Nonproliferative retinopathy - Biotech, Pharma and Life Science Channel

08:01 EDT 24th October 2014 | BioPortfolio

PubMed Articles [268 Associated PubMed Articles listed on BioPortfolio]

Side-effects and complications of laser treatment in diabetic retinal disease.

ABSTRACT Laser treatment for diabetic retinopathy was the first intraocular treatment to provide a highly effective means for preventing visual loss in patients with diabetes. Although inherently dest...

Cataract surgery and its complications in diabetic patients.

Abstract Diabetic patients are known to have an increased risk of cataract development and cataract surgery is a common surgical procedure for diabetic individuals. Cataract extraction (CE) in diabeti...

Vitreous and Plasma VEGF Levels as Predictive Factors in the Progression of Proliferative Diabetic Retinopathy after Vitrectomy.

To investigate the vitreous and plasma levels of vascular endothelial growth factor (VEGF) in patients with proliferative diabetic retinopathy (PDR) and to determine whether they predict a disease pro...

Potential Role of Cyr61 Induced Degeneration of Human Müller Cells in Diabetic Retinopathy.

The degeneration of Müller cells has been recognized to involve in the pathogenesis of diabetic retinopathy. However, the mechanism is not yet clear. This study is to explore the potential role of Cy...

Perfluorocarbon in vitreoretinal surgery and preoperative bevacizumab in diabetic tractional retinal detachment.

To describe the en bloc perfluorodissection (EBPD) technique and to demonstrate the applicability of using preoperative intravitreal bevacizumab during small-gauge vitreoretinal surgery (23-gauge tran...

Targeting inflammation in diabetes: Newer therapeutic options.

Inflammation has been recognised to both decrease beta cell insulin secretion and increase insulin resistance. Circulating cytokines can affect beta cell function directly leading to secretory dysfunc...

Low Birth Weight Is a Risk Factor for Severe Retinopathy of Prematurity Depending on Gestational Age.

To evaluate the impact of low birth weight as a risk factor for retinopathy of prematurity (ROP) that will require treatment in correlation with gestational age at birth (GA).

Intravitreal Bevacizumab in Acute Central/Hemicentral Retinal Vein Occlusions: Three-Year Results of a Prospective Clinical Study.

Abstract Purpose: To prospectively evaluate the effects of intravitreal bevacizumab (IVB, Avastin; Genentech, Inc., San Francisco, CA) injections in patients with acute central/hemicentral retinal vei...

Angiogenic Potential of Vitreous from Proliferative Diabetic Retinopathy and Eales' Disease Patients.

Proliferative Diabetic Retinopathy (PDR) and Eales' Disease (ED) have different aetiologies although they share certain common clinical symptoms including pre-retinal neovascularization. Since there i...

Overexpression of CD163 in vitreous and fibrovascular membranes of patients with proliferative diabetic retinopathy: possible involvement of periostin.

To determine whether CD163, a specific marker for M2 macrophages, is involved in the formation of preretinal fibrovascular membranes (FVMs) present in eyes with proliferative diabetic retinopathy (PDR...

News Articles [129 Associated News Articles listed on BioPortfolio]

New Study Forecasts Number of Diabetic Eye Disease Cases to Reach Nearly 11 Million by 2032

Prevent Blindness Calls on Public Health Agencies to Increase Attention to Diabetic Eye Disease CHICAGO (PRWEB) October 23, 2014 Public health agencies across the country are feeling the impact from ...

Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes

ST. LOUIS, Oct. 21, 2014 /PRNewswire-USNewswire/ -- Early symptoms of diabetic eye and vision disorders are often subtle or unnoticed, but new technology, coupled with yearly, comprehensive eye e...

iPhone Ophthalmoscope Rivals Traditional Methods for Diabetic Eye Disease Monitoring

Study shows iPhone ophthalmoscope could be an effective, lower-cost solution for monitoring diabetic retinopathy in remote populationsRead more about iPhone Ophthalmoscope Rivals Traditional Methods f...

EYLEA injection shows better gains in visual acuity than both bevacizumab and ranibizumab in NIH-sponsored DME study

Regeneron Pharmaceuticals, has announced that in the National Institutes of Health (NIH) sponsored, Diabetic Retinopathy Clinical Research Network comparative effectiveness study in patients with Diab...

Regeneron's Eylea trumps rivals in NIH study

Regeneron is claiming victory after a US-government sponsored trial has suggested its eye treatment Eylea is superior to its rivals in treating diabetic macular oedema.The US company has seized on the...

American Academy of Ophthalmology Announces Key Milestones for Ocular Disease Database, a National Quality of Care Initiative

SAN FRANCISCO, Oct. 19, 2014 /PRNewswire-USNewswire/ -- The American Academy of Ophthalmology today announced key milestones in the development of an innovative quality of care initiative launched les...

