Osteoarthritis OA - Biotech, Pharma and Life Science Channel
PubMed Articles
Evidence-based hydro- and balneotherapy in Hungary-a systematic review and meta-analysis.
Balneotherapy is appreciated as a traditional treatment modality in medicine. Hungary is rich in thermal mineral waters. Balneotherapy has been in extensive use for centuries and its effects have been...
Assessments of serum 25-hydroxyvitamin D levels in 1,683 Japanese from a population-based cohort revealed prevalences of vitamin D insufficiency and deficiency were 81.3 and 1.2 %, respectively. Vita...
The purpose of this study was to identify differences in knee proprioceptive accuracy between subjects with early knee osteoarthritis (OA), established knee OA, and healthy controls. Furthermore, the...
Serum EGF and NGF levels of patients with brain injury and limb fracture.
To explore the expression and significance of human epidermal growth factor (EGF) and nerve growth factor (NGF) in patients with knee osteoarthritis.
Expression of NF-κB and osteopontin of synovial fluid of patients with knee osteoarthritis.
To explore the significance of osteopontin and nuclear factorκB (NF-κB) expression in patients with knee osteoarthritis.
Intraarticular Fibrinogen Does Not Reduce Blood Loss in TKA: A Randomized Clinical Trial.
BACKGROUND: Bleeding remains an ongoing concern after total knee arthroplasty (TKA). Intraarticular application of human fibrinogen with a topical thrombin has been described to stop diffuse bleeding...
The exact relationship between osteoporosis and osteoarthritis is still a matter for debate for many. The ovariectomised ewe is frequently used as a model for osteoporosis, resulting in significant al...
Surgery versus physical therapy for a meniscal tear and osteoarthritis.
Whether arthroscopic partial meniscectomy for symptomatic patients with a meniscal tear and knee osteoarthritis results in better functional outcomes than nonoperative therapy is uncertain.
News Articles
PALO ALTO, Calif. , May 17, 2013 /- Cellular Biomedicine Group (OTCQB: CBMG) today announced that it has achieved 50% enrollment of the total projected enrollment required for its Phase I trial...
U.S. Physical Therapy to Present at the 2013 UBS Global Healthcare Conference
U.S. Physical Therapy, Inc. (NYSE: USPH), a national operator of physical and occupational therapy outpatient clinics (the “Company”), today announced that its Chief Financial...
Arthritis is the nation’s leading cause of disability, affecting 50 million people, and one in five adults. Ethical Alternative Products is making available trial samples of OmniFlex and Tendonex t...
Memphis, TN (PRWEB) May 15, 2013 Chances of suffering back pain is almost unavoidable for those that are overweight or obese with SpineUniverse reporting that carrying extra pounds significantly...
Personalized Medicine for Osteoarthritis
This review reports on the important developments in personalized medicine for the diagnosis and management of osteoarthritis. Therapeutic Advances in Musculoskeletal Disease
Ferring Pharmaceuticals Inc. Adopts Local Morristown Playground
PARSIPPANY, N.J., May 14, 2013 /PRNewswire-USNewswire/ -- Ferring Pharmaceuticals Inc. has adopted the Jersey Avenue Playground as part of Morristown's "Adopt-a-Spot" program. To kick off the program,...
Study finds genetic risk factor for knee osteoarthritis
(Medical Xpress)—A newly published paper reports that individuals with radiographic knee osteoarthritis (OA) who had a specific pattern of gene variations in the interleukin-1 receptor antagonist ge...
Project Assesses Quantitative MRI in the Prognosis and Treatment of Osteoarthritis
A new project’s goal is to assess multiple imaging and biochemical biomarkers to try to find more comprehensive ways...
Unigene and Nordic Bioscience amend JDV accord; Amgen Vectibix China deal
USA-based Unigene Laboratories (PINK: UGNE) has entered into an equity transfer and exclusive license agreement with Nordic Bioscience, involving three proprietary metabolic peptide analogs for type 2...
Natural Fibres Biologically Effective For Use In Stem Cell Cartilage Repair
Over 20 million people in Europe suffer from osteoarthritis which can lead to extensive damage to the knee and hip cartilage. Stem cells offer a promising way forward but a key challenge has been to d...
Events
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Companies
Founded in 1990, U.S. Physical Therapy, Inc. (NASDAQ:USPH) operates 369 clinics in 43 states. The Company's clinics provide preventative and post-operative care for a variety of o...
Ivivi Health Sciences is an emerging leader in the field of inductive electrotherapy. Its lead product, the Ivivi Torino II, has a demonstrated mechanism of action and proven clin...
Founded in 1990, U.S. Physical Therapy, Inc. operates 418 clinics in 42 states. The Company's clinics provide preventative and post-operative care for a variety of orthopedic-rela...
