Obesity - Biotech, Pharma and Life Science Channel
Obesity is the condition in which excess fat has accumulated in the body (mostly in subcutaneous tissues). clinical obesity is considered to be present when a person has a BMI of over 30 (Oxford Dictionary of Medicine). It is becoming increasing common in western societies. Although predominantly caused by over-eating, there may be a genetic aspect too. Obesity is a risk factor for a number of diseases including arthritis, heart disease and depression. It is a major area of research because it is so endemic and possible complications, which cost millions each year.
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PubMed Articles
Stress incontinence in elderly women.
Stress incontinence is one of the major challenges in geriatric medicine. This is becoming more apparent in routine urology practice with the demographic changes in the population. A thorough diagnosi...
The rise in childhood obesity has lead to an increased number of children with lipid abnormalities and the predominance of a combined dyslipidemic pattern characterized by a moderate-to-severe elevati...
The Sympathetic Nervous System in Obesity Hypertension.
Abundant evidence supports a role of the sympathetic nervous system in the pathogenesis of obesity-related hypertension. However, the nature and temporal progression of mechanisms underlying this symp...
The unrelenting fall of the pharmacological treatment of obesity.
Nowadays pharmacological therapy to limit obesity has reached a critical stage: not only have Authorities limited the use of antiobesity drugs due to their proven inefficacy and dangerous side effects...
Background: Among patients with coronary artery disease (CAD), high-density lipoprotein cholesterol (HDL-C) is a cardiac protective factor. In contrast, body mass index (BMI) is inversely related to...
The impact of obesity on cardiac dysfunction in patients with sleep-disordered breathing.
INTRODUCTION: Obesity and heart failure are strongly associated with sleep-disordered breathing (SDB). However, the determinants of cardiac dysfunction in patients with SDB are not known. METHODS: We...
Depression is the most common psychiatric disorder worldwide. The burden of disease for depression goes beyond functioning and quality of life and extends to somatic health. Depression has been shown...
Recent advances have demonstrated that the adipose tissue plays a central role in regulating overall energy balance. Obesity results from a chronic deregulation of energy balance, with energy intake e...
Complication Rates After Hip or Knee Arthroplasty in Morbidly Obese Patients.
BACKGROUND: Morbid obesity has been shown to be a risk factor for increased complications after THA and TKA; however, large studies that would determine the effect size are lacking. QUESTIONS/PURPOSES...
Recent genome-wide association studies have identified multiple loci associated with BMI or the waist:hip ratio (WHR). However, evidence on gene-lifestyle interactions is still scarce, and investigati...
News Articles
By Spencer Osborne: With sales of anti-obesity drug Qsymia not progressing to the desired point, and cash burn at Vivus (VVUS) such that it was faced with either added debt, stock dilution through an...
A Vicious Cycle That Helps Obesity Perpetuate Itself
With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds su...
UnitedHealthcare IRONKIDS Florida Energizes Youth About Healthy Living Through “IRONMAN” Races
The UnitedHealthcare IRONKIDS Florida event raced around Lake Eva Park today. Thomas Moore from UnitedHealthcare of Florida, and Patrick McGee, IRONKIDS Race Director kicked-off t...
The National Cancer Institute reports that obese people are twice as likely to develop esophageal cancer. Diet Doc's newly improved and modernized version of hCG diet plans makes losing weight saf...
Mobile, AL (PRWEB) May 18, 2013 Although obesity is associated with an increased risk for several malignant tumors, the association between obesity and esophageal adenocarcinoma, a type of esophage...
Statins May Reduce Exercise Benefits For Obese Adults
Statins, the most widely prescribed drugs worldwide, are often suggested to lower cholesterol and prevent heart disease in individuals with obesity, diabetes and metabolic syndrome, which is a combina...
Active videogaming (‘exergaming’) recommended to improve children’s health
Levels of physical inactivity and obesity are very high in children, with fewer than 50% of primary school-aged boys and fewer than 28% of girls meeting the minimum levels of physical activity...
Diet Doc offers prescription hCG diet plans that signal the body to release and burn years of trapped fat, resulting in fast weight loss, better health, and the reduction of risk for weight-related li...
Weight Loss/Obesity Management Market to Reach $361 Billion By 2017 - New Report by MarketandMarkets
(PRWEB) May 17, 2013 The Weight Loss/Obesity Management Market â [Meal Replacements, Slimming Centers, Nutrition & Psychological Consultancy, Treadmill, Ellipticals, Strength Training, Gas...
Anti-Appetite Hormone In Brain Affected Negatively By Obesity
Michael Harper for redOrbit.com – Your Universe Online Obesity has been found to alter the body in more ways than one. Previous studies have shown that adding too much mass to a body can chemically...
Events
Diabetes: Secondary Complications, Regulation and Innovation Conference
SMi is very proud to present our 11th conference focusing on Diabetes and metabolic disorders taking place on 1st and 2nd Oct 2013, London.
Companies
Physician Therapeutics is a division of Targeted Medical Pharma, Inc., a specialty pharmaceutical company that develops and sells prescription medical foods to physi...
