treatment of patients with cutaneous T cell lymphoma (CTCL) and p...
Biovest International, Inc. is an emerging leader in the field of active personalized immunotherapies targeting life-threatening cancers of the blood system. Developed in collabor...
Allos Therapeutics, Inc. (Nasdaq: ALTH) is a biopharmaceutical company committed to the development and commercialization of innovative anti-cancer therapeutics. Allos is currentl...
Xencor, Inc. engineers superior biotherapeutics using its proprietary Protein Design Automation® technology platform, and is a leader in the field of antibody engineering to si...
Gamida Cell is a world leader in stem cell population expansion technologies and stem cell therapy products for transplantation and regenerative medicine. The companyâs pipel...
Clinical Trials
Stem Cell Collection With Ofatumumab
The goal of this clinical research study is to learn if it is possible to collect stem cells after ofatumumab and chemotherapy treatment. This study will also evaluate side-effects, number...
Background: - Studies conducted at the National Cancer Institute suggest that certain chemotherapy drugs may be more effective if given by continuous infusion into the vein rather...
RATIONALE: Herpesvirus is found in the cancer cells of patients with primary effusion lymphoma. Antiviral drugs, such as zidovudine and valganciclovir, may be able to act against the herpe...
RATIONALE: Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and he...
RATIONALE: Drugs used in chemotherapy, such as vorinostat, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Vorinos...
Rituximab and Gemcitabine for Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Rituximab has been demonstrated to sensitize drug-resistant NHL cells to the cytotoxic actions of several chemotherapy agents by enhancing sensitivity of tumor cells to chemotherapy-induce...
Aim of the study is to assess the therapeutic activity and safety of the combination of Chlorambucil and Rituximab in MALT lymphomas and to determine whether the addition of Rituximab to C...
Development of an Evaluation Method of Elderly Condition in Patient Receiving Chemotherapy Treatment
Number of elderly people over 70 is increasing in France. In 2002, in the south-west, 273,741 of them were over 75 years, i.e. 9.2% of Aquitaine population. Incidence of cancer in this old...
Patients with acute lymphoblastic leukaemia or very aggressive lymphoma and documented isolated CNS relapse or CNS relapse combined with other relapse sites should receive therapy with int...
In this study the efficacy and tolerability of two approaches to treat and prevent hyperuricemia is tested in patients with acute lymphoblastic leukemia or high-grade lymphoma with high ri...
Videos
Non-Hodgkin Lymphoma
Doctor Bayard L. Powell, M.D., Section Chief - Hematology & Oncology of Wake Forest Baptist Health discusses Non-Hodgkin Lymphoma and the risk factors, diagn...
Medical and Biotech [MESH] Definitions
Candida Tropicalis
A species of MITOSPORIC FUNGI that is a major cause of SEPTICEMIA and disseminated CANDIDIASIS, especially in patients with LYMPHOMA; LEUKEMIA; and DIABETES MELLITUS. It is also found as part of the normal human mucocutaneous flora.
Oncogene Protein V-cbl
An oncoprotein from the Cas NS-1 murine retrovirus that induces pre- B-CELL LYMPHOMA and MYELOID LEUKEMIAS. v-cbl protein is a tyrosine-phosphorylated, truncated form of its cellular homologue, PROTO-ONCOGENE PROTEIN C-CBL.
Oncogene Protein V-akt
A viral oncoprotein originally isolated from a murine T CELL LYMPHOMA infected with the acutely transforming retrovirus AKT8. v-akt protein is the viral homologue of PROTO-ONCOGENE PROTEINS C-AKT.
Proto-oncogene Proteins C-bcl-6
A DNA-binding protein that represses GENETIC TRANSCRIPTION of target genes by recruiting HISTONE DEACETYLASES. Aberrant Blc-6 expression is associated with certain types of human B-CELL LYMPHOMA.
Precursor Cell Lymphoblastic Leukemia-lymphoma
A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
