Nonproliferative retinopathy - Biotech, Pharma and Life Science Channel

00:08 EDT 4th May 2016 | BioPortfolio

PubMed Articles [301 Associated PubMed Articles listed on BioPortfolio]

Role of Tamponade in Vitrectomy for Proliferative Diabetic Retinopathy with Vitreous Hemorrhage.

To analyze the role of tamponade in vitrectomy for proliferative diabetic retinopathy with vitreous hemorrhage.

Angiogenesis and Inflammation Crosstalk in Diabetic Retinopathy.

Diabetic retinopathy (DR) is one of the most prevalent microvascular complications of diabetes and one of the most frequent causes of blindness in active age. Etiopathogenesis behind this important co...

Evaluation of Refractive Errors and Ocular Biometric Outcomes after Intravitreal Bevacizumab for Retinopathy of Prematurity.

To assess ocular biometric outcomes following intravitreal bevacizumab (IVB) monotherapy for retinopathy of prematurity (ROP) and compare these results with those of laser photocoagulated infants and ...


To report a case of bilateral retinopathy associated with subacute sclerosing panencephalitis.

Monitoring neovascularization in aggressive posterior retinopathy of prematurity using optical coherence tomography angiography.

Epidemiological aspects of diabetic retinopathy - a bicentric study in Antananarivo, Madagascar - report of 158 cases.

To wake up cancer stem cells, or to let them sleep, that is the question.

Cancer stem cells (CSCs) generate transient-amplifying cells and thereby contribute to cancer propagation. A fuller understanding of the biological features of CSCs is expected to lead to the developm...

Disparities in Adherence to Screening Guidelines for Diabetic Retinopathy in the United States: A Comprehensive Review and Guide for Future Directions.

Diabetic retinopathy (DR) is the leading cause of new-onset blindness in American adults aged 20-74 years old. The number of diabetics living with diagnosed DR increased by 89%, from 4.06 million to 7...

Dual blockade of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (FGF-2) exhibits potent anti-angiogenic effects.

Both vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF or FGF-2) are potent pro-angiogenic factors and play a critical role in cancer development and progression. Clin...

The Economic Model of Retinopathy of Prematurity (EcROP) Screening and Treatment: Mexico and the United States.

To describe an economic (Ec) model for estimating the impact of screening and treatment for retinopathy of prematurity (ROP).

News Articles [138 Associated News Articles listed on BioPortfolio]

Glucose metabolism affects macular thickness in diabetic patients

SEATTLE — Pericentral macular thickness decreased in diabetic patients with worsening glucose metabolism, which may reflect early neurodegenerative changes, according to a poster presented here. “...

Anti-VEGF effective in wet AMD, diabetic retinopathy

SEATTLE — Patients diagnosed with both neovascular age-related macular degeneration and diabetic retinopathy who received intravitreal injections showed stabilization in best-corrected visual acuity...

Vessel damage may precede diabetic retinopathy, researchers find

For many years, scientists believed patients developed retinopathy and, as a result of the damage to the blood vessels, later developed neuropathy. In a new study, however, researchers discovered that...

Researchers find vessel damage may precede diabetic retinopathy

A University of Iowa-led study of diabetes-related vision impairment holds good news—and some bad news—for patients with signs of these disorders.

New Ocriplasmin Research Findings Presented

Leuven, Belgium, April 27, 2016 /PRNewswire/ -- New Data Confirm Appropriate Patient Selection Leads to Improved Treatment Outcomes, With no new Safety Signals Observed  ThromboGenics NV (Eur...

Body Fat Distribution and Diabetic Retinopathy

This commentary discusses a cross-sectional study published in JAMA Ophthalmology that investigated association of body fat distribution with diabetic retinopathy in an Asian population with type 2 di...

Researchers find nerve damage may precede diabetic retinopathy

(University of Iowa Health Care) For many years, scientists believed patients developed retinopathy and, as a result of the damage to the blood vessels, later developed neuropathy. In this new study, ...

Visual Field Needed for Driving Eligibility Preserved After Laser Panretinal Photocoagulation

Multispot laser panretinal photocoagulation (PRP) in proliferative diabetic retinopathy spares visual fields required for driving eligibility, researchers report. Reuters Health Information

Natural history of retinopathy in children and young people with type 1 diabetes

Natural history of retinopathy in children and young people with type 1 diabetes Eye advance online publication, April 22 2016. doi:10.1038/eye.2016.60 Authors: N Dhillon, A Karthikeyan, A ...

