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Nonproliferative retinopathy - Biotech, Pharma and Life Science Channel

21:27 EST 22nd January 2017 | BioPortfolio

PubMed Articles [389 Associated PubMed Articles listed on BioPortfolio]

Müller Cell-Microglia Cross Talk Drives Neuroinflammation in Diabetic Retinopathy.

Neuropilin 1 Involvement in Choroidal and Retinal Neovascularisation.

Inhibiting VEGF is the gold standard treatment for neovascular age-related macular degeneration (AMD). It is also effective in preventing retinal oedema and neovascularisation (NV) in diabetic retinop...

Association of Diabetes Related Complications with Heart Rate Variability among a Diabetic Population in the UAE.

Microvascular, macrovascular and neurological complications are the key causes of morbidity and mortality among type II diabetes mellitus (T2DM) patients. The aim of this study was to investigate the ...

Report of 12-months efficacy and safety of intravitreal fluocinalone acetonide implant for the treatment of chronic diabetic macular oedema: a real-world result in the United Kingdom.

PurposeTo report the 12-months visual and anatomical outcomes of chronic diabetic macular oedema (DMO) treated with ILUVIEN in a real-world clinical practice in a single tertiary referral centre.Metho...

Plasma microRNA-21 expression: an indicator for the severity of type 2 diabetes with diabetic retinopathy.

To investigate the roles of plasma microRNA-21 (miR-21) in the pathogenic process of type 2 diabetes (T2D) with diabetic retinopathy (DR).

Retinal sensitivity changes associated with diabetic neuropathy in the absence of diabetic retinopathy.

To explore any relationship between the markers of early retinal neuronal damage and peripheral diabetic neuropathy in subjects with no diabetic retinopathy (DR).

Mini Review: Changes in the Incidence of and Progression to Proliferative and Sight-Threatening Diabetic Retinopathy Over the Last 30 Years.

Diabetic retinopathy is a leading cause of blindness worldwide. The last 3 decades have seen major improvements in glycemic and blood pressure control as well as the introduction of national screening...

Angiogenesis-related genes may be a more important factor than matrix metalloproteinases in bronchopulmonary dysplasia development.

We characterized the expression profile of angiogenesis-related genes (ARG) and matrix metalloproteinase (MMP) genes in preterm infants, with and without bronchopulmonary dysplasia (BPD). We reanalyze...

IGF-1R Regulates the Extracellular Level of Active MMP-2, Pathological Neovascularization, and Functionality in Retinas of OIR Mouse Model.

In ischemic proliferative diseases such as retinopathies, persistent hypoxia leads to the release of numerous neovascular factors that participate in the formation of abnormal vessels and eventually c...

Sub-Category Classifiers for Multiple-Instance Learning and its Application to Retinal Nerve Fiber Layer Visibility Classification.

We propose a novel multiple instance learning method to assess the visibility (visible/not visible) of the retinal nerve fiber layer (RNFL) in fundus camera images. Using only image-level labels, our ...

News Articles [151 Associated News Articles listed on BioPortfolio]

Fluocinolone Implant Slows Retinopathy in Macular Edema

Researchers say fluocinolone implants can delay proliferative diabetic retinopathy and slow progression of diabetic retinopathy in patients with diabetic macular edema. Medscape Medical News

Ophthalmologists advised to weigh costs of diabetic retinopathy treatment

KOLOA, Hawaii — Less expensive alternatives for treating diabetic retinopathy should be explored in some subgroups of patients, according to a speaker here.“This is really a privileged time to hav...

AdAlta receives Orphan Designation for its lead drug candidate targeting patients with idiopathic pulmonary disease

MELBOURNE Australia, 18 January, 2017 - AdAlta Limited (ASX: 1AD), today announced it has received Orphan Drug Designation from the United States Food and Drug Administration (FDA) for AD-114, a nov...

New techniques and treatments show promise for eliminating retinopathy of prematurity

A mini-symposium published in the Journal of the American Association for Pediatric Ophthalmology and Strabismus provides important insights into new techniques and treatments that show promise for el...

How to prevent the microvascular complications of type 2 diabetes beyond glucose control

Microvascular complications (retinopathy, nephropathy, and neuropathy) affect hundreds of millions of patients with type 2 diabetes. They usually affect people with longstanding or uncontrolled...

An eye test for Alzheimer's

Researchers at Macquarie University and Edith Cowan University (ECU) will be the first in NSW and Western Australia, respectively, to have access to a retinal-scanning camera that can identify beta-am...

Retinopathy of prematurity: New developments are cause for hope

(Elsevier Health Sciences) A mini-symposium published in the Journal of the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) provides important insights into new techniques and ...