Smartphone Approach for Examining Progression of Diabetic Eye Disease Offers Comparable Results to Traditional Method

CHICAGO, Oct. 18, 2014 /PRNewswire/ -- A smartphone-based tool may be an effective alternative to traditional ophthalmic imaging equipment in evaluating and grading severity of a diabetic eye disease,...

Cataract Surgeon and Ophthalmologist from Hawaii Worldster Lee, MD, Honored for His Longstanding Career in The Leading Physicians of the World

As a result of impeccable passion for medicine and determination to reach excellence in all aspects of patient care, Worldster Lee, MD, has been selected to receive publication in The Leading Physicia...

ACT boosted on stem cell results

Advanced Cell Technology Inc. (OTCBB:ACTC) held most of the gain it picked up ahead of Wednesday's online publication of data from a pair of Phase I/II trials showing visual improvements in patients t...

Significant Retinopathy Risk With Long-Term Hydroxychloroquine

Long-term use of hydroxychloroquine may carry a significant risk of toxic retinopathy, according to a retrospective case-control study. Reuters Health Information

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Companies [6 Associated Companies listed on BioPortfolio]

Acucela Inc.

Acucela Inc. is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for treating blinding eye di...

Optos plc

Optos plc is a leading medical retinal imaging technology company. Both eye and non-eye diseases often first exhibit in the periphery of the retina. These are very difficult to de...

Promedior, Inc.

Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...

NormOxys, Inc.

NormOxys is developing a novel class of small molecule drugs, oxyrens, which enhance the body’s ability to deliver oxygen more efficiently to diseased tissues with oxygen def...

Acucela

Acucela Inc. (www.acucela.com) is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for...

Allegro Ophthalmics, LLC

With more than 100 years of combined experience in vision science and medicine, the leadership team at Allegro Ophthalmics, LLC is establishing Integrin Peptide Therapy as the ...

Clinical Trials [169 Associated Clinical Trials listed on BioPortfolio]

Phenotypes of Nonproliferative Diabetic Retinopathy in DM 2 Patients Identified by OCT, CFP, RLA and mfERG (DIAMARKER)

To characterise phenotypes of Non Proliferative Diabetic Retinopathy (NPDR) progression using multimodal testing/imaging procedures.

Intravitreal Aflibercept Injection for Radiation Retinopathy

The purpose of this study is to assess the safety of intravitreal aflibercept injection - in the treatment of macular edema associated with retinopathy secondary to previous radiation ther...

Effects of Caloric Restriction in Obesity and Type 2 Diabetes

The study investigates whether a long-term 25% caloric restriction can prevent onset and/or progression of renal function deterioration, retinal involvement and cardiovascular complication...

Near Infrared Photobiomodulation Treatment for Diabetic Macular Oedema

This pilot study aims to establish that treatment with near infrared light (NIR) reduces diabetic macular oedema in patients suffering diabetic retinopathy by exerting a positive beneficia...

Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity (the STOP-ROP Multicenter Trial)

To test the efficacy, safety, and costs of providing supplemental oxygen in moderately severe retinopathy of prematurity (prethreshold ROP).

Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) - Outcome Study of Cryotherapy for Retinopathy of Prematurity

To determine the safety and efficacy of trans-scleral cryotherapy of the peripheral retina in certain low birth-weight infants with retinopathy of prematurity (ROP) for reducing blindness ...

Sorbinil Retinopathy Trial (SRT)

To evaluate the safety and efficacy of the investigational drug sorbinil, an aldose reductase inhibitor, in preventing the development of diabetic retinopathy and neuropathy in persons wit...

Krypton-Argon Regression of Neovascularization Study (KARNS)

To evaluate whether red krypton laser treatment is as effective at causing regression of diabetic disc neovascularization as treatment with the blue-green argon laser, when both lasers are...

Early Treatment Diabetic Retinopathy Study (ETDRS)

To evaluate the effectiveness of both argon laser photocoagulation and aspirin therapy in delaying or preventing progression of early diabetic retinopathy to more severe stages of visual l...

Diabetic Retinopathy and Visual Function Study

The purpose of this study is to evaluate possible mechanisms of central visual loss in patients with diabetes mellitus. The visual loss of interest to be investigated is that associated w...

Medical and Biotech [MESH] Definitions

A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Degenerative changes to the RETINA due to HYPERTENSION.

A drug used to reduce hemorrhage in diabetic retinopathy.

Removal of the whole or part of the vitreous body in treating endophthalmitis, diabetic retinopathy, retinal detachment, intraocular foreign bodies, and some types of glaucoma.

Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

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