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Nuclear Medicine - Biotech, Pharma and Life Science Channel

11:24 EDT 22nd May 2017 | BioPortfolio

Nuclear medicine is a medical specialty involving the application of radioactive substances in the diagnosis and treatment of disease.

In nuclear medicine procedures, radionuclides are combined with other elements to form chemical compounds, or else combined with existing pharmaceutical compounds, to form radiopharmaceuticals. These radiopharmaceuticals, once administered to the patient, can localize to specific organs or cellular receptors.

This property of radiopharmaceuticals allows nuclear medicine the ability to image the extent of a disease process in the body, based on the cellular function and physiology, rather than relying on physical changes in the tissue anatomy. In some diseases, nuclear medicine studies can identify medical problems at an earlier stage than other diagnostic tests. 

Treatment of diseased tissue, based on metabolism or uptake or binding of a particular ligand, may also be accomplished, similar to other areas of pharmacology. However, the treatment effects of radiopharmaceuticals rely on the tissue-destructive power of short-range ionizing radiation.

In the future, nuclear medicine may provide added impetus to the field known as molecular medicine. As understanding of biological processes in the cells of living organisms expands, specific probes can be developed to allow visualization, characterization, and quantification of biologic processes at the cellular and subcellular levels.[

Source: Wikipedia

 

News Articles [56 Associated News Articles listed on BioPortfolio]

ARTMS Products Inc. Partners with Alliance Medical to Modernize, Stabilize UK Medical Isotope Supply Chain

ARTMS Products, Inc., a Vancouver-based medical technology company, is pleased to announce that it has entered into a strategic partnership with Alliance Medical to enable and dem...

Sofie Biosciences To Acquire Zevacor Pharma

CULVER CITY, Calif., May 11, 2017 /PRNewswire/ -- Sofie Biosciences, Inc., announced today that it has entered into a definitive agreement under which it will purchase Zevacor Pharma (previously IBA M...

Ochsner Health System Adopts Endomag's Magseed® as Standard of Care for Localisation of Impalpable Breast Lesions

Magseed technology guides surgeons during a breast lumpectomy to simplify treatment and improve patient experience Endomag, the cancer healthcare company, announced today that...

Lantheus Holdings, Inc. Announces Public Secondary Offering by Selling Stockholders of 3,000,000 Shares of Common Stock

Lantheus Holdings, Inc. (“Lantheus” or the “Company”) (NASDAQ:LNTH), today announced an agreement to sell 3,000,000 shares of its common stock to be offered by certain of ...

U.S. Molecular Imaging Companies Leverage Technology Innovation and Design Modularity to Widen the Market Scope

SANTA CLARA, Calif., May 2, 2017 /PRNewswire/ -- The adoption of value-based reimbursement in the United States (U.S.) healthcare will make molecular imaging instrumental for quicker diagnosis, more a...

Radiation oncologists call on Congress to boost cancer research funding and protect patients in health care reform

WASHINGTON, May 1, 2017 /PRNewswire-USNewswire/ -- More than 100 radiation oncologists from across the United States are on Capitol Hill urging Congress to grow its investment in cancer research ...

Faxitron Announces LOCalizer™ Radiofrequency Identification System Granted FDA 510(k) Clearance for Use in Breast Lesion Localization

Innovative technology enables precision and ease of use with a wireless Tag and Reader system that is free of radioactivity Faxitron, a 50-year leader in advancing technology ...

Lantheus and GE Healthcare Announce the Signing of a Definitive License Agreement for Worldwide Development and Commercialization of Flurpiridaz F 18

Companies also announce the extension and expansion of their existing commercial supply agreement for nuclear products through 2020 Lantheus Holdings, Inc. (NASDAQ: LNT...

1 in 6 African American Men Will Get Prostate Cancer

BENICIA, Calif., April 20, 2017 /PRNewswire/ -- According to You Are Enough Now, 1 in 6 black men will develop prostate cancer. Close to 30,000 men die from the disease every year. It is the four...

