Orphan Diseases - Biotech, Pharma and Life Science Channel
The European Organization for Rare Diseases considers orphan diseases to be those that are rare (occur in 1 in 1500 to 1 in 2500 patients, according to US Rare Disease Act 2002 and European Commission on Public Health) and neglected (due the low financial return on the development of the drug in sales). Orphaned drugs are those designed for orphaned diseases, and because of the unfavourable economic nature of developing such a drug, they are often protected by public policy.
The most prominent orphaned diseases are Huntington’s disease, acute myeloid leukaemia (AML), Hodgkin’s lymphoma, multiple myeloma, ovarian cancer and pancreatic cancer.
News Articles
CardioKinetix Announces Successful Parachute Live Case Transmission at 2013 EuroPCR Conference
CardioKinetix Inc., a medical device company pioneering a catheter-based treatment for heart failure, today announced the transmission of a live satellite feed of a clinical case...
Integrated Care Now Possible in Workers’ Compensation for Breakthrough Results
Don Duford, One Call Care Management, Presents New Vision for Improved Outcomes at Lower Cost at NCSI Annual Conference The workers’ compensation industry can achieve breakt...
Condom Nation’s First Stop in Washington, D.C.!
The Condom Nation Big Rig Tour has embarked on the second annual U.S. Condom Nation tour with a goal of distributing more than 50 million condoms in the U.S. – In 2012, the tour...
Cigna Wins a Best Employer for Healthy Lifestyles® Award from National Business Group on Health
Platinum award, highest honor Fifth year in a row for Cigna The National Business Group on Health, a non-profit association of large U.S....
Thomson Reuters Quarterly Report on U.S. Generic Drug Industry
24th May 2013: Thomson Reuters Movers and Shakers quarterly report, focusing on the U.S. generic drug industry. Movers and Shakers is the best source of information on generic approvals and...
Pfizer Inc: Re-entry to the OTC healthcare market
MarketLine have recently launched a new report - "Pfizer Inc: Re-entry to the OTC healthcare market" Introduction Pfizer, Inc. was originally founded as fine chemicals business. Follow...
Results Set a High Standard in Sustained Long Term Clinical Outcomes Elixir Medical Corporation, a developer of products that combine state-of-the-art medical devices with adv...
Covidien plc (NYSE: COV), a leading global provider of healthcare products, today announced that its board of directors has approved the separation of the Pharmaceuticals b...
Antares Pharma to Present at the Deutsche Bank Securities, Inc. 38th Annual Health Care Conference
Antares Pharma, Inc. (NASDAQ: ATRS) today announced that Paul K. Wotton, Ph.D., President and Chief Executive Officer, will present at the Deutsche Bank Securities, Inc. 38th Annu...
Reputation Impression Announces Sponsorship for Susan G. Komen for the Cure, San Diego
Reputation Impression, a Reputation Management and Marketing Company, is excited to announce its Silver Level Sponsorship for the Susan G. Komen, San Diego Race for the Cure. On S...
Events
The European Society for Translational Medicine (EUSTM) and the Centre de Recherche Public – Santé (CRP-Santé)
The Economist Events - Healthy Europe Summit June 20th 2013
From sick care to health care
Geriatric Safe Medicines Summit
Join SMi as we look to address these issues with new and innovative thinking and approaches that are being applied to geriatric clinical studies.
Evolving Big Data Management to Advance Data Analytics, Business Forecasting, and Expedite Decisions
Payer Strategies for Emerging Markets
Understand payer needs, build robust partnerships and drive profit growth.
Strategic Pipeline Planning & Portfolio Valuation
R&D Target Selection, Licensing and M&A, Prioritization and Investment Decision-Making
Cancer Vaccines will provide attendees with a complete view of the cancer immunotherapy field. Focusing on the discovery of new vaccines, developments in target identification
Diabetes: Secondary Complications, Regulation and Innovation Conference
SMi is very proud to present our 11th conference focusing on Diabetes and metabolic disorders taking place on 1st and 2nd Oct 2013, London.
The 12th annual Evolution Summit is a premium forum bringing together leaders in biopharmaceutical clinical operations with the most renowned CROs and solution providers.
BIOASIA - THE ULTIMATE 3-DAY KNOWLEDGE EXCHANGE AND NETWORKING PLATFORM FOR BUSINESS LEADERS OF LIFESCIENCES!
Companies
Astellas Pharma Inc., located in Tokyo, Japan, is a pharmaceutical company dedicated to improving the health of people around the world through the provision of innovative and reliable pharmaceuticals...
BioInvent International is a unique company dedicated to working with clients to ensure their success in the discovery, development and manufacture of antibody drugs. The discovery of new drug targets...
Globus Medical, Inc. is a leading musculoskeletal implant company based in Audubon, PA. The company was founded in 2003 by an experienced team of professionals with a shared visio...
Balfour Beatty | McCarthy is a joint venture of Balfour Beatty Construction and McCarthy Building Companies, Inc. formed to provide design-build services for the Fort Hood Replace...
DOLE is the top-selling banana in America and the world â in both conventional and organic product categories. From its founding by James Drummond Dole, the company has built...
RTI Biologics Inc. was formed when Regeneration Technologies Inc. and Tutogen Medical Inc. merged on Feb. 27, 2008. The company is now a leading provider of sterile biologi...
