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Nonproliferative retinopathy - Biotech, Pharma and Life Science Channel

08:52 EST 23rd February 2017 | BioPortfolio

PubMed Articles [392 Associated PubMed Articles listed on BioPortfolio]

Blocking IL-17A Alleviates Diabetic Retinopathy in Rodents.

Interleukin (IL)-17A, a proinflammatory cytokine, has been implicated in several autoimmune diseases. However, it is unclear whether IL-17A is involved in diabetic retinopathy (DR), one of the most se...

Discharge outcomes of patients referred to specialist eye clinic from diabetic retinopathy screening in Northland (2014-15).

To determine the discharge outcomes of patients seen in specialist eye clinic after referral from diabetic retinopathy screening (DRS).

Prevalence of diabetic retinopathy at first presentation to the retinal screening service in the greater Wellington region of New Zealand 2006-2015, and implications for models of retinal screening.

To describe the prevalence of diabetic retinopathy (DR) in patients at first presentation for diabetic retinal screening in the greater Wellington region with the intent of service evaluation.

Long-term survival following diabetic vitrectomy.

To update long-term survival data on patients with proliferative diabetic retinopathy undergoing vitrectomy and to identify associated risk factors.

Impaired nephrogenesis in neonatal rats with oxygen-induced retinopathy.

Preterm neonates are born while nephrogenesis is ongoing and are commonly exposed to factors in a hyperoxic environment that can impair renal development. Oxidative stress has also been implicated in ...

Optical Coherence Tomographic Angiography in Type 2 Diabetes and Diabetic Retinopathy.

Optical coherence tomographic angiography (OCT-A) is able to visualize retinal microvasculature without the need for injection of fluorescein contrast dye. Nevertheless, it is only able to capture a l...

FGF21 Administration Suppresses Retinal and Choroidal Neovascularization in Mice.

Pathological neovascularization, a leading cause of blindness, is seen in retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration. Using a mouse model of hypoxia-driven ...

Retinopathy of prematurity: A comprehensive risk analysis for prevention and prediction of disease.

Retinopathy of prematurity (ROP) is a blinding morbidity of preterm infants. Our current screening criteria have remained unchanged since their inception and lack the ability to identify those at grea...

Binocular sensitivity and specificity of screening tests in cross-sectional diagnostic studies of paired organs.

We introduce new binocular accuracy measures as alternatives to conventional marginal measures that can be used to evaluate screening tests in diagnostic studies involving paired organs (e.g. eyes and...

CHOROIDAL THICKNESS IN DIABETIC RETINOPATHY ASSESSED WITH SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY.

To compare the choroidal thickness (CT) of diabetic eyes (different stages of disease) with controls, using swept-source optical coherence tomography.

News Articles [133 Associated News Articles listed on BioPortfolio]

Alimera Sciences and Knight Therapeutics Announce Filing of New Drug Submission for Iluvien(R) in Canada

ATLANTA, GEORGIA and MONTREAL, QUEBEC -- (Marketwired) -- 02/22/17 -- Alimera Sciences, Inc. (NASDAQ: ALIM) (Alimera), a leader in research, development and commercialization of prescription ophthal...

American Diabetes Association® Issues Diabetic Retinopathy Position Statement

ARLINGTON, Va., Feb. 21, 2017 /PRNewswire-USNewswire/ -- Diabetes affects the entire body and can result in long-term complications, including damage to the small blood vessels. Such damage can lead t...

First ADA Guidance on Diabetic Retinopathy in 15 Years

Since the ADA's last guidelines on diabetic retinopathy in 2002, advances have included widespread use of optical coherence tomography, wide-field fundus photography, and intravitreous anti-VE...

IBM Research is training Watson to identify eye retina abnormalities

MELBOURNE, Australia, Feb. 21, 2017 /PRNewswire/ -- IBM (NYSE: IBM) Research has today announced new research developments in IBM Watson's ability to detect abnormalities of the eye's retina...

IRIS and CoxHealth honored as recipients of the 2017 Microsoft Health Innovation Awards

PENSACOLA, FL--(Marketwired - February 21, 2017) - Intelligent Retinal Imaging Systems (IRIS) and CoxHealth today announced the two organizations have been named recipients of Microsoft Corp.'s 2017 H...

Ophthalmic Devices Market Global Briefing 2017Including: Vision Care Devices, Cataract Surgery Devices , Refractive Surgery Devices, and Diagnostic and Monitoring Ophthalmic Devices Covering: Essilor International, Alcon Novartis, Johnson Johnson, Abbott

Ophthalmic devices are an aid in the diagnosis, monitoring, surgery and treatment of various eye related diseases such as cataract, agerelated macular degeneration, glaucoma, diabetic retinopathy, ret...

