Pain - Biotech, Pharma and Life Science Channel
Pain is defined by the International Association for the Study of Pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage”.
PubMed Articles
Intrapartum sacral stress fracture due to pregnancy-related osteoporosis: a case report.
Low back pain (LBP) and hip pain frequently occur during pregnancy and postpartum period. Although pelvic and mechanic lesions of the soft tissues are most responsible for the etiology, sacral fractur...
Painful and Painless Diabetic Neuropathy: One Disease or Two?
Painful diabetic polyneuropathy (PDPN) is generally considered a variant of diabetic polyneuropathy (DPN) but the identification of distinctive aspects that characterize painful compared with painless...
Evidence-based hydro- and balneotherapy in Hungary-a systematic review and meta-analysis.
Balneotherapy is appreciated as a traditional treatment modality in medicine. Hungary is rich in thermal mineral waters. Balneotherapy has been in extensive use for centuries and its effects have been...
PURPOSE: This study is aimed at evaluating the safety and efficacy of transarterial chemoembolization (TACE) for patients with hypervascular painful metastatic spinal tumors refractory to percutaneous...
Bupivacaine crystal deposits after long-term epidural infusion.
The case of a 45-year-old male patient (body weight 52 kg, height 1.61 m) with a locally invasive gastric carcinoma infiltrating into the retroperitoneal space is reported. Because of severe cancer...
BACKGROUND: Despite well-designed concepts of perioperative pain management, recent studies have revealed that a large number of patients still suffer from unacceptable pain after surgery. The purpose...
Anesthesiological acute pain therapy in Germany : Telephone-based survey.
INTRODUCTION: The last survey of anesthesiological acute pain therapy in Germany was conducted in 1999. Since then new organisational as well as therapeutic aspects have developed. Amongst others the...
STUDY DESIGN.: Laboratory study. OBJECTIVE.: To evaluate expression of chemokine regulated and normal T cell expressed and secreted (RANTES)/C-C motif ligand 5 (CCL5) and interleukins in intervertebra...
Patient's comfort with and tolerability of thyroid core needle biopsy.
Recently, the core needle biopsy (CNB) has been proposed as a complementary test for thyroid nodules with inconclusive cytology by fine-needle aspiration (FNA). However, there have been no reports reg...
News Articles
Interferential EMS Device Designed by Better Life Devices Now Offered by Rehabmart.com
Their popular Four Channel Clinical Interferential EMS Device provides the best attributes of muscle stimulation, pain relief, relaxation and muscle toning combined into one convenient and compact FDA...
Dental patients in Encino, CA are now taking advantage of the stimulation benefits associated with the Laser Assisted New Attachment Procedure (LANAP) prior to receiving dental implants. This innovati...
Better Than Expected Long-Term Outcomes In Patients With Advanced Coronary Artery Disease
Death rates associated with patients with refractory angina, or chronic chest pain, are lower than previously considered; therefore, physicians should focus on relieving the chest pain symptoms and im...
Antibiotics useful for some types of chronic back pain
Certain types of chronic low back pain could be treated with antibiotics, according to researchers from Denmark who report that antibiotics successfully relieved pain in selected patients. They s...
Analgesia: A new player in neuropathic pain pathogenesis
Pharmacists' Picks: Topical BioMedics' Topricin Listed on Top Recommended OTC Health Products
Topricin Pain Relief and Healing Cream has been listed among nationally recommended over-the-counter (OTC) health products 2012 – 2013 in an initiative conducted by "U.S. News" in collabor...
Opioids for back pain are linked to increased risk of erectile dysfunction
Men who take opioid analgesics for back pain over a long period may have an increased risk of erectile dysfunction, a study has found.1Long term opioid use has already been linked with...
RS Medical Reaches Settlement on Investigation
International Rehabilitative Sciences, Inc., d/b/a RS Medical, today announced it has reached a settlement with the United States Department of Justice addressing actions taken by...
Little evidence for prediction rules for low back pain
(HealthDay)—Few randomized clinical trials have been done to assess clinical prediction rules for patients with lower back pain, and the trials that have been done are of low quality and do not prov...
Trillium Therapeutics completes dosing in Phase I study of TTI-1612
Trillium Therapeutics, a wholly owned subsidiary of Stem Cell Therapeutics, has completed dosing of patients with interstitial cystitis/bladder pain syndrome (IC/BPS) in first phase study of TTI-1612.
Events
13th annual Pain Therapeutics conference
Pain is the primary reason that patients seek medical care and the pain therapeutics industry is currently under financial strain.
Companies
RS Medical is the premier provider of non-invasive medical products designed to relieve pain and improve function. The company sells its products including the RS-4i Sequential St...
Physician Therapeutics is a division of Targeted Medical Pharma, Inc., a specialty pharmaceutical company that develops and sells prescription medical foods to physi...
