Nonproliferative retinopathy - Biotech, Pharma and Life Science Channel

18:49 EST 18th December 2014 | BioPortfolio

PubMed Articles [294 Associated PubMed Articles listed on BioPortfolio]

Increased Expression of MERTK is Associated with a Unique Form of Canine Retinopathy.

Progressive retinal degenerations are among the most common causes of blindness both in human and in dogs. Canine progressive retinal atrophy (PRA) resembles human retinitis pigmentosa (RP) and is typ...

Cost-utility Analysis of Screening for Diabetic Retinopathy in Japan: A Probabilistic Markov Modeling Study.

ABSTRACT Purpose: To evaluate the cost-effectiveness for a screening interval longer than 1 year detecting diabetic retinopathy (DR) through the estimation of incremental costs per quality-adjusted li...

Foreseeable Risks? Informed Consent for Studies within the Standard of Care.

More than 1400 babies were born prematurely in the United States every day in 2005, according to the Centers for Disease Control and Prevention, and neonatologists still weren't sure how much oxygen t...

Diabetes self-care behaviors and disease control in support group attenders and nonattenders.

The prevalence rate and mortality rate of diabetes continue to increase annually. Complications associated with poor control of diabetes include renal dialysis, amputation, heart disease, stroke, reti...

Domain I-IV of β2-glycoprotein I inhibits advanced glycation end product-induced angiogenesis by down-regulating vascular endothelial growth factor 2 signaling.

Advanced glycation end products (AGEs) are a contributing factor in the angiogenesis that is characteristic of proliferative diabetic retinopathy. However, a previous study made a promising observatio...

The 5-Year Onset and Regression of Diabetic Retinopathy in Chinese Type 2 Diabetes Patients.

To determine the rate and risk factors of diabetic retinopathy (DR) onset and regression in Chinese type 2 diabetes mellitus patients.

Stereotactic Radiotherapy for Polypoidal Choroidal Vasculopathy: A Pilot Study.

Purpose: To evaluate low-voltage X-ray stereotactic radiotherapy (SRT) delivered in conjunction with intravitreal ranibizumab for the treatment of active macular polypoidal choroidal vasculopathy (PCV...

Reliability of National Neonatal Audit Project's retinopathy of prematurity screening data.

Investigation of Variants in UCP2 in Chinese Type 2 Diabetes and Diabetic Retinopathy.

The aim of this study was to investigate variants in UCP2 genes in type 2 diabetes mellitus (DM) and diabetic retinopathy (DR) in Chinese population.

Response to: 'Reliability of National Neonatal Audit Project's retinopathy of prematurity screening data' by Finer and colleagues.

News Articles [127 Associated News Articles listed on BioPortfolio]

Ophthalmic Devices Market - Global Industry Growth, Size, Share, Trends, Analysis And Forecast To 2020 Research Report By Grand View Research, Inc.

New Market Research Report Titled "Global Ophthalmic Devices Market Analysis Size And Segment Forecasts To 2020" Has Beed Added to GrandViewReseach.com Report Database. View full report - ht...

Genentech's Lucentis dubbed 'breakthrough' in diabetic retinopathy

If approved by the FDA, Lucentis could be the first eye medicine available for diabetic retinopathy, the most common diabetic eye disease and the leading cause of new cases of blindness in working-age...

FDA breakthrough status granted to Lucentis for diabetic retinopathy

Genentech's Lucentis, or ranibizumab, secured breakthrough therapy status from the FDA as a treatment for diabetic retinopath -More- 

Top-Selling Eye Vitamins Don't Match Scientific Evidence

Provided by Dayle Kern, American Academy of Ophthalmology Research shows that, of 11 popular supplements analyzed, 7 do not adhere to proven formulas; all 11 have misleading claims With Americans sp...

Major blood vessel gene contributes to vision loss in premature infants

A gene known to play a major role in constricting blood vessels also appears to be a major player in the aberrant blood vessel growth that can destroy the vision of premature babies. Endothelin gene e...

Shire to develop mRNA technology with $15m cystic fibrosis collaboration

Shire is collaborating with Cystic Fibrosis Foundation Therapeutics (CFFT), the non-profit R&D arm of the Cystic Fibrosis Foundation, to support its Messenger RNA (mRNA) technology platform for CF...

Shire, CF Foundation in $15M discovery deal

Shire plc (LSE:SHP; NASDAQ:SHPG) partnered with the Cystic Fibrosis Foundation's drug development arm to develop mRNA replacement therapies to treat CF patients with mutations in the cystic fibrosis t...

