Nontyphoidal Salmonella Infections - Biotech, Pharma and Life Science Channel
PubMed Articles
Protection against Trichinella infections has been achieved using various parasite antigens and adjuvants. Recently, we reported that immunization of mice with an attenuated Salmonella strain displayi...
Trichinella infections in different host species of an endemic district of Serbia.
Trichinella infections are endemic in the Balkan region of Europe. Though trichinellosis and agents thereof are serious problems for human health and animal husbandry, only a limited number of Trichin...
Trichinella pseudospiralis infection can modulate the immunological response of autoimmune and allergic diseases leading to the amelioration of these diseases. The present study was undertaken to comp...
Unique antigenic gene expression at different developmental stages of Trichinella pseudospiralis.
Parasite-induced and parasite-regulated larval capsule formation and host immunosuppression are two major characteristics that are unique in Trichinella spp. infections, but the molecule(s) and mechan...
Survey of Trichinella infections in domestic pigs from northern and eastern Henan, China.
The aim of this work was to investigate the current situation of Trichinella infections in swine in the cities of Anyang and Shanqiu in the Henan province historically designated as trichinellosis-fre...
Thymoma and immunodeficiency: (18)F-FDG-PET/CT imaging of Good syndrome.
"Good syndrome" is defined as the combination of thymoma, hypogammaglobulinemia, low numbers of peripheral B cells and variable defects in cell-mediated immunity with a CD4 T lymphopenia and an invert...
Phage therapy presents an alternative therapeutic option in treating infections caused by methicillin-resistant Staphylococcus aureus (MRSA) strains not responding to antibiotic therapy. However, it i...
Human parvoviruses B19, PARV4 and bocavirus in pediatric patients with allogeneic hematopoietic SCT.
Among the immunocompetent, infections with parvovirus B19 (B19V) and human bocavirus (HBoV) 1 range clinically from asymptomatic to severe, while following allogeneic hematopoietic SCT (HSCT) B19V can...
National Agenda for Prevention of Healthcare-Associated Infections in Dialysis Centers.
Healthcare-associated infections (HAIs) are among the leading causes of morbidity and mortality in dialysis patients. To coordinate HAI prevention efforts, the U.S. Department of Health and Human Serv...
As of May 6, 2013, Michigan had reported 167 (52%) of the 320 paraspinal or spinal infections without meningitis associated with the 2012-2013 fungal meningitis outbreak nationally. Although the index...
News Articles
End Points in Trials of Treatments for Skin Infections
To the Editor: In accord with US Food and Drug Administration guidance for skin infection clinical trials, Dr Prokocimer and colleagues reported an early “cessation of lesion spread” analysis as t...
End Points in Trials of Treatments for Skin Infections—Reply
In Reply: Dr Spellberg raises the question of whether a cessation of lesion spread in ABSSSIs can be considered a cure of the disease. This issue was discussed by the Foundation for the National Insti...
Study examines outbreak of spinal infections in Michigan
(HealthDay)—Factors such as increased case finding may explain why Michigan had half of the total spinal infections associated with contaminated methylprednisolone acetate in the recent fungal menin...
Report by Johns Hopkins Cancer Center Suggests Neutral IV Connector is Safest
Fewer Infections and Less Clotting Associated with Neutral Fluid Displacement Connector, Says Presentation at Oncology Meeting Research on different types of IV connectors led...
Novo purchases Xellia Pharmaceuticals for US$700m
Xellia manufactures antibiotics for multi-drug resistant infections using fermentation-based processes
Michigan Hit Hard by Spine Infections From Contaminated MPA
More than half of spinal and paraspinal infections tied to contaminated methylprednisolone acetate are in Michigan, the CDC says. Medscape Medical News
Procalcitonin Tests for Identifying Bacterial Infections
How accurate are procalcitonin tests for identifying secondary bacterial infections in patients with influenza? Influenza and Other Respiratory Viruses
Carbapenem Resistance in Acinetobacter baumannii
Carbapenem resistance among Acinetobacter baumannii isolates is rapidly increasing and has been widely implicated in nosocomial infections and hospital outbreaks. Expert Review of Anti-Infective The...
Superbug not being monitored by government
A BBC investigation has found hospitals in England are not officially required to report cases of 'superbug' infections.
Synthetic Biologics to Present at the 2nd Annual Marcum LLP MicroCap Conference
ROCKVILLE, Md., May 21, 2013 /PRNewswire/ -- Synthetic Biologics, Inc. (NYSE MKT: SYN), a developer of biologics focused on the prevention and treatment of serious infectious diseases, ann...
Companies
Aradigm Corporation and Grifols S.A.
Aradigm is an emerging specialty pharmaceutical company focused on the development and commercialization of drugs delivered by inhalation for the prevention and treatment of sever...
Cell Medica is a clinical stage cellular therapeutics company engaged in the development and delivery of cellular immunotherapy treatment strategies for infectious disease and can...
Around the world, medical professionals turn to Kimberly-Clark for a wide portfolio of solutions that improve the health, hygiene and well-being of their patients and staff. As pa...
Centegen, Inc., is a development-stage company focused on novel approaches to prevent and to treat infections caused by staphylococci.
PinPointe USA, Inc., located in Chico, California, develops and markets innovative laser-based devices for the treatment of infections by healthcare providers for patients worldwi...
Arsanis is committed to the development of monoclonal antibody therapeutics against severe infectious diseases that cannot be controlled with currently available medical treatment...
Founded in 1994, IrriMax® Corporation develops and markets wound irrigation solutions using a patented, innovative delivery method that produces unmatched efficacy and safety....
Achaogen is a clinical-stage biopharmaceutical company focused on the discovery and development of antibiotics for the treatment of serious infections caused by multi-drug resista...
Colby is a privately held company based in Madison, WI and San Jose, CA. Colby is developing new oral small molecule signal transduction modulator drugs and immune modulator bioph...
Epidermolysis Bullosa (EB) is a rare genetic disorder characterized by the presence of extremely fragile skin and recurrent blister formation, resulting from minor mechanical fric...
Clinical Trials
Moxifloxacin in Pediatric Subjects With Complicated Intra-abdominal Infection
The primary focus of the study is the evaluation of the safety of treatment with moxifloxacin in a pediatric population 3 months to
Safety and Acceptability of Carraguard™ Among HIV-Negative Couples in Thailand
The primary aims of the study were to assess the safety and acceptability of Carraguard applied vaginally prior to sexual intercourse for six months in both women and men; and to examine s...
Study Evaluating Emergency-Use Tigecycline in Subjects With Resistant Pathogens.
The purpose of this study is to provide a mechanism for the emergency use of tigecycline in the appropriate clinical situations. The secondary objective is to evaluate the safety and effi...
Study of the Use of Coated Venous Catheters in the Critically Ill Child
This study should help determine to determine whether or not the use of an antibiotic coated catheter will significantly reduce the number of central line related bloodstream infections in...
Study Evaluating Vaccine in Adults With HIV
The purpose of this study is to learn whether the study vaccine and adjuvants (drugs that are used to help improve immune responses) have an acceptable safety profile in treating individua...
SCOPE: Observational Study of the Consequences of the Protease Inhibitor Era
SCOPE is an observational, prospective study of HIV-1 infected volunteers designed to provide a specimen bank of samples with carefully characterized clinical data. SCOPE specimens will b...
Organ Transplant Infection Prevention and Detection Project
Fungal infections are leading causes of morbidity and mortality in transplant recipients, yet comprehensive epidemiologic studies in this area are lacking. For this reason, the Centers for...
Limited Access Protocol of Posaconazole in Invasive Fungal Infections Study PO2095
Therapeutic options for serious fungal infections are limited by intrinsic and acquired resistance to existing antifungal agents. For example, zygomycetes (such as Mucor spp.) are intrinsi...
Patients admitted into the Intensive Care Unit (ICU) have an intravenous (IV) catheter (small plastic tube) placed in their vein. Very occasionally (4 times out of 100) the insertion of a...
The Quality of Life of Patients With Severe Illnesses
Lately researchers and clinicians have emphasized the health related quality of life. Several reasons account for this trend. First of all, the advanced medical practices have contributed...
Videos
Sir Ronald Ross Grandson opens Ronald Ross Building, Institute of Infection Global Health, Liverpool
LIVERPOOL, UK -- 9 October 2012: The grandson of Sir Ronald Ross, the 1902 Nobel Prize Winner, opened the University of Liverpool's new £90 million research ...
Medical and Biotech [MESH] Definitions
Viridans Streptococci
A large heterogeneous group of mostly alpha-hemolytic streptococci. They colonize the respiratory tract at birth and generally have a low degree of pathogenicity. This group of species includes STREPTOCOCCUS MITIS; STREPTOCOCCUS MUTANS; STREPTOCOCCUS ORALIS; STREPTOCOCCUS SANGUIS; STREPTOCOCCUS SOBRINUS; and the STREPTOCOCCUS MILLERI GROUP. The latter are often beta-hemolytic and commonly produce invasive pyogenic infections including brain and abdominal abscesses.
Streptococcus Milleri Group
A subset of VIRIDANS STREPTOCOCCI, but the species in this group differ in their hemolytic pattern and diseases caused. These species are often beta-hemolytic and produce pyogenic infections.
Factor For Inversion Stimulation Protein
A highly abundant DNA binding protein whose expression is strongly correlated with the growth phase of bacteria. The protein plays a role in regulating DNA topology and activation of RIBOSOMAL RNA transcription. It was originally identified as a factor required for inversion stimulation by the Hin recombinase of SALMONELLA and Gin site-specific recombinase of BACTERIOPHAGE MU.
Neisseria Meningitidis, Serogroup B
Strains of Neisseria meningitidis which are the most common ones causing infections or disease in infants. Serogroup B strains are isolated most frequently in sporadic cases, and are less common in outbreaks and epidemics.
Bifidobacteriales Infections
Infections with BACTERIA of the order Bifidobacteriales. This includes infections in the genera BIFIDOBACTERIUM and GARDNERELLA, in the family Bifidobacteriaceae.
