Pain and swelling - Biotech, Pharma and Life Science Channel
PubMed Articles
Intrapartum sacral stress fracture due to pregnancy-related osteoporosis: a case report.
Low back pain (LBP) and hip pain frequently occur during pregnancy and postpartum period. Although pelvic and mechanic lesions of the soft tissues are most responsible for the etiology, sacral fractur...
CXCR3 Deficiency Prolongs Th1-Type Contact Hypersensitivity.
Sensitization and challenge using dinitrofluorobenzene (DNFB) induce contact hypersensitivity (CHS) with Th1 cell infiltration, whereas those using FITC generate CHS with Th2 cell infiltration. In thi...
A novel benzazepinone sodium channel blocker with oral efficacy in a rat model of neuropathic pain.
A series of benzazepinones were synthesized and evaluated for block of Nav1.7 sodium channels. Compound 30 from this series displayed potent channel block, good selectivity versus other targets, and d...
Does opioid pain medication use affect the outcome of patients with lumbar disc herniation?
STUDY DESIGN.: Subgroup analysis of prospective, randomized cohort. OBJECTIVE.: To review the results of patients who received opioid pain medications during treatment compared with that of patients w...
Obstructive hydrocephalus due to CNS toxocariasis.
A 46-year-old man developed intermittent headache, diplopia, and visual obscuration for two months. Funduscopic examination showed optic disk swelling in both eyes. Brain MRI exhibited hydrocephalus a...
Immunoinflammatory responses in gastrointestinal tract injury and recovery.
Inflammation is a non-specific immune response to infection, irritation or other injury, the key features being redness, warmth, swelling and pain. A number of mediators are released which alter the r...
Skin vasodilation and analgesic effect of a topical nitric oxide-releasing hydrogel.
New approaches based on topical treatments are needed for treating pain and impaired dermal blood flow. We used a topical Pluronic F127 hydrogel containing S-nitrosoglutathione (GSNO) as a prodrug to...
Clinical Practice: Chronic fatigue syndrome.
The diagnosis chronic fatigue syndrome (CFS) was conceptualized in the mid-1980s. It is a clinically defined condition characterized by severe and disabling new onset fatigue with at least four additi...
Bisphosphonate (BP)-related osteonecrosis of the jaw (BRONJ) presents with necrotic bone in the mouth in the setting of BP exposure. It has been studied in cancer patients taking high-dose BP, but BRO...
Takotsubo cardiomyopathy after bisoprolol withdrawal and open appendectomy.
Takotsubo cardiomyopathy (TTC) is an acute cardiac syndrome characterized by transient regional wall motion abnormalities of the left ventricular apex or midventricle. Patients often present with ches...
News Articles
The US Drug Watchdog says, "The reason there is ongoing national litigation involving the DePuy Pinnacle metal on metal hip implant is premature failure issues, and we think the easiest way for a...
On June 3, 2013, the International Adhesions Society (IAS) presented recommendations to the Interagency Pain Research Coordinating Committee (IPRCC), advocating for efforts to address gender disparity...
HPV Laser Surgery for Genital Warts: What are the Side Effects?; polyDNA Answers Survey Questions
In its June, 2013 survey, polyDNA found that three out of four respondents considering laser surgery to remove HPV genital warts were unaware of side effects. polyDNA highlights these side effects and...
Rational Biological Source Of Pain Found In The Skin Of Patients With Fibromyalgia
Fibromyalgia, a painful condition affecting approximately 10 million people in the U.S., is not imaginary after all, as some doctors have believed. A discovery, published this month in PAIN MEDICINE (...
Spinal Injection Therapy for Low Back Pain Spinal Injection Therapy for Low Back Pain
Low back pain is commonly reported by patients in primary care and will affect most adults at some time during their lifetime. The socioeconomic burden of low back pain is high. In the United States,...
First Robot-Guided Sacroiliac (SI) Fusion Surgery in North America Is Performed
RESTON, VA--(Marketwired - June 19, 2013) - Dr. Christopher R. Good, Spinal Specialist at the Virginia Spine Institute, performed the first robot-guided sacroiliac joint (SI) fusion procedu...
EMA issues warnings over codeine use
Children and young adults who have had surgery to remove their tonsils or adenoids to treat sleep apnoea should not receive codeine as pain relief, the European Medicines Agency has stated. The warni...
MRI May Detect Meningitis From Tainted Steroids
People who may have been injected with contaminated steroids can undergo an MRI scan to check for signs of infection, even if they do not have symptoms, according to a new study published in JAMA. A g...
Past care tied to later treatment's success
NEW YORK (Reuters Health) - If a person doesn't have much success with one pain treatment, they may say the next one they try doesn't work so great either, suggests a new study from Germany.
House Passage of Pain-Capable Unborn Child Protection Act Conforms Law to Modern Science
WASHINGTON, June 18, 2013 /PRNewswire-USNewswire/ -- Family Research Council (FRC) praised the passage of U.S. Rep. Trent Franks' (R-AZ) Pain-Capable Unborn Child Protection Act (H.R. 1797) on the Hou...
