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Nonproliferative retinopathy - Biotech, Pharma and Life Science Channel

14:10 EDT 27th May 2016 | BioPortfolio

PubMed Articles [293 Associated PubMed Articles listed on BioPortfolio]

Use and abuse of anti-angiogenic drugs for Retinopathy of Prematurity treatment in Argentina, 2015.

Dicarbonyl Stress Mimics Diabetic Neurovascular Damage in the Retina.

The net effect of euglycemic treatment is grossly overestimated in diabetes mellitus and retinopathy, similar to what is observed in diabetic individuals, is found in the absence of chronic hyperglyce...

Antivascular endothelial growth factor in the treatment of retinopathy of prematurity.

To review the most recent literature regarding the clinical experience of antivascular endothelial growth factor (anti-VEGF) therapies in the treatment of retinopathy of prematurity (ROP).

Association between Von Willebrand factor, disintegrin and metalloproteinase with thrombospondin type 1 motif member 13, d-Dimer and cystatin C levels with retinopathy in type 1 diabetes mellitus.

We evaluated the association between plasma levels of VWF, ADAMTS13 and d-Dimer, which consist on endothelial dysfunction and hypercoagulability biomarkers, and cystatin C with retinopathy in type 1 d...

Impaired RBC deformability is associated with diabetic retinopathy in patients with type 2 diabetes.

Red blood cell (RBC) deformability, the ability of RBCs to change shape under stress, is known to be decreased in type 2 diabetes (T2D). However, as yet little is known of the association between RBC ...

The Impact of Vision Impairment (IVI) Questionnaire; Validation of the Thai-Version and the Implementation on Vision-Related Quality of Life in Thai Rural Community.

The objective of this study is to validate the Thai-version of the impact of vision impairment (IVI) questionnaire and to evaluate its impact on vision-related quality of life (VRQoL) in southern Thai...

PERIPHERAL RETINOPATHY ASSOCIATED WITH APLASTIC ANEMIA.

To report a case of severe, bilateral, rapidly progressing peripheral retinal nonperfusion associated with underlying aplastic anemia.

Lonicerae Japonicae Flos attenuates diabetic retinopathy by inhibiting retinal angiogenesis.

Lonicerae Japonicae Flos (Jin-Yin-Hua) is a well-known traditional Chinese medicine used for clearing away heat and toxic material.

Localization and segmentation of optic disc in retinal images using circular Hough transform and grow-cut algorithm.

Automated retinal image analysis has been emerging as an important diagnostic tool for early detection of eye-related diseases such as glaucoma and diabetic retinopathy. In this paper, we have present...

Adeno-Associated Virus Overexpression of Angiotensin-Converting Enzyme-2 Reverses Diabetic Retinopathy in Type 1 Diabetes in Mice.

Angiotensin-converting enzyme (ACE)-2 is the primary enzyme of the vasoprotective axis of the renin angiotensin system that regulates the classic renin angiotensin system axis. We aimed to determine w...

News Articles [139 Associated News Articles listed on BioPortfolio]

NeuMedics Invited to Speak at the Life Science Innovation Northwest 2016 in Seattle

CEO Iain Duncan will present the results of several studies on diabetic retinopathies. Seattle, WA. (PRWEB) May 27, 2016 NeuMedics Inc. is pleased to announce that CEO Iain Duncan has been invited to...

Angle closure glaucoma in the Northern Ireland Diabetic Retinopathy Screening Programme

Angle closure glaucoma in the Northern Ireland Diabetic Retinopathy Screening Programme Eye advance online publication, May 27 2016. doi:10.1038/eye.2016.98 Authors: M A Lagan, M K O'Gallag...

Added Benefits Seen With Early Initiation of Anti-VEGF Agents for Diabetic Retinopathy

Dr Charles C. Wykoff reviews recent data showing that more timely treatment has a significant upside. Medscape Ophthalmology

Microvascular disease increases risk for CV events in type 2 diabetes

In adults with type 2 diabetes free of cardiovascular disease, the burden of microvascular disease confers a risk for future cardiovascular events similar to the risks observed from smoking, hypertens...

VIDEO: OCT angiography optimizes treatment for AMD, diabetic retinopathy

PARIS — At the meeting of the French Society of Ophthalmology, Gabriel Coscas, MD, gives his perspective on OCT angiography and its role in optimizing treatment.

Diabetic Retinopathy a Major Threat to Global Health

The Alliance for Aging Research has released The Silver Book®: Diabetic Retinopathy, a factsheet illustrating the impact of this irreversible disease. Washington, D.C. (PRWEB) May 18, 2016 Today...

