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Nonproliferative retinopathy - Biotech, Pharma and Life Science Channel

08:18 EDT 19th April 2014 | BioPortfolio

PubMed Articles [212 Associated PubMed Articles listed on BioPortfolio]

The molecular mechanisms underpinning the therapeutic properties of oleanolic acid, its isomer and derivatives for type 2 diabetes and associated complications.

Recent research has uncovered the molecular mechanisms responsible for the therapeutic properties of oleanolic acid (OA), its isomer ursolic acid (UA), and derivatives. In particular, recent reports h...

Elevated neurofilament light chain (NFL) mRNA levels in prediabetic peripheral neuropathy.

Evidence suggests that peripheral nerve injury occurs during the early stages of disease with mild glycemic dysregulation. Two proteins, neuron-specific enolase (NSE) and neurofilament light chain (NF...

PACAP Application Improves Functional Outcome of Chronic Retinal Ischemic Injury in Rats-Evidence From Electroretinographic Measurements.

Retinoprotective effects of pituitary adenylate cyclase activating polypeptide (PACAP) are well-known and have been demonstrated in various pathological conditions, such as diabetic retinopathy, excit...

ANNALS EXPRESS: Association of serum and vitreous levels of osteoprotegerin with diabetic retinopathy.

Anorexia nervosa complicated by diabetes mellitus: The case for permissive hyperglycemia.

The coexistence of Type 1 Diabetes Mellitus and anorexia nervosa results in an increased incidence of known diabetic complications such as retinopathy and nephropathy, presumably because blood glucose...

Full Depth Imaging: a New Imaging Technique Using Optical Coherence Tomography (OCT).

Purpose: The aim of this study was to evaluate the full depth imaging (FDI) mode as a new acquisition technique with spectral domain (SD) optical coherence tomography (OCT) from Heidelberg Engineering...

Preserve the (intraocular) environment: the importance of maintaining normal oxygen gradients in the eye.

Oxygen levels in the eye are generally low and tightly regulated. Oxygen enters the eye largely by diffusion from retinal arterioles and through the cornea. In intact eyes, oxygen from the retinal art...

Ocular Anti-VEGF Therapy for Diabetic Retinopathy: Overview of Clinical Efficacy and Evolving Applications.

Ocular anti-vascular endothelial growth factor (VEGF) therapy represents one of the most significant advances in modern medicine. The introduction and widespread use of ocular anti-VEGF therapy for ag...

Ocular Anti-VEGF Therapy for Diabetic Retinopathy: The Role of VEGF in the Pathogenesis of Diabetic Retinopathy.

Diabetic retinopathy is the leading cause of visual impairment and preventable blindness, and represents a significant socioeconomic cost for health care systems worldwide. Therefore, new approaches b...

Fibulin 2, a tyrosine O-sulfated protein, is up-regulated following retinal detachment.

Retinal detachment is the physical separation of the retina from the retinal pigment epithelium. It occurs during aging, trauma or during a variety of retinal disorders such as age-related macular deg...

News Articles [93 Associated News Articles listed on BioPortfolio]

Discovery could have far-reaching implications for diagnosis and treatment of diabetic retinopathy

Indiana University researchers have detected new early-warning signs of the potential loss of sight associated with diabetes. This discovery could have far-reaching implications for the diagnosis and...

EyePromise® Eye Vitamins Supports Women's Eye Health and Eye Safety Month

ST. LOUIS, April 17, 2014 /PRNewswire/ -- Did you know women are more likely to suffer from visual impairments like Age-related Macular Degeneration, Glaucoma, Diabetic Retinopathy, and Cataracts than...

New technique detects microscopic diabetes-related eye damage

(Indiana University) Indiana University researchers have detected new early-warning signs of the potential loss of sight associated with diabetes. This discovery could have far-reaching implications f...

Fewer ophthalmologists equals less diabetic eye care

(HealthDay)—In areas with less access to ophthalmologists, fewer individuals with diabetes, diabetic retinopathy, and age-related macular degeneration (ARMD) receive care, according to a study publi...

Dr. Thomas Ciulla is recognized among Castle Connolly's Top Doctors® for Indianapolis, IN region in 2014.

INDIANAPOLIS, April 11, 2014 /PRNewswire-USNewswire/ -- Castle Connolly Medical Ltd., America's trusted source for identifying Top Doctors, has selected Indianapolis's Ophthalmology specialist Dr. Tho...

U.S. Ophthalmic Surgical Systems Market

WEST HARTFORD, Conn., April 10, 2014 /PRNewswire-iReach/ -- Global Information Inc. announces the addition of a new market research report "U.S. Ophthalmic Surgical Systems Market" at GIIResearch.com...

