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Nonproliferative retinopathy - Biotech, Pharma and Life Science Channel

00:45 EDT 21st August 2017 | BioPortfolio

PubMed Articles [377 Associated PubMed Articles listed on BioPortfolio]

Altered Expression Profile of Circular RNAs in the Serum of Patients with Diabetic Retinopathy Revealed by Microarray.

Diabetic retinopathy (DR) is the leading cause of blindness among working age adults. Circular RNAs (circRNAs) are a kind of noncoding RNAs that are involved in the development of some diseases. Here,...

Retinopathy and optic atrophy: Expanding the phenotypic spectrum of pathogenic variants in the AARS2 gene.

Optic atrophy may be the sequela of optic nerve injury due to any insult, including isolated and syndromic genetic diseases. Alanyl-tRNA synthetase 2 (AARS2) pathogenic variants have been reported to ...

Presumed Solar Retinopathy in Child With Juvenile Open-Angle Glaucoma.

Technique of retinal gene therapy: delivery of viral vector into the subretinal space.

PurposeSafe and reproducible delivery of gene therapy vector into the subretinal space is essential for successful targeting of the retinal pigment epithelium (RPE) and photoreceptors. The success of ...

The validity of self-report of eye diseases in participants with vision loss in the National Eye Health Survey.

We assessed the validity and reliability of self-report of eye disease in participants with unilateral vision loss (presenting visual acuity worse than 6/12 in the worse eye and equal to or better tha...

CDKAL1 rs7756992 is associated with diabetic retinopathy in a Chinese population with type 2 diabetes.

Diabetic retinopathy (DR) is a major microvascular complication of diabetes. Susceptibility genes for type 2 diabetes may also impact the susceptibility of DR. This case-control study investigated the...

ROCK-1 mediates diabetes-induced retinal pigment epithelial and endothelial cell blebbing: Contribution to diabetic retinopathy.

In diabetic retinopathy, the exact mechanisms leading to retinal capillary closure and to retinal barriers breakdown remain imperfectly understood. Rho-associated kinase (ROCK), an effector of the sma...

The joint effect of the endothelin receptor B gene (EDNRB) polymorphism rs10507875 and nitric oxide synthase 3 gene (NOS3) polymorphism rs869109213 in Slovenian patients with type 2 diabetes mellitus and diabetic retinopathy.

Increasing evidence suggests that endothelin and nitric oxide synthase genes and their products exert biological effects on the vasculature via the nitric oxide or endothelin pathway. The aim of the s...

Unusual retinopathy in a child with severe combined immune deficiency.

We describe a case of an infant diagnosed with severe combined immune deficiency (Adenosine Deaminase (ADA), SCID) with severe retinopathy and associated low vision in both eyes at first examination. ...

An intronic LINE-1 insertion in MERTK is strongly associated with retinopathy in Swedish Vallhund dogs.

The domestic dog segregates a significant number of inherited progressive retinal diseases, several of which mirror human retinal diseases and which are collectively termed progressive retinal atrophy...

News Articles [169 Associated News Articles listed on BioPortfolio]

Ophthalmology Devices Global Market Forecast To 2021 [Report Updated: 03072015] Prices from USD $4500

Ophthalmology is a segment of medical science associated with study of anatomy, physiology, diseases of human eye, and developing various therapeutic methods to treat eye diseases. Some of the major e...

Greater extent of edema associated with worse visual acuity

BOSTON — Patients with diabetic macular edema who experienced a greater extent of edema at 52 weeks post-ranibizumab treatment experienced worse anatomic response compared with patients with less ex...

Eclipse 2017: Here Comes the Solar Retinopathy

Despite all the warnings, patients may view the solar eclipse without proper protection. Be on alert for signs and symptoms of solar retinopathy, says a specialist. Medscape Optometry

Anti-VEGF Treatment May Not Stop Diabetic Retinopathy

Not all patients with diabetic retinopathy benefit from treatment with vascular endothelial growth-factor (VEGF) inhibitors, new research confirms. Medscape Medical News

Global Ophthalmic Lasers Market Expected to Grow at 5.9% CAGR From 2014 to 2025: Million Insights

FELTON, California, August 17, 2017 /PRNewswire/ -- The global ophthalmic lasers market size was worth USD 1.0 billion in 2016, whichis anticipated to grow at a CAGR of more than 5.9% during the f...

Ophthalmic Drugs Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2017 - 2025

LONDON, Aug. 16, 2017 /PRNewswire/ -- Global Ophthalmic Drugs Market: Overview Ophthalmic drugs is a growing market driven by rising prevalence of intraocular eye disorders mainly in elderly popu...

HealPros and BioIQ Collaborate to Deliver a Comprehensive Diabetes Care Gap Closure Solution to Help Health Plans Improve Quality Ratings

HealPros, a technology-enabled company providing HEDIS and STAR improvement programs, and BioIQ, a technology platform driving the employer and health plan shift to ...