ThromboGenics Business Update - Q1 2016

LEUVEN, Belgium, May 13, 2016 /PRNewswire/ -- Developing Novel Medicines Targeting Diabetic Eye Disease    Highlights  ThromboGenics is focused on developing novel medicines for th...

Potential new intraocular treatment based on RAS manipulation can prevent or reverse diabetic retinopathy

Pathologic changes of the retina caused by diabetes is the leading cause of blindness in working adults. Diabetic retinopathy has no known cure, treatment options are inadequate, and prevention strate...

Queen's University Belfast to study the Innate Repair Activator ARA 290 in Diabetic Macular Edema

TARRYTOWN, N.Y., May 10, 2016 /PRNewswire/ -- Araim Pharmaceuticals, a clinical stage drug development company with a unique platform technology for activating post-injury tissue repair and ...

Intraocular therapy prevents or reverses diabetic retinopathy in mice

Pathologic changes of the retina caused by diabetes is the leading cause of blindness in working adults. Diabetic retinopathy has no known cure, treatment options are inadequate, and prevention strate...

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Companies [6 Associated Companies listed on BioPortfolio]

Acucela Inc.

Acucela Inc. is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for treating blinding eye di...

Optos plc

Optos plc is a leading medical retinal imaging technology company. Both eye and non-eye diseases often first exhibit in the periphery of the retina. These are very difficult to de...

Promedior, Inc.

Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...

NormOxys, Inc.

NormOxys is developing a novel class of small molecule drugs, oxyrens, which enhance the body’s ability to deliver oxygen more efficiently to diseased tissues with oxygen def...

Acucela

Acucela Inc. (www.acucela.com) is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for...

Allegro Ophthalmics, LLC

With more than 100 years of combined experience in vision science and medicine, the leadership team at Allegro Ophthalmics, LLC is establishing Integrin Peptide Therapy as the ...

Clinical Trials [213 Associated Clinical Trials listed on BioPortfolio]

Infant-parent Skin-to-skin Contact During Screening for Retinopathy

Retinopathy of prematurity (ROP) is a feared complication of premature birth. If discovered in time, the disease can be treated, and impaired vision or blindness can be reduced. Premature ...

A Fatty Acids Study in Preventing Retinopathy of Prematurity

Most fatty acids, important for development and especially the Omega-3 fatty acids for the brain development are transferred in the third trimester with means that in the premature infant ...

Study to Evaluate Effects of Emixustat Hydrochloride in Subjects With Proliferative Diabetic Retinopathy

To evaluate the effects of oral emixustat hydrochloride (emixustat) on aqueous humor biomarkers associated with proliferative diabetic retinopathy (PDR) from baseline to week 12.

Study of the Efficacy and Safety of Intravitreal (IVT) Aflibercept for the Improvement of Moderately Severe to Severe Nonproliferative Diabetic Retinopathy (NPDR)

The primary objective of the study is to assess the efficacy of intravitreal (IVT) aflibercept compared to sham treatment in the improvement of moderately severe to severe nonproliferative...

Studying the Performance of OCT C-scan in the Screening for Retinopathy Related to Synthetic Antimalarials

Maculopathy induced by retinal toxicity of synthetic antimalarials is to be screened at the sub-clinical stage. Indeed, when the first visual symptoms appear, macular damage is already irr...

The Effect of Dopamine on Diabetic Retinopathy

The purpose of this study is to evaluate the use of electroretinogram (ERG) using a novel handheld system, RETeval, and evaluate contrast sensitivity testing in detecting pre-clinical reti...

PRP vs Bevacizumab for PDR Treatment

Protocol S by DRCR.net has shown that receive Ranibizumab as anti-vascular endothelial growth factor (anti-VEGF) therapy with deferred panretinal photocoagulation (PRP) are non-inferior to...

Characteristic Analysis of Retinopathy Associated With High Doses of Interferon α-2b Therapy

The high doses of interferon α-2b therapy in patients with melanomas of the skin may induced retinopathy, especially in the patients with hypertension or diabetes, so these patients shoul...

Pediatric Type 1 Diabetes and Retinopathy

Diabetic retinopathy (DR) causes more new cases of blindness among young adults than any other disease. More than 90% of individuals with type 1 diabetes (T1D) will have some form of DR by...

CMR in Type 2 Diabetes Mellitus Patients

The study will be performed as a cross-sectional survey. 300 Type 2 diabetes patients (T2DM), with or without known cardiovascular disease, will be recruited from the diabetes outpatient c...

Videos

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Medical and Biotech [MESH] Definitions

A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Degenerative changes to the RETINA due to HYPERTENSION.

A drug used to reduce hemorrhage in diabetic retinopathy.

Removal of the whole or part of the vitreous body in treating endophthalmitis, diabetic retinopathy, retinal detachment, intraocular foreign bodies, and some types of glaucoma.

Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

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