Fluorescein Angiography Details Vasculature in ROP

The imaging procedure demonstrates subtle changes in vasculature in bevacizumab-treated eyes with retinopathy of prematurity (ROP), but must be performed by a skilled photographer for optimal results....

New report documents cardiopulmonary arrest in premature infant after cyclomydril eyedrops

Eyedrops administered to infants as part of routine outpatient retinopathy of prematurity (ROP) screening can have life-threatening consequences. A case report published in the current issue of the Jo...

Report describes cardiopulmonary arrest in infant following cyclopentolate eyedrops

Eyedrops administered to infants as part of routine outpatient retinopathy of prematurity (ROP) screening can have life-threatening consequences. A case report published in the current issue of the Jo...

Report documents cardiopulmonary arrest in premature infant after cyclomydril eyedrops

(Elsevier Health Sciences) Eyedrops administered to infants as part of routine outpatient retinopathy of prematurity screening can have life-threatening consequences. A case report published in the cu...

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Companies [6 Associated Companies listed on BioPortfolio]

Allegro Ophthalmics, LLC

With more than 100 years of combined experience in vision science and medicine, the leadership team at Allegro Ophthalmics, LLC is establishing Integrin Peptide Therapy as the...

Promedior, Inc.

Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...

Acucela Inc.

Acucela Inc. is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for treating blinding eye di...

NormOxys, Inc.

NormOxys is developing a novel class of small molecule drugs, oxyrens, which enhance the body’s ability to deliver oxygen more efficiently to diseased tissues with oxygen def...

Acucela

Acucela Inc. (www.acucela.com) is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for...

Optos plc

Optos plc is a leading medical retinal imaging technology company. Both eye and non-eye diseases often first exhibit in the periphery of the retina. These are very difficult to de...

Clinical Trials [165 Associated Clinical Trials listed on BioPortfolio]

Intravitreal Long Acting Gas in the Prevention of Early Postoperative Vitreous Hemorrhage in Diabetic Vitrectomy

Recurrent vitreous hemorrhage after vitrectomy for complications of diabetic retinopathy is a common occurrence. The hemorrhage may appear within the first few weeks after surgery or month...

Ocular Blood Flow in Early Glaucoma Patients Before and After Treatment With Dorzolamide

Impaired ocular blood flow is an important risk factor in the pathogenesis of primary open angle glaucoma (POAG). A few studies suggest that topical dorzolamide 2% may increase optic nerve...

Improving Metabolic Assessments in Type 1 Diabetes Mellitus Clinical Trials

OBJECTIVE: This study is being conducted by the Type 1 Diabetes TrialNet Study Group, funded by the National Institutes of Health, in collaboration with the European C-Peptide Group. The...

A Novel Acuity Testing Method

The purpose of this protocol is to develop a valid, reliable, better standardized, and more efficient test of visual acuity (ability to see fine details) for use in clinical trials. Recent...

Blood Factors and Diabetic Retinopathy

This study will determine whether certain factors in the blood are associated with the severity of diabetic retinopathy. Patients age 10 years and older with diabetes mellitus and diabeti...

Phase II Randomized Controlled Study of Sequential Orbital Radiotherapy for Graves' Ophthalmopathy

OBJECTIVES: I. Evaluate the effects of 20 Gy of external-beam radiotherapy to 1 orbit vs. the untreated orbit at 3 and 6 months after therapy in patients with Graves' ophthalmopathy. II....

Screening for Studies on Retinovascular Diseases

This screening protocol is designed to help recruit patients for National Eye Institute (NEI) studies of the retina, such as diabetic retinopathy and macular degeneration. Patients must me...

Diabetic Retinopathy Study (DRS)

To determine whether photocoagulation helps prevent severe visual loss from proliferative diabetic retinopathy. To determine whether a difference exists in the efficacy and safety of argo...

Diabetic Retinopathy Vitrectomy Study (DRVS)

To compare two therapies, early vitrectomy and conventional management, for recent severe vitreous hemorrhage secondary to diabetic retinopathy. Conventional management includes vitrectom...

Krypton-Argon Regression of Neovascularization Study (KARNS)

To evaluate whether red krypton laser treatment is as effective at causing regression of diabetic disc neovascularization as treatment with the blue-green argon laser, when both lasers are...

Medical and Biotech [MESH] Definitions

A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Degenerative changes to the RETINA due to HYPERTENSION.

A drug used to reduce hemorrhage in diabetic retinopathy.

Removal of the whole or part of the vitreous body in treating endophthalmitis, diabetic retinopathy, retinal detachment, intraocular foreign bodies, and some types of glaucoma.

Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

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