Bioventus is a global leader of active orthopaedic healing, providing clinically proven and cost-effective therapies and diagnostics that help patients regain active lifestyles. T...
CD Diagnostics (www.cddiagnostics.com) is developing a series of immunoassays to detect the cause of joint pain using joint fluid analysis. The assays use a small sample of a pati...
Moximed® Inc is dedicated to improving the standard of care for patients with osteoarthritis. OA, the most common form of arthritis, leads to a breakdown of the jointâs ca...
Based in Alpharetta, Ga., Carticept Medical, Inc. is a privately held medical device company established in 2005 to develop innovative solutions for patients with osteoarthritis o...
Afferent Pharmaceuticals is focused on developing first-in-class medicines to treat chronic pain by targeting P2X3 receptors in nerve fibers. Research shows that P2X3-containin...
TiGenix NV (NYSE Euronext: TIG) is a leading European cell therapy company with a commercial product and an advanced clinical stage pipeline of adult stem cell programs. The company’s lead pr...
Founded in 2009, at Incentive, Peregrine Ventures incubator, CartiHeal is a privately held medical device company that develops proprietary implants for the regeneration of cartil...
Clinical Trials
Evaluation of GW406381 in Treating Adults With Osteoarthritis Of The Knee
This study was designed to evaluate the effectiveness of GW406381 (a COX-2 inhibitor) in treating the signs and symptoms of osteoarthritis of the knee.
Duloxetine in Osteoarthritis (OA) Pain
This study aims to determine in people with knee Osteoarthritis (OA) if relief of pain after treatment with either duloxetine or placebo is associated with changes in brain anatomy.
The purpose of this study is to monitor the stability of a total hip replacement within the thigh bone when used in artificial hip joints implanted with two different bone cements, SmartSe...
Addressing Patients' Expectations of Total Hip Arthroplasty in a Randomized Trial
The goals of this study are to develop and test an educational intervention to address patients' expectations of long-term outcomes of total hip arthroplasty.
Cost Efficacy of a Clinical Pathway to Patients Undergoing Hip and Knee Replacement Surgery
In this randomised study a proactive care and rehabilitation intervention is compared to the current care and rehabilitation in patients undergoing primary hip and knee replacement surgery...
A Comparison of Safety and Treatment in Subjects With Osteoarthritis Taking Low Dose Aspirin
The objective of this study is to compare the gastroduodenal ulceration rate, and gastrointestinal (GI) complication rate and non-steroidal anti-inflammatory drug (NSAID)-associated dyspep...
Surgery Versus no Surgery for OA of the Knee
The purpose of this trial is to evaluate the effectiveness of arthroscopy (lavage and debridement) in conjunction with the best available non-surgical treatment versus the best available n...
The primary aim of this randomised trial is to determine the effects of a short peri-operative course of treatment with a non-steroidal anti-inflammatory drug (NSAID), ibuprofen, on the lo...
Hyaluronan Versus NaCl 20 Ml Versus Placebo in Knee Osteoarthritis
251 consecutive patients with knee arthrosis were randomized to one of three interventions: Four weekly injections of 2 ml isotonic saline (placebo), 2 ml sodium hyaluronate (hyaluronan) o...
Trial of Realignment Therapy for Treatment of Medial Knee Osteoarthritis
The overall objective of this 3-year project is to determine whether the provision of realignment therapy in patients with medial knee osteoarthritis (OA) relieves knee pain and improves f...
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Medical and Biotech [MESH] Definitions
Osteoarthritis, Spine
A degenerative joint disease involving the SPINE. It is characterized by progressive deterioration of the spinal articular cartilage (CARTILAGE, ARTICULAR), usually with hardening of the subchondral bone and outgrowth of bone spurs (OSTEOPHYTE).
Viscosupplements
Viscoelastic solutions that are injected into JOINTS in order to alleviate symptoms of joint-related disorders such as OSTEOARTHRITIS.
Viscosupplementation
A therapeutic treatment typically involving INTRA-ARTICULAR INJECTIONS of HYALURONIC ACID and related compounds. The procedure is commonly used in the treatment of OSTEOARTHRITIS with the therapeutic goal to restore the viscoelasticity of SYNOVIAL FLUID, decrease pain, improve mobility and restore the natural protective functions of hyaluronan in the joint.
Genu Valgum
An inward slant of the thigh in which the knees are close together and the ankles far apart. Genu valgum can develop due to skeletal and joint dysplasias (e.g., OSTEOARTHRITIS; HURLER SYNDROME); and malnutrition (e.g., RICKETS; FLUORIDE POISONING).
Genu Varum
An outward slant of the thigh in which the knees are wide apart and the ankles close together. Genu varum can develop due to skeletal and joint dysplasia (e.g., OSTEOARTHRITIS; Blount's disease); and malnutrition (e.g., RICKETS; FLUORIDE POISONING).
