Nonproliferative retinopathy - Biotech, Pharma and Life Science Channel

21:35 EST 29th January 2015 | BioPortfolio

PubMed Articles [299 Associated PubMed Articles listed on BioPortfolio]

A Novel Curvature Based Algorithm for Automatic Grading of Retinal Blood Vessel Tortuosity.

Tortuosity of retinal blood vessels is an improtant symptom of diabetic retinopathy or retinopathy of prematurity. In this paper, we propose an automatic image based method for measuring single vessel...

Evaluation of the Accuracy of Grading Indirect Ophthalmoscopy Video Images for Retinopathy of Prematurity Screening.

To determine whether digital retinal images obtained using a video indirect ophthalmoscopy system can be accurately graded for zone, stage of retinopathy of prematurity (ROP), and plus or pre-plus dis...

Dual effects of the fatty acid receptor 'GPR40' for human health.

Free fatty acid receptor 'GPR40' is expressed predominantly in the wide variety of neurons of the central nervous system and ß-cells in the pancreatic islets. Since its deorphanization in 2003, the p...

DHA Inhibited AGEs-Induced Retinal Microglia Activation Via Suppression of the PPARγ/NFκB Pathway and Reduction of Signal Transducers in the AGEs/RAGE Axis Recruitment into Lipid Rafts.

Recent studies revealed that dietary intake of docosahexaenoic acid (DHA) prevented diabetic retinopathy (DR), but the underlying mechanism was not fully understood. Retinal microglia are a specialize...

Report on the creation of a diabetes register and retinopathy screening outcomes in the Mid-West of Ireland.

With concerns that blind registration in Ireland due to diabetic retinopathy is continuing to rise, a structured retinopathy screening service is in the process of being rolled out nationally.

EVOLUTION OF CONTROLLING DIABETIC RETINOPATHY: Changing Trends in the Management of Diabetic Macular Edema at a Single Institution Over the Past Decade.

To report the evolution of treatment in managing diabetic macular edema (DME) in a "real world" clinical setting.

Medication adherence and quality of life among the elderly with diabetic retinopathy.

one hundred (n=100) elderly outpatients with diabetic retinopathy taking antihypertensives and/or oral antidiabetics/insulin were interviewed. Adherence was evaluated by the adherence proportion and i...

Pigment Epithelium-Derived Factor Inhibits Retinal Microvascular Dysfunction Induced By 12/15-Lipoxygenase-Derived Eicosanoids.

We recently demonstrated that 12/15-lipoxygenase (LOX) derived metabolites, hydroxyeicosatetraenoic acids (HETEs), contribute to diabetic retinopathy (DR) via NADPH oxidase (NOX) and disruption of the...

Identifying glucose thresholds for incident diabetes by physiological analysis: a mathematical solution.

Plasma glucose thresholds for diagnosis of type 2 diabetes are currently based on outcome data (risk of retinopathy), an inherently ill-conditioned approach. A radically different approach is to consi...

Identification of Protein Network Alterations upon Retinal Ischemia-Reperfusion Injury by Quantitative Proteomics Using a Rattus norvegicus Model.

Retinal ischemia is a common feature associated with several ocular diseases, including diabetic retinopathy. In this study, we investigated the effect of a retinal ischemia and reperfusion (I/R) inju...

News Articles [130 Associated News Articles listed on BioPortfolio]

Evaluation of retinopathy of prematurity screening in reverse Kangaroo Mother Care: a pilot study

Evaluation of retinopathy of prematurity screening in reverse Kangaroo Mother Care: a pilot study Eye advance online publication, January 23 2015. doi:10.1038/eye.2014.340 Authors: T R Padh...

Welch Allyn buys maker of diabetic retinopathy tests

Welch Allyn announced it has purchased Hubble Telemedical, a Knoxville, Tenn.-based maker of remote eye tests for diabetic re -More- NEW VIDEO: How to get Brazil ANVISA regulatory approval I...

Telemedicine Imaging May Speed Diagnosis, Management of ROP

Remote access could expand screening and treatment options for retinopathy of prematurity, which threatens vision in extremely premature infants. Medscape Medical News

Stratifying risk of retinopathy in diabetes and other stories . . .

A systematic review by the OPEN Project (To Overcome failure to Publish nEgative fiNdings)—an initiative funded by the European Commission—looked at 39 studies covering more than 20 000 clinical...

Diopsys NOVA Testing System Fits Into Practice Patterns Suggested By World Glaucoma Association Consensus Series

Diopsys® NOVA ERG and VEP protocols along with tests looking at optic nerve structure can be used for evaluation of glaucoma progression Pine Brook, NJ (PRWEB) January 20, 2015 Since the month o...

