Nonproliferative retinopathy - Biotech, Pharma and Life Science Channel

12:56 EDT 2nd September 2014 | BioPortfolio

PubMed Articles [300 Associated PubMed Articles listed on BioPortfolio]

Comparison of iridocorneal angle in infants with retinopathy of prematurity and healthy infants using spectral domain optical coherence tomography.

To compare measurements and morphologic characteristics of the iridocorneal angle in preterm infants with retinopathy of prematurity (ROP) and healthy infants using spectral domain optical coherence t...

Carcinoma-associated retinopathy in a young teenager with immature teratoma of the ovary.

A 14-year-old African American girl presented with diminished vision in both eyes 1 week after undergoing an oophorectomy for a right ovarian mass. Systemic metastatic work-up was negative. Visual acu...

Genetics of Diabetic Retinopathy.

Diabetic retinopathy (DR) is a polygenic disorder. Twin studies and familial aggregation studies have documented clear familial clustering. Heritability has been estimated to be as high as 27 % for a...

Evaluating the association of autonomic drug use to the development and severity of retinopathy of prematurity.

To explore the association of autonomic agents with the development and severity of retinopathy of prematurity (ROP).

Development of an Experimental Model of Proliferative Retinopathy by Intravitreal Injection of VEGF165.

Abstract Purpose: To develop an experimental model of proliferative retinopathy by intravitreal injection of vascular endothelial growth factor 165 (VEGF165) in pigmented rabbits. Methods: A prospecti...

Pharmacokinetics and local safety profile of propranolol eye drops in rabbits.

Background.Oral propranolol, a non-selective ß-blocker, is able to reduce the progression of retinopathy of prematurity in newborns, but it appeared unsafe. This study aimed to find, in rabbits, a pr...

Cellular responses following retinal injuries and therapeutic approaches for neurodegenerative diseases.

Retinal neurodegenerative diseases like age-related macular degeneration, glaucoma, diabetic retinopathy and retinitis pigmentosa each have a different etiology and pathogenesis. However, at the cellu...

Preliminary Anatomical and Neurodevelopmental Outcomes of Intravitreal Bevacizumab As Adjunctive Treatment for Retinopathy of Prematurity.

Abstract Purpose: To evaluate the two-year follow-up of patients with type 1 retinopathy of prematurity (ROP) who received intravitreal bevacizumab (IVB) as adjunctive treatment. Materials and methods...

Notch signaling functions in retinal pericyte survival.

Purpose: Pericytes, the vascular cells that constitute the outer layer of capillaries, have been shown to play a crucial role in vascular development and stability. Loss of pericytes precedes endothel...

Elevated Soluble VEGF Receptor sFlt-1 Correlates with Endothelial Injury in IgA Nephropathy.

Endothelial injury, which may present clinically as hypertension, proteinuria and increased von Willebrand Factor (vWF) level, is a common manifestation in IgA nephropathy (IgAN). However, causal fact...

News Articles [112 Associated News Articles listed on BioPortfolio]

Allergan Announces OZURDEX® (dexamethasone 700 mcg intravitreal implant in applicator) Now Approved in the European Union for the Treatment of Diabetic Macular Edema

Allergan, Inc. (NYSE: AGN) announced today that the European Commission has extended the Marketing Authorization for OZURDEX® (dexamethasone 700 mcg intravitreal implant in appli...

Molecular probes permit doctors to detect diabetic retinopathy before vision fails

(Federation of American Societies for Experimental Biology) A new study published in the September issue of The FASEB Journal identifies a novel strategy to diagnose the leading cause of blindness in ...

Well Versed Ophthalmologist Irina Pankova, DO, MD, FAOCO, Widely Acclaimed for Her Skills in Glaucoma Treatment inside The Leading Physicians of the World

Board certified ophthalmologist, Irina Pankova, DO, MD, FAOCO, is being honored for her extraordinary  passion and enduring dedication by representing the ophthalmology specialists of New York with i...

Diabetic Retinopathy Global Clinical Trials Review, H1, 2014

LONDON, Aug. 26, 2014 /PRNewswire/ -- Reportbuyer.com has added a new market research report:Diabetic Retinopathy Global Clinical Trials Review, H1, 2014http://www.reportbuyer.com/pharma_healthca...

Fundus Cameras Market: Product Type- Mydriatic, Non-Mydriatic, Hybrid and ROP Cameras; End Users- Hospitals, Ophthalmology Clinics and Ophthalmic & Optometrist Offices

Transparency Market Research published a new report "Fundus Cameras Market: Global Industry Analysis, Size, Volume, Share, Growth, Trends and Forecast 2014 - 2019" to its report store. (PRWE...