Top-Selling Eye Vitamins Found Not to Match Scientific Evidence

SAN FRANCISCO, Dec. 9, 2014 /PRNewswire-USNewswire/ -- With Americans spending billions of dollars each year on nutritional supplements, researchers have analyzed popular eye vitamins to determin...

CenterVue EIDON Receives 510(k) FDA Clearance

The world’s first true-color confocal scanner cleared for sale in the United States CenterVue, a world leader in eye disease prevention using innovative imaging techn...

LKC Technologies Signed an Exclusive Distribution Agreement for RETeval® DR Visual Electrodiagnostic System

GAITHERSBURG, Md., Dec. 4, 2014 /PRNewswire/ -- Welch Allyn, a leading medical diagnostic device company that delivers pragmatic innovation at the point of care, and LKC Technologies, Inc., the worldw...

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Companies [6 Associated Companies listed on BioPortfolio]

Acucela Inc.

Acucela Inc. is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for treating blinding eye di...

Optos plc

Optos plc is a leading medical retinal imaging technology company. Both eye and non-eye diseases often first exhibit in the periphery of the retina. These are very difficult to de...

Promedior, Inc.

Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...

NormOxys, Inc.

NormOxys is developing a novel class of small molecule drugs, oxyrens, which enhance the body’s ability to deliver oxygen more efficiently to diseased tissues with oxygen def...

Acucela

Acucela Inc. (www.acucela.com) is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for...

Allegro Ophthalmics, LLC

With more than 100 years of combined experience in vision science and medicine, the leadership team at Allegro Ophthalmics, LLC is establishing Integrin Peptide Therapy as the ...

Clinical Trials [171 Associated Clinical Trials listed on BioPortfolio]

Dosing Study of Ranibizumab for Diabetic Retinal and Macular Edema

This study is to see whether treating diabetic retinal swelling with ranibizumab injections into the eye monthly is better than treating diabetic retinal swelling with ranibizumab injectio...

Family Myopia Study

This study will try to identify the gene or genes responsible for myopia (nearsightedness) and to examine the relationship between myopia and near work. Myopia is the most common eye disor...

Ranibizumab Treatment of Diabetic Macular Oedema With Bimonthly Monitoring After a Phase of Initial Treatment

This study evaluates a new investigational treatment regimen of three consecutive monthly doses of ranibizumab followed by an as-needed treatment regimen, with monthly follow-up for the fi...

Phenotypes of Nonproliferative Diabetic Retinopathy in DM 2 Patients Identified by OCT, CFP, RLA and mfERG (DIAMARKER)

To characterise phenotypes of Non Proliferative Diabetic Retinopathy (NPDR) progression using multimodal testing/imaging procedures.

Intravitreal Aflibercept Injection for Radiation Retinopathy

The purpose of this study is to assess the safety of intravitreal aflibercept injection - in the treatment of macular edema associated with retinopathy secondary to previous radiation ther...

Effects of Caloric Restriction in Obesity and Type 2 Diabetes

The study investigates whether a long-term 25% caloric restriction can prevent onset and/or progression of renal function deterioration, retinal involvement and cardiovascular complication...

Near Infrared Photobiomodulation Treatment for Diabetic Macular Oedema

This pilot study aims to establish that treatment with near infrared light (NIR) reduces diabetic macular oedema in patients suffering diabetic retinopathy by exerting a positive beneficia...

Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity (the STOP-ROP Multicenter Trial)

To test the efficacy, safety, and costs of providing supplemental oxygen in moderately severe retinopathy of prematurity (prethreshold ROP).

Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) - Outcome Study of Cryotherapy for Retinopathy of Prematurity

To determine the safety and efficacy of trans-scleral cryotherapy of the peripheral retina in certain low birth-weight infants with retinopathy of prematurity (ROP) for reducing blindness ...

Sorbinil Retinopathy Trial (SRT)

To evaluate the safety and efficacy of the investigational drug sorbinil, an aldose reductase inhibitor, in preventing the development of diabetic retinopathy and neuropathy in persons wit...

Medical and Biotech [MESH] Definitions

A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Degenerative changes to the RETINA due to HYPERTENSION.

A drug used to reduce hemorrhage in diabetic retinopathy.

Removal of the whole or part of the vitreous body in treating endophthalmitis, diabetic retinopathy, retinal detachment, intraocular foreign bodies, and some types of glaucoma.

Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

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