Welch Allyn Acquires Hubble Telemedical to Combat Diabetic Retinopathy in Primary Care Settings

SKANEATELES FALLS, NY--(Marketwired - January 20, 2015) - Welch Allyn, Inc., a leading medical diagnostic device company that delivers practical innovation at the point of care, today announced the ac...

Wide-field imaging and OCT vs clinical evaluation of patients referred from diabetic retinopathy screening

Wide-field imaging and OCT vs clinical evaluation of patients referred from diabetic retinopathy screening Eye advance online publication, January 16 2015. doi:10.1038/eye.2014.320 Authors:...

LKC licenses Welch Allyn exclusive rights to RETeval DR diagnostic device

LKC Technologies Inc. licensed Welch Allyn Inc. exclusive worldwide rights outside of the US to its handheld RETeval DR visual electrodiagnostic device, which detects diabetic retinopathy.

CenterVue Launches EIDON at 2015 Royal Hawaiian Eye Meeting

US commercialization of world’s first true-color confocal scanner follows December 2014 FDA clearance CenterVue, Inc., a world leader in eye disease prevention using ...

ThromboGenics Appoints Dominique Vanfleteren as new Chief Financial Officer

Leuven, Belgium - 7 January, 2015 - ThromboGenics NV (Euronext Brussels: THR), an integrated biopharmaceutical company focused on developing and commercializing innovative ophthalmic med...

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Companies [6 Associated Companies listed on BioPortfolio]

Acucela Inc.

Acucela Inc. is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for treating blinding eye di...

Optos plc

Optos plc is a leading medical retinal imaging technology company. Both eye and non-eye diseases often first exhibit in the periphery of the retina. These are very difficult to de...

Promedior, Inc.

Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...

NormOxys, Inc.

NormOxys is developing a novel class of small molecule drugs, oxyrens, which enhance the body’s ability to deliver oxygen more efficiently to diseased tissues with oxygen def...

Acucela

Acucela Inc. (www.acucela.com) is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for...

Allegro Ophthalmics, LLC

With more than 100 years of combined experience in vision science and medicine, the leadership team at Allegro Ophthalmics, LLC is establishing Integrin Peptide Therapy as the ...

Clinical Trials [171 Associated Clinical Trials listed on BioPortfolio]

Dosing Study of Ranibizumab for Diabetic Retinal and Macular Edema

This study is to see whether treating diabetic retinal swelling with ranibizumab injections into the eye monthly is better than treating diabetic retinal swelling with ranibizumab injectio...

Family Myopia Study

This study will try to identify the gene or genes responsible for myopia (nearsightedness) and to examine the relationship between myopia and near work. Myopia is the most common eye disor...

Ranibizumab Treatment of Diabetic Macular Oedema With Bimonthly Monitoring After a Phase of Initial Treatment

This study evaluates a new investigational treatment regimen of three consecutive monthly doses of ranibizumab followed by an as-needed treatment regimen, with monthly follow-up for the fi...

Phenotypes of Nonproliferative Diabetic Retinopathy in DM 2 Patients Identified by OCT, CFP, RLA and mfERG (DIAMARKER)

To characterise phenotypes of Non Proliferative Diabetic Retinopathy (NPDR) progression using multimodal testing/imaging procedures.

Intravitreal Aflibercept Injection for Radiation Retinopathy

The purpose of this study is to assess the safety of intravitreal aflibercept injection - in the treatment of macular edema associated with retinopathy secondary to previous radiation ther...

Effects of Caloric Restriction in Obesity and Type 2 Diabetes

The study investigates whether a long-term 25% caloric restriction can prevent onset and/or progression of renal function deterioration, retinal involvement and cardiovascular complication...

Near Infrared Photobiomodulation Treatment for Diabetic Macular Oedema

This pilot study aims to establish that treatment with near infrared light (NIR) reduces diabetic macular oedema in patients suffering diabetic retinopathy by exerting a positive beneficia...

Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity (the STOP-ROP Multicenter Trial)

To test the efficacy, safety, and costs of providing supplemental oxygen in moderately severe retinopathy of prematurity (prethreshold ROP).

Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) - Outcome Study of Cryotherapy for Retinopathy of Prematurity

To determine the safety and efficacy of trans-scleral cryotherapy of the peripheral retina in certain low birth-weight infants with retinopathy of prematurity (ROP) for reducing blindness ...

Sorbinil Retinopathy Trial (SRT)

To evaluate the safety and efficacy of the investigational drug sorbinil, an aldose reductase inhibitor, in preventing the development of diabetic retinopathy and neuropathy in persons wit...

Medical and Biotech [MESH] Definitions

A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Degenerative changes to the RETINA due to HYPERTENSION.

A drug used to reduce hemorrhage in diabetic retinopathy.

Removal of the whole or part of the vitreous body in treating endophthalmitis, diabetic retinopathy, retinal detachment, intraocular foreign bodies, and some types of glaucoma.

Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

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