Native American ancestry a risk factor for eye disease

Native American ancestry is a significant risk factor for vision-threatening diabetic retinopathy among Latinos with type 2 diabetes, a new study shows for the first time. Using genetic assays and det...

Study shows Native American ancestry a risk factor for eye disease

New research led by the University of Southern California (USC) Eye Institute, part of Keck Medicine of USC, shows for the first time that Native American ancestry is a significant risk factor for vis...

USC Eye Institute study shows Native American ancestry a risk factor for eye disease

(University of Southern California - Health Sciences) New research from the University of Southern California Eye Institute, part of Keck Medicine of University of Southern California, shows for the f...

KalVista Pharmaceuticals Announces Start of Clinical Development for Novel Treatment for Diabetic Macular Edema

SOUTHAMPTON, England, August 20, 2014 /PRNewswire/ -- Phase I Trial of Plasma Kallikrein Inhibitor to be Conducted in the US  KalVista Pharmaceuticals ("KalVista"), an ophthalmology company wit...

Retinopathy and CKD as Predictors of All-Cause and CVD Mortality

Are patients with CKD and retinopathy at an increased risk for cardiovascular mortality? This new study investigates the connection. American Journal of Kidney Diseases

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Companies [6 Associated Companies listed on BioPortfolio]

Optos plc

Optos plc is a leading medical retinal imaging technology company. Both eye and non-eye diseases often first exhibit in the periphery of the retina. These are very difficult to de...

Promedior, Inc.

Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...

NormOxys, Inc.

NormOxys is developing a novel class of small molecule drugs, oxyrens, which enhance the body’s ability to deliver oxygen more efficiently to diseased tissues with oxygen def...

Acucela Inc.

Acucela Inc. is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for treating blinding eye di...

Acucela

Acucela Inc. (www.acucela.com) is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for...

Allegro Ophthalmics, LLC

With more than 100 years of combined experience in vision science and medicine, the leadership team at Allegro Ophthalmics, LLC is establishing Integrin Peptide Therapy as the ...

Clinical Trials [166 Associated Clinical Trials listed on BioPortfolio]

Near Infrared Photobiomodulation Treatment for Diabetic Macular Oedema

This pilot study aims to establish that treatment with near infrared light (NIR) reduces diabetic macular oedema in patients suffering diabetic retinopathy by exerting a positive beneficia...

Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity (the STOP-ROP Multicenter Trial)

To test the efficacy, safety, and costs of providing supplemental oxygen in moderately severe retinopathy of prematurity (prethreshold ROP).

Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) - Outcome Study of Cryotherapy for Retinopathy of Prematurity

To determine the safety and efficacy of trans-scleral cryotherapy of the peripheral retina in certain low birth-weight infants with retinopathy of prematurity (ROP) for reducing blindness ...

Sorbinil Retinopathy Trial (SRT)

To evaluate the safety and efficacy of the investigational drug sorbinil, an aldose reductase inhibitor, in preventing the development of diabetic retinopathy and neuropathy in persons wit...

Krypton-Argon Regression of Neovascularization Study (KARNS)

To evaluate whether red krypton laser treatment is as effective at causing regression of diabetic disc neovascularization as treatment with the blue-green argon laser, when both lasers are...

Early Treatment Diabetic Retinopathy Study (ETDRS)

To evaluate the effectiveness of both argon laser photocoagulation and aspirin therapy in delaying or preventing progression of early diabetic retinopathy to more severe stages of visual l...

Diabetic Retinopathy and Visual Function Study

The purpose of this study is to evaluate possible mechanisms of central visual loss in patients with diabetes mellitus. The visual loss of interest to be investigated is that associated w...

Long-Term Follow-Up of Patients Enrolled in the Early Treatment Diabetic Retinopathy Study (ETDRS)

Patients enrolled in the original Early Treatment Diabetic Retinopathy Study at the Clinical Center at Johns Hopkins Wilmer Eye Institute will be invited for a follow-up visit at the Natio...

Blood Factors and Diabetic Retinopathy

This study will determine whether certain factors in the blood are associated with the severity of diabetic retinopathy. Patients age 10 years and older with diabetes mellitus and diabeti...

Retinal Arteriolar Abnormalities and CV Mortality

To determine whether retinal arteriolar changes (generalized narrowing, focal narrowing and arterio-venous nicking) and retinopathy were associated with 10-year stroke-and ischemic heart ...

Medical and Biotech [MESH] Definitions

A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Degenerative changes to the RETINA due to HYPERTENSION.

A drug used to reduce hemorrhage in diabetic retinopathy.

Removal of the whole or part of the vitreous body in treating endophthalmitis, diabetic retinopathy, retinal detachment, intraocular foreign bodies, and some types of glaucoma.

Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

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