Events
None
Companies
Vertical Pharmaceuticals, Inc.
Vertical Pharmaceuticals, Inc. is a privately owned pharmaceutical company founded in 2003 with a clear focus in mind â to develop, market, and acquire products offering ther...
NeuroMetrix is a science-based health care company transforming patient care through neurotechnology. To date, our focus has been primarily on the assessment of neuropathies. We a...
Ocular Therapeutix, Inc. is a privately held company based in Bedford, MA, focused on the development and commercialization of ophthalmic therapeutic products using its proprietar...
Dr. Reddyâs Laboratories Ltd. (NYSE: RDY) is an integrated global pharmaceutical company, committed to providing affordable and innovative medicines for healthier lives. Thro...
Civitas is a privately held pharmaceutical company focused on developing products with a clinically proven dry powder pulmonary delivery platform. The proprietary dry powder and d...
Kineta is a Seattle-based privately held biotechnology company specializing in clinical advancement of novel drug candidates derived from leading edge scientific research. Our wor...
THE Surgical Hospital of Phoenix
THE Surgical Hospital of Phoenix, the first licensed surgical specialty facility of its kind in Arizona, first opened its doors in May of 2005. Specializing in spine, orthopedics,...
RS Medical is the premier provider of non-invasive medical products designed to relieve pain and improve function. The company sells its products including the RS-4i Sequential St...
Physician Therapeutics is a division of Targeted Medical Pharma, Inc., a specialty pharmaceutical company that develops and sells prescription medical foods to physi...
Dolor Technologies LLC is dedicated to the development of pain management and drug delivery devices. In the U.S., Dolor Technologies currently offers SphenoCath through regional d...
Clinical Trials
Oral Collagen for Rheumatoid Arthritis
Rheumatoid arthritis (RA) is an autoimmune disease characterized by swelling and inflammation of the joints. In RA, the immune system attacks a person's own cells inside joints, eventually...
A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-181)(COMPLETED)
The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.
Safety of Driving After Minor Surgery With Monitored Anesthesia Care
Patients are currently advised to refrain from driving motor vehicles or using public transportation unescorted for a 24 hour period if they undergo any minor ambulatory surgical procedure...
Naproxen Sodium Extended-Release Actual Use Study
The purpose of this Study is to assess how subjects will use the investigational product in an uncontrolled, naturalistic environment.
Safe Administration of Flu Vaccine to Egg Allergic Children
Historically, providing influenza vaccination of egg allergic children and young adults (EAC) with a history of anaphylaxis to egg, or other severe symptoms of an allergic reaction to egg...
A Trial of Gabapentin in Vulvodynia: Biological Correlates of Response
The Specific aims of this project are to (1) test the prediction that pain from tampon insertion (primary outcome measure) is lower in PVD patients when treated with gabapentin compared to...
The purpose of this study is to see if different types of surgery for lung cancer have different effects on quality of life and pain. What we learn from this study may help us find new way...
Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain
Noxious stimuli occurring intraoperatively and postoperatively generate central sensitization, decreasing pain thresholds and ultimately increasing analgesic requirements. The pathophysiol...
Pelvic Pain in Women With Endometriosis
This study will examine pelvic pain associated with endometriosis and explore better approaches to treatment. In women with endometriosis, uterine tissue grows outside the uterus. Standa...
Low-level Laser Therapy on Temporomandibular Disorder
The purpose of this study is to assess the effect of low-level laser on pain, occlusal contacts, mandibular movements and electromyography activity in the masseter and temporal muscles in...
Videos
knee pain and swelling
http://www.ThePainFreeKnee.com - In this video we cover why you may have knee pain and swelling and some specific exercises you can do to get relief. Be sure...
Medical and Biotech [MESH] Definitions
Fasciitis, Plantar
Inflammation of the thick tissue on the bottom of the foot (plantar fascia) causing HEEL pain. The plantar fascia (also called plantar aponeurosis) are bands of fibrous tissue extending from the calcaneal tuberosity to the TOES. The etiology of plantar fasciitis remains controversial but is likely to involve a biomechanical imbalance. Though often presenting along with HEEL SPUR, they do not appear to be causally related.
Metatarsalgia
Pain in the region of the METATARSUS. It can include pain in the METATARSAL BONES; METATARSOPHALANGEAL JOINT; and/or intermetatarsal joints (TARSAL JOINTS).
Cholecystitis, Acute
Acute inflammation of the GALLBLADDER wall. It is characterized by the presence of ABDOMINAL PAIN; FEVER; and LEUKOCYTOSIS. Gallstone obstruction of the CYSTIC DUCT is present in approximately 90% of the cases.
Irritable Bowel Syndrome
A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.
Receptor, Bradykinin B2
A constitutively expressed subtype of bradykinin receptor that may play a role in the acute phase of the inflammatory and pain response. It has high specificity for intact forms of BRADYKININ and KALLIDIN. The receptor is coupled to G-PROTEIN, GQ-G11 ALPHA FAMILY and G-PROTEIN, GI-GO ALPHA FAMILY signaling proteins.