Herbalife Ltd. (NYSE: HLF) is a global network marketing company that sells weight-management, nutrition, and personal care products intended to support a healthy lifestyle...
John Muir Health is a not-for-profit organization that includes two of the largest medical centers in Contra Costa County: John Muir Medical Center - Walnut Creek Campus, a 330-be...
Clinical Trials
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Sarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and combining chemotherapy with periphe...
Pamidronate to Treat Osteogenesis Imperfecta in Children
This study will evaluate the effect of pamidronate-a drug that decreases bone resorption (breakdown)-on osteogenesis imperfecta. This is a genetic disorder of collagen, the major protein...
Immune Response to Hepatitis C Virus
This study will identify and characterize immune factors involved in hepatitis C infection and elimination of the virus. Individual responses to hepatitis C infection vary; some people ar...
Effects of Exenatide and Insulin Glargine in Subjects With Type 2 Diabetes
This Phase 3, open-label, multicenter study is designed to compare the effects of exenatide and insulin glargine (Lantus® injection) on beta-cell function in patients with type 2 diabetes...
Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants
To determine whether or not inhaled nitric oxide (iNO) safely decreases the incidence of chronic lung disease (CLD) in premature infants.
Cell Lines From High-Risk Breast Tissue
Background: - Many risk factors for breast cancer have been identified, including family history, endocrine background, changes in breast tissue, cancer in one breast, radiation...
Positron Emission Tomography (PET) to Study Brain Signaling
This study uses positron emission tomography (PET) to examine brain function and signaling involving phospholipids, and to see how signaling is related to blood flow. Much of the brain is...
Screening Evaluation for Women With Postpartum Depression
This study evaluates the relationship between mood changes and hormones in women with postpartum depression (PPD). This is an observational study; volunteers who participate will not rece...
Pelvic Pain in Women With Endometriosis
This study will examine pelvic pain associated with endometriosis and explore better approaches to treatment. In women with endometriosis, uterine tissue grows outside the uterus. Standa...
Imiquimod Cream in Treating Patients With Basal Cell Skin Cancer
RATIONALE: Biological therapies, such as imiquimod cream, work in different ways to stimulate the immune system and stop tumor cells from growing. PURPOSE: This randomized phase I trial i...
PubMed Articles
Incidence of hip fractures in Germany, 1995-2010.
We analyzed hip fracture incidence trends in Germany in 1995-2010, using national hospital discharge register. Overall, after age-sex-region adjustment, there was no significant trend. However, strati...
Incidence of hip fracture in Rohtak district, North India.
Hip fracture incidence is not known in India. This retrospective study was conducted to evaluate hip fracture incidence rates in Rohtak, a single district of North India. A total of 304 patients from...
Intrapartum sacral stress fracture due to pregnancy-related osteoporosis: a case report.
Low back pain (LBP) and hip pain frequently occur during pregnancy and postpartum period. Although pelvic and mechanic lesions of the soft tissues are most responsible for the etiology, sacral fractur...
INTRODUCTION: Nonunion of femoral neck fractures frequently occurs in elderly patients. In patients with rheumatoid arthritis, reoperation rates after internal fixation of a displaced femoral neck fra...
This retrospective analysis of hip fracture patients with and without muscle atrophy/weakness (MAW) revealed that those with MAW had significantly higher healthcare utilization and costs compared with...
A health economic analysis of osteoporotic fractures: who carries the burden?
This is a cost-of-illness study of osteoporotic fractures in Denmark estimating the incremental societal cost associated with osteoporotic fractures, with both direct cost and productivity cost. This...
Major aims of the 5th Central and Eastern Europe (CEE) Summit on Osteoporosis held in Bratislava, Slovakia, on 2 and 3 December 2011, were to provide participants with state-of-the-art knowledge in th...
Ski-interacting protein (SKIP) is a transcriptional cofactor distinct from other cofactors and involved in the regulation of many cancer-related proteins. This study investigated the expression of SKI...
Expression of synuclein gamma indicates poor prognosis of triple-negative breast cancer.
Synuclein gamma (SNCG), previously identified as breast cancer-specific gene 1, is highly expressed in malignant cells but not in normal epithelium. Studies have demonstrated that the expression of SN...
The aim of this study was to interrogate whether blood-borne inflammatory and nutritional markers predict long-term survival and response to neoadjuvant chemotherapy in radically treated oesophagogast...
Videos
P!nk - Just Give Me A Reason ft. Nate Ruess
From the Grammy Nominated album The Truth About Love available now - http://smarturl.it/tal Music video by P!nk featuring Nate Ruess performing Just Give Me ...
Medical and Biotech [MESH] Definitions
Physalis
A plant genus of the family SOLANACEAE. Members contain physalin and withangulatin.
Solanum
A plant genus of the family SOLANACEAE. Members contain SOLANACEOUS ALKALOIDS. Some species in this genus are called deadly nightshade which is also a common name for ATROPA BELLADONNA.
Solanum Melongena
A plant species of the genus SOLANUM, family SOLANACEAE. The fruit is a large, egg-shaped berry, varying in color from dark purple to red, yellowish, or white. The leaves are large and ovate. The flowers are pendant, violet, and two inches across.
Solanum Nigrum
A plant species of the genus SOLANUM, family SOLANACEAE that contains steroidal glycosides.
Withania
A plant genus of the family SOLANACEAE. Members contain withanolides. Withania somnifera is the source of ashwagandha and aswal.