Global Ophthalmics Partnering 20102017: Deal trends, players and financials [Updated: 01022017] Prices from USD $2995

Global Ophthalmics Partnering 2010 to 2017 provides the full collection of Ophthalmics disease deals signed between the world's pharmaceutical and biotechnology companies since 2010. Trends in Ophthal...

Researchers explore effects of preeclampsia on risk of developing ROP in premature infants

Mary Elizabeth Hartnett, MD, and colleagues at the John A. Moran Center and Department of Pediatrics at the University of Utah and Children's Hospital of Wisconsin, were looking for a way to tease apa...

Two-drug combination shows promise against diabetic retinopathy in animal models

A two-drug cocktail provided better protection against diabetes-related vision loss than a single drug during testing in rat models, a team of University of Florida Health and Dutch researchers has fo...

Is preeclampsia a risk or a protective factor in retinopathy of prematurity?

(University of Utah Health Sciences) Mary Elizabeth Hartnett, MD, and colleagues at the John A. Moran Center and Department of Pediatrics at the University of Utah and Children's Hospital of Wisconsin...

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Companies [6 Associated Companies listed on BioPortfolio]

Acucela Inc.

Acucela Inc. is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for treating blinding eye di...

Optos plc

Optos plc is a leading medical retinal imaging technology company. Both eye and non-eye diseases often first exhibit in the periphery of the retina. These are very difficult to de...

Promedior, Inc.

Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...

NormOxys, Inc.

NormOxys is developing a novel class of small molecule drugs, oxyrens, which enhance the body’s ability to deliver oxygen more efficiently to diseased tissues with oxygen def...

Acucela

Acucela Inc. (www.acucela.com) is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for...

Allegro Ophthalmics, LLC

With more than 100 years of combined experience in vision science and medicine, the leadership team at Allegro Ophthalmics, LLC is establishing Integrin Peptide Therapy as the ...

Clinical Trials [248 Associated Clinical Trials listed on BioPortfolio]

Antioxidant Use in Diabetes to Reduce Oxidative Stress

Dietary supplementation with antioxidant vitamins, such as Vitamin C and Vitamin E, reduces malformation rates in embryos of diabetic animals. However, human trials exploring the benefits ...

a Prospective Cohort Study for Propranolol Treatment in Retinopathy of Prematurity

The purpose of this study is to evaluate the safety and efficacy of oral/local propranolol in preterm newborns who diagnosed as early phase of retinopathy of prematurity (ROP).

Determination of Cut-off Value of AGEsP and HbA1c in Type 2 Diabetes Diagnosis in China

Study of the correlation between AGEsP and HbA1c and diabetic retinopathy prevalence: determination of cut-off value of AGEsP and HbA1c in type 2 diabetes diagnosis in China

Clinical Study of Tang Wang Prescription Intervene Diabetic Non-proliferative Retinopathy

This study include 384 Participants with diabetic non-proliferative retinopathy Design Method: Randomized, double blind, placebo controlled and multicenter clinical study. Participants tr...

The Efficacy of Intravitreal Aflibercept Injection in Improvement of Retinal Nonperfusion in Diabetic Retinopathy

Retinal nonperfusion drives vision-threatening complications such as pathological neovascularization, which can lead to neovascular glaucoma, vitreous hemorrhage, or tractional retinal det...

Patient Comfort Using Green vs. Yellow Pan Retinal Photocoagulation

Our aim is to compare patient comfort when using the 532 nanometer (green) wavelength laser to the 577 nanometer (yellow) wavelength laser during pan retinal photocoagulation to treat pati...

Empagliflozin Reduces Progression of Diabetic Retinopathy in Patients With High Risk of Diabetic Macular Edema

This is a prospective, randomized, active control, two-arm parallel, double-blind, monocenter phase IV clinical trial. The trial compares empagliflozin to glimepiride in patients with type...

Safety and Efficacy of Anti-Oxidants and Anti-inflammatory Agents in Glaucoma and Diabetic Retinopathy

This study is a multi-armed protocol designed to evaluate the safety and efficacy of two different combinations of nutritional supplements (study drug) (Glauco-Health and Glauco-Select) ch...

Endolaserless Vitrectomy With Intravitreal IAI for PDR-Related VH

This is a phase I/II open label, randomized, interventional clinical trial. Study eyes will receive one preoperative intravitreal aflibercept injection (IAI) 7 days prior to vitrectomy and...

A Multi-center Study to Evaluate Performance of an Automated Device for the Detection of Diabetic Retinopathy

Diabetes affects 29.1 million people or 9.3% of the population of the United States. Results of a study by the Eye Diseases Prevalence Research Group reveal that 40% of diabetes patients h...

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Medical and Biotech [MESH] Definitions

A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Degenerative changes to the RETINA due to HYPERTENSION.

A drug used to reduce hemorrhage in diabetic retinopathy.

Removal of the whole or part of the vitreous body in treating endophthalmitis, diabetic retinopathy, retinal detachment, intraocular foreign bodies, and some types of glaucoma.

Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

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