Dolor Technologies LLC is dedicated to the development of pain management and drug delivery devices. In the U.S., Dolor Technologies currently offers SphenoCath through regional d...
National Fibromyalgia & Chronic Pain Association
NFMCPA, a not-for-profit organization, supports individuals living with fibromyalgia and other chronic pain illnesses by raising awareness through community outreach, education, a...
The Apothecary Shops is one of the foremost chains of independent full-service pharmacies with specialties in veterinary medicine, infectious disease, oncology, ophthalmology, fer...
Anesthesia Business Consultants, LLC
ABC, established in 1979, is one of the largest billing and practice management companies dedicated to the complex and intricate specialty of anesthesia and pain management. It is...
Zalicus focuses its internal drug development efforts on pain and immuno-inflammatory diseases. Our pipeline for pain includes Exalgo⢠(hydromorphone HCl) extended-release ta...
SpiderTech provides specialized kinesiology taping products that naturally reduce pain and restore strength and mobility to injured and sore muscles. The Toronto-based company has...
Zynex, Inc. (founded in 1996) engineers, manufactures, markets and sells its own design of electrotherapy medical devices in two distinct markets: standard digital electrotherapy...
Pulse Veterinary Technologies, LLC
Pulse Veterinary Technologies, LLC, located in Alpharetta, Ga., is a privately held company which develops and markets innovative, less-invasive therapies for the veterinary marke...
Clinical Trials
Pelvic Pain in Women With Endometriosis
This study will examine pelvic pain associated with endometriosis and explore better approaches to treatment. In women with endometriosis, uterine tissue grows outside the uterus. Standa...
The purpose of this study is to see if different types of surgery for lung cancer have different effects on quality of life and pain. What we learn from this study may help us find new way...
Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain
Noxious stimuli occurring intraoperatively and postoperatively generate central sensitization, decreasing pain thresholds and ultimately increasing analgesic requirements. The pathophysiol...
Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury
Imprimis Pharmaceuticals is investigating a proprietary, topical cream formulation consisting of 10% ketoprofen (containing 100 mg of ketoprofen in 1gram of cream) for the local treatment...
The Impact of Genotype on Plasma and Cerebral Spinal Fluid Pharmacokinetics of Celecoxib in Children
Background: Celecoxib is effective for reducing postoperative pain in adults. Children use celecoxib more rapidly than adults and require higher doses. Celecoxib is partially metabolized...
Neuropathic Pain Study With Botulinum Toxin A in Spinal Cord Injury Patients
The purpose of this study is to determine whether botulinum toxin A is effective in the treatment of neuropathic pain in spinal cord injury patients.
USG Nerve Blocks for ACL Reconstruction
Anterior cruciate ligament reconstruction is a routine surgical procedure. Traditional femoral/sciatic block combinations effectively reduce postoperative pain, but results in considerable...
Low-level Laser Therapy on Temporomandibular Disorder
The purpose of this study is to assess the effect of low-level laser on pain, occlusal contacts, mandibular movements and electromyography activity in the masseter and temporal muscles in...
Surgical trauma causes nerve sensitization leading to amplification and prolongation of postoperative pain. In experimental studies, pre-injury neural blockade using local anesthetics has...
Duloxetine in Osteoarthritis (OA) Pain
This study aims to determine in people with knee Osteoarthritis (OA) if relief of pain after treatment with either duloxetine or placebo is associated with changes in brain anatomy.
Videos
Three Days Grace - Pain
Music video by Three Days Grace performing Pain. (C) 2006 Zomba Recording, LLC.
Medical and Biotech [MESH] Definitions
Fasciitis, Plantar
Inflammation of the thick tissue on the bottom of the foot (plantar fascia) causing HEEL pain. The plantar fascia (also called plantar aponeurosis) are bands of fibrous tissue extending from the calcaneal tuberosity to the TOES. The etiology of plantar fasciitis remains controversial but is likely to involve a biomechanical imbalance. Though often presenting along with HEEL SPUR, they do not appear to be causally related.
Metatarsalgia
Pain in the region of the METATARSUS. It can include pain in the METATARSAL BONES; METATARSOPHALANGEAL JOINT; and/or intermetatarsal joints (TARSAL JOINTS).
Cholecystitis, Acute
Acute inflammation of the GALLBLADDER wall. It is characterized by the presence of ABDOMINAL PAIN; FEVER; and LEUKOCYTOSIS. Gallstone obstruction of the CYSTIC DUCT is present in approximately 90% of the cases.
Irritable Bowel Syndrome
A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.
Receptor, Bradykinin B2
A constitutively expressed subtype of bradykinin receptor that may play a role in the acute phase of the inflammatory and pain response. It has high specificity for intact forms of BRADYKININ and KALLIDIN. The receptor is coupled to G-PROTEIN, GQ-G11 ALPHA FAMILY and G-PROTEIN, GI-GO ALPHA FAMILY signaling proteins.