UC Davis Comprehensive Cancer Center Adopts Samsung BodyTom® for Brachytherapy Suite

Samsung NeuroLogica, an emerging leader in medical imaging technology, announced today that the UC Davis Comprehensive Cancer Center in Sacramento, Ca., added BodyTom®, the world...

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Companies [9 Associated Companies listed on BioPortfolio]

Navidea Biopharmaceuticals

Navidea Biopharmaceuticals (NYSE Amex: NAVB) is a biopharmaceutical company focused on the development and commercialization of precision diagnostics and radiopharmaceutical agent...

Advanced Medical Isotope Corporation

Advanced Medical Isotope Corporation (ADMD) is a late stage development company engaged in the development of brachytherapy devices for therapeutic applications. AMIC's focus is o...

Lantheus Holdings, Inc.

Lantheus Holdings, Inc. is the parent company of Lantheus Medical Imaging, Inc. (“LMI”), which is a global leader in developing, manufacturing, selling and distributing ...

Cambridge Isotope Laboratories, Inc.

Cambridge Isotope Laboratories, Inc. (www.isotope.com) is the world's premier supplier of stable isotopes and stable isotope labeled compounds for research applications in structu...

Navidea Biopharmaceuticals Inc.

Navidea Biopharmaceuticals, Inc. (NYSE MKT: NAVB) is a biopharmaceutical company focused on the development and commercialization of precision diagnostics and radiopharmaceutical ...

Navidea Biopharmaceuticals, Inc.

Navidea Biopharmaceuticals, Inc. (NYSE Amex: NAVB) is a biopharmaceutical company focused on the development and commercialization of precision diagnostics and radiopharmaceutical...

Neoprobe Corporation and Navidea Biopharmaceuticals, Inc.

Navidea Biopharmaceuticals (NYSE Amex: NAVB) is a biopharmaceutical company focused on the development and commercialization of precision diagnostics and radiopharmaceutical agent...

KineMed, Inc.

KineMed, Inc. ("KineMed" or the "Company") is a drug discovery and development company employing its proprietary translational medicine technology (AquaTag™ and KineMarkerâ...

Symbiotic Research Services

SR is a contract research organization (CRO) which is licensed to conduct research with radio labeled C-14 materials. SR has been inspected by the US-EPA and the NJ-DEP Division o...

Clinical Trials [343 Associated Clinical Trials listed on BioPortfolio]

Innovative Planning and Guidance System for Prostate Focal Brachytherapy

A key feature of low-dose brachytherapy is that irradiation affects only a local area around the inserted radiation sources. The exposure of healthy tissues around these sources is then re...

Detection of Clinically Significant Prostate Cancer With 18F-DCFPyL PET/MR

Background: Currently, patients suspected of having prostate cancer undergo ultrasound-guided systematic biopsies of the prostate. However, up to a quarter of clinically significant tumor...

Assessment of the Biodistribution and Safety of [18F]MNI-968 in Healthy Subjects

The overall goal of this protocol is to evaluate the biodistribution of [18F]MNI-968 as a D1 receptor targeted radiopharmaceutical.

211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

This phase I/II clinical trial studies the side effects and best dose of 211^astatine(At)-BC8-B10 before donor stem cell transplant in treating patients with high-risk acute myeloid leukem...

PET/MRI Evaluation of Cardiac Amyloid

Cardiac amyloidosis is a disorder characterized by the deposition of abnormal proteins called amyloid in the heart tissue. This makes it difficult for the heart to function properly. The i...

Exercise Physiology Study

People with type 1 diabetes often find exercise very difficult to manage, because of the high risk for low blood glucose levels. This can occur very quickly once exercise starts and presen...

Intraoperative Brachytherapy for Central Nervous System Lesions: A Validation Study of a Radioactive Seed Loading Device

The researchers recognized the possible clinical usefulness of a shielded device or jig to help increase the accuracy but decrease the time of loading the seeds into the biocompatible mate...

Phase 0 Study of [18F]MNI-968 as a Marker for D1 Receptor in Healthy Subjects

The overall goal of this protocol is to evaluate [18F]MNI-968 (aka PF-06730110) as a D1 receptor targeted radiopharmaceutical.