Dr Somdutt Prasad at the Scientific Programme of Reticon 2016

Chennai, India, April 20, 2016 --( Top eye surgeon and retinal specialist of Kolkata Dr Somdutt Prasad will be one of the speakers at the scientific programme of Reticon 2016 to be held at H...

Events [0 Results]


Companies [6 Associated Companies listed on BioPortfolio]

Acucela Inc.

Acucela Inc. is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for treating blinding eye di...

Optos plc

Optos plc is a leading medical retinal imaging technology company. Both eye and non-eye diseases often first exhibit in the periphery of the retina. These are very difficult to de...

Promedior, Inc.

Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...

NormOxys, Inc.

NormOxys is developing a novel class of small molecule drugs, oxyrens, which enhance the body’s ability to deliver oxygen more efficiently to diseased tissues with oxygen def...


Acucela Inc. ( is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for...

Allegro Ophthalmics, LLC

With more than 100 years of combined experience in vision science and medicine, the leadership team at Allegro Ophthalmics, LLC is establishing Integrin Peptide Therapy as the ...

Clinical Trials [212 Associated Clinical Trials listed on BioPortfolio]

A Fatty Acids Study in Preventing Retinopathy of Prematurity

Most fatty acids, important for development and especially the Omega-3 fatty acids for the brain development are transferred in the third trimester with means that in the premature infant ...

Study to Evaluate Effects of Emixustat Hydrochloride in Subjects With Proliferative Diabetic Retinopathy

To evaluate the effects of oral emixustat hydrochloride (emixustat) on aqueous humor biomarkers associated with proliferative diabetic retinopathy (PDR) from baseline to week 12.

Study of the Efficacy and Safety of Intravitreal (IVT) Aflibercept for the Improvement of Moderately Severe to Severe Nonproliferative Diabetic Retinopathy (NPDR)

The primary objective of the study is to assess the efficacy of intravitreal (IVT) aflibercept compared to sham treatment in the improvement of moderately severe to severe nonproliferative...

Studying the Performance of OCT C-scan in the Screening for Retinopathy Related to Synthetic Antimalarials

Maculopathy induced by retinal toxicity of synthetic antimalarials is to be screened at the sub-clinical stage. Indeed, when the first visual symptoms appear, macular damage is already irr...

The Effect of Dopamine on Diabetic Retinopathy

The purpose of this study is to evaluate the use of electroretinogram (ERG) using a novel handheld system, RETeval, and evaluate contrast sensitivity testing in detecting pre-clinical reti...

PRP vs Bevacizumab for PDR Treatment

Protocol S by has shown that receive Ranibizumab as anti-vascular endothelial growth factor (anti-VEGF) therapy with deferred panretinal photocoagulation (PRP) are non-inferior to...

Characteristic Analysis of Retinopathy Associated With High Doses of Interferon α-2b Therapy

The high doses of interferon α-2b therapy in patients with melanomas of the skin may induced retinopathy, especially in the patients with hypertension or diabetes, so these patients shoul...

Pediatric Type 1 Diabetes and Retinopathy

Diabetic retinopathy (DR) causes more new cases of blindness among young adults than any other disease. More than 90% of individuals with type 1 diabetes (T1D) will have some form of DR by...

CMR in Type 2 Diabetes Mellitus Patients

The study will be performed as a cross-sectional survey. 300 Type 2 diabetes patients (T2DM), with or without known cardiovascular disease, will be recruited from the diabetes outpatient c...

Enteral Administration of Docosahexaenoic Acid to Prevent Retinopathy of Prematurity

The purpose of this study is to evaluate whether docosahexaenoic acid given by enteral feeding prevent retinopathy of prematurity and/or diminish its severity in preterm infants.


None available.

Medical and Biotech [MESH] Definitions

A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Degenerative changes to the RETINA due to HYPERTENSION.

A drug used to reduce hemorrhage in diabetic retinopathy.

Removal of the whole or part of the vitreous body in treating endophthalmitis, diabetic retinopathy, retinal detachment, intraocular foreign bodies, and some types of glaucoma.

Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

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