Ophthalmologists Worry About Eclipse Viewing

The solar eclipse that will be visible in the United States on August 21 could cause solar retinopathy if viewers don't take precautions, specialists warn. Medscape Medical News

Aerpio Reports Second Quarter 2017 Financial Results

Commenced Trading on the OTCQB® Market Continue to Dose Patients in the TIME-2b Clinical Trial of AKB-9778 in Patients with Diabetic Retinopathy ...

Retina Physicians Urge Caution and Offer Safety Tips for Viewing the 'Great American Eclipse' on August 21

CHICAGO, Aug. 14, 2017 /PRNewswire-USNewswire/ -- On Monday, August 21st, the United States will witness the largest total solar eclipse in nearly 100 years, and the American Society of Retina Special...

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Companies [7 Associated Companies listed on BioPortfolio]

Aerpio Pharmaceuticals, Inc.

Aerpio Pharmaceuticals, Inc. is a biopharmaceutical company focused on advancing first-in-class treatments for ocular diseases. The Company’s lead program, AKB‐9778, is ...

Acucela Inc.

Acucela Inc. is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for treating blinding eye di...

Optos plc

Optos plc is a leading medical retinal imaging technology company. Both eye and non-eye diseases often first exhibit in the periphery of the retina. These are very difficult to de...

Promedior, Inc.

Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...

NormOxys, Inc.

NormOxys is developing a novel class of small molecule drugs, oxyrens, which enhance the body’s ability to deliver oxygen more efficiently to diseased tissues with oxygen def...

Acucela

Acucela Inc. (www.acucela.com) is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for...

Allegro Ophthalmics, LLC

With more than 100 years of combined experience in vision science and medicine, the leadership team at Allegro Ophthalmics, LLC is establishing Integrin Peptide Therapy as the ...

Clinical Trials [270 Associated Clinical Trials listed on BioPortfolio]

Preventing Chronic Lung Disease in Extremely Premature Infants

The purpose of this study is to determine if an investigational drug can reduce respiratory complications in extremely premature babies through 12 months corrected age (CA), as compared to...

Medico-economic Comparison Between Treatment With Panretinal Photocoagulation by Laser in 1 Session Versus 4 Sessions in Diabetic Retinopathy

Despite the fact that the efficacy of a single session of multispot laser has been demonstrated in the treatment of patients with diabetic retinopathy as compared with four sessions of sin...

A Study That Tests BI 1467335 in Patients With Diabetic Eye Disease (Diabetic Retinopathy). It Looks at the Way BI 1467335 is Taken up, the Effects it Has, and How Well it is Tolerated.

The main objective is to evaluate ocular and systemic safety and tolerability of BI 1467335 as well as whether BI 1467335 monotherapy has a potential to improve retinal lesions in patients...

Steroids for Early Treatment of Radiation Retinopathy

Radiation retinopathy is a known complication of ocular radiation therapy. To date there is no known effective treatment. In addition to their anti-vascular endothelial growth factor (VEGF...

The Study of the Internet Monitoring and Analysis of Exercise to Reduce the Complications of Diabetic Kidney Disease

Microvascular complications are a major complication of diabetes.Diabetic microvascular complications can not only lead to chronic kidney disease and retinopathy, but also affect the quali...

Multi-Center Study to Determine the Role of Fatty Acids in Serum in Preventing Retinopathy of Prematurity (MDM)

The study is a Randomized Intervention, Multi-Center Study to Determine the Role of Fatty Acids in Serum and Breast Milk in preventing Retinopathy of Prematurity Subjects who meet all incl...

The TIME-2b Study: A Study of AKB-9778, a Novel Tie 2 Activator, in Patients With Non-Proliferative Diabetic Retinopathy (NPDR)

The purpose of this study is to evaluate the safety and efficacy of subcutaneously administered AKB-9778 15mg once daily or 15mg twice daily for 12 months in patients with moderate to seve...

Effectiveness of Pharmacotherapy Follow-up Care in Outpatients With Type 2 Diabetes Mellitus

Hypothesis: Pharmacotherapy follow-up can improve clinical outcomes of outpatients with type 2 diabetes mellitus. Methods: In this single blind, placebo-controlled trial, the participants...

Hypothyroidism in Patients With Type 2 Diabetes With Early Diabetic Nephropathy

Diabetes Mellitus is the most common disorder seen. The impact of this disease on the quality of life, and on morbidity and mortality through the complications that affect the small and la...

Effect of E Balance Pro Therapy on Diabetes and Related Complications

This is an observational study, to test the hypothesis that E Balance Pro Therapy micro-current treatments, delivered with precision in amplitude, waveform and pulsing pattern, adapted by ...

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Medical and Biotech [MESH] Definitions

A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Degenerative changes to the RETINA due to HYPERTENSION.

A drug used to reduce hemorrhage in diabetic retinopathy.

Removal of the whole or part of the vitreous body in treating endophthalmitis, diabetic retinopathy, retinal detachment, intraocular foreign bodies, and some types of glaucoma.

Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

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