TheAmerican Association of Clinical Endocrinologists (AACE)
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
Health Foundation of South Florida
WHO: USDA Regional Administrator Don Arnette; City of Miami Commissioner Wifredo Gort; Florida Department of Children & Families Secretary George Sheldon, (increasing access of SN...
WHAT:The USDA Dietary Guidelines for 2010 perpetuate the mistakes of previous guidelines, continuing to promote a diet low in fat and high in processed grain and cereal products,...
Nimbus Discovery is applying advances in computer-based drug discovery to develop new medicines against important drug targets and thereby unlock fundamental biological pathways....
Sizewise, a privately held company, manufactures medical equipment ranging from hospital bed frames and specialized mattresses to wheelchairs and other devices that assist in the...
The Aetna Foundation, Inc. is the independent charitable and philanthropic arm of Aetna Inc. Since 1980, Aetna and the Aetna Foundation have contributed $394 million in grants and...
IDEAL LIFE, the industry leader in remote health management solutions, has created an innovative platform that addresses many of todayâs most challenging and costly healthcar...
CoolJuice® Beverage Company (www.CoolJuice.com) was founded in 2006 to help tackle the child obesity epidemic in the U.S.A. CoolJuice produces all natural, 100% juiceblends...
Founded by the Dizzy Feet Foundation and the Larry King Cardiac Foundation, with the assistance of CRT/tanaka, in 2011, Dance 4 Your Life! is a national initiative to promo...
Clinical Trials
Body Heat Content and Dissipation in Obese and Normal Weight Adults
This study will investigate how different parts of the body lose body heat and will measure the heat released by specific areas such as the limbs and abdomen. Animal studies suggest that d...
Evaluation of Pulse Fibre Supplementation on Obesity and the Metabolic Syndrome
The recent dramatic increase in obesity has been linked to a reduction of dietary fibre intake. We hypothesized that supplementing the diet of overweight and obesity adults with pulse fibr...
New Media Obesity Treatment in Community Health Centers
This purpose of this trial is to determine whether a 12-month eHealth behavioral intervention that includes interactive self-monitoring and feedback, tailored skills training materials, te...
Mediators of Abnormal Reproductive Function in Obesity (MARO)
The study is seeking to understand how being overweight and obese makes women less fertile. The studies the investigators have done so far indicate that there is a hormone or other substan...
Janssen - Glucose Regulation/Risp/Olanz
Abnormalities in peripheral glucose regulation and type 2 diabetes can occur more commonly in individuals with schizophrenia than in healthy subjects or in other psychiatric conditions. A...
Oral Contraceptives in the Metabolic Syndrome
Oral contraceptives (OCs) are the most widely used method of reversible birth control. However, the long-term cardiovascular safety of the widely used low-dose OCs (ethinyl-estradiol < 50...
Modifying Obesogenic Homes: Impact on Weight Maintenance
The obesity epidemic observed in recent years can be largely attributed to an obesogenic environment that encourages overeating and sedentary lifestyles. Behavioral weight control treatmen...
Dietary Compensation With Substitution of Meat Products With White Button Mushrooms.
Unfortunately, current methods of achieving weight control are disappointing. There is also a great deal of public confusion over what constitutes an appropriate diet for weight control;...
Levofloxacin Pharmacokinetics (PK) in the Severely Obese
Obesity is known to affect the concentrations of certain medications in the body. Levofloxacin is a commonly used antibiotic. Based on what the investigators know about levofloxacin and ho...
Childhood Obesity: Variations in Management
Childhood obesity has been described as a growing national epidemic. Between 1980 and 1994 the prevalence of childhood obesity doubled with 10% to 15% of children and adolescents being obe...
Videos
Top Ten Obesity Causing Foods! Worst Fattening Foods NOT to Eat | Weight Loss, Healthy Diet Tips
Top Ten Obesity Causing Foods! Worst Fattening Food NOT to Eat | Weight Loss, Healthy Diet Tips Corrina counts down the 10 worst foods you could eat in terms...
Medical and Biotech [MESH] Definitions
Overnutrition
An imbalanced nutritional status resulted from excessive intake of nutrients. Generally, overnutrition generates an energy imbalance between food consumption and energy expenditure leading to disorders such as OBESITY.
Bariatrics
Activities related to WEIGHT REDUCTION in patients with OBESITY. Treatment methods include DIET; EXERCISE; BEHAVIOR MODIFICATION; medications; and BARIATRIC SURGERY.
Bariatric Surgery
Surgical procedures aimed at producing major WEIGHT REDUCTION in patients with MORBID OBESITY.
Intra-abdominal Fat
Fatty tissue inside the ABDOMINAL CAVITY, including visceral fat and retroperitoneal fat. It is the most metabolically active fat in the body and easily accessible for LIPOLYSIS. Increased visceral fat is associated with metabolic complications of OBESITY.
Adiponectin
A 30-kDa COMPLEMENT C1Q-related protein, the most abundant gene product secreted by FAT CELLS of the white ADIPOSE TISSUE. Adiponectin modulates several physiological processes, such as metabolism of GLUCOSE and FATTY ACIDS, and immune responses. Decreased plasma adiponectin levels are associated with INSULIN RESISTANCE; TYPE 2 DIABETES MELLITUS; OBESITY; and ATHEROSCLEROSIS.