Evergaze LLC and Dallas Lighthouse for the Blind, Inc. Form Distribution and Customer Support Partnership for seeBoost®

Electro-optical medical device manufacturer Evergaze LLC has entered into a five-year agreement with nonprofit organization Dallas Lighthouse for the Blind to distribute Evergaze ...

Survey: Screening, treatment for ROP lacking in US

Only about half of neonatal intensive care unit medical directors surveyed in a recent study said they felt there were enough ophthalmologists in their service areas to screen for or treat retinopathy...

LKC Technologies' Portable RETeval™ Electrodiagnostic Device and Sensor Strips Earn Two United States Patents

GAITHERSBURG, Md., Jan. 11, 2017 /PRNewswire/ -- LKC Technologies once again leads through innovation as the RETeval™ device, LKC's full function flash ERG/VEP system, was granted a patent (USP...

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Companies [6 Associated Companies listed on BioPortfolio]

Acucela Inc.

Acucela Inc. is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for treating blinding eye di...

Optos plc

Optos plc is a leading medical retinal imaging technology company. Both eye and non-eye diseases often first exhibit in the periphery of the retina. These are very difficult to de...

Promedior, Inc.

Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...

NormOxys, Inc.

NormOxys is developing a novel class of small molecule drugs, oxyrens, which enhance the body’s ability to deliver oxygen more efficiently to diseased tissues with oxygen def...

Acucela

Acucela Inc. (www.acucela.com) is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for...

Allegro Ophthalmics, LLC

With more than 100 years of combined experience in vision science and medicine, the leadership team at Allegro Ophthalmics, LLC is establishing Integrin Peptide Therapy as the ...

Clinical Trials [246 Associated Clinical Trials listed on BioPortfolio]

Determination of Cut-off Value of AGEsP and HbA1c in Type 2 Diabetes Diagnosis in China

Study of the correlation between AGEsP and HbA1c and diabetic retinopathy prevalence: determination of cut-off value of AGEsP and HbA1c in type 2 diabetes diagnosis in China

Clinical Study of Tang Wang Prescription Intervene Diabetic Non-proliferative Retinopathy

This study include 384 Participants with diabetic non-proliferative retinopathy Design Method: Randomized, double blind, placebo controlled and multicenter clinical study. Participants tr...

The Efficacy of Intravitreal Aflibercept Injection in Improvement of Retinal Nonperfusion in Diabetic Retinopathy

Retinal nonperfusion drives vision-threatening complications such as pathological neovascularization, which can lead to neovascular glaucoma, vitreous hemorrhage, or tractional retinal det...

Patient Comfort Using Green vs. Yellow Pan Retinal Photocoagulation

Our aim is to compare patient comfort when using the 532 nanometer (green) wavelength laser to the 577 nanometer (yellow) wavelength laser during pan retinal photocoagulation to treat pati...

Empagliflozin Reduces Progression of Diabetic Retinopathy in Patients With High Risk of Diabetic Macular Edema

This is a prospective, randomized, active control, two-arm parallel, double-blind, monocenter phase IV clinical trial. The trial compares empagliflozin to glimepiride in patients with type...

Safety and Efficacy of Anti-Oxidants and Anti-inflammatory Agents in Glaucoma and Diabetic Retinopathy

This study is a multi-armed protocol designed to evaluate the safety and efficacy of two different combinations of nutritional supplements (study drug) (Glauco-Health and Glauco-Select) ch...

Endolaserless Vitrectomy With Intravitreal IAI for PDR-Related VH

This is a phase I/II open label, randomized, interventional clinical trial. Study eyes will receive one preoperative intravitreal aflibercept injection (IAI) 7 days prior to vitrectomy and...

A Multi-center Study to Evaluate Performance of an Automated Device for the Detection of Diabetic Retinopathy

Diabetes affects 29.1 million people or 9.3% of the population of the United States. Results of a study by the Eye Diseases Prevalence Research Group reveal that 40% of diabetes patients h...

a Population Based Study on Metabolic Syndrome Complications, and Mortality

Metabolic syndrome (MetS) is recognized as clustering of a number of components including hypertension, hypertriglyceridemia, low serum high-density lipoprotein cholesterol (HDL-C), impair...

Early Laser Treatment for Diabetic Eye Disease in China : A Pilot Randomized Trial

To compare immediate laser pan-retinal photocoagulation (PRP) treatment of severe or very severe non proliferative diabetic retinopathy (NPDR) stage versus deferral of treatment until the ...

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Medical and Biotech [MESH] Definitions

A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Degenerative changes to the RETINA due to HYPERTENSION.

A drug used to reduce hemorrhage in diabetic retinopathy.

Removal of the whole or part of the vitreous body in treating endophthalmitis, diabetic retinopathy, retinal detachment, intraocular foreign bodies, and some types of glaucoma.

Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

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