Phase 1 Test-retest Evaluation of [18F]MK-6240 PET as an Imaging Marker for Neurofibrillary Tangles in the Brain

The overall goal of this protocol is to evaluate [18F]MK-6240 (also known as [18F]MNI-946) a tau targeted radiopharmaceutical.

Total Thyroidectomy Versus Thionamides in Patients With Moderate-to-Severe Graves' Ophthalmopathy

Introduction: Graves disease (GD) is characterized by thyrotoxicosis and goiter, arising through circulating autoantibodies that bind to and stimulate the thyroid hormone receptor (TSHR). ...

PubMed Articles [234 Associated PubMed Articles listed on BioPortfolio]

Accuracy of (177)Lu activity quantification in SPECT imaging: a phantom study.

The aim of the study is to assess accuracy of activity quantification of (177)Lu studies performed according to recommendations provided by the committee on Medical Internal Radiation Dose (MIRD) pamp...

Label-free and sensitive assay for deoxyribonuclease I activity based on enzymatically-polymerized superlong poly(thymine)-hosted fluorescent copper nanoparticles.

Deoxyribonuclease I (DNase I) is an important physiological indicator and diagnostic biomarker, but traditional methods for assessing its activity are time-consuming, laborious, and usually radioactiv...

Comparison of Homogeneous and Particulate Lung Dose Rates For Small Mammals.

Small, highly radioactive fragments of material incorporated into metallic matrices are commonly found at nuclear weapons test and accident sites and can be inhaled by wildlife. Inhaled particles ofte...

Data-driven event-by-event respiratory motion correction using TOF PET list-mode centroid of distribution.

Data-driven respiratory gating techniques were developed to correct for respiratory motion in PET studies, without the help of external motion tracking systems. Due to the greatly increased image nois...

Gamma irradiation of resting eggs of Moina macrocopa affects individual and population performance of hatchlings.

We investigated the effects of γ-radiation on the survival of resting eggs of the cladoceran Moina macrocopa, on the parameters of the life cycle of neonates hatched from the irradiated eggs and on t...

Endogenous synthesis of milk oleic acid in dairy ewes: In vivo measurement using (13)C-labeled stearic acid.

The use of stable isotopes is a reliable and risk-free alternative to radioactive tracers for directly examining in vivo fatty acid (FA) metabolism. However, very limited information is available in r...

Measuring and assessing individual external doses during the rehabilitation phase in Iitate village after the Fukushima Daiichi nuclear power plant accident.

After the Fukushima Daiichi Nuclear Power Plant accident in 2011, Iitate village was placed under an evacuation order because the level of radioactive materials drifting from the nuclear plant to the ...

Anti-thyroglobulin antibodies do not significantly increase the risk of finding iodine avid metastases on post-radioactive iodine ablation scan in low-risk thyroid cancer patients.

Post-operative thyroglobulin (Tg) levels can predict the likelihood of residual cancer, including distant metastases, thereby influencing postsurgical treatment strategies even in patients with low-ri...

Pectin Esterification Degree in the Bioavailability of Non-heme Iron in Women.

Pectins are a type of soluble fiber present in natural and processed foods. Evidence regarding the effect of esterification degree of pectins on iron absorption in humans is scarce. In the present stu...

How does radioactive iodine affect the nose?

To determine the effect of radioactive iodine (RAI) treatment on the nasal mucosa and nasal functions.

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Medical and Biotech [MESH] Definitions

Radioactive substances which act as pollutants. They include chemicals whose radiation is released via radioactive waste, nuclear accidents, fallout from nuclear explosions, and the like.

Uncontrolled release of radioactive material from its containment. This either threatens to, or does, cause exposure to a radioactive hazard. Such an incident may occur accidentally or deliberately.

Contamination of air with radioactive substances.

Liquid, solid, or gaseous waste resulting from mining of radioactive ore, production of reactor fuel materials, reactor operation, processing of irradiated reactor fuels, and related operations, and from use of radioactive materials in research, industry, and medicine. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

A nontoxic radiopharmaceutical that is used in the diagnostic imaging of